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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chlorpropham
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Accession:CHEBI:34630 term browser browse the term
Definition:A carbamate ester that is the isopropyl ester of 3-chlorophenylcarbamic acid.
Synonyms:exact_synonym: propan-2-yl (3-chlorophenyl)carbamate
 related_synonym: (3-Chlorophenyl)carbamic acid, 1-methylethyl ester;   1-Methylethyl (3-chlorophenyl)carbamate;   3-Chlorocarbanilic acid, isopropyl ester;   Chloropropham;   Chlorprophame;   Formula=C10H12ClNO2;   InChI=1S/C10H12ClNO2/c1-7(2)14-10(13)12-9-5-3-4-8(11)6-9/h3-7H,1-2H3,(H,12,13);   InChIKey=CWJSHJJYOPWUGX-UHFFFAOYSA-N;   Isopropyl 3-chlorocarbanilate;   Isopropyl 3-chlorophenylcarbamate;   Isopropyl meta-chlorocarbanilate;   Isopropyl-N-(3-chlorphenyl)-carbamat;   Isopropyl-N-3-chlorophenyl carbamate;   Isopropyl-N-m-chlorophenyl-carbamate;   Isopropyl-m-chlorocarbanilate;   N-(3-Chlorophenyl)carbamic acid, isopropyl ester;   N-3-Chlorophenylisopropylcarbamate;   O-Isopropyl N-(3-chlorophenyl)carbamate;   SMILES=CC(C)OC(=O)Nc1cccc(Cl)c1;   isopropyl (3-chlorophenyl)carbamate;   m-Chlorocarbanilic acid isopropyl ester
 xref: Beilstein:2211397;   CAS:101-21-3;   KEGG:C14506
 xref_mesh: MESH:D002748
 xref: PMID:21757399;   PMID:22753523;   PMID:22982221;   PMID:23295769;   PMID:23674283;   PMID:23708426;   PMID:24166079;   PPDB:153;   Reaxys:2211397;   Wikipedia:Chlorpropham

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chlorpropham term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 decreases response to substance ISO ABCC1 protein results in decreased susceptibility to Chlorpropham CTD PMID:12765240 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Chlorpropham binds to and results in increased activity of AHR protein CTD PMID:18835618 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ar androgen receptor increases expression
multiple interactions		 ISO Chlorpropham results in increased expression of AR mRNA
Chlorpropham inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]		 CTD PMID:21310686 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [Maleic Hydrazide co-treated with Chlorpropham] results in increased expression of CYP3A4 mRNA CTD PMID:25028461 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [Maleic Hydrazide co-treated with Chlorpropham] results in increased activity of NR1I2 protein; Chlorpropham binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 PMID:25028461 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Chlorpropham binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2 CTD PMID:26359731 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        pesticide 16979
          herbicide 12441
            chlorpropham 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic ester 15884
                                        carbamate ester 7445
                                          chlorpropham 6
paths to the root