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G |
B3gat1 |
beta-1,3-glucuronyltransferase 1 |
multiple interactions |
EXP |
[bromodichloromethane co-treated with Dietary Fats] results in increased expression of B3GAT1 protein |
CTD |
PMID:24211274 |
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NCBI chr 9:26,644,813...26,672,646
Ensembl chr 9:26,645,024...26,674,397
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G |
Casp3 |
caspase 3 |
multiple interactions |
EXP |
[bromodichloromethane co-treated with Dietary Fats] results in increased expression of CASP3 protein modified form; [PRF1 protein co-treated with RAG2 protein] affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of CASP3 protein modified form]; LEP protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of CASP3 protein modified form] |
CTD |
PMID:24211274 |
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NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
EXP |
bromodichloromethane promotes the reaction [Dietary Fats results in increased expression of CCL2 protein] |
CTD |
PMID:23438451 |
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NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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G |
Ccnd1 |
cyclin D1 |
increases expression |
ISO |
bromodichloromethane results in increased expression of CCND1 mRNA |
CTD |
PMID:24001804 |
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NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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G |
Cd68 |
CD68 antigen |
multiple interactions |
EXP |
[Dietary Fats co-treated with bromodichloromethane] results in increased expression of CD68 mRNA; gadolinium chloride inhibits the reaction [[Dietary Fats co-treated with bromodichloromethane] results in increased expression of CD68 mRNA] |
CTD |
PMID:23438451 |
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NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979
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G |
Cdh1 |
cadherin 1 |
decreases expression increases methylation |
ISO |
bromodichloromethane results in decreased expression of CDH1 mRNA; bromodichloromethane results in decreased expression of CDH1 protein bromodichloromethane results in increased methylation of CDH1 gene |
CTD |
PMID:24001804 |
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NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases metabolic processing decreases expression increases expression affects metabolic processing multiple interactions |
ISO |
CYP1A2 protein results in increased metabolism of bromodichloromethane bromodichloromethane results in decreased expression of CYP1A2 protein bromodichloromethane results in increased expression of CYP1A2 protein CYP1A2 protein affects the metabolism of bromodichloromethane isosafrole inhibits the reaction [CYP1A2 protein affects the metabolism of bromodichloromethane]; Tetrachlorodibenzodioxin promotes the reaction [CYP1A2 protein affects the metabolism of bromodichloromethane] |
CTD |
PMID:11295256 PMID:12062927 PMID:12076521 |
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NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
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G |
Cyp2a5 |
cytochrome P450, family 2, subfamily a, polypeptide 5 |
increases metabolic processing |
ISO |
CYP2A6 protein results in increased metabolism of bromodichloromethane |
CTD |
PMID:12076521 |
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NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
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G |
Cyp2b13 |
cytochrome P450, family 2, subfamily b, polypeptide 13 |
increases metabolic processing |
ISO |
CYP2B2 protein results in increased metabolism of bromodichloromethane |
CTD |
PMID:12076521 |
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NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression increases metabolic processing decreases response to substance |
ISO EXP |
CYP2E1 protein results in increased metabolism of and results in increased activity of bromodichloromethane bromodichloromethane results in increased expression of CYP2E1 protein CYP2E1 protein results in increased metabolism of bromodichloromethane CYP2E1 gene mutant form results in decreased susceptibility to bromodichloromethane [Dietary Fats co-treated with bromodichloromethane] results in increased expression of CYP2E1 protein; CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IFNG mRNA]; CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL1B mRNA]; CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA]; CYP2E1 protein affects the susceptibility to [bromodichloromethane co-treated with Dietary Fats] |
CTD |
PMID:9458004 PMID:11295256 PMID:12076521 PMID:12076522 PMID:18350910 PMID:23438451 PMID:23640861 PMID:24211274 More...
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NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
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G |
Gpt |
glutamic pyruvic transaminase, soluble |
increases expression |
EXP |
bromodichloromethane results in increased expression of GPT |
CTD |
PMID:25640707 |
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NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
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G |
Gstt1 |
glutathione S-transferase, theta 1 |
increases metabolic processing multiple interactions |
EXP ISO |
GSTT1 protein results in increased metabolism of bromodichloromethane GSTT1 protein affects the metabolism of [bromodichloromethane co-treated with Glutathione] |
CTD |
PMID:12588193 PMID:14998683 |
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NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
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G |
Ifng |
interferon gamma |
multiple interactions |
EXP |
[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IFNG mRNA; CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IFNG mRNA] |
CTD |
PMID:24211274 |
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NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL1B mRNA; CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL1B mRNA] |
CTD |
PMID:24211274 |
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NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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G |
Il2 |
interleukin 2 |
multiple interactions |
EXP |
[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA; [PRF1 protein co-treated with RAG2 protein] affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA]; CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA] |
CTD |
PMID:24211274 |
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NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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G |
Jun |
jun proto-oncogene |
decreases expression |
ISO |
bromodichloromethane results in decreased expression of JUN mRNA |
CTD |
PMID:24001804 |
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NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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G |
Lep |
leptin |
increases expression decreases response to substance multiple interactions |
EXP |
bromodichloromethane results in increased expression of LEP mRNA LEP gene mutant form results in decreased susceptibility to bromodichloromethane bromodichloromethane promotes the reaction [Dietary Fats results in increased expression of LEP mRNA]; LEP protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of CASP3 protein modified form]; LEP protein affects the reaction [[Dietary Fats co-treated with bromodichloromethane] affects the localization of NCF2 protein]; LEP protein results in decreased susceptibility to [Dietary Fats co-treated with bromodichloromethane] |
CTD |
PMID:23438451 PMID:23640861 PMID:24211274 |
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NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
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G |
Lepr |
leptin receptor |
multiple interactions |
EXP |
LEPR protein affects the reaction [[Dietary Fats co-treated with bromodichloromethane] affects the localization of NCF2 protein]; LEPR protein results in decreased susceptibility to [Dietary Fats co-treated with bromodichloromethane] |
CTD |
PMID:23438451 |
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NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
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G |
Lhb |
luteinizing hormone beta |
decreases secretion |
ISO |
bromodichloromethane results in decreased secretion of LHB protein |
CTD |
PMID:14657523 PMID:17344021 |
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NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
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G |
Myc |
myelocytomatosis oncogene |
decreases methylation decreases expression increases expression |
EXP ISO |
bromodichloromethane results in decreased methylation of MYC promoter bromodichloromethane results in decreased expression of MYC mRNA bromodichloromethane results in increased expression of MYC mRNA |
CTD |
PMID:11099637 PMID:24001804 |
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NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
multiple interactions |
EXP |
[Dietary Fats co-treated with bromodichloromethane] affects the localization of NCF2 protein; LEP protein affects the reaction [[Dietary Fats co-treated with bromodichloromethane] affects the localization of NCF2 protein]; LEPR protein affects the reaction [[Dietary Fats co-treated with bromodichloromethane] affects the localization of NCF2 protein] |
CTD |
PMID:23438451 |
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NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742
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G |
Pcna |
proliferating cell nuclear antigen |
increases expression |
EXP ISO |
bromodichloromethane results in increased expression of PCNA protein |
CTD |
PMID:8717228 PMID:11099637 |
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NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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G |
Prf1 |
perforin 1 (pore forming protein) |
multiple interactions |
EXP |
[PRF1 protein co-treated with RAG2 protein] affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of CASP3 protein modified form]; [PRF1 protein co-treated with RAG2 protein] affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA]; [PRF1 protein co-treated with RAG2 protein] affects the susceptibility to [bromodichloromethane co-treated with Dietary Fats] |
CTD |
PMID:24211274 |
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NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
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G |
Rag2 |
recombination activating gene 2 |
multiple interactions |
EXP |
[PRF1 protein co-treated with RAG2 protein] affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of CASP3 protein modified form]; [PRF1 protein co-treated with RAG2 protein] affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA]; [PRF1 protein co-treated with RAG2 protein] affects the susceptibility to [bromodichloromethane co-treated with Dietary Fats] |
CTD |
PMID:24211274 |
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NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP |
[Dietary Fats co-treated with bromodichloromethane] results in increased expression of TNF protein |
CTD |
PMID:23438451 |
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NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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