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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:clavulone II
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Accession:CHEBI:34643 term browser browse the term
Definition:A clavulone that has formula C25H34O7.
Synonyms:exact_synonym: methyl (4R,5E,7E,14Z)-4,12-bis(acetyloxy)-9-oxo-12alpha-prosta-5,7,10,14-tetraen-1-oate
 related_synonym: Formula=C25H34O7;   InChI=1S/C25H34O7/c1-5-6-7-8-9-10-17-25(32-20(3)27)18-16-23(28)22(25)13-11-12-21(31-19(2)26)14-15-24(29)30-4/h9-13,16,18,21H,5-8,14-15,17H2,1-4H3/b10-9-,12-11+,22-13-/t21-,25-/m0/s1;   InChIKey=QXSYLWTUKSQQCP-VZCZYXORSA-N;   SMILES=CCCCC\\C=C/C[C@]1(OC(C)=O)C=CC(=O)/C1=C/C=C/[C@@H](CCC(=O)OC)OC(C)=O
 xref: Beilstein:3658162;   CAS:85700-43-2;   KEGG:C13812;   LIPID_MAPS_instance:LMFA03120002
 xref_mesh: MESH:C057741


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clavulone II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO clavulone II results in increased expression of BAX protein CTD PMID:15920677 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage ISO clavulone II results in increased cleavage of BID protein CTD PMID:15920677 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Casp3 caspase 3 increases activity ISO clavulone II results in increased activity of CASP3 protein CTD PMID:15920677 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO clavulone II results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:15920677 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO clavulone II results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:15920677 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO clavulone II results in decreased expression of CCND1 protein CTD PMID:15920677 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO clavulone II results in decreased expression of MCL1 protein CTD PMID:15920677 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link

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  CHEBI ontology 19812
    role 19761
      application 19471
        fuel 11017
          methanol 3858
            methyl ester 3830
              clavulone II 7
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  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        monocarboxylic acid 17632
                                          fatty acid 16012
                                            fatty acid derivative 1047
                                              icosanoid 460
                                                prostanoid 399
                                                  clavulone 7
                                                    clavulone II 7
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