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ONTOLOGY REPORT - ANNOTATIONS


Term:pentetrazol
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Accession:CHEBI:34910 term browser browse the term
Definition:An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Synonyms:related_synonym: 1,5-pentamethylenetetrazole;   6,7,8,9-tetrahydro-5-azepotetrazole;   6,7,8,9-tetrahydro-5H-tetrazolo[1,5-a]azepine;   7,8,9,10-tetrazabicyclo[5.3.0]-8,10-decadiene;   Cardiazol;   Cardiazole;   Cardifortan;   Cardiotonicum;   Cardosal;   Cardosan;   Cenalene-M;   Cenazol;   Coranormol;   Coratoline;   Corazol;   Corazole;   Corvasol;   Coryvet;   Deumacard;   Diovascole;   Formula=C6H10N4;   Gewazol;   InChI=1S/C6H10N4/c1-2-4-6-7-8-9-10(6)5-3-1/h1-5H2;   InChIKey=CWRVKFFCRWGWCS-UHFFFAOYSA-N;   Kardiazol;   Korazol;   Metrazol;   Pentylenetetrazole;   Phrenazol;   SMILES=C1CCc2nnnn2CC1;   Ventrazol;   alpha,beta-cyclopentamethylenetetrazole;   pentamethylene-1,5-tetrazole;   pentetrazolum;   pentylenetetrazol
 xref: CAS:54-95-5 "ChemIDplus";   CAS:54-95-5 "KEGG COMPOUND";   CAS:54-95-5 "NIST Chemistry WebBook";   Drug_Central:3428 "DrugCentral";   KEGG:C13692;   KEGG:D07409;   LINCS:LSM-3287
 xref_mesh: MESH:D010433
 xref: PMID:19797046 "Europe PMC";   PMID:21689733 "Europe PMC";   PMID:22049436 "Europe PMC";   PMID:23852314 "Europe PMC";   PMID:23893477 "Europe PMC";   PMID:24397543 "Europe PMC";   Patent:US1564631;   Patent:US1599493;   Reaxys:135492 "Reaxys";   Wikipedia:Pentylenetetrazol


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pentetrazol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:6480464
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:6480464
G Alad aminolevulinate dehydratase JBrowse link 5 78,368,867 78,379,206 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:6480464
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Gabra1 gamma-aminobutyric acid type A receptor alpha1 subunit JBrowse link 10 27,310,718 27,371,802 RGD:6480464
G Gabra2 gamma-aminobutyric acid type A receptor alpha2 subunit JBrowse link 14 39,662,411 39,801,082 RGD:6480464
G Gabrb2 gamma-aminobutyric acid type A receptor beta 2 subunit JBrowse link 10 27,973,694 28,193,072 RGD:6480464
G Gabrg2 gamma-aminobutyric acid type A receptor gamma 2 subunit JBrowse link 10 27,090,913 27,179,786 RGD:6480464
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:6480464
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 JBrowse link 3 176,585,897 176,645,029 RGD:6480464
G Mpdz multiple PDZ domain crumbs cell polarity complex component JBrowse link 5 99,413,184 99,566,356 RGD:6480464
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 JBrowse link 7 142,899,358 142,920,216 RGD:6480464
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 JBrowse link 3 43,111,258 43,128,391 RGD:6480464
G Nrp2 neuropilin 2 JBrowse link 9 69,496,875 69,609,802 RGD:6480464
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:6480464
G Oprk1 opioid receptor, kappa 1 JBrowse link 5 13,742,655 13,760,460 RGD:6480464
G Pam peptidylglycine alpha-amidating monooxygenase JBrowse link 9 111,028,543 111,177,588 RGD:6480464
G Slc6a2 solute carrier family 6 member 2 JBrowse link 19 15,391,682 15,431,274 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    chemical entity 19667
      atom 19665
        nonmetal atom 19531
          nitrogen atom 18301
            nitrogen molecular entity 18301
              organonitrogen compound 18076
                organonitrogen heterocyclic compound 16961
                  pentetrazol 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      p-block molecular entity 19545
                        carbon group molecular entity 19428
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic heterocyclic compound 18157
                                  organic heteropolycyclic compound 17423
                                    organic heterobicyclic compound 15889
                                      pentetrazol 24
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.