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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:heptanal
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Accession:CHEBI:34787 term browser browse the term
Definition:An n-alkanal resulting from the oxidation of the alcoholic hydroxy group of heptan-1-ol to the corresponding aldehyde. An endogenous aldehyde coming from membrane lipid oxidation, it is found in the blood of lung cancer patients and has been regarded as a potential biomarker of lung cancer.
Synonyms:related_synonym: Formula=C7H14O;   InChI=1S/C7H14O/c1-2-3-4-5-6-7-8/h7H,2-6H2,1H3;   InChIKey=FXHGMKSSBGDXIY-UHFFFAOYSA-N;   SMILES=O=CCCCCCC;   aldehyde C-7;   enanthal;   enanthaldehyde;   enanthic aldehyde;   heptaldehyde;   heptanaldehyde;   heptyl aldehyde;   heptylaldehyde;   n-C6H13CHO;   n-heptaldehyde;   n-heptanal;   n-heptylaldehyde;   oenanthal;   oenanthaldehyde;   oenanthic aldehyde;   oenanthol
 xref: AGR:IND92060298;   CAS:111-71-7;   HMDB:HMDB0031475;   KEGG:C14390;   KNApSAcK:C00034880
 xref_mesh: MESH:C046204
 xref: PMID:13684163;   PMID:13802512;   PMID:15556514;   PMID:20120041;   PMID:22626821;   PMID:24401388;   PMID:24421258;   PMID:28292517;   PMID:28366212;   PMID:29526787;   Wikipedia:Heptanal


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heptanal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot9 acyl-CoA thioesterase 9 increases methylation ISO heptanal results in increased methylation of ACOT9 gene CTD PMID:30002397 NCBI chr  X:40,073,197...40,123,573
Ensembl chr  X:40,064,810...40,123,559 		JBrowse link
G Aire autoimmune regulator increases methylation ISO heptanal results in increased methylation of AIRE gene CTD PMID:30002397 NCBI chr20:10,636,058...10,651,060
Ensembl chr20:10,636,123...10,651,060 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B affects reduction
increases reduction		 ISO AKR1B1 protein affects the reduction of heptanal
AKR1B1 protein results in increased reduction of heptanal		 CTD PMID:9890881 PMID:11306073 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G B3galt4 Beta-1,3-galactosyltransferase 4 decreases expression ISO heptanal results in decreased expression of B3GALT4 mRNA CTD PMID:25014914 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315 		JBrowse link
G Bmp10 bone morphogenetic protein 10 increases methylation ISO heptanal results in increased methylation of BMP10 gene CTD PMID:30002397 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Ca9 carbonic anhydrase 9 decreases expression ISO heptanal results in decreased expression of CA9 mRNA CTD PMID:25014914 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Ccna1 cyclin A1 increases methylation ISO heptanal results in increased methylation of CCNA1 gene CTD PMID:30002397 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccnb1ip1 cyclin B1 interacting protein 1 increases methylation ISO heptanal results in increased methylation of CCNB1IP1 gene CTD PMID:30002397 NCBI chr15:24,014,905...24,031,357
Ensembl chr15:24,014,908...24,028,475 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 increases expression ISO heptanal results in increased expression of CEMIP mRNA CTD PMID:25014914 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Cep85 centrosomal protein 85 increases methylation ISO heptanal results in increased methylation of CEP85 gene CTD PMID:30002397 NCBI chr 5:146,356,575...146,404,155
Ensembl chr 5:146,356,576...146,404,060 		JBrowse link
G Chd3 chromodomain helicase DNA binding protein 3 increases methylation ISO heptanal results in increased methylation of CHD3 gene CTD PMID:30002397 NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 increases methylation ISO heptanal results in increased methylation of COX17 gene CTD PMID:30002397 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO heptanal results in increased expression of CYP1A1 mRNA CTD PMID:25014914 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Dnaaf2 dynein, axonemal, assembly factor 2 increases methylation ISO heptanal results in increased methylation of DNAAF2 gene CTD PMID:30002397 NCBI chr 6:87,661,101...87,670,267
Ensembl chr 6:87,660,821...87,670,199 		JBrowse link
G Gna15 G protein subunit alpha 15 increases response to substance
multiple interactions		 ISO GNA15 protein results in increased susceptibility to heptanal
[GNA15 protein results in increased susceptibility to heptanal] which results in increased activity of OLFR2 protein		 CTD PMID:9875846 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508 		JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases methylation ISO heptanal results in increased methylation of HSD17B11 gene CTD PMID:30002397 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161 		JBrowse link
G Jchain joining chain of multimeric IgA and IgM increases methylation ISO heptanal results in increased methylation of JCHAIN gene CTD PMID:30002397 NCBI chr14:19,538,560...19,546,384
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Kcnf1 potassium voltage-gated channel modifier subfamily F member 1 increases methylation ISO heptanal results in increased methylation of KCNF1 gene CTD PMID:30002397 NCBI chr 6:39,962,301...39,964,979
Ensembl chr 6:39,962,307...39,964,979 		JBrowse link
G Kif7 kinesin family member 7 increases methylation ISO heptanal results in increased methylation of KIF7 gene CTD PMID:30002397 NCBI chr 1:133,639,487...133,658,539
Ensembl chr 1:133,640,065...133,658,576 		JBrowse link
G Lhfpl3 LHFPL tetraspan subfamily member 3 increases methylation ISO heptanal results in increased methylation of LHFPL3 gene CTD PMID:30002397
G LOC100911842 uncharacterized LOC100911842 decreases methylation ISO heptanal results in decreased methylation of C9ORF57 gene CTD PMID:30002397 NCBI chr 1:219,079,683...219,084,806
Ensembl chr 1:219,079,683...219,084,806 		JBrowse link
G Lrrc74a leucine rich repeat containing 74A increases methylation ISO heptanal results in increased methylation of LRRC74A gene CTD PMID:30002397 NCBI chr 6:106,386,276...106,417,112
Ensembl chr 6:106,386,347...106,416,193 		JBrowse link
G Mfn1 mitofusin 1 increases methylation ISO heptanal results in increased methylation of MFN1 gene CTD PMID:30002397 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mir128-1 microRNA 128-1 increases methylation ISO heptanal results in increased methylation of MIR128-1 gene CTD PMID:30002397 NCBI chr13:39,699,449...39,699,530
Ensembl chr13:39,699,449...39,699,530 		JBrowse link
G Mrps18a mitochondrial ribosomal protein S18A increases methylation ISO heptanal results in increased methylation of MRPS18A gene CTD PMID:30002397 NCBI chr 9:14,853,322...14,869,819
Ensembl chr 9:14,853,291...14,869,835 		JBrowse link
G Myt1 myelin transcription factor 1 increases methylation ISO heptanal results in increased methylation of MYT1 gene CTD PMID:30002397 NCBI chr 3:168,890,466...168,950,341
Ensembl chr 3:168,886,089...168,950,341 		JBrowse link
G Nfxl1 nuclear transcription factor, X-box binding-like 1 increases methylation ISO heptanal results in increased methylation of NFXL1 gene CTD PMID:30002397 NCBI chr14:35,626,086...35,667,505
Ensembl chr14:35,626,066...35,667,498 		JBrowse link
G Nmbr neuromedin B receptor increases methylation ISO heptanal results in increased methylation of NMBR gene CTD PMID:30002397 NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex increases methylation ISO heptanal results in increased methylation of NUF2 gene CTD PMID:30002397 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766 		JBrowse link
G Olr1597 olfactory receptor 1597 increases methylation ISO heptanal results in increased methylation of OR10Z1 gene CTD PMID:30002397 NCBI chr13:86,281,535...86,282,476
Ensembl chr13:86,278,626...86,283,642 		JBrowse link
G Olr226 olfactory receptor 226 multiple interactions
increases activity		 ISO [GNA15 protein results in increased susceptibility to heptanal] which results in increased activity of OLFR2 protein
heptanal results in increased activity of OLFR2 protein		 CTD PMID:9875846 NCBI chr 1:160,827,258...160,828,241
Ensembl chr 1:160,793,997...160,831,557 		JBrowse link
G Pcdha10 protocadherin alpha 10 increases methylation ISO heptanal results in increased methylation of PCDHA10 gene CTD PMID:30002397
G Pcdha9 protocadherin alpha 9 increases methylation ISO heptanal results in increased methylation of PCDHA9 gene CTD PMID:30002397
G Pde4a phosphodiesterase 4A increases methylation ISO heptanal results in increased methylation of PDE4A gene CTD PMID:30002397 NCBI chr 8:19,706,649...19,751,937
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Pex2 peroxisomal biogenesis factor 2 increases methylation ISO heptanal results in increased methylation of PEX2 gene CTD PMID:30002397 NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 increases methylation ISO heptanal results in increased methylation of PHACTR1 gene CTD PMID:30002397 NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831 		JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha increases methylation ISO heptanal results in increased methylation of PIK3C2A gene CTD PMID:30002397 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472 		JBrowse link
G Plppr5 phospholipid phosphatase related 5 increases methylation ISO heptanal results in increased methylation of PLPPR5 gene CTD PMID:30002397 NCBI chr 2:205,525,466...205,737,892
Ensembl chr 2:205,458,176...205,717,599 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta increases methylation ISO heptanal results in increased methylation of PRKACB gene CTD PMID:30002397 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Reg1a regenerating family member 1 alpha increases methylation ISO heptanal results in increased methylation of REG1A gene CTD PMID:30002397 NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570 		JBrowse link
G Sbsn suprabasin increases expression ISO heptanal results in increased expression of SBSN mRNA CTD PMID:25014914 NCBI chr 1:85,979,477...86,006,034
Ensembl chr 1:86,001,567...86,006,034 		JBrowse link
G Slc39a5 solute carrier family 39 member 5 decreases expression ISO heptanal results in decreased expression of SLC39A5 mRNA CTD PMID:25014914 NCBI chr 7:822,873...830,865
Ensembl chr 7:824,818...830,242 		JBrowse link
G Slk STE20-like kinase increases methylation ISO heptanal results in increased methylation of SLK gene CTD PMID:30002397 NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530 		JBrowse link
G Snca synuclein alpha increases methylation ISO heptanal results in increased methylation of SNCA gene CTD PMID:30002397 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Spink4 serine peptidase inhibitor, Kazal type 4 increases methylation ISO heptanal results in increased methylation of SPINK4 gene CTD PMID:30002397 NCBI chr 5:56,053,104...56,065,029
Ensembl chr 5:55,981,624...56,064,795 		JBrowse link
G Stpg4 sperm-tail PG-rich repeat containing 4 increases methylation ISO heptanal results in increased methylation of STPG4 gene CTD PMID:30002397 NCBI chr 6:7,108,827...7,158,519
Ensembl chr 6:7,108,869...7,151,390 		JBrowse link
G Tdrkh tudor and KH domain containing increases methylation ISO heptanal results in increased methylation of TDRKH gene CTD PMID:30002397 NCBI chr 2:182,049,175...182,071,516
Ensembl chr 2:182,049,215...182,070,755 		JBrowse link
G Thumpd3 THUMP domain containing 3 increases methylation ISO heptanal results in increased methylation of THUMPD3 gene CTD PMID:30002397 NCBI chr 4:146,185,422...146,209,802
Ensembl chr 4:146,185,503...146,211,246 		JBrowse link
G Trim27 tripartite motif-containing 27 increases methylation ISO heptanal results in increased methylation of TRIM27 gene CTD PMID:30002397 NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643 		JBrowse link
G Ubxn4 UBX domain protein 4 increases methylation ISO heptanal results in increased methylation of UBXN4 gene CTD PMID:30002397 NCBI chr13:39,740,077...39,772,347
Ensembl chr13:39,740,107...39,772,491 		JBrowse link
G Wdr75 WD repeat domain 75 increases methylation ISO heptanal results in increased methylation of WDR75 gene CTD PMID:30002397 NCBI chr 9:47,903,166...47,933,399
Ensembl chr 9:47,903,200...47,933,399 		JBrowse link
G Zfhx2 zinc finger homeobox 2 increases methylation ISO heptanal results in increased methylation of ZFHX2 gene CTD PMID:30002397 NCBI chr15:28,533,155...28,565,667
Ensembl chr15:28,533,156...28,565,128 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20059
    role 20009
      application 19747
        indicator 8700
          biomarker 6483
            heptanal 52
Path 2
Term Annotations click to browse term
  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19873
                          organic molecular entity 19873
                            organic group 18943
                              organic divalent group 18928
                                organodiyl group 18928
                                  carbonyl group 18877
                                    carbonyl compound 18877
                                      carboxylic acid 18565
                                        carboacyl group 17658
                                          univalent carboacyl group 17658
                                            formyl group 8805
                                              aldehyde 8805
                                                aliphatic aldehyde 2147
                                                  fatty aldehyde 2135
                                                    saturated fatty aldehyde 1427
                                                      heptanal 52
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