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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:mirex
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Accession:CHEBI:34852 term browser browse the term
Definition:A chlorocarbon that has formula C10Cl12.
Synonyms:exact_synonym: 1,1a,2,2,3,3a,4,5,5,5a,5b,6-dodecachlorooctahydro-1H-1,3,4-(methanetriyl)cyclobuta[cd]pentalene
 related_synonym: 1,2,3,4,5,5,6,7,8,9,10,10-dodecachloropentacyclo[5.3.0.0(2,6).0(3,9).0(4,8)]decane;   CG-1283;   Dechlorane;   Formula=C10Cl12;   InChI=1S/C10Cl12/c11-1-2(12)7(17)4(14)3(13,5(1,15)9(7,19)20)6(1,16)10(21,22)8(2,4)18;   InChIKey=GVYLCNUFSHDAAW-UHFFFAOYSA-N;   SMILES=ClC1(Cl)C2(Cl)C3(Cl)C4(Cl)C(Cl)(Cl)C5(Cl)C3(Cl)C1(Cl)C5(Cl)C24Cl;   dodecachlorooctahydro-1,3,4-metheno-2H-cyclobuta[cd]pentalene;   perchlorodihomocubane;   perchloropentacyclo[5.2.1.0(2,6).0(3,9).0(5,8)]decane;   perchloropentacyclodecane
 xref: Beilstein:2010845;   CAS:2385-85-5;   Gmelin:1789502;   HMDB:HMDB0059573;   KEGG:C14184
 xref_mesh: MESH:D008917
 xref: PPDB:1294;   Patent:US2702305;   Patent:US2724730;   Reaxys:2010845;   Wikipedia:Mirex


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mirex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression EXP Mirex results in decreased expression of ABCC6 mRNA CTD PMID:23153324 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Mirex results in increased expression of ABCG5 mRNA CTD PMID:23153324 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Aqp9 aquaporin 9 decreases expression EXP Mirex results in decreased expression of AQP9 mRNA CTD PMID:23153324 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Ar androgen receptor multiple interactions ISO [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Hydrocarbons, Chlorinated] inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:21295777 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP Mirex results in decreased expression of ATP1B1 mRNA CTD PMID:23153324 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 decreases expression EXP Mirex results in decreased expression of ATP2C1 mRNA CTD PMID:23153324 NCBI chr 8:106,034,777...106,155,854
Ensembl chr 8:106,034,636...106,156,006 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression EXP Mirex results in increased expression of BCAT1 mRNA CTD PMID:23153324 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Ccnb1 cyclin B1 increases expression EXP Mirex results in increased expression of CCNB1 mRNA CTD PMID:23153324 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 increases expression EXP Mirex results in increased expression of CCNB2 mRNA CTD PMID:23153324 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression EXP Mirex results in increased expression of CDKN3 mRNA CTD PMID:23153324 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cenpe centromere protein E increases expression EXP Mirex results in increased expression of CENPE mRNA CTD PMID:23153324 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit decreases expression EXP Mirex results in decreased expression of CHRNA1 mRNA CTD PMID:23153324 NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840 		JBrowse link
G Csf3 colony stimulating factor 3 increases expression EXP Mirex results in increased expression of CSF3 mRNA CTD PMID:23153324 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Mirex results in increased expression of CYP2B1 mRNA; Mirex results in increased expression of CYP2B1 protein CTD PMID:1715015 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Mirex results in increased expression of CYP2B2 mRNA; Mirex results in increased expression of CYP2B2 protein CTD PMID:1715015 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Mirex results in increased expression of and results in increased activity of CYP2B10 protein CTD PMID:8722114 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression EXP Mirex results in decreased expression of CYP2E1 protein CTD PMID:3113478 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Ect2 epithelial cell transforming 2 increases expression EXP Mirex results in increased expression of ECT2 mRNA CTD PMID:23153324 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 increases expression EXP Mirex results in increased expression of ELOVL7 mRNA CTD PMID:23153324 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
G Ereg epiregulin increases expression EXP Mirex results in increased expression of EREG mRNA CTD PMID:23153324 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA CTD PMID:21295777 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Hk2 hexokinase 2 increases expression EXP Mirex results in increased expression of HK2 mRNA CTD PMID:23153324 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Kif18b kinesin family member 18B increases expression EXP Mirex results in increased expression of KIF18B mRNA CTD PMID:23153324 NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850 		JBrowse link
G Lmnb1 lamin B1 increases expression EXP Mirex results in increased expression of LMNB1 mRNA CTD PMID:23153324 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502 		JBrowse link
G Lrrc1 leucine rich repeat containing 1 increases expression EXP Mirex results in increased expression of LRRC1 mRNA CTD PMID:23153324 NCBI chr 8:78,239,897...78,407,347
Ensembl chr 8:78,239,900...78,406,490 		JBrowse link
G Meox2 mesenchyme homeobox 2 increases expression EXP Mirex results in increased expression of MEOX2 mRNA CTD PMID:23153324 NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467 		JBrowse link
G Mmd monocyte to macrophage differentiation-associated increases expression EXP Mirex results in increased expression of MMD mRNA CTD PMID:23153324 NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase decreases expression EXP Mirex results in decreased expression of NNT mRNA CTD PMID:23153324 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP Mirex results in decreased expression of NR3C1 protein CTD PMID:1638671 PMID:1673321 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nt5dc2 5'-nucleotidase domain containing 2 increases expression EXP Mirex results in increased expression of NT5DC2 mRNA CTD PMID:23153324 NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,322,236...6,330,537 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity EXP Mirex results in increased activity of ODC1 protein CTD PMID:2283661 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression EXP Mirex results in increased expression of PTTG1 mRNA CTD PMID:23153324 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Rfc4 replication factor C subunit 4 increases expression EXP Mirex results in increased expression of RFC4 mRNA CTD PMID:23153324 NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122 		JBrowse link
G Serpinb2 serpin family B member 2 increases expression EXP Mirex results in increased expression of SERPINB2 mRNA CTD PMID:23153324 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP Mirex results in decreased expression of SLC10A1 mRNA CTD PMID:23153324 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 decreases expression EXP Mirex results in decreased expression of SLC16A1 mRNA CTD PMID:23153324 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611 		JBrowse link
G Slc16a4 solute carrier family 16, member 4 decreases expression EXP Mirex results in decreased expression of SLC16A4 mRNA CTD PMID:23153324 NCBI chr 2:194,911,075...194,933,162
Ensembl chr 2:194,911,236...194,933,117 		JBrowse link
G Slc16a7 solute carrier family 16 member 7 decreases expression EXP Mirex results in decreased expression of SLC16A7 mRNA CTD PMID:23153324 NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994 		JBrowse link
G Slc17a3 solute carrier family 17 member 3 decreases expression EXP Mirex results in decreased expression of SLC17A3 mRNA CTD PMID:23153324 NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256 		JBrowse link
G Slc17a5 solute carrier family 17 member 5 decreases expression EXP Mirex results in decreased expression of SLC17A5 mRNA CTD PMID:23153324 NCBI chr 8:79,394,416...79,429,387 JBrowse link
G Slc19a2 solute carrier family 19 member 2 decreases expression EXP Mirex results in decreased expression of SLC19A2 mRNA CTD PMID:23153324 NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression EXP Mirex results in decreased expression of SLC2A2 mRNA CTD PMID:23153324 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Slc31a2 solute carrier family 31 member 2 decreases expression EXP Mirex results in decreased expression of SLC31A2 mRNA CTD PMID:23153324 NCBI chr 5:75,738,008...75,748,542
Ensembl chr 5:75,738,024...75,748,542 		JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Mirex results in decreased expression of SLC34A2 mRNA CTD PMID:23153324 NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436 		JBrowse link
G Slc38a1 solute carrier family 38, member 1 increases expression EXP Mirex results in increased expression of SLC38A1 mRNA CTD PMID:23153324 NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 increases expression EXP Mirex results in increased expression of SLC4A7 mRNA CTD PMID:23153324 NCBI chr15:10,585,307...10,664,780
Ensembl chr15:10,588,979...10,664,781 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 decreases expression EXP Mirex results in decreased expression of SLC5A6 mRNA CTD PMID:23153324 NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712 		JBrowse link
G Slc7a2 solute carrier family 7 member 2 decreases expression EXP Mirex results in decreased expression of SLC7A2 mRNA CTD PMID:23153324 NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784 		JBrowse link
G Slc7a6 solute carrier family 7 member 6 decreases expression EXP Mirex results in decreased expression of SLC7A6 mRNA CTD PMID:23153324 NCBI chr19:34,073,472...34,100,268
Ensembl chr19:34,074,286...34,100,268 		JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP [Mirex co-treated with Corticosterone] results in increased activity of TAT protein CTD PMID:2893471 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 increases expression EXP Mirex results in increased expression of TRIP13 mRNA CTD PMID:23153324 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      chemical role 19422
        environmental contaminant 18822
          persistent organic pollutant 16662
            mirex 51
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            heteroorganic entity 19459
                              organohalogen compound 18484
                                organochlorine compound 18279
                                  organochlorine pesticide 7545
                                    organochlorine insecticide 6849
                                      mirex 51
paths to the root