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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chlorpropham
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Accession:CHEBI:34630 term browser browse the term
Definition:A carbamate ester that is the isopropyl ester of 3-chlorophenylcarbamic acid.
Synonyms:exact_synonym: propan-2-yl (3-chlorophenyl)carbamate
 related_synonym: (3-Chlorophenyl)carbamic acid, 1-methylethyl ester;   1-Methylethyl (3-chlorophenyl)carbamate;   3-Chlorocarbanilic acid, isopropyl ester;   Chloropropham;   Chlorprophame;   Formula=C10H12ClNO2;   InChI=1S/C10H12ClNO2/c1-7(2)14-10(13)12-9-5-3-4-8(11)6-9/h3-7H,1-2H3,(H,12,13);   InChIKey=CWJSHJJYOPWUGX-UHFFFAOYSA-N;   Isopropyl 3-chlorocarbanilate;   Isopropyl 3-chlorophenylcarbamate;   Isopropyl meta-chlorocarbanilate;   Isopropyl-N-(3-chlorphenyl)-carbamat;   Isopropyl-N-3-chlorophenyl carbamate;   Isopropyl-N-m-chlorophenyl-carbamate;   Isopropyl-m-chlorocarbanilate;   N-(3-Chlorophenyl)carbamic acid, isopropyl ester;   N-3-Chlorophenylisopropylcarbamate;   O-Isopropyl N-(3-chlorophenyl)carbamate;   SMILES=CC(C)OC(=O)Nc1cccc(Cl)c1;   isopropyl (3-chlorophenyl)carbamate;   m-Chlorocarbanilic acid isopropyl ester
 xref: Beilstein:2211397;   CAS:101-21-3;   KEGG:C14506
 xref_mesh: MESH:D002748
 xref: PMID:21757399;   PMID:22753523;   PMID:22982221;   PMID:23295769;   PMID:23674283;   PMID:23708426;   PMID:24166079;   PPDB:153;   Reaxys:2211397;   Wikipedia:Chlorpropham

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chlorpropham term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 decreases response to substance ISO ABCC1 protein results in decreased susceptibility to Chlorpropham CTD PMID:12765240 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Chlorpropham binds to and results in increased activity of AHR protein CTD PMID:18835618 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464 		JBrowse link
G Ar androgen receptor increases expression
multiple interactions		 ISO Chlorpropham results in increased expression of AR mRNA
Chlorpropham inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]		 CTD PMID:21310686 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [Maleic Hydrazide co-treated with Chlorpropham] results in increased activity of NR1I2 protein; Chlorpropham binds to and results in increased activity of NR1I2 protein CTD PMID:21115097, PMID:25028461 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Chlorpropham binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2 CTD PMID:26359731 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        pesticide 16263
          herbicide 11200
            chlorpropham 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic ester 14073
                                        carbamate ester 7378
                                          chlorpropham 5
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