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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:mirex
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Accession:CHEBI:34852 term browser browse the term
Definition:A chlorocarbon that has formula C10Cl12.
Synonyms:exact_synonym: 1,1a,2,2,3,3a,4,5,5,5a,5b,6-dodecachlorooctahydro-1H-1,3,4-(methanetriyl)cyclobuta[cd]pentalene
 related_synonym: 1,2,3,4,5,5,6,7,8,9,10,10-dodecachloropentacyclo[5.3.0.0(2,6).0(3,9).0(4,8)]decane;   CG-1283;   Dechlorane;   Formula=C10Cl12;   InChI=1S/C10Cl12/c11-1-2(12)7(17)4(14)3(13,5(1,15)9(7,19)20)6(1,16)10(21,22)8(2,4)18;   InChIKey=GVYLCNUFSHDAAW-UHFFFAOYSA-N;   SMILES=ClC1(Cl)C2(Cl)C3(Cl)C4(Cl)C(Cl)(Cl)C5(Cl)C3(Cl)C1(Cl)C5(Cl)C24Cl;   dodecachlorooctahydro-1,3,4-metheno-2H-cyclobuta[cd]pentalene;   perchlorodihomocubane;   perchloropentacyclo[5.2.1.0(2,6).0(3,9).0(5,8)]decane;   perchloropentacyclodecane
 xref: Beilstein:2010845;   CAS:2385-85-5;   Gmelin:1789502;   HMDB:HMDB0059573;   KEGG:C14184
 xref_mesh: MESH:D008917
 xref: PPDB:1294;   Patent:US2702305;   Patent:US2724730;   Reaxys:2010845;   Wikipedia:Mirex


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mirex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression EXP Mirex results in decreased expression of ABCC6 mRNA CTD PMID:23153324 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Mirex results in increased expression of ABCG5 mRNA CTD PMID:23153324 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Aqp9 aquaporin 9 decreases expression EXP Mirex results in decreased expression of AQP9 mRNA CTD PMID:23153324 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Ar androgen receptor multiple interactions ISO [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Hydrocarbons, Chlorinated] inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:21295777 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP Mirex results in decreased expression of ATP1B1 mRNA CTD PMID:23153324 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 decreases expression EXP Mirex results in decreased expression of ATP2C1 mRNA CTD PMID:23153324 NCBI chr 8:113,953,959...114,039,965
Ensembl chr 8:113,955,647...114,013,623
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression EXP Mirex results in increased expression of BCAT1 mRNA CTD PMID:23153324 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Ccnb1 cyclin B1 increases expression EXP Mirex results in increased expression of CCNB1 mRNA CTD PMID:23153324 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 increases expression EXP Mirex results in increased expression of CCNB2 mRNA CTD PMID:23153324 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression EXP Mirex results in increased expression of CDKN3 mRNA CTD PMID:23153324 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cenpe centromere protein E increases expression EXP Mirex results in increased expression of CENPE mRNA CTD PMID:23153324 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747
JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit decreases expression EXP Mirex results in decreased expression of CHRNA1 mRNA CTD PMID:23153324 NCBI chr 3:60,445,657...60,460,724
Ensembl chr 3:60,445,666...60,460,724
JBrowse link
G Csf3 colony stimulating factor 3 increases expression EXP Mirex results in increased expression of CSF3 mRNA CTD PMID:23153324 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression
multiple interactions
EXP
ISO
Mirex results in increased expression of CYP2B1 mRNA; Mirex results in increased expression of CYP2B1 protein
Mirex results in increased expression of and results in increased activity of CYP2B10 protein
CTD PMID:1715015 PMID:8722114 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Mirex results in increased expression of CYP2B2 mRNA; Mirex results in increased expression of CYP2B2 protein CTD PMID:1715015 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression EXP Mirex results in decreased expression of CYP2E1 protein CTD PMID:3113478 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Ect2 epithelial cell transforming 2 increases expression EXP Mirex results in increased expression of ECT2 mRNA CTD PMID:23153324 NCBI chr 2:112,769,385...112,831,476
Ensembl chr 2:112,769,385...112,831,476
JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 increases expression EXP Mirex results in increased expression of ELOVL7 mRNA CTD PMID:23153324 NCBI chr 2:40,373,211...40,386,643
Ensembl chr 2:40,373,211...40,386,669
JBrowse link
G Ereg epiregulin increases expression EXP Mirex results in increased expression of EREG mRNA CTD PMID:23153324 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA CTD PMID:21295777 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Hk2 hexokinase 2 increases expression EXP Mirex results in increased expression of HK2 mRNA CTD PMID:23153324 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Kif18b kinesin family member 18B increases expression EXP Mirex results in increased expression of KIF18B mRNA CTD PMID:23153324 NCBI chr10:91,008,294...91,027,760
Ensembl chr10:91,008,269...91,027,738
JBrowse link
G Lmnb1 lamin B1 increases expression EXP Mirex results in increased expression of LMNB1 mRNA CTD PMID:23153324 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
JBrowse link
G Lrrc1 leucine rich repeat containing 1 increases expression EXP Mirex results in increased expression of LRRC1 mRNA CTD PMID:23153324 NCBI chr 8:84,721,621...84,835,074
Ensembl chr 8:84,720,551...84,835,060
JBrowse link
G Meox2 mesenchyme homeobox 2 increases expression EXP Mirex results in increased expression of MEOX2 mRNA CTD PMID:23153324 NCBI chr 6:56,625,768...56,689,195
Ensembl chr 6:56,625,650...56,689,238
JBrowse link
G Mmd monocyte to macrophage differentiation-associated increases expression EXP Mirex results in increased expression of MMD mRNA CTD PMID:23153324 NCBI chr10:77,687,964...77,783,737
Ensembl chr10:77,755,216...77,783,779
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase decreases expression EXP Mirex results in decreased expression of NNT mRNA CTD PMID:23153324 NCBI chr 2:52,189,523...52,283,095
Ensembl chr 2:52,189,529...52,282,548
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP Mirex results in decreased expression of NR3C1 protein CTD PMID:1638671 PMID:1673321 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nt5dc2 5'-nucleotidase domain containing 2 increases expression EXP Mirex results in increased expression of NT5DC2 mRNA CTD PMID:23153324 NCBI chr16:7,212,488...7,220,541
Ensembl chr16:7,212,488...7,220,540
JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity EXP Mirex results in increased activity of ODC1 protein CTD PMID:2283661 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression EXP Mirex results in increased expression of PTTG1 mRNA CTD PMID:23153324 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
JBrowse link
G Rfc4 replication factor C subunit 4 increases expression EXP Mirex results in increased expression of RFC4 mRNA CTD PMID:23153324 NCBI chr11:81,358,592...81,373,044
Ensembl chr11:81,358,592...81,373,043
JBrowse link
G Serpinb2 serpin family B member 2 increases expression EXP Mirex results in increased expression of SERPINB2 mRNA CTD PMID:23153324 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP Mirex results in decreased expression of SLC10A1 mRNA CTD PMID:23153324 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc16a1 solute carrier family 16 member 1 decreases expression EXP Mirex results in decreased expression of SLC16A1 mRNA CTD PMID:23153324 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc16a4 solute carrier family 16, member 4 decreases expression EXP Mirex results in decreased expression of SLC16A4 mRNA CTD PMID:23153324 NCBI chr 2:210,045,122...210,161,017
Ensembl chr 2:210,045,161...210,068,502
JBrowse link
G Slc16a7 solute carrier family 16 member 7 decreases expression EXP Mirex results in decreased expression of SLC16A7 mRNA CTD PMID:23153324 NCBI chr 7:68,438,341...68,606,312
Ensembl chr 7:68,446,193...68,549,763
JBrowse link
G Slc17a3 solute carrier family 17 member 3 decreases expression EXP Mirex results in decreased expression of SLC17A3 mRNA CTD PMID:23153324 NCBI chr17:43,518,760...43,545,160
Ensembl chr17:43,518,655...43,543,185
JBrowse link
G Slc17a5 solute carrier family 17 member 5 decreases expression EXP Mirex results in decreased expression of SLC17A5 mRNA CTD PMID:23153324 NCBI chr 8:85,891,245...85,926,466
Ensembl chr 8:85,891,257...85,926,450
JBrowse link
G Slc19a2 solute carrier family 19 member 2 decreases expression EXP Mirex results in decreased expression of SLC19A2 mRNA CTD PMID:23153324 NCBI chr13:82,552,586...82,566,586
Ensembl chr13:82,552,550...82,566,586
JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression EXP Mirex results in decreased expression of SLC2A2 mRNA CTD PMID:23153324 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc31a2 solute carrier family 31 member 2 decreases expression EXP Mirex results in decreased expression of SLC31A2 mRNA CTD PMID:23153324 NCBI chr 5:78,120,606...78,131,111
Ensembl chr 5:78,120,607...78,131,114
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Mirex results in decreased expression of SLC34A2 mRNA CTD PMID:23153324 NCBI chr14:60,257,211...60,276,516
Ensembl chr14:60,256,712...60,276,794
JBrowse link
G Slc38a1 solute carrier family 38, member 1 increases expression EXP Mirex results in increased expression of SLC38A1 mRNA CTD PMID:23153324 NCBI chr 7:137,970,555...138,040,098
Ensembl chr 7:137,975,549...138,039,984
JBrowse link
G Slc4a7 solute carrier family 4 member 7 increases expression EXP Mirex results in increased expression of SLC4A7 mRNA CTD PMID:23153324 NCBI chr15:11,832,611...11,912,923
Ensembl chr15:11,836,286...11,912,916
JBrowse link
G Slc5a6 solute carrier family 5 member 6 decreases expression EXP Mirex results in decreased expression of SLC5A6 mRNA CTD PMID:23153324 NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116
JBrowse link
G Slc7a2 solute carrier family 7 member 2 decreases expression EXP Mirex results in decreased expression of SLC7A2 mRNA CTD PMID:23153324 NCBI chr16:54,459,409...54,513,349
Ensembl chr16:54,460,067...54,513,349
JBrowse link
G Slc7a6 solute carrier family 7 member 6 decreases expression EXP Mirex results in decreased expression of SLC7A6 mRNA CTD PMID:23153324 NCBI chr19:38,152,225...38,179,149
Ensembl chr19:38,162,515...38,179,149
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP [Mirex co-treated with Corticosterone] results in increased activity of TAT protein CTD PMID:2893471 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 increases expression EXP Mirex results in increased expression of TRIP13 mRNA CTD PMID:23153324 NCBI chr 1:31,967,980...32,012,923
Ensembl chr 1:31,967,978...32,012,919
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19783
    role 19728
      chemical role 19268
        environmental contaminant 18604
          persistent organic pollutant 15804
            mirex 50
Path 2
Term Annotations click to browse term
  CHEBI ontology 19783
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19588
                        carbon atom 19578
                          organic molecular entity 19578
                            heteroorganic entity 19208
                              organohalogen compound 17843
                                organochlorine compound 17633
                                  organochlorine pesticide 6296
                                    organochlorine insecticide 5547
                                      mirex 50
paths to the root