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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:8,9-EET
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Accession:CHEBI:34490 term browser browse the term
Definition:An EET obtained by formal epoxidation of the 8,9-double bond of arachidonic acid.
Synonyms:exact_synonym: (5Z)-7-{3-[(2Z,5Z)-undeca-2,5-dien-1-yl]oxiran-2-yl}hept-5-enoic acid
 related_synonym: (+/-)8,9-EpETrE;   (5Z,11Z,14Z)-8,9-Epoxyeicosa-5,11,14-trienoic acid;   (5Z,11Z,14Z)-8,9-Epoxyicosa-5,11,14-trienoic acid;   8,9-Epoxyeicosatrienoic acid;   8,9-epoxy-5Z,11Z,14Z-eicosatrienoic acid;   8,9-epoxy-5Z,11Z,14Z-icosatrienoic acid;   8,9-epoxyicosatrienoic acid;   Formula=C20H32O3;   InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-12-15-18-19(23-18)16-13-10-11-14-17-20(21)22/h6-7,9-10,12-13,18-19H,2-5,8,11,14-17H2,1H3,(H,21,22)/b7-6-,12-9-,13-10-;   InChIKey=DBWQSCSXHFNTMO-TYAUOURKSA-N;   SMILES=CCCCC\\C=C/C\\C=C/CC1OC1C\\C=C/CCCC(O)=O
 alt_id: CHEBI:63972
 xref: HMDB:HMDB0002232;   KEGG:C14769;   LIPID_MAPS_instance:LMFA03080003
 xref_mesh: MESH:C050715
 xref: Reaxys:4697201
 cyclic_relationship: is_conjugate_acid_of CHEBI:84025


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8,9-EET term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx1 epoxide hydrolase 1 affects hydrolysis ISO EPHX1 protein affects the hydrolysis of 8,9-epoxyeicosatrienoic acid CTD PMID:28975360 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 increases abundance ISO EPHX2 gene mutant form results in increased abundance of 8,9-epoxyeicosatrienoic acid CTD PMID:19896470 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        biochemical role 19281
          metabolite 19262
            EET 12
              8,9-EET 2
                (8R,9S)-EET 0
                (8S,9R)-EET 0
                8,9-epoxy-(5Z,11Z,14Z)-icosatrienoyl-CoA 0
                N-[(5Z,11Z,14Z)-8,9-epoxyicosatrienoyl]ethanolamine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        monocarboxylic acid 17406
                                          fatty acid 15844
                                            unsaturated fatty acid 922
                                              polyunsaturated fatty acid 663
                                                fatty acid 20:4 313
                                                  icosatetraenoic acid 313
                                                    icosa-5,8,11,14-tetraenoic acid 264
                                                      arachidonic acid 264
                                                        EET 12
                                                          8,9-EET 2
                                                            (8R,9S)-EET 0
                                                            (8S,9R)-EET 0
                                                            8,9-epoxy-(5Z,11Z,14Z)-icosatrienoyl-CoA 0
                                                            N-[(5Z,11Z,14Z)-8,9-epoxyicosatrienoyl]ethanolamine 0
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