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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cefonicid
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Accession:CHEBI:3491 term browser browse the term
Definition:A cephalosporin bearing {[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and (R)-2-hydroxy-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton.
Synonyms:exact_synonym: 6beta-[(2R)-2-hydroxy-2-phenylacetamido]-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)ceph-3-em-4-carboxylic acid
 related_synonym: (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   Formula=C18H18N6O8S3;   InChI=1S/C18H18N6O8S3/c25-13(9-4-2-1-3-5-9)14(26)19-11-15(27)24-12(17(28)29)10(6-33-16(11)24)7-34-18-20-21-22-23(18)8-35(30,31)32/h1-5,11,13,16,25H,6-8H2,(H,19,26)(H,28,29)(H,30,31,32)/t11-,13-,16-/m1/s1;   InChIKey=DYAIAHUQIPBDIP-AXAPSJFSSA-N;   SMILES=[H][C@]12SCC(CSc3nnnn3CS(O)(=O)=O)=C(N1C(=O)[C@H]2NC(=O)[C@H](O)c1ccccc1)C(O)=O;   cefonicido;   cefonicidum
 xref: Beilstein:8175049;   CAS:61270-58-4;   DrugBank:DB01328;   Drug_Central:542;   KEGG:C06882;   KEGG:D07644
 xref_mesh: MESH:D015790
 xref: PMID:12041774;   PMID:21425867;   PMID:29017833;   Patent:DE2611270;   Patent:US4048311;   Patent:US4093723;   Patent:US4159373;   Reaxys:8175049;   Wikipedia:Cefonicid
 cyclic_relationship: is_conjugate_acid_of CHEBI:52441


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cefonicid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a20 solute carrier family 25 member 20 multiple interactions EXP Cefonicid binds to and results in decreased activity of SLC25A20 protein; Cefonicid inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine] CTD PMID:18452908 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      biological role 19723
        antimicrobial agent 17374
          antibacterial agent 13452
            antibacterial drug 3171
              cefonicid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            organic group 18603
                              organic divalent group 18594
                                organodiyl group 18594
                                  carbonyl group 18507
                                    carbonyl compound 18507
                                      carboxylic acid 18159
                                        carboacyl group 17415
                                          univalent carboacyl group 17415
                                            carbamoyl group 17211
                                              carboxamide 17211
                                                lactam 8048
                                                  beta-lactam 793
                                                    beta-lactam antibiotic 778
                                                      cephem 543
                                                        cephalosporin 542
                                                          cefonicid 1
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