CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: dieldrin
Accession: CHEBI:34696
browse the term
Definition: An organochlorine compound resulting from the epoxidation of the double bond of aldrin. It is the active metabolite of the proinsecticde aldrin.
Synonyms: exact_synonym: rel-(1R,2S,3S,6R,7R,8S,9S,11R)-3,4,5,6,13,13-hexachloro-10-oxapentacyclo[6.3.1.1(3,6).0(2,7).0(9,11)]tridec-4-ene
related_synonym: (1R,4S,4aS,5R,6R,7S,8S,8aR)-1,2,3,4,10,10-Hexachloro-1,4,4a,5,6,7,8,8a-octahydro-6,7-epoxy-1,4:5,8-dimethanonaphthalene; (1aalpha,2beta,2aalpha,3beta,6beta,6aalpha,7beta,7aalpha)-3,4,5,6,9,9-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphtho[2,3-b]oxirene; 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4-endo-exo-5,8-dimethanonaphthalene; 2,7:3,6-Dimethanonaphth[2,3-b]oxirene, 3,4,5,6,9,9-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-, (1aalpha,2beta,2aalpha,3beta,6beta,6aalpha,7beta,7aalpha)-; Formula=C12H8Cl6O; HEOD; InChI=1S/C12H8Cl6O/c13-8-9(14)11(16)5-3-1-2(6-7(3)19-6)4(5)10(8,15)12(11,17)18/h2-7H,1H2/t2-,3+,4+,5-,6-,7+,10+,11-; InChIKey=DFBKLUNHFCTMDC-PICURKEMSA-N; SMILES=[H][C@]12[C@H]3C[C@H]([C@@H]4O[C@H]34)[C@@]1([H])[C@@]1(Cl)C(Cl)=C(Cl)[C@]2(Cl)C1(Cl)Cl
xref: CAS:60-57-1; KEGG:C13718
xref_mesh: MESH:D004026
xref: PMID:17848404; PMID:17999924; PMID:18497062; PMID:20602524; PMID:21724225; PMID:22281775; PMID:23001942; PMID:23726008; PMID:23763672; PMID:8597127; PPDB:226; Pesticides:dieldrin; Reaxys:91396; Wikipedia:Dieldrin
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Aadac
arylacetamide deacetylase
decreases expression
ISO
Dieldrin results in decreased expression of AADAC mRNA
CTD
PMID:23153324
NCBI chr 3:59,939,209...59,947,578
Ensembl chr 3:59,933,138...59,947,581
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Abcb1a
ATP-binding cassette, sub-family B member 1A
increases expression
ISO
Dieldrin results in increased expression of ABCB1 mRNA
CTD
PMID:24464585
NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
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Abcc1
ATP-binding cassette, sub-family C member 1
increases expression
ISO
Dieldrin results in increased expression of ABCC1 mRNA
CTD
PMID:23153324
NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
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Abcc2
ATP-binding cassette, sub-family member 2
increases expression
ISO
Dieldrin results in increased expression of ABCC2 mRNA
CTD
PMID:24464585
NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
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Abcg2
ATP binding cassette subfamily G member 2 (Junior blood group)
increases expression
ISO
Dieldrin results in increased expression of ABCG2 mRNA
CTD
PMID:24464585
NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
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Acly
ATP citrate lyase
affects expression
ISO
Dieldrin affects the expression of ACLY mRNA
CTD
PMID:22546817
NCBI chr11:100,367,178...100,418,826
Ensembl chr11:100,367,179...100,418,826
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Acsm3
acyl-CoA synthetase medium-chain family member 3
decreases expression
ISO
Dieldrin results in decreased expression of ACSM3 mRNA
CTD
PMID:23153324
NCBI chr 7:119,360,106...119,384,119
Ensembl chr 7:119,360,146...119,386,736
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Actn1
actinin, alpha 1
affects expression
ISO
Dieldrin affects the expression of ACTN1 mRNA
CTD
PMID:22546817
NCBI chr12:80,214,316...80,307,165
Ensembl chr12:80,214,321...80,307,145
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Acvr1c
activin A receptor, type IC
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVR1C mRNA
CTD
PMID:19422813
NCBI chr 2:58,157,465...58,247,909
Ensembl chr 2:58,157,465...58,247,907
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Acvrl1
activin A receptor, type II-like 1
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVRL1 mRNA
CTD
PMID:19422813
NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217
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Adam15
ADAM metallopeptidase domain 15
decreases expression
ISO
Dieldrin results in decreased expression of ADAM15 mRNA
CTD
PMID:31068361
NCBI chr 3:89,246,947...89,257,589
Ensembl chr 3:89,245,849...89,257,303
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Adam17
a disintegrin and metallopeptidase domain 17
affects expression
ISO
Dieldrin affects the expression of ADAM17 mRNA
CTD
PMID:22546817
NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
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Adra2b
adrenergic receptor, alpha 2b
decreases expression
ISO
Dieldrin results in decreased expression of ADRA2B mRNA
CTD
PMID:18812211
NCBI chr 2:127,205,099...127,209,141
Ensembl chr 2:127,205,128...127,209,141
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Adrb1
adrenergic receptor, beta 1
affects expression
ISO
Dieldrin affects the expression of ADRB1 mRNA
CTD
PMID:18812211
NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545
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Adrb2
adrenergic receptor, beta 2
affects expression
ISO
Dieldrin affects the expression of ADRB2 mRNA
CTD
PMID:18812211
NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
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Ahr
aryl-hydrocarbon receptor
increases activity
ISO
Dieldrin results in increased activity of AHR protein
CTD
PMID:14636698
NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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Aifm2
apoptosis-inducing factor, mitochondrion-associated 2
affects expression
ISO
Dieldrin affects the expression of AIFM2 mRNA
CTD
PMID:22546817
NCBI chr10:61,551,042...61,575,474
Ensembl chr10:61,551,042...61,575,039
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Akt2
thymoma viral proto-oncogene 2
affects expression
ISO
Dieldrin affects the expression of AKT2 mRNA
CTD
PMID:22546817
NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
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Alk
anaplastic lymphoma kinase
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ALK mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of ALK mRNA
CTD
PMID:19422813 PMID:28263720
NCBI chr17:72,174,206...72,911,719
Ensembl chr17:72,175,967...72,911,622
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Alox15
arachidonate 15-lipoxygenase
affects expression
ISO
Dieldrin affects the expression of ALOX15 mRNA
CTD
PMID:22546817
NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857
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Amigo2
adhesion molecule with Ig like domain 2
affects expression
ISO
Dieldrin affects the expression of AMIGO2 mRNA
CTD
PMID:22546817
NCBI chr15:97,141,955...97,145,168
Ensembl chr15:97,142,006...97,145,168
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Anxa1
annexin A1
affects expression
ISO
Dieldrin affects the expression of ANXA1 mRNA
CTD
PMID:22546817
NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
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Aox1
aldehyde oxidase 1
multiple interactions increases expression
EXP
NR1I3 protein affects the reaction [Dieldrin results in increased expression of AOX1 mRNA]
CTD
PMID:32435917
NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572
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Apaf1
apoptotic peptidase activating factor 1
affects expression
ISO
Dieldrin affects the expression of APAF1 mRNA
CTD
PMID:22546817
NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
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Apbb1
amyloid beta precursor protein binding family B member 1
affects expression
ISO
Dieldrin affects the expression of APBB1 mRNA
CTD
PMID:22546817
NCBI chr 7:105,207,691...105,231,151
Ensembl chr 7:105,207,690...105,230,860
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Apbb2
amyloid beta precursor protein binding family B member 2
affects expression
ISO
Dieldrin affects the expression of APBB2 mRNA
CTD
PMID:22546817
NCBI chr 5:66,456,068...66,779,189
Ensembl chr 5:66,456,046...66,776,127
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Apbb3
amyloid beta precursor protein binding family B member 3
affects expression
ISO
Dieldrin affects the expression of APBB3 mRNA
CTD
PMID:22546817
NCBI chr18:36,804,207...36,812,419
Ensembl chr18:36,804,207...36,812,419
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Apex2
apurinic/apyrimidinic endonuclease 2
affects expression
ISO
Dieldrin affects the expression of APEX2 mRNA
CTD
PMID:22546817
NCBI chr X:149,286,625...149,371,175
Ensembl chr X:149,302,515...149,372,864
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Api5
apoptosis inhibitor 5
affects expression
ISO
Dieldrin affects the expression of API5 mRNA
CTD
PMID:22546817
NCBI chr 2:94,242,073...94,268,490
Ensembl chr 2:94,242,027...94,268,481
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Aplp1
amyloid beta precursor like protein 1
affects expression
ISO
Dieldrin affects the expression of APLP1 mRNA
CTD
PMID:22546817
NCBI chr 7:30,134,405...30,144,960
Ensembl chr 7:30,134,407...30,144,960
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App
amyloid beta precursor protein
affects expression
ISO
Dieldrin affects the expression of APP mRNA
CTD
PMID:22546817
NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
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Aqp11
aquaporin 11
decreases expression
ISO
Dieldrin results in decreased expression of AQP11 mRNA
CTD
PMID:23153324
NCBI chr 7:97,375,586...97,387,454
Ensembl chr 7:97,373,213...97,387,496
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Aqp9
aquaporin 9
decreases expression
ISO
Dieldrin results in decreased expression of AQP9 mRNA
CTD
PMID:23153324
NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964
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Ar
androgen receptor
multiple interactions
ISO
Dieldrin inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Dieldrin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Dieldrin inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [Dieldrin results in increased activity of AR protein]
CTD
PMID:15064155 PMID:18324785 PMID:21295777 PMID:26022396
NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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Araf
Araf proto-oncogene, serine/threonine kinase
affects expression
ISO
Dieldrin affects the expression of ARAF mRNA
CTD
PMID:22546817
NCBI chr X:20,663,946...20,726,760
Ensembl chr X:20,664,053...20,726,758
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Arc
activity regulated cytoskeletal-associated protein
increases expression
ISO
Dieldrin results in increased expression of ARC mRNA
CTD
PMID:31068361
NCBI chr15:74,540,930...74,544,419
Ensembl chr15:74,540,932...74,544,419
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Arhgef6
Rac/Cdc42 guanine nucleotide exchange factor 6
affects expression
ISO
Dieldrin affects the expression of ARHGEF6 mRNA
CTD
PMID:22546817
NCBI chr X:56,276,845...56,384,119
Ensembl chr X:56,276,845...56,384,089
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Arih2
ariadne RBR E3 ubiquitin protein ligase 2
decreases response to substance
ISO
ARIH2 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 9:108,480,141...108,531,917
Ensembl chr 9:108,480,141...108,526,585
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Atf3
activating transcription factor 3
increases expression
ISO
Dieldrin results in increased expression of ATF3 mRNA
CTD
PMID:31068361
NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
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Atg10
autophagy related 10
increases response to substance
ISO
ATG10 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr13:91,083,467...91,372,189
Ensembl chr13:91,083,475...91,372,087
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Atg101
autophagy related 101
increases response to substance
ISO
ATG101 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr15:101,182,182...101,188,855
Ensembl chr15:101,182,153...101,188,826
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Atg4b
autophagy related 4B, cysteine peptidase
increases response to substance
ISO
ATG4B gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 1:93,682,627...93,717,328
Ensembl chr 1:93,679,222...93,718,332
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Atg9a
autophagy related 9A
increases response to substance
ISO
ATG9A gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 1:75,157,509...75,168,654
Ensembl chr 1:75,157,504...75,168,840
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Atm
ataxia telangiectasia mutated
affects expression
ISO
Dieldrin affects the expression of ATM mRNA
CTD
PMID:22546817
NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
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Atp13a2
ATPase type 13A2
decreases expression
ISO
Dieldrin results in decreased expression of ATP13A2 mRNA
CTD
PMID:31068361
NCBI chr 4:140,711,812...140,734,641
Ensembl chr 4:140,714,184...140,734,641
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Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
decreases expression
ISO
Dieldrin results in decreased expression of ATP2A2 mRNA
CTD
PMID:23153324
NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
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Aurka
aurora kinase A
affects expression increases expression
ISO
Dieldrin affects the expression of AURKA mRNA Dieldrin results in increased expression of AURKA mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr 2:172,198,116...172,212,825
Ensembl chr 2:172,198,110...172,212,455
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Aurkb
aurora kinase B
affects expression
ISO
Dieldrin affects the expression of AURKB mRNA
CTD
PMID:22546817
NCBI chr11:68,936,477...68,942,490
Ensembl chr11:68,936,473...68,942,490
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Aven
apoptosis, caspase activation inhibitor
affects expression
ISO
Dieldrin affects the expression of AVEN mRNA
CTD
PMID:22546817
NCBI chr 2:112,323,231...112,461,598
Ensembl chr 2:112,323,309...112,464,918
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Avpr1b
arginine vasopressin receptor 1B
increases expression
ISO
Dieldrin results in increased expression of AVPR1B mRNA
CTD
PMID:20682304
NCBI chr 1:131,526,908...131,539,740
Ensembl chr 1:131,526,977...131,539,738
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Babam2
BRISC and BRCA1 A complex member 2
affects expression
ISO
Dieldrin affects the expression of BABAM2 mRNA
CTD
PMID:22546817
NCBI chr 5:31,855,394...32,242,083
Ensembl chr 5:31,855,028...32,242,306
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Bag1
BCL2-associated athanogene 1
affects expression
ISO
Dieldrin affects the expression of BAG1 mRNA
CTD
PMID:22546817
NCBI chr 4:40,936,398...40,948,294
Ensembl chr 4:40,936,398...40,948,294
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Bag3
BCL2-associated athanogene 3
affects expression
ISO
Dieldrin affects the expression of BAG3 mRNA
CTD
PMID:22546817
NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705
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Bak1
BCL2-antagonist/killer 1
affects expression
ISO
Dieldrin affects the expression of BAK1 mRNA
CTD
PMID:22546817
NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
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Bax
BCL2-associated X protein
affects expression
ISO
Dieldrin affects the expression of BAX mRNA
CTD
PMID:22546817
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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Bbc3
BCL2 binding component 3
affects expression
ISO
Dieldrin affects the expression of BBC3 mRNA
CTD
PMID:22546817
NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130
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Bcat1
branched chain aminotransferase 1, cytosolic
increases expression
ISO
Dieldrin results in increased expression of BCAT1 mRNA
CTD
PMID:23153324
NCBI chr 6:144,939,561...145,021,883
Ensembl chr 6:144,939,561...145,021,910
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Bcl2
B cell leukemia/lymphoma 2
decreases response to substance multiple interactions
ISO
BCL2 protein results in decreased susceptibility to Dieldrin BCL2 protein inhibits the reaction [Dieldrin results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Dieldrin results in increased activity of PRKCD protein]
CTD
PMID:15033812 PMID:15183012
NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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Bcl2l1
BCL2-like 1
affects expression
ISO
Dieldrin affects the expression of BCL2L1 mRNA
CTD
PMID:22546817
NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
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Bcl2l10
Bcl2-like 10
affects expression
ISO
Dieldrin affects the expression of BCL2L10 mRNA
CTD
PMID:22546817
NCBI chr 9:75,255,040...75,258,922
Ensembl chr 9:75,255,040...75,258,931
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Bcl2l11
BCL2 like 11
affects expression
ISO
Dieldrin affects the expression of BCL2L11 mRNA
CTD
PMID:22546817
NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
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Bcl2l13
BCL2 like 13
affects expression
ISO
Dieldrin affects the expression of BCL2L13 mRNA
CTD
PMID:22546817
NCBI chr 6:120,813,167...120,869,803
Ensembl chr 6:120,813,173...120,869,803
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Bcl2l14
BCL2 like 14
affects expression
ISO
Dieldrin affects the expression of BCL2L14 mRNA
CTD
PMID:22546817
NCBI chr 6:134,373,292...134,415,687
Ensembl chr 6:134,373,281...134,415,699
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Bcl3
B cell leukemia/lymphoma 3
affects expression
ISO
Dieldrin affects the expression of BCL3 mRNA
CTD
PMID:22546817
NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
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Bcl6
B cell leukemia/lymphoma 6
affects expression
ISO
Dieldrin affects the expression of BCL6 mRNA
CTD
PMID:22546817
NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602
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Bex3
brain expressed X-linked 3
increases expression affects expression
ISO
Dieldrin results in increased expression of BEX3 mRNA Dieldrin affects the expression of BEX3 mRNA
CTD
PMID:19130878 PMID:22546817
NCBI chr X:135,171,002...135,172,727
Ensembl chr X:135,171,002...135,172,727
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Bfar
bifunctional apoptosis regulator
affects expression
ISO
Dieldrin affects the expression of BFAR mRNA
CTD
PMID:22546817
NCBI chr16:13,489,722...13,521,476
Ensembl chr16:13,489,722...13,521,476 Ensembl chr16:13,489,722...13,521,476
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Bhlha15
basic helix-loop-helix family, member a15
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of BHLHA15 mRNA
CTD
PMID:28263720
NCBI chr 5:144,127,104...144,131,259
Ensembl chr 5:144,127,104...144,131,259
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Bid
BH3 interacting domain death agonist
affects expression
ISO
Dieldrin affects the expression of BID mRNA
CTD
PMID:22546817
NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
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Bik
BCL2-interacting killer
affects expression
ISO
Dieldrin affects the expression of BIK mRNA
CTD
PMID:22546817
NCBI chr15:83,410,992...83,428,836
Ensembl chr15:83,411,063...83,428,835
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Bin1
bridging integrator 1
affects expression
ISO
Dieldrin affects the expression of BIN1 mRNA
CTD
PMID:22546817
NCBI chr18:32,509,671...32,568,793
Ensembl chr18:32,510,283...32,568,790
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Bin3
bridging integrator 3
affects expression
ISO
Dieldrin affects the expression of BIN3 mRNA
CTD
PMID:22546817
NCBI chr14:70,337,538...70,375,413
Ensembl chr14:70,337,554...70,375,655
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Birc3
baculoviral IAP repeat-containing 3
affects expression
ISO
Dieldrin affects the expression of BIRC3 mRNA
CTD
PMID:22546817
NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187
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Birc5
baculoviral IAP repeat-containing 5
affects expression
ISO
Dieldrin affects the expression of BIRC5 mRNA
CTD
PMID:22546817
NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
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Birc6
baculoviral IAP repeat-containing 6
increases response to substance
ISO
BIRC6 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr17:74,835,247...75,010,351
Ensembl chr17:74,835,290...75,010,351
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Bnip3
BCL2/adenovirus E1B interacting protein 3
affects expression
ISO
Dieldrin affects the expression of BNIP3 mRNA
CTD
PMID:22546817
NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
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Bnip3l
BCL2/adenovirus E1B interacting protein 3-like
affects expression
ISO
Dieldrin affects the expression of BNIP3L mRNA
CTD
PMID:22546817
NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326
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Brca1
breast cancer 1, early onset
affects expression
ISO
Dieldrin affects the expression of BRCA1 mRNA
CTD
PMID:22546817
NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
G
Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
affects expression
ISO
Dieldrin affects the expression of BRINP1 mRNA
CTD
PMID:22546817
NCBI chr 4:68,679,609...68,872,634
Ensembl chr 4:68,679,751...68,872,634
G
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
affects expression
ISO
Dieldrin affects the expression of BRINP2 mRNA
CTD
PMID:22546817
NCBI chr 1:158,072,835...158,185,096
Ensembl chr 1:158,072,839...158,183,896
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Btg1
BTG anti-proliferation factor 1
affects expression
ISO
Dieldrin affects the expression of BTG1 mRNA
CTD
PMID:22546817
NCBI chr10:96,452,863...96,458,675
Ensembl chr10:96,452,868...96,458,671
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Btg2
BTG anti-proliferation factor 2
increases expression
ISO
Dieldrin results in increased expression of BTG2 mRNA
CTD
PMID:31068361
NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
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Btg3
BTG anti-proliferation factor 3
affects expression
ISO
Dieldrin affects the expression of BTG3 mRNA
CTD
PMID:22546817
NCBI chr16:78,156,748...78,174,069
Ensembl chr16:78,129,525...78,174,080
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Bzw1
basic leucine zipper and W2 domains 1
affects expression
ISO
Dieldrin affects the expression of BZW1 mRNA
CTD
PMID:22546817
NCBI chr 1:58,432,057...58,446,513
Ensembl chr 1:58,432,057...58,446,512
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Cables1
CDK5 and Abl enzyme substrate 1
affects expression
ISO
Dieldrin affects the expression of CABLES1 mRNA
CTD
PMID:22546817
NCBI chr18:11,972,600...12,078,681
Ensembl chr18:11,972,277...12,078,687
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Calm2
calmodulin 2
affects expression
ISO
Dieldrin affects the expression of CALM2 mRNA
CTD
PMID:22546817
NCBI chr17:87,740,829...87,754,363
Ensembl chr17:87,740,840...87,754,363
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Camk2a
calcium/calmodulin-dependent protein kinase II alpha
affects expression
ISO
Dieldrin affects the expression of CAMK2A mRNA
CTD
PMID:22546817
NCBI chr18:61,058,704...61,121,224
Ensembl chr18:61,058,690...61,121,224
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Camk2b
calcium/calmodulin-dependent protein kinase II, beta
affects expression
ISO
Dieldrin affects the expression of CAMK2B mRNA
CTD
PMID:22546817
NCBI chr11:5,919,642...6,016,401
Ensembl chr11:5,919,644...6,016,362
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Camk2g
calcium/calmodulin-dependent protein kinase II gamma
affects expression
ISO
Dieldrin affects the expression of CAMK2G mRNA
CTD
PMID:22546817
NCBI chr14:20,784,943...20,844,225
Ensembl chr14:20,784,943...20,844,156
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Cand1
cullin associated and neddylation disassociated 1
affects expression
ISO
Dieldrin affects the expression of CAND1 mRNA
CTD
PMID:22546817
NCBI chr10:119,034,717...119,075,960
Ensembl chr10:119,035,160...119,075,960
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Card9
caspase recruitment domain family, member 9
affects expression
ISO
Dieldrin affects the expression of CARD9 mRNA
CTD
PMID:22546817
NCBI chr 2:26,242,199...26,250,957
Ensembl chr 2:26,242,188...26,250,930
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Casp12
caspase 12
affects expression
ISO
Dieldrin affects the expression of CASP12 mRNA
CTD
PMID:22546817
NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032
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Casp3
caspase 3
decreases activity multiple interactions increases activity
ISO EXP
Dieldrin results in decreased activity of CASP3 protein [Hexachlorocyclohexane co-treated with Dieldrin] results in increased activity of CASP3 protein; Dieldrin inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein]; Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]; FYN protein promotes the reaction [Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]]; rottlerin inhibits the reaction [Dieldrin results in increased activity of CASP3 protein]; SNCA protein promotes the reaction [Dieldrin results in increased expression of CASP3 protein] BCL2 protein inhibits the reaction [Dieldrin results in increased activity of CASP3 protein]
CTD
PMID:10200566 PMID:12831855 PMID:15033812 PMID:15183012 PMID:15987830 PMID:20036686 PMID:21801747 PMID:22634143 More...
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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Casp4
caspase 4, apoptosis-related cysteine peptidase
affects expression
ISO
Dieldrin affects the expression of CASP4 mRNA
CTD
PMID:22546817
NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
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Casp7
caspase 7
multiple interactions affects expression
ISO
[Hexachlorocyclohexane co-treated with Dieldrin] results in increased activity of CASP7 protein Dieldrin affects the expression of CASP7 mRNA
CTD
PMID:20036686 PMID:22546817
NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
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Casp8
caspase 8
affects expression
ISO
Dieldrin affects the expression of CASP8 mRNA
CTD
PMID:22546817
NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
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Casp8ap2
caspase 8 associated protein 2
affects expression
ISO
Dieldrin affects the expression of CASP8AP2 mRNA
CTD
PMID:22546817
NCBI chr 4:32,615,462...32,653,271
Ensembl chr 4:32,615,451...32,653,265
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Casp9
caspase 9
increases activity
ISO
Dieldrin results in increased activity of CASP9 protein
CTD
PMID:12831855
NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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Cbl
Casitas B-lineage lymphoma
decreases response to substance
ISO
CBL gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346
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Cbx6
chromobox 6
decreases expression
ISO
Dieldrin results in decreased expression of CBX6 mRNA
CTD
PMID:31068361
NCBI chr15:79,708,099...79,718,534
Ensembl chr15:79,708,097...79,718,889
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Cckbr
cholecystokinin B receptor
increases expression
ISO
Dieldrin results in increased expression of CCKBR mRNA
CTD
PMID:20682304
NCBI chr 7:105,075,201...105,085,546
Ensembl chr 7:105,074,938...105,120,105
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Ccnb1
cyclin B1
affects expression increases expression
ISO
Dieldrin affects the expression of CCNB1 mRNA Dieldrin results in increased expression of CCNB1 mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
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Ccnb2
cyclin B2
increases expression
ISO
Dieldrin results in increased expression of CCNB2 mRNA
CTD
PMID:23153324
NCBI chr 9:70,314,971...70,328,836
Ensembl chr 9:70,314,974...70,328,829
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Ccnd1
cyclin D1
affects expression
ISO
Dieldrin affects the expression of CCND1 mRNA
CTD
PMID:22546817
NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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Ccne1
cyclin E1
affects expression
ISO
Dieldrin affects the expression of CCNE1 mRNA
CTD
PMID:22546817
NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
G
Ccne2
cyclin E2
affects expression
ISO
Dieldrin affects the expression of CCNE2 mRNA
CTD
PMID:22546817
NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779
G
Ccnf
cyclin F
affects expression
ISO
Dieldrin affects the expression of CCNF mRNA
CTD
PMID:22546817
NCBI chr17:24,441,518...24,470,333
Ensembl chr17:24,441,172...24,470,458
G
Ccnh
cyclin H
affects expression
ISO
Dieldrin affects the expression of CCNH mRNA
CTD
PMID:22546817
NCBI chr13:85,337,504...85,361,850
Ensembl chr13:85,337,527...85,371,588
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Ccnj
cyclin J
affects expression
ISO
Dieldrin affects the expression of CCNJ mRNA
CTD
PMID:22546817
NCBI chr19:40,819,345...40,837,016
Ensembl chr19:40,819,723...40,837,016
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Ccnt2
cyclin T2
affects expression
ISO
Dieldrin affects the expression of CCNT2 mRNA
CTD
PMID:22546817
NCBI chr 1:127,701,901...127,732,574
Ensembl chr 1:127,701,901...127,735,798
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Ccpg1
cell cycle progression 1
affects expression
ISO
Dieldrin affects the expression of CCPG1 mRNA
CTD
PMID:22546817
NCBI chr 9:72,892,692...72,923,622
Ensembl chr 9:72,892,711...72,923,622
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Cd3g
CD3 antigen, gamma polypeptide
affects expression
ISO
Dieldrin affects the expression of CD3G mRNA
CTD
PMID:22546817
NCBI chr 9:44,880,870...44,891,729
Ensembl chr 9:44,880,870...44,891,729
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Cd69
CD69 antigen
increases expression
ISO
Dieldrin results in increased expression of CD69 mRNA
CTD
PMID:31068361
NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399
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Cdc20
cell division cycle 20
affects expression
ISO
Dieldrin affects the expression of CDC20 mRNA
CTD
PMID:22546817
NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549
G
Cdc23
CDC23 cell division cycle 23
affects expression
ISO
Dieldrin affects the expression of CDC23 mRNA
CTD
PMID:22546817
NCBI chr18:34,761,401...34,784,802
Ensembl chr18:34,764,004...34,784,788
G
Cdc25b
cell division cycle 25B
affects expression
ISO
Dieldrin affects the expression of CDC25B mRNA
CTD
PMID:22546817
NCBI chr 2:131,028,356...131,040,431
Ensembl chr 2:131,028,869...131,040,417
G
Cdc25c
cell division cycle 25C
affects expression
ISO
Dieldrin affects the expression of CDC25C mRNA
CTD
PMID:22546817
NCBI chr18:34,866,046...34,884,644
Ensembl chr18:34,866,046...34,884,586
G
Cdc26
cell division cycle 26
affects expression
ISO
Dieldrin affects the expression of CDC26 mRNA
CTD
PMID:22546817
NCBI chr 4:62,310,581...62,326,862
Ensembl chr 4:62,301,891...62,326,879
G
Cdc34
cell division cycle 34
affects expression
ISO
Dieldrin affects the expression of CDC34 mRNA
CTD
PMID:22546817
NCBI chr10:79,518,029...79,524,232
Ensembl chr10:79,518,029...79,524,232
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Cdc37l1
cell division cycle 37-like 1
affects expression
ISO
Dieldrin affects the expression of CDC37L1 mRNA
CTD
PMID:22546817
NCBI chr19:28,959,049...29,008,832
Ensembl chr19:28,967,752...29,004,081
G
Cdc6
cell division cycle 6
affects expression
ISO
Dieldrin affects the expression of CDC6 mRNA
CTD
PMID:22546817
NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
G
Cdc7
cell division cycle 7
affects expression
ISO
Dieldrin affects the expression of CDC7 mRNA
CTD
PMID:22546817
NCBI chr 5:107,112,201...107,132,298
Ensembl chr 5:107,112,188...107,132,298
G
Cdca2
cell division cycle associated 2
affects expression
ISO
Dieldrin affects the expression of CDCA2 mRNA
CTD
PMID:22546817
NCBI chr14:67,910,629...67,953,290
Ensembl chr14:67,913,780...67,953,290
G
Cdca3
cell division cycle associated 3
affects expression
ISO
Dieldrin affects the expression of CDCA3 mRNA
CTD
PMID:22546817
NCBI chr 6:124,806,533...124,810,664
Ensembl chr 6:124,806,510...124,810,664
G
Cdca4
cell division cycle associated 4
affects expression
ISO
Dieldrin affects the expression of CDCA4 mRNA
CTD
PMID:22546817
NCBI chr12:112,783,849...112,793,141
Ensembl chr12:112,783,849...112,793,043
G
Cdca8
cell division cycle associated 8
increases expression
ISO
Dieldrin results in increased expression of CDCA8 mRNA
CTD
PMID:23153324
NCBI chr 4:124,812,258...124,830,710
Ensembl chr 4:124,812,258...124,833,104
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Cdh2
cadherin 2
decreases expression
ISO
Dieldrin results in decreased expression of CDH2 protein
CTD
PMID:15082077
NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
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Cdk1
cyclin dependent kinase 1
affects expression
ISO
Dieldrin affects the expression of CDK1 mRNA
CTD
PMID:22546817
NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
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Cdk11b
cyclin dependent kinase 11B
affects expression
ISO
Dieldrin affects the expression of CDK11B mRNA
CTD
PMID:22546817
NCBI chr 4:155,709,303...155,734,392
Ensembl chr 4:155,709,311...155,734,395
G
Cdk13
cyclin dependent kinase 13
affects expression
ISO
Dieldrin affects the expression of CDK13 mRNA
CTD
PMID:22546817
NCBI chr13:17,885,309...17,979,960
Ensembl chr13:17,884,900...17,979,682
G
Cdk2
cyclin dependent kinase 2
affects expression
ISO
Dieldrin affects the expression of CDK2 mRNA
CTD
PMID:22546817
NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
G
Cdk6
cyclin dependent kinase 6
affects expression
ISO
Dieldrin affects the expression of CDK6 mRNA
CTD
PMID:22546817
NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008
G
Cdkn1a
cyclin dependent kinase inhibitor 1A
affects expression
ISO
Dieldrin affects the expression of CDKN1A mRNA
CTD
PMID:22546817
NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
G
Cdkn1c
cyclin dependent kinase inhibitor 1C
affects expression
ISO
Dieldrin affects the expression of CDKN1C mRNA
CTD
PMID:22546817
NCBI chr 7:143,012,076...143,014,735
Ensembl chr 7:143,012,076...143,014,787
G
Cdkn3
cyclin dependent kinase inhibitor 3
affects expression increases expression
ISO
Dieldrin affects the expression of CDKN3 mRNA Dieldrin results in increased expression of CDKN3 mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr14:46,997,912...47,008,987
Ensembl chr14:46,997,998...47,009,126
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Cebpb
CCAAT/enhancer binding protein beta
affects expression
ISO
Dieldrin affects the expression of CEBPB mRNA
CTD
PMID:22546817
NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
G
Cenpe
centromere protein E
increases expression
ISO
Dieldrin results in increased expression of CENPE mRNA
CTD
PMID:23153324
NCBI chr 3:134,918,324...134,979,301
Ensembl chr 3:134,918,298...134,979,372
G
Cenpf
centromere protein F
affects expression
ISO
Dieldrin affects the expression of CENPF mRNA
CTD
PMID:22546817
NCBI chr 1:189,372,803...189,420,302
Ensembl chr 1:189,372,803...189,420,283
G
Cfdp1
craniofacial development protein 1
affects expression
ISO
Dieldrin affects the expression of CFDP1 mRNA
CTD
PMID:22546817
NCBI chr 8:112,493,314...112,580,969
Ensembl chr 8:112,495,123...112,580,923
G
Cgn
cingulin
decreases expression
ISO
Dieldrin results in decreased expression of CGN mRNA
CTD
PMID:23153324
NCBI chr 3:94,667,376...94,695,036
Ensembl chr 3:94,667,376...94,693,826
G
Cgrrf1
cell growth regulator with ring finger domain 1
affects expression
ISO
Dieldrin affects the expression of CGRRF1 mRNA
CTD
PMID:22546817
NCBI chr14:47,069,591...47,091,655
Ensembl chr14:47,069,582...47,091,650
G
Chek2
checkpoint kinase 2
affects expression
ISO
Dieldrin affects the expression of CHEK2 mRNA
CTD
PMID:22546817
NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
G
Chgb
chromogranin B
decreases expression
ISO
Dieldrin results in decreased expression of CHGB mRNA
CTD
PMID:18812211
NCBI chr 2:132,623,562...132,636,999
Ensembl chr 2:132,623,198...132,636,999
G
Chrm1
cholinergic receptor, muscarinic 1, CNS
decreases expression
ISO
Dieldrin results in decreased expression of CHRM1 mRNA
CTD
PMID:18812211
NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
G
Chrm2
cholinergic receptor, muscarinic 2, cardiac
affects expression
ISO
Dieldrin affects the expression of CHRM2 mRNA
CTD
PMID:18812211
NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
G
Chrm4
cholinergic receptor, muscarinic 4
affects expression
ISO
Dieldrin affects the expression of CHRM4 mRNA
CTD
PMID:18812211
NCBI chr 2:91,752,531...91,760,180
Ensembl chr 2:91,757,594...91,759,033
G
Chrm5
cholinergic receptor, muscarinic 5
increases expression
ISO
Dieldrin results in increased expression of CHRM5 mRNA
CTD
PMID:18812211
NCBI chr 2:112,306,055...112,365,487
Ensembl chr 2:112,309,516...112,311,114
G
Chrna1
cholinergic receptor nicotinic alpha 1 subunit
decreases expression
ISO
Dieldrin results in decreased expression of CHRNA1 mRNA
CTD
PMID:23153324
NCBI chr 2:73,393,625...73,410,682
Ensembl chr 2:73,393,559...73,410,682
G
Chrna2
cholinergic receptor nicotinic alpha 2 subunit
decreases expression
ISO
Dieldrin results in decreased expression of CHRNA2 mRNA
CTD
PMID:18812211
NCBI chr14:66,370,685...66,390,397
Ensembl chr14:66,372,488...66,390,397
G
Chrna3
cholinergic receptor, nicotinic, alpha polypeptide 3
decreases expression
ISO
Dieldrin results in decreased expression of CHRNA3 mRNA
CTD
PMID:18812211
NCBI chr 9:54,917,401...54,933,846
Ensembl chr 9:54,917,395...54,933,846
G
Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
affects expression
ISO
Dieldrin affects the expression of CHRNA4 mRNA
CTD
PMID:18812211
NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
G
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
decreases expression
ISO
Dieldrin results in decreased expression of CHRNA5 mRNA
CTD
PMID:18812211
NCBI chr 9:54,888,112...54,918,704
Ensembl chr 9:54,888,164...54,915,063
G
Chrna7
cholinergic receptor, nicotinic, alpha polypeptide 7
increases expression
ISO
Dieldrin results in increased expression of CHRNA7 mRNA
CTD
PMID:18812211
NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317
G
Chrnb4
cholinergic receptor, nicotinic, beta polypeptide 4
decreases expression
ISO
Dieldrin results in decreased expression of CHRNB4 mRNA
CTD
PMID:18812211
NCBI chr 9:54,935,438...54,956,236
Ensembl chr 9:54,935,438...54,956,063
G
Cidea
cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
affects expression
ISO
Dieldrin affects the expression of CIDEA mRNA
CTD
PMID:22546817
NCBI chr18:67,476,634...67,500,864
Ensembl chr18:67,476,674...67,500,855
G
Cit
citron
affects expression
ISO
Dieldrin affects the expression of CIT mRNA
CTD
PMID:22546817
NCBI chr 5:115,983,284...116,147,012
Ensembl chr 5:115,983,337...116,147,006
G
Cldn2
claudin 2
decreases expression
ISO
Dieldrin results in decreased expression of CLDN2 mRNA
CTD
PMID:23153324
NCBI chr X:138,701,552...138,712,135
Ensembl chr X:138,701,577...138,712,135
G
Clk1
CDC-like kinase 1
affects expression
ISO
Dieldrin affects the expression of CLK1 mRNA
CTD
PMID:22546817
NCBI chr 1:58,451,147...58,463,247
Ensembl chr 1:58,449,348...58,463,225
G
Col18a1
collagen, type XVIII, alpha 1
affects expression
ISO
Dieldrin affects the expression of COL18A1 mRNA
CTD
PMID:22546817
NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382
G
Comt
catechol-O-methyltransferase
increases expression
ISO
Dieldrin results in increased expression of COMT mRNA
CTD
PMID:18812211
NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
G
Cort
cortistatin
affects expression
ISO
Dieldrin affects the expression of CORT mRNA
CTD
PMID:22546817
NCBI chr 4:149,209,491...149,211,132
Ensembl chr 4:149,209,491...149,211,220
G
Creb1
cAMP responsive element binding protein 1
increases phosphorylation
ISO
Dieldrin results in increased phosphorylation of CREB1 protein
CTD
PMID:31068361
NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
G
Crh
corticotropin releasing hormone
increases expression
ISO
Dieldrin results in increased expression of CRH mRNA
CTD
PMID:20682304
NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
G
Crk
v-crk avian sarcoma virus CT10 oncogene homolog
affects expression
ISO
Dieldrin affects the expression of CRK mRNA
CTD
PMID:22546817
NCBI chr11:75,570,020...75,599,254
Ensembl chr11:75,570,085...75,597,734
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Cse1l
chromosome segregation 1 like
affects expression
ISO
Dieldrin affects the expression of CSE1L mRNA
CTD
PMID:22546817
NCBI chr 2:166,747,961...166,788,309
Ensembl chr 2:166,747,960...166,788,309
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Csnk1d
casein kinase 1, delta
affects expression
ISO
Dieldrin affects the expression of CSNK1D mRNA
CTD
PMID:22546817
NCBI chr11:120,848,535...120,882,180
Ensembl chr11:120,849,816...120,882,156
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Csnk2a1
casein kinase 2, alpha 1 polypeptide
decreases response to substance
ISO
CSNK2A1 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 2:152,068,468...152,123,772
Ensembl chr 2:152,068,759...152,123,772
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Csrnp1
cysteine-serine-rich nuclear protein 1
increases expression
ISO
Dieldrin results in increased expression of CSRNP1 mRNA
CTD
PMID:31068361
NCBI chr 9:119,800,229...119,813,808
Ensembl chr 9:119,800,229...119,813,724
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Cstb
cystatin B
affects expression
ISO
Dieldrin affects the expression of CSTB mRNA
CTD
PMID:22546817
NCBI chr10:78,261,504...78,263,456
Ensembl chr10:78,261,503...78,263,456
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Ctcf
CCCTC-binding factor
affects expression
ISO
Dieldrin affects the expression of CTCF mRNA
CTD
PMID:22546817
NCBI chr 8:106,351,135...106,409,554
Ensembl chr 8:106,363,200...106,409,554
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Cul1
cullin 1
affects expression
ISO
Dieldrin affects the expression of CUL1 mRNA
CTD
PMID:22546817
NCBI chr 6:47,430,516...47,503,078
Ensembl chr 6:47,430,332...47,503,073
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Cul2
cullin 2
affects expression
ISO
Dieldrin affects the expression of CUL2 mRNA
CTD
PMID:22546817
NCBI chr18:3,382,970...3,436,700
Ensembl chr18:3,382,988...3,436,377
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Cul5
cullin 5
affects expression
ISO
Dieldrin affects the expression of CUL5 mRNA
CTD
PMID:22546817
NCBI chr 9:53,525,881...53,578,807
Ensembl chr 9:53,525,882...53,581,314
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Cwf19l1
CWF19 like cell cycle control factor 1
affects expression
ISO
Dieldrin affects the expression of CWF19L1 mRNA
CTD
PMID:22546817
NCBI chr19:44,097,076...44,124,324
Ensembl chr19:44,097,076...44,124,315
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Cwf19l2
CWF19 like cell cycle control factor 2
affects expression
ISO
Dieldrin affects the expression of CWF19L2 mRNA
CTD
PMID:22546817
NCBI chr 9:3,403,592...3,479,236
Ensembl chr 9:3,403,592...3,479,236
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Cycs
cytochrome c, somatic
multiple interactions affects localization
ISO
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Dieldrin affects the localization of CYCS protein]
CTD
PMID:12831855
NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
ISO
Dieldrin results in increased expression of CYP1A1 mRNA
CTD
PMID:10910964
NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression
ISO
Dieldrin results in increased expression of CYP1A2 mRNA
CTD
PMID:10910964
NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
increases expression
ISO
Dieldrin results in increased expression of CYP1B1 mRNA
CTD
PMID:10910964
NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
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Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
multiple interactions increases expression
ISO
AGN 193109 inhibits the reaction [Dieldrin results in increased expression of CYP26A1 mRNA]
CTD
PMID:15589975
NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984
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Cyp2b10
cytochrome P450, family 2, subfamily b, polypeptide 10
multiple interactions increases expression
EXP ISO
NR1I3 protein affects the reaction [Dieldrin results in increased expression of CYP2B10 mRNA] Dieldrin results in increased expression of CYP2B6 protein
CTD
PMID:12049174 PMID:15548381 PMID:32435917
NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
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Cyp3a11
cytochrome P450, family 3, subfamily a, polypeptide 11
increases expression multiple interactions
EXP
Dieldrin results in increased expression of CYP3A11 mRNA NR1I2 protein affects the reaction [Dieldrin results in increased expression of CYP3A11 mRNA]; NR1I3 protein affects the reaction [Dieldrin results in increased expression of CYP3A11 mRNA]
CTD
PMID:12049174 PMID:32435917
NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
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Cyp8b1
cytochrome P450, family 8, subfamily b, polypeptide 1
decreases expression
ISO
Dieldrin results in decreased expression of CYP8B1 mRNA
CTD
PMID:23153324
NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
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Dad1
defender against cell death 1
affects expression
ISO
Dieldrin affects the expression of DAD1 mRNA
CTD
PMID:22546817
NCBI chr14:54,472,942...54,491,386
Ensembl chr14:54,472,936...54,491,561
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Dap
death-associated protein
affects expression
ISO
Dieldrin affects the expression of DAP mRNA
CTD
PMID:22546817
NCBI chr15:31,224,531...31,274,484
Ensembl chr15:31,224,460...31,274,487
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Dap3
death associated protein 3
affects expression
ISO
Dieldrin affects the expression of DAP3 mRNA
CTD
PMID:22546817
NCBI chr 3:88,828,110...88,858,504
Ensembl chr 3:88,828,110...88,858,488
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Daxx
Fas death domain-associated protein
affects expression
ISO
Dieldrin affects the expression of DAXX mRNA
CTD
PMID:22546817
NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564
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Dbh
dopamine beta hydroxylase
decreases expression
ISO
Dieldrin results in decreased expression of DBH mRNA
CTD
PMID:18812211
NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212
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Ddit3
DNA-damage inducible transcript 3
affects expression increases expression
ISO
Dieldrin affects the expression of DDIT3 mRNA Dieldrin results in increased expression of DDIT3 mRNA
CTD
PMID:22546817 PMID:28844784 PMID:31068361
NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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Ddit4
DNA-damage-inducible transcript 4
affects expression
ISO
Dieldrin affects the expression of DDIT4 mRNA
CTD
PMID:22546817
NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
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Dedd
death effector domain-containing
affects expression
ISO
Dieldrin affects the expression of DEDD mRNA
CTD
PMID:22546817
NCBI chr 1:171,152,229...171,170,843
Ensembl chr 1:171,156,713...171,169,899
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Depdc5
DEP domain containing 5
increases response to substance
ISO
DEPDC5 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 5:33,020,996...33,151,581
Ensembl chr 5:33,021,045...33,151,580
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Dgat2
diacylglycerol O-acyltransferase 2
decreases expression
ISO
Dieldrin results in decreased expression of DGAT2 mRNA
CTD
PMID:31068361
NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
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Dhx16
DEAH-box helicase 16
affects expression
ISO
Dieldrin affects the expression of DHX16 mRNA
CTD
PMID:22546817
NCBI chr17:36,190,657...36,203,562
Ensembl chr17:36,190,711...36,203,562
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Diablo
diablo, IAP-binding mitochondrial protein
affects expression
ISO
Dieldrin affects the expression of DIABLO mRNA
CTD
PMID:22546817
NCBI chr 5:123,649,393...123,664,825
Ensembl chr 5:123,647,828...123,662,239
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Dlg5
discs large MAGUK scaffold protein 5
affects expression
ISO
Dieldrin affects the expression of DLG5 mRNA
CTD
PMID:22546817
NCBI chr14:24,184,021...24,295,988
Ensembl chr14:24,184,021...24,295,988
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Dlgap5
DLG associated protein 5
affects expression
ISO
Dieldrin affects the expression of DLGAP5 mRNA
CTD
PMID:22546817
NCBI chr14:47,625,238...47,655,657
Ensembl chr14:47,625,236...47,655,864
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Dnajb1
DnaJ heat shock protein family (Hsp40) member B1
increases expression
ISO
Dieldrin results in increased expression of DNAJB1 mRNA
CTD
PMID:31068361
NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282
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Dnajb9
DnaJ heat shock protein family (Hsp40) member B9
affects expression
ISO
Dieldrin affects the expression of DNAJB9 mRNA
CTD
PMID:22546817
NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109
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Dnase1l3
deoxyribonuclease 1-like 3
affects expression
ISO
Dieldrin affects the expression of DNASE1L3 mRNA
CTD
PMID:22546817
NCBI chr14:14,475,014...14,504,586
Ensembl chr14:14,475,200...14,505,240
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Dnase2a
deoxyribonuclease II alpha
affects expression
ISO
Dieldrin affects the expression of DNASE2 mRNA
CTD
PMID:22546817
NCBI chr 8:85,635,384...85,638,332
Ensembl chr 8:85,635,189...85,649,544
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Drd3
dopamine receptor D3
increases expression
ISO
Dieldrin results in increased expression of DRD3 mRNA
CTD
PMID:18812211
NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295
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Drd4
dopamine receptor D4
decreases expression
ISO
Dieldrin results in decreased expression of DRD4 mRNA
CTD
PMID:18812211
NCBI chr 7:140,871,931...140,874,868
Ensembl chr 7:140,871,919...140,876,377
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Dst
dystonin
affects expression
ISO
Dieldrin affects the expression of DST mRNA
CTD
PMID:22546817
NCBI chr 1:33,946,969...34,347,743
Ensembl chr 1:33,947,306...34,347,742
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Dtymk
deoxythymidylate kinase
affects expression
ISO
Dieldrin affects the expression of DTYMK mRNA
CTD
PMID:22546817
NCBI chr 1:93,720,298...93,730,246
Ensembl chr 1:93,720,298...93,729,656
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Dusp1
dual specificity phosphatase 1
affects expression increases expression
ISO
Dieldrin affects the expression of DUSP1 mRNA Dieldrin results in increased expression of DUSP1 mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
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Dusp2
dual specificity phosphatase 2
increases expression
ISO
Dieldrin results in increased expression of DUSP2 mRNA
CTD
PMID:31068361
NCBI chr 2:127,178,079...127,180,297
Ensembl chr 2:127,178,079...127,180,296
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Dusp22
dual specificity phosphatase 22
affects expression
ISO
Dieldrin affects the expression of DUSP22 mRNA
CTD
PMID:22546817
NCBI chr13:30,844,042...30,895,215
Ensembl chr13:30,843,982...30,895,214
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E2f1
E2F transcription factor 1
affects expression increases expression
ISO
Dieldrin affects the expression of E2F1 mRNA Dieldrin results in increased expression of E2F1 mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
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E2f5
E2F transcription factor 5
affects expression
ISO
Dieldrin affects the expression of E2F5 mRNA
CTD
PMID:22546817
NCBI chr 3:14,638,370...14,671,369
Ensembl chr 3:14,643,701...14,671,369
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E2f8
E2F transcription factor 8
increases expression
ISO
Dieldrin results in increased expression of E2F8 mRNA
CTD
PMID:23153324
NCBI chr 7:48,516,177...48,531,821
Ensembl chr 7:48,516,177...48,531,344
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Ebag9
estrogen receptor-binding fragment-associated gene 9
affects expression
ISO
Dieldrin affects the expression of EBAG9 mRNA
CTD
PMID:22546817
NCBI chr15:44,482,574...44,504,916
Ensembl chr15:44,482,571...44,504,911
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Ect2
ect2 oncogene
increases expression
ISO
Dieldrin results in increased expression of ECT2 mRNA
CTD
PMID:23153324
NCBI chr 3:27,151,371...27,207,971
Ensembl chr 3:27,151,371...27,208,027
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Egfr
epidermal growth factor receptor
affects expression
ISO
Dieldrin affects the expression of EGFR mRNA
CTD
PMID:22546817
NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
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Egln3
egl-9 family hypoxia-inducible factor 3
affects expression
ISO
Dieldrin affects the expression of EGLN3 mRNA
CTD
PMID:22546817
NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646
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Egr1
early growth response 1
increases expression
ISO
Dieldrin results in increased expression of EGR1 mRNA
CTD
PMID:31068361
NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
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Egr2
early growth response 2
increases expression
ISO
Dieldrin results in increased expression of EGR2 mRNA
CTD
PMID:31068361
NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
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Ehbp1l1
EH domain binding protein 1-like 1
decreases expression
ISO
Dieldrin results in decreased expression of EHBP1L1 mRNA
CTD
PMID:31068361
NCBI chr19:5,757,397...5,776,504
Ensembl chr19:5,757,404...5,776,345
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Eif2ak4
eukaryotic translation initiation factor 2 alpha kinase 4
increases response to substance
ISO
EIF2AK4 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 2:118,219,065...118,305,715
Ensembl chr 2:118,219,099...118,305,715
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Eif4a1
eukaryotic translation initiation factor 4A1
decreases expression
ISO
Dieldrin results in decreased expression of EIF4A1 mRNA
CTD
PMID:34051100
NCBI chr11:69,557,762...69,563,249
Ensembl chr11:69,557,762...69,563,249
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Elk1
ELK1, member of ETS oncogene family
affects expression
ISO
Dieldrin affects the expression of ELK1 mRNA
CTD
PMID:22546817
NCBI chr X:20,799,634...20,816,847
Ensembl chr X:20,799,634...20,816,847
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Elovl7
ELOVL fatty acid elongase 7
increases expression
ISO
Dieldrin results in increased expression of ELOVL7 mRNA
CTD
PMID:23153324
NCBI chr13:108,350,860...108,423,643
Ensembl chr13:108,350,938...108,422,217
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Epha3
Eph receptor A3
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA3 mRNA
CTD
PMID:28263720
NCBI chr16:63,363,895...63,684,538
Ensembl chr16:63,363,897...63,684,538
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Epha8
Eph receptor A8
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNA
CTD
PMID:28263720
NCBI chr 4:136,656,729...136,684,170
Ensembl chr 4:136,656,730...136,684,127
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Ephx1
epoxide hydrolase 1, microsomal
multiple interactions
EXP
Dieldrin promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]
CTD
PMID:2043152
NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
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Ephx2
epoxide hydrolase 2, cytoplasmic
multiple interactions
EXP
Dieldrin promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]
CTD
PMID:2043152
NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
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Eral1
Era like 12S mitochondrial rRNA chaperone 1
affects expression
ISO
Dieldrin affects the expression of ERAL1 mRNA
CTD
PMID:22546817
NCBI chr11:77,964,202...77,971,209
Ensembl chr11:77,964,202...77,971,209
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Erbb3
erb-b2 receptor tyrosine kinase 3
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ERBB3 mRNA
CTD
PMID:19422813
NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521
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Erf
Ets2 repressor factor
affects expression
ISO
Dieldrin affects the expression of ERF mRNA
CTD
PMID:22546817
NCBI chr 7:24,941,985...24,950,522
Ensembl chr 7:24,941,986...24,950,186
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Espl1
extra spindle pole bodies 1, separase
affects expression
ISO
Dieldrin affects the expression of ESPL1 mRNA
CTD
PMID:22546817
NCBI chr15:102,204,688...102,232,792
Ensembl chr15:102,204,701...102,232,792
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Esr1
estrogen receptor 1 (alpha)
multiple interactions affects binding increases activity decreases expression increases expression
ISO EXP
[DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA; [Dieldrin co-treated with alachlor] inhibits the reaction [Estradiol binds to ESR1 protein]; [Dieldrin co-treated with Chlordan] inhibits the reaction [Estradiol binds to ESR1 protein]; [o,p'-DDT co-treated with Methoxychlor co-treated with Dieldrin] results in increased expression of ESR1 mRNA; [Toxaphene co-treated with Dieldrin co-treated with Chlordan] inhibits the reaction [Estradiol binds to ESR1 protein]; Dieldrin binds to and results in increased activity of ESR1 protein; Dieldrin inhibits the reaction [Estradiol binds to ESR1 protein]; Dieldrin inhibits the reaction [Estradiol results in decreased expression of ESR1 mRNA] Dieldrin binds to ESR1 protein Dieldrin results in increased activity of ESR1 protein Dieldrin results in decreased expression of ESR1 protein Dieldrin results in increased expression of ESR1 mRNA
CTD
PMID:9168004 PMID:10774817 PMID:11922773 PMID:14579009 PMID:15064155 PMID:15261991 PMID:16626760 PMID:17174995 PMID:21278053 PMID:21295777 PMID:26022396 More...
NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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Esr2
estrogen receptor 2 (beta)
multiple interactions
ISO EXP
Dieldrin binds to and results in decreased activity of ESR2 protein; Dieldrin promotes the reaction [Estradiol results in increased expression of ESR2 mRNA] Dieldrin inhibits the reaction [Estradiol binds to ESR2 protein]
CTD
PMID:15261991 PMID:16626760 PMID:21278053
NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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Esyt1
extended synaptotagmin-like protein 1
decreases expression
ISO
Dieldrin results in decreased expression of ESYT1 mRNA
CTD
PMID:31068361
NCBI chr10:128,346,117...128,361,728
Ensembl chr10:128,345,834...128,361,740
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Fadd
Fas associated via death domain
affects expression
ISO
Dieldrin affects the expression of FADD mRNA
CTD
PMID:22546817
NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
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Faf1
Fas-associated factor 1
affects expression
ISO
Dieldrin affects the expression of FAF1 mRNA
CTD
PMID:22546817
NCBI chr 4:109,533,873...109,821,157
Ensembl chr 4:109,533,785...109,821,157
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Faim2
Fas apoptotic inhibitory molecule 2
affects expression
ISO
Dieldrin affects the expression of FAIM2 mRNA
CTD
PMID:22546817
NCBI chr15:99,394,886...99,432,757
Ensembl chr15:99,394,893...99,426,046
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Fbxo2
F-box protein 2
affects expression
ISO
Dieldrin affects the expression of FBXO2 mRNA
CTD
PMID:22546817
NCBI chr 4:148,244,605...148,250,874
Ensembl chr 4:148,245,078...148,250,881
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Fbxw11
F-box and WD-40 domain protein 11
increases response to substance
ISO
FBXW11 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr11:32,592,595...32,696,816
Ensembl chr11:32,592,724...32,696,816
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Fem1b
fem 1 homolog b
affects expression
ISO
Dieldrin affects the expression of FEM1B mRNA
CTD
PMID:22546817
NCBI chr 9:62,699,106...62,718,930
Ensembl chr 9:62,699,103...62,719,216
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Fgf1
fibroblast growth factor 1
affects expression
ISO
Dieldrin affects the expression of FGF1 mRNA
CTD
PMID:19130878 PMID:22546817
NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525
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Fgf12
fibroblast growth factor 12
decreases expression
ISO
Dieldrin results in decreased expression of FGF12 mRNA
CTD
PMID:19130878
NCBI chr16:27,976,535...28,571,995
Ensembl chr16:27,978,850...28,571,820
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Fgf15
fibroblast growth factor 15
affects expression
ISO
Dieldrin affects the expression of FGF15 mRNA
CTD
PMID:19130878
NCBI chr 7:144,450,269...144,454,690
Ensembl chr 7:144,450,268...144,454,690
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Fgf17
fibroblast growth factor 17
decreases expression
ISO
Dieldrin results in decreased expression of FGF17 mRNA
CTD
PMID:19130878
NCBI chr14:70,873,643...70,880,064
Ensembl chr14:70,873,643...70,879,708
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Fgf2
fibroblast growth factor 2
decreases expression affects expression
ISO
Dieldrin results in decreased expression of FGF2 mRNA Dieldrin affects the expression of FGF2 mRNA
CTD
PMID:19130878 PMID:22546817
NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
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Fgf21
fibroblast growth factor 21
decreases expression
ISO
Dieldrin results in decreased expression of FGF21 mRNA
CTD
PMID:19130878
NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914
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Fgf22
fibroblast growth factor 22
increases expression
ISO
Dieldrin results in increased expression of FGF22 mRNA
CTD
PMID:19130878
NCBI chr10:79,590,887...79,593,629
Ensembl chr10:79,590,910...79,594,430
G
Fgf9
fibroblast growth factor 9
increases expression affects expression
ISO
Dieldrin results in increased expression of FGF9 mRNA Dieldrin affects the expression of FGF9 mRNA
CTD
PMID:19130878 PMID:22546817
NCBI chr14:58,308,543...58,350,311
Ensembl chr14:58,308,004...58,350,177
G
Fgfr1
fibroblast growth factor receptor 1
affects expression
ISO
Dieldrin affects the expression of FGFR1 mRNA
CTD
PMID:19130878
NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
G
Fgfr4
fibroblast growth factor receptor 4
affects expression
ISO
Dieldrin affects the expression of FGFR4 mRNA
CTD
PMID:19130878
NCBI chr13:55,300,631...55,316,572
Ensembl chr13:55,300,453...55,316,572
G
Fis1
fission, mitochondrial 1
affects expression
ISO
Dieldrin affects the expression of FIS1 mRNA
CTD
PMID:22546817
NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
G
Fos
FBJ osteosarcoma oncogene
multiple interactions increases expression
ISO
1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; BX795 promotes the reaction [Dieldrin results in increased expression of FOS mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; N-alpha-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; Wortmannin inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]
CTD
PMID:31068361
NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
G
Fosb
FBJ osteosarcoma oncogene B
increases expression
ISO
Dieldrin results in increased expression of FOSB mRNA
CTD
PMID:31068361
NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976
G
Fosl2
fos-like antigen 2
increases expression
ISO
Dieldrin results in increased expression of FOSL2 mRNA
CTD
PMID:31068361
NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
G
Foxn3
forkhead box N3
affects expression
ISO
Dieldrin affects the expression of FOXN3 mRNA
CTD
PMID:22546817
NCBI chr12:99,156,340...99,529,926
Ensembl chr12:99,156,337...99,529,841
G
Foxo3
forkhead box O3
affects expression
ISO
Dieldrin affects the expression of FOXO3 mRNA
CTD
PMID:22546817
NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
G
Fxr1
FMR1 autosomal homolog 1
affects expression
ISO
Dieldrin affects the expression of FXR1 mRNA
CTD
PMID:22546817
NCBI chr 3:34,074,133...34,124,129
Ensembl chr 3:34,074,092...34,124,471
G
Fyn
Fyn proto-oncogene
increases activity multiple interactions affects expression
ISO
Dieldrin results in increased activity of FYN protein FYN protein promotes the reaction [Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]]; FYN protein promotes the reaction [Dieldrin results in increased phosphorylation of PRKCD protein] Dieldrin affects the expression of FYN mRNA
CTD
PMID:21801747 PMID:22546817
NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377
G
Fzd1
frizzled class receptor 1
increases expression
ISO
Dieldrin results in increased expression of FZD1 mRNA
CTD
PMID:19130878
NCBI chr 5:4,803,839...4,808,216
Ensembl chr 5:4,803,839...4,808,035
G
Fzd2
frizzled class receptor 2
increases expression
ISO
Dieldrin results in increased expression of FZD2 mRNA
CTD
PMID:19130878
NCBI chr11:102,495,257...102,498,884
Ensembl chr11:102,495,222...102,498,884
G
Fzd3
frizzled class receptor 3
decreases expression
ISO
Dieldrin results in decreased expression of FZD3 mRNA
CTD
PMID:19130878
NCBI chr14:65,429,890...65,499,912
Ensembl chr14:65,429,898...65,499,912
G
Fzd6
frizzled class receptor 6
affects expression
ISO
Dieldrin affects the expression of FZD6 mRNA
CTD
PMID:19130878
NCBI chr15:38,869,673...38,901,587
Ensembl chr15:38,869,429...38,901,583
G
Fzd7
frizzled class receptor 7
affects expression
ISO
Dieldrin affects the expression of FZD7 mRNA
CTD
PMID:19130878
NCBI chr 1:59,521,306...59,526,114
Ensembl chr 1:59,521,583...59,526,114
G
Fzd9
frizzled class receptor 9
decreases expression
ISO
Dieldrin results in decreased expression of FZD9 mRNA
CTD
PMID:19130878
NCBI chr 5:135,277,792...135,279,901
Ensembl chr 5:135,277,792...135,280,084
G
Fzr1
fizzy and cell division cycle 20 related 1
affects expression
ISO
Dieldrin affects the expression of FZR1 mRNA
CTD
PMID:22546817
NCBI chr10:81,202,713...81,214,204
Ensembl chr10:81,202,056...81,214,350
G
G6pdx
glucose-6-phosphate dehydrogenase X-linked
affects expression
ISO
Dieldrin affects the expression of G6PD mRNA
CTD
PMID:22546817
NCBI chr X:73,453,089...73,472,486
Ensembl chr X:73,453,089...73,472,800
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions decreases expression
ISO
Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] Dieldrin results in decreased expression of GABRA1 mRNA
CTD
PMID:9600394 PMID:14637376
NCBI chr11:42,021,766...42,073,893
Ensembl chr11:42,021,766...42,073,757
G
Gabra2
gamma-aminobutyric acid type A receptor subunit alpha 2
multiple interactions
ISO
Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:14637376
NCBI chr 5:71,115,735...71,253,192
Ensembl chr 5:71,114,940...71,253,192
G
Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
multiple interactions
ISO
Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:14637376
NCBI chr11:42,310,342...42,523,418
Ensembl chr11:42,310,584...42,519,855
G
Gabrb3
GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3
decreases expression increases expression
ISO
Dieldrin results in decreased expression of GABRB3 mRNA Dieldrin results in increased expression of GABRB3 mRNA
CTD
PMID:9302086 PMID:9600394
NCBI chr 7:57,240,266...57,478,550
Ensembl chr 7:57,069,440...57,478,550
G
Gabrg1
gamma-aminobutyric acid type A receptor subunit gamma 1
decreases expression
ISO
Dieldrin results in decreased expression of GABRG1 mRNA
CTD
PMID:9600394
NCBI chr 5:70,906,512...70,999,960
Ensembl chr 5:70,908,390...70,999,960
G
Gabrg2
gamma-aminobutyric acid type A receptor, subunit gamma 2
multiple interactions decreases expression
ISO
Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] Dieldrin results in decreased expression of GABRG2 mRNA
CTD
PMID:9302086 PMID:14637376
NCBI chr11:41,801,017...41,891,684
Ensembl chr11:41,801,030...41,891,684
G
Gabrr1
gamma-aminobutyric acid type A receptor subunit rho 1
affects binding
ISO
Dieldrin binds to GABRR1 protein
CTD
PMID:11879973
NCBI chr 4:33,132,556...33,163,606
Ensembl chr 4:33,132,521...33,163,588
G
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
affects expression
ISO
Dieldrin affects the expression of GADD45A mRNA
CTD
PMID:22546817
NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
G
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
affects expression
ISO
Dieldrin affects the expression of GADD45G mRNA
CTD
PMID:22546817
NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504
G
Galnt3
polypeptide N-acetylgalactosaminyltransferase 3
increases expression
ISO
Dieldrin results in increased expression of GALNT3 mRNA
CTD
PMID:31068361
NCBI chr 2:65,913,110...65,955,217
Ensembl chr 2:65,913,110...65,955,338
G
Gap43
growth associated protein 43
multiple interactions
ISO
Dieldrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]
CTD
PMID:28385489
NCBI chr16:42,068,915...42,161,014
Ensembl chr16:42,068,805...42,161,014
G
Get1
guided entry of tail-anchored proteins factor 1
decreases expression
ISO
Dieldrin results in decreased expression of WRB mRNA
CTD
PMID:31068361
NCBI chr16:95,946,600...95,959,052
Ensembl chr16:95,946,607...95,959,052
G
Gfap
glial fibrillary acidic protein
multiple interactions
EXP
Dieldrin promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]
CTD
PMID:16809432
NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
G
Gfi1b
growth factor independent 1B
affects expression
ISO
Dieldrin affects the expression of GFI1B mRNA
CTD
PMID:22546817
NCBI chr 2:28,499,462...28,511,994
Ensembl chr 2:28,499,462...28,511,994
G
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of GFRA1 mRNA
CTD
PMID:28263720
NCBI chr19:58,224,013...58,444,387
Ensembl chr19:58,224,036...58,444,341
G
Gja1
gap junction protein, alpha 1
multiple interactions decreases expression decreases phosphorylation
ISO
[Dieldrin co-treated with 2,4,5,2',4',5'-hexabromobiphenyl] results in decreased expression of GJA1 protein; [Dieldrin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of GJA1 protein Dieldrin results in decreased expression of GJA1 protein Dieldrin results in decreased expression of GJA1 mRNA; Dieldrin results in decreased expression of GJA1 protein; Dieldrin results in decreased expression of GJA1 protein modified form chaetoglobosins inhibits the reaction [Dieldrin results in decreased phosphorylation of GJA1 protein]
CTD
PMID:8068183 PMID:8820588 PMID:15082077 PMID:18040759
NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
G
Gjb2
gap junction protein, beta 2
decreases expression
ISO
Dieldrin results in decreased expression of GJB2 protein
CTD
PMID:8068183
NCBI chr14:57,336,059...57,342,159
Ensembl chr14:57,336,057...57,342,159
G
Gm7072
predicted gene 7072
increases expression
ISO
Dieldrin results in increased expression of ZNF34 mRNA
CTD
PMID:31068361
NCBI chr17:22,504,852...22,539,853
Ensembl chr17:22,504,852...22,533,818
G
Gnrh1
gonadotropin releasing hormone 1
affects expression
ISO
Dieldrin affects the expression of GNRH1 mRNA
CTD
PMID:22546817
NCBI chr14:67,982,717...67,986,889
Ensembl chr14:67,982,630...67,986,888
G
Gpx1
glutathione peroxidase 1
decreases expression multiple interactions affects expression
ISO EXP
Dieldrin results in decreased expression of GPX1 mRNA GPX1 protein results in decreased activity of and results in decreased susceptibility to Dieldrin Dieldrin affects the expression of GPX1 mRNA
CTD
PMID:12621067 PMID:19440498 PMID:22546817
NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
G
Gpx3
glutathione peroxidase 3
increases expression
ISO
Dieldrin results in increased expression of GPX3 mRNA
CTD
PMID:19440498
NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
G
Gpx4
glutathione peroxidase 4
increases expression
ISO
Dieldrin results in increased expression of GPX4 mRNA
CTD
PMID:19440498
NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
G
Gpx6
glutathione peroxidase 6
decreases expression
ISO
Dieldrin results in decreased expression of GPX6 mRNA
CTD
PMID:19440498
NCBI chr13:21,479,635...21,503,795
Ensembl chr13:21,496,295...21,503,794
G
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
increases expression
ISO
Dieldrin results in increased expression of GRIA1 mRNA
CTD
PMID:19440498
NCBI chr11:56,902,342...57,221,070
Ensembl chr11:56,902,213...57,221,070
G
Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
decreases expression
ISO
Dieldrin results in decreased expression of GRIA2 mRNA
CTD
PMID:19440498
NCBI chr 3:80,588,757...80,711,534
Ensembl chr 3:80,588,757...80,710,142
G
Grid1
glutamate receptor, ionotropic, delta 1
affects expression
ISO
Dieldrin affects the expression of GRID1 mRNA
CTD
PMID:19440498
NCBI chr14:34,541,751...35,305,344
Ensembl chr14:34,542,065...35,305,336
G
Grik3
glutamate receptor, ionotropic, kainate 3
decreases expression
ISO
Dieldrin results in decreased expression of GRIK3 mRNA
CTD
PMID:19440498
NCBI chr 4:125,384,025...125,607,966
Ensembl chr 4:125,384,493...125,607,966
G
Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
increases uptake increases expression
EXP ISO
Dieldrin results in increased uptake of GRIN1 protein Dieldrin results in increased expression of GRIN1 mRNA
CTD
PMID:19440498 PMID:19812363
NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199
G
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
decreases expression
ISO
Dieldrin results in decreased expression of GRIN2B mRNA
CTD
PMID:19440498
NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
G
Grin2c
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
affects expression
ISO
Dieldrin affects the expression of GRIN2C mRNA
CTD
PMID:19440498
NCBI chr11:115,139,995...115,158,123
Ensembl chr11:115,139,995...115,158,069
G
Grin3b
glutamate receptor, ionotropic, NMDA3B
affects expression
ISO
Dieldrin affects the expression of GRIN3B mRNA
CTD
PMID:19440498
NCBI chr10:79,806,227...79,813,024
Ensembl chr10:79,806,549...79,813,024
G
Grina
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
increases expression
ISO
Dieldrin results in increased expression of GRINA mRNA
CTD
PMID:19440498
NCBI chr15:76,130,917...76,134,109
Ensembl chr15:76,130,964...76,134,104
G
Grk2
G protein-coupled receptor kinase 2
increases expression
ISO
Dieldrin results in increased expression of GRK2 mRNA
CTD
PMID:18812211
NCBI chr19:4,336,029...4,356,356
Ensembl chr19:4,336,029...4,356,250
G
Grm5
glutamate receptor, metabotropic 5
decreases expression
EXP
Dieldrin results in decreased expression of GRM5 protein
CTD
PMID:19812363
NCBI chr 7:87,233,212...87,784,271
Ensembl chr 7:87,233,376...87,784,115
G
Gsta1
glutathione S-transferase, alpha 1 (Ya)
affects expression increases expression
ISO
Dieldrin affects the expression of GSTA5 mRNA Dieldrin results in increased expression of GSTA5 mRNA
CTD
PMID:19440498
NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
G
Gstm4
glutathione S-transferase, mu 4
affects expression
ISO
Dieldrin affects the expression of GSTM4 mRNA
CTD
PMID:19440498
NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210
G
Gstm5
glutathione S-transferase, mu 5
affects expression
ISO
Dieldrin affects the expression of GSTM3 mRNA
CTD
PMID:19440498
NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
G
Gsto1
glutathione S-transferase omega 1
increases expression
ISO
Dieldrin results in increased expression of GSTO1 mRNA
CTD
PMID:19440498
NCBI chr19:47,843,412...47,853,229
Ensembl chr19:47,843,409...47,853,229
G
Gsto2
glutathione S-transferase omega 2
affects expression
ISO
Dieldrin affects the expression of GSTO2 mRNA
CTD
PMID:19440498
NCBI chr19:47,853,879...47,874,747
Ensembl chr19:47,853,973...47,874,763
G
H2ac25
H2A clustered histone 25
increases expression
ISO
Dieldrin results in increased expression of H2AC25 mRNA
CTD
PMID:31068361
NCBI chr11:58,845,511...58,846,018
Ensembl chr11:58,845,511...58,847,656
G
H2ac4
H2A clustered histone 4
increases expression
ISO
Dieldrin results in increased expression of HIST1H2AC mRNA
CTD
PMID:31068361
NCBI chr13:23,935,061...23,935,577
Ensembl chr13:23,935,109...23,935,581
G
H2az1
H2A.Z variant histone 1
increases expression
ISO
Dieldrin results in increased expression of H2AZ1 mRNA
CTD
PMID:23153324
NCBI chr 3:137,570,248...137,572,683
Ensembl chr 3:137,570,248...137,572,683
G
Haus1
HAUS augmin-like complex, subunit 1
affects expression
ISO
Dieldrin affects the expression of HAUS1 mRNA
CTD
PMID:22546817
NCBI chr18:77,844,977...77,861,602
Ensembl chr18:77,845,267...77,861,586
G
Hibadh
3-hydroxyisobutyrate dehydrogenase
decreases expression
ISO
Dieldrin results in decreased expression of HIBADH mRNA
CTD
PMID:23153324
NCBI chr 6:52,523,215...52,617,285
Ensembl chr 6:52,523,213...52,617,374
G
Hipk1
homeodomain interacting protein kinase 1
affects expression
ISO
Dieldrin affects the expression of HIPK1 mRNA
CTD
PMID:22546817
NCBI chr 3:103,647,131...103,699,210
Ensembl chr 3:103,647,131...103,698,879
G
Hk2
hexokinase 2
increases expression
ISO
Dieldrin results in increased expression of HK2 mRNA
CTD
PMID:23153324
NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435
G
Hmox1
heme oxygenase 1
multiple interactions increases expression affects expression
EXP ISO
Dieldrin results in increased expression of and results in increased activity of HMOX1 protein; SB 203580 inhibits the reaction [Dieldrin results in increased expression of HMOX1 protein] Dieldrin results in increased expression of HMOX1 mRNA Dieldrin affects the expression of HMOX1 mRNA
CTD
PMID:11181820 PMID:15770161 PMID:22546817
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
G
Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
affects expression
ISO
Dieldrin affects the expression of HRK mRNA
CTD
PMID:22546817
NCBI chr 5:118,307,829...118,327,543
Ensembl chr 5:118,302,713...118,327,543
G
Hspa1a
heat shock protein 1A
affects expression
ISO
Dieldrin affects the expression of HSPA1A mRNA
CTD
PMID:22546817
NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
G
Hspa1b
heat shock protein 1B
increases expression
ISO
Dieldrin results in increased expression of HSPA1B mRNA
CTD
PMID:31068361
NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
G
Hspa9
heat shock protein 9
affects expression
ISO
Dieldrin affects the expression of HSPA9 mRNA
CTD
PMID:22546817
NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410
G
Htr1a
5-hydroxytryptamine (serotonin) receptor 1A
decreases expression
ISO
Dieldrin results in decreased expression of HTR1A mRNA
CTD
PMID:18835401
NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630
G
Htr1d
5-hydroxytryptamine (serotonin) receptor 1D
affects expression
ISO
Dieldrin affects the expression of HTR1D mRNA
CTD
PMID:18835401
NCBI chr 4:136,150,835...136,171,716
Ensembl chr 4:136,150,835...136,171,709
G
Htr2b
5-hydroxytryptamine (serotonin) receptor 2B
affects expression
ISO
Dieldrin affects the expression of HTR2B mRNA
CTD
PMID:18835401
NCBI chr 1:86,025,268...86,043,960
Ensembl chr 1:86,026,748...86,039,692
G
Htr2c
5-hydroxytryptamine (serotonin) receptor 2C
affects expression
ISO
Dieldrin affects the expression of HTR2C mRNA
CTD
PMID:18835401
NCBI chr X:145,745,509...145,980,273
Ensembl chr X:145,745,509...145,980,273
G
Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
decreases expression
ISO
Dieldrin results in decreased expression of HTR3A mRNA
CTD
PMID:18835401
NCBI chr 9:48,810,513...48,822,451
Ensembl chr 9:48,810,513...48,822,399
G
Htr3b
5-hydroxytryptamine (serotonin) receptor 3B
decreases expression
ISO
Dieldrin results in decreased expression of HTR3B mRNA
CTD
PMID:18835401
NCBI chr 9:48,846,308...48,876,290
Ensembl chr 9:48,846,308...48,876,290
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Htr5a
5-hydroxytryptamine (serotonin) receptor 5A
increases expression
ISO
Dieldrin results in increased expression of HTR5A mRNA
CTD
PMID:18835401
NCBI chr 5:28,046,836...28,059,403
Ensembl chr 5:28,047,147...28,060,086
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Htr5b
5-hydroxytryptamine (serotonin) receptor 5B
decreases expression
ISO
Dieldrin results in decreased expression of HTR5B mRNA
CTD
PMID:18835401
NCBI chr 1:121,437,487...121,458,351
Ensembl chr 1:121,437,571...121,456,194
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Htr6
5-hydroxytryptamine (serotonin) receptor 6
affects expression
ISO
Dieldrin affects the expression of HTR6 mRNA
CTD
PMID:18835401
NCBI chr 4:138,787,017...138,802,881
Ensembl chr 4:138,788,419...138,802,881
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Icos
inducible T cell co-stimulator
increases expression
ISO
Dieldrin results in increased expression of ICOS mRNA
CTD
PMID:31068361
NCBI chr 1:60,999,909...61,039,481
Ensembl chr 1:61,017,086...61,039,479
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Id2
inhibitor of DNA binding 2
affects expression
ISO
Dieldrin affects the expression of ID2 mRNA
CTD
PMID:22546817
NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
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Idh3b
isocitrate dehydrogenase 3 (NAD+) beta
affects expression
ISO
Dieldrin affects the expression of IDH3B mRNA
CTD
PMID:22546817
NCBI chr 2:130,121,229...130,126,371
Ensembl chr 2:130,121,229...130,126,467
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Ier2
immediate early response 2
increases expression
ISO
Dieldrin results in increased expression of IER2 mRNA
CTD
PMID:31068361
NCBI chr 8:85,387,960...85,389,481
Ensembl chr 8:85,387,960...85,389,483
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Ier3
immediate early response 3
increases expression
ISO
Dieldrin results in increased expression of IER3 mRNA
CTD
PMID:31068361
NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
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Ifi35
interferon-induced protein 35
decreases expression
ISO
Dieldrin results in decreased expression of IFI35 mRNA
CTD
PMID:34051100
NCBI chr11:101,339,238...101,349,527
Ensembl chr11:101,339,233...101,349,524
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Ifi44
interferon-induced protein 44
decreases expression
ISO
Dieldrin results in decreased expression of IFI44 mRNA
CTD
PMID:34051100
NCBI chr 3:151,436,559...151,455,580
Ensembl chr 3:151,436,559...151,455,597
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Ifih1
interferon induced with helicase C domain 1
decreases expression
ISO
Dieldrin results in decreased expression of IFIH1 mRNA
CTD
PMID:34051100
NCBI chr 2:62,426,137...62,476,599
Ensembl chr 2:62,426,142...62,476,599
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Ifit2
interferon-induced protein with tetratricopeptide repeats 2
multiple interactions decreases expression
ISO
Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA]]; Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA] Dieldrin results in decreased expression of IFIT2 mRNA
CTD
PMID:34051100
NCBI chr19:34,527,961...34,553,934
Ensembl chr19:34,528,094...34,553,819
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
decreases expression
ISO
Dieldrin results in decreased expression of IFIT3 mRNA
CTD
PMID:34051100
NCBI chr19:34,560,519...34,566,382
Ensembl chr19:34,560,931...34,566,131
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Ifitm1
interferon induced transmembrane protein 1
affects expression
ISO
Dieldrin affects the expression of IFITM1 mRNA
CTD
PMID:22546817
NCBI chr 7:140,547,342...140,549,740
Ensembl chr 7:140,547,134...140,549,738
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Ifitm3
interferon induced transmembrane protein 3
decreases expression
ISO
Dieldrin results in decreased expression of IFITM3 mRNA
CTD
PMID:34051100
NCBI chr 7:140,589,503...140,590,657
Ensembl chr 7:140,589,499...140,590,683
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Igf1
insulin-like growth factor 1
affects expression
ISO
Dieldrin affects the expression of IGF1 mRNA
CTD
PMID:22546817
NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
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Il10
interleukin 10
affects expression
ISO
Dieldrin affects the expression of IL10 mRNA
CTD
PMID:22546817
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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Il18
interleukin 18
affects expression
ISO
Dieldrin affects the expression of IL18 mRNA
CTD
PMID:22546817
NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
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Il1b
interleukin 1 beta
increases expression
ISO
Dieldrin results in increased expression of IL1B mRNA
CTD
PMID:15135310
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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Il2
interleukin 2
increases expression
ISO
Dieldrin results in increased expression of IL2 mRNA
CTD
PMID:31068361
NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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Il6
interleukin 6
increases expression
ISO
Dieldrin results in increased expression of IL6 protein
CTD
PMID:13129777
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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Inpp5d
inositol polyphosphate-5-phosphatase D
affects expression
ISO
Dieldrin affects the expression of INPP5D mRNA
CTD
PMID:22546817
NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229
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Insig2
insulin induced gene 2
decreases expression
ISO
Dieldrin results in decreased expression of INSIG2 mRNA
CTD
PMID:23153324
NCBI chr 1:121,232,082...121,260,391
Ensembl chr 1:121,232,082...121,260,318
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Irak3
interleukin-1 receptor-associated kinase 3
affects expression
ISO
Dieldrin affects the expression of IRAK3 mRNA
CTD
PMID:22546817
NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035
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Irf7
interferon regulatory factor 7
decreases expression
ISO
Dieldrin results in decreased expression of IRF7 mRNA
CTD
PMID:34051100
NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394
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Irf9
interferon regulatory factor 9
decreases expression
ISO
Dieldrin results in decreased expression of IRF9 mRNA
CTD
PMID:34051100
NCBI chr14:55,841,442...55,847,487
Ensembl chr14:55,841,028...55,847,487
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Irgm1
immunity-related GTPase family M member 1
decreases expression
ISO
Dieldrin results in decreased expression of IRGM mRNA
CTD
PMID:34051100
NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510
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Isg15
ISG15 ubiquitin-like modifier
affects expression decreases expression
ISO
Dieldrin affects the expression of ISG15 mRNA Dieldrin results in decreased expression of ISG15 mRNA
CTD
PMID:22546817 PMID:34051100
NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253
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Isg20
interferon-stimulated protein
decreases expression
ISO
Dieldrin results in decreased expression of ISG20 mRNA
CTD
PMID:34051100
NCBI chr 7:78,561,136...78,570,144
Ensembl chr 7:78,563,172...78,570,144
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Itm2b
integral membrane protein 2B
affects expression
ISO
Dieldrin affects the expression of ITM2B mRNA
CTD
PMID:22546817
NCBI chr14:73,599,666...73,622,729
Ensembl chr14:73,599,666...73,622,729
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Jak2
Janus kinase 2
decreases expression
ISO
Dieldrin results in decreased expression of JAK2 mRNA
CTD
PMID:34051100
NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
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Jmjd6
jumonji domain containing 6
affects expression
ISO
Dieldrin affects the expression of JMJD6 mRNA
CTD
PMID:22546817
NCBI chr11:116,728,258...116,734,593
Ensembl chr11:116,728,258...116,734,275
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Jun
jun proto-oncogene
increases phosphorylation affects expression decreases response to substance increases expression
ISO
Dieldrin results in increased phosphorylation of JUN protein Dieldrin affects the expression of JUN mRNA JUN gene mutant form results in decreased susceptibility to Dieldrin Dieldrin results in increased expression of JUN mRNA
CTD
PMID:15888667 PMID:22546817 PMID:31068361 PMID:32421776
NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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Junb
jun B proto-oncogene
affects expression increases expression
ISO
Dieldrin affects the expression of JUNB mRNA Dieldrin results in increased expression of JUNB mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
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Jund
jun D proto-oncogene
affects expression increases expression
ISO
Dieldrin affects the expression of JUND mRNA Dieldrin results in increased expression of JUND mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265
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Katna1
katanin p60 (ATPase-containing) subunit A1
affects expression
ISO
Dieldrin affects the expression of KATNA1 mRNA
CTD
PMID:22546817
NCBI chr10:7,601,748...7,638,913
Ensembl chr10:7,601,764...7,638,914
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Kif18b
kinesin family member 18B
increases expression
ISO
Dieldrin results in increased expression of KIF18B mRNA
CTD
PMID:23153324
NCBI chr11:102,796,344...102,815,960
Ensembl chr11:102,796,355...102,815,950
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Kif20b
kinesin family member 20B
affects expression
ISO
Dieldrin affects the expression of KIF20B mRNA
CTD
PMID:22546817
NCBI chr19:34,899,735...34,953,150
Ensembl chr19:34,899,761...34,953,145
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Kit
KIT proto-oncogene receptor tyrosine kinase
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA
CTD
PMID:19422813 PMID:28263720
NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
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Klf10
Kruppel-like transcription factor 10
affects expression
ISO
Dieldrin affects the expression of KLF10 mRNA
CTD
PMID:22546817
NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950
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Klf4
Kruppel-like transcription factor 4 (gut)
increases expression
ISO
Dieldrin results in increased expression of KLF4 mRNA
CTD
PMID:31068361
NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
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Klf6
Kruppel-like transcription factor 6
increases expression
ISO
Dieldrin results in increased expression of KLF6 mRNA
CTD
PMID:31068361
NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393
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Klf9
Kruppel-like transcription factor 9
decreases expression
ISO
Dieldrin results in decreased expression of KLF9 mRNA
CTD
PMID:23153324
NCBI chr19:23,118,590...23,145,493
Ensembl chr19:23,118,590...23,145,498
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Klhl42
kelch-like 42
decreases response to substance
ISO
KLHL42 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 6:146,990,783...147,014,276
Ensembl chr 6:146,992,877...147,014,276
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Klk1b3
kallikrein 1-related peptidase b3
increases expression
ISO
Dieldrin results in increased expression of KLK1B3 mRNA
CTD
PMID:19130878
NCBI chr 7:43,847,615...43,851,775
Ensembl chr 7:43,847,615...43,851,776
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Lamb1
laminin B1
increases expression
ISO
Dieldrin results in increased expression of LAMB1 mRNA
CTD
PMID:23153324
NCBI chr12:31,315,230...31,379,643
Ensembl chr12:31,315,233...31,379,643
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Lax1
lymphocyte transmembrane adaptor 1
increases expression
ISO
Dieldrin results in increased expression of LAX1 mRNA
CTD
PMID:31068361
NCBI chr 1:133,606,767...133,620,760
Ensembl chr 1:133,606,829...133,617,846
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Lcn2
lipocalin 2
affects expression
ISO
Dieldrin affects the expression of LCN2 mRNA
CTD
PMID:22546817
NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
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Ldlr
low density lipoprotein receptor
increases expression
ISO
Dieldrin results in increased expression of LDLR mRNA
CTD
PMID:31068361
NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
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Lgals12
lectin, galactose binding, soluble 12
affects expression
ISO
Dieldrin affects the expression of LGALS12 mRNA
CTD
PMID:22546817
NCBI chr19:7,574,021...7,584,601
Ensembl chr19:7,574,025...7,584,558
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Lgals7
lectin, galactose binding, soluble 7
affects expression
ISO
Dieldrin affects the expression of LGALS7 mRNA
CTD
PMID:22546817
NCBI chr 7:28,563,258...28,565,711
Ensembl chr 7:28,563,278...28,565,709
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Lgi1
leucine-rich repeat LGI family, member 1
affects expression
ISO
Dieldrin affects the expression of LGI1 mRNA
CTD
PMID:22546817
NCBI chr19:38,253,135...38,297,387
Ensembl chr19:38,252,984...38,300,662
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Litaf
LPS-induced TN factor
affects expression
ISO
Dieldrin affects the expression of LITAF mRNA
CTD
PMID:22546817
NCBI chr16:10,777,137...10,810,985
Ensembl chr16:10,777,139...10,884,021
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Lmbrd1
LMBR1 domain containing 1
decreases expression
ISO
Dieldrin results in decreased expression of LMBRD1 mRNA
CTD
PMID:23153324
NCBI chr 1:24,716,073...24,805,382
Ensembl chr 1:24,717,711...24,805,382
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Lmnb1
lamin B1
increases expression
ISO
Dieldrin results in increased expression of LMNB1 mRNA
CTD
PMID:23153324
NCBI chr18:56,840,885...56,886,496
Ensembl chr18:56,840,885...56,886,496
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Lmx1b
LIM homeobox transcription factor 1 beta
affects methylation
EXP
Dieldrin affects the methylation of LMX1B gene
CTD
PMID:30859219
NCBI chr 2:33,450,977...33,531,219
Ensembl chr 2:33,450,977...33,530,620
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Lncpint
long non-protein coding RNA, Trp53 induced transcript
increases expression
ISO
Dieldrin results in increased expression of LINC-PINT mRNA
CTD
PMID:31068361
NCBI chr 6:31,070,498...31,195,409
Ensembl chr 6:31,059,500...31,197,423
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Lrrc1
leucine rich repeat containing 1
increases expression
ISO
Dieldrin results in increased expression of LRRC1 mRNA
CTD
PMID:23153324
NCBI chr 9:77,338,103...77,453,749
Ensembl chr 9:77,338,105...77,452,152
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Lrrc2
leucine rich repeat containing 2
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA
CTD
PMID:28263720
NCBI chr 9:110,780,613...110,813,134
Ensembl chr 9:110,780,613...110,813,134
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Lsp1
lymphocyte specific 1
affects expression
ISO
Dieldrin affects the expression of LSP1 mRNA
CTD
PMID:22546817
NCBI chr 7:142,014,583...142,048,605
Ensembl chr 7:142,014,546...142,048,604
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Mafk
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
affects expression
ISO
Dieldrin affects the expression of MAFK mRNA
CTD
PMID:22546817
NCBI chr 5:139,777,291...139,788,409
Ensembl chr 5:139,777,268...139,788,408
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Mageh1
MAGE family member H1
affects expression
ISO
Dieldrin affects the expression of MAGEH1 mRNA
CTD
PMID:22546817
NCBI chr X:151,819,162...151,820,559
Ensembl chr X:151,819,162...151,820,571
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Map2
microtubule-associated protein 2
multiple interactions
ISO
Dieldrin promotes the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of MAP2 mRNA]
CTD
PMID:32949729
NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
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Map2k1
mitogen-activated protein kinase kinase 1
multiple interactions
ISO
Dieldrin results in increased phosphorylation of and results in increased activity of MAP2K1 protein
CTD
PMID:15888667
NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
G
Map2k2
mitogen-activated protein kinase kinase 2
multiple interactions
ISO
Dieldrin results in increased phosphorylation of and results in increased activity of MAP2K2 protein
CTD
PMID:15888667
NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
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Map3k10
mitogen-activated protein kinase kinase kinase 10
affects expression
ISO
Dieldrin affects the expression of MAP3K10 mRNA
CTD
PMID:22546817
NCBI chr 7:27,355,800...27,374,059
Ensembl chr 7:27,355,800...27,374,023
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Map3k14
mitogen-activated protein kinase kinase kinase 14
increases expression
ISO
Dieldrin results in increased expression of MAP3K14 mRNA
CTD
PMID:31068361
NCBI chr11:103,110,590...103,158,227
Ensembl chr11:103,110,588...103,158,298
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Map3k6
mitogen-activated protein kinase kinase kinase 6
affects expression
ISO
Dieldrin affects the expression of MAP3K6 mRNA
CTD
PMID:22546817
NCBI chr 4:132,965,290...132,980,240
Ensembl chr 4:132,968,129...132,980,240
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Mapk1
mitogen-activated protein kinase 1
multiple interactions increases phosphorylation
ISO EXP
calphostin C inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; Dieldrin results in increased phosphorylation of and results in increased activity of MAPK1 protein; geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein] 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole co-treated with 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; [Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein] Dieldrin promotes the reaction [[Colforsin co-treated with Rolipram co-treated with Picrotoxin] results in increased phosphorylation of MAPK1 protein]
CTD
PMID:15531431 PMID:15888667 PMID:17174995 PMID:18040759 PMID:21278053 PMID:35137321 More...
NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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Mapk12
mitogen-activated protein kinase 12
affects expression
ISO
Dieldrin affects the expression of MAPK12 mRNA
CTD
PMID:22546817
NCBI chr15:89,014,787...89,025,270
Ensembl chr15:89,014,787...89,024,906
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Mapk13
mitogen-activated protein kinase 13
affects expression
ISO
Dieldrin affects the expression of MAPK13 mRNA
CTD
PMID:22546817
NCBI chr17:28,988,260...28,997,678
Ensembl chr17:28,988,271...28,999,207
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Mapk3
mitogen-activated protein kinase 3
multiple interactions increases phosphorylation affects expression
ISO EXP
calphostin C inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; Dieldrin results in increased phosphorylation of and results in increased activity of MAPK3 protein; geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein] 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole co-treated with 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; [Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein] Dieldrin affects the expression of MAPK3 mRNA Dieldrin promotes the reaction [[Colforsin co-treated with Rolipram co-treated with Picrotoxin] results in increased phosphorylation of MAPK3 protein]
CTD
PMID:15531431 PMID:15888667 PMID:18040759 PMID:21278053 PMID:22546817 PMID:35137321 More...
NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
affects expression
ISO
Dieldrin affects the expression of MAPK8IP1 mRNA
CTD
PMID:22546817
NCBI chr 2:92,214,021...92,231,608
Ensembl chr 2:92,214,021...92,231,608
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Mcl1
myeloid cell leukemia sequence 1
increases expression
ISO
Dieldrin results in increased expression of MCL1 mRNA
CTD
PMID:31068361
NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
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Mcoln2
mucolipin 2
affects response to substance
ISO
MCOLN2 gene SNP affects the susceptibility to Dieldrin
CTD
PMID:25622337
NCBI chr 3:145,855,552...145,901,269
Ensembl chr 3:145,855,588...145,901,268
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Mcrs1
microspherule protein 1
affects expression
ISO
Dieldrin affects the expression of MCRS1 mRNA
CTD
PMID:22546817
NCBI chr15:99,140,698...99,149,838
Ensembl chr15:99,140,698...99,149,842
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Mdc1
mediator of DNA damage checkpoint 1
affects expression
ISO
Dieldrin affects the expression of MDC1 mRNA
CTD
PMID:22546817
NCBI chr17:36,152,390...36,170,562
Ensembl chr17:36,152,407...36,170,562
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Mdk
midkine
affects expression
ISO
Dieldrin affects the expression of MDK mRNA
CTD
PMID:22546817
NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642
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Mdm2
transformed mouse 3T3 cell double minute 2
affects expression
ISO
Dieldrin affects the expression of MDM2 mRNA
CTD
PMID:22546817
NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
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Mdm4
transformed mouse 3T3 cell double minute 4
affects expression
ISO
Dieldrin affects the expression of MDM4 mRNA
CTD
PMID:22546817
NCBI chr 1:132,913,843...132,958,325
Ensembl chr 1:132,887,222...132,958,299
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Men1
multiple endocrine neoplasia 1
affects expression
ISO
Dieldrin affects the expression of MEN1 mRNA
CTD
PMID:22546817
NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921
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Mertk
MER proto-oncogene tyrosine kinase
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of MERTK mRNA
CTD
PMID:28263720
NCBI chr 2:128,540,836...128,645,082
Ensembl chr 2:128,540,876...128,644,814
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Mgst2
microsomal glutathione S-transferase 2
decreases expression
ISO
Dieldrin results in decreased expression of MGST2 mRNA
CTD
PMID:19440498
NCBI chr 3:51,544,179...51,590,096
Ensembl chr 3:51,567,781...51,590,098
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Mir24-2
microRNA 24-2
increases expression
ISO
Dieldrin results in increased expression of MIR24-2 mRNA
CTD
PMID:31068361
NCBI chr 8:84,935,444...84,935,550
Ensembl chr 8:84,935,444...84,935,550
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Mki67
antigen identified by monoclonal antibody Ki 67
affects expression
ISO
Dieldrin affects the expression of MKI67 mRNA
CTD
PMID:22546817
NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
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Mmd
monocyte to macrophage differentiation-associated
increases expression
ISO
Dieldrin results in increased expression of MMD mRNA
CTD
PMID:23153324
NCBI chr11:90,078,513...90,169,399
Ensembl chr11:90,140,282...90,169,415
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Mmp9
matrix metallopeptidase 9
increases expression
ISO
Dieldrin results in increased expression of MMP9 mRNA
CTD
PMID:23153324
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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Moap1
modulator of apoptosis 1
affects expression
ISO
Dieldrin affects the expression of MOAP1 mRNA
CTD
PMID:22546817
NCBI chr12:102,706,089...102,709,920
Ensembl chr12:102,708,489...102,709,920
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Mrtfa
myocardin related transcription factor A
affects expression
ISO
Dieldrin affects the expression of MRTFA mRNA
CTD
PMID:22546817
NCBI chr15:80,896,482...81,074,937
Ensembl chr15:80,896,482...81,074,958
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Msh2
mutS homolog 2
affects expression
ISO
Dieldrin affects the expression of MSH2 mRNA
CTD
PMID:22546817
NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
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mt-Tc
tRNA cysteine, mitochondrial
decreases expression
ISO
Dieldrin results in decreased expression of TRNC mRNA
CTD
PMID:31068361
NCBI chr MT:5,192...5,257
Ensembl chr MT:5,192...5,257
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mt-Tl1
tRNA leucine 1, mitochondrial
decreases expression
ISO
Dieldrin results in decreased expression of TRNL1 mRNA
CTD
PMID:31068361
NCBI chr MT:2,676...2,750
Ensembl chr MT:2,676...2,750
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mt-Tm
tRNA methionine, mitochondrial
decreases expression
ISO
Dieldrin results in decreased expression of TRNM mRNA
CTD
PMID:31068361
NCBI chr MT:3,845...3,913
Ensembl chr MT:3,845...3,913
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mt-Tt
tRNA threonine, mitochondrial
decreases expression
ISO
Dieldrin results in decreased expression of TRNT mRNA
CTD
PMID:31068361
NCBI chr MT:15,289...15,355
Ensembl chr MT:15,289...15,355
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mt-Ty
tRNA tyrosine, mitochondrial
decreases expression
ISO
Dieldrin results in decreased expression of TRNY mRNA
CTD
PMID:31068361
NCBI chr MT:5,260...5,326
Ensembl chr MT:5,260...5,326
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Mtch1
mitochondrial carrier 1
affects expression
ISO
Dieldrin affects the expression of MTCH1 mRNA
CTD
PMID:22546817
NCBI chr17:29,551,050...29,566,921
Ensembl chr17:29,551,046...29,566,908
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Mtor
mechanistic target of rapamycin kinase
increases phosphorylation
ISO
Dieldrin results in increased phosphorylation of MTOR protein
CTD
PMID:31068361
NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
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Mx1
MX dynamin-like GTPase 1
multiple interactions decreases expression
ISO
Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA]]; Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA] Dieldrin results in decreased expression of MX1 mRNA
CTD
PMID:34051100
NCBI chr16:97,248,235...97,264,106
Ensembl chr16:97,248,235...97,264,107
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Myadm
myeloid-associated differentiation marker
increases expression
ISO
Dieldrin results in increased expression of MYADM mRNA
CTD
PMID:31068361
NCBI chr 7:3,337,563...3,347,871
Ensembl chr 7:3,337,605...3,348,958
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Myc
myelocytomatosis oncogene
affects expression
ISO
Dieldrin affects the expression of MYC mRNA
CTD
PMID:22546817
NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
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Mycn
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
affects expression
ISO
Dieldrin affects the expression of MYCN mRNA
CTD
PMID:22546817
NCBI chr12:12,986,094...12,991,837
Ensembl chr12:12,986,094...12,991,915
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Nacc1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
affects expression
ISO
Dieldrin affects the expression of NACC1 mRNA
CTD
PMID:22546817
NCBI chr 8:85,397,106...85,414,528
Ensembl chr 8:85,397,108...85,414,531
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Nags
N-acetylglutamate synthase
decreases expression
ISO
Dieldrin results in decreased expression of NAGS mRNA
CTD
PMID:23153324
NCBI chr11:102,036,339...102,040,354
Ensembl chr11:102,036,339...102,040,303
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Nampt
nicotinamide phosphoribosyltransferase
affects expression
ISO
Dieldrin affects the expression of NAMPT mRNA
CTD
PMID:22546817
NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
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Nanog
Nanog homeobox
multiple interactions
ISO
Dieldrin inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in decreased expression of NANOG mRNA]
CTD
PMID:32949729
NCBI chr 6:122,684,448...122,691,592
Ensembl chr 6:122,684,448...122,691,592
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Ndc80
NDC80 kinetochore complex component
affects expression
ISO
Dieldrin affects the expression of NDC80 mRNA
CTD
PMID:22546817
NCBI chr17:71,803,095...71,833,852
Ensembl chr17:71,803,095...71,833,852
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Ndn
necdin, MAGE family member
affects expression
ISO
Dieldrin affects the expression of NDN mRNA
CTD
PMID:22546817
NCBI chr 7:61,998,025...61,999,676
Ensembl chr 7:61,996,317...62,000,010
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Neat1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
increases expression
ISO
Dieldrin results in increased expression of NEAT1 mRNA
CTD
PMID:31068361
NCBI chr19:5,874,736...5,895,508
Ensembl chr19:5,874,736...5,895,898
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Nedd8
neural precursor cell expressed, developmentally down-regulated gene 8
affects expression
ISO
Dieldrin affects the expression of NEDD8 mRNA
CTD
PMID:22546817
NCBI chr14:55,899,720...55,909,337
Ensembl chr14:55,899,720...55,909,581
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Nefh
neurofilament, heavy polypeptide
decreases expression
ISO
Dieldrin results in decreased expression of NEFH mRNA
CTD
PMID:18812211
NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
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Nefl
neurofilament, light polypeptide
increases expression
ISO
Dieldrin results in increased expression of NEFL mRNA
CTD
PMID:18812211
NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544
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Nefm
neurofilament, medium polypeptide
increases expression
ISO
Dieldrin results in increased expression of NEFM mRNA
CTD
PMID:18812211
NCBI chr14:68,356,994...68,362,453
Ensembl chr14:68,320,039...68,362,295
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Nek3
NIMA (never in mitosis gene a)-related expressed kinase 3
affects expression
ISO
Dieldrin affects the expression of NEK3 mRNA
CTD
PMID:22546817
NCBI chr 8:22,618,299...22,657,009
Ensembl chr 8:22,618,299...22,656,451
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Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
decreases phosphorylation
ISO
Dieldrin results in decreased phosphorylation of NFATC2 protein
CTD
PMID:31068361
NCBI chr 2:168,318,330...168,443,900
Ensembl chr 2:168,318,330...168,443,577
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Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
affects expression
ISO
Dieldrin affects the expression of NFKB1 mRNA
CTD
PMID:22546817
NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
increases expression
ISO
Dieldrin results in increased expression of NFKBIA mRNA
CTD
PMID:31068361
NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
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Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
increases expression
ISO
Dieldrin results in increased expression of NFKBID mRNA
CTD
PMID:31068361
NCBI chr 7:30,121,156...30,128,173
Ensembl chr 7:30,121,157...30,128,171
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Nfkbiz
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
increases expression
ISO
Dieldrin results in increased expression of NFKBIZ mRNA
CTD
PMID:31068361
NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262
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Nfu1
NFU1 iron-sulfur cluster scaffold
affects expression
ISO
Dieldrin affects the expression of NFU1 mRNA
CTD
PMID:22546817
NCBI chr 6:86,986,040...87,005,443
Ensembl chr 6:86,986,218...87,005,443
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Nfyc
nuclear transcription factor-Y gamma
affects expression
ISO
Dieldrin affects the expression of NFYC mRNA
CTD
PMID:22546817
NCBI chr 4:120,614,632...120,688,776
Ensembl chr 4:120,614,635...120,688,769
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Ngf
nerve growth factor
multiple interactions
EXP ISO
[Dieldrin co-treated with NGF protein] results in increased expression of SLC1A5 mRNA; [Dieldrin co-treated with NGF protein] results in increased expression of SLC7A11 mRNA Dieldrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]
CTD
PMID:20600679 PMID:28385489
NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
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Nnt
nicotinamide nucleotide transhydrogenase
decreases expression
ISO
Dieldrin results in decreased expression of NNT mRNA
CTD
PMID:23153324
NCBI chr13:119,472,063...119,545,793
Ensembl chr13:119,471,984...119,545,533 Ensembl chr13:119,471,984...119,545,533
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Nop2
NOP2 nucleolar protein
affects expression
ISO
Dieldrin affects the expression of NOP2 mRNA
CTD
PMID:22546817
NCBI chr 6:125,108,829...125,121,716
Ensembl chr 6:125,108,872...125,121,716
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Notch1
notch 1
affects expression
ISO
Dieldrin affects the expression of NOTCH1 mRNA
CTD
PMID:22546817
NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
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Notch2
notch 2
affects expression decreases expression
ISO
Dieldrin affects the expression of NOTCH2 mRNA Dieldrin results in decreased expression of NOTCH2 mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677
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Notch3
notch 3
decreases expression
ISO
Dieldrin results in decreased expression of NOTCH3 mRNA
CTD
PMID:31068361
NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826
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Nox1
NADPH oxidase 1
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Dieldrin] results in decreased expression of NOX1 protein
CTD
PMID:30240590
NCBI chr X:132,987,170...133,038,455
Ensembl chr X:132,987,170...133,122,705
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Npas4
neuronal PAS domain protein 4
increases expression
ISO
Dieldrin results in increased expression of NPAS4 mRNA
CTD
PMID:31068361
NCBI chr19:5,034,381...5,053,467
Ensembl chr19:5,034,383...5,040,344
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Npm1
nucleophosmin 1
affects expression
ISO
Dieldrin affects the expression of NPM1 mRNA
CTD
PMID:22546817
NCBI chr11:33,102,498...33,114,143
Ensembl chr11:33,102,287...33,113,206
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Nprl2
NPR2 like, GATOR1 complex subunit
increases response to substance
ISO
NPRL2 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 9:107,419,405...107,422,905
Ensembl chr 9:107,419,425...107,422,905
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Nprl3
nitrogen permease regulator-like 3
increases response to substance
ISO
NPRL3 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr11:32,181,963...32,217,707
Ensembl chr11:32,175,628...32,217,707
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Npy
neuropeptide Y
increases expression
ISO
Dieldrin results in increased expression of NPY mRNA
CTD
PMID:20682304
NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity multiple interactions
EXP ISO
Dieldrin results in increased activity of NR1I2 protein Dieldrin binds to and results in increased activity of NR1I2 protein; NR1I2 protein affects the reaction [Dieldrin results in increased expression of CYP3A11 mRNA] [DDT co-treated with Dieldrin] results in increased activity of NR1I2 protein; Dieldrin binds to and results in increased activity of NR1I2 protein; Dieldrin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA] [Dieldrin co-treated with NR1I2 protein] results in increased expression of PON1 mRNA; [Dieldrin co-treated with RXRA protein co-treated with NR1I2 protein] results in increased expression of PON1 mRNA
CTD
PMID:12049174 PMID:12417264 PMID:15548381 PMID:16054614 PMID:21115097 PMID:24615737 PMID:25028461 PMID:25680588 PMID:32435917 More...
NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
multiple interactions increases activity
EXP ISO
NR1I3 protein affects the reaction [Dieldrin results in increased expression of AOX1 mRNA]; NR1I3 protein affects the reaction [Dieldrin results in increased expression of CYP2B10 mRNA]; NR1I3 protein affects the reaction [Dieldrin results in increased expression of CYP3A11 mRNA] Dieldrin results in increased activity of NR1I3 protein
CTD
PMID:12049174 PMID:28927721 PMID:32435917
NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression
ISO
Dieldrin results in increased expression of NR4A1 mRNA
CTD
PMID:31068361
NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
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Nr4a2
nuclear receptor subfamily 4, group A, member 2
affects methylation increases expression
EXP ISO
Dieldrin affects the methylation of NR4A2 gene Dieldrin results in increased expression of NR4A2 mRNA
CTD
PMID:30859219 PMID:31068361
NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015
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Nr4a3
nuclear receptor subfamily 4, group A, member 3
increases expression
ISO
Dieldrin results in increased expression of NR4A3 mRNA
CTD
PMID:31068361
NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447
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Nradd
neurotrophin receptor associated death domain
affects expression
ISO
Dieldrin affects the expression of NRADD mRNA
CTD
PMID:22546817
NCBI chr 9:110,450,203...110,453,461
Ensembl chr 9:110,450,203...110,453,520
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Nsmaf
neutral sphingomyelinase (N-SMase) activation associated factor
affects expression
ISO
Dieldrin affects the expression of NSMAF mRNA
CTD
PMID:22546817
NCBI chr 4:6,396,207...6,454,840
Ensembl chr 4:6,396,207...6,454,271
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Nt5dc2
5'-nucleotidase domain containing 2
increases expression
ISO
Dieldrin results in increased expression of NT5DC2 mRNA
CTD
PMID:23153324
NCBI chr14:30,853,046...30,861,081
Ensembl chr14:30,853,010...30,861,081
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Ntf5
neurotrophin 5
increases expression
ISO
Dieldrin results in increased expression of NTF4 mRNA
CTD
PMID:19130878
NCBI chr 7:45,063,119...45,066,603
Ensembl chr 7:45,063,119...45,066,603
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Ntn1
netrin 1
affects expression
ISO
Dieldrin affects the expression of NTN1 mRNA
CTD
PMID:22546817
NCBI chr11:68,100,190...68,277,652
Ensembl chr11:68,100,190...68,291,649
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Ntrk1
neurotrophic tyrosine kinase, receptor, type 1
increases expression multiple interactions
ISO
Dieldrin results in increased expression of NTRK1 mRNA [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK1 mRNA
CTD
PMID:19130878 PMID:28263720
NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469
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Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
affects expression multiple interactions
ISO
Dieldrin affects the expression of NTRK2 mRNA [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK2 mRNA
CTD
PMID:19130878 PMID:28263720
NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
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Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
decreases expression
ISO
Dieldrin results in decreased expression of NTRK3 mRNA
CTD
PMID:19130878
NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760
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Nts
neurotensin
increases expression
ISO
Dieldrin results in increased expression of NTS mRNA
CTD
PMID:20682304
NCBI chr10:102,317,617...102,326,294
Ensembl chr10:102,317,617...102,326,347
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Nuf2
NUF2, NDC80 kinetochore complex component
affects expression
ISO
Dieldrin affects the expression of NUF2 mRNA
CTD
PMID:22546817
NCBI chr 1:169,325,503...169,359,033
Ensembl chr 1:169,325,503...169,359,033
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Oasl1
2'-5' oligoadenylate synthetase-like 1
decreases expression
ISO
Dieldrin results in decreased expression of OASL mRNA
CTD
PMID:34051100
NCBI chr 5:115,061,236...115,075,970
Ensembl chr 5:115,061,299...115,075,974
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Opa1
OPA1, mitochondrial dynamin like GTPase
affects expression
ISO
Dieldrin affects the expression of OPA1 mRNA
CTD
PMID:22546817
NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
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Otx2
orthodenticle homeobox 2
multiple interactions
ISO
Dieldrin inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of OTX2 mRNA]
CTD
PMID:32949729
NCBI chr14:48,894,238...48,905,101
Ensembl chr14:48,895,134...48,911,276
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P2rx4
purinergic receptor P2X, ligand-gated ion channel 4
decreases expression
ISO
Dieldrin results in decreased expression of P2RX4 mRNA
CTD
PMID:23153324
NCBI chr 5:122,845,581...122,867,802
Ensembl chr 5:122,845,607...122,867,801
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Pard6a
par-6 family cell polarity regulator alpha
affects expression
ISO
Dieldrin affects the expression of PARD6A mRNA
CTD
PMID:22546817
NCBI chr 8:106,427,780...106,430,126
Ensembl chr 8:106,427,780...106,430,128
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Parm1
prostate androgen-regulated mucin-like protein 1
affects expression
ISO
Dieldrin affects the expression of PARM1 mRNA
CTD
PMID:22546817
NCBI chr 5:91,665,559...91,771,870
Ensembl chr 5:91,665,474...91,774,753
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Parp1
poly (ADP-ribose) polymerase family, member 1
increases cleavage multiple interactions
ISO
Dieldrin results in increased cleavage of PARP1 protein benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dieldrin results in increased cleavage of PARP1 protein]
CTD
PMID:15183012
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
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Pax6
paired box 6
multiple interactions
ISO
Dieldrin inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of PAX6 mRNA]
CTD
PMID:32949729
NCBI chr 2:105,499,241...105,528,755
Ensembl chr 2:105,499,245...105,527,709
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Pbk
PDZ binding kinase
increases expression
ISO
Dieldrin results in increased expression of PBK mRNA
CTD
PMID:23153324
NCBI chr14:66,043,337...66,055,271
Ensembl chr14:66,043,286...66,055,271
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Pcna
proliferating cell nuclear antigen
increases expression
ISO
Dieldrin results in increased expression of PCNA mRNA
CTD
PMID:23153324
NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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Pdcd2
programmed cell death 2
affects expression
ISO
Dieldrin affects the expression of PDCD2 mRNA
CTD
PMID:22546817
NCBI chr17:15,739,472...15,747,560
Ensembl chr17:15,739,470...15,747,563
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Pdcd6
programmed cell death 6
affects expression
ISO
Dieldrin affects the expression of PDCD6 mRNA
CTD
PMID:22546817
NCBI chr13:74,451,240...74,465,445
Ensembl chr13:74,451,628...74,465,699
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Pdgfa
platelet derived growth factor, alpha
affects expression
ISO
Dieldrin affects the expression of PDGFA mRNA
CTD
PMID:22546817
NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
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Pdgfra
platelet derived growth factor receptor, alpha polypeptide
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRA mRNA
CTD
PMID:19422813
NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876
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Pdgfrb
platelet derived growth factor receptor, beta polypeptide
multiple interactions
ISO
[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRB mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of PDGFRB mRNA
CTD
PMID:19422813 PMID:28263720
NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
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Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
decreases expression
ISO
Dieldrin results in decreased expression of PDK1 mRNA
CTD
PMID:23153324
NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202
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Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
decreases expression
ISO
Dieldrin results in decreased expression of PDK4 mRNA
CTD
PMID:23153324
NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
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Penk
preproenkephalin
decreases expression
ISO
Dieldrin results in decreased expression of PENK mRNA
CTD
PMID:20682304
NCBI chr 4:4,133,536...4,138,815
Ensembl chr 4:4,133,531...4,138,819
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Pgf
placental growth factor
affects expression
ISO
Dieldrin affects the expression of PGF mRNA
CTD
PMID:22546817
NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564
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Pgr
progesterone receptor
increases expression multiple interactions
ISO
Dieldrin results in increased expression of PGR mRNA Dieldrin inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]
CTD
PMID:10774817 PMID:26022396
NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
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Phlda1
pleckstrin homology like domain, family A, member 1
affects expression increases expression
ISO
Dieldrin affects the expression of PHLDA1 mRNA Dieldrin results in increased expression of PHLDA1 mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr10:111,342,147...111,344,510
Ensembl chr10:111,342,147...111,344,506
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Pidd1
p53 induced death domain protein 1
affects expression
ISO
Dieldrin affects the expression of PIDD1 mRNA
CTD
PMID:22546817
NCBI chr 7:141,018,026...141,027,477
Ensembl chr 7:141,018,026...141,023,938
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Plagl2
pleiomorphic adenoma gene-like 2
affects expression
ISO
Dieldrin affects the expression of PLAGL2 mRNA
CTD
PMID:22546817
NCBI chr 2:153,069,689...153,083,278
Ensembl chr 2:153,069,679...153,083,346
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Plcb1
phospholipase C, beta 1
affects expression
ISO
Dieldrin affects the expression of PLCB1 mRNA
CTD
PMID:22546817
NCBI chr 2:134,628,084...135,317,178
Ensembl chr 2:134,627,987...135,317,178
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Plekhf1
pleckstrin homology domain containing, family F (with FYVE domain) member 1
affects expression
ISO
Dieldrin affects the expression of PLEKHF1 mRNA
CTD
PMID:22546817
NCBI chr 7:37,920,078...37,927,418
Ensembl chr 7:37,916,396...37,927,440
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Plk1
polo like kinase 1
affects expression
ISO
Dieldrin affects the expression of PLK1 mRNA
CTD
PMID:22546817
NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096
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Plk2
polo like kinase 2
affects expression
ISO
Dieldrin affects the expression of PLK2 mRNA
CTD
PMID:22546817
NCBI chr13:110,531,578...110,537,378
Ensembl chr13:110,531,580...110,537,378
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Plk4
polo like kinase 4
affects expression
ISO
Dieldrin affects the expression of PLK4 mRNA
CTD
PMID:22546817
NCBI chr 3:40,754,463...40,771,318
Ensembl chr 3:40,754,454...40,771,318
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Plpp3
phospholipid phosphatase 3
decreases expression
ISO
Dieldrin results in decreased expression of PLPP3 mRNA
CTD
PMID:23153324
NCBI chr 4:105,014,544...105,089,964
Ensembl chr 4:105,014,544...105,089,961
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Plxnd1
plexin D1
multiple interactions
ISO
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of PLXND1 mRNA
CTD
PMID:28263720
NCBI chr 6:115,931,772...115,972,300
Ensembl chr 6:115,931,772...115,971,966
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Pmp22
peripheral myelin protein 22
affects expression
ISO
Dieldrin affects the expression of PMP22 mRNA
CTD
PMID:22546817
NCBI chr11:63,019,808...63,050,373
Ensembl chr11:63,019,808...63,050,373
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Pnpla6
patatin-like phospholipase domain containing 6
decreases expression
ISO
Dieldrin results in decreased expression of PNPLA6 mRNA
CTD
PMID:31068361
NCBI chr 8:3,565,341...3,594,267
Ensembl chr 8:3,565,384...3,594,267
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Pnrc1
proline-rich nuclear receptor coactivator 1
increases expression
ISO
Dieldrin results in increased expression of PNRC1 mRNA
CTD
PMID:31068361
NCBI chr 4:33,245,423...33,248,787
Ensembl chr 4:33,245,423...33,290,163
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Pon1
paraoxonase 1
multiple interactions
ISO
[Dieldrin co-treated with NR1I2 protein] results in increased expression of PON1 mRNA; [Dieldrin co-treated with RXRA protein co-treated with NR1I2 protein] results in increased expression of PON1 mRNA; [Dieldrin co-treated with RXRA protein] results in increased expression of PON1 mRNA
CTD
PMID:24615737
NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
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Pou5f1
POU domain, class 5, transcription factor 1
multiple interactions
ISO
Dieldrin promotes the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in decreased expression of POU5F1 mRNA]
CTD
PMID:32949729
NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669
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Ppp1r10
protein phosphatase 1, regulatory subunit 10
increases expression
ISO
Dieldrin results in increased expression of PPP1R10 mRNA
CTD
PMID:31068361
NCBI chr17:36,227,404...36,243,175
Ensembl chr17:36,227,326...36,243,175
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Ppp1r13b
protein phosphatase 1, regulatory subunit 13B
affects expression
ISO
Dieldrin affects the expression of PPP1R13B mRNA
CTD
PMID:22546817
NCBI chr12:111,794,892...111,874,549
Ensembl chr12:111,794,891...111,874,544
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
Dieldrin results in increased expression of PPP1R15A mRNA
CTD
PMID:31068361
NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
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Prkcd
protein kinase C, delta
multiple interactions increases activity affects expression
ISO
BCL2 protein inhibits the reaction [Dieldrin results in increased activity of PRKCD protein] benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dieldrin results in increased cleavage of and results in increased activity of PRKCD protein]; Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]; Dieldrin results in increased cleavage of and results in increased activity of PRKCD protein; Dieldrin results in increased phosphorylation of and results in increased cleavage of PRKCD protein; FYN protein promotes the reaction [Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]]; FYN protein promotes the reaction [Dieldrin results in increased phosphorylation of PRKCD protein] Dieldrin affects the expression of PRKCD mRNA
CTD
PMID:12831855 PMID:15033812 PMID:21801747 PMID:22546817
NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
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Prkn
parkin RBR E3 ubiquitin protein ligase
increases response to substance
ISO
PARK2 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
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Prl
prolactin
multiple interactions increases secretion
ISO
Nifedipine inhibits the reaction [Dieldrin results in increased secretion of PRL protein]
CTD
PMID:15811834 PMID:17174995
NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
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Prx
periaxin
decreases expression
ISO
Dieldrin results in decreased expression of PRX mRNA
CTD
PMID:31068361
NCBI chr 7:27,198,730...27,219,466
Ensembl chr 7:27,196,813...27,219,639
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Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
affects expression
ISO
Dieldrin affects the expression of PSMD1 mRNA
CTD
PMID:22546817
NCBI chr 1:85,992,341...86,067,017
Ensembl chr 1:85,992,109...86,066,873
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Pten
phosphatase and tensin homolog
increases response to substance
ISO
PTEN gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
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Ptger4
prostaglandin E receptor 4 (subtype EP4)
increases expression
ISO
Dieldrin results in increased expression of PTGER4 mRNA
CTD
PMID:31068361
NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668
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Ptn
pleiotrophin
affects expression
ISO
Dieldrin affects the expression of PTN mRNA
CTD
PMID:22546817
NCBI chr 6:36,691,863...36,787,114
Ensembl chr 6:36,691,864...36,787,155
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Pttg1
pituitary tumor-transforming gene 1
increases expression affects expression
ISO
Dieldrin results in increased expression of PTTG1 mRNA Dieldrin affects the expression of PTTG1 mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr11:43,311,097...43,317,417
Ensembl chr11:43,311,077...43,317,078
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Pxn
paxillin
increases response to substance
ISO
PXN gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 5:115,630,035...115,694,046
Ensembl chr 5:115,644,735...115,694,046
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Pycard
PYD and CARD domain containing
affects expression
ISO
Dieldrin affects the expression of PYCARD mRNA
CTD
PMID:22546817
NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
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Rabep1
rabaptin, RAB GTPase binding effector protein 1
affects expression
ISO
Dieldrin affects the expression of RABEP1 mRNA
CTD
PMID:22546817
NCBI chr11:70,735,553...70,833,931
Ensembl chr11:70,735,604...70,833,931
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Rad1
RAD1 checkpoint DNA exonuclease
affects expression
ISO
Dieldrin affects the expression of RAD1 mRNA
CTD
PMID:22546817
NCBI chr15:10,486,104...10,499,149
Ensembl chr15:10,486,104...10,499,149
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Raf1
v-raf-leukemia viral oncogene 1
multiple interactions
ISO
Dieldrin results in increased phosphorylation of and results in increased activity of RAF1 protein
CTD
PMID:15888667
NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596
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Rap1a
RAS-related protein 1a
affects expression
ISO
Dieldrin affects the expression of RAP1A mRNA
CTD
PMID:22546817
NCBI chr 3:105,634,576...105,708,740
Ensembl chr 3:105,634,583...105,708,652
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Rara
retinoic acid receptor, alpha
affects expression
ISO
Dieldrin affects the expression of RARA mRNA
CTD
PMID:22546817
NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768
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Rarb
retinoic acid receptor, beta
increases expression
ISO
Dieldrin results in increased expression of RARB mRNA
CTD
PMID:15589975
NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924
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Rarg
retinoic acid receptor, gamma
increases expression increases activity
ISO
Dieldrin results in increased expression of RARG mRNA Dieldrin results in increased activity of RARG protein
CTD
PMID:15589975 PMID:30639747
NCBI chr15:102,143,373...102,165,891
Ensembl chr15:102,143,373...102,165,952
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Rb1
RB transcriptional corepressor 1
affects expression
ISO
Dieldrin affects the expression of RB1 mRNA
CTD
PMID:22546817
NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
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Rbl2
RB transcriptional corepressor like 2
affects expression decreases expression
ISO
Dieldrin affects the expression of RBL2 mRNA Dieldrin results in decreased expression of RBL2 mRNA
CTD
PMID:22546817 PMID:23153324
NCBI chr 8:91,796,685...91,850,472
Ensembl chr 8:91,796,685...91,850,472
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Ret
ret proto-oncogene
affects expression multiple interactions
ISO
Dieldrin affects the expression of RET mRNA [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA
CTD
PMID:22546817 PMID:28263720
NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679
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Rfc4
replication factor C (activator 1) 4
increases expression
ISO
Dieldrin results in increased expression of RFC4 mRNA
CTD
PMID:23153324
NCBI chr16:22,932,698...22,946,480
Ensembl chr16:22,932,693...22,946,487
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Rgs2
regulator of G-protein signaling 2
affects expression increases expression
ISO
Dieldrin affects the expression of RGS2 mRNA Dieldrin results in increased expression of RGS2 mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr 1:143,875,076...143,879,887
Ensembl chr 1:143,875,076...143,879,899
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Rigi
RNA sensor RIG-I
decreases expression
ISO
Dieldrin results in decreased expression of RIGI mRNA
CTD
PMID:34051100
NCBI chr 4:40,203,775...40,239,843
Ensembl chr 4:40,203,773...40,239,828
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Ripk2
receptor (TNFRSF)-interacting serine-threonine kinase 2
affects expression
ISO
Dieldrin affects the expression of RIPK2 mRNA
CTD
PMID:22546817
NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647
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Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
decreases expression
ISO
Dieldrin results in decreased expression of RNASEL mRNA
CTD
PMID:34051100
NCBI chr 1:153,625,089...153,644,441
Ensembl chr 1:153,625,172...153,639,967
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Rnd3
Rho family GTPase 3
affects expression
ISO
Dieldrin affects the expression of RND3 mRNA
CTD
PMID:22546817
NCBI chr 2:51,020,451...51,039,123
Ensembl chr 2:51,020,450...51,039,123
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Rnf34
ring finger protein 34
affects expression
ISO
Dieldrin affects the expression of RNF34 mRNA
CTD
PMID:22546817
NCBI chr 5:122,988,270...123,007,008
Ensembl chr 5:122,988,111...123,009,354
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Rnf7
ring finger protein 7
decreases response to substance
ISO
RNF7 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 9:96,352,990...96,360,728
Ensembl chr 9:96,352,990...96,360,728
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Rtn4
reticulon 4
affects expression
ISO
Dieldrin affects the expression of RTN4 mRNA
CTD
PMID:22546817
NCBI chr11:29,642,898...29,694,414
Ensembl chr11:29,642,947...29,694,331
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Rxra
retinoid X receptor alpha
multiple interactions
ISO
[Dieldrin co-treated with RXRA protein co-treated with NR1I2 protein] results in increased expression of PON1 mRNA; [Dieldrin co-treated with RXRA protein] results in increased expression of PON1 mRNA
CTD
PMID:24615737
NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
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S100a6
S100 calcium binding protein A6 (calcyclin)
affects expression
ISO
Dieldrin affects the expression of S100A6 mRNA
CTD
PMID:22546817
NCBI chr 3:90,520,491...90,531,797
Ensembl chr 3:90,520,189...90,531,488
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Sall1
spalt like transcription factor 1
decreases expression
ISO
Dieldrin results in decreased expression of SALL1 mRNA
CTD
PMID:23153324
NCBI chr 8:89,753,867...89,770,790
Ensembl chr 8:89,753,863...89,770,790
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Sart1
squamous cell carcinoma antigen recognized by T cells 1
affects expression
ISO
Dieldrin affects the expression of SART1 mRNA
CTD
PMID:22546817
NCBI chr19:5,427,551...5,438,731
Ensembl chr19:5,427,551...5,438,731
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Sbf1
SET binding factor 1
decreases expression
ISO
Dieldrin results in decreased expression of SBF1 mRNA
CTD
PMID:31068361
NCBI chr15:89,171,138...89,199,514
Ensembl chr15:89,172,439...89,199,514
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Scn2a
sodium channel, voltage-gated, type II, alpha
affects expression
ISO
Dieldrin affects the expression of SCN2A mRNA
CTD
PMID:22546817
NCBI chr 2:65,451,108...65,597,791
Ensembl chr 2:65,451,115...65,597,791
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Septin7
septin 7
affects expression
ISO
Dieldrin affects the expression of SEPTIN7 mRNA
CTD
PMID:22546817
NCBI chr 9:25,163,287...25,219,867
Ensembl chr 9:25,163,735...25,219,867
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Serinc3
serine incorporator 3
affects expression
ISO
Dieldrin affects the expression of SERINC3 mRNA
CTD
PMID:22546817
NCBI chr 2:163,466,577...163,487,767
Ensembl chr 2:163,465,192...163,487,051
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Serpine1
serine (or cysteine) peptidase inhibitor, clade E, member 1
increases expression
ISO
Dieldrin results in increased expression of SERPINE1 mRNA
CTD
PMID:31068361
NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
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Sf1
splicing factor 1
affects expression
ISO
Dieldrin affects the expression of SF1 mRNA
CTD
PMID:22546817
NCBI chr19:6,413,952...6,428,060
Ensembl chr19:6,413,720...6,428,060
G
Sgk1
serum/glucocorticoid regulated kinase 1
affects expression increases expression
ISO
Dieldrin affects the expression of SGK1 mRNA Dieldrin results in increased expression of SGK1 mRNA
CTD
PMID:22546817 PMID:31068361
NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802
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Sgpl1
sphingosine phosphate lyase 1
affects expression
ISO
Dieldrin affects the expression of SGPL1 mRNA
CTD
PMID:22546817
NCBI chr10:60,934,421...60,983,463
Ensembl chr10:60,934,421...60,983,482
G
Sgpp1
sphingosine-1-phosphate phosphatase 1
affects expression
ISO
Dieldrin affects the expression of SGPP1 mRNA
CTD
PMID:22546817
NCBI chr12:75,761,022...75,782,503
Ensembl chr12:75,761,023...75,782,503
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Shbg
sex hormone binding globulin
multiple interactions
ISO
Dieldrin inhibits the reaction [Dihydrotestosterone binds to SHBG protein]
CTD
PMID:9171990
NCBI chr11:69,501,108...69,508,852
Ensembl chr11:69,505,630...69,508,731
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Shld2
shieldin complex subunit 2
decreases expression
ISO
Dieldrin results in decreased expression of SHLD2 mRNA
CTD
PMID:23153324
NCBI chr14:33,958,905...34,032,528
Ensembl chr14:33,958,990...34,032,450
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Sik1
salt inducible kinase 1
increases expression
ISO
Dieldrin results in increased expression of SIK1 mRNA
CTD
PMID:31068361
NCBI chr17:32,063,222...32,074,808
Ensembl chr17:32,063,224...32,074,778
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Sipa1
signal-induced proliferation associated gene 1
affects expression
ISO
Dieldrin affects the expression of SIPA1 mRNA
CTD
PMID:22546817
NCBI chr19:5,701,211...5,713,758
Ensembl chr19:5,701,213...5,713,735
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Sirt2
sirtuin 2
affects expression
ISO
Dieldrin affects the expression of SIRT2 mRNA
CTD
PMID:22546817
NCBI chr 7:28,466,192...28,488,086
Ensembl chr 7:28,466,160...28,488,086
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Slc10a1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
decreases expression
ISO
Dieldrin results in decreased expression of SLC10A1 mRNA
CTD
PMID:23153324 PMID:24464585
NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
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Slc12a4
solute carrier family 12, member 4
affects expression
ISO
Dieldrin affects the expression of SLC12A4 mRNA
CTD
PMID:22546817
NCBI chr 8:106,670,222...106,692,781
Ensembl chr 8:106,670,222...106,692,729
G
Slc13a3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
decreases expression
ISO
Dieldrin results in decreased expression of SLC13A3 mRNA
CTD
PMID:23153324
NCBI chr 2:165,247,215...165,315,117
Ensembl chr 2:165,246,948...165,315,150
G
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
decreases expression
ISO
Dieldrin results in decreased expression of SLC16A1 mRNA
CTD
PMID:23153324
NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778
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Slc16a11
solute carrier family 16 (monocarboxylic acid transporters), member 11
decreases expression
ISO
Dieldrin results in decreased expression of SLC16A11 mRNA
CTD
PMID:23153324
NCBI chr11:70,104,717...70,107,239
Ensembl chr11:70,103,578...70,107,243
G
Slc16a2
solute carrier family 16 (monocarboxylic acid transporters), member 2
decreases expression
ISO
Dieldrin results in decreased expression of SLC16A2 mRNA
CTD
PMID:23153324
NCBI chr X:102,741,020...102,865,594
Ensembl chr X:102,741,020...102,865,589
G
Slc16a4
solute carrier family 16 (monocarboxylic acid transporters), member 4
decreases expression
ISO
Dieldrin results in decreased expression of SLC16A4 mRNA
CTD
PMID:23153324
NCBI chr 3:107,198,543...107,219,437
Ensembl chr 3:107,198,546...107,219,431
G
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
decreases expression
ISO
Dieldrin results in decreased expression of SLC16A7 mRNA
CTD
PMID:23153324
NCBI chr10:125,055,139...125,225,455
Ensembl chr10:125,055,139...125,225,334
G
Slc17a2
solute carrier family 17 (sodium phosphate), member 2
decreases expression
ISO
Dieldrin results in decreased expression of SLC17A2 mRNA
CTD
PMID:23153324
NCBI chr13:23,990,924...24,009,174
Ensembl chr13:23,990,976...24,009,163
G
Slc17a3
solute carrier family 17 (sodium phosphate), member 3
decreases expression
ISO
Dieldrin results in decreased expression of SLC17A3 mRNA
CTD
PMID:23153324
NCBI chr13:24,020,905...24,044,701
Ensembl chr13:24,023,417...24,044,699
G
Slc17a5
solute carrier family 17 (anion/sugar transporter), member 5
decreases expression
ISO
Dieldrin results in decreased expression of SLC17A5 mRNA
CTD
PMID:23153324
NCBI chr 9:78,443,769...78,495,346
Ensembl chr 9:78,443,770...78,495,323
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Slc18a1
solute carrier family 18 (vesicular monoamine), member 1
decreases expression
ISO
Dieldrin results in decreased expression of SLC18A1 mRNA
CTD
PMID:18812211 PMID:18835401
NCBI chr 8:69,490,360...69,547,951
Ensembl chr 8:69,490,363...69,541,887
G
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
increases expression
EXP
Dieldrin results in increased expression of SLC18A2 mRNA; Dieldrin results in increased expression of SLC18A2 protein
CTD
PMID:16809432
NCBI chr19:59,249,310...59,284,444
Ensembl chr19:59,249,328...59,284,444
G
Slc18a3
solute carrier family 18 (vesicular monoamine), member 3
affects expression
ISO
Dieldrin affects the expression of SLC18A3 mRNA
CTD
PMID:18812211
NCBI chr14:32,184,394...32,186,807
Ensembl chr14:32,184,395...32,186,807
G
Slc19a2
solute carrier family 19 (thiamine transporter), member 2
decreases expression
ISO
Dieldrin results in decreased expression of SLC19A2 mRNA
CTD
PMID:23153324
NCBI chr 1:164,076,615...164,092,954
Ensembl chr 1:164,076,615...164,092,954
G
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
multiple interactions
EXP
[Dieldrin co-treated with NGF protein] results in increased expression of SLC1A5 mRNA
CTD
PMID:20600679
NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199
G
Slc22a1
solute carrier family 22 (organic cation transporter), member 1
decreases activity
ISO
Dieldrin results in decreased activity of SLC22A1 protein
CTD
PMID:24464585
NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
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Slc22a23
solute carrier family 22, member 23
decreases expression
ISO
Dieldrin results in decreased expression of SLC22A23 mRNA
CTD
PMID:23153324
NCBI chr13:34,363,141...34,530,666
Ensembl chr13:34,363,141...34,529,165
G
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
decreases expression
ISO
Dieldrin results in decreased expression of SLC29A1 mRNA
CTD
PMID:23153324
NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532
G
Slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
decreases expression
ISO
Dieldrin results in decreased expression of SLC2A2 mRNA
CTD
PMID:23153324
NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
G
Slc31a2
solute carrier family 31, member 2
decreases expression
ISO
Dieldrin results in decreased expression of SLC31A2 mRNA
CTD
PMID:23153324
NCBI chr 4:62,198,630...62,216,649
Ensembl chr 4:62,180,799...62,216,648
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Slc34a2
solute carrier family 34 (sodium phosphate), member 2
decreases expression
ISO
Dieldrin results in decreased expression of SLC34A2 mRNA
CTD
PMID:23153324
NCBI chr 5:53,206,695...53,229,006
Ensembl chr 5:53,195,423...53,229,006
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Slc38a1
solute carrier family 38, member 1
increases expression
ISO
Dieldrin results in increased expression of SLC38A1 mRNA
CTD
PMID:23153324
NCBI chr15:96,469,299...96,541,396
Ensembl chr15:96,469,299...96,540,794
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Slc5a6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
decreases expression
ISO
Dieldrin results in decreased expression of SLC5A6 mRNA
CTD
PMID:23153324
NCBI chr 5:31,193,380...31,206,268
Ensembl chr 5:31,193,380...31,206,268
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Slc6a12
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
decreases expression
ISO
Dieldrin results in decreased expression of SLC6A12 mRNA
CTD
PMID:23153324
NCBI chr 6:121,319,533...121,342,732
Ensembl chr 6:121,320,035...121,342,734
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Slc6a2
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
affects expression
ISO
Dieldrin affects the expression of SLC6A2 mRNA
CTD
PMID:18812211
NCBI chr 8:93,687,100...93,728,295
Ensembl chr 8:93,686,707...93,728,295
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Slc6a3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
decreases expression increases expression multiple interactions
EXP ISO
Dieldrin results in decreased expression of SLC6A3 protein Dieldrin results in increased expression of SLC6A3 mRNA; Dieldrin results in increased expression of SLC6A3 protein Dieldrin inhibits the reaction [SLC6A3 protein affects the export of Dopamine]
CTD
PMID:11719704 PMID:16809432 PMID:17291500 PMID:18812211 PMID:19479021
NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791
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Slc6a4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
decreases expression
ISO
Dieldrin results in decreased expression of SLC6A4 mRNA
CTD
PMID:18835401
NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166
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Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
increases expression
ISO
Dieldrin results in increased expression of SLC6A8 mRNA
CTD
PMID:18812211
NCBI chr X:72,716,739...72,726,108
Ensembl chr X:72,716,756...72,726,108
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Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
multiple interactions
EXP
[Dieldrin co-treated with NGF protein] results in increased expression of SLC7A11 mRNA
CTD
PMID:20600679
NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
G
Slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
decreases expression
ISO
Dieldrin results in decreased expression of SLC7A2 mRNA
CTD
PMID:23153324
NCBI chr 8:41,315,404...41,375,107
Ensembl chr 8:41,315,433...41,375,345
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Smap1
small ArfGAP 1
increases expression
ISO
Dieldrin results in increased expression of SMAP1 mRNA
CTD
PMID:31068361
NCBI chr 1:23,883,925...23,961,462
Ensembl chr 1:23,883,927...23,961,398
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Smpd3
sphingomyelin phosphodiesterase 3, neutral
affects expression
ISO
Dieldrin affects the expression of SMPD3 mRNA
CTD
PMID:22546817
NCBI chr 8:106,979,180...107,064,597
Ensembl chr 8:106,979,180...107,064,620
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Snca
synuclein, alpha
multiple interactions increases expression
EXP ISO
Dieldrin promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA protein] Dieldrin results in increased expression of SNCA protein SNCA protein promotes the reaction [Dieldrin results in increased expression of CASP3 protein]
CTD
PMID:15987830 PMID:16809432 PMID:17291500
NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839
G
Snora73b
small nucleolar RNA, H/ACA box 73b
increases expression
ISO
Dieldrin results in increased expression of SNORA73B mRNA
CTD
PMID:31068361
NCBI chr 4:132,079,633...132,079,837
Ensembl chr 4:132,079,633...132,079,837
G
Sod1
superoxide dismutase 1, soluble
decreases expression affects expression
ISO
Dieldrin results in decreased expression of SOD1 mRNA Dieldrin affects the expression of SOD1 mRNA
CTD
PMID:19440498 PMID:22546817
NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
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Sod2
superoxide dismutase 2, mitochondrial
increases expression
ISO
Dieldrin results in increased expression of SOD2 mRNA
CTD
PMID:19440498
NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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Son
Son DNA binding protein
affects expression
ISO
Dieldrin affects the expression of SON mRNA
CTD
PMID:22546817
NCBI chr16:91,444,712...91,476,080
Ensembl chr16:91,444,394...91,476,109
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Sp1
trans-acting transcription factor 1
decreases response to substance
ISO
SP1 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839
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Spag5
sperm associated antigen 5
affects expression
ISO
Dieldrin affects the expression of SPAG5 mRNA
CTD
PMID:22546817
NCBI chr11:78,192,412...78,213,283
Ensembl chr11:78,192,355...78,213,283
G
Spata3
spermatogenesis associated 3
affects expression
ISO
Dieldrin affects the expression of SPATA3 mRNA
CTD
PMID:22546817
NCBI chr 1:85,945,728...85,957,683
Ensembl chr 1:85,944,538...85,957,680
G
Sqstm1
sequestosome 1
affects expression
ISO
Dieldrin affects the expression of SQSTM1 mRNA
CTD
PMID:22546817
NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
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Src
Rous sarcoma oncogene
affects expression
ISO
Dieldrin affects the expression of SRC mRNA
CTD
PMID:22546817
NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
G
Srsf5
serine and arginine-rich splicing factor 5
affects expression
ISO
Dieldrin affects the expression of SRSF5 mRNA
CTD
PMID:22546817
NCBI chr12:80,992,308...80,997,277
Ensembl chr12:80,992,278...80,997,281
G
Sstr3
somatostatin receptor 3
increases expression
ISO
Dieldrin results in increased expression of SSTR3 mRNA
CTD
PMID:20682304
NCBI chr15:78,421,214...78,433,565
Ensembl chr15:78,421,208...78,428,885
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Stat2
signal transducer and activator of transcription 2
decreases expression
ISO
Dieldrin results in decreased expression of STAT2 mRNA
CTD
PMID:34051100
NCBI chr10:128,106,367...128,128,722
Ensembl chr10:128,106,428...128,128,718
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Steap3
STEAP family member 3
affects expression
ISO
Dieldrin affects the expression of STEAP3 mRNA
CTD
PMID:22546817
NCBI chr 1:120,154,137...120,198,810
Ensembl chr 1:120,118,487...120,200,435
G
Stk11
serine/threonine kinase 11
decreases response to substance
ISO
STK11 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516
G
Stk17b
serine/threonine kinase 17b (apoptosis-inducing)
affects expression
ISO
Dieldrin affects the expression of STK17B mRNA
CTD
PMID:22546817
NCBI chr 1:53,794,671...53,824,374
Ensembl chr 1:53,794,665...53,824,383
G
Sugt1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
affects expression
ISO
Dieldrin affects the expression of SUGT1 mRNA
CTD
PMID:22546817
NCBI chr14:79,825,100...79,868,237
Ensembl chr14:79,825,131...79,872,636
G
Syvn1
synovial apoptosis inhibitor 1, synoviolin
affects expression
ISO
Dieldrin affects the expression of SYVN1 mRNA
CTD
PMID:22546817
NCBI chr19:6,096,586...6,103,748
Ensembl chr19:6,096,606...6,103,742
G
Tac1
tachykinin 1
increases expression
ISO
Dieldrin results in increased expression of TAC1 mRNA
CTD
PMID:20682304
NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
G
Tac4
tachykinin 4
increases expression
ISO
Dieldrin results in increased expression of TAC4 mRNA
CTD
PMID:20682304
NCBI chr11:95,152,355...95,160,091
Ensembl chr11:95,152,355...95,160,091
G
Tagap
T cell activation Rho GTPase activating protein
increases expression
ISO
Dieldrin results in increased expression of TAGAP mRNA
CTD
PMID:31068361
NCBI chr17:8,144,832...8,153,729
Ensembl chr17:8,144,832...8,153,729
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Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
decreases expression
ISO
Dieldrin results in decreased expression of TAP1 mRNA
CTD
PMID:31068361
NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199
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Tcf19
transcription factor 19
affects expression
ISO
Dieldrin affects the expression of TCF19 mRNA
CTD
PMID:22546817
NCBI chr17:35,823,627...35,827,730
Ensembl chr17:35,823,631...35,827,721
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Tcf7
transcription factor 7, T cell specific
affects expression
ISO
Dieldrin affects the expression of TCF7 mRNA
CTD
PMID:22546817
NCBI chr11:52,137,347...52,174,211
Ensembl chr11:52,143,198...52,174,158
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Tfdp2
transcription factor Dp 2
affects expression
ISO
Dieldrin affects the expression of TFDP2 mRNA
CTD
PMID:22546817
NCBI chr 9:96,078,348...96,205,699
Ensembl chr 9:96,078,328...96,205,699
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Tgfb1
transforming growth factor, beta 1
multiple interactions decreases activity affects expression
ISO
Dieldrin inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein] Dieldrin results in decreased activity of TGFB1 protein Dieldrin affects the expression of TGFB1 mRNA
CTD
PMID:10200566 PMID:11238185 PMID:22546817
NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
G
Tgfb3
transforming growth factor, beta 3
affects expression
ISO
Dieldrin affects the expression of TGFB3 mRNA
CTD
PMID:22546817
NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815
G
Tgm2
transglutaminase 2, C polypeptide
affects expression
ISO
Dieldrin affects the expression of TGM2 mRNA
CTD
PMID:22546817
NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356
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Th
tyrosine hydroxylase
increases expression
ISO
Dieldrin results in increased expression of TH mRNA
CTD
PMID:18812211
NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
G
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
affects expression
ISO
Dieldrin affects the expression of TIAL1 mRNA
CTD
PMID:22546817
NCBI chr 7:128,041,496...128,063,450
Ensembl chr 7:128,041,501...128,063,441
G
Timp3
tissue inhibitor of metalloproteinase 3
affects expression
ISO
Dieldrin affects the expression of TIMP3 mRNA
CTD
PMID:22546817
NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370
G
Tjp1
tight junction protein 1
decreases expression
ISO
Dieldrin results in decreased expression of TJP1 protein
CTD
PMID:15082077
NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
G
Tle1
transducin-like enhancer of split 1
decreases expression
ISO
Dieldrin results in decreased expression of TLE1 mRNA
CTD
PMID:23153324
NCBI chr 4:72,028,182...72,124,575
Ensembl chr 4:72,036,042...72,119,130
G
Tmbim6
transmembrane BAX inhibitor motif containing 6
affects expression
ISO
Dieldrin affects the expression of TMBIM6 mRNA
CTD
PMID:22546817
NCBI chr15:99,290,828...99,307,930
Ensembl chr15:99,290,763...99,307,930
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Tnf
tumor necrosis factor
increases expression multiple interactions
ISO
Dieldrin results in increased expression of TNF mRNA; Dieldrin results in increased expression of TNF protein 1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Dieldrin results in increased expression of TNF mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dieldrin results in increased expression of TNF mRNA]; Tacrolimus inhibits the reaction [Dieldrin results in increased expression of TNF mRNA]; Wortmannin inhibits the reaction [Dieldrin results in increased expression of TNF mRNA]
CTD
PMID:13129777 PMID:15135310 PMID:31068361
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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Tnfaip3
tumor necrosis factor, alpha-induced protein 3
increases expression
ISO
Dieldrin results in increased expression of TNFAIP3 mRNA
CTD
PMID:31068361
NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
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Tnfaip8
tumor necrosis factor, alpha-induced protein 8
affects expression
ISO
Dieldrin affects the expression of TNFAIP8 mRNA
CTD
PMID:22546817
NCBI chr18:50,112,494...50,226,296
Ensembl chr18:50,112,494...50,240,240
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Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
affects expression
ISO
Dieldrin affects the expression of TNFRSF1A mRNA
CTD
PMID:22546817
NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
G
Tnfsf9
tumor necrosis factor (ligand) superfamily, member 9
increases expression
ISO
Dieldrin results in increased expression of TNFSF9 mRNA
CTD
PMID:31068361
NCBI chr17:57,412,113...57,414,757
Ensembl chr17:57,412,325...57,414,757
G
Tph1
tryptophan hydroxylase 1
increases expression
ISO
Dieldrin results in increased expression of TPH1 mRNA
CTD
PMID:18835401
NCBI chr 7:46,294,065...46,321,961
Ensembl chr 7:46,294,065...46,321,961
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Tradd
TNFRSF1A-associated via death domain
affects expression
ISO
Dieldrin affects the expression of TRADD mRNA
CTD
PMID:22546817
NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241
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Trib3
tribbles pseudokinase 3
affects expression
ISO
Dieldrin affects the expression of TRIB3 mRNA
CTD
PMID:22546817
NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
G
Trip13
thyroid hormone receptor interactor 13
increases expression
ISO
Dieldrin results in increased expression of TRIP13 mRNA
CTD
PMID:23153324
NCBI chr13:74,060,577...74,085,855
Ensembl chr13:74,059,466...74,085,903
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Trp53
transformation related protein 53
affects expression increases activity decreases response to substance
ISO EXP
Dieldrin affects the expression of TP53 mRNA Dieldrin results in increased activity of TRP53 protein TP53 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:22546817 PMID:22634143 PMID:32421776
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
G
Tsc1
TSC complex subunit 1
affects expression increases response to substance
ISO
Dieldrin affects the expression of TSC1 mRNA TSC1 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:22546817 PMID:32421776
NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179
G
Tsc2
TSC complex subunit 2
affects expression increases response to substance
ISO
Dieldrin affects the expression of TSC2 mRNA TSC2 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:22546817 PMID:32421776
NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604
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Tsc22d3
TSC22 domain family, member 3
increases expression
ISO
Dieldrin results in increased expression of TSC22D3 mRNA
CTD
PMID:31068361
NCBI chr X:139,440,277...139,501,257
Ensembl chr X:139,440,277...139,501,408
G
Ttk
Ttk protein kinase
affects expression
ISO
Dieldrin affects the expression of TTK mRNA
CTD
PMID:22546817
NCBI chr 9:83,716,704...83,754,442
Ensembl chr 9:83,716,742...83,754,442
G
Ttpa
tocopherol (alpha) transfer protein
decreases expression
ISO
Dieldrin results in decreased expression of TTPA mRNA
CTD
PMID:23153324
NCBI chr 4:20,007,889...20,030,823
Ensembl chr 4:20,007,938...20,030,785
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Tube1
tubulin, epsilon 1
affects expression
ISO
Dieldrin affects the expression of TUBE1 mRNA
CTD
PMID:22546817
NCBI chr10:39,009,946...39,035,863
Ensembl chr10:39,009,972...39,028,538
G
Txnip
thioredoxin interacting protein
decreases expression
ISO
Dieldrin results in decreased expression of TXNIP mRNA
CTD
PMID:31068361
NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
G
Uba6
ubiquitin-like modifier activating enzyme 6
increases response to substance
ISO
UBA6 gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 5:86,258,579...86,320,602
Ensembl chr 5:86,257,146...86,320,662
G
Uba7
ubiquitin-like modifier activating enzyme 7
decreases expression
ISO
Dieldrin results in decreased expression of UBA7 mRNA
CTD
PMID:34051100
NCBI chr 9:107,852,766...107,861,255
Ensembl chr 9:107,852,704...107,861,259
G
Ube2c
ubiquitin-conjugating enzyme E2C
affects expression
ISO
Dieldrin affects the expression of UBE2C mRNA
CTD
PMID:22546817
NCBI chr 2:164,611,849...164,614,822
Ensembl chr 2:164,611,818...164,620,742
G
Ube2k
ubiquitin-conjugating enzyme E2K
increases response to substance
ISO
UBE2K gene mutant form results in increased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 5:65,694,588...65,756,332
Ensembl chr 5:65,694,576...65,756,331
G
Ube2l6
ubiquitin-conjugating enzyme E2L 6
decreases expression
ISO
Dieldrin results in decreased expression of UBE2L6 mRNA
CTD
PMID:34051100
NCBI chr 2:84,629,172...84,640,347
Ensembl chr 2:84,629,172...84,640,679
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Ube2n
ubiquitin-conjugating enzyme E2N
decreases response to substance decreases expression
ISO
UBE2N gene mutant form results in decreased susceptibility to Dieldrin Dieldrin results in decreased expression of UBE2N mRNA
CTD
PMID:32421776 PMID:34051100
NCBI chr10:95,351,024...95,381,520
Ensembl chr10:95,351,007...95,381,519
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Ube2r2
ubiquitin-conjugating enzyme E2R 2
decreases response to substance
ISO
UBE2R2 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 4:41,136,021...41,193,370
Ensembl chr 4:41,135,743...41,193,380
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Unc5b
unc-5 netrin receptor B
affects expression
ISO
Dieldrin affects the expression of UNC5B mRNA
CTD
PMID:22546817
NCBI chr10:60,598,373...60,667,360
Ensembl chr10:60,598,372...60,667,360
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Uqcrh
ubiquinol-cytochrome c reductase hinge protein
decreases expression
ISO
Dieldrin results in decreased expression of UQCRH mRNA
CTD
PMID:23153324
NCBI chr 4:115,924,162...115,932,267
Ensembl chr 4:115,924,162...115,932,268
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Usp18
ubiquitin specific peptidase 18
decreases expression
ISO
Dieldrin results in decreased expression of USP18 mRNA
CTD
PMID:34051100
NCBI chr 6:121,222,865...121,247,876
Ensembl chr 6:121,222,865...121,247,876
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Usp28
ubiquitin specific peptidase 28
decreases response to substance
ISO
USP28 gene mutant form results in decreased susceptibility to Dieldrin
CTD
PMID:32421776
NCBI chr 9:48,896,577...48,953,817
Ensembl chr 9:48,896,675...48,953,817
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Vegfa
vascular endothelial growth factor A
increases secretion multiple interactions
ISO
Dieldrin results in increased secretion of VEGFA protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]; fulvestrant inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]; wortmannin inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]
CTD
PMID:18252963
NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
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Vegfb
vascular endothelial growth factor B
affects expression
ISO
Dieldrin affects the expression of VEGFB mRNA
CTD
PMID:22546817
NCBI chr19:6,959,840...6,965,019
Ensembl chr19:6,959,841...6,965,019
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Vegfc
vascular endothelial growth factor C
affects expression
ISO
Dieldrin affects the expression of VEGFC mRNA
CTD
PMID:22546817
NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
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Vhl
von Hippel-Lindau tumor suppressor
affects expression
ISO
Dieldrin affects the expression of VHL mRNA
CTD
PMID:22546817
NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594
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Vipr2
vasoactive intestinal peptide receptor 2
increases expression
ISO
Dieldrin results in increased expression of VIPR2 mRNA
CTD
PMID:20682304
NCBI chr12:116,041,040...116,117,842
Ensembl chr12:116,041,346...116,109,881
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Vmp1
vacuole membrane protein 1
increases expression
ISO
Dieldrin results in increased expression of VMP1 mRNA
CTD
PMID:31068361
NCBI chr11:86,474,684...86,574,662
Ensembl chr11:86,474,691...86,574,662
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Vwa5a
von Willebrand factor A domain containing 5A
affects expression
ISO
Dieldrin affects the expression of VWA5A mRNA
CTD
PMID:22546817
NCBI chr 9:38,629,564...38,654,633
Ensembl chr 9:38,629,564...38,654,633
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Wee1
WEE 1 homolog 1 (S. pombe)
affects expression
ISO
Dieldrin affects the expression of WEE1 mRNA
CTD
PMID:22546817
NCBI chr 7:109,721,266...109,742,506
Ensembl chr 7:109,721,253...109,742,493
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Wnt2
wingless-type MMTV integration site family, member 2
decreases expression
ISO
Dieldrin results in decreased expression of WNT2 mRNA
CTD
PMID:19130878
NCBI chr 6:17,988,939...18,032,771
Ensembl chr 6:17,988,939...18,030,584
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Wnt2b
wingless-type MMTV integration site family, member 2B
decreases expression
ISO
Dieldrin results in decreased expression of WNT2B mRNA
CTD
PMID:19130878
NCBI chr 3:104,852,121...104,869,025
Ensembl chr 3:104,852,588...104,869,237
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Wnt3a
wingless-type MMTV integration site family, member 3A
affects expression
ISO
Dieldrin affects the expression of WNT3A mRNA
CTD
PMID:19130878
NCBI chr11:59,138,859...59,181,579
Ensembl chr11:59,138,859...59,181,578
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Wnt4
wingless-type MMTV integration site family, member 4
affects expression
ISO
Dieldrin affects the expression of WNT4 mRNA
CTD
PMID:19130878
NCBI chr 4:137,004,946...137,026,812
Ensembl chr 4:137,004,800...137,027,037
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Wnt5a
wingless-type MMTV integration site family, member 5A
decreases expression
ISO
Dieldrin results in decreased expression of WNT5A mRNA
CTD
PMID:19130878
NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405
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Wnt6
wingless-type MMTV integration site family, member 6
increases expression
ISO
Dieldrin results in increased expression of WNT6 mRNA
CTD
PMID:19130878
NCBI chr 1:74,793,499...74,824,481
Ensembl chr 1:74,811,051...74,824,481
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Wnt7a
wingless-type MMTV integration site family, member 7A
decreases expression
ISO
Dieldrin results in decreased expression of WNT7A mRNA
CTD
PMID:19130878
NCBI chr 6:91,340,963...91,388,335
Ensembl chr 6:91,340,963...91,388,345
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Wnt9a
wingless-type MMTV integration site family, member 9A
affects expression
ISO
Dieldrin affects the expression of WNT9A mRNA
CTD
PMID:19130878
NCBI chr11:59,197,675...59,224,378
Ensembl chr11:59,197,754...59,224,378
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Wnt9b
wingless-type MMTV integration site family, member 9B
affects expression
ISO
Dieldrin affects the expression of WNT9B mRNA
CTD
PMID:19130878
NCBI chr11:103,618,188...103,666,098
Ensembl chr11:103,618,190...103,640,647
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Wt1
WT1 transcription factor
affects expression
ISO
Dieldrin affects the expression of WT1 mRNA
CTD
PMID:22546817
NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961
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Wwox
WW domain-containing oxidoreductase
affects expression
ISO
Dieldrin affects the expression of WWOX mRNA
CTD
PMID:22546817
NCBI chr 8:115,166,377...116,079,451
Ensembl chr 8:115,166,395...116,079,447
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Wwp2
WW domain containing E3 ubiquitin protein ligase 2
affects expression
ISO
Dieldrin affects the expression of WWP2 mRNA
CTD
PMID:22546817
NCBI chr 8:108,162,966...108,285,922
Ensembl chr 8:108,162,997...108,285,227
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Zbtb16
zinc finger and BTB domain containing 16
affects expression
ISO
Dieldrin affects the expression of ZBTB16 mRNA
CTD
PMID:22546817
NCBI chr 9:48,563,097...48,747,525
Ensembl chr 9:48,565,597...48,747,522
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Zbtb17
zinc finger and BTB domain containing 17
affects expression
ISO
Dieldrin affects the expression of ZBTB17 mRNA
CTD
PMID:22546817
NCBI chr 4:141,171,984...141,195,248
Ensembl chr 4:141,171,965...141,195,241
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Zfp36
zinc finger protein 36
increases expression
ISO
Dieldrin results in increased expression of ZFP36 mRNA
CTD
PMID:31068361
NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678
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Zfp36l1
zinc finger protein 36, C3H type-like 1
increases expression
ISO
Dieldrin results in increased expression of ZFP36L1 mRNA
CTD
PMID:31068361
NCBI chr12:80,154,534...80,159,787
Ensembl chr12:80,154,528...80,159,787
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Zmat3
zinc finger matrin type 3
affects expression
ISO
Dieldrin affects the expression of ZMAT3 mRNA
CTD
PMID:22546817
NCBI chr 3:32,388,941...32,419,814
Ensembl chr 3:32,388,941...32,420,163
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