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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:M1
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Accession:CHEBI:34826 term browser browse the term
Definition:A carbamate ester that has formula C12H11Cl2NO4.
Synonyms:related_synonym: 2-(((3,5-Dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid;   Formula=C12H11Cl2NO4;   InChI=1S/C12H11Cl2NO4/c1-3-12(2,10(16)17)19-11(18)15-9-5-7(13)4-8(14)6-9/h3-6H,1H2,2H3,(H,15,18)(H,16,17);   InChIKey=KTXGWKXVQGCPAR-UHFFFAOYSA-N;   SMILES=CC(OC(=O)Nc1cc(Cl)cc(Cl)c1)(C=C)C(O)=O
 xref: CAS:119209-27-7;   KEGG:C14206
 xref_mesh: MESH:C101851


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M1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
decreases activity		 ISO
EXP		 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and results in decreased activity of AR protein; 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid results in decreased activity of AR protein
2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and affects the activity of AR protein; 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and results in decreased activity of AR protein		 CTD PMID:10188192 PMID:11403899 PMID:11861974 PMID:16417039 PMID:16750840 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and results in increased activity of ESR1 protein CTD PMID:16750840 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and results in increased activity of ESR2 protein CTD PMID:16750840 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 multiple interactions ISO 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]; 2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid inhibits the reaction [Dihydrotestosterone results in increased secretion of KLK3 protein] CTD PMID:35595151 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    chemical entity 19919
      atom 19919
        nonmetal atom 19848
          nitrogen atom 19027
            nitrogen molecular entity 19027
              organonitrogen compound 18877
                carbamic acid 17601
                  carbamate ester 7511
                    M1 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    p-block element atom 19865
                      carbon group element atom 19804
                        carbon atom 19801
                          organic molecular entity 19801
                            heteroorganic entity 19558
                              organochalcogen compound 19317
                                organooxygen compound 19233
                                  carbon oxoacid 18695
                                    carbamic acid 17601
                                      carbamate ester 7511
                                        M1 4
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