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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:flumethasone
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Accession:CHEBI:34764 term browser browse the term
Definition:A glucocorticoid that has formula C22H28F2O5.
Synonyms:related_synonym: 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione;   Formula=C22H28F2O5;   InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1;   InChIKey=WXURHACBFYSXBI-GQKYHHCASA-N;   SMILES=[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C;   flumetasona;   flumetasone;   flumetasonum
 xref: Beilstein:5645455;   CAS:2135-17-3;   Drug_Central:4548;   KEGG:C14479;   KEGG:D04208
 xref_mesh: MESH:D005443
 xref: Patent:GB902292;   Patent:US3499016;   Wikipedia:Flumethasone


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flumethasone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases activity ISO Flumethasone results in increased activity of NR3C1 protein CTD PMID:15362971 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 increases activity ISO Flumethasone results in increased activity of NR3C2 protein CTD PMID:15362971 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19751
    role 19724
      application 19557
        anti-inflammatory agent 16470
          anti-inflammatory drug 14927
            flumethasone 2
              flumethasone pivalate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19751
    subatomic particle 19749
      composite particle 19749
        hadron 19749
          baryon 19749
            nucleon 19749
              atomic nucleus 19749
                atom 19749
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19644
                        carbon atom 19640
                          organic molecular entity 19640
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18799
                                    carbonyl compound 18799
                                      ketone 17108
                                        oxyketone 8796
                                          alpha-oxyketone 8796
                                            alpha-hydroxy ketone 8796
                                              primary alpha-hydroxy ketone 7674
                                                flumethasone 2
                                                  flumethasone pivalate 0
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