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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:M1
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Accession:CHEBI:34826 term browser browse the term
Definition:A carbamate ester that has formula C12H11Cl2NO4.
Synonyms:related_synonym: 2-(((3,5-Dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid;   Formula=C12H11Cl2NO4;   InChI=1S/C12H11Cl2NO4/c1-3-12(2,10(16)17)19-11(18)15-9-5-7(13)4-8(14)6-9/h3-6H,1H2,2H3,(H,15,18)(H,16,17);   InChIKey=KTXGWKXVQGCPAR-UHFFFAOYSA-N;   SMILES=CC(OC(=O)Nc1cc(Cl)cc(Cl)c1)(C=C)C(O)=O
 xref: CAS:119209-27-7;   KEGG:C14206
 xref_mesh: MESH:C101851


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M1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
decreases activity 		ISO
EXP 		2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and results in decreased activity of AR protein; 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid results in decreased activity of AR protein
2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and affects the activity of AR protein; 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and results in decreased activity of AR protein 		CTD PMID:10188192 PMID:11403899 PMID:11861974 PMID:16417039 PMID:16750840 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and results in increased activity of ESR1 protein CTD PMID:16750840 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and results in increased activity of ESR2 protein CTD PMID:16750840 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 multiple interactions ISO 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]; 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid inhibits the reaction [Dihydrotestosterone results in increased secretion of KLK3 protein] CTD PMID:35595151 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:103,539,527...103,543,586 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      atom 20860
        nonmetal atom 20766
          nitrogen atom 19595
            nitrogen molecular entity 19595
              organonitrogen compound 19403
                carbamic acid 17943
                  carbamate ester 7537
                    M1 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbon oxoacid 19155
                                    carbamic acid 17943
                                      carbamate ester 7537
                                        M1 4
paths to the root