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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:carbofuran
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Accession:CHEBI:34611 term browser browse the term
Definition:A 1-benzofuran that has formula C12H15NO3.
Synonyms:exact_synonym: 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate
 related_synonym: 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl N-methylcarbamate;   2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate;   Formula=C12H15NO3;   Furadan;   InChI=1S/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14);   InChIKey=DUEPRVBVGDRKAG-UHFFFAOYSA-N;   SMILES=CNC(=O)Oc1cccc2CC(C)(C)Oc12
 xref: Beilstein:1428746;   Beilstein:8312603;   CAS:1563-66-2;   KEGG:C14291;   LINCS:LSM-3186
 xref_mesh: MESH:D002235
 xref: PPDB:118


show annotations for term's descendants           Sort by:
carbofuran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase (P blood group) affects response to substance ISO A4GALT gene SNP affects the susceptibility to Carbofuran CTD PMID:22919386 NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071 		JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase increases expression EXP Carbofuran results in increased expression of ABHD2 mRNA CTD PMID:20211217 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061 		JBrowse link
G Ache acetylcholinesterase decreases activity ISO
EXP		 Carbofuran results in decreased activity of ACHE protein CTD PMID:7966439 PMID:10918524 PMID:19934164 PMID:22209767 PMID:22807346 More... NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP Carbofuran results in increased expression of ADAM8 mRNA CTD PMID:20211217 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Alb albumin affects binding
multiple interactions
increases secretion		 ISO
EXP		 Carbofuran binds to ALB protein
Plant Extracts inhibits the reaction [Carbofuran results in increased secretion of ALB protein]; Silymarin inhibits the reaction [Carbofuran results in increased secretion of ALB protein]		 CTD PMID:27657490 PMID:34264070 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP Carbofuran results in increased expression of BAX protein
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in increased expression of BAX protein]		 CTD PMID:28982980 PMID:30471306 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression EXP Carbofuran results in increased expression of BCAT1 mRNA CTD PMID:20211217 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Bche butyrylcholinesterase decreases activity
multiple interactions		 ISO
EXP		 Carbofuran results in decreased activity of BCHE protein
[Carbaryl co-treated with Propoxur co-treated with Methiocarb co-treated with Methomyl co-treated with formetanate co-treated with oxamyl co-treated with Carbofuran] affects the activity of BCHE protein		 CTD PMID:17364237 PMID:22209767 PMID:22649187 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Carbofuran results in decreased expression of BCL2 protein CTD PMID:30471306 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 decreases expression
multiple interactions
increases expression		 EXP
ISO		 Carbofuran results in decreased expression of CASP3 protein modified form
Carbofuran results in increased cleavage of and results in increased activity of CASP3 protein
Carbofuran results in increased expression of CASP3 protein modified form
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in increased expression of CASP3 protein modified form]		 CTD PMID:22240977 PMID:25564422 PMID:28982980 PMID:30471306 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions
decreases activity		 EXP Plant Extracts inhibits the reaction [Carbofuran results in decreased activity of CAT protein]; Silymarin inhibits the reaction [Carbofuran results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Carbofuran results in decreased activity of CAT protein] CTD PMID:22807346 PMID:24865641 PMID:31334637 PMID:31696704 PMID:34264070 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP Carbofuran results in increased expression of CCL7 mRNA CTD PMID:20211217 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 EXP Carbofuran results in decreased expression of CCND1 mRNA; Carbofuran results in decreased expression of CCND1 protein
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in decreased expression of CCND1 protein]		 CTD PMID:28982980 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression EXP Carbofuran results in increased expression of CCR1 mRNA CTD PMID:20211217 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd14 CD14 molecule increases expression EXP Carbofuran results in increased expression of CD14 mRNA CTD PMID:20211217 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cdk7 cyclin-dependent kinase 7 affects response to substance ISO CDK7 gene SNP affects the susceptibility to Carbofuran CTD PMID:22102698 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 EXP 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in increased expression of CDKN1A protein]
Carbofuran results in increased expression of CDKN1A mRNA; Carbofuran results in increased expression of CDKN1A protein		 CTD PMID:28982980 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression EXP Carbofuran results in increased expression of CH25H mRNA CTD PMID:20211217 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression EXP Carbofuran results in decreased expression of CNP mRNA; Carbofuran results in decreased expression of CNP protein CTD PMID:28982980 PMID:30471306 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Crem cAMP responsive element modulator increases expression EXP Carbofuran results in increased expression of CREM mRNA CTD PMID:20211217 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases hydroxylation ISO CYP1A2 protein results in increased hydroxylation of Carbofuran CTD PMID:15560889 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases activity
increases expression		 ISO Carbofuran results in increased activity of CYP2B6 protein
Carbofuran results in increased expression of CYP2B6 mRNA		 CTD PMID:22310298 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases hydroxylation ISO CYP2C19 protein results in increased hydroxylation of Carbofuran CTD PMID:15560889 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases hydroxylation
increases activity
increases chemical synthesis
increases expression
multiple interactions		 ISO CYP3A4 protein results in increased hydroxylation of Carbofuran
Carbofuran results in increased activity of CYP3A4 protein
CYP3A4 protein results in increased chemical synthesis of Carbofuran
Carbofuran results in increased expression of CYP3A4 mRNA
[CYP3A4 protein results in increased metabolism of benfuracarb] which results in increased chemical synthesis of Carbofuran; Carbofuran promotes the reaction [CYP3A4 protein affects the metabolism of Testosterone]; Chlorpyrifos inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Carbofuran]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Carbofuran]		 CTD PMID:15560889 PMID:22310298 PMID:24016712 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dcx doublecortin decreases expression
multiple interactions		 EXP Carbofuran results in decreased expression of DCX mRNA; Carbofuran results in decreased expression of DCX protein
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in decreased expression of DCX protein]		 CTD PMID:22240977 PMID:28982980 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476 		JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression EXP Carbofuran results in increased expression of FABP3 protein CTD PMID:19854236 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP Carbofuran results in increased expression of FCGR2B mRNA CTD PMID:20211217 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression EXP Carbofuran results in increased expression of FHL1 mRNA CTD PMID:20211217 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression EXP Carbofuran results in increased expression of FOSL1 mRNA CTD PMID:20211217 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
increases expression		 EXP Carbofuran results in decreased expression of GFAP protein
Carbofuran results in increased expression of GFAP mRNA		 CTD PMID:22240977 PMID:28982980 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity		 EXP Plant Extracts inhibits the reaction [Carbofuran results in increased activity of GPT protein]; Silymarin inhibits the reaction [Carbofuran results in increased activity of GPT protein] CTD PMID:31334637 PMID:31696704 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Carbofuran results in decreased expression of GRIA2 protein CTD PMID:28725974 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression EXP Carbofuran results in increased expression of HAMP mRNA CTD PMID:20211217 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression EXP Carbofuran results in increased expression of HSPA2 mRNA CTD PMID:20211217 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Il2 interleukin 2 decreases response to substance ISO Carbofuran results in decreased susceptibility to IL2 protein CTD PMID:8349949 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Klhl40 kelch-like family member 40 increases expression EXP Carbofuran results in increased expression of KLHL40 mRNA CTD PMID:20211217 NCBI chr 8:121,441,275...121,446,806
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Klhl41 kelch-like family member 41 increases expression EXP Carbofuran results in increased expression of KLHL41 mRNA CTD PMID:20211217 NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222 		JBrowse link
G Ldlr low density lipoprotein receptor affects response to substance ISO LDLR gene SNP affects the susceptibility to Carbofuran CTD PMID:22919386 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Carbofuran results in increased expression of LMCD1 mRNA CTD PMID:20211217 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046 		JBrowse link
G Mag myelin-associated glycoprotein decreases expression EXP Carbofuran results in decreased expression of MAG mRNA; Carbofuran results in decreased expression of MAG protein CTD PMID:30471306 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Mbp myelin basic protein decreases expression EXP Carbofuran results in decreased expression of MBP mRNA; Carbofuran results in decreased expression of MBP protein CTD PMID:28982980 PMID:30471306 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mtnr1a melatonin receptor 1A affects binding
multiple interactions		 ISO Carbofuran binds to MTNR1A protein
Carbofuran inhibits the reaction [Melatonin binds to MTNR1A protein]		 CTD PMID:28027439 NCBI chr16:47,144,461...47,163,919
Ensembl chr16:47,144,461...47,163,919 		JBrowse link
G Mtnr1b melatonin receptor 1B affects binding
multiple interactions		 ISO Carbofuran binds to MTNR1B protein
Carbofuran inhibits the reaction [Melatonin binds to MTNR1B protein]; Guanosine Triphosphate inhibits the reaction [Carbofuran inhibits the reaction [Melatonin binds to MTNR1B protein]]		 CTD PMID:28027439 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression
multiple interactions		 EXP
ISO		 Carbofuran results in increased expression of MYC mRNA
Carbofuran results in decreased stability of and results in increased degradation of and results in increased mutagenesis of MYC gene		 CTD PMID:20211217 PMID:22445671 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myl1 myosin, light chain 1 increases expression EXP Carbofuran results in increased expression of MYL1 protein CTD PMID:19854236 NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261 		JBrowse link
G Myrf myelin regulatory factor decreases expression EXP Carbofuran results in decreased expression of MYRF mRNA CTD PMID:30471306 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G Nes nestin decreases expression EXP Carbofuran results in decreased expression of NES mRNA CTD PMID:22240977 PMID:28982980 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Neurod1 neuronal differentiation 1 decreases expression EXP Carbofuran results in decreased expression of NEUROD1 mRNA CTD PMID:22240977 PMID:28982980 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Neurog2 neurogenin 2 decreases expression EXP Carbofuran results in decreased expression of NEUROG2 mRNA CTD PMID:28982980 NCBI chr 2:216,092,641...216,095,276
Ensembl chr 2:216,093,363...216,094,154 		JBrowse link
G Nrg1 neuregulin 1 decreases expression EXP Carbofuran results in decreased expression of NRG1 mRNA CTD PMID:28982980 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Olig1 oligodendrocyte transcription factor 1 decreases expression EXP Carbofuran results in decreased expression of OLIG1 mRNA CTD PMID:28982980 NCBI chr11:30,514,379...30,516,521
Ensembl chr11:30,514,379...30,516,521 		JBrowse link
G Olig2 oligodendrocyte transcription factor 2 decreases expression EXP Carbofuran results in decreased expression of OLIG2 mRNA; Carbofuran results in decreased expression of OLIG2 protein CTD PMID:30471306 NCBI chr11:30,475,510...30,478,886
Ensembl chr11:30,475,398...30,480,152 		JBrowse link
G Pax6 paired box 6 decreases expression EXP Carbofuran results in decreased expression of PAX6 mRNA CTD PMID:28982980 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha decreases expression EXP Carbofuran results in decreased expression of PDGFRA mRNA; Carbofuran results in decreased expression of PDGFRA protein CTD PMID:30471306 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pla2g4a phospholipase A2 group IVA increases expression EXP Carbofuran results in increased expression of PLA2G4A mRNA CTD PMID:20211217 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Plau plasminogen activator, urokinase increases expression EXP Carbofuran results in increased expression of PLAU mRNA CTD PMID:20211217 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plp1 proteolipid protein 1 decreases expression EXP Carbofuran results in decreased expression of PLP1 mRNA; Carbofuran results in decreased expression of PLP1 protein CTD PMID:30471306 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Pvr PVR cell adhesion molecule increases expression EXP Carbofuran results in increased expression of PVR mRNA CTD PMID:20211217 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
G Rbfox3 RNA binding fox-1 homolog 3 decreases expression
multiple interactions		 EXP Carbofuran results in decreased expression of RBFOX3 protein
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in decreased expression of RBFOX3 protein]		 CTD PMID:28982980 NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935 		JBrowse link
G Reg3b regenerating family member 3 beta increases expression EXP Carbofuran results in increased expression of REG3B mRNA CTD PMID:20211217 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015 		JBrowse link
G Rnd1 Rho family GTPase 1 increases expression EXP Carbofuran results in increased expression of RND1 mRNA CTD PMID:20211217 NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399 		JBrowse link
G S100b S100 calcium binding protein B increases expression EXP Carbofuran results in increased expression of S100B mRNA; Carbofuran results in increased expression of S100B protein CTD PMID:28982980 PMID:30471306 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Serpine1 serpin family E member 1 increases expression EXP Carbofuran results in increased expression of SERPINE1 mRNA CTD PMID:20211217 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Smad2 SMAD family member 2 increases expression
increases phosphorylation
multiple interactions		 EXP Carbofuran results in increased expression of SMAD2 mRNA
Carbofuran results in increased phosphorylation of SMAD2 protein
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in increased phosphorylation of SMAD2 protein]		 CTD PMID:28982980 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 increases expression
increases phosphorylation
multiple interactions		 EXP Carbofuran results in increased expression of SMAD3 mRNA
Carbofuran results in increased phosphorylation of SMAD3 protein
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in increased phosphorylation of SMAD3 protein]		 CTD PMID:28982980 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad7 SMAD family member 7 decreases expression EXP Carbofuran results in decreased expression of SMAD7 mRNA; Carbofuran results in decreased expression of SMAD7 protein CTD PMID:28982980 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 decreases expression EXP Carbofuran results in decreased expression of SMURF2 mRNA CTD PMID:28982980 NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488 		JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression EXP Carbofuran results in decreased expression of SOX2 protein CTD PMID:22240977 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP Carbofuran results in increased expression of SPP1 mRNA CTD PMID:20211217 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP Carbofuran results in increased expression of STAT3 mRNA CTD PMID:22240977 PMID:28982980 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Carbofuran results in increased expression of TGFB1 mRNA; Carbofuran results in increased expression of TGFB1 protein CTD PMID:28982980 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Carbofuran results in increased expression of TGFB2 mRNA CTD PMID:20211217 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 increases expression EXP Carbofuran results in increased expression of TIAM1 mRNA CTD PMID:20211217 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP Carbofuran results in increased expression of TIMP1 mRNA CTD PMID:20211217 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnni3 troponin I3, cardiac type increases expression EXP Carbofuran results in increased expression of TNNI3 protein CTD PMID:19854236 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580 		JBrowse link
G Tnnt2 troponin T2, cardiac type increases expression EXP Carbofuran results in increased expression of TNNT2 protein CTD PMID:19854236 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Carbofuran results in decreased stability of and results in increased degradation of and results in increased mutagenesis of TP53 gene CTD PMID:22445671 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression EXP Carbofuran results in decreased expression of TUBB3 mRNA CTD PMID:28982980 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243 		JBrowse link
G Tubb6 tubulin, beta 6 class V increases expression EXP Carbofuran results in increased expression of TUBB6 mRNA CTD PMID:20211217 NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418 		JBrowse link
G Uck2 uridine-cytidine kinase 2 increases expression EXP Carbofuran results in increased expression of UCK2 mRNA CTD PMID:20211217 NCBI chr13:79,380,807...79,438,352
Ensembl chr13:79,383,846...79,438,352 		JBrowse link
G Vcan versican increases expression
decreases expression		 EXP Carbofuran results in increased expression of VCAN mRNA
Carbofuran results in decreased expression of VCAN mRNA		 CTD PMID:20211217 PMID:30471306 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      application 19622
        agrochemical 15690
          carbofuran 81
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic group 18905
                              organic divalent group 18887
                                organodiyl group 18887
                                  carbonyl group 18853
                                    carbonyl compound 18853
                                      carboxylic ester 15998
                                        carbamate ester 7501
                                          carbofuran 81
paths to the root