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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:34632 term browser browse the term
Definition:An organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.
Synonyms:exact_synonym: O,O-dimethyl O-(3,5,6-trichloropyridin-2-yl) phosphorothioate
 related_synonym: Chloropyriphos-methyl;   Chlorpyrifos O,O-dimethyl analog;   Formula=C7H7Cl3NO3PS;   InChI=1S/C7H7Cl3NO3PS/c1-12-15(16,13-2)14-7-5(9)3-4(8)6(10)11-7/h3H,1-2H3;   InChIKey=HRBKVYFZANMGRE-UHFFFAOYSA-N;   Methyl chlorpyriphos;   O,O-dimethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate;   Phosphorothioic acid, O,O-dimethyl O-(3,5,6-trichloro-2-pyridinyl) ester;   Phosphorothioic acid, O,O-dimethyl O-(3,5,6-trichloro-2-pyridyl) ester;   SMILES=COP(=S)(OC)Oc1nc(Cl)c(Cl)cc1Cl;   Trichlormethylfos;   o,o-Dimethyl-o-(3,5,6-trichloro-2-pyridyl)phosphorothioate
 xref: Beilstein:1541078;   CAS:5598-13-0;   KEGG:C14520
 xref_mesh: MESH:C007031
 xref: PPDB:155;   Pesticides:chlorpyrifos-methyl;   Reaxys:1541078

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chlorpyrifos-methyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects activity
multiple interactions
ISO chlorpyrifos-methyl affects the activity of ABCB1 protein
chlorpyrifos-methyl affects the reaction [ABCB1 protein results in increased transport of calcein AM]
CTD PMID:21783720 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO chlorpyrifos-methyl binds to and results in increased activity of AHR protein CTD PMID:23436777 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ar androgen receptor affects binding ISO chlorpyrifos-methyl binds to AR protein CTD PMID:23436777 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Cnr1 cannabinoid receptor 1 decreases activity
multiple interactions
ISO chlorpyrifos-methyl results in decreased activity of CNR1 protein
chlorpyrifos-methyl inhibits the reaction [CP 55244 binds to CNR1 protein]
CTD PMID:12243867 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO chlorpyrifos-methyl results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO chlorpyrifos-methyl inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link

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  CHEBI ontology 19770
    role 19720
      application 19411
        agrochemical 14673
          chlorpyrifos-methyl 6
Path 2
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  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      chalcogen 19391
                        oxygen atom 19354
                          oxygen molecular entity 19354
                            hydroxides 19077
                              oxoacid 18278
                                pnictogen oxoacid 10308
                                  phosphorus oxoacid 9229
                                    phosphoric acids 7949
                                      phosphoric acid 7949
                                        phosphoric acid derivative 7630
                                          phosphate 7630
                                            organic phosphate 7629
                                              organic thiophosphate 2893
                                                chlorpyrifos-methyl 6
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