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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:boldenone
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Accession:CHEBI:34584 term browser browse the term
Definition:An 3-oxo-Delta(1),Delta(4)-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been developed for veterinary use.
Synonyms:exact_synonym: (17beta)-17-hydroxyandrosta-1,4-dien-3-one
 related_synonym: 1,2-Dehydrotestosterone;   1,2-Didehydrotestosterone;   1,4-Androstadien-17beta-ol-3-one;   17beta-Boldenone;   17beta-hydroxyandrosta-1,4-dien-3-one;   Formula=C19H26O2;   InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-17,21H,3-6,8,10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1;   InChIKey=RSIHSRDYCUFFLA-DYKIIFRCSA-N;   SMILES=C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@@H]2O;   boldenona;   boldenonum
 xref: Beilstein:2625467;   CAS:846-48-0;   DrugBank:DB01541;   KEGG:C14502;   KEGG:D07536;   LIPID_MAPS_instance:LMST02020018
 xref_mesh: MESH:C013915
 xref: PMID:17084871;   PMID:23534422;   PMID:24097356;   PMID:24259377;   Patent:US2837464;   Patent:US2875196;   Reaxys:2625467;   Wikipedia:Boldenone


show annotations for term's descendants           Sort by:
boldenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpx5 glutathione peroxidase 5 increases expression ISO boldenone results in increased expression of GPX5 mRNA CTD PMID:1301385 NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of IL1B mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of IL1B mRNA] CTD PMID:34719837 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of MYD88 mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of MYD88 mRNA] CTD PMID:34719837 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of RELA protein; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of RELA protein] CTD PMID:34719837 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TLR4 protein; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TLR4 protein] CTD PMID:34719837 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TNF mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TNF mRNA] CTD PMID:34719837 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TRAF6 mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TRAF6 mRNA] CTD PMID:34719837 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    role 19825
      biological role 19823
        molecular messenger 18637
          hormone 18484
            steroid hormone 7897
              anabolic androgenic steroid 437
                boldenone 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19797
                    p-block element atom 19797
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            heteroorganic entity 19492
                              organochalcogen compound 19254
                                organooxygen compound 19170
                                  carbonyl compound 18893
                                    ketone 17191
                                      oxo steroid 10545
                                        3-oxo steroid 9934
                                          3-oxo-Delta(1) steroid 5225
                                            3-oxo-Delta(1),Delta(4)-steroid 5225
                                              boldenone 7
paths to the root