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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-octylphenol
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Accession:CHEBI:34432 term browser browse the term
Definition:A member of the class of phenols that is phenol which is substituted at the para- position by an octyl group.
Synonyms:related_synonym: 1-(p-hydroxyphenyl)octane;   4-n-octylphenol;   Formula=C14H22O;   InChI=1S/C14H22O/c1-2-3-4-5-6-7-8-13-9-11-14(15)12-10-13/h9-12,15H,2-8H2,1H3;   InChIKey=NTDQQZYCCIDJRK-UHFFFAOYSA-N;   SMILES=CCCCCCCCc1ccc(O)cc1;   p-octylphenol
 xref: CAS:1806-26-4;   KEGG:C14132
 xref_mesh: MESH:C080417
 xref: PMID:20980040;   PMID:22435736;   PMID:23435201;   PMID:23520882;   PMID:23562958;   PMID:23714150;   PMID:23818073;   PMID:23877625;   PMID:24209326;   Reaxys:2046736


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4-octylphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP 4-octylphenol binds to AFP protein CTD PMID:23013281, PMID:25349334 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Ar androgen receptor affects binding
multiple interactions
EXP
ISO
4-octylphenol binds to AR protein
4-octylphenol inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
CTD PMID:14565775, PMID:16169144 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO 4-octylphenol results in increased expression of B4GALT1 mRNA CTD PMID:14605097 NCBI chr 5:57,121,768...57,168,610
Ensembl chr 5:57,121,769...57,168,610
JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression ISO 4-octylphenol results in decreased expression of CDO1 mRNA CTD PMID:16223563 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO 4-octylphenol inhibits the reaction [Acetylcholine affects the activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:11711029 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO 4-octylphenol inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:11711029 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO 4-octylphenol inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:11711029 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO 4-octylphenol inhibits the reaction [Acetylcholine affects the activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:11711029 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP 4-octylphenol results in decreased expression of CYP17A1 protein CTD PMID:9361775 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Esr1 estrogen receptor 1 increases activity
affects binding
affects localization
multiple interactions
ISO
EXP
4-octylphenol results in increased activity of ESR1 protein
4-octylphenol binds to ESR1 protein
4-octylphenol affects the localization of ESR1 protein
[4-octylphenol co-treated with ESR1 protein] results in increased expression of LTF mRNA
CTD PMID:18028983, PMID:19913605, PMID:20950447, PMID:21783566 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding
affects localization
ISO [4-octylphenol co-treated with ESR2 protein] results in increased expression of LTF mRNA
4-octylphenol binds to ESR2 protein
4-octylphenol affects the localization of ESR2 protein
CTD PMID:19913605, PMID:20950447, PMID:21783566 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fam102a family with sequence similarity 102, member A increases expression ISO 4-octylphenol results in increased expression of FAM102A mRNA CTD PMID:14605097 NCBI chr 3:11,554,084...11,586,315
Ensembl chr 3:11,554,457...11,586,303
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO 4-octylphenol results in increased expression of FOS mRNA; 4-octylphenol results in increased expression of FOS protein CTD PMID:24308608 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gh1 growth hormone 1 increases expression
multiple interactions
increases secretion
EXP 4-octylphenol results in increased expression of GH1 mRNA
fulvestrant inhibits the reaction [4-octylphenol results in increased expression of GH1 mRNA]; fulvestrant inhibits the reaction [4-octylphenol results in increased secretion of GH1 protein]
CTD PMID:19463694 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO 4-octylphenol affects the reaction [HRAS protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene] CTD PMID:12117780 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO 4-octylphenol results in decreased activity of HSD11B2 protein CTD PMID:16184081 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO 4-octylphenol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions
ISO 4-octylphenol results in decreased expression of IL10
4-octylphenol results in decreased expression of and results in decreased secretion of IL10 protein
CTD PMID:20056579, PMID:24039973 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Kmt2a lysine methyltransferase 2A increases expression ISO 4-octylphenol results in increased expression of KMT2A protein CTD PMID:20056579 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G Ltf lactotransferrin multiple interactions ISO [4-octylphenol co-treated with ESR1 protein] results in increased expression of LTF mRNA; [4-octylphenol co-treated with ESR2 protein] results in increased expression of LTF mRNA CTD PMID:21783566 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
4-octylphenol inhibits the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; 4-octylphenol inhibits the reaction [Estriol results in increased phosphorylation of MAPK1 protein]; 4-octylphenol inhibits the reaction [Estrone results in increased phosphorylation of MAPK1 protein]
4-octylphenol results in increased phosphorylation of MAPK1 protein
4-octylphenol analog affects the reaction [Estradiol affects the phosphorylation of MAPK1 protein]; 4-octylphenol analog affects the reaction [Estriol affects the phosphorylation of MAPK1 protein]; 4-octylphenol analog affects the reaction [Estrone affects the phosphorylation of MAPK1 protein]
CTD PMID:19463694, PMID:20870566, PMID:20950447 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
4-octylphenol inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; 4-octylphenol inhibits the reaction [Estriol results in increased phosphorylation of MAPK3 protein]; 4-octylphenol inhibits the reaction [Estrone results in increased phosphorylation of MAPK3 protein]
4-octylphenol results in increased phosphorylation of MAPK3 protein
4-octylphenol analog affects the reaction [Estradiol affects the phosphorylation of MAPK3 protein]; 4-octylphenol analog affects the reaction [Estriol affects the phosphorylation of MAPK3 protein]; 4-octylphenol analog affects the reaction [Estrone affects the phosphorylation of MAPK3 protein]
CTD PMID:19463694, PMID:20870566, PMID:20950447 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO 4-octylphenol inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects activity ISO 4-octylphenol affects the activity of NR1I2 protein CTD PMID:20024649 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases activity
ISO 4-octylphenol binds to and results in decreased activity of NR1I3 protein alternative form
4-octylphenol results in increased activity of NR1I3 protein
CTD PMID:20869355, PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta multiple interactions
decreases activity
EXP 4-octylphenol inhibits the reaction [Triiodothyronine, Reverse binds to P4HB protein]
4-octylphenol results in decreased activity of P4HB protein
CTD PMID:16617682 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Papss1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 decreases expression ISO 4-octylphenol results in decreased expression of PAPSS1 mRNA CTD PMID:16223563 NCBI chr 2:236,605,695...236,680,772
Ensembl chr 2:236,605,695...236,680,772
JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 decreases expression ISO 4-octylphenol results in decreased expression of PAPSS2 mRNA CTD PMID:16223563 NCBI chr 1:251,145,264...251,230,716
Ensembl chr 1:251,145,253...251,230,715
JBrowse link
G Pdzk1 PDZ domain containing 1 increases expression ISO 4-octylphenol results in increased expression of PDZK1 mRNA CTD PMID:14605097 NCBI chr 2:198,965,685...198,999,323
Ensembl chr 2:198,965,685...198,999,323
JBrowse link
G Prl prolactin multiple interactions
increases secretion
increases expression
ISO
EXP
4-octylphenol affects the reaction [Estriol results in increased secretion of PRL protein]; 4-octylphenol affects the reaction [Estrone results in increased secretion of PRL protein]; 4-octylphenol inhibits the reaction [Estradiol results in increased secretion of PRL protein]
fulvestrant inhibits the reaction [4-octylphenol results in increased expression of PRL mRNA]; fulvestrant inhibits the reaction [4-octylphenol results in increased secretion of PRL protein]
CTD PMID:19463694, PMID:20950447 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO 4-octylphenol binds to SHBG protein CTD PMID:25349334 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Skil SKI-like proto-oncogene increases expression ISO 4-octylphenol results in increased expression of SKIL protein CTD PMID:24308608 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases metabolic processing ISO SULT1A1 protein results in increased metabolism of 4-octylphenol CTD PMID:10623578 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 increases metabolic processing ISO SULT1B1 protein results in increased metabolism of 4-octylphenol CTD PMID:10623578 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases metabolic processing ISO SULT2A1 protein results in increased metabolism of 4-octylphenol CTD PMID:10623578 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Suox sulfite oxidase decreases expression ISO 4-octylphenol results in decreased expression of SUOX mRNA CTD PMID:16223563 NCBI chr 7:3,098,228...3,102,179
Ensembl chr 7:3,098,245...3,102,142
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO 4-octylphenol results in increased expression of TNF
4-octylphenol results in increased expression of and results in increased secretion of TNF protein; anacardic acid inhibits the reaction [4-octylphenol results in increased expression of and results in increased secretion of TNF protein]
CTD PMID:20056579, PMID:24039973 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Wdr5 WD repeat domain 5 increases expression ISO 4-octylphenol results in increased expression of WDR5 protein CTD PMID:20056579 NCBI chr 3:6,061,892...6,080,724
Ensembl chr 3:6,061,940...6,080,680
JBrowse link
Nonidet P-40 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arnt aryl hydrocarbon receptor nuclear translocator decreases expression ISO Nonidet P-40 results in decreased expression of ARNT mRNA CTD PMID:26552463 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Nonidet P-40 results in increased expression of ATF4 mRNA CTD PMID:26552463 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Nonidet P-40 results in increased expression of ATF6 mRNA CTD PMID:26552463 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atf6b activating transcription factor 6 beta increases expression ISO Nonidet P-40 results in increased expression of ATF6B mRNA CTD PMID:26552463 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283
JBrowse link
G Atg12 autophagy related 12 increases expression ISO Nonidet P-40 results in increased expression of ATG12 mRNA CTD PMID:26552463 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atg5 autophagy related 5 decreases expression ISO Nonidet P-40 results in decreased expression of ATG5 mRNA CTD PMID:26552463 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atg7 autophagy related 7 decreases expression ISO Nonidet P-40 results in decreased expression of ATG7 mRNA CTD PMID:26552463 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO Nonidet P-40 results in decreased expression of ATR mRNA CTD PMID:26552463 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Nonidet P-40 results in increased expression of BBC3 mRNA CTD PMID:26552463 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Becn1 beclin 1 increases expression ISO Nonidet P-40 results in increased expression of BECN1 mRNA CTD PMID:26552463 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO Nonidet P-40 results in increased expression of BID mRNA CTD PMID:26552463 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Nonidet P-40 results in increased expression of BNIP3L mRNA CTD PMID:26552463 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Ca9 carbonic anhydrase 9 decreases expression ISO Nonidet P-40 results in decreased expression of CA9 mRNA CTD PMID:26552463 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Calr calreticulin decreases expression ISO Nonidet P-40 results in decreased expression of CALR mRNA CTD PMID:26552463 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Casp1 caspase 1 decreases expression ISO Nonidet P-40 results in decreased expression of CASP1 mRNA CTD PMID:26552463 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Nonidet P-40 results in increased expression of CCL2 mRNA CTD PMID:26552463 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Nonidet P-40 results in increased expression of CDKN1A mRNA CTD PMID:26552463 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO Nonidet P-40 results in increased expression of CHEK2 mRNA CTD PMID:26552463 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Crp C-reactive protein increases expression ISO Nonidet P-40 results in increased expression of CRP mRNA CTD PMID:26552463 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Ddb2 damage specific DNA binding protein 2 decreases expression ISO Nonidet P-40 results in decreased expression of DDB2 mRNA CTD PMID:26552463 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Nonidet P-40 results in increased expression of DDIT3 mRNA CTD PMID:26552463 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression ISO Nonidet P-40 results in increased expression of DNAJC3 mRNA CTD PMID:26552463 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Epo erythropoietin decreases expression ISO Nonidet P-40 results in decreased expression of EPO mRNA CTD PMID:26552463 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Nonidet P-40 results in increased expression of GADD45A mRNA CTD PMID:26552463 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Nonidet P-40 results in decreased expression of GCLC mRNA CTD PMID:26552463 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Nonidet P-40 results in increased expression of GCLM mRNA CTD PMID:26552463 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO Nonidet P-40 results in decreased expression of GRB2 mRNA CTD PMID:26552463 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Nonidet P-40 results in increased expression of HMOX1 mRNA CTD PMID:26552463 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Nonidet P-40 results in increased expression of HSP90AA1 mRNA CTD PMID:26552463 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression ISO Nonidet P-40 results in increased expression of HSPA4 mRNA CTD PMID:26552463 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression ISO Nonidet P-40 results in increased expression of HSPA4L mRNA CTD PMID:26552463 NCBI chr 2:127,625,737...127,682,864
Ensembl chr 2:127,625,683...127,677,503
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Nonidet P-40 results in decreased expression of HSPA5 mRNA CTD PMID:26552463 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hus1 HUS1 checkpoint clamp component increases expression ISO Nonidet P-40 results in increased expression of HUS1 mRNA CTD PMID:26552463 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825
JBrowse link
G Ifng interferon gamma decreases expression ISO Nonidet P-40 results in decreased expression of IFNG mRNA CTD PMID:26552463 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Nonidet P-40 results in decreased expression of IL1A mRNA CTD PMID:26552463 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il6 interleukin 6 increases expression ISO Nonidet P-40 results in increased expression of IL6 mRNA CTD PMID:26552463 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO Nonidet P-40 results in decreased expression of LDHA mRNA CTD PMID:26552463 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Nonidet P-40 results in increased expression of MCL1 mRNA CTD PMID:26552463 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO Nonidet P-40 results in decreased expression of MMP9 mRNA CTD PMID:26552463 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease increases expression ISO Nonidet P-40 results in increased expression of MRE11A mRNA CTD PMID:26552463 NCBI chr 8:13,304,355...13,350,329
Ensembl chr 8:13,305,152...13,352,489
JBrowse link
G Nbn nibrin increases expression ISO Nonidet P-40 results in increased expression of NBN mRNA CTD PMID:26552463 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Nonidet P-40 results in increased expression of NQO1 mRNA CTD PMID:26552463 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Nonidet P-40 results in decreased expression of PARP1 mRNA CTD PMID:26552463 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Rad17 RAD17 checkpoint clamp loader component increases expression ISO Nonidet P-40 results in increased expression of RAD17 mRNA CTD PMID:26552463 NCBI chr 2:30,634,353...30,664,618
Ensembl chr 2:30,634,354...30,664,163
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO Nonidet P-40 results in decreased expression of RAD51 mRNA CTD PMID:26552463 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad9a RAD9 checkpoint clamp component A increases expression ISO Nonidet P-40 results in increased expression of RAD9A mRNA CTD PMID:26552463 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451
JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Nonidet P-40 results in decreased expression of SERPINE1 mRNA CTD PMID:26552463 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Nonidet P-40 results in increased expression of SLC2A1 mRNA CTD PMID:26552463 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO Nonidet P-40 results in decreased expression of SQSTM1 mRNA CTD PMID:26552463 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Nonidet P-40 results in decreased expression of TLR4 mRNA CTD PMID:26552463 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b decreases expression ISO Nonidet P-40 results in decreased expression of TNFRSF10A mRNA CTD PMID:26552463 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO Nonidet P-40 results in decreased expression of TNFRSF1A mRNA CTD PMID:26552463 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Nonidet P-40 results in decreased expression of TP53 mRNA CTD PMID:26552463 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Txn1 thioredoxin 1 decreases expression ISO Nonidet P-40 results in decreased expression of TXN mRNA CTD PMID:26552463 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Nonidet P-40 results in increased expression of TXNRD1 mRNA CTD PMID:26552463 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 decreases expression ISO Nonidet P-40 results in decreased expression of ULK1 mRNA CTD PMID:26552463 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Nonidet P-40 results in decreased expression of VEGFA mRNA CTD PMID:26552463 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor decreases expression ISO Nonidet P-40 results in decreased expression of XPC mRNA CTD PMID:26552463 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      chemical role 19283
        emulsifier 4333
          surfactant 4333
            4-octylphenol 96
              Nonidet P-40 58
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic aromatic compound 19146
                                  phenols 18144
                                    4-octylphenol 96
                                      Nonidet P-40 58
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.