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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Norethynodrel
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Accession:CHEBI:34895 term browser browse the term
Definition:An oxo steroid that has formula C20H26O2.
Synonyms:related_synonym: Formula=C20H26O2;   InChI=1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,16-18,22H,4-12H2,2H3/t16-,17-,18+,19+,20+/m1/s1;   InChIKey=ICTXHFFSOAJUMG-SLHNCBLASA-N;   SMILES=C[C@]12CC[C@H]3[C@@H](CCC4=C3CCC(=O)C4)[C@@H]1CC[C@@]2(O)C#C;   norethinodrel;   noretynodrel
 xref: CAS:68-23-5;   Drug_Central:1965;   KEGG:C14249;   KEGG:D05207;   LINCS:LSM-3807
 xref_mesh: MESH:D009641


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Norethynodrel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
affects binding
ISO
EXP
Norethynodrel binds to and results in increased activity of AR protein
Norethynodrel binds to AR protein
CTD PMID:14565775 PMID:19833195 PMID:20438827 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO Norethynodrel binds to ESR1 protein
Norethynodrel binds to and results in increased activity of ESR1 protein
CTD PMID:20074635 PMID:20362049 PMID:20435135 PMID:29162470 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO fulvestrant inhibits the reaction [Norethynodrel results in increased activity of FASN protein]; Mifepristone inhibits the reaction [Norethynodrel results in increased activity of FASN protein]; Norethynodrel results in increased activity of and results in increased expression of FASN protein CTD PMID:15870863 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO Norethynodrel binds to SHBG protein CTD PMID:25349334 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    chemical entity 19771
      group 19689
        inorganic group 19168
          oxo group 18505
            organic oxo compound 18505
              carbonyl compound 18505
                ketone 16829
                  oxo steroid 9722
                    Norethynodrel 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    p-block element atom 19658
                      carbon group element atom 19574
                        carbon atom 19564
                          organic molecular entity 19564
                            organic group 18599
                              organic divalent group 18590
                                organodiyl group 18590
                                  carbonyl group 18505
                                    carbonyl compound 18505
                                      ketone 16829
                                        oxo steroid 9722
                                          Norethynodrel 4
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