CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1-chloro-2,4-dinitrobenzene
Accession: CHEBI:34718
browse the term
Definition: A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Synonyms: related_synonym: 1,3-Dinitro-4-chlorobenzene; 1-Chloro-2,4-dinitrobenzol; 2,4-Dinitro-1-chlorobenzene; 2,4-Dinitrochlorobenzene; 2,4-Dinitrophenyl chloride; 4-Chloro-1,3-dinitrobenzene; 6-Chloro-1,3-dinitrobenzene; Cdnb; Chlorodinitrobenzene; ClDNB; DNPCl; Dinitrochlorobenzene; Dncb; Formula=C6H3ClN2O4; InChI=1S/C6H3ClN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H; InChIKey=VYZAHLCBVHPDDF-UHFFFAOYSA-N; SMILES=[O-][N+](=O)c1ccc(Cl)c(c1)[N+]([O-])=O
xref: Beilstein:613161; CAS:97-00-7; Gmelin:28481; KEGG:C14397
xref_mesh: MESH:D004137
xref: PMID:1155304; PMID:12176098; PMID:1447476; PMID:15009707; PMID:15588915; PMID:1640019; PMID:18316151; PMID:18775882; PMID:19171927; PMID:1982449; PMID:25515858; PMID:29079364; PMID:3180787; PMID:6446435; PMID:7059096; PMID:7179722; PMID:7994925; Reaxys:613161; Wikipedia:2\,4-Dinitrochlorobenzene
G
Aars1
alanyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to AARS1 protein
CTD
PMID:32991956
NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
G
Abca6
ATP binding cassette subfamily A member 6
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ABCA6 mRNA
CTD
PMID:17374397
NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530
G
Abcc2
ATP binding cassette subfamily C member 2
decreases response to substance
ISO
ABCC2 protein results in decreased susceptibility to Dinitrochlorobenzene
CTD
PMID:26049102
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
G
Abhd10
abhydrolase domain containing 10, depalmitoylase
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ABHD10 mRNA
CTD
PMID:17374397
NCBI chr11:55,081,273...55,095,044
Ensembl chr11:55,081,049...55,107,866
G
Abhd11
abhydrolase domain containing 11
affects binding
ISO
Dinitrochlorobenzene binds to ABHD11 protein
CTD
PMID:32991956
NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398
G
Acat2
acetyl-CoA acetyltransferase 2
affects binding
ISO
Dinitrochlorobenzene binds to ACAT2 protein
CTD
PMID:32991956
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
G
Acly
ATP citrate lyase
affects binding
ISO
Dinitrochlorobenzene binds to ACLY protein
CTD
PMID:32991956
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
G
Acod1
aconitate decarboxylase 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of ACOD1 mRNA
CTD
PMID:22302311
NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529
G
Acox2
acyl-CoA oxidase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ACOX2 mRNA
CTD
PMID:16314067
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
G
Acp1
acid phosphatase 1
affects binding
ISO
Dinitrochlorobenzene binds to ACP1 protein
CTD
PMID:32991956
NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021
G
Acsl1
acyl-CoA synthetase long-chain family member 1
affects binding
ISO
Dinitrochlorobenzene binds to ACSL1 protein
CTD
PMID:32991956
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
G
Acsl4
acyl-CoA synthetase long-chain family member 4
affects binding
ISO
Dinitrochlorobenzene binds to ACSL4 protein
CTD
PMID:32991956
NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
G
Actb
actin, beta
increases metabolic processing affects binding
ISO
Dinitrochlorobenzene results in increased metabolism of ACTB protein Dinitrochlorobenzene binds to ACTB protein
CTD
PMID:29267982 PMID:32991956
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
G
Adamts15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ADAMTS15 mRNA
CTD
PMID:19647056
NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249
G
Adm
adrenomedullin
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ADM mRNA
CTD
PMID:25236440
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
G
Adnp2
ADNP homeobox 2
affects binding
ISO
Dinitrochlorobenzene binds to ADNP2 protein
CTD
PMID:32991956
NCBI chr18:73,571,870...73,597,088
Ensembl chr18:73,571,936...73,628,484
G
Adora2b
adenosine A2B receptor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ADORA2B mRNA
CTD
PMID:16314067
NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
G
Adsl
adenylosuccinate lyase
affects binding
ISO
Dinitrochlorobenzene binds to ADSL protein
CTD
PMID:32991956
NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760
G
Afg2b
AFG2 AAA ATPase homolog B
affects binding
ISO
Dinitrochlorobenzene binds to AFG2B protein
CTD
PMID:32991956
NCBI chr 3:109,694,739...109,708,356
Ensembl chr 3:109,694,757...109,707,757
G
Aicda
activation-induced cytidine deaminase
affects expression
ISO
Dinitrochlorobenzene affects the expression of AICDA mRNA
CTD
PMID:22302311
NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
G
Aifm1
apoptosis inducing factor, mitochondria associated 1
affects binding
ISO
Dinitrochlorobenzene binds to AIFM1 protein
CTD
PMID:32991956
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
G
Akap13
A-kinase anchoring protein 13
affects binding
ISO
Dinitrochlorobenzene binds to AKAP13 protein
CTD
PMID:32991956
NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
G
Akr1b1
aldo-keto reductase family 1 member B1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of AKR1B1 mRNA
CTD
PMID:20566472
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
G
Akr1b10
aldo-keto reductase family 1 member B10
increases expression
ISO
Dinitrochlorobenzene results in increased expression of AKR1B10 mRNA
CTD
PMID:20566472
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
G
Akr1c1
aldo-keto reductase family 1, member C1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of AKR1C1 mRNA
CTD
PMID:20566472
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
G
Akr1c2
aldo-keto reductase family 1, member C2
increases activity increases expression
ISO
Dinitrochlorobenzene results in increased activity of AKR1C2 promoter Dinitrochlorobenzene results in increased expression of AKR1C2 mRNA
CTD
PMID:20491607 PMID:20713136 PMID:21195160
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
G
Akr1c3
aldo-keto reductase family 1, member C3
increases expression affects expression
ISO
Dinitrochlorobenzene results in increased expression of AKR1C3 mRNA Dinitrochlorobenzene affects the expression of AKR1C18 mRNA
CTD
PMID:20566472 PMID:22302311
NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
G
Akt2
AKT serine/threonine kinase 2
affects binding
ISO
Dinitrochlorobenzene binds to AKT2 protein
CTD
PMID:32991956
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
G
Alb
albumin
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of ALB protein
CTD
PMID:29267982
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
Ankrd12
ankyrin repeat domain 12
affects binding
ISO
Dinitrochlorobenzene binds to ANKRD12 protein
CTD
PMID:32991956
NCBI chr 9:105,583,273...105,687,957
Ensembl chr 9:105,584,065...105,687,911
G
Ankrd2
ankyrin repeat domain 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ANKRD2 mRNA
CTD
PMID:19647056
NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566
G
Ankrd35
ankyrin repeat domain 35
affects binding
ISO
Dinitrochlorobenzene binds to ANKRD35 protein
CTD
PMID:32991956
NCBI chr 2:184,207,076...184,227,063
Ensembl chr 2:184,207,071...184,227,063
G
Ankrd37
ankyrin repeat domain 37
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ANKRD37 mRNA
CTD
PMID:25236440
NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963
G
Anxa1
annexin A1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ANXA1 mRNA
CTD
PMID:16314067
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
G
Anxa2
annexin A2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ANXA2 mRNA
CTD
PMID:16314067
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
G
Anxa3
annexin A3
affects binding
ISO
Dinitrochlorobenzene binds to ANXA3 protein
CTD
PMID:32991956
NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
G
Ap1b1
adaptor related protein complex 1 subunit beta 1
affects binding
ISO
Dinitrochlorobenzene binds to AP1B1 protein
CTD
PMID:32991956
NCBI chr14:79,879,482...79,930,778
Ensembl chr14:79,879,533...79,930,778
G
Ap2a1
adaptor related protein complex 2 subunit alpha 1
affects binding
ISO
Dinitrochlorobenzene binds to AP2A1 protein
CTD
PMID:32991956
NCBI chr 1:95,384,306...95,414,170
Ensembl chr 1:95,384,309...95,414,147
G
Ap2b1
adaptor related protein complex 2 subunit beta 1
affects binding
ISO
Dinitrochlorobenzene binds to AP2B1 protein
CTD
PMID:32991956
NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
G
Ap3d1
adaptor related protein complex 3 subunit delta 1
affects binding
ISO
Dinitrochlorobenzene binds to AP3D1 protein
CTD
PMID:32991956
NCBI chr 7:8,970,249...9,005,651
Ensembl chr 7:8,970,291...9,005,643
G
Aqr
aquarius intron-binding spliceosomal factor
affects binding
ISO
Dinitrochlorobenzene binds to AQR protein
CTD
PMID:32991956
NCBI chr 3:100,874,987...100,945,026
Ensembl chr 3:100,874,987...100,945,044
G
Arf5
ADP-ribosylation factor 5
affects binding
ISO
Dinitrochlorobenzene binds to ARF5 protein
CTD
PMID:32991956
NCBI chr 4:57,038,521...57,041,447
Ensembl chr 4:57,038,521...57,041,441
G
Arg2
arginase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ARG2 mRNA
CTD
PMID:16314067
NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
G
Arl4c
ADP ribosylation factor like GTPase 4C
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ARL4C mRNA
CTD
PMID:17374397
NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
G
Arpc2
actin related protein 2/3 complex, subunit 2
affects binding
ISO
Dinitrochlorobenzene binds to ARPC2 protein
CTD
PMID:32991956
NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
G
Arpc3
actin related protein 2/3 complex, subunit 3
affects binding
ISO
Dinitrochlorobenzene binds to ARPC3 protein
CTD
PMID:32991956
NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651
G
Asns
asparagine synthetase (glutamine-hydrolyzing)
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ASNS mRNA
CTD
PMID:18242016
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
G
Ass1
argininosuccinate synthase 1
affects binding
ISO
Dinitrochlorobenzene binds to ASS1 protein
CTD
PMID:32991956
NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
G
Atf3
activating transcription factor 3
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of ATF3 mRNA KN 62 inhibits the reaction [Dinitrochlorobenzene results in increased expression of ATF3 mRNA]
CTD
PMID:23999411 PMID:27965148 PMID:28941582
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
G
Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
affects binding
ISO
Dinitrochlorobenzene binds to ATIC protein
CTD
PMID:32991956
NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
G
Atp5f1a
ATP synthase F1 subunit alpha
affects binding
ISO
Dinitrochlorobenzene binds to ATP5F1A protein
CTD
PMID:32991956
NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
G
Azin1
antizyme inhibitor 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of AZIN1 mRNA
CTD
PMID:17374397
NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
G
B2m
beta-2 microglobulin
affects expression
ISO
Dinitrochlorobenzene affects the expression of B2M mRNA
CTD
PMID:28219650
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
G
Bach1
BTB domain and CNC homolog 1
multiple interactions
ISO
BACH1 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]
CTD
PMID:26244607
NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
G
Bambi
BMP and activin membrane-bound inhibitor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of BAMBI mRNA
CTD
PMID:20146380
NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
G
Bcl2
BCL2, apoptosis regulator
multiple interactions affects expression
ISO
NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of BCL2 mRNA] Dinitrochlorobenzene affects the expression of BCL2 mRNA
CTD
PMID:28219650
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Bclaf1
BCL2-associated transcription factor 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of BCLAF1 mRNA
CTD
PMID:17374397
NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
G
Bdnf
brain-derived neurotrophic factor
multiple interactions
EXP
Dinitrochlorobenzene inhibits the reaction [BDNF protein results in decreased susceptibility to 3-nitropropionic acid]
CTD
PMID:19428112
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
G
Bmp6
bone morphogenetic protein 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of BMP6 mRNA
CTD
PMID:17374397
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
G
Bspry
B-box and SPRY domain containing
increases expression
ISO
Dinitrochlorobenzene results in increased expression of BSPRY mRNA
CTD
PMID:18242016
NCBI chr 5:75,927,397...75,949,585
Ensembl chr 5:75,927,405...75,949,583
G
Bst2
bone marrow stromal cell antigen 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of BST2 mRNA
CTD
PMID:19647056
NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
G
Btg1
BTG anti-proliferation factor 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of BTG1 mRNA
CTD
PMID:17374397
NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
G
Bub1
BUB1 mitotic checkpoint serine/threonine kinase
decreases expression increases expression
ISO
Dinitrochlorobenzene results in decreased expression of BUB1 mRNA Dinitrochlorobenzene results in increased expression of BUB1 mRNA
CTD
PMID:17374397 PMID:21404309
NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
G
Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
increases expression
ISO
Dinitrochlorobenzene results in increased expression of BUB1B mRNA
CTD
PMID:21404309
NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
G
C3
complement C3
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of C3 protein
CTD
PMID:29267982
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
G
Calca
calcitonin-related polypeptide alpha
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CALCA mRNA
CTD
PMID:20146380
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
G
Calcrl
calcitonin receptor like receptor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CALCRL mRNA
CTD
PMID:17374397
NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910
G
Canx
calnexin
affects binding
ISO
Dinitrochlorobenzene binds to CANX protein
CTD
PMID:32991956
NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
G
Capza2
capping actin protein of muscle Z-line subunit alpha 2
affects binding
ISO
Dinitrochlorobenzene binds to CAPZA2 protein
CTD
PMID:32991956
NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864
G
Car2
carbonic anhydrase 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CA2 mRNA
CTD
PMID:17374397
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
G
Casp1
caspase 1
increases expression increases phosphorylation increases activity multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of CASP1 mRNA Dinitrochlorobenzene results in increased phosphorylation of CASP1 protein Dinitrochlorobenzene results in increased activity of CASP1 protein Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein]
CTD
PMID:28219650 PMID:30842373 PMID:31276767
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
G
Casp3
caspase 3
decreases expression increases expression multiple interactions
ISO
Dinitrochlorobenzene results in decreased expression of CASP3 mRNA Dinitrochlorobenzene results in increased expression of CASP3 mRNA; Dinitrochlorobenzene results in increased expression of CASP3 protein sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of CASP3 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of CASP3 protein]
CTD
PMID:28219650 PMID:34651546
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Casp8ap2
caspase 8 associated protein 2
affects binding
ISO
Dinitrochlorobenzene binds to CASP8AP2 protein
CTD
PMID:32991956
NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275
G
Casp9
caspase 9
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CASP9 mRNA
CTD
PMID:28219650
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
G
Cat
catalase
increases expression multiple interactions decreases expression
ISO
Dinitrochlorobenzene results in increased expression of CAT mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of CAT mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of CAT protein]
CTD
PMID:20566472 PMID:28219650 PMID:34651546
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Ccl11
C-C motif chemokine ligand 11
multiple interactions increases expression
ISO
Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL11 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL11 mRNA]
CTD
PMID:23133493
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
G
Ccl12
C-C motif chemokine ligand 12
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CCL12 mRNA
CTD
PMID:19647056
NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
G
Ccl17
C-C motif chemokine ligand 17
multiple interactions increases expression
ISO
diflorasone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL17 protein]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL17 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL17 protein] Dinitrochlorobenzene results in increased expression of CCL17 mRNA; Dinitrochlorobenzene results in increased expression of CCL17 protein
CTD
PMID:15491423 PMID:21404309 PMID:23454147
NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
G
Ccl19
C-C motif chemokine ligand 19
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CCL19 mRNA
CTD
PMID:21404309
NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
G
Ccl2
C-C motif chemokine ligand 2
decreases expression decreases secretion increases secretion increases expression multiple interactions
ISO
Dinitrochlorobenzene results in decreased expression of CCL2 mRNA Dinitrochlorobenzene results in decreased secretion of CCL2 protein Dinitrochlorobenzene results in increased secretion of CCL2 protein Dinitrochlorobenzene results in increased expression of CCL2 mRNA Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL2 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL2 mRNA]
CTD
PMID:15585374 PMID:17374397 PMID:19647056 PMID:20488241 PMID:20713136 PMID:21404309 PMID:22245253 PMID:23133493 More...
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
G
Ccl20
C-C motif chemokine ligand 20
affects expression
ISO
Dinitrochlorobenzene affects the expression of CCL20 mRNA
CTD
PMID:28219650
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
G
Ccl22
C-C motif chemokine ligand 22
affects expression
ISO
Dinitrochlorobenzene affects the expression of CCL22 mRNA
CTD
PMID:28219650
NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
G
Ccl3
C-C motif chemokine ligand 3
increases expression affects expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of CCL3 mRNA Dinitrochlorobenzene affects the expression of CCL3 mRNA NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL3 mRNA]
CTD
PMID:15585374 PMID:19647056 PMID:20146380 PMID:28219650
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
G
Ccl4
C-C motif chemokine ligand 4
increases expression increases secretion
ISO
Dinitrochlorobenzene results in increased expression of CCL4 mRNA Dinitrochlorobenzene results in increased secretion of CCL4 protein Dinitrochlorobenzene results in increased expression of CCL4 mRNA; Dinitrochlorobenzene results in increased expression of CCL4 protein
CTD
PMID:15585374 PMID:16314067 PMID:18353026 PMID:19647056 PMID:20146380 PMID:28219650 More...
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
G
Ccl5
C-C motif chemokine ligand 5
multiple interactions increases expression increases secretion decreases expression
ISO
diflorasone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL5 protein] Dinitrochlorobenzene results in increased secretion of CCL5 protein Dinitrochlorobenzene results in decreased expression of CCL5 mRNA
CTD
PMID:15491423 PMID:20488241 PMID:21404309 PMID:28219650
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
G
Ccl7
C-C motif chemokine ligand 7
increases expression
EXP ISO
Dinitrochlorobenzene results in increased expression of CCL7 mRNA
CTD
PMID:19647056 PMID:21404309 PMID:21893156
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
G
Ccl9
C-C motif chemokine ligand 9
increases expression affects expression
ISO
Dinitrochlorobenzene results in increased expression of CCL6 mRNA Dinitrochlorobenzene affects the expression of CCL6 mRNA
CTD
PMID:19647056 PMID:21404309 PMID:22302311
NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
G
Ccna2
cyclin A2
affects expression increases expression
ISO
Dinitrochlorobenzene affects the expression of CCNA2 mRNA Dinitrochlorobenzene results in increased expression of CCNA2 mRNA
CTD
PMID:21404309 PMID:22302311
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
G
Ccnb1
cyclin B1
affects expression
ISO
Dinitrochlorobenzene affects the expression of CCNB1 mRNA
CTD
PMID:22302311
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
G
Ccnb2
cyclin B2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CCNB2 mRNA
CTD
PMID:21404309
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
G
Ccne1
cyclin E1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CCNE1 mRNA
CTD
PMID:21404309
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
G
Ccne2
cyclin E2
affects expression
ISO
Dinitrochlorobenzene affects the expression of CCNE2 mRNA
CTD
PMID:22302311
NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
G
Ccnf
cyclin F
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CCNF mRNA
CTD
PMID:18242016
NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
G
Ccr1
C-C motif chemokine receptor 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CCR1 mRNA
CTD
PMID:19647056
NCBI chr 8:123,556,286...123,561,841
G
Ccr2
C-C motif chemokine receptor 2
decreases expression increases expression
ISO
Dinitrochlorobenzene results in decreased expression of CCR2 mRNA Dinitrochlorobenzene results in increased expression of CCR2 mRNA
CTD
PMID:17374397 PMID:19371601 PMID:19647056 PMID:20713136
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
G
Ccr3
C-C motif chemokine receptor 3
multiple interactions increases expression
ISO
Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCR3 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCR3 mRNA]
CTD
PMID:23133493
NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
G
Ccr4
C-C motif chemokine receptor 4
affects expression
ISO
Dinitrochlorobenzene affects the expression of CCR4 mRNA
CTD
PMID:22302311
NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056
G
Ccr5
C-C motif chemokine receptor 5
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CCR5 mRNA
CTD
PMID:20713136
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
G
Ccr6
C-C motif chemokine receptor 6
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CCR6 mRNA
CTD
PMID:21404309
NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
G
Ccr7
C-C motif chemokine receptor 7
increases expression multiple interactions decreases expression
EXP ISO
Dinitrochlorobenzene results in increased expression of CCR7 mRNA Dinitrochlorobenzene results in increased expression of CCR7 mRNA; Dinitrochlorobenzene results in increased expression of CCR7 protein TNF protein affects the reaction [Dinitrochlorobenzene results in increased expression of CCR7 mRNA] Dinitrochlorobenzene results in decreased expression of CCR7 mRNA
CTD
PMID:15304089 PMID:15737199 PMID:17374397 PMID:19159591 PMID:19371601 PMID:20713136 PMID:28219650 More...
NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
G
Cct3
chaperonin containing TCP1 subunit 3
affects binding
ISO
Dinitrochlorobenzene binds to CCT3 protein
CTD
PMID:32991956
NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757
G
Cct4
chaperonin containing TCP1 subunit 4
affects binding
ISO
Dinitrochlorobenzene binds to CCT4 protein
CTD
PMID:32991956
NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
G
Cct5
chaperonin containing TCP1 subunit 5
affects binding
ISO
Dinitrochlorobenzene binds to CCT5 protein
CTD
PMID:32991956
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
G
Cd109
CD109 molecule
affects binding increases expression
ISO
Dinitrochlorobenzene binds to CD109 protein Dinitrochlorobenzene results in increased expression of CD109 protein
CTD
PMID:32991956 PMID:33774146
NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
G
Cd160
CD160 molecule
affects expression
ISO
Dinitrochlorobenzene affects the expression of CD160 mRNA
CTD
PMID:22302311
NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834
G
Cd207
CD207 molecule
affects expression
ISO
Dinitrochlorobenzene affects the expression of CD207 mRNA
CTD
PMID:22302311
NCBI chr 4:116,155,229...116,161,587
Ensembl chr 4:116,155,212...116,161,518
G
Cd274
CD274 molecule
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CD274 mRNA; Dinitrochlorobenzene results in increased expression of CD274 protein
CTD
PMID:20488241 PMID:28941582
NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
G
Cd36
CD36 molecule
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CD36 mRNA
CTD
PMID:17374397 PMID:21404309
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Cd40
CD40 molecule
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CD40 protein
CTD
PMID:17636246 PMID:21742781
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
G
Cd5l
Cd5 molecule-like
affects expression
ISO
Dinitrochlorobenzene affects the expression of CD5L mRNA
CTD
PMID:22302311
NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753
G
Cd80
Cd80 molecule
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CD80 mRNA
CTD
PMID:28219650
NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
G
Cd83
CD83 molecule
affects expression increases expression decreases expression
ISO
Dinitrochlorobenzene affects the expression of CD83 mRNA Dinitrochlorobenzene results in increased expression of CD83 mRNA; Dinitrochlorobenzene results in increased expression of CD83 protein Dinitrochlorobenzene results in decreased expression of CD83 mRNA
CTD
PMID:17636246 PMID:22302311 PMID:28219650 PMID:28941582
NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
G
Cd86
CD86 molecule
increases expression multiple interactions affects expression
ISO
Dinitrochlorobenzene results in increased expression of CD86 mRNA; Dinitrochlorobenzene results in increased expression of CD86 protein Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of CD86 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; bisindolylmaleimide I inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; cariporide inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Citric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Cysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Glutathione inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Hydrochloric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Lactic Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Vitamin E inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein] Dinitrochlorobenzene affects the expression of CD86 mRNA
CTD
PMID:12423654 PMID:15737199 PMID:17374397 PMID:17636246 PMID:19033392 PMID:19665512 PMID:20417223 PMID:20457211 PMID:20488241 PMID:21742781 PMID:24136171 PMID:28219650 PMID:28389280 PMID:29743441 PMID:30842373 PMID:33774146 More...
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
G
Cdc20
cell division cycle 20
affects expression increases expression
ISO
Dinitrochlorobenzene affects the expression of CDC20 mRNA Dinitrochlorobenzene results in increased expression of CDC20 mRNA
CTD
PMID:21404309 PMID:22302311
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
G
Cdc25c
cell division cycle 25C
affects expression increases expression
ISO
Dinitrochlorobenzene affects the expression of CDC25C mRNA Dinitrochlorobenzene results in increased expression of CDC25C mRNA
CTD
PMID:21404309 PMID:22302311
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
G
Cdc45
cell division cycle 45
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CDC45 mRNA
CTD
PMID:21404309
NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
G
Cdc5l
cell division cycle 5-like
affects binding
ISO
Dinitrochlorobenzene binds to CDC5L protein
CTD
PMID:32991956
NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450
G
Cdc6
cell division cycle 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CDC6 mRNA
CTD
PMID:21404309
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
G
Cdca2
cell division cycle associated 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CDCA2 mRNA
CTD
PMID:18242016
NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
G
Cdh8
cadherin 8
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CDH8 mRNA
CTD
PMID:17374397
NCBI chr19:5,494,038...5,901,810
Ensembl chr19:5,494,174...5,895,669
G
Cdk1
cyclin-dependent kinase 1
affects expression increases expression
ISO
Dinitrochlorobenzene affects the expression of CDK1 mRNA Dinitrochlorobenzene results in increased expression of CDK1 mRNA
CTD
PMID:21404309 PMID:22302311
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
G
Cdk12
cyclin-dependent kinase 12
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CDK12 mRNA
CTD
PMID:25236440
NCBI chr10:83,201,177...83,256,906
Ensembl chr10:83,201,211...83,280,888 Ensembl chr10:83,201,211...83,280,888
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CDKN1A mRNA
CTD
PMID:16314067 PMID:21404309
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
G
Cdkn1c
cyclin-dependent kinase inhibitor 1C
increases expression decreases expression
ISO
Dinitrochlorobenzene results in increased expression of CDKN1C mRNA Dinitrochlorobenzene results in decreased expression of CDKN1C mRNA
CTD
PMID:20146380 PMID:21404309
NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
G
Cebpz
CCAAT/enhancer binding protein zeta
affects binding
ISO
Dinitrochlorobenzene binds to CEBPZ protein
CTD
PMID:32991956
NCBI chr 6:16,119,871...16,137,600
Ensembl chr 6:16,119,872...16,137,600
G
Celf1
CUGBP, Elav-like family member 1
affects binding
ISO
Dinitrochlorobenzene binds to CELF1 protein
CTD
PMID:32991956
NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426
G
Cerkl
ceramide kinase-like
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CERKL mRNA
CTD
PMID:17374397
NCBI chr 3:64,238,714...64,344,695
Ensembl chr 3:64,237,522...64,340,675
G
Ces1d
carboxylesterase 1D
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CES1 mRNA
CTD
PMID:19524605
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
G
Cfap91
cilia and flagella associated protein 91
affects binding
ISO
Dinitrochlorobenzene binds to MAATS1 protein
CTD
PMID:32991956
NCBI chr11:62,413,613...62,457,281
Ensembl chr11:62,413,602...62,457,293
G
Chd3
chromodomain helicase DNA binding protein 3
affects binding
ISO
Dinitrochlorobenzene binds to CHD3 protein
CTD
PMID:32991956
NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047
G
Chd4
chromodomain helicase DNA binding protein 4
affects binding
ISO
Dinitrochlorobenzene binds to CHD4 protein
CTD
PMID:32991956
NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
G
Chd5
chromodomain helicase DNA binding protein 5
affects binding
ISO
Dinitrochlorobenzene binds to CHD5 protein
CTD
PMID:32991956
NCBI chr 5:162,848,273...162,898,997
Ensembl chr 5:162,848,394...162,896,291
G
Chid1
chitinase domain containing 1
affects binding
ISO
Dinitrochlorobenzene binds to CHID1 protein
CTD
PMID:32991956
NCBI chr 1:196,594,357...196,629,700
Ensembl chr 1:196,587,509...196,629,606
G
Cidec
cell death-inducing DFFA-like effector c
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CIDEC mRNA
CTD
PMID:17374397
NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
G
Cisd1
CDGSH iron sulfur domain 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CISD1 mRNA
CTD
PMID:17374397
NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
G
Clasp1
cytoplasmic linker associated protein 1
affects binding
ISO
Dinitrochlorobenzene binds to CLASP1 protein
CTD
PMID:32991956
NCBI chr13:29,493,554...29,715,151
Ensembl chr13:29,493,596...29,715,146
G
Clec5a
C-type lectin domain containing 5A
increases expression affects expression
ISO
Dinitrochlorobenzene results in increased expression of CLEC5A protein Dinitrochlorobenzene affects the expression of CLEC5A mRNA
CTD
PMID:33774146
NCBI chr 4:69,407,125...69,416,872
Ensembl chr 4:69,407,835...69,416,859
G
Clic1
chloride intracellular channel 1
affects binding
ISO
Dinitrochlorobenzene binds to CLIC1 protein
CTD
PMID:32991956
NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
G
Clic4
chloride intracellular channel 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CLIC4 mRNA
CTD
PMID:16314067
NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
G
Cln8
CLN8, transmembrane ER and ERGIC protein
affects binding
ISO
Dinitrochlorobenzene binds to CLN8 protein
CTD
PMID:32991956
NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
G
Cmpk2
cytidine/uridine monophosphate kinase 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CMPK2 mRNA
CTD
PMID:17374397
NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
G
Cnn3
calponin 3
affects binding
ISO
Dinitrochlorobenzene binds to CNN3 protein
CTD
PMID:32991956
NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104
G
Cnot1
CCR4-NOT transcription complex, subunit 1
affects binding
ISO
Dinitrochlorobenzene binds to CNOT1 protein
CTD
PMID:32991956
NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
G
Cnot9
CCR4-NOT transcription complex subunit 9
affects binding
ISO
Dinitrochlorobenzene binds to CNOT9 protein
CTD
PMID:32991956
NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100
G
Cog4
component of oligomeric golgi complex 4
affects binding
ISO
Dinitrochlorobenzene binds to COG4 protein
CTD
PMID:32991956
NCBI chr19:38,820,478...38,854,803
Ensembl chr19:38,820,501...38,854,796
G
Commd3
COMM domain containing 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of COMMD3 mRNA
CTD
PMID:21404309
NCBI chr17:81,327,444...81,331,191
Ensembl chr17:81,327,405...81,331,177
G
Cope
COPI coat complex subunit epsilon
affects binding
ISO
Dinitrochlorobenzene binds to COPE protein
CTD
PMID:32991956
NCBI chr16:19,114,871...19,125,076
Ensembl chr16:19,114,871...19,128,907
G
Cox4i1
cytochrome c oxidase subunit 4i1
affects binding
ISO
Dinitrochlorobenzene binds to COX4I1 protein
CTD
PMID:32991956
NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
G
Cphx1
cytoplasmic polyadenylated homeobox 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of CPHX1 mRNA
CTD
PMID:22302311
NCBI chr16:1,533,883...1,537,248
Ensembl chr16:1,528,440...1,537,082
G
Cpne3
copine 3
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CPNE3 mRNA
CTD
PMID:17374397
NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934
G
Creb1
cAMP responsive element binding protein 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of CREB1 mRNA
CTD
PMID:20385217
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
G
Crem
cAMP responsive element modulator
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CREM mRNA
CTD
PMID:17374397 PMID:19371601
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
G
Crkl
CRK like proto-oncogene, adaptor protein
affects binding
ISO
Dinitrochlorobenzene binds to CRKL protein
CTD
PMID:32991956
NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
G
Crocc
ciliary rootlet coiled-coil, rootletin
affects binding
ISO
Dinitrochlorobenzene binds to CROCC protein
CTD
PMID:32991956
NCBI chr 5:153,320,962...153,363,734
Ensembl chr 5:153,320,962...153,363,578
G
Csf2
colony stimulating factor 2
increases expression increases secretion
ISO
Dinitrochlorobenzene results in increased expression of CSF2 mRNA Dinitrochlorobenzene results in increased secretion of CSF2 protein
CTD
PMID:18652873 PMID:22245253
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
G
Csf2ra
colony stimulating factor 2 receptor subunit alpha
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CSF2RA mRNA
CTD
PMID:19647056
NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128
G
Csf2rb
colony stimulating factor 2 receptor subunit beta
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CSF2RB mRNA; Dinitrochlorobenzene results in increased expression of CSF2RB2 mRNA
CTD
PMID:19647056
NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157
G
Csf3
colony stimulating factor 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CSF3 mRNA
CTD
PMID:18652873
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
G
Csf3r
colony stimulating factor 3 receptor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CSF3R mRNA
CTD
PMID:19647056
NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881
G
Ctla4
cytotoxic T-lymphocyte-associated protein 4
affects expression
ISO
Dinitrochlorobenzene affects the expression of CTLA4 mRNA
CTD
PMID:22302311
NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
G
Ctnna1
catenin alpha 1
affects binding
ISO
Dinitrochlorobenzene binds to CTNNA1 protein
CTD
PMID:32991956
NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
G
Ctnna2
catenin alpha 2
affects binding
ISO
Dinitrochlorobenzene binds to CTNNA2 protein
CTD
PMID:32991956
NCBI chr 4:109,294,249...110,443,409
Ensembl chr 4:109,293,978...110,443,522
G
Ctnnbl1
catenin, beta like 1
affects binding
ISO
Dinitrochlorobenzene binds to CTNNBL1 protein
CTD
PMID:32991956
NCBI chr 3:146,387,940...146,548,987
Ensembl chr 3:146,387,889...146,548,987
G
Ctps2
CTP synthase 2
affects binding
ISO
Dinitrochlorobenzene binds to CTPS2 protein
CTD
PMID:32991956
NCBI chr X:31,645,873...31,786,733
Ensembl chr X:31,645,873...31,786,733
G
Ctsb
cathepsin B
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of CTSB mRNA Dinitrochlorobenzene binds to CTSB protein
CTD
PMID:16314067 PMID:32991956
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
G
Ctsc
cathepsin C
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CTSC mRNA
CTD
PMID:17374397
NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
G
Ctsl
cathepsin L
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CTSL mRNA
CTD
PMID:17374397
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
G
Cul1
cullin 1
affects binding
ISO
Dinitrochlorobenzene binds to CUL1 protein
CTD
PMID:32991956
NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
G
Cul4a
cullin 4A
affects binding
ISO
Dinitrochlorobenzene binds to CUL4A protein
CTD
PMID:32991956
NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
G
Cxcl1
C-X-C motif chemokine ligand 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CXCL1 mRNA
CTD
PMID:20146380 PMID:20713136
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
G
Cxcl10
C-X-C motif chemokine ligand 10
increases expression affects expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of CXCL10 mRNA Dinitrochlorobenzene affects the expression of CXCL10 mRNA NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL10 mRNA]
CTD
PMID:19647056 PMID:20146380 PMID:21404309 PMID:28219650
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cxcl14
C-X-C motif chemokine ligand 14
increases expression decreases expression
ISO
Dinitrochlorobenzene results in increased expression of CXCL14 mRNA Dinitrochlorobenzene results in decreased expression of CXCL14 protein
CTD
PMID:19647056 PMID:31734321
NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
G
Cxcl16
C-X-C motif chemokine ligand 16
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CXCL16 mRNA
CTD
PMID:21404309
NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592
G
Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CXCL2 mRNA Dinitrochlorobenzene results in increased expression of CXCL2 mRNA; Dinitrochlorobenzene results in increased expression of CXCL2 protein
CTD
PMID:16675337 PMID:19647056 PMID:20146380 PMID:23178550 PMID:28826779
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
G
Cxcl3
C-X-C motif chemokine ligand 3
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of CXCL1 mRNA NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL1 mRNA]
CTD
PMID:19647056 PMID:20146380 PMID:20713136 PMID:21404309 PMID:28219650 PMID:28826779 More...
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
G
Cxcl9
C-X-C motif chemokine ligand 9
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CXCL9 mRNA
CTD
PMID:21404309
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
G
Cxcr1
C-X-C motif chemokine receptor 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CXCR1 protein
CTD
PMID:33774146
NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084
G
Cxcr2
C-X-C motif chemokine receptor 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CXCR2 mRNA
CTD
PMID:19647056
NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
G
Cxcr3
C-X-C motif chemokine receptor 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CXCR3 protein
CTD
PMID:33774146
NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969
G
Cxcr4
C-X-C motif chemokine receptor 4
decreases expression increases expression
ISO
Dinitrochlorobenzene results in decreased expression of CXCR4 mRNA Dinitrochlorobenzene results in increased expression of CXCR4 mRNA
CTD
PMID:17374397 PMID:19371601 PMID:19647056 PMID:20146380 PMID:28219650
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
G
Cxcr6
C-X-C motif chemokine receptor 6
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of CXCR6 mRNA
CTD
PMID:21404309
NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CYP1A1 mRNA
CTD
PMID:20491607
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cytip
cytohesin 1 interacting protein
increases expression
ISO
Dinitrochlorobenzene results in increased expression of CYTIP mRNA
CTD
PMID:17374397 PMID:19371601
NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993
G
Dact1
dishevelled-binding antagonist of beta-catenin 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DACT1 mRNA
CTD
PMID:18242016
NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
G
Dap3
death associated protein 3
affects binding
ISO
Dinitrochlorobenzene binds to DAP3 protein
CTD
PMID:32991956
NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461
G
Dcps
decapping enzyme, scavenger
affects binding
ISO
Dinitrochlorobenzene binds to DCPS protein
CTD
PMID:32991956
NCBI chr 8:33,468,669...33,524,407
Ensembl chr 8:33,415,671...33,524,389
G
Dctpp1
dCTP pyrophosphatase 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DCTPP1 mRNA
CTD
PMID:17374397
NCBI chr 1:181,877,440...181,880,833
Ensembl chr 1:181,877,437...181,880,839
G
Ddit3
DNA-damage inducible transcript 3
multiple interactions increases expression
ISO
Glutathione inhibits the reaction [Dinitrochlorobenzene results in increased expression of DDIT3 mRNA]
CTD
PMID:17171638
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
G
Ddx1
DEAD-box helicase 1
affects binding
ISO
Dinitrochlorobenzene binds to DDX1 protein
CTD
PMID:32991956
NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
G
Ddx18
DEAD-box helicase 18
affects binding
ISO
Dinitrochlorobenzene binds to DDX18 protein
CTD
PMID:32991956
NCBI chr13:32,729,697...32,743,161
Ensembl chr13:32,729,700...32,743,161
G
Ddx52
DExD-box helicase 52
affects binding
ISO
Dinitrochlorobenzene binds to DDX52 protein
CTD
PMID:32991956
NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266
G
Ddx56
DEAD-box helicase 56
affects binding
ISO
Dinitrochlorobenzene binds to DDX56 protein
CTD
PMID:32991956
NCBI chr14:81,112,008...81,122,331
Ensembl chr14:81,112,012...81,122,333
G
Dhps
deoxyhypusine synthase
affects binding
ISO
Dinitrochlorobenzene binds to DHPS protein
CTD
PMID:32991956
NCBI chr19:23,082,454...23,086,544
Ensembl chr19:23,082,448...23,086,881
G
Dhx36
DEAH-box helicase 36
affects binding
ISO
Dinitrochlorobenzene binds to DHX36 protein
CTD
PMID:32991956
NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
G
Dhx9
DExH-box helicase 9
increases metabolic processing affects binding
ISO
Dinitrochlorobenzene results in increased metabolism of DHX9 protein Dinitrochlorobenzene binds to DHX9 protein
CTD
PMID:29267982 PMID:32991956
NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
G
Diaph1
diaphanous-related formin 1
affects binding
ISO
Dinitrochlorobenzene binds to DIAPH1 protein
CTD
PMID:32991956
NCBI chr18:29,669,659...29,769,070
Ensembl chr18:29,669,659...29,769,172
G
Dkc1
dyskerin pseudouridine synthase 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DKC1 mRNA
CTD
PMID:17374397
G
Dld
dihydrolipoamide dehydrogenase
affects binding
ISO
Dinitrochlorobenzene binds to DLD protein
CTD
PMID:32991956
NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
G
Dlgap5
DLG associated protein 5
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DLGAP5 mRNA
CTD
PMID:17374397
NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
G
Dnajb4
DnaJ heat shock protein family (Hsp40) member B4
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of DNAJB4 mRNA NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of DNAJB4 mRNA]
CTD
PMID:23999411 PMID:27965148
NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
G
Dnajb6
DnaJ heat shock protein family (Hsp40) member B6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of DNAJB6 mRNA
CTD
PMID:17374397
NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
G
Dnmt1
DNA methyltransferase 1
affects binding
ISO
Dinitrochlorobenzene binds to DNMT1 protein
CTD
PMID:32991956
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
G
Dnmt3b
DNA methyltransferase 3 beta
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DNMT3B mRNA
CTD
PMID:25236440
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
G
Dock5
dedicator of cytokinesis 5
affects binding
ISO
Dinitrochlorobenzene binds to DOCK5 protein
CTD
PMID:32991956
NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649
G
Dpyd
dihydropyrimidine dehydrogenase
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DPYD mRNA
CTD
PMID:17374397
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
G
Dpysl2
dihydropyrimidinase-like 2
affects binding
ISO
Dinitrochlorobenzene binds to DPYSL2 protein
CTD
PMID:32991956
NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
G
Dse
dermatan sulfate epimerase
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of DSE mRNA
CTD
PMID:17374397
NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
G
Dtymk
deoxythymidylate kinase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of DTYMK mRNA
CTD
PMID:21404309
NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
G
Dusp1
dual specificity phosphatase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of DUSP1 mRNA
CTD
PMID:16314067
NCBI chr10:16,680,478...16,683,275
G
Dusp3
dual specificity phosphatase 3
affects binding
ISO
Dinitrochlorobenzene binds to DUSP3 protein
CTD
PMID:32991956
NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
G
Dusp4
dual specificity phosphatase 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of DUSP4 mRNA
CTD
PMID:18242016
NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
G
Dut
deoxyuridine triphosphatase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of DUT mRNA
CTD
PMID:18242016 PMID:21404309
NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
G
E2f1
E2F transcription factor 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of E2F1 mRNA
CTD
PMID:22302311
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
G
Ecd
ecdysoneless cell cycle regulator
affects binding
ISO
Dinitrochlorobenzene binds to ECD protein
CTD
PMID:32991956
NCBI chr15:3,967,209...3,998,713
Ensembl chr15:3,967,382...3,998,706
G
Ecpas
Ecm29 proteasome adaptor and scaffold
affects binding
ISO
Dinitrochlorobenzene binds to ECPAS protein
CTD
PMID:32991956
NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860
G
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
affects binding
ISO
Dinitrochlorobenzene binds to EEF1A2 protein
CTD
PMID:32991956
NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071
G
Egf
epidermal growth factor
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of EGF mRNA
CTD
PMID:20146380
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
G
Egfr
epidermal growth factor receptor
affects binding
ISO
Dinitrochlorobenzene binds to EGFR protein
CTD
PMID:32991956
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Egr2
early growth response 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of EGR2 mRNA
CTD
PMID:17374397
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
G
Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of EHHADH mRNA
CTD
PMID:17374397
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
G
Eif3a
eukaryotic translation initiation factor 3, subunit A
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of EIF3A protein
CTD
PMID:29267982
NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
G
Eif3g
eukaryotic translation initiation factor 3, subunit G
affects binding
ISO
Dinitrochlorobenzene binds to EIF3G protein
CTD
PMID:32991956
NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808
G
Eif4b
eukaryotic translation initiation factor 4B
affects binding
ISO
Dinitrochlorobenzene binds to EIF4B protein
CTD
PMID:32991956
NCBI chr 7:133,206,637...133,228,436
G
Eif4g3
eukaryotic translation initiation factor 4 gamma, 3
affects binding
ISO
Dinitrochlorobenzene binds to EIF4G3 protein
CTD
PMID:32991956
NCBI chr 5:150,197,410...150,418,862
Ensembl chr 5:150,195,226...150,418,363
G
Elac2
elaC ribonuclease Z 2
affects binding
ISO
Dinitrochlorobenzene binds to ELAC2 protein
CTD
PMID:32991956
NCBI chr10:49,632,308...49,655,614
Ensembl chr10:49,632,378...49,655,614
G
Elavl1
ELAV like RNA binding protein 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ELAVL1 protein
CTD
PMID:21969073
NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784
G
Elmod2
ELMO domain containing 2
affects binding
ISO
Dinitrochlorobenzene binds to ELMOD2 protein
CTD
PMID:32991956
NCBI chr19:24,786,166...24,805,626
Ensembl chr19:24,786,241...24,805,130
G
Emb
embigin
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of EMB mRNA
CTD
PMID:17374397
NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050
G
Emd
emerin
affects expression
ISO
Dinitrochlorobenzene affects the expression of EMD mRNA
CTD
PMID:19527780
NCBI chr X:152,038,990...152,042,190
Ensembl chr X:152,038,998...152,045,807
G
Epor
erythropoietin receptor
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of EPOR mRNA
CTD
PMID:21404309
NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
G
Eprs1
glutamyl-prolyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to EPRS1 protein
CTD
PMID:32991956
NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
G
Ercc6
ERCC excision repair 6, chromatin remodeling factor
affects binding
ISO
Dinitrochlorobenzene binds to ERCC6 protein
CTD
PMID:32991956
NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
G
Ercc6l
ERCC excision repair 6 like, spindle assembly checkpoint helicase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ERCC6L mRNA
CTD
PMID:18242016
NCBI chr X:67,245,414...67,261,222
Ensembl chr X:67,245,414...67,280,756
G
Esd
esterase D
affects binding
ISO
Dinitrochlorobenzene binds to ESD protein
CTD
PMID:32991956
NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
G
Esr1
estrogen receptor 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of ESR1 mRNA
CTD
PMID:19527780
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Esyt2
extended synaptotagmin 2
affects binding
ISO
Dinitrochlorobenzene binds to ESYT2 protein
CTD
PMID:32991956
NCBI chr 6:137,219,653...137,312,590
Ensembl chr 6:137,219,707...137,312,590
G
Evpl
envoplakin
affects binding
ISO
Dinitrochlorobenzene binds to EVPL protein
CTD
PMID:32991956
NCBI chr10:101,458,227...101,474,778
Ensembl chr10:101,458,216...101,474,763
G
Exoc1
exocyst complex component 1
affects binding
ISO
Dinitrochlorobenzene binds to EXOC1 protein
CTD
PMID:32991956
NCBI chr14:31,611,536...31,659,920
Ensembl chr14:31,611,547...31,659,914
G
Exoc6b
exocyst complex component 6B
affects binding
ISO
Dinitrochlorobenzene binds to EXOC6B protein
CTD
PMID:32991956
NCBI chr 4:117,094,741...117,550,221
Ensembl chr 4:117,094,741...117,550,180
G
Ezr
ezrin
affects binding
ISO
Dinitrochlorobenzene binds to EZR protein
CTD
PMID:32991956
NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
G
F13a1
coagulation factor XIII A1 chain
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of F13A1 mRNA
CTD
PMID:17374397
NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
G
Fabp1
fatty acid binding protein 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of FABP1 mRNA
CTD
PMID:18242016
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
G
Fabp7
fatty acid binding protein 7
affects expression
ISO
Dinitrochlorobenzene affects the expression of FABP7 mRNA
CTD
PMID:22302311
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
G
Fam3c
FAM3 metabolism regulating signaling molecule C
affects binding
ISO
Dinitrochlorobenzene binds to FAM3C protein
CTD
PMID:32991956
NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078
G
Fam76b
family with sequence similarity 76, member B
affects binding
ISO
Dinitrochlorobenzene binds to FAM76B protein
CTD
PMID:32991956
NCBI chr 8:10,689,396...10,711,847
Ensembl chr 8:10,688,963...10,711,861
G
Farsa
phenylalanyl-tRNA synthetase subunit alpha
affects binding
ISO
Dinitrochlorobenzene binds to FARSA protein
CTD
PMID:32991956
NCBI chr19:23,291,409...23,300,985
Ensembl chr19:23,268,869...23,300,980
G
Fasn
fatty acid synthase
affects binding
ISO
Dinitrochlorobenzene binds to FASN protein
CTD
PMID:32991956
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fbxo9
f-box protein 9
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of FBXO9 mRNA
CTD
PMID:17374397
NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949
G
Fech
ferrochelatase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FECH mRNA
CTD
PMID:20566472
NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
G
Ferry3
FERRY endosomal RAB5 effector complex subunit 3
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of FERRY3 mRNA
CTD
PMID:17374397
NCBI chr 4:159,772,693...159,809,322
Ensembl chr 4:159,772,786...159,806,382
G
Ffar2
free fatty acid receptor 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FFAR2 mRNA
CTD
PMID:18242016
NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033
G
Fgf9
fibroblast growth factor 9
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FGF9 mRNA
CTD
PMID:20146380
NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
G
Fgfr3
fibroblast growth factor receptor 3
affects binding
ISO
Dinitrochlorobenzene binds to FGFR3 protein
CTD
PMID:32991956
NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
G
Fgl2
fibrinogen-like 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of FGL2 mRNA
CTD
PMID:17374397
NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
G
Fkbp8
FKBP prolyl isomerase 8
affects binding
ISO
Dinitrochlorobenzene binds to FKBP8 protein
CTD
PMID:32991956
NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612
G
Flna
filamin A
affects binding
ISO
Dinitrochlorobenzene binds to FLNA protein
CTD
PMID:32991956
NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
G
Flnb
filamin B
affects binding
ISO
Dinitrochlorobenzene binds to FLNB protein
CTD
PMID:32991956
NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FOS mRNA
CTD
PMID:20146380 PMID:25236440
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Fosl1
FOS like 1, AP-1 transcription factor subunit
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FOSL1 mRNA
CTD
PMID:25236440
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
G
Fosl2
FOS like 2, AP-1 transcription factor subunit
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FOSL2 mRNA
CTD
PMID:17374397
NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
G
Frmd7
FERM domain containing 7
affects binding
ISO
Dinitrochlorobenzene binds to FRMD7 protein
CTD
PMID:32991956
NCBI chr X:130,375,925...130,423,836
Ensembl chr X:130,377,227...130,423,771
G
Fscn1
fascin actin-bundling protein 1
affects binding
ISO
Dinitrochlorobenzene binds to FSCN1 protein
CTD
PMID:32991956
NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
G
Fth1
ferritin heavy chain 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FTH1 mRNA
CTD
PMID:16314067
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
G
Ftl1
ferritin light chain 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of FTL mRNA
CTD
PMID:20566472
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
G
Fxyd4
FXYD domain-containing ion transport regulator 4
affects expression
ISO
Dinitrochlorobenzene affects the expression of FXYD4 mRNA
CTD
PMID:22302311
NCBI chr 4:151,109,779...151,113,659
Ensembl chr 4:151,109,779...151,113,637
G
G6pd
glucose-6-phosphate dehydrogenase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of G6PD mRNA
CTD
PMID:20566472
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gal3st1
galactose-3-O-sulfotransferase 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of GAL3ST1 mRNA
CTD
PMID:19527780
NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388
G
Gars1
glycyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to GARS1 protein
CTD
PMID:32991956
NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609
G
Gart
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
affects binding
ISO
Dinitrochlorobenzene binds to GART protein
CTD
PMID:32991956
NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GCLC mRNA
CTD
PMID:20146380 PMID:20566472
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of GCLM mRNA NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of GCLM mRNA]
CTD
PMID:20146380 PMID:20566472 PMID:23999411 PMID:27965148
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gdi2
GDP dissociation inhibitor 2
affects binding
ISO
Dinitrochlorobenzene binds to GDI2 protein
CTD
PMID:32991956
NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366
G
Glyr1
glyoxylate reductase 1 homolog
affects binding
ISO
Dinitrochlorobenzene binds to GLYR1 protein
CTD
PMID:32991956
NCBI chr10:10,532,036...10,567,639
Ensembl chr10:10,532,154...10,567,637
G
Gmpr
guanosine monophosphate reductase
increases methylation
ISO
Dinitrochlorobenzene results in increased methylation of GMPR gene
CTD
PMID:26732893
NCBI chr17:19,151,820...19,189,626
Ensembl chr17:19,151,815...19,189,621
G
Gmps
guanine monophosphate synthase
affects binding
ISO
Dinitrochlorobenzene binds to GMPS protein
CTD
PMID:32991956
NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875
G
Golga2
golgin A2
affects binding
ISO
Dinitrochlorobenzene binds to GOLGA2 protein
CTD
PMID:32991956
NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279
G
Golgb1
golgin B1
affects binding
ISO
Dinitrochlorobenzene binds to GOLGB1 protein
CTD
PMID:32991956
NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770
G
Gon4l
gon-4 like
affects binding
ISO
Dinitrochlorobenzene binds to GON4L protein
CTD
PMID:32991956
NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634
G
Gpat3
glycerol-3-phosphate acyltransferase 3
affects expression
ISO
Dinitrochlorobenzene affects the expression of GPAT3 mRNA
CTD
PMID:33774146
NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
G
Gpd2
glycerol-3-phosphate dehydrogenase 2
affects binding
ISO
Dinitrochlorobenzene binds to GPD2 protein
CTD
PMID:32991956
NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
G
Gpi
glucose-6-phosphate isomerase
affects binding
ISO
Dinitrochlorobenzene binds to GPI protein
CTD
PMID:32991956
NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
G
Gpnmb
glycoprotein nmb
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GPNMB mRNA
CTD
PMID:16314067
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
G
Gpx1
glutathione peroxidase 1
affects expression multiple interactions
ISO
Dinitrochlorobenzene affects the expression of GPX1 mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX1 mRNA]
CTD
PMID:28219650
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gpx2
glutathione peroxidase 2
affects expression multiple interactions
ISO
Dinitrochlorobenzene affects the expression of GPX2 mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX2 mRNA]
CTD
PMID:28219650
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Gpx3
glutathione peroxidase 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GPX3 mRNA
CTD
PMID:20566472
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
G
Gpx5
glutathione peroxidase 5
multiple interactions affects expression
ISO
NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX5 mRNA] Dinitrochlorobenzene affects the expression of GPX5 mRNA
CTD
PMID:28219650
NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074
G
Gpx6
glutathione peroxidase 6
multiple interactions affects expression
ISO
NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX6 mRNA] Dinitrochlorobenzene affects the expression of GPX6 mRNA
CTD
PMID:28219650
NCBI chr17:43,408,472...43,416,091
Ensembl chr17:43,408,472...43,416,091
G
Gpx7
glutathione peroxidase 7
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of GPX7 mRNA
CTD
PMID:28219650
NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004
G
Grap2
GRB2-related adaptor protein 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GRAP2 mRNA
CTD
PMID:21404309
NCBI chr 7:112,117,142...112,190,880
Ensembl chr 7:112,117,142...112,190,877
G
Grem1
gremlin 1, DAN family BMP antagonist
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GREM1 mRNA
CTD
PMID:20146380
NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
G
Grsf1
G-rich RNA sequence binding factor 1
affects binding
ISO
Dinitrochlorobenzene binds to GRSF1 protein
CTD
PMID:32991956
NCBI chr14:19,412,944...19,429,364
Ensembl chr14:19,412,156...19,429,362
G
Gsk3b
glycogen synthase kinase 3 beta
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GSK3B mRNA
CTD
PMID:17374397 PMID:28219650
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Gsr
glutathione-disulfide reductase
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of GSR mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GSR mRNA]
CTD
PMID:20566472 PMID:28219650
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gsta1
glutathione S-transferase alpha 1
multiple interactions increases metabolic processing increases expression
ISO EXP
[GSTA1 protein binds to GSTA1 protein] which affects the metabolism of Dinitrochlorobenzene; [GSTA1 protein binds to GSTA4 protein] which affects the metabolism of Dinitrochlorobenzene; GSTA1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]; GSTA1 protein binds to and affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione] GSTA1 protein results in increased metabolism of Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of GSTA1 protein
CTD
PMID:3138230 PMID:9794801 PMID:11851347 PMID:12147362 PMID:14690442
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
G
Gsta2
glutathione S-transferase alpha 2
increases metabolic processing decreases metabolic processing
ISO
GSTA2 protein results in increased metabolism of Dinitrochlorobenzene GSTA2 protein polymorphism results in decreased metabolism of Dinitrochlorobenzene
CTD
PMID:3138230 PMID:15077012 PMID:15128049
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
G
Gsta3
glutathione S-transferase alpha 3
increases expression
EXP
Dinitrochlorobenzene results in increased expression of GSTA3 protein
CTD
PMID:9794801
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
G
Gsta4
glutathione S-transferase alpha 4
multiple interactions affects metabolic processing affects binding
ISO EXP
[GSTA1 protein binds to GSTA4 protein] which affects the metabolism of Dinitrochlorobenzene; [GSTA4 protein binds to GSTA4 protein] which affects the metabolism of Dinitrochlorobenzene GSTA4 protein affects the metabolism of Dinitrochlorobenzene 1-chloro-2 4-dinitrobenzene binds to Gsta4 protein
CTD RGD
PMID:2619714 PMID:11851347 PMID:11018474
RGD:1641942
NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
G
Gstm1
glutathione S-transferase mu 1
affects metabolic processing affects binding multiple interactions affects expression increases glutathionylation decreases expression
ISO EXP
GSTM1 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene binds to GSTM1 protein GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog] Dinitrochlorobenzene affects the expression of GSTM1 mRNA GSTM1 protein results in increased glutathionylation of Dinitrochlorobenzene Dinitrochlorobenzene results in decreased expression of GSTM1 mRNA
CTD
PMID:2904809 PMID:3570286 PMID:9545290 PMID:12069689 PMID:21404309 PMID:22085405 PMID:28219650 PMID:28762043 More...
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
G
Gstm2
glutathione S-transferase mu 2
affects metabolic processing affects activity multiple interactions increases expression
ISO EXP
GSTM2 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene affects the activity of GSTM2 protein Dinitrochlorobenzene promotes the reaction [GSTM2 protein affects the metabolism of Glutathione] Dinitrochlorobenzene results in increased expression of GSTM2 protein GSTM5 protein affects the metabolism of Dinitrochlorobenzene
CTD
PMID:3570286 PMID:9545290 PMID:9794801
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
G
Gstm4
glutathione S-transferase mu 4
multiple interactions affects metabolic processing
ISO
GSTM4 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione] GSTM4 protein affects the metabolism of Dinitrochlorobenzene
CTD
PMID:8203914 PMID:8349586
NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
G
Gstm5
glutathione S-transferase, mu 5
increases metabolic processing decreases metabolic processing affects metabolic processing increases expression decreases expression
ISO EXP
GSTM3 protein polymorphism results in increased metabolism of Dinitrochlorobenzene GSTM3 protein polymorphism results in decreased metabolism of Dinitrochlorobenzene GSTM3 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of GSTM3 protein Dinitrochlorobenzene results in decreased expression of GSTM3 mRNA
CTD
PMID:3169012 PMID:9545290 PMID:9794801 PMID:15247628 PMID:21404309
NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
G
Gstm5l
glutathione S-transferase, mu 5-like
affects metabolic processing
EXP
GSTM5 protein affects the metabolism of Dinitrochlorobenzene
CTD
PMID:9545290
NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961
G
Gstp1
glutathione S-transferase pi 1
affects metabolic processing increases expression decreases activity multiple interactions affects binding decreases response to substance increases activity
ISO EXP
GSTP1 protein affects the metabolism of Dinitrochlorobenzene; GSTP2 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of GSTP1 protein Dinitrochlorobenzene results in decreased activity of GSTP1 protein GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene; Mercuric Chloride inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene]; methylmercuric chloride inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene]; Sodium Selenite inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene] 1-chloro-2,4-dinitrobenzene binds to Gstp1 protein GSTP1 protein mutant form results in decreased susceptibility to Dinitrochlorobenzene Dinitrochlorobenzene results in increased activity of GSTP1 protein mutant form
CTD RGD
PMID:2619714 PMID:3570286 PMID:9794801 PMID:10870112 PMID:15355982 PMID:22401947 PMID:37031912 PMID:11018474 More...
RGD:1641942
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Gstt1
glutathione S-transferase theta 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of GSTT1 mRNA
CTD
PMID:28219650
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
G
Gstt2
glutathione S-transferase theta 2
increases metabolic processing
EXP
GSTT2 protein results in increased metabolism of Dinitrochlorobenzene
CTD
PMID:12054768
NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
G
Gstz1
glutathione S-transferase zeta 1
affects metabolic processing
ISO
GSTZ1 protein affects the metabolism of Dinitrochlorobenzene
CTD
PMID:1846734
NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
G
Gtf2b
general transcription factor IIB
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GTF2B mRNA
CTD
PMID:17374397
NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
G
Gtf2i
general transcription factor II I
affects binding
ISO
Dinitrochlorobenzene binds to GTF2I protein
CTD
PMID:32991956
NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243
G
Gyg1
glycogenin 1
affects binding
ISO
Dinitrochlorobenzene binds to GYG1 protein
CTD
PMID:32991956
NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797
G
Gzma
granzyme A
increases expression
ISO
Dinitrochlorobenzene results in increased expression of GZMA mRNA
CTD
PMID:18242016
NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493
G
Gzmb
granzyme B
affects expression increases expression
ISO EXP
Dinitrochlorobenzene affects the expression of GZMB mRNA Dinitrochlorobenzene results in increased expression of GZMB mRNA
CTD
PMID:18652873 PMID:21893156 PMID:22302311
NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814
G
Hadha
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
affects binding
ISO
Dinitrochlorobenzene binds to HADHA protein
CTD
PMID:32991956
NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
G
Has1
hyaluronan synthase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HAS1 mRNA; Dinitrochlorobenzene results in increased expression of HAS1 protein
CTD
PMID:31226360
NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397
G
Has2
hyaluronan synthase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HAS2 mRNA; Dinitrochlorobenzene results in increased expression of HAS2 protein
CTD
PMID:31226360
NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
G
Has3
hyaluronan synthase 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HAS3 mRNA; Dinitrochlorobenzene results in increased expression of HAS3 protein
CTD
PMID:31226360
NCBI chr19:34,768,421...34,782,170
Ensembl chr19:34,771,982...34,782,592
G
Hbb
hemoglobin subunit beta
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of HBB protein
CTD
PMID:29267982
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
G
Hdlbp
high density lipoprotein binding protein
affects binding
ISO
Dinitrochlorobenzene binds to HDLBP protein
CTD
PMID:32991956
NCBI chr 9:93,948,099...94,018,040
Ensembl chr 9:93,949,913...94,018,048
G
Heatr1
HEAT repeat containing 1
affects binding
ISO
Dinitrochlorobenzene binds to HEATR1 protein
CTD
PMID:32991956
NCBI chr17:58,053,288...58,093,895
Ensembl chr17:58,051,700...58,093,948
G
Heatr5b
HEAT repeat containing 5B
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of HEATR5B mRNA
CTD
PMID:17374397
NCBI chr 6:16,243,424...16,323,444
Ensembl chr 6:16,243,461...16,323,435
G
Hebp2
heme binding protein 2
affects binding
ISO
Dinitrochlorobenzene binds to HEBP2 protein
CTD
PMID:32991956
NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777
G
Hectd4
HECT domain E3 ubiquitin protein ligase 4
affects binding
ISO
Dinitrochlorobenzene binds to HECTD4 protein
CTD
PMID:32991956
NCBI chr12:35,182,165...35,330,935
Ensembl chr12:35,182,154...35,330,987
G
Hexa
hexosaminidase subunit alpha
affects binding
ISO
Dinitrochlorobenzene binds to HEXA protein
CTD
PMID:32991956
NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
G
Hipk2
homeodomain interacting protein kinase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HIPK2 mRNA
CTD
PMID:16314067
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
G
Hist1h4m
histone cluster 1, H4m
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of H4C1 protein
CTD
PMID:29267982
NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958
G
Hmgb1
high mobility group box 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of HMGB1 mRNA
CTD
PMID:28219650
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
G
Hmox1
heme oxygenase 1
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; BACH1 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]
CTD
PMID:16314067 PMID:19033392 PMID:20146380 PMID:20566472 PMID:20713136 PMID:25236440 PMID:26244607 PMID:28219650 PMID:31967339 More...
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of HNRNPA3 mRNA
CTD
PMID:17374397
NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306
G
Hnrnpc
heterogeneous nuclear ribonucleoprotein C
affects binding
ISO
Dinitrochlorobenzene binds to HNRNPC protein
CTD
PMID:32991956
NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183
G
Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HNRNPLL mRNA
CTD
PMID:21404309
NCBI chr 6:14,969,953...15,000,574
Ensembl chr 6:14,970,057...14,999,745
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
affects binding
ISO
Dinitrochlorobenzene binds to HSD17B4 protein
CTD
PMID:32991956
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of HSPA1A protein
CTD
PMID:29267982
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
G
Hspa2
heat shock protein family A (Hsp70) member 2
affects binding
ISO
Dinitrochlorobenzene binds to HSPA2 protein
CTD
PMID:32991956
NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
G
Hspa6l-ps1
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HSPA6 mRNA
CTD
PMID:16314067 PMID:23999411
NCBI chr13:83,273,176...83,274,317
G
Hspa8
heat shock protein family A (Hsp70) member 8
increases metabolic processing affects binding
ISO
Dinitrochlorobenzene results in increased metabolism of HSPA8 protein Dinitrochlorobenzene binds to HSPA8 protein
CTD
PMID:29267982 PMID:32991956
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
G
Hspb1
heat shock protein family B (small) member 1
affects binding
ISO
Dinitrochlorobenzene binds to HSPB1 protein
CTD
PMID:32991956
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
G
Hspd1
heat shock protein family D (Hsp60) member 1
affects binding
ISO
Dinitrochlorobenzene binds to HSPD1 protein
CTD
PMID:32991956
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
G
Hsph1
heat shock protein family H (Hsp110) member 1
affects binding
ISO
Dinitrochlorobenzene binds to HSPH1 protein
CTD
PMID:32991956
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
G
Hyal1
hyaluronidase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of HYAL1 mRNA
CTD
PMID:31226360
NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
G
Iars1
isoleucyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to IARS1 protein
CTD
PMID:32991956
NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237
G
Icam1
intercellular adhesion molecule 1
increases expression multiple interactions affects expression
ISO
Dinitrochlorobenzene results in increased expression of ICAM1 mRNA; Dinitrochlorobenzene results in increased expression of ICAM1 protein Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein]; cariporide inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Citric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Hydrochloric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Lactic Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Potassium Chloride affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein]
CTD
PMID:15737199 PMID:19427879 PMID:20417223 PMID:21742781 PMID:29743441 PMID:30842373 PMID:33774146 More...
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
G
Id2
inhibitor of DNA binding 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ID2 mRNA
CTD
PMID:20146380
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
G
Ide
insulin degrading enzyme
affects binding
ISO
Dinitrochlorobenzene binds to IDE protein
CTD
PMID:32991956
NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
G
Idi1
isopentenyl-diphosphate delta isomerase 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of IDI1 mRNA
CTD
PMID:17374397
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
G
Ier3
immediate early response 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IER3 mRNA
CTD
PMID:17374397
NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
G
Ifi27
interferon, alpha-inducible protein 27
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IFI27 mRNA
CTD
PMID:18242016
NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
G
Ifi44l
interferon-induced protein 44-like
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IFI44L mRNA
CTD
PMID:18242016
NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
G
Ifit2
interferon-induced protein with tetratricopeptide repeats 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of IFIT2 mRNA
CTD
PMID:17374397
NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
G
Ifng
interferon gamma
multiple interactions increases secretion increases expression decreases expression
ISO EXP
4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG protein]; [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IFNG mRNA; [Dacarbazine co-treated with Dinitrochlorobenzene] results in increased expression of IFNG mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IFNG mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG protein]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG protein] Dinitrochlorobenzene results in increased secretion of IFNG protein Dinitrochlorobenzene results in increased expression of IFNG mRNA; Dinitrochlorobenzene results in increased expression of IFNG protein Dinitrochlorobenzene results in decreased expression of IFNG mRNA
CTD
PMID:10637130 PMID:11708898 PMID:12202904 PMID:12884401 PMID:15588915 PMID:15588918 PMID:18242016 PMID:18652873 PMID:19042193 PMID:19422874 PMID:21404309 PMID:22245253 PMID:23133493 PMID:23200891 PMID:23454147 PMID:23499868 PMID:25449201 PMID:28219650 PMID:29233007 PMID:30017638 More...
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Ifrd1
interferon-related developmental regulator 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IFRD1 mRNA
CTD
PMID:17374397
NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
G
Igbp1
immunoglobulin binding protein 1
affects binding
ISO
Dinitrochlorobenzene binds to IGBP1 protein
CTD
PMID:32991956
NCBI chr X:65,582,832...65,605,078
Ensembl chr X:65,582,821...65,606,049
G
Igfbp6
insulin-like growth factor binding protein 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IGFBP6 mRNA
CTD
PMID:17374397
NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966
G
Il10
interleukin 10
increases expression multiple interactions affects expression decreases expression
ISO
Dinitrochlorobenzene results in increased expression of IL10 protein [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL10 mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL10 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL10 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL10 protein] Dinitrochlorobenzene affects the expression of IL10 mRNA Dinitrochlorobenzene results in decreased expression of IL10 mRNA; Dinitrochlorobenzene results in decreased expression of IL10 protein
CTD
PMID:19422874 PMID:23499868 PMID:28219650 PMID:29233007 PMID:34651546
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il10ra
interleukin 10 receptor subunit alpha
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL10RA mRNA
CTD
PMID:19647056
NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
G
Il11
interleukin 11
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL11 mRNA
CTD
PMID:19647056
NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
G
Il12a
interleukin 12A
increases expression decreases expression
EXP ISO
Dinitrochlorobenzene results in increased expression of IL12A mRNA Dinitrochlorobenzene results in decreased expression of IL12A mRNA
CTD
PMID:25449201 PMID:28219650
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
G
Il12b
interleukin 12B
increases expression increases secretion affects expression decreases methylation increases methylation
ISO EXP
Dinitrochlorobenzene results in increased expression of IL12B mRNA; Dinitrochlorobenzene results in increased expression of IL12B protein Dinitrochlorobenzene results in increased secretion of IL12B protein Dinitrochlorobenzene affects the expression of IL12B mRNA Dinitrochlorobenzene results in decreased methylation of IL12B gene Dinitrochlorobenzene results in increased methylation of IL12B gene
CTD
PMID:10199581 PMID:11708898 PMID:18652873 PMID:22302311 PMID:25449201 PMID:26732893 PMID:28219650 More...
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
G
Il12rb1
interleukin 12 receptor subunit beta 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL12RB1 mRNA
CTD
PMID:18242016 PMID:21404309
NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769
G
Il13
interleukin 13
multiple interactions increases expression
ISO
Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 protein]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 protein] Dinitrochlorobenzene results in increased expression of IL13 mRNA; Dinitrochlorobenzene results in increased expression of IL13 protein
CTD
PMID:23133493 PMID:23200891 PMID:23454147 PMID:29233007
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
G
Il17a
interleukin 17A
multiple interactions increases expression
ISO EXP
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL17A mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL17A mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL17A mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL17A mRNA]
CTD
PMID:23133493 PMID:23499868 PMID:25449201
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
G
Il18
interleukin 18
increases activity increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased activity of IL18 protein Dinitrochlorobenzene results in increased expression of IL18 mRNA Dinitrochlorobenzene results in increased expression of IL18 protein PRDM1 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of IL18 protein]
CTD
PMID:11708898 PMID:15840424 PMID:23063874 PMID:27585668 PMID:28389280
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Il18r1
interleukin 18 receptor 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL18R1 mRNA
CTD
PMID:11708898
NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
G
Il19
interleukin 19
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL19 mRNA
CTD
PMID:19647056
NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
G
Il1a
interleukin 1 alpha
increases activity increases expression multiple interactions affects secretion affects expression
ISO
Dinitrochlorobenzene results in increased activity of IL1A protein Dinitrochlorobenzene results in increased expression of IL1A mRNA; Dinitrochlorobenzene results in increased expression of IL1A protein Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] Dinitrochlorobenzene affects the secretion of IL1A protein Dinitrochlorobenzene affects the expression of IL1A mRNA
CTD
PMID:7476933 PMID:12781210 PMID:15840424 PMID:18652873 PMID:23178550 PMID:28219650 PMID:33715048 More...
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
increases expression multiple interactions increases secretion affects expression
ISO
Dinitrochlorobenzene results in increased expression of IL1B mRNA; Dinitrochlorobenzene results in increased expression of IL1B protein Lipopolysaccharides promotes the reaction [Dinitrochlorobenzene results in increased expression of IL1B mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL1B mRNA] Dinitrochlorobenzene results in increased secretion of IL1B protein Dinitrochlorobenzene affects the expression of IL1B mRNA [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL1B protein
CTD
PMID:11033066 PMID:16314067 PMID:16687389 PMID:18652873 PMID:19647056 PMID:20146380 PMID:21404309 PMID:24964617 PMID:28219650 PMID:28941582 PMID:30842373 PMID:33715048 PMID:33774146 More...
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il1rl1
interleukin 1 receptor-like 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL1RL1 mRNA
CTD
PMID:11708898 PMID:20146380
NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
G
Il2
interleukin 2
increases expression increases secretion
ISO
Dinitrochlorobenzene results in increased expression of IL2 mRNA; Dinitrochlorobenzene results in increased expression of IL2 protein Dinitrochlorobenzene results in increased secretion of IL2 protein
CTD
PMID:15588918 PMID:18652873 PMID:22245253 PMID:22381623
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
G
Il21
interleukin 21
affects expression
ISO
Dinitrochlorobenzene affects the expression of IL21 mRNA
CTD
PMID:22302311
NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
G
Il23a
interleukin 23 subunit alpha
increases expression
EXP
Dinitrochlorobenzene results in increased expression of IL23A mRNA
CTD
PMID:25449201
NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
G
Il24
interleukin 24
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL24 mRNA
CTD
PMID:19647056
NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
G
Il25
interleukin 25
increases methylation
ISO
Dinitrochlorobenzene results in increased methylation of IL25 gene; Dinitrochlorobenzene results in increased methylation of IL25 promoter
CTD
PMID:24675093 PMID:26732893
NCBI chr15:28,408,766...28,412,157
Ensembl chr15:28,408,842...28,411,893
G
Il2ra
interleukin 2 receptor subunit alpha
affects expression increases expression
ISO
Dinitrochlorobenzene affects the expression of IL2RA mRNA Dinitrochlorobenzene results in increased expression of IL2RA mRNA
CTD
PMID:21404309 PMID:22302311
NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
G
Il3
interleukin 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL3 mRNA
CTD
PMID:18652873
NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
G
Il31
interleukin 31
multiple interactions
ISO
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL31 mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL31 mRNA]
CTD
PMID:23499868
NCBI chr12:33,095,108...33,105,026
Ensembl chr12:33,092,097...33,105,037
G
Il4
interleukin 4
affects expression multiple interactions increases expression decreases expression
ISO
Dinitrochlorobenzene affects the expression of IL4 mRNA [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL4 mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL4 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 protein]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 protein]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL4 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL4 protein] Dinitrochlorobenzene results in increased expression of IL4 mRNA; Dinitrochlorobenzene results in increased expression of IL4 protein Dinitrochlorobenzene results in decreased expression of IL4 mRNA; Dinitrochlorobenzene results in decreased expression of IL4 protein
CTD
PMID:15588918 PMID:15664275 PMID:18652873 PMID:19422874 PMID:22302311 PMID:23133493 PMID:23200891 PMID:23454147 PMID:23499868 PMID:28826779 PMID:29233007 PMID:34651546 More...
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il4r
interleukin 4 receptor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL4RA mRNA; Dinitrochlorobenzene results in increased expression of IL4RA protein
CTD
PMID:19647056 PMID:22381623
NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
G
Il5
interleukin 5
multiple interactions increases expression
ISO
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]
CTD
PMID:23133493 PMID:23200891 PMID:23454147 PMID:23499868
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
G
Il6
interleukin 6
multiple interactions increases expression increases secretion
ISO
[Dacarbazine co-treated with Dinitrochlorobenzene] results in increased expression of IL6 mRNA; Lipopolysaccharides promotes the reaction [Dinitrochlorobenzene results in increased expression of IL6 mRNA] Dinitrochlorobenzene results in increased expression of IL6 mRNA; Dinitrochlorobenzene results in increased expression of IL6 protein Dinitrochlorobenzene results in increased secretion of IL6 protein [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL6 protein
CTD
PMID:11378323 PMID:12202904 PMID:16687389 PMID:18652873 PMID:19647056 PMID:22245253 PMID:24964617 PMID:28941582 More...
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Il7
interleukin 7
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of IL7 mRNA
CTD
PMID:18242016 PMID:21404309
NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
G
Il7r
interleukin 7 receptor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IL7R mRNA
CTD
PMID:20713136
NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
G
Ilf3
interleukin enhancer binding factor 3
affects binding
ISO
Dinitrochlorobenzene binds to ILF3 protein
CTD
PMID:32991956
NCBI chr 8:19,922,409...19,960,495
Ensembl chr 8:19,922,460...19,960,350
G
Inhba
inhibin subunit beta A
increases expression
ISO
Dinitrochlorobenzene results in increased expression of INHBA mRNA
CTD
PMID:19647056
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
G
Ipcef1
interaction protein for cytohesin exchange factors 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of IPCEF1 mRNA
CTD
PMID:17374397
NCBI chr 1:43,237,903...43,451,735
Ensembl chr 1:43,269,202...43,427,969
G
Ipo7
importin 7
affects binding
ISO
Dinitrochlorobenzene binds to IPO7 protein
CTD
PMID:32991956
NCBI chr 1:164,062,702...164,102,938
Ensembl chr 1:164,062,702...164,102,938
G
Ipo8
importin 8
affects binding
ISO
Dinitrochlorobenzene binds to IPO8 protein
CTD
PMID:32991956
NCBI chr 4:181,729,216...181,793,672
Ensembl chr 4:181,729,220...181,793,161
G
Ipo9
importin 9
affects binding
ISO
Dinitrochlorobenzene binds to IPO9 protein
CTD
PMID:32991956
NCBI chr13:46,810,460...46,862,694
Ensembl chr13:46,813,171...46,862,673
G
Iqgap1
IQ motif containing GTPase activating protein 1
affects binding
ISO
Dinitrochlorobenzene binds to IQGAP1 protein
CTD
PMID:32991956
NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
G
Iqgap2
IQ motif containing GTPase activating protein 2
affects binding
ISO
Dinitrochlorobenzene binds to IQGAP2 protein
CTD
PMID:32991956
NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279
G
Irf1
interferon regulatory factor 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of IRF1 mRNA
CTD
PMID:20146380
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
G
Itgav
integrin subunit alpha V
affects expression
ISO
Dinitrochlorobenzene affects the expression of ITGAV mRNA
CTD
PMID:22302311
NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
G
Ivl
involucrin
affects binding
ISO
Dinitrochlorobenzene binds to IVL protein
CTD
PMID:32991956
NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Dinitrochlorobenzene results in increased expression of JUN mRNA
CTD
PMID:16314067
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of KCNJ2 mRNA
CTD
PMID:17374397
NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
G
Keap1
Kelch-like ECH-associated protein 1
multiple interactions affects metabolic processing increases expression decreases expression
ISO
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of KEAP1 protein]; Dinitrochlorobenzene promotes the reaction [KEAP1 protein binds to KEAP1 protein]; tetrachlorobenzoquinone promotes the reaction [Dinitrochlorobenzene promotes the reaction [KEAP1 protein binds to KEAP1 protein]] Dinitrochlorobenzene affects the metabolism of KEAP1 protein Dinitrochlorobenzene results in decreased expression of KEAP1 mRNA
CTD
PMID:18785192 PMID:19033392 PMID:25742418 PMID:28219650
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
G
Kif23
kinesin family member 23
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of KIF23 mRNA
CTD
PMID:17374397
NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
G
Kifc1
kinesin family member C1
affects binding
ISO
Dinitrochlorobenzene binds to KIFC1 protein
CTD
PMID:32991956
NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
G
Kitlg
KIT ligand
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of KITL mRNA
CTD
PMID:21404309
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
G
Klf6
KLF transcription factor 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of KLF6 mRNA
CTD
PMID:16314067 PMID:17374397
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
G
Kpna2
karyopherin subunit alpha 2
affects binding
ISO
Dinitrochlorobenzene binds to KPNA2 protein
CTD
PMID:32991956
NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
G
Krr1
KRR1, small subunit processome component homolog
affects binding
ISO
Dinitrochlorobenzene binds to KRR1 protein
CTD
PMID:32991956
NCBI chr 7:47,475,557...47,486,996
Ensembl chr 7:47,475,557...47,486,985
G
Krt14
keratin 14
affects binding
ISO
Dinitrochlorobenzene binds to KRT14 protein
CTD
PMID:32991956
NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799
G
Krt16
keratin 16
affects binding
ISO
Dinitrochlorobenzene binds to KRT16 protein
CTD
PMID:32991956
NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799
G
Krt17
keratin 17
affects binding
ISO
Dinitrochlorobenzene binds to KRT17 protein
CTD
PMID:32991956
NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
G
Krt2
keratin 2
affects binding
ISO
Dinitrochlorobenzene binds to KRT2 protein
CTD
PMID:32991956
NCBI chr 7:132,940,879...132,948,031
Ensembl chr 7:132,940,862...132,947,963
G
Krt4
keratin 4
affects binding
ISO
Dinitrochlorobenzene binds to KRT4 protein
CTD
PMID:32991956
NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019
G
Krt5
keratin 5
affects binding
ISO
Dinitrochlorobenzene binds to KRT5 protein
CTD
PMID:32991956
NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850
G
Krt6c
keratin 6c
affects binding
ISO
Dinitrochlorobenzene binds to KRT6C protein
CTD
PMID:32991956
NCBI chr 7:132,799,608...132,804,045
Ensembl chr 7:132,799,616...132,804,045
G
Krt73
keratin 73
affects binding
ISO
Dinitrochlorobenzene binds to KRT73 protein
CTD
PMID:32991956
NCBI chr 7:132,927,812...132,936,323
Ensembl chr 7:132,928,256...132,936,280
G
Krt75
keratin 75
affects binding
ISO
Dinitrochlorobenzene binds to KRT75 protein
CTD
PMID:32991956
NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345
G
Krt76
keratin 76
affects binding
ISO
Dinitrochlorobenzene binds to KRT76 protein
CTD
PMID:32991956
NCBI chr 7:133,016,990...133,025,475
Ensembl chr 7:133,016,992...133,025,496
G
Krt78
keratin 78
affects binding
ISO
Dinitrochlorobenzene binds to KRT78 protein
CTD
PMID:32991956
NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021
G
Lamp2
lysosomal-associated membrane protein 2
affects binding
ISO
Dinitrochlorobenzene binds to LAMP2 protein
CTD
PMID:32991956
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Lgals7
galectin 7
affects expression
ISO
Dinitrochlorobenzene affects the expression of LGALS7 mRNA
CTD
PMID:22302311
NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015
G
Lig1
DNA ligase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of LIG1 mRNA
CTD
PMID:21404309
NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
G
Lmna
lamin A/C
increases metabolic processing affects binding
ISO
Dinitrochlorobenzene results in increased metabolism of LMNA protein Dinitrochlorobenzene binds to LMNA protein
CTD
PMID:29267982 PMID:32991956
NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
G
Lmnb2
lamin B2
affects binding
ISO
Dinitrochlorobenzene binds to LMNB2 protein
CTD
PMID:32991956
NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
G
Ltb
lymphotoxin beta
increases expression
ISO
Dinitrochlorobenzene results in increased expression of LTB mRNA
CTD
PMID:19647056
NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
G
Maff
MAF bZIP transcription factor F
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MAFF mRNA
CTD
PMID:20491607 PMID:20566472
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
G
Mafg
MAF bZIP transcription factor G
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MAFG mRNA
CTD
PMID:20566472
NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
G
Mafk
MAF bZIP transcription factor K
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MAFK mRNA
CTD
PMID:17374397 PMID:20566472
NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048 Ensembl chr12:14,833,984...14,837,048
G
Maip1
matrix AAA peptidase interacting protein 1
affects binding
ISO
Dinitrochlorobenzene binds to MAIP1 protein
CTD
PMID:32991956
NCBI chr 9:58,978,901...58,986,831
Ensembl chr 9:58,978,716...58,986,829
G
Map2k2
mitogen activated protein kinase kinase 2
affects binding
ISO
Dinitrochlorobenzene binds to MAP2K2 protein
CTD
PMID:32991956
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
G
Map3k1
mitogen-activated protein kinase kinase kinase 1
affects binding
ISO
Dinitrochlorobenzene binds to MAP3K1 protein
CTD
PMID:32991956
NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
G
Mapk1
mitogen activated protein kinase 1
multiple interactions decreases phosphorylation
ISO
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK1 protein]; SB 203580 inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK1 protein]
CTD
PMID:18495191
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk12
mitogen-activated protein kinase 12
decreases methylation
ISO
Dinitrochlorobenzene results in decreased methylation of MAPK12 promoter
CTD
PMID:24675093
NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664
G
Mapk14
mitogen activated protein kinase 14
increases phosphorylation affects binding
ISO
Dinitrochlorobenzene results in increased phosphorylation of MAPK14 protein Dinitrochlorobenzene binds to MAPK14 protein
CTD
PMID:15737199 PMID:32991956
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
G
Mapk3
mitogen activated protein kinase 3
multiple interactions decreases phosphorylation
ISO
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK3 protein]; SB 203580 inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK3 protein]
CTD
PMID:18495191
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Mapk8
mitogen-activated protein kinase 8
increases phosphorylation
ISO
Dinitrochlorobenzene results in increased phosphorylation of MAPK8 protein
CTD
PMID:18495191
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
G
Marcks
myristoylated alanine rich protein kinase C substrate
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MARCKS mRNA
CTD
PMID:16314067
NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
G
Mccc2
methylcrotonyl-CoA carboxylase subunit 2
affects binding
ISO
Dinitrochlorobenzene binds to MCCC2 protein
CTD
PMID:32991956
NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972
G
Mcf2
MCF.2 cell line derived transforming sequence
affects binding
ISO
Dinitrochlorobenzene binds to MCF2 protein
CTD
PMID:32991956
NCBI chr X:138,414,077...138,514,828
Ensembl chr X:138,409,256...138,514,446
G
Mcf2l
MCF.2 cell line derived transforming sequence-like
affects binding
ISO
Dinitrochlorobenzene binds to MCF2L protein
CTD
PMID:32991956
NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733
G
Mcm2
minichromosome maintenance complex component 2
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of MCM2 mRNA Dinitrochlorobenzene binds to MCM2 protein
CTD
PMID:21404309 PMID:32991956
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
G
Mcm3
minichromosome maintenance complex component 3
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of MCM3 mRNA Dinitrochlorobenzene binds to MCM3 protein
CTD
PMID:21404309 PMID:32991956
NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
G
Mcm4
minichromosome maintenance complex component 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MCM4 mRNA
CTD
PMID:21404309
NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
G
Mcm5
minichromosome maintenance complex component 5
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of MCM5 mRNA Dinitrochlorobenzene binds to MCM5 protein
CTD
PMID:21404309 PMID:32991956
NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
G
Mcm6
minichromosome maintenance complex component 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MCM6 mRNA
CTD
PMID:21404309
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
G
Mcm7
minichromosome maintenance complex component 7
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MCM7 mRNA
CTD
PMID:21404309
NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
G
Mcts1
MCTS1, re-initiation and release factor
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MCTS1 mRNA
CTD
PMID:17374397
NCBI chr X:117,350,723...117,362,504
Ensembl chr X:117,350,889...117,362,504
G
Mdh2
malate dehydrogenase 2
affects binding
ISO
Dinitrochlorobenzene binds to MDH2 protein
CTD
PMID:32991956
NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
G
Me1
malic enzyme 1
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of ME1 mRNA Dinitrochlorobenzene binds to ME1 protein
CTD
PMID:20566472 PMID:32991956
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
G
Mgmt
O-6-methylguanine-DNA methyltransferase
affects binding
ISO
Dinitrochlorobenzene binds to MGMT protein
CTD
PMID:12974631
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
G
Mgst1
microsomal glutathione S-transferase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MGST1 mRNA
CTD
PMID:20566472
NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
G
Mink1
misshapen-like kinase 1
affects binding
ISO
Dinitrochlorobenzene binds to MINK1 protein
CTD
PMID:32991956
NCBI chr10:55,278,293...55,330,782
Ensembl chr10:55,278,391...55,330,782
G
Mki67
marker of proliferation Ki-67
affects expression affects binding
ISO
Dinitrochlorobenzene affects the expression of MKI67 mRNA Dinitrochlorobenzene binds to MKI67 protein
CTD
PMID:22302311 PMID:32991956
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
G
Mmp1
matrix metallopeptidase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MMP1 mRNA
CTD
PMID:20146380
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
G
Mmp10
matrix metallopeptidase 10
affects expression
ISO
Dinitrochlorobenzene affects the expression of MMP10 mRNA
CTD
PMID:22302311
NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
G
Mmp12
matrix metallopeptidase 12
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MMP12 mRNA
CTD
PMID:10216232
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
G
Mmp3
matrix metallopeptidase 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MMP3 mRNA
CTD
PMID:20146380
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
G
Mob1a
MOB kinase activator 1A
affects binding
ISO
Dinitrochlorobenzene binds to MOB1A protein
CTD
PMID:32991956
NCBI chr 4:115,831,581...115,848,561
Ensembl chr 4:115,831,551...115,848,561
G
Mob1b
MOB kinase activator 1B
affects binding
ISO
Dinitrochlorobenzene binds to MOB1B protein
CTD
PMID:32991956
NCBI chr14:19,333,058...19,365,845
Ensembl chr14:19,332,459...19,365,845
G
Mpo
myeloperoxidase
multiple interactions decreases activity decreases expression
EXP ISO
Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein]; Sulfasalazine inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein] Dinitrochlorobenzene results in decreased expression of MPO mRNA
CTD
PMID:17373747 PMID:17374397
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
G
Mrpl28
mitochondrial ribosomal protein L28
affects binding
ISO
Dinitrochlorobenzene binds to MRPL28 protein
CTD
PMID:32991956
NCBI chr10:15,148,698...15,151,581
Ensembl chr10:15,148,681...15,151,581
G
Mrpl35
mitochondrial ribosomal protein L35
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MRPL35 mRNA
CTD
PMID:17374397
NCBI chr 4:103,865,812...103,876,687
Ensembl chr 4:103,865,812...103,880,887
G
Mrps5
mitochondrial ribosomal protein S5
affects binding
ISO
Dinitrochlorobenzene binds to MRPS5 protein
CTD
PMID:32991956
NCBI chr 3:114,821,046...114,837,291
Ensembl chr 3:114,821,046...114,837,291
G
Mrps6
mitochondrial ribosomal protein S6
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MRPS6 mRNA
CTD
PMID:17374397
NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484
G
Ms4a7
membrane spanning 4-domains A7
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MS4A7 mRNA
CTD
PMID:17374397
NCBI chr 1:207,969,117...207,984,743
Ensembl chr 1:207,968,761...207,983,260
G
Msh2
mutS homolog 2
affects binding
ISO
Dinitrochlorobenzene binds to MSH2 protein
CTD
PMID:32991956
NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
G
Msh6
mutS homolog 6
affects binding
ISO
Dinitrochlorobenzene binds to MSH6 protein
CTD
PMID:32991956
NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
G
Msn
moesin
affects binding
ISO
Dinitrochlorobenzene binds to MSN protein
CTD
PMID:32991956
NCBI chr X:60,996,043...61,064,011
Ensembl chr X:60,995,951...61,065,628
G
Mt2A
metallothionein 2A
increases expression
ISO
Dinitrochlorobenzene results in increased expression of MT2A mRNA
CTD
PMID:20491607
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
G
Mtap
methylthioadenosine phosphorylase
affects binding
ISO
Dinitrochlorobenzene binds to MTAP protein
CTD
PMID:32991956
NCBI chr 5:103,874,460...103,920,684
Ensembl chr 5:103,873,020...103,939,406
G
Mtbp
MDM2 binding protein
affects binding
ISO
Dinitrochlorobenzene binds to MTBP protein
CTD
PMID:32991956
NCBI chr 7:86,973,215...87,055,775
Ensembl chr 7:86,973,069...87,050,827
G
Mthfd1
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to MTHFD1 protein
CTD
PMID:32991956
NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
G
Myb
MYB proto-oncogene, transcription factor
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MYB mRNA
CTD
PMID:17374397
NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
G
Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of MYC mRNA
CTD
PMID:17374397
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
G
Myh11
myosin heavy chain 11
affects binding
ISO
Dinitrochlorobenzene binds to MYH11 protein
CTD
PMID:32991956
NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459
G
Myh9
myosin, heavy chain 9
increases metabolic processing affects binding
ISO
Dinitrochlorobenzene results in increased metabolism of MYH9 protein Dinitrochlorobenzene binds to MYH9 protein
CTD
PMID:29267982 PMID:32991956
NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
G
Myl6b
myosin light chain 6B
affects binding
ISO
Dinitrochlorobenzene binds to MYL6B protein
CTD
PMID:32991956
NCBI chr X:40,572,012...40,572,991
G
Myo1b
myosin Ib
affects binding
ISO
Dinitrochlorobenzene binds to MYO1B protein
CTD
PMID:32991956
NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
G
Myo1d
myosin ID
affects binding
ISO
Dinitrochlorobenzene binds to MYO1D protein
CTD
PMID:32991956
NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349
G
Myo1e
myosin IE
affects binding
ISO
Dinitrochlorobenzene binds to MYO1E protein
CTD
PMID:32991956
NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169
G
Nae1
NEDD8 activating enzyme E1 subunit 1
affects binding
ISO
Dinitrochlorobenzene binds to NAE1 protein
CTD
PMID:32991956
NCBI chr19:446,015...472,145
Ensembl chr19:446,000...472,371
G
Nagk
N-acetylglucosamine kinase
affects binding
ISO
Dinitrochlorobenzene binds to NAGK protein
CTD
PMID:32991956
NCBI chr 4:116,281,179...116,293,870
Ensembl chr 4:116,281,328...116,313,137
G
Nampt
nicotinamide phosphoribosyltransferase
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of NAMPT mRNA Dinitrochlorobenzene binds to NAMPT protein
CTD
PMID:17374397 PMID:19371601 PMID:32991956
NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
G
Naprt
nicotinate phosphoribosyltransferase
affects binding
ISO
Dinitrochlorobenzene binds to NAPRT protein
CTD
PMID:32991956
NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102
G
Ndrg3
NDRG family member 3
affects binding
ISO
Dinitrochlorobenzene binds to NDRG3 protein
CTD
PMID:32991956
NCBI chr 3:145,587,505...145,650,896
Ensembl chr 3:145,548,041...145,650,873
G
Ndufa2
NADH:ubiquinone oxidoreductase subunit A2
affects binding
ISO
Dinitrochlorobenzene binds to NDUFA2 protein
CTD
PMID:32991956
NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076
G
Nefh
neurofilament heavy chain
affects binding
ISO
Dinitrochlorobenzene binds to NEFH protein
CTD
PMID:32991956
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
G
Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions affects response to substance increases expression affects expression decreases expression
ISO
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of NFE2L2 protein]; Dinitrochlorobenzene affects the localization of and results in increased activity of NFE2L2 protein; NFE2L2 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of DNAJB4 mRNA]; NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of GCLM mRNA] Dinitrochlorobenzene affects the localization of and results in increased activity of NFE2L2 protein; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in decreased abundance of Glutathione]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased abundance of Reactive Oxygen Species]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL3 mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL1 mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL10 mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL1B mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of BCL2 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of CAT mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX1 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX2 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX5 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX6 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GSR mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of NOS2 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of NFE2L2 mRNA] [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Dinitrochlorobenzene; NFE2L2 affects the susceptibility to Dinitrochlorobenzene Dinitrochlorobenzene affects the expression of NFE2L2 protein
CTD
PMID:18785192 PMID:19033392 PMID:19303893 PMID:19427879 PMID:23564646 PMID:26022718 PMID:26244607 PMID:27492222 PMID:27965148 PMID:28219650 PMID:31967339 PMID:34651546 More...
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nfkb1
nuclear factor kappa B subunit 1
decreases expression affects expression multiple interactions increases expression
ISO
Dinitrochlorobenzene results in decreased expression of NFKB1 mRNA Dinitrochlorobenzene affects the expression of NFKB1 mRNA sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of NFKB1 mRNA]
CTD
PMID:20385217 PMID:28219650 PMID:34651546
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
G
Ninj1
ninjurin 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of NINJ1 mRNA
CTD
PMID:16314067 PMID:17374397
NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
G
Nlrp12
NLR family, pyrin domain containing 12
decreases expression multiple interactions
ISO
Dinitrochlorobenzene results in decreased expression of NLRP12 protein Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein]; Dinitrochlorobenzene results in decreased expression of and affects the localization of NLRP12 protein
CTD
PMID:27585668 PMID:31276767
NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934
G
Nlrp3
NLR family, pyrin domain containing 3
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of NLRP3 protein Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein]
CTD
PMID:31276767
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
G
Nolc1
nucleolar and coiled-body phosphoprotein 1
affects binding
ISO
Dinitrochlorobenzene binds to NOLC1 protein
CTD
PMID:32991956
NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
G
Nop2
NOP2 nucleolar protein
affects binding
ISO
Dinitrochlorobenzene binds to NOP2 protein
CTD
PMID:32991956
NCBI chr 4:157,932,731...157,944,462
Ensembl chr 4:157,932,716...157,944,459
G
Nos2
nitric oxide synthase 2
multiple interactions increases expression affects expression
EXP ISO
Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased expression of NOS2 protein] Dinitrochlorobenzene results in increased expression of NOS2 protein NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of NOS2 mRNA] Dinitrochlorobenzene affects the expression of NOS2 mRNA
CTD
PMID:17373747 PMID:28219650
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Npr3
natriuretic peptide receptor 3
affects expression
ISO
Dinitrochlorobenzene affects the expression of NPR3 mRNA
CTD
PMID:19527780
NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
G
Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of NQO1 mRNA]
CTD
PMID:16314067 PMID:19033392 PMID:20146380 PMID:20491607 PMID:20566472 PMID:28219650 More...
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nr0b1
nuclear receptor subfamily 0, group B, member 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of NR0B1 mRNA
CTD
PMID:20146380
NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of NR3C1 mRNA
CTD
PMID:17374397
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Nrdc
nardilysin convertase
affects binding
ISO
Dinitrochlorobenzene binds to NRDC protein
CTD
PMID:32991956
NCBI chr 5:123,755,807...123,818,910
Ensembl chr 5:123,755,806...123,818,595
G
Nrep
neuronal regeneration related protein
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of NREP mRNA
CTD
PMID:17374397
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
G
Nrf1
nuclear respiratory factor 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of NRF1 mRNA
CTD
PMID:28219650
NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
G
Nsdhl
NAD(P) dependent steroid dehydrogenase-like
affects binding
ISO
Dinitrochlorobenzene binds to NSDHL protein
CTD
PMID:32991956
NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
G
Nt5dc1
5'-nucleotidase domain containing 1
affects binding
ISO
Dinitrochlorobenzene binds to NT5DC1 protein
CTD
PMID:32991956
NCBI chr20:38,105,677...38,208,613
Ensembl chr20:38,105,678...38,208,591
G
Numa1
nuclear mitotic apparatus protein 1
affects binding
ISO
Dinitrochlorobenzene binds to NUMA1 protein
CTD
PMID:32991956
NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855
G
Nup155
nucleoporin 155
affects binding
ISO
Dinitrochlorobenzene binds to NUP155 protein
CTD
PMID:32991956
NCBI chr 2:57,201,310...57,252,918
Ensembl chr 2:57,201,272...57,254,148
G
Nup205
nucleoporin 205
affects binding
ISO
Dinitrochlorobenzene binds to NUP205 protein
CTD
PMID:32991956
NCBI chr 4:63,854,934...63,920,852
Ensembl chr 4:63,854,783...63,920,844
G
Nup43
nucleoporin 43
increases methylation
ISO
Dinitrochlorobenzene results in increased methylation of NUP43 promoter
CTD
PMID:24675093
NCBI chr 1:2,144,427...2,157,887
Ensembl chr 1:2,148,043...2,158,186
G
Nup88
nucleoporin 88
increases expression
ISO
Dinitrochlorobenzene results in increased expression of NUP88 mRNA
CTD
PMID:17374397
NCBI chr10:55,667,903...55,692,249
Ensembl chr10:55,667,906...55,692,257
G
Odc1
ornithine decarboxylase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ODC1 mRNA
CTD
PMID:21404309
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
G
Ola1
Obg-like ATPase 1
affects binding
ISO
Dinitrochlorobenzene binds to OLA1 protein
CTD
PMID:32991956
NCBI chr 3:57,966,896...58,085,955
Ensembl chr 3:57,966,896...58,084,480
G
Orc1
origin recognition complex, subunit 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ORC1 mRNA
CTD
PMID:21404309
NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
G
Orc5
origin recognition complex, subunit 5
affects binding
ISO
Dinitrochlorobenzene binds to ORC5 protein
CTD
PMID:32991956
NCBI chr 4:12,548,007...12,612,611
Ensembl chr 4:12,548,007...12,612,568
G
Orc6
origin recognition complex, subunit 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ORC6 mRNA
CTD
PMID:21404309
NCBI chr19:21,757,867...21,765,638
Ensembl chr19:21,757,866...21,765,662
G
Osm
oncostatin M
increases expression
ISO
Dinitrochlorobenzene results in increased expression of OSM mRNA
CTD
PMID:19647056
NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
G
Otud1
OTU deubiquitinase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of OTUD1 mRNA
CTD
PMID:17374397
NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995
G
Oxsr1
oxidative stress responsive kinase 1
affects binding
ISO
Dinitrochlorobenzene binds to OXSR1 protein
CTD
PMID:32991956
NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027
G
P4hb
prolyl 4-hydroxylase subunit beta
affects binding
ISO
Dinitrochlorobenzene binds to P4HB protein
CTD
PMID:32991956
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
G
Padi4
peptidyl arginine deiminase 4
affects binding
ISO
Dinitrochlorobenzene binds to PADI4 protein
CTD
PMID:32991956
NCBI chr 5:153,041,351...153,074,412
Ensembl chr 5:153,041,352...153,074,362
G
Paics
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of PAICS mRNA
CTD
PMID:17374397
NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
G
Papss1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
affects binding
ISO
Dinitrochlorobenzene binds to PAPSS1 protein
CTD
PMID:32991956
NCBI chr 2:220,040,343...220,114,399
Ensembl chr 2:220,040,312...220,114,395
G
Parp1
poly (ADP-ribose) polymerase 1
affects binding
ISO
Dinitrochlorobenzene binds to PARP1 protein
CTD
PMID:32991956
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
G
Pcna
proliferating cell nuclear antigen
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PCNA mRNA
CTD
PMID:21404309
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
G
Pcsk9
proprotein convertase subtilisin/kexin type 9
affects binding
ISO
Dinitrochlorobenzene binds to PCSK9 protein
CTD
PMID:32991956
NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
G
Pde4b
phosphodiesterase 4B
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PDE4B mRNA
CTD
PMID:17374397
NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
G
Pde4d
phosphodiesterase 4D
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PDE4D mRNA
CTD
PMID:17374397
NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
G
Pdhb
pyruvate dehydrogenase E1 subunit beta
affects binding
ISO
Dinitrochlorobenzene binds to PDHB protein
CTD
PMID:32991956
NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
G
Pdia4
protein disulfide isomerase family A, member 4
affects binding
ISO
Dinitrochlorobenzene binds to PDIA4 protein
CTD
PMID:32991956
NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
G
Pds5b
PDS5 cohesin associated factor B
affects binding
ISO
Dinitrochlorobenzene binds to PDS5B protein
CTD
PMID:32991956
NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596
G
Pf4
platelet factor 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PF4 mRNA
CTD
PMID:19647056
NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
G
Pfkl
phosphofructokinase, liver type
affects binding
ISO
Dinitrochlorobenzene binds to PFKL protein
CTD
PMID:32991956
NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315
G
Pgd
phosphogluconate dehydrogenase
increases expression affects binding
ISO
Dinitrochlorobenzene results in increased expression of PGD mRNA Dinitrochlorobenzene binds to PGD protein
CTD
PMID:20566472 PMID:32991956
NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
G
Phf11
PHD finger protein 11
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PHF11 mRNA
CTD
PMID:19647056
NCBI chr15:33,390,290...33,414,647
Ensembl chr15:33,390,292...33,413,009
G
Phlda1
pleckstrin homology-like domain, family A, member 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PHLDA1 mRNA
CTD
PMID:17374397
NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
G
Picalm
phosphatidylinositol binding clathrin assembly protein
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PICALM mRNA
CTD
PMID:17374397
NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
G
Pir
pirin
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PIR mRNA
CTD
PMID:16314067
NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218
G
Pkm
pyruvate kinase M1/2
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of PKM protein
CTD
PMID:29267982
NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
G
Plat
plasminogen activator, tissue type
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PLAT mRNA
CTD
PMID:17374397
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
G
Plekhm3
pleckstrin homology domain containing M3
increases methylation
ISO
Dinitrochlorobenzene results in increased methylation of PLEKHM3 promoter
CTD
PMID:24675093
NCBI chr 9:66,166,233...66,325,332
Ensembl chr 9:66,166,321...66,325,294
G
Plin2
perilipin 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PLIN2 mRNA
CTD
PMID:16314067
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
G
Plk1
polo-like kinase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PLK1 mRNA
CTD
PMID:21404309
NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
G
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PMAIP1 mRNA
CTD
PMID:20713136
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
G
Pola1
DNA polymerase alpha 1, catalytic subunit
increases expression
ISO
Dinitrochlorobenzene results in increased expression of POLA1 mRNA
CTD
PMID:21404309
NCBI chr X:58,034,617...58,348,612
Ensembl chr X:58,034,619...58,348,536
G
Pold3
DNA polymerase delta 3, accessory subunit
increases expression
ISO
Dinitrochlorobenzene results in increased expression of POLD3 mRNA
CTD
PMID:21404309
NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665
G
Pole
DNA polymerase epsilon, catalytic subunit
increases expression
ISO
Dinitrochlorobenzene results in increased expression of POLE mRNA
CTD
PMID:21404309
NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939
G
Polr2a
RNA polymerase II subunit A
affects binding
ISO
Dinitrochlorobenzene binds to POLR2A protein
CTD
PMID:32991956
NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
G
Ppa1
inorganic pyrophosphatase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PPA1 mRNA
CTD
PMID:18242016
NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215
G
Ppbp
pro-platelet basic protein
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PPBP mRNA
CTD
PMID:19647056
NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
G
Ppif
peptidylprolyl isomerase F
increases oxidation
ISO
Dinitrochlorobenzene results in increased oxidation of PPIF protein
CTD
PMID:26975474
NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
G
Ppl
periplakin
affects binding
ISO
Dinitrochlorobenzene binds to PPL protein
CTD
PMID:32991956
NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575
G
Ppp1ca
protein phosphatase 1 catalytic subunit alpha
affects binding
ISO
Dinitrochlorobenzene binds to PPP1CA protein
CTD
PMID:32991956
NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
G
Ppp2r1b
protein phosphatase 2 scaffold subunit A beta
affects binding
ISO
Dinitrochlorobenzene binds to PPP2R1B protein
CTD
PMID:32991956
NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
G
Ppp2r5c
protein phosphatase 2, regulatory subunit B', gamma
affects binding
ISO
Dinitrochlorobenzene binds to PPP2R5C protein
CTD
PMID:32991956
NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346
G
Ppp3ca
protein phosphatase 3 catalytic subunit alpha
affects binding
ISO
Dinitrochlorobenzene binds to PPP3CA protein
CTD
PMID:32991956
NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
G
Ppt1
palmitoyl-protein thioesterase 1
affects binding
ISO
Dinitrochlorobenzene binds to PPT1 protein
CTD
PMID:32991956
NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048
G
Ppwd1
peptidylprolyl isomerase domain and WD repeat containing 1
affects binding
ISO
Dinitrochlorobenzene binds to PPWD1 protein
CTD
PMID:32991956
NCBI chr 2:35,337,301...35,360,661
Ensembl chr 2:35,335,962...35,360,460
G
Prdm1
PR/SET domain 1
multiple interactions increases expression
ISO
BAY 11-7085 inhibits the reaction [Dinitrochlorobenzene results in increased expression of PRDM1 mRNA]; BAY 11-7085 inhibits the reaction [Dinitrochlorobenzene results in increased expression of PRDM1 protein]; PRDM1 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of IL18 protein] Dinitrochlorobenzene results in increased expression of PRDM1 mRNA; Dinitrochlorobenzene results in increased expression of PRDM1 protein
CTD
PMID:27585668 PMID:31276767
NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
G
Prdx1
peroxiredoxin 1
affects oxidation affects binding
ISO
Dinitrochlorobenzene affects the oxidation of PRDX1 protein Dinitrochlorobenzene binds to PRDX1 protein
CTD
PMID:18789312 PMID:32991956
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
G
Prdx2
peroxiredoxin 2
increases oxidation
ISO
Dinitrochlorobenzene results in increased oxidation of PRDX2 protein
CTD
PMID:18789312
NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
G
Prdx3
peroxiredoxin 3
decreases expression increases oxidation
ISO
Dinitrochlorobenzene results in decreased expression of PRDX3 mRNA Dinitrochlorobenzene results in increased oxidation of PRDX3 protein
CTD
PMID:17374397 PMID:18789312 PMID:26975474
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
G
Prim1
DNA primase subunit 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PRIM1 mRNA
CTD
PMID:21404309
NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526
G
Prkar1a
protein kinase cAMP-dependent type I regulatory subunit alpha
affects binding
ISO
Dinitrochlorobenzene binds to PRKAR1A protein
CTD
PMID:32991956
NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041
G
Prkcb
protein kinase C, beta
affects localization
ISO
Dinitrochlorobenzene affects the localization of PRKCB protein
CTD
PMID:24136171
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
G
Prkdc
protein kinase, DNA-activated, catalytic subunit
affects binding
ISO
Dinitrochlorobenzene binds to PRKDC protein
CTD
PMID:32991956
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
G
Prpf6
pre-mRNA processing factor 6
affects binding
ISO
Dinitrochlorobenzene binds to PRPF6 protein
CTD
PMID:32991956
NCBI chr 3:168,706,952...168,771,191
Ensembl chr 3:168,704,299...168,774,991
G
Psap
prosaposin
affects binding
ISO
Dinitrochlorobenzene binds to PSAP protein
CTD
PMID:32991956
NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498
G
Psma5
proteasome 20S subunit alpha 5
decreases expression affects binding
ISO
Dinitrochlorobenzene results in decreased expression of PSMA5 mRNA Dinitrochlorobenzene binds to PSMA5 protein
CTD
PMID:17374397 PMID:32991956
NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
G
Psmc5
proteasome 26S subunit, ATPase 5
affects binding
ISO
Dinitrochlorobenzene binds to PSMC5 protein
CTD
PMID:32991956
NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
G
Psmd11
proteasome 26S subunit, non-ATPase 11
affects binding
ISO
Dinitrochlorobenzene binds to PSMD11 protein
CTD
PMID:32991956
NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766
G
Psmd5
proteasome 26S subunit, non-ATPase 5
affects binding
ISO
Dinitrochlorobenzene binds to PSMD5 protein
CTD
PMID:32991956
NCBI chr 3:18,133,715...18,151,000
Ensembl chr 3:18,133,717...18,151,029
G
Psmd6
proteasome 26S subunit, non-ATPase 6
affects binding
ISO
Dinitrochlorobenzene binds to PSMD6 protein
CTD
PMID:32991956
NCBI chr15:11,102,174...11,112,180
Ensembl chr15:11,102,180...11,205,620
G
Psme4
proteasome activator subunit 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PSME4 mRNA
CTD
PMID:21404309
NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408
G
Ptcra
pre T-cell antigen receptor alpha
affects expression
ISO
Dinitrochlorobenzene affects the expression of PTCRA mRNA
CTD
PMID:22302311
NCBI chr 9:14,218,907...14,229,141
Ensembl chr 9:14,218,802...14,229,235
G
Ptger3
prostaglandin E receptor 3
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of PTGER3 mRNA
CTD
PMID:17374397
NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
G
Ptgr1
prostaglandin reductase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PTGR1 mRNA
CTD
PMID:20566472
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
G
Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PTGS2 mRNA
CTD
PMID:19371601 PMID:20146380
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptpn1
protein tyrosine phosphatase, non-receptor type 1
affects binding
ISO
Dinitrochlorobenzene binds to PTPN1 protein
CTD
PMID:32991956
NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
G
Pttg1
PTTG1 regulator of sister chromatid separation, securin
increases expression
ISO
Dinitrochlorobenzene results in increased expression of PTTG1 mRNA
CTD
PMID:21404309
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
G
Pycard
PYD and CARD domain containing
multiple interactions
ISO
Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein]
CTD
PMID:31276767
NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
G
Pygl
glycogen phosphorylase L
affects binding
ISO
Dinitrochlorobenzene binds to PYGL protein
CTD
PMID:32991956
NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
G
Rab30
RAB30, member RAS oncogene family
affects binding
ISO
Dinitrochlorobenzene binds to RAB30 protein
CTD
PMID:32991956
NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181
G
Rab32
RAB32, member RAS oncogene family
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of RAB32 mRNA
CTD
PMID:17374397
NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934
G
Rad50
RAD50 double strand break repair protein
affects binding
ISO
Dinitrochlorobenzene binds to RAD50 protein
CTD
PMID:32991956
NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
G
Rars1
arginyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to RARS1 protein
CTD
PMID:32991956
NCBI chr10:20,270,744...20,295,192
Ensembl chr10:20,270,483...20,295,196
G
Rasgrp1
RAS guanyl releasing protein 1
affects binding
ISO
Dinitrochlorobenzene binds to RASGRP1 protein
CTD
PMID:32991956
NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
G
Rasl10a
RAS-like, family 10, member A
affects binding
ISO
Dinitrochlorobenzene binds to RASL10A protein
CTD
PMID:32991956
NCBI chr14:79,955,093...79,956,471
Ensembl chr14:79,954,398...79,956,468
G
Rbm17
RNA binding motif protein 17
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of RBM17 mRNA
CTD
PMID:17374397
NCBI chr17:66,937,140...66,954,034
Ensembl chr17:66,937,140...66,954,014
G
Rbm25
RNA binding motif protein 25
affects binding
ISO
Dinitrochlorobenzene binds to RBM25 protein
CTD
PMID:32991956
NCBI chr 6:103,271,775...103,319,090
Ensembl chr 6:103,271,801...103,317,854
G
Rbm26
RNA binding motif protein 26
affects binding
ISO
Dinitrochlorobenzene binds to RBM26 protein
CTD
PMID:32991956
NCBI chr15:81,884,783...81,964,245
Ensembl chr15:81,887,219...81,964,118
G
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of RBPJ mRNA
CTD
PMID:17374397
NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
G
Rcc1
regulator of chromosome condensation 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RCC1 mRNA
CTD
PMID:18242016
NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577
G
Rdx
radixin
affects binding
ISO
Dinitrochlorobenzene binds to RDX protein
CTD
PMID:32991956
NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
G
Recql4
RecQ like helicase 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RECQL4 mRNA
CTD
PMID:18242016
NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions increases phosphorylation
ISO
aristolochic acid I inhibits the reaction [Dinitrochlorobenzene results in increased phosphorylation of RELA protein]; TLR4 protein promotes the reaction [Dinitrochlorobenzene results in increased phosphorylation of RELA protein]
CTD
PMID:31226360
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Rfc3
replication factor C subunit 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RFC3 mRNA
CTD
PMID:21404309
NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778
G
Rfc4
replication factor C subunit 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RFC4 mRNA
CTD
PMID:21404309
NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122
G
Rfc5
replication factor C subunit 5
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RFC5 mRNA
CTD
PMID:21404309
NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
G
Rgs1
regulator of G-protein signaling 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RGS1 mRNA
CTD
PMID:17374397
NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984
G
Rgs2
regulator of G-protein signaling 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RGS2 mRNA
CTD
PMID:20146380
NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
G
Rgs21
regulator of G-protein signaling 21
affects binding
ISO
Dinitrochlorobenzene binds to RGS21 protein
CTD
PMID:32991956
NCBI chr13:56,239,448...56,289,290
Ensembl chr13:56,240,735...56,266,573
G
Rhoc
ras homolog family member C
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RHOC mRNA
CTD
PMID:16314067
NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
G
Rnase2
ribonuclease A family member 2
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of RNASE2A mRNA
CTD
PMID:18242016
NCBI chr15:24,449,618...24,450,427
Ensembl chr15:24,449,611...24,450,479
G
Rpl27a
ribosomal protein L27A
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RPL27A mRNA
CTD
PMID:17374397
NCBI chr 1:163,539,732...163,542,771
G
Rpl36
ribosomal protein L36
affects binding
ISO
Dinitrochlorobenzene binds to RPL36 protein
CTD
PMID:32991956
NCBI chr 9:1,441,986...1,447,397
Ensembl chr 6:98,809,534...98,809,897
G
Rpl9
ribosomal protein L9
affects binding
ISO
Dinitrochlorobenzene binds to RPL9 protein
CTD
PMID:32991956
NCBI chr14:42,893,945...42,897,140
Ensembl chr14:42,893,942...42,897,136 Ensembl chr 3:42,893,942...42,897,136
G
Rps6ka1
ribosomal protein S6 kinase A1
affects binding
ISO
Dinitrochlorobenzene binds to RPS6KA1 protein
CTD
PMID:32991956
NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272
G
Rps6ka3
ribosomal protein S6 kinase A3
affects binding
ISO
Dinitrochlorobenzene binds to RPS6KA3 protein
CTD
PMID:32991956
NCBI chr X:35,517,306...35,623,296
Ensembl chr X:35,517,306...35,623,207
G
Rps6ka5
ribosomal protein S6 kinase A5
affects binding
ISO
Dinitrochlorobenzene binds to RPS6KA5 protein
CTD
PMID:32991956
NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
G
Rrm1
ribonucleotide reductase catalytic subunit M1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RRM1 mRNA
CTD
PMID:21404309
NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
G
Rrm2
ribonucleotide reductase regulatory subunit M2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RRM2 mRNA
CTD
PMID:21404309
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
G
Rtn4ip1
reticulon 4 interacting protein 1
affects binding
ISO
Dinitrochlorobenzene binds to RTN4IP1 protein
CTD
PMID:32991956
NCBI chr20:47,382,251...47,422,747
Ensembl chr20:47,382,234...47,422,338
G
Rtp4
receptor (chemosensory) transporter protein 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of RTP4 mRNA
CTD
PMID:18242016 PMID:19647056
NCBI chr11:77,237,341...77,249,194
Ensembl chr11:77,238,216...77,335,437
G
Runx3
RUNX family transcription factor 3
increases expression
EXP
Dinitrochlorobenzene results in increased expression of RUNX3 mRNA
CTD
PMID:21893156
NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156
G
S100a10
S100 calcium binding protein A10
increases expression
ISO
Dinitrochlorobenzene results in increased expression of S100A10 mRNA
CTD
PMID:16314067
NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
G
S100b
S100 calcium binding protein B
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of S100B mRNA
CTD
PMID:17374397
NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
G
Safb
scaffold attachment factor B
affects binding
ISO
Dinitrochlorobenzene binds to SAFB protein
CTD
PMID:32991956
NCBI chr 9:1,417,449...1,438,408
Ensembl chr 9:1,417,525...1,438,644
G
Sat1
spermidine/spermine N1-acetyl transferase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SAT1 mRNA
CTD
PMID:17374397
NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
G
Scyl1
SCY1 like pseudokinase 1
affects binding
ISO
Dinitrochlorobenzene binds to SCYL1 protein
CTD
PMID:32991956
NCBI chr 1:203,045,776...203,059,550
Ensembl chr 1:203,045,741...203,059,533
G
Sdc2
syndecan 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SDC2 mRNA
CTD
PMID:17374397
NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
G
Sdha
succinate dehydrogenase complex flavoprotein subunit A
affects binding
ISO
Dinitrochlorobenzene binds to SDHA protein
CTD
PMID:32991956
NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
G
Sema4c
semaphorin 4C
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SEMA4C mRNA
CTD
PMID:16314067
NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128
G
Serbp1
Serpine1 mRNA binding protein 1
decreases expression affects binding
ISO
Dinitrochlorobenzene results in decreased expression of SERBP1 mRNA Dinitrochlorobenzene binds to SERBP1 protein
CTD
PMID:17374397 PMID:32991956
NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813
G
Serpinb13
serpin family B member 13
affects binding
ISO
Dinitrochlorobenzene binds to SERPINB13 protein
CTD
PMID:32991956
NCBI chr13:23,118,582...23,150,352
Ensembl chr13:23,118,584...23,150,760
G
Serpine1
serpin family E member 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of SERPINE1 mRNA
CTD
PMID:33774146
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
G
Sf3b1
splicing factor 3b, subunit 1
affects binding
ISO
Dinitrochlorobenzene binds to SF3B1 protein
CTD
PMID:32991956
NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300
G
Sf3b3
splicing factor 3b, subunit 3
affects binding
ISO
Dinitrochlorobenzene binds to SF3B3 protein
CTD
PMID:32991956
NCBI chr19:38,782,749...38,820,271
Ensembl chr19:38,783,040...38,820,245
G
Sh2b2
SH2B adaptor protein 2
decreases methylation
ISO
Dinitrochlorobenzene results in decreased methylation of SH2B2 promoter
CTD
PMID:24675093
NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844
G
Si
sucrase-isomaltase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SI mRNA
CTD
PMID:16314067
NCBI chr 2:157,505,893...157,586,228
Ensembl chr 2:157,506,342...157,585,260
G
Skil
SKI-like proto-oncogene
affects binding
ISO
Dinitrochlorobenzene binds to SKIL protein
CTD
PMID:32991956
NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
G
Skp2
S-phase kinase associated protein 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SKP2 mRNA
CTD
PMID:21404309
NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
G
Slamf1
signaling lymphocytic activation molecule family member 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of SLAMF1 mRNA
CTD
PMID:20713136
NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497
G
Slamf8
SLAM family member 8
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of SLAMF8 mRNA
CTD
PMID:17374397
NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211
G
Slc12a9
solute carrier family 12, member 9
decreases methylation
ISO
Dinitrochlorobenzene results in decreased methylation of SLC12A9 promoter
CTD
PMID:24675093
NCBI chr12:19,368,990...19,385,881
Ensembl chr12:19,369,004...19,385,877
G
Slc16a10
solute carrier family 16 member 10
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SLC16A10 mRNA
CTD
PMID:17374397
NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
G
Slc25a5
solute carrier family 25 member 5
affects binding
ISO
Dinitrochlorobenzene binds to SLC25A5 protein
CTD
PMID:32991956
NCBI chr X:116,031,896...116,034,963
Ensembl chr X:116,031,803...116,034,967
G
Slc2a3
solute carrier family 2 member 3
decreases expression increases expression
ISO
Dinitrochlorobenzene results in decreased expression of SLC2A3 mRNA Dinitrochlorobenzene results in increased expression of SLC2A3 mRNA
CTD
PMID:17374397 PMID:19371601
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
G
Slc7a5
solute carrier family 7 member 5
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SLC7A5 mRNA
CTD
PMID:17374397
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
G
Slfn2
schlafen family member 2
affects binding
ISO
Dinitrochlorobenzene binds to SLFN12L protein
CTD
PMID:32991956
NCBI chr10:67,953,322...67,959,659
Ensembl chr10:67,953,171...67,959,458
G
Slpi
secretory leukocyte peptidase inhibitor
affects expression
ISO
Dinitrochlorobenzene affects the expression of SLPI mRNA
CTD
PMID:22302311
NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
G
Smc1a
structural maintenance of chromosomes 1A
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of SMC1A mRNA
CTD
PMID:17374397
NCBI chr X:21,103,323...21,148,053
Ensembl chr X:21,103,282...21,148,056
G
Snai1
snail family transcriptional repressor 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SNAI1 mRNA
CTD
PMID:20146380
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
G
Snu13
small nuclear ribonucleoprotein 13
affects binding
ISO
Dinitrochlorobenzene binds to SNU13 protein
CTD
PMID:32991956
NCBI chr 7:113,565,293...113,570,887
Ensembl chr 7:113,565,295...113,570,872 Ensembl chr 1:113,565,295...113,570,872
G
Snx15
sorting nexin 15
increases methylation
ISO
Dinitrochlorobenzene results in increased methylation of SNX15 promoter
CTD
PMID:24675093
NCBI chr 1:203,417,029...203,426,173
Ensembl chr 1:203,417,029...203,426,247
G
Snx2
sorting nexin 2
affects binding
ISO
Dinitrochlorobenzene binds to SNX2 protein
CTD
PMID:32991956
NCBI chr18:46,602,223...46,643,870
Ensembl chr18:46,602,284...46,643,865
G
Snx9
sorting nexin 9
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SNX9 mRNA
CTD
PMID:17374397
NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036
G
Sod1
superoxide dismutase 1
increases expression decreases expression
ISO
Dinitrochlorobenzene results in increased expression of SOD1 mRNA Dinitrochlorobenzene results in decreased expression of SOD1 mRNA
CTD
PMID:20566472 PMID:28219650
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
G
Sod2
superoxide dismutase 2
increases expression multiple interactions decreases expression
ISO
Dinitrochlorobenzene results in increased expression of SOD2 mRNA Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 protein] Dinitrochlorobenzene results in decreased expression of SOD2 mRNA
CTD
PMID:7476933 PMID:16314067 PMID:20566472 PMID:28219650
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Sod3
superoxide dismutase 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SOD3 mRNA
CTD
PMID:20566472
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
G
Spp1
secreted phosphoprotein 1
multiple interactions
EXP
Dinitrochlorobenzene inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; Dinitrochlorobenzene inhibits the reaction [8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; Dinitrochlorobenzene inhibits the reaction [Dipyridamole inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]
CTD
PMID:20453393
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
G
Spta1
spectrin, alpha, erythrocytic 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SPTA1 mRNA
CTD
PMID:16314067
NCBI chr13:86,203,504...86,279,371
Ensembl chr13:86,203,504...86,279,371
G
Sqle
squalene epoxidase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SQLE mRNA
CTD
PMID:18242016
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
G
Srm
spermidine synthase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SRM mRNA
CTD
PMID:21404309
NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
G
Srp72
signal recognition particle 72
decreases expression affects binding
ISO
Dinitrochlorobenzene results in decreased expression of SRP72 mRNA Dinitrochlorobenzene binds to SRP72 protein
CTD
PMID:17374397 PMID:32991956
NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729
G
Srrm1
serine and arginine repetitive matrix 1
affects binding
ISO
Dinitrochlorobenzene binds to SRRM1 protein
CTD
PMID:32991956
NCBI chr 5:147,559,515...147,591,895
Ensembl chr 5:147,559,514...147,591,849
G
Srsf9
serine and arginine rich splicing factor 9
affects binding
ISO
Dinitrochlorobenzene binds to SRSF9 protein
CTD
PMID:32991956
NCBI chr12:41,278,225...41,284,502
Ensembl chr12:41,275,687...41,284,499
G
Srxn1
sulfiredoxin 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of SRXN1 mRNA
CTD
PMID:20566472 PMID:25236440
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
G
Stat1
signal transducer and activator of transcription 1
decreases expression affects binding
ISO
Dinitrochlorobenzene results in decreased expression of STAT1 mRNA Dinitrochlorobenzene binds to STAT1 protein
CTD
PMID:17374397 PMID:32991956
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
G
Stat4
signal transducer and activator of transcription 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of STAT4 mRNA
CTD
PMID:17374397
NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540
G
Stat5b
signal transducer and activator of transcription 5B
increases expression
ISO
Dinitrochlorobenzene results in increased expression of STAT5B mRNA
CTD
PMID:17374397
NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
G
Stau1
staufen double-stranded RNA binding protein 1
affects binding
ISO
Dinitrochlorobenzene binds to STAU1 protein
CTD
PMID:32991956
NCBI chr 3:155,680,000...155,725,969
Ensembl chr 3:155,680,000...155,725,909
G
Stip1
stress-induced phosphoprotein 1
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of STIP1 protein
CTD
PMID:29267982
NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476
G
Stx11
syntaxin 11
increases expression
ISO
Dinitrochlorobenzene results in increased expression of STX11 mRNA
CTD
PMID:17374397
NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
G
Supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
affects binding
ISO
Dinitrochlorobenzene binds to SUPT16H protein
CTD
PMID:32991956
NCBI chr15:24,867,697...24,904,818
Ensembl chr15:24,866,489...24,904,846
G
Tars1
threonyl-tRNA synthetase 1
affects binding
ISO
Dinitrochlorobenzene binds to TARS1 protein
CTD
PMID:32991956
NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717
G
Tbc1d4
TBC1 domain family, member 4
affects binding
ISO
Dinitrochlorobenzene binds to TBC1D4 protein
CTD
PMID:32991956
NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
G
Tex15
testis expressed 15, meiosis and synapsis associated
affects binding
ISO
Dinitrochlorobenzene binds to TEX15 protein
CTD
PMID:32991956
NCBI chr16:58,598,991...58,659,005
Ensembl chr16:58,598,989...58,658,467
G
Tfdp1
transcription factor Dp-1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TFDP1 mRNA
CTD
PMID:18242016 PMID:21404309
NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
G
Tfec
transcription factor EC
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TFEC mRNA
CTD
PMID:19647056
NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236
G
Tgif1
TGFB-induced factor homeobox 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TGIF1 mRNA
CTD
PMID:17374397
NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
G
Thbs1
thrombospondin 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of THBS1 mRNA
CTD
PMID:22302311
NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
G
Thbs4
thrombospondin 4
affects expression
ISO
Dinitrochlorobenzene affects the expression of THBS4 mRNA
CTD
PMID:22302311
NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
G
Timd2
T-cell immunoglobulin and mucin domain containing 2
affects expression
ISO
Dinitrochlorobenzene affects the expression of TIMD2 mRNA
CTD
PMID:22302311
NCBI chr10:31,060,308...31,101,262
Ensembl chr10:31,060,326...31,094,623
G
Timm10b
translocase of inner mitochondrial membrane 10B
affects binding
ISO
Dinitrochlorobenzene binds to TIMM10B protein
CTD
PMID:32991956
NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642
G
Timp1
TIMP metallopeptidase inhibitor 1
affects expression
ISO
Dinitrochlorobenzene affects the expression of TIMP1 mRNA
CTD
PMID:22302311
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
G
Timp3
TIMP metallopeptidase inhibitor 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TIMP3 mRNA
CTD
PMID:16314067
NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
G
Tk1
thymidine kinase 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TK1 mRNA
CTD
PMID:21404309
NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
G
Tkt
transketolase
increases metabolic processing
ISO
Dinitrochlorobenzene results in increased metabolism of TKT protein
CTD
PMID:29267982
NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
G
Tlr4
toll-like receptor 4
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of TLR4 mRNA; Dinitrochlorobenzene results in increased expression of TLR4 protein TLR4 protein promotes the reaction [Dinitrochlorobenzene results in increased phosphorylation of RELA protein]
CTD
PMID:31226360
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
G
Tmpo
thymopoietin
affects binding
ISO
Dinitrochlorobenzene binds to TMPO protein
CTD
PMID:32991956
NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
G
Tnf
tumor necrosis factor
multiple interactions increases expression affects expression increases secretion
ISO
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TNF mRNA; [Dacarbazine co-treated with Dinitrochlorobenzene] results in increased expression of TNF mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; Dinitrochlorobenzene inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Lipopolysaccharides promotes the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TNF mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF protein] Dinitrochlorobenzene results in increased expression of TNF mRNA; Dinitrochlorobenzene results in increased expression of TNF protein [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of TNF protein; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; TNF protein affects the reaction [Dinitrochlorobenzene results in increased expression of CCR7 mRNA] Dinitrochlorobenzene affects the expression of TNF mRNA Dinitrochlorobenzene results in increased secretion of TNF protein
CTD
PMID:7476933 PMID:12202904 PMID:15304089 PMID:16675337 PMID:16687389 PMID:17118622 PMID:18495191 PMID:19647056 PMID:20385217 PMID:20417223 PMID:21782934 PMID:22245253 PMID:23200891 PMID:23454147 PMID:23499868 PMID:24964617 PMID:28826779 PMID:34651546 More...
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tnfaip3
TNF alpha induced protein 3
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TNFAIP3 mRNA
CTD
PMID:20146380
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
G
Tnfaip6
TNF alpha induced protein 6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TNFAIP6 mRNA
CTD
PMID:17374397
NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
G
Tnfrsf12a
TNF receptor superfamily member 12A
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TNFRSF12A mRNA
CTD
PMID:19647056
NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
G
Tnfrsf4
TNF receptor superfamily member 4
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TNFRSF4 mRNA
CTD
PMID:21404309
NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599
G
Tnfsf13
TNF superfamily member 13
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of TNFSF13 mRNA
CTD
PMID:21404309
NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042
G
Tnfsf14
TNF superfamily member 14
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TNFSF14 mRNA
CTD
PMID:19647056
NCBI chr 9:2,068,295...2,073,128
Ensembl chr 9:2,069,104...2,073,216
G
Tomm40
translocase of outer mitochondrial membrane 40
affects binding
ISO
Dinitrochlorobenzene binds to TOMM40 protein
CTD
PMID:32991956
NCBI chr 1:79,358,781...79,370,882
Ensembl chr 1:79,358,786...79,370,915
G
Top2b
DNA topoisomerase II beta
affects binding
ISO
Dinitrochlorobenzene binds to TOP2B protein
CTD
PMID:32991956
NCBI chr15:9,051,340...9,111,721
Ensembl chr15:9,051,341...9,112,085
G
Tpp2
tripeptidyl peptidase 2
affects binding
ISO
Dinitrochlorobenzene binds to TPP2 protein
CTD
PMID:32991956
NCBI chr 9:46,046,712...46,128,157
Ensembl chr 9:46,046,632...46,128,157
G
Tpr
translocated promoter region, nuclear basket protein
affects binding
ISO
Dinitrochlorobenzene binds to TPR protein
CTD
PMID:32991956
NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
G
Trem1
triggering receptor expressed on myeloid cells 1
increases expression affects expression
ISO
Dinitrochlorobenzene results in increased expression of TREM1 protein Dinitrochlorobenzene affects the expression of TREM1 mRNA
CTD
PMID:33774146
NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
G
Trex1
three prime repair exonuclease 1
increases expression
EXP
Dinitrochlorobenzene results in increased expression of TREX1 mRNA
CTD
PMID:21893156
NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
G
Trim28
tripartite motif-containing 28
affects binding
ISO
Dinitrochlorobenzene binds to TRIM28 protein
CTD
PMID:32991956
NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
G
Trmt6
tRNA methyltransferase 6 non-catalytic subunit
affects binding
ISO
Dinitrochlorobenzene binds to TRMT6 protein
CTD
PMID:32991956
NCBI chr 3:120,074,899...120,086,639
Ensembl chr 3:120,074,911...120,086,559
G
Trpm4
transient receptor potential cation channel, subfamily M, member 4
affects binding
ISO
Dinitrochlorobenzene binds to TRPM4 protein
CTD
PMID:32991956
NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
G
Trpm6
transient receptor potential cation channel, subfamily M, member 6
affects expression
ISO
Dinitrochlorobenzene affects the expression of TRPM6 mRNA
CTD
PMID:22302311
NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
G
Tslp
thymic stromal lymphopoietin
increases expression multiple interactions
ISO
Dinitrochlorobenzene results in increased expression of TSLP mRNA [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TSLP mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TSLP mRNA]
CTD
PMID:19647056 PMID:23499868
NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
G
Ttc1
tetratricopeptide repeat domain 1
affects binding
ISO
Dinitrochlorobenzene binds to TTC1 protein
CTD
PMID:32991956
NCBI chr10:28,202,325...28,227,464
Ensembl chr10:28,202,325...28,227,472
G
Txn1
thioredoxin 1
multiple interactions increases expression increases oxidation
ISO
Dinitrochlorobenzene inhibits the reaction [Selegiline results in increased expression of TXN]; Dinitrochlorobenzene inhibits the reaction [TXN protein affects the susceptibility to Selegiline] Dinitrochlorobenzene results in increased expression of TXN1 mRNA Dinitrochlorobenzene results in increased oxidation of TXN protein
CTD
PMID:16099847 PMID:19647056 PMID:26975474
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
G
Txn2
thioredoxin 2
increases expression increases oxidation
ISO
Dinitrochlorobenzene results in increased expression of TXN2 mRNA Dinitrochlorobenzene results in increased oxidation of TXN2 protein
CTD
PMID:20566472 PMID:26975474
NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
G
Txnrd1
thioredoxin reductase 1
multiple interactions increases expression increases oxidation
ISO EXP
Dinitrochlorobenzene inhibits the reaction [TXNRD1 protein affects the metabolism of Dithionitrobenzoic Acid] Dinitrochlorobenzene results in increased expression of TXNRD1 mRNA Dinitrochlorobenzene results in increased oxidation of TXNRD1 protein [Dinitrochlorobenzene binds to TXNRD1 protein] inhibits the reaction [TXNRD1 protein results in increased reduction of Dithionitrobenzoic Acid]; Dinitrochlorobenzene promotes the reaction [[TXNRD1 protein co-treated with NADP] results in increased abundance of Superoxides]
CTD
PMID:17229725 PMID:17374397 PMID:20146380 PMID:20457604 PMID:20566472 PMID:21782934 More...
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
G
Txnrd2
thioredoxin reductase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TXNRD2 mRNA
CTD
PMID:20566472
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
G
Tyms
thymidylate synthetase
increases expression
ISO
Dinitrochlorobenzene results in increased expression of TYMS mRNA
CTD
PMID:21404309
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
G
Tyrobp
transmembrane immune signaling adaptor Tyrobp
decreases methylation
ISO
Dinitrochlorobenzene results in decreased methylation of TYROBP gene
CTD
PMID:26732893
NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
G
Ubac2
UBA domain containing 2
affects binding
ISO
Dinitrochlorobenzene binds to UBAC2 protein
CTD
PMID:32991956
NCBI chr15:98,960,139...99,107,795
Ensembl chr15:98,960,139...99,107,787
G
Ubd
ubiquitin D
increases expression
EXP
Dinitrochlorobenzene results in increased expression of UBD mRNA
CTD
PMID:21893156
NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639 Ensembl chr20:1,385,864...1,408,639
G
Ube2i
ubiquitin-conjugating enzyme E2I
affects binding
ISO
Dinitrochlorobenzene binds to UBE2I protein
CTD
PMID:32991956
NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443 Ensembl chr10:69,701,618...69,702,443
G
Ubqln1
ubiquilin 1
affects binding
ISO
Dinitrochlorobenzene binds to UBQLN1 protein
CTD
PMID:32991956
NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090
G
Uchl5
ubiquitin C-terminal hydrolase L5
affects binding
ISO
Dinitrochlorobenzene binds to UCHL5 protein
CTD
PMID:32991956
NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502
G
Uck2
uridine-cytidine kinase 2
increases expression
ISO
Dinitrochlorobenzene results in increased expression of UCK2 mRNA
CTD
PMID:21404309
NCBI chr13:79,380,807...79,438,121
Ensembl chr13:79,383,846...79,438,352
G
Ugt1a6
UDP glucuronosyltransferase family 1 member A6
increases expression
ISO
Dinitrochlorobenzene results in increased expression of UGT1A6 mRNA
CTD
PMID:20566472
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Umps
uridine monophosphate synthetase
affects binding
ISO
Dinitrochlorobenzene binds to UMPS protein
CTD
PMID:32991956
NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903
G
Upb1
beta-ureidopropionase 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of UPB1 mRNA
CTD
PMID:21404309
NCBI chr20:13,217,252...13,243,590
Ensembl chr20:13,217,258...13,243,590
G
Urb1
URB1 ribosome biogenesis homolog
affects binding
ISO
Dinitrochlorobenzene binds to URB1 protein
CTD
PMID:32991956
NCBI chr11:30,004,539...30,065,315
Ensembl chr11:30,004,539...30,065,363
G
Usp18
ubiquitin specific peptidase 18
increases expression
ISO
Dinitrochlorobenzene results in increased expression of USP18 mRNA
CTD
PMID:19647056
NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144
G
Utp20
UTP20 small subunit processome component
affects binding
ISO
Dinitrochlorobenzene binds to UTP20 protein
CTD
PMID:32991956
NCBI chr 7:23,134,630...23,215,639
Ensembl chr 7:23,134,637...23,215,632
G
Utp25
UTP25 small subunit processome component
affects binding
ISO
Dinitrochlorobenzene binds to DIEXF protein
CTD
PMID:32991956
NCBI chr13:104,630,390...104,651,681
Ensembl chr13:104,630,391...104,651,662
G
Vcl
vinculin
affects binding
ISO
Dinitrochlorobenzene binds to VCL protein
CTD
PMID:32991956
NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
G
Vcp
valosin-containing protein
affects binding
ISO
Dinitrochlorobenzene binds to VCP protein
CTD
PMID:32991956
NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
G
Vdr
vitamin D receptor
increases expression
ISO
Dinitrochlorobenzene results in increased expression of VDR mRNA
CTD
PMID:17374397
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
G
Vegfa
vascular endothelial growth factor A
increases expression
ISO
Dinitrochlorobenzene results in increased expression of VEGFA protein
CTD
PMID:25617811
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
G
Vegfc
vascular endothelial growth factor C
increases expression
ISO
Dinitrochlorobenzene results in increased expression of VEGFC mRNA
CTD
PMID:25617811
NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
G
Vegfd
vascular endothelial growth factor D
increases expression
ISO
Dinitrochlorobenzene results in increased expression of VEGFD mRNA
CTD
PMID:20146380
NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
G
Vps29
VPS29 retromer complex component
affects binding
ISO
Dinitrochlorobenzene binds to VPS29 protein
CTD
PMID:32991956
NCBI chr12:34,208,911...34,217,977
Ensembl chr12:34,207,263...34,217,964
G
Vsnl1
visinin-like 1
affects binding
ISO
Dinitrochlorobenzene binds to VSNL1 protein
CTD
PMID:32991956
NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479
G
Wdr36
WD repeat domain 36
affects binding
ISO
Dinitrochlorobenzene binds to WDR36 protein
CTD
PMID:32991956
NCBI chr18:24,473,657...24,501,773
Ensembl chr18:24,473,663...24,508,092
G
Zbp1
Z-DNA binding protein 1
increases expression
ISO
Dinitrochlorobenzene results in increased expression of ZBP1 mRNA
CTD
PMID:18242016 PMID:19647056
NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870
G
Zbtb17
zinc finger and BTB domain containing 17
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ZBTB17 mRNA
CTD
PMID:17374397
NCBI chr 5:153,753,508...153,774,613
Ensembl chr 5:153,753,569...153,774,609
G
Zfp326
zinc finger protein 326
affects binding
ISO
Dinitrochlorobenzene binds to ZNF326 protein
CTD
PMID:32991956
NCBI chr14:3,941,210...3,980,419
Ensembl chr14:3,941,958...3,980,384
G
Zfp36l1
zinc finger protein 36, C3H type-like 1
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ZFP36L1 mRNA
CTD
PMID:17374397
NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
G
Zfp469
zinc finger protein 469
affects binding
ISO
Dinitrochlorobenzene binds to ZNF469 protein
CTD
PMID:32991956
NCBI chr19:50,282,337...50,324,010
G
Zfyve26
zinc finger FYVE-type containing 26
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ZFYVE26 mRNA
CTD
PMID:17374397
NCBI chr 6:98,031,874...98,095,538
Ensembl chr 6:98,032,520...98,095,480
G
Zmym3
zinc finger MYM-type containing 3
decreases expression
ISO
Dinitrochlorobenzene results in decreased expression of ZMYM3 mRNA
CTD
PMID:17374397
NCBI chr X:66,528,585...66,544,234
Ensembl chr X:66,528,585...66,544,782
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all