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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:flumethasone
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Accession:CHEBI:34764 term browser browse the term
Definition:A glucocorticoid that has formula C22H28F2O5.
Synonyms:related_synonym: 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione;   Formula=C22H28F2O5;   InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1;   InChIKey=WXURHACBFYSXBI-GQKYHHCASA-N;   SMILES=[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C;   flumetasona;   flumetasone;   flumetasonum
 xref: Beilstein:5645455;   CAS:2135-17-3;   Drug_Central:4548;   KEGG:C14479;   KEGG:D04208
 xref_mesh: MESH:D005443
 xref: Patent:GB902292;   Patent:US3499016;   Wikipedia:Flumethasone


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flumethasone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases activity ISO Flumethasone results in increased activity of NR3C1 protein CTD PMID:15362971 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
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G Nr3c2 nuclear receptor subfamily 3, group C, member 2 increases activity ISO Flumethasone results in increased activity of NR3C2 protein CTD PMID:15362971 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19783
    role 19728
      application 19419
        anti-inflammatory agent 15763
          anti-inflammatory drug 13625
            flumethasone 2
              flumethasone pivalate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19783
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19588
                        carbon atom 19578
                          organic molecular entity 19578
                            organic group 18606
                              organic divalent group 18597
                                organodiyl group 18597
                                  carbonyl group 18510
                                    carbonyl compound 18510
                                      ketone 16828
                                        oxyketone 8663
                                          alpha-oxyketone 8663
                                            alpha-hydroxy ketone 8663
                                              primary alpha-hydroxy ketone 7541
                                                flumethasone 2
                                                  flumethasone pivalate 0
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