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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Olprinone hydrochloride
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Accession:CHEBI:34902 term browser browse the term
Definition:An organic molecular entity that has formula C14H10N4O.HCl.
Synonyms:related_synonym: E 1020;   Formula=C14H10N4O.HCl;   InChI=1S/C14H10N4O.ClH/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10;/h2-6,8H,1H3,(H,17,19);1H;   InChIKey=PWTBMBAQRAOAFF-UHFFFAOYSA-N;   SMILES=Cl.Cc1[nH]c(=O)c(cc1-c1ccc2nccn2c1)C#N
 xref: CAS:119615-63-3;   KEGG:C13546
 xref_mesh: MESH:C059498


show annotations for term's descendants           Sort by:
Olprinone hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases activity
multiple interactions		 EXP olprinone results in increased activity of AKT1 protein
zinc protoporphyrin inhibits the reaction [olprinone results in increased activity of AKT1 protein]		 CTD PMID:19387321 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP olprinone results in increased expression of and results in increased activity of HMOX1 protein; zinc protoporphyrin inhibits the reaction [olprinone results in increased activity of HMOX1 protein] CTD PMID:19387321 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Pde3a phosphodiesterase 3A decreases activity ISO olprinone results in decreased activity of PDE3A protein CTD PMID:16325808 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    chemical entity 19920
      atom 19892
        nonmetal atom 19849
          carbon atom 19802
            organic molecular entity 19775
              Olprinone hydrochloride 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            Olprinone hydrochloride 3
paths to the root