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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:colistimethate sodium
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Accession:CHEBI:34650 term browser browse the term
Definition:A mixture where R = H or Me. Colistin in which each of the primary amino groups is converted to the corresponding aminomethanesulfonic acid sodium salt, commonly by the action of formaldehyde followed by sodium bisulfite. A polymyxin antibiotic derivative, it is used in the treatment of severe infections, particularly of multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii.
Synonyms:related_synonym: Colistin methanesulfonate;   Formula=C57H102N16Na5O28S5R;   SMILES=C(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]1C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)NCC1)[C@@H](C)O)=O)CCNCS([O-])(=O)=O)=O)CCNCS([O-])(=O)=O)=O)CC(C)C)=O)CC(C)C)=O)CCNCS([O-])(=O)=O)=O)=O)CCNCS([O-])(=O)=O)=O)[C@@H](C)O)=O)CCNCS([O-])(=O)=O)=O)CCC[C@@H](C*)C.[Na+].[Na+].[Na+].[Na+].[Na+];   colistimethate;   colistin sulfomethate;   colistin sulfomethate sodium;   pentasodium colistinmethanesulfonate;   sodium colistin methanesulfonate;   sodium colistinemethanesulfonate
 alt_id: CHEBI:597110
 xref: CAS:8068-28-8;   DrugBank:DB01111;   KEGG:C13553;   KEGG:D02049;   PMID:16931410;   PMID:18625681



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Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19810
      biological role 19808
        antimicrobial agent 18202
          peptide antibiotic 1813
            colistimethate sodium 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19722
                        carbon atom 19719
                          organic molecular entity 19719
                            heteroorganic entity 19474
                              organochalcogen compound 19262
                                organooxygen compound 19153
                                  carbon oxoacid 18647
                                    carboxylic acid 18620
                                      carboacyl group 17681
                                        univalent carboacyl group 17681
                                          carbamoyl group 17551
                                            carboxamide 17551
                                              peptide 11122
                                                cyclic peptide 8874
                                                  heterodetic cyclic peptide 1652
                                                    polymyxin 80
                                                      colistin A 34
                                                        colistin 34
                                                          colistimethate sodium 0
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