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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:34725 term browser browse the term
Definition:An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory.
Synonyms:exact_synonym: (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene
 related_synonym: Formula=C16H15N;   InChI=1S/C16H15N/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16/h2-9,15,17H,10H2,1H3/t15-,16+/m1/s1;   InChIKey=LBOJYSIDWZQNJS-CVEARBPZSA-N;   MK 801;   MK801;   SMILES=[H][C@]12CC3=C(C=CC=C3)[C@](C)(N1)C1=C2C=CC=C1;   dizocilpina;   dizocilpinum
 xref: CAS:77086-21-6;   Chemspider:156718;   KEGG:C13737;   LINCS:LSM-5688;   PDBeChem:BMK;   PMID:28232581;   PMID:29489358;   PMID:29670280;   PMID:30772438;   PMID:31177060;   PMID:32105720;   PMID:32219769;   PMID:32289529;   PMID:32324160;   PMID:32641944;   PMID:32760846;   PMID:32808583;   PMID:32892308;   PMID:32956214;   PMID:32973585;   PMID:33187817;   PMID:33249825;   PMID:33324181;   PMID:33404734;   PMID:33442771;   PMID:33639267;   PMID:33656787;   PMID:33723767;   PMID:33809889;   PMID:33882624;   PMID:33891976;   PMID:33945878;   PMID:33974921;   PMID:34054433;   PMID:34098454;   PMID:34119597;   PMID:34177484;   Wikipedia:Dizocilpine
 cyclic_relationship: is_conjugate_base_of CHEBI:176787

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dizocilpine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 affects binding EXP Dizocilpine binds to Drd2 protein RGD PMID:15852061 RGD:1581406 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
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  CHEBI ontology 19810
    role 19759
      application 19468
        pharmaceutical 19316
          drug 19316
            anaesthetic 5980
              dizocilpine 1
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  CHEBI ontology 19810
    subatomic particle 19809
      composite particle 19809
        hadron 19809
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19706
                    main group molecular entity 19706
                      s-block molecular entity 19490
                        hydrogen molecular entity 19485
                          hydrides 18845
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  azane 17280
                                    ammonia 17279
                                      organic amino compound 17279
                                        secondary amino compound 6587
                                          dizocilpine 1
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