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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-alpha-THDOC
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Accession:CHEBI:34461 term browser browse the term
Definition:A 21-hydroxy steroid that has formula C21H34O3.
Synonyms:related_synonym: 2-hydroxy-1-[(1S,2S,5R,7S,10R,11S,14S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]ethan-1-one;   3alpha,21-Dihydroxy-5alpha-pregnan-20-one;   3alpha,21-Dihydroxy-5beta-pregnan-20-one;   5alpha-THDOC;   Allotetrahydrodeoxycorticosterone;   Deoxycorticosterone-21-aminopropane;   Formula=C21H34O3;   InChI=1S/C21H34O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h13-18,22-23H,3-12H2,1-2H3/t13-,14+,15-,16-,17-,18+,20-,21-/m0/s1;   InChIKey=CYKYBWRSLLXBOW-GDYGHMJCSA-N;   SMILES=C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO;   Tetrahydro-11-deoxycorticosterone
 xref: CAS:567-02-2;   CAS:567-03-3;   HMDB:HMDB0000879;   KEGG:C13713
 xref_mesh: MESH:C009413
 xref: PMID:11804209;   PMID:12271438;   PMID:12628349;   PMID:1316648;   PMID:16959481;   PMID:2156398;   PMID:4644861;   PMID:5108103;   PMID:6249834;   PMID:8817726



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5-alpha-THDOC term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c1 aldo-keto reductase family 1, member C1 affects oxidation ISO AKR1C1 protein affects the oxidation of tetrahydrodeoxycorticosterone CTD PMID:12604236 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 affects oxidation ISO AKR1C2 protein affects the oxidation of tetrahydrodeoxycorticosterone CTD PMID:12604236 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta decreases expression EXP tetrahydrodeoxycorticosterone results in decreased expression of GABRD protein CTD PMID:16914187 NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20057
    chemical entity 20068
      molecular entity 20056
        polyatomic entity 19987
          heteroatomic molecular entity 19923
            hydroxides 19434
              organic hydroxy compound 19001
                hydroxy steroid 14098
                  21-hydroxy steroid 4799
                    5-alpha-THDOC 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20057
    subatomic particle 20056
      composite particle 20068
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19889
                        carbon atom 19894
                          organic molecular entity 19882
                            organic molecule 19830
                              organic cyclic compound 19603
                                organic polycyclic compound 17185
                                  steroid 14382
                                    hydroxy steroid 14098
                                      21-hydroxy steroid 4799
                                        5-alpha-THDOC 3
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