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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:34725 term browser browse the term
Definition:An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory.
Synonyms:exact_synonym: (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene
 related_synonym: Formula=C16H15N;   InChI=1S/C16H15N/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16/h2-9,15,17H,10H2,1H3/t15-,16+/m1/s1;   InChIKey=LBOJYSIDWZQNJS-CVEARBPZSA-N;   MK 801;   MK801;   SMILES=[H][C@]12CC3=C(C=CC=C3)[C@](C)(N1)C1=C2C=CC=C1;   dizocilpina;   dizocilpinum
 xref: CAS:77086-21-6;   Chemspider:156718;   KEGG:C13737;   LINCS:LSM-5688;   PDBeChem:BMK;   PMID:28232581;   PMID:29489358;   PMID:29670280;   PMID:30772438;   PMID:31177060;   PMID:32105720;   PMID:32219769;   PMID:32289529;   PMID:32324160;   PMID:32641944;   PMID:32760846;   PMID:32808583;   PMID:32892308;   PMID:32956214;   PMID:32973585;   PMID:33187817;   PMID:33249825;   PMID:33324181;   PMID:33404734;   PMID:33442771;   PMID:33639267;   PMID:33656787;   PMID:33723767;   PMID:33809889;   PMID:33882624;   PMID:33891976;   PMID:33945878;   PMID:33974921;   PMID:34054433;   PMID:34098454;   PMID:34119597;   PMID:34177484;   Wikipedia:Dizocilpine
 cyclic_relationship: is_conjugate_base_of CHEBI:176787

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dizocilpine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 affects binding EXP Dizocilpine binds to Drd2 protein RGD PMID:15852061 RGD:1581406 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
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  CHEBI ontology 20056
    role 20008
      application 19745
        pharmaceutical 19618
          drug 19618
            anaesthetic 9332
              dizocilpine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    main group molecular entity 19956
                      s-block molecular entity 19752
                        hydrogen molecular entity 19745
                          hydrides 19114
                            inorganic hydride 17882
                              pnictogen hydride 17865
                                nitrogen hydride 17754
                                  azane 17503
                                    ammonia 17502
                                      organic amino compound 17502
                                        secondary amino compound 6679
                                          dizocilpine 1
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