Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Azimilide
go back to main search page
Accession:CHEBI:34545 term browser browse the term
Definition:An imidazolidine-2,4-dione that has formula C23H28ClN5O3.
Synonyms:related_synonym: Formula=C23H28ClN5O3;   InChI=1S/C23H28ClN5O3/c1-26-12-14-27(15-13-26)10-2-3-11-28-22(30)17-29(23(28)31)25-16-20-8-9-21(32-20)18-4-6-19(24)7-5-18/h4-9,16H,2-3,10-15,17H2,1H3/b25-16+;   InChIKey=MREBEPTUUMTTIA-PCLIKHOPSA-N;   SMILES=CN1CCN(CCCCN2C(=O)CN(\\N=C\\c3ccc(o3)-c3ccc(Cl)cc3)C2=O)CC1;   azimilide HCl;   azimilide dihydrochloride;   azimilide hydrochloride
 xref: CAS:149908-53-2;   Drug_Central:274;   KEGG:C13777
 xref_mesh: MESH:C086123


show annotations for term's descendants           Sort by:
 
Azimilide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions
ISO azimilide results in decreased activity of KCNH2 protein
Acids inhibits the reaction [azimilide results in decreased activity of KCNH2 protein]; azimilide promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [azimilide results in decreased activity of KCNH2 protein]; Potassium inhibits the reaction [azimilide results in decreased activity of KCNH2 protein]
CTD PMID:15821840 PMID:16960444 PMID:18057881 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      atom 19771
        nonmetal atom 19654
          nitrogen atom 18583
            nitrogen molecular entity 18583
              organonitrogen compound 18371
                organonitrogen heterocyclic compound 17526
                  diazolidine 589
                    imidazolidines 579
                      imidazolidinone 481
                        imidazolidine-2,4-dione 460
                          Azimilide 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            organic molecule 19505
                              organic cyclic compound 19332
                                organic heterocyclic compound 18519
                                  organic heteromonocyclic compound 16987
                                    diazolidine 589
                                      imidazolidines 579
                                        imidazolidinone 481
                                          imidazolidine-2,4-dione 460
                                            Azimilide 1
paths to the root