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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Di-n-octyl phthalate
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Accession:CHEBI:34679 term browser browse the term
Definition:A phthalate ester that has formula C24H38O4.
Synonyms:related_synonym: Bis(n-octyl) phthalate;   Dioctyl 1,2-benzenedicarboxylate;   Formula=C24H38O4;   InChI=1S/C24H38O4/c1-3-5-7-9-11-15-19-27-23(25)21-17-13-14-18-22(21)24(26)28-20-16-12-10-8-6-4-2/h13-14,17-18H,3-12,15-16,19-20H2,1-2H3;   InChIKey=MQIUGAXCHLFZKX-UHFFFAOYSA-N;   SMILES=CCCCCCCCOC(=O)c1ccccc1C(=O)OCCCCCCCC
 xref: CAS:117-84-0;   KEGG:C14227
 xref_mesh: MESH:C010715


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Di-n-octyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO di-n-octyl phthalate results in increased expression of ABCC3 mRNA CTD PMID:26519955 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO di-n-octyl phthalate results in increased expression of ACOT1 mRNA CTD PMID:26519955 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Alb albumin decreases expression ISO di-n-octyl phthalate results in decreased expression of ALB protein CTD PMID:29128616 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Ar androgen receptor affects binding
multiple interactions
EXP
ISO
di-n-octyl phthalate binds to AR protein
di-n-octyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
CTD PMID:14565775 PMID:28571686 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bcl2l11 BCL2 like 11 decreases expression ISO di-n-octyl phthalate results in decreased expression of BCL2L11 protein CTD PMID:29128616 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Casp6 caspase 6 decreases expression ISO di-n-octyl phthalate results in decreased expression of CASP6 protein CTD PMID:29128616 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 decreases expression ISO di-n-octyl phthalate results in decreased expression of CASP7 protein CTD PMID:29128616 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 decreases expression ISO di-n-octyl phthalate results in decreased expression of CASP8 protein CTD PMID:29128616 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO di-n-octyl phthalate analog binds to ESR1 protein
di-n-octyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
CTD PMID:15464722 PMID:28571686 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 affects binding
multiple interactions
ISO di-n-octyl phthalate analog binds to ESR2 protein
di-n-octyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]
CTD PMID:15464722 PMID:28571686 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity ISO di-n-octyl phthalate results in increased activity of PPARA protein CTD PMID:24496636 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO di-n-octyl phthalate binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
G Slc5a5 solute carrier family 5 member 5 increases expression ISO
EXP
di-n-octyl phthalate results in increased expression of SLC5A5 mRNA CTD PMID:16257484 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO di-n-octyl phthalate results in increased expression of TGFB1 mRNA CTD PMID:29128616 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Vim vimentin increases expression ISO di-n-octyl phthalate results in increased expression of VIM protein CTD PMID:29128616 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        pharmaceutical 19329
          drug 19329
            hormone receptor modulator 18867
              endocrine disruptor 18655
                phthalate ester 7486
                  Di-n-octyl phthalate 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        aromatic carboxylic acid 11710
                                          benzoic acids 11683
                                            benzenedicarboxylic acid 7762
                                              phthalic acid 7486
                                                phthalate ester 7486
                                                  Di-n-octyl phthalate 15
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