CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 3-methylcholanthrene
Accession: CHEBI:34342
browse the term
Definition: A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Synonyms: exact_synonym: 3-methyl-1,2-dihydrocyclopenta[ij]tetraphene
related_synonym: 1,2-Dihydro-3-methylbenz(j)aceanthrylene; 20-MC; 20-Methylcholanthrene; 3-MC; 3-MCA; 3-methyl-1,2-dihydrobenzo[j]aceanthrylene; Formula=C21H16; InChI=1S/C21H16/c1-13-6-7-15-12-20-17-5-3-2-4-14(17)8-9-18(20)19-11-10-16(13)21(15)19/h2-9,12H,10-11H2,1H3; InChIKey=PPQNQXQZIWHJRB-UHFFFAOYSA-N; MC; MCA; Methylcholanthrene; SMILES=Cc1ccc2cc3c(ccc4ccccc34)c3CCc1c23
xref: Beilstein:1913890; CAS:56-49-5; KEGG:C14470; LINCS:LSM-5711
xref_mesh: MESH:D008748
xref: PMID:11922910; PMID:16359657; PMID:24658119; PMID:26076008; PMID:7561049; Reaxys:1913890; Wikipedia:Methylcholanthrene
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ABCA1
ATP binding cassette subfamily A member 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of ABCA1 mRNA
CTD
PMID:20713471
NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
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ABCB1
ATP binding cassette subfamily B member 1
increases expression
ISO
Methylcholanthrene results in increased expression of ABCB1 mRNA; Methylcholanthrene results in increased expression of ABCB1A mRNA
CTD
PMID:11096091 PMID:27160211
NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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ABCB4
ATP binding cassette subfamily B member 4
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of ABCB4 mRNA
CTD
PMID:25926378
NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435
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ABCB6
ATP binding cassette subfamily B member 6 (LAN blood group)
increases expression
EXP ISO
Methylcholanthrene results in increased expression of ABCB6 mRNA
CTD
PMID:22761424
NCBI chr 2:219,209,772...219,218,958
Ensembl chr 2:219,209,772...219,218,994
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ABCC3
ATP binding cassette subfamily C member 3
increases expression
ISO
Methylcholanthrene results in increased expression of ABCC3 mRNA
CTD
PMID:19118567
NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
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ABCC4
ATP binding cassette subfamily C member 4 (PEL blood group)
increases expression
EXP
Methylcholanthrene results in increased expression of ABCC4 mRNA; Methylcholanthrene results in increased expression of ABCC4 protein
CTD
PMID:20395535
NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475
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ABCG2
ATP binding cassette subfamily G member 2 (JR blood group)
multiple interactions affects response to substance increases expression
EXP
AHR protein affects the reaction [Methylcholanthrene results in increased expression of ABCG2 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to ABCG2 5' UTR] ABCG2 5' UTR affects the susceptibility to Methylcholanthrene Methylcholanthrene results in increased expression of ABCG2; Methylcholanthrene results in increased expression of ABCG2 mRNA; Methylcholanthrene results in increased expression of ABCG2 mRNA alternative form; Methylcholanthrene results in increased expression of ABCG2 protein
CTD
PMID:20804740 PMID:23081912
NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
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ABI3BP
ABI family member 3 binding protein
decreases expression
ISO
Methylcholanthrene results in decreased expression of ABI3BP mRNA
CTD
PMID:20713471
NCBI chr 3:100,749,156...100,993,421
Ensembl chr 3:100,749,156...100,993,515
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ACOX2
acyl-CoA oxidase 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ACOX2 promoter]
CTD
PMID:20348232
NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283
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ACSL4
acyl-CoA synthetase long chain family member 4
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ACSL4 promoter]
CTD
PMID:20348232
NCBI chr X:109,641,335...109,733,257
Ensembl chr X:109,624,244...109,733,403
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ACTA1
actin alpha 1, skeletal muscle
decreases expression
ISO
Methylcholanthrene results in decreased expression of ACTA1 mRNA
CTD
PMID:29554273
NCBI chr 1:229,431,245...229,434,094
Ensembl chr 1:229,430,365...229,434,104
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ACTA2
actin alpha 2, smooth muscle
decreases expression
ISO
Methylcholanthrene results in decreased expression of ACTA2 mRNA
CTD
PMID:20713471
NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339
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ADAM8
ADAM metallopeptidase domain 8
increases expression
ISO
Methylcholanthrene results in increased expression of ADAM8 mRNA
CTD
PMID:20713471
NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868
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ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
decreases acetylation increases methylation increases expression multiple interactions
ISO
Methylcholanthrene results in decreased acetylation of ADAMTS1 promoter Methylcholanthrene results in increased methylation of ADAMTS1 promoter Methylcholanthrene results in increased expression of ADAMTS1 mRNA [alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of ADAMTS1 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of ADAMTS1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ADAMTS1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of ADAMTS1 promoter]
CTD
PMID:29094188
NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409
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ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif 12
decreases expression
ISO
Methylcholanthrene results in decreased expression of ADAMTS12 mRNA
CTD
PMID:20713471
NCBI chr 5:33,523,535...33,891,990
Ensembl chr 5:33,523,535...33,892,019
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ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of ADAMTS2 mRNA
CTD
PMID:20713471
NCBI chr 5:179,110,853...179,345,461
Ensembl chr 5:179,110,853...179,345,461
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ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4
increases expression
ISO
Methylcholanthrene results in increased expression of ADAMTS4 mRNA
CTD
PMID:20713471
NCBI chr 1:161,184,302...161,199,054
Ensembl chr 1:161,184,302...161,199,054
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ADCY7
adenylate cyclase 7
increases expression
ISO
Methylcholanthrene results in increased expression of ADCY7 mRNA
CTD
PMID:20713471 PMID:29554273
NCBI chr16:50,244,699...50,318,135
Ensembl chr16:50,246,137...50,318,135
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ADGRF1
adhesion G protein-coupled receptor F1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ADGRF1 promoter]
CTD
PMID:20348232
NCBI chr 6:46,997,708...47,042,332
Ensembl chr 6:46,997,708...47,042,350
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ADGRG5
adhesion G protein-coupled receptor G5
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of ADGRG5 mRNA; [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of ADGRG5 mRNA
CTD
PMID:25926378
NCBI chr16:57,529,073...57,577,189
Ensembl chr16:57,542,643...57,591,681
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ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
decreases expression
EXP
Methylcholanthrene results in decreased expression of ADH1B mRNA
CTD
PMID:27055685
NCBI chr 4:99,304,971...99,321,401
Ensembl chr 4:99,304,971...99,321,401
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ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
decreases expression
EXP
Methylcholanthrene results in decreased expression of ADH4 mRNA
CTD
PMID:27055685
NCBI chr 4:99,123,658...99,144,297
Ensembl chr 4:99,123,657...99,157,792
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ADH6
alcohol dehydrogenase 6 (class V)
decreases expression
EXP
Methylcholanthrene results in decreased expression of ADH6 mRNA
CTD
PMID:27055685
NCBI chr 4:99,202,639...99,219,246
Ensembl chr 4:99,202,638...99,219,537
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ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
increases expression
ISO
Methylcholanthrene results in increased expression of ADH7 mRNA
CTD
PMID:20713471
NCBI chr 4:99,412,263...99,435,342
Ensembl chr 4:99,412,261...99,435,510
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ADORA2A
adenosine A2a receptor
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA2A mRNA
CTD
PMID:23519560
NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
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ADORA3
adenosine A3 receptor
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA3 mRNA
CTD
PMID:23519560
NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
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ADRA2A
adrenoceptor alpha 2A
multiple interactions
EXP ISO
Methylcholanthrene promotes the reaction [AHR protein binds to ADRA2A promoter] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADRA2A mRNA
CTD
PMID:20348232 PMID:23519560
NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
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AGR2
anterior gradient 2, protein disulphide isomerase family member
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to AGR2 promoter]
CTD
PMID:20348232
NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433
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AHR
aryl hydrocarbon receptor
increases response to substance increases expression decreases expression affects binding multiple interactions increases activity increases localization affects response to substance increases degradation affects localization
EXP ISO
AHR protein results in increased susceptibility to Methylcholanthrene; AHR results in increased susceptibility to Methylcholanthrene Methylcholanthrene results in increased expression of AHR mRNA Methylcholanthrene results in decreased expression of AHR protein Methylcholanthrene binds to AHR protein [Genistein co-treated with Methylcholanthrene] affects the activity of AHR protein; AHR protein affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter] [Methylcholanthrene binds to and affects the localization of AHR protein] promotes the reaction [[AHR protein binds to CYP1A1 enhancer] which results in increased expression of CYP1A1 mRNA]; [Methylcholanthrene binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA; AHR affects the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; AHR affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR gene mutant form inhibits the reaction [Methylcholanthrene results in decreased expression of CYP3A11 mRNA]; AHR protein affects the reaction [Methylcholanthrene affects the expression of CYP1A1 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of FMO3 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of XDH protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased activity of and results in increased localization of AHR protein]; CTNNB1 protein affects the reaction [[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; Curcumin inhibits the reaction [Methylcholanthrene binds to AHR protein]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Methylcholanthrene binds to and affects the localization of AHR protein; Methylcholanthrene binds to and results in increased activity of AHR protein; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [SRC protein binds to AHR protein]]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene results in increased activity of and results in increased localization of AHR protein; omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; Raloxifene Hydrochloride inhibits the reaction [Methylcholanthrene binds to AHR protein] Methylcholanthrene results in increased localization of AHR protein AHR affects the susceptibility to Methylcholanthrene Methylcholanthrene results in increased degradation of AHR protein Methylcholanthrene results in increased expression of AHR protein [AHR gene mutant form binds to ARNT protein] which results in decreased susceptibility to Methylcholanthrene; [chrysin co-treated with Methylcholanthrene] affects the activity of AHR protein; [Genistein co-treated with Methylcholanthrene] affects the activity of AHR protein; [Methylcholanthrene co-treated with Oxygen deficiency] results in increased expression of AHR mRNA; [Methylcholanthrene co-treated with pirinixic acid] results in increased expression of AHR protein; [Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of IL1B mRNA; [Quercetin co-treated with Methylcholanthrene] affects the activity of AHR protein; AHR gene mutant form inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of ABCG2 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of CYP3A5 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; Methylcholanthrene binds to and results in increased activity of AHR protein; Methylcholanthrene binds to and results in increased activity of AHR protein polymorphism; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to ABCG2 5' UTR]; Methylcholanthrene promotes the reaction [AHR protein binds to ACOX2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ACSL4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ADGRF1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ADRA2A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to AGR2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to AKAP13 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ANGPTL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ANKRD13C promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ANKRD30B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP22 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP35 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP44 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARL3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARMC12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BAMBI promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BBX promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BCL6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BPIFA2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BRCA1 protein]; Methylcholanthrene promotes the reaction [AHR protein binds to BRWD1-AS2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to C16ORF74 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF19 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF36 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CA12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CA8 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CACNA1B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CALB2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CAST promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCDC144NL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCDC57 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCDC6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCN5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CD55 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CEACAM3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CENPL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CEP70 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CFAP61 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CHPT1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CHRDL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CILK1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CISD1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CLDN17 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CLK3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CLPSL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to COLCA1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to COX4I1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CRKL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CTNNA1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CUEDC1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYB5B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP2A7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DEGS1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DIAPH1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DTNA promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DUSP14 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to EHD3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to EPS15 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ERCC6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to EXOSC9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to FOXN1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to FREM2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GDPD4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GPHB5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GREB1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GRIK4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GSDMC promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to H2BC1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to H2BC21 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HCRTR2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HDAC11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HOXC11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HSBP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IDH2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IER3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IGFBPL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to INHBC promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IRF2BPL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ISOC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ITPR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to JPH1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KATNAL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KCTD16 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KCTD3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KIR2DL4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KLF9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KRT75 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LGALS8 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LGI1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LIF promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LIMA1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LINC00173 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LRP11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LSM5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LY6E promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MAPKAP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MBNL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MED13L promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MESP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MGST2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MIDEAS promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MLLT6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MLPH promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MPI promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MRTFB promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MS4A7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MSMB promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MTCL3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MYOF promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MYOM2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NBPF10 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NBPF3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NDST1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NELFCD promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NFE2L2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NMRAL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NXT2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to OSBPL10 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to OTUB2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PAXBP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PCOLCE2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PDCD4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PHACTR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PIGP promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PIK3R1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PLEKHA6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to POGZ promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to POTEB promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PPIAL4A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PRKAB1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PRKAB2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PRPS1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PSG5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PSG9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PWWP3A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RABL2A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RALGAPA2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RANBP2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBBP7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBM24 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBMS2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBSN promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RERG promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RFFL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RGPD5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RGPD6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RGS3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RHOBTB1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RHOH promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RPL11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RTN3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RYR3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to S100P promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SAMD12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SCN3B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SIK3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLC16A6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLC22A23 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLC44A1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLU7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SMAP2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SMARCE1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SNAPIN promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SOCS7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SORL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SOS1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SPON2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SPRED1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SPTLC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SS18 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to STARD13 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to STAT5B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SWSAP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SYCP2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SYT12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TBL1XR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TEAD4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to THBS2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to THEM5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TIPARP promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM116 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM30A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM45B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM97 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMTC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TNK2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRERF1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRIM39 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRIM55 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRIM72 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRPV4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TTC3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to UBE2E1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to UMODL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VEZT promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VIPR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VSTM1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VWCE promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to WBP1L promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to WDR26 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to WEE1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZBTB4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZCCHC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZMAT3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZMIZ1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF281 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF552 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF587 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF695 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF710 promoter]; Methylcholanthrene promotes the reaction [Nicardipine results in increased activity of AHR protein]; Methylcholanthrene results in increased activity of and results in increased degradation of AHR protein; Nicardipine promotes the reaction [Methylcholanthrene results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; Resveratrol inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein] Methylcholanthrene affects the localization of AHR protein
CTD
PMID:1650214 PMID:1654865 PMID:1658612 PMID:1846074 PMID:2154949 PMID:2833345 PMID:3005314 PMID:3024361 PMID:3040233 PMID:3402044 PMID:6301823 PMID:6322977 PMID:6749129 PMID:7140758 PMID:8163516 PMID:8163517 PMID:8937476 PMID:11158718 PMID:11243847 PMID:11285323 PMID:11339718 PMID:11549291 PMID:11768231 PMID:12117779 PMID:12490138 PMID:12700417 PMID:12825898 PMID:14993811 PMID:15297030 PMID:15585370 PMID:15860653 PMID:16109480 PMID:16137816 PMID:16359657 PMID:16489053 PMID:16829687 PMID:17069994 PMID:17880909 PMID:18022818 PMID:18259752 PMID:18835618 PMID:19286049 PMID:19853001 PMID:19951702 PMID:20067464 PMID:20171196 PMID:20348232 PMID:20540524 PMID:20570689 PMID:20570779 PMID:20804740 PMID:20881032 PMID:21250977 PMID:21292640 PMID:21498875 PMID:21666223 PMID:21756928 PMID:23273579 PMID:23712962 PMID:23846873 PMID:23994556 PMID:24481452 PMID:24486526 PMID:26006071 PMID:27644595 PMID:28887089 PMID:29094188 PMID:33408298 PMID:33811995 More...
NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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AHRR
aryl hydrocarbon receptor repressor
multiple interactions increases expression
ISO EXP
[Tetradecanoylphorbol Acetate co-treated with Methylcholanthrene] results in increased expression of AHRR mRNA Methylcholanthrene results in increased expression of AHRR mRNA
CTD
PMID:9887096 PMID:11423533 PMID:12655030 PMID:14672759
NCBI chr 5:321,714...438,285
Ensembl chr 5:321,714...438,291
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AKAP13
A-kinase anchoring protein 13
decreases expression multiple interactions
ISO EXP
Methylcholanthrene results in decreased expression of AKAP13 mRNA Methylcholanthrene promotes the reaction [AHR protein binds to AKAP13 promoter]
CTD
PMID:20348232 PMID:20713471
NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358
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AKR1A1
aldo-keto reductase family 1 member A1
increases expression
EXP
Methylcholanthrene results in increased expression of AKR1A1 mRNA
CTD
PMID:9973208
NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049
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AKR1C1
aldo-keto reductase family 1 member C1
increases expression
EXP
Methylcholanthrene results in increased expression of AKR1C1 mRNA
CTD
PMID:9973208
NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283
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AKT1
AKT serine/threonine kinase 1
decreases acetylation increases expression multiple interactions
ISO
Methylcholanthrene results in decreased acetylation of AKT1 promoter Methylcholanthrene results in increased expression of AKT1 mRNA alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of AKT1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of AKT1 mRNA]
CTD
PMID:29094188
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
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ALCAM
activated leukocyte cell adhesion molecule
increases expression
ISO
Methylcholanthrene results in increased expression of ALCAM mRNA
CTD
PMID:20713471
NCBI chr 3:105,366,909...105,576,900
Ensembl chr 3:105,366,909...105,576,900
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ALDH3A1
aldehyde dehydrogenase 3 family member A1
increases expression
ISO EXP
Methylcholanthrene results in increased expression of ALDH3A1 mRNA
CTD
PMID:1416978 PMID:20713471 PMID:28601433
NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943
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ANGPTL2
angiopoietin like 2
increases expression multiple interactions
ISO EXP
Methylcholanthrene results in increased expression of ANGPTL2 mRNA Methylcholanthrene promotes the reaction [AHR protein binds to ANGPTL2 promoter]
CTD
PMID:20348232 PMID:20713471
NCBI chr 9:127,087,348...127,122,635
Ensembl chr 9:127,087,348...127,122,635
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ANK2
ankyrin 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of ANK2 mRNA
CTD
PMID:20713471
NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
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ANKH
ANKH inorganic pyrophosphate transport regulator
increases expression
ISO
Methylcholanthrene results in increased expression of ANK mRNA
CTD
PMID:20713471
NCBI chr 5:14,704,800...14,871,778
Ensembl chr 5:14,704,800...14,871,778
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ANKRD13C
ankyrin repeat domain 13C
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ANKRD13C promoter]
CTD
PMID:20348232
NCBI chr 1:70,258,999...70,354,722
Ensembl chr 1:70,258,999...70,354,734
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ANKRD30B
ankyrin repeat domain 30B
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ANKRD30B promoter]
CTD
PMID:20348232
NCBI chr18:14,748,172...14,941,135
Ensembl chr18:14,728,272...14,854,667
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ANLN
anillin, actin binding protein
increases expression
ISO
Methylcholanthrene results in increased expression of ANLN mRNA
CTD
PMID:20713471
NCBI chr 7:36,389,862...36,453,791
Ensembl chr 7:36,389,821...36,453,791
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ANXA8
annexin A8
increases expression
ISO
Methylcholanthrene results in increased expression of ANXA8 mRNA
CTD
PMID:20713471
NCBI chr10:47,467,993...47,991,796
Ensembl chr10:47,460,162...47,484,158
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APAF1
apoptotic peptidase activating factor 1
increases expression
ISO
Methylcholanthrene results in increased expression of APAF1 mRNA
CTD
PMID:23273579
NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433
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APCDD1
APC down-regulated 1
increases expression
ISO
Methylcholanthrene results in increased expression of APCDD1 mRNA
CTD
PMID:20713471
NCBI chr18:10,454,635...10,489,949
Ensembl chr18:10,454,635...10,489,949
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APOA4
apolipoprotein A4
decreases expression
ISO
Methylcholanthrene results in decreased expression of APOA4 mRNA
CTD
PMID:11328961
NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
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APOC1
apolipoprotein C1
decreases expression
ISO
Methylcholanthrene results in decreased expression of APOC1 mRNA
CTD
PMID:11328961
NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349
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APOD
apolipoprotein D
decreases expression
ISO
Methylcholanthrene results in decreased expression of APOD mRNA
CTD
PMID:20713471
NCBI chr 3:195,568,705...195,583,940
Ensembl chr 3:195,568,705...195,584,033
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AQP5
aquaporin 5
increases expression
ISO
Methylcholanthrene results in increased expression of AQP5 mRNA
CTD
PMID:20713471 PMID:26372666
NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682
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AREG
amphiregulin
increases expression
EXP ISO
Methylcholanthrene results in increased expression of AREG mRNA
CTD
PMID:16257430 PMID:26372666
NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
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ARHGAP11A
Rho GTPase activating protein 11A
increases expression
ISO
Methylcholanthrene results in increased expression of ARHGAP11A mRNA
CTD
PMID:20713471
NCBI chr15:32,615,144...32,639,941
Ensembl chr15:32,615,144...32,639,941
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ARHGAP22
Rho GTPase activating protein 22
increases expression multiple interactions
ISO EXP
Methylcholanthrene results in increased expression of ARHGAP22 mRNA Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP22 promoter]
CTD
PMID:20348232 PMID:20713471
NCBI chr10:48,429,831...48,656,265
Ensembl chr10:48,446,036...48,656,265
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ARHGAP35
Rho GTPase activating protein 35
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP35 promoter]
CTD
PMID:20348232
NCBI chr19:46,860,997...47,005,077
Ensembl chr19:46,860,997...47,005,077
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ARHGAP44
Rho GTPase activating protein 44
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP44 promoter]
CTD
PMID:20348232
NCBI chr17:12,789,498...12,991,643
Ensembl chr17:12,789,498...12,991,643
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ARL3
ADP ribosylation factor like GTPase 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ARL3 promoter]
CTD
PMID:20348232
NCBI chr10:102,673,731...102,714,397
Ensembl chr10:102,673,731...102,714,397
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ARL6IP5
ADP ribosylation factor like GTPase 6 interacting protein 5
increases expression
ISO
Methylcholanthrene results in increased expression of ARL6IP5 mRNA
CTD
PMID:20713471
NCBI chr 3:69,084,937...69,106,092
Ensembl chr 3:69,084,937...69,106,092
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ARMC12
armadillo repeat containing 12
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ARMC12 promoter]
CTD
PMID:20348232
NCBI chr 6:35,731,524...35,749,079
Ensembl chr 6:35,737,032...35,749,079
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ARNT
aryl hydrocarbon receptor nuclear translocator
multiple interactions increases expression increases localization
EXP ISO
[AHR gene mutant form binds to ARNT protein] which results in decreased susceptibility to Methylcholanthrene; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [ARNT protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to SORL1 promoter] Methylcholanthrene results in increased expression of ARNT mRNA Methylcholanthrene results in increased localization of ARNT protein Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]
CTD
PMID:11768231 PMID:19951702 PMID:20348232 PMID:20570689 PMID:21756928 PMID:23273579 PMID:24486526 More...
NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708
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ARRB1
arrestin beta 1
increases expression
ISO
Methylcholanthrene results in increased expression of ARRB1 mRNA
CTD
PMID:29554273
NCBI chr11:75,260,122...75,351,661
Ensembl chr11:75,260,122...75,351,705
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ART3
ADP-ribosyltransferase 3 (inactive)
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ART3 mRNA
CTD
PMID:23519560
NCBI chr 4:76,011,190...76,112,786
Ensembl chr 4:76,011,184...76,114,048
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ASCL1
achaete-scute family bHLH transcription factor 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of ASCL1 mRNA
CTD
PMID:25926378
NCBI chr12:102,957,674...102,960,513
Ensembl chr12:102,957,674...102,960,513
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ASF1B
anti-silencing function 1B histone chaperone
increases expression
ISO
Methylcholanthrene results in increased expression of ASF1B mRNA
CTD
PMID:20713471
NCBI chr19:14,119,512...14,136,589
Ensembl chr19:14,119,512...14,136,613
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ASIC1
acid sensing ion channel subunit 1
increases expression
ISO
Methylcholanthrene results in increased expression of ASIC1 mRNA
CTD
PMID:20713471
NCBI chr12:50,057,596...50,083,622
Ensembl chr12:50,057,548...50,083,611
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ASPM
assembly factor for spindle microtubules
increases expression
ISO
Methylcholanthrene results in increased expression of ASPM mRNA
CTD
PMID:20713471
NCBI chr 1:197,084,127...197,146,669
Ensembl chr 1:197,084,121...197,146,694
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ASPN
asporin
decreases expression
ISO
Methylcholanthrene results in decreased expression of ASPN mRNA
CTD
PMID:20713471
NCBI chr 9:92,456,205...92,482,506
Ensembl chr 9:92,456,205...92,482,506
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ATAD2
ATPase family AAA domain containing 2
increases expression
ISO
Methylcholanthrene results in increased expression of ATAD2 mRNA
CTD
PMID:20713471
NCBI chr 8:123,319,850...123,416,350
Ensembl chr 8:123,319,850...123,416,350
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ATOX1
antioxidant 1 copper chaperone
increases expression
ISO
Methylcholanthrene results in increased expression of ATOX1 mRNA
CTD
PMID:23273579
NCBI chr 5:151,742,822...151,758,631
Ensembl chr 5:151,742,316...151,772,532
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ATP6V1C2
ATPase H+ transporting V1 subunit C2
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ATP6V1C2 mRNA
CTD
PMID:23519560
NCBI chr 2:10,720,943...10,785,110
Ensembl chr 2:10,721,100...10,785,110
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AURKA
aurora kinase A
increases expression
ISO
Methylcholanthrene results in increased expression of AURKA mRNA
CTD
PMID:20713471
NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337
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AURKB
aurora kinase B
increases expression
ISO
Methylcholanthrene results in increased expression of AURKB mRNA
CTD
PMID:20713471
NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600
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BAD
BCL2 associated agonist of cell death
increases expression
ISO
Methylcholanthrene results in increased expression of BAD mRNA
CTD
PMID:23273579
NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
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BAIAP2
BAR/IMD domain containing adaptor protein 2
increases expression
ISO
Methylcholanthrene results in increased expression of BAIAP2 mRNA
CTD
PMID:20713471
NCBI chr17:81,035,151...81,117,434
Ensembl chr17:81,035,122...81,117,434
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BAMBI
BMP and activin membrane bound inhibitor
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to BAMBI promoter]
CTD
PMID:20348232
NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932
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BAX
BCL2 associated X, apoptosis regulator
increases expression multiple interactions increases methylation
ISO
Methylcholanthrene results in increased expression of BAX mRNA alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of BAX mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of BAX promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]
CTD
PMID:23273579 PMID:29094188
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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BBX
BBX high mobility group box domain containing
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to BBX promoter]
CTD
PMID:20348232
NCBI chr 3:107,522,962...107,811,339
Ensembl chr 3:107,522,936...107,811,339
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BCAS3
BCAS3 microtubule associated cell migration factor
decreases expression
EXP
Methylcholanthrene results in decreased expression of BCAS3 mRNA
CTD
PMID:22100608
NCBI chr17:60,677,851...61,392,831
Ensembl chr17:60,677,453...61,392,838
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BCL10
BCL10 immune signaling adaptor
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of BCL10 mRNA
CTD
PMID:25926378
NCBI chr 1:85,265,776...85,276,632
Ensembl chr 1:85,265,776...85,276,632
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BCL2
BCL2 apoptosis regulator
increases expression decreases expression
ISO
Methylcholanthrene results in increased expression of BCL2 mRNA Methylcholanthrene results in decreased expression of BCL2 mRNA
CTD
PMID:23273579 PMID:35487396
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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BCL6
BCL6 transcription repressor
increases expression multiple interactions
ISO EXP
Methylcholanthrene results in increased expression of BCL6 mRNA Methylcholanthrene promotes the reaction [AHR protein binds to BCL6 promoter]
CTD
PMID:20348232 PMID:20713471 PMID:25926378
NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725
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BDH2
3-hydroxybutyrate dehydrogenase 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of BDH2 mRNA
CTD
PMID:20713471
NCBI chr 4:103,077,592...103,099,834
Ensembl chr 4:103,077,592...103,099,870
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BIRC3
baculoviral IAP repeat containing 3
increases expression
ISO
Methylcholanthrene results in increased expression of BIRC3 mRNA
CTD
PMID:29554273
NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
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BIRC5
baculoviral IAP repeat containing 5
increases expression
ISO
Methylcholanthrene results in increased expression of BIRC5 mRNA
CTD
PMID:20713471
NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
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BMF
Bcl2 modifying factor
increases expression
ISO
Methylcholanthrene results in increased expression of BMF mRNA
CTD
PMID:29554273
NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892
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BMP15
bone morphogenetic protein 15
multiple interactions
ISO
[Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of BMP15 mRNA
CTD
PMID:29094188
NCBI chr X:50,910,735...50,916,641
Ensembl chr X:50,910,735...50,916,641
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BMP4
bone morphogenetic protein 4
decreases expression
ISO
Methylcholanthrene results in decreased expression of BMP4 mRNA
CTD
PMID:29094188
NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
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BPGM
bisphosphoglycerate mutase
increases expression
ISO
Methylcholanthrene results in increased expression of BPGM mRNA
CTD
PMID:20713471
NCBI chr 7:134,646,853...134,679,816
Ensembl chr 7:134,646,811...134,679,816
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BPIFA2
BPI fold containing family A member 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to BPIFA2 promoter]
CTD
PMID:20348232
NCBI chr20:33,161,770...33,181,412
Ensembl chr20:33,161,768...33,181,412
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BRCA1
BRCA1 DNA repair associated
multiple interactions increases expression
EXP ISO
Methylcholanthrene promotes the reaction [AHR protein binds to BRCA1 protein] Methylcholanthrene results in increased expression of BRCA1 mRNA
CTD
PMID:18259752 PMID:20713471
NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245
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BRI3BP
BRI3 binding protein
increases expression
ISO
Methylcholanthrene results in increased expression of BRI3BP mRNA
CTD
PMID:25926378
NCBI chr12:124,993,645...125,051,167
Ensembl chr12:124,993,645...125,031,231
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BRIP1
BRCA1 interacting helicase 1
increases expression
ISO
Methylcholanthrene results in increased expression of BRIP1 mRNA
CTD
PMID:20713471
NCBI chr17:61,679,139...61,863,528
Ensembl chr17:61,679,139...61,863,559
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BRWD1-AS2
BRWD1 antisense RNA 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to BRWD1-AS2 promoter]
CTD
PMID:20348232
NCBI chr21:39,313,907...39,314,915
Ensembl chr21:39,313,907...39,314,962
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BST1
bone marrow stromal cell antigen 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BST1 mRNA
CTD
PMID:23519560
NCBI chr 4:15,703,065...15,774,173
Ensembl chr 4:15,703,065...15,738,313
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BTG2
BTG anti-proliferation factor 2
increases expression
EXP
Methylcholanthrene results in increased expression of BTG2 mRNA
CTD
PMID:22100608
NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
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BUB1
BUB1 mitotic checkpoint serine/threonine kinase
increases expression
ISO
Methylcholanthrene results in increased expression of BUB1 mRNA
CTD
PMID:20713471
NCBI chr 2:110,637,528...110,678,063
Ensembl chr 2:110,637,528...110,678,063
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BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
increases expression
ISO
Methylcholanthrene results in increased expression of BUB1B mRNA
CTD
PMID:20713471
NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123
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C16orf74
chromosome 16 open reading frame 74
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to C16ORF74 promoter]
CTD
PMID:20348232
NCBI chr16:85,707,517...85,751,096
Ensembl chr16:85,690,084...85,751,129
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C1QBP
complement C1q binding protein
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of C1QBP mRNA
CTD
PMID:25926378
NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830
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C3
complement C3
increases expression
EXP ISO
Methylcholanthrene results in increased expression of C3 mRNA
CTD
PMID:16257430 PMID:29554273
NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
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C4A
complement C4A (Chido/Rodgers blood group)
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4A mRNA
CTD
PMID:23519560
NCBI chr 6:31,982,057...32,002,681
Ensembl chr 6:31,982,057...32,002,681
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C4B
complement C4B (Chido/Rodgers blood group)
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4B mRNA
CTD
PMID:23519560
NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
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C4orf19
chromosome 4 open reading frame 19
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF19 promoter]
CTD
PMID:20348232
NCBI chr 4:37,453,255...37,593,510
Ensembl chr 4:37,453,925...37,623,495
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C4orf36
chromosome 4 open reading frame 36
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF36 promoter]
CTD
PMID:20348232
NCBI chr 4:86,876,205...86,936,204
Ensembl chr 4:86,876,205...86,892,422 Ensembl chr 4:86,876,205...86,892,422
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C6
complement C6
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of C6 mRNA
CTD
PMID:25926378
NCBI chr 5:41,142,116...41,261,469
Ensembl chr 5:41,142,116...41,261,438
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CA12
carbonic anhydrase 12
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CA12 promoter]
CTD
PMID:20348232
NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846
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CA8
carbonic anhydrase 8
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CA8 promoter]
CTD
PMID:20348232
NCBI chr 8:60,185,412...60,281,400
Ensembl chr 8:60,185,412...60,281,400
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CACNA1B
calcium voltage-gated channel subunit alpha1 B
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CACNA1B promoter]
CTD
PMID:20348232
NCBI chr 9:137,877,782...138,124,619
Ensembl chr 9:137,877,782...138,124,624
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CACNA1G
calcium voltage-gated channel subunit alpha1 G
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CACNA1G mRNA
CTD
PMID:23519560
NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
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CADM1
cell adhesion molecule 1
multiple interactions
ISO
[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of CADM1 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of CADM1 gene
CTD
PMID:21163286
NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957
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CALB2
calbindin 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CALB2 promoter]
CTD
PMID:20348232
NCBI chr16:71,358,723...71,390,433
Ensembl chr16:71,358,713...71,390,436
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CALCRL
calcitonin receptor like receptor
decreases expression
ISO
Methylcholanthrene results in decreased expression of CALCRL mRNA
CTD
PMID:20713471
NCBI chr 2:187,341,964...187,448,252
Ensembl chr 2:187,341,964...187,448,460
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CALM1
calmodulin 1
increases expression
ISO
Methylcholanthrene results in increased expression of CALM1 mRNA
CTD
PMID:20713471
NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
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CALR
calreticulin
multiple interactions increases expression
ISO
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CALR mRNA]
CTD
PMID:29094188
NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
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CAMK2B
calcium/calmodulin dependent protein kinase II beta
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAMK2B mRNA
CTD
PMID:23519560
NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577
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CAPG
capping actin protein, gelsolin like
increases expression
ISO
Methylcholanthrene results in increased expression of CAPG mRNA
CTD
PMID:20713471
NCBI chr 2:85,391,602...85,419,540
Ensembl chr 2:85,394,753...85,418,432
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CAPS
calcyphosine
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of TNFRSF23 mRNA [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of TNFRSF23 mRNA
CTD
PMID:20713471 PMID:25926378
NCBI chr19:5,914,254...5,916,211
Ensembl chr19:5,912,339...5,916,211
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CASK
calcium/calmodulin dependent serine protein kinase
decreases expression
ISO
Methylcholanthrene results in decreased expression of CASK mRNA
CTD
PMID:20713471
NCBI chr X:41,514,934...41,923,554
Ensembl chr X:41,514,934...41,923,554
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CASP3
caspase 3
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of CASP3 mRNA Methylcholanthrene inhibits the reaction [3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole results in increased cleavage of and results in increased activity of CASP3 protein]
CTD
PMID:11323195 PMID:11999409 PMID:20713471
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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CASP9
caspase 9
increases expression increases methylation multiple interactions
ISO
Methylcholanthrene results in increased expression of CASP9 mRNA Methylcholanthrene results in increased methylation of CASP9 promoter [alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of CASP9 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CASP9 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CASP9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]
CTD
PMID:23273579 PMID:29094188
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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CAST
calpastatin
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CAST promoter]
CTD
PMID:20348232
NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,525,267...96,779,595 Ensembl chr 5:96,525,267...96,779,595
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CCDC144NL
CCDC144A N-terminal like (pseudogene)
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CCDC144NL promoter]
CTD
PMID:20348232
NCBI chr17:20,863,395...20,896,163
Ensembl chr17:20,836,447...20,896,162 Ensembl chr17:20,836,447...20,896,162
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CCDC57
coiled-coil domain containing 57
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CCDC57 promoter]
CTD
PMID:20348232
NCBI chr17:82,101,470...82,212,842
Ensembl chr17:82,101,460...82,212,878
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CCDC6
coiled-coil domain containing 6
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CCDC6 promoter]
CTD
PMID:20348232
NCBI chr10:59,788,747...59,906,556
Ensembl chr10:59,788,747...59,906,556
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CCL17
C-C motif chemokine ligand 17
decreases expression
ISO
Methylcholanthrene results in decreased expression of CCL17 mRNA
CTD
PMID:29554273
NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063
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CCL19
C-C motif chemokine ligand 19
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CCL19 mRNA
CTD
PMID:25926378
NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276
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CCL2
C-C motif chemokine ligand 2
increases expression
EXP ISO
Methylcholanthrene results in increased expression of CCL2 mRNA
CTD
PMID:20713471 PMID:23397585
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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CCL23
C-C motif chemokine ligand 23
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CCL9 mRNA
CTD
PMID:23519560
NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972
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CCL5
C-C motif chemokine ligand 5
decreases expression
ISO
Methylcholanthrene results in decreased expression of CCL5 mRNA
CTD
PMID:20713471
NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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CCL7
C-C motif chemokine ligand 7
increases expression
ISO
Methylcholanthrene results in increased expression of CCL7 mRNA
CTD
PMID:20713471
NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
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CCL8
C-C motif chemokine ligand 8
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of CCL8 mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CCL8 mRNA
CTD
PMID:20713471 PMID:23519560
NCBI chr17:34,319,435...34,321,402
Ensembl chr17:34,319,435...34,321,402
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CCN1
cellular communication network factor 1
increases expression
ISO
Methylcholanthrene results in increased expression of CCN1 mRNA
CTD
PMID:20713471
NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
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CCN3
cellular communication network factor 3
increases expression
ISO
Methylcholanthrene results in increased expression of CCN3 mRNA
CTD
PMID:20713471
NCBI chr 8:119,416,446...119,424,434
Ensembl chr 8:119,416,446...119,424,434
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CCN4
cellular communication network factor 4
decreases expression
ISO
Methylcholanthrene results in decreased expression of CCN4 mRNA
CTD
PMID:20713471
NCBI chr 8:133,191,039...133,231,690
Ensembl chr 8:133,191,039...133,231,690
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CCN5
cellular communication network factor 5
increases expression multiple interactions
ISO EXP
Methylcholanthrene results in increased expression of CCN5 mRNA Methylcholanthrene promotes the reaction [AHR protein binds to CCN5 promoter]
CTD
PMID:20348232 PMID:20713471
NCBI chr20:44,714,861...44,727,811
Ensembl chr20:44,714,844...44,728,509
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CCNA2
cyclin A2
increases expression
ISO
Methylcholanthrene results in increased expression of CCNA2 mRNA
CTD
PMID:20713471
NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
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CCNB1
cyclin B1
increases expression
ISO
Methylcholanthrene results in increased expression of CCNB1 mRNA
CTD
PMID:20713471 PMID:26372666
NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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CCNB2
cyclin B2
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of CCNB2 mRNA Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of CCNB2 mRNA]
CTD
PMID:20713471 PMID:26372666
NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
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CCND1
cyclin D1
increases expression
ISO
Methylcholanthrene results in increased expression of CCND1 mRNA
CTD
PMID:20713471
NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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CCNE1
cyclin E1
increases expression
ISO
Methylcholanthrene results in increased expression of CCNE1 mRNA
CTD
PMID:29554273
NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
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CCNE2
cyclin E2
increases expression
ISO
Methylcholanthrene results in increased expression of CCNE2 mRNA
CTD
PMID:20713471
NCBI chr 8:94,880,224...94,896,693
Ensembl chr 8:94,879,770...94,896,678
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CCNG2
cyclin G2
multiple interactions increases expression
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of CCNG2 mRNA]
CTD
PMID:20348232
NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388
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CD300E
CD300e molecule
increases expression
ISO
Methylcholanthrene results in increased expression of CD300E mRNA
CTD
PMID:25926378
NCBI chr17:74,609,885...74,623,738
Ensembl chr17:74,609,885...74,623,738
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CD300LB
CD300 molecule like family member b
increases expression
ISO
Methylcholanthrene results in increased expression of CD300LB mRNA
CTD
PMID:20713471
NCBI chr17:74,521,174...74,531,475
Ensembl chr17:74,521,174...74,531,475
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CD3D
CD3 delta subunit of T-cell receptor complex
decreases expression
ISO
Methylcholanthrene results in decreased expression of CD3D mRNA
CTD
PMID:25926378
NCBI chr11:118,338,954...118,342,705
Ensembl chr11:118,339,075...118,342,705
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CD44
CD44 molecule (IN blood group)
multiple interactions increases expression
ISO
[Butylated Hydroxytoluene co-treated with Methylcholanthrene] results in increased expression of CD44 mRNA alternative form Methylcholanthrene results in increased expression of CD44 mRNA
CTD
PMID:15390079 PMID:20713471
NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
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CD48
CD48 molecule
increases expression
ISO
Methylcholanthrene results in increased expression of CD48 mRNA
CTD
PMID:20713471
NCBI chr 1:160,678,746...160,711,822
Ensembl chr 1:160,678,746...160,711,831
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CD5
CD5 molecule
increases expression
ISO
Methylcholanthrene results in increased expression of CD5 mRNA
CTD
PMID:25926378
NCBI chr11:61,093,963...61,127,852
Ensembl chr11:61,102,489...61,127,852
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CD55
CD55 molecule (Cromer blood group)
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CD55 promoter]
CTD
PMID:20348232
NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
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CD59
CD59 molecule (CD59 blood group)
increases mutagenesis
EXP
Methylcholanthrene results in increased mutagenesis of CD59 protein
CTD
PMID:17045307
NCBI chr11:33,703,010...33,736,479
Ensembl chr11:33,703,010...33,736,479
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CD9
CD9 molecule
decreases expression multiple interactions
ISO
Methylcholanthrene results in decreased expression of CD9 mRNA alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of CD9 mRNA]
CTD
PMID:29094188
NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271
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CD96
CD96 molecule
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CD96 mRNA
CTD
PMID:25926378
NCBI chr 3:111,542,197...111,665,996
Ensembl chr 3:111,292,719...111,665,750
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CDA
cytidine deaminase
increases expression
ISO
Methylcholanthrene results in increased expression of CDA mRNA
CTD
PMID:20713471
NCBI chr 1:20,589,097...20,618,903
Ensembl chr 1:20,589,086...20,618,903
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CDC20
cell division cycle 20
increases expression
ISO
Methylcholanthrene results in increased expression of CDC20 mRNA
CTD
PMID:20713471
NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203
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CDC25C
cell division cycle 25C
increases expression
ISO
Methylcholanthrene results in increased expression of CDC25C mRNA
CTD
PMID:20713471
NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355
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CDC45
cell division cycle 45
increases expression
ISO
Methylcholanthrene results in increased expression of CDC45 mRNA
CTD
PMID:20713471
NCBI chr22:19,479,466...19,520,612
Ensembl chr22:19,479,457...19,520,612
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CDC6
cell division cycle 6
increases expression
ISO
Methylcholanthrene results in increased expression of CDC6 mRNA
CTD
PMID:20713471
NCBI chr17:40,287,879...40,304,657
Ensembl chr17:40,287,879...40,304,657
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CDCA2
cell division cycle associated 2
increases expression
ISO
Methylcholanthrene results in increased expression of CDCA2 mRNA
CTD
PMID:20713471
NCBI chr 8:25,458,931...25,507,917
Ensembl chr 8:25,459,199...25,507,911
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CDCA3
cell division cycle associated 3
increases expression
ISO
Methylcholanthrene results in increased expression of CDCA3 mRNA
CTD
PMID:20713471
NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292
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CDCA5
cell division cycle associated 5
increases expression
ISO
Methylcholanthrene results in increased expression of CDCA5 mRNA
CTD
PMID:20713471
NCBI chr11:65,061,093...65,084,040
Ensembl chr11:65,066,300...65,084,164
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CDCA8
cell division cycle associated 8
increases expression
ISO
Methylcholanthrene results in increased expression of CDCA8 mRNA
CTD
PMID:20713471
NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719
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CDH1
cadherin 1
decreases expression
EXP
Methylcholanthrene results in decreased expression of CDH1 protein
CTD
PMID:16619036
NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
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CDH13
cadherin 13
decreases expression
ISO
Methylcholanthrene results in decreased expression of CDH13 mRNA
CTD
PMID:20713471
NCBI chr16:82,626,969...83,800,640
Ensembl chr16:82,626,965...83,800,640
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CDH2
cadherin 2
multiple interactions
ISO
[Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of CDH2 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased expression of CDH2 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of CDH2 gene
CTD
PMID:21163286
NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946
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CDH5
cadherin 5
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CDH5 mRNA
CTD
PMID:25926378
NCBI chr16:66,366,691...66,404,784
Ensembl chr16:66,366,690...66,404,784
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CDK2
cyclin dependent kinase 2
decreases expression multiple interactions decreases methylation increases expression increases acetylation
EXP ISO
Methylcholanthrene results in decreased expression of CDK2 protein alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased methylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CDK2 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]
CTD
PMID:18022818 PMID:29094188
NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
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CDKN1A
cyclin dependent kinase inhibitor 1A
increases expression increases response to substance multiple interactions
ISO EXP
Methylcholanthrene results in increased expression of CDKN1A mRNA Methylcholanthrene results in increased expression of CDKN1A protein CDKN1A protein results in increased susceptibility to Methylcholanthrene Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein]; resveratrol inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein] SB 203580 inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A mRNA]
CTD
PMID:15882963 PMID:18022818
NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
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CDKN1B
cyclin dependent kinase inhibitor 1B
multiple interactions increases response to substance increases expression
EXP
Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1B protein]; resveratrol inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1B protein] CDKN1B protein results in increased susceptibility to Methylcholanthrene
CTD
PMID:18022818
NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
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CDKN2AIPNL
CDKN2A interacting protein N-terminal like
increases expression
ISO
Methylcholanthrene results in increased expression of CDKN2AIPNL mRNA
CTD
PMID:20713471
NCBI chr 5:134,402,065...134,411,881
Ensembl chr 5:134,402,065...134,411,881
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CDKN3
cyclin dependent kinase inhibitor 3
increases expression
ISO
Methylcholanthrene results in increased expression of CDKN3 mRNA
CTD
PMID:20713471
NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218
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CDT1
chromatin licensing and DNA replication factor 1
increases expression
ISO
Methylcholanthrene results in increased expression of CDT1 mRNA
CTD
PMID:20713471
NCBI chr16:88,803,789...88,809,258
Ensembl chr16:88,803,789...88,809,258
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CEACAM19
CEA cell adhesion molecule 19
increases expression
ISO
Methylcholanthrene results in increased expression of CEACAM19 mRNA
CTD
PMID:25926378
NCBI chr19:44,665,860...44,684,355
Ensembl chr19:44,662,278...44,684,359
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CEACAM3
CEA cell adhesion molecule 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CEACAM3 promoter]
CTD
PMID:20348232
NCBI chr19:41,796,587...41,811,554
Ensembl chr19:41,796,587...41,811,554
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CEBPA
CCAAT enhancer binding protein alpha
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CEBPA mRNA
CTD
PMID:23519560
NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
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CEBPB
CCAAT enhancer binding protein beta
multiple interactions
ISO
[Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]
CTD
PMID:21250977
NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
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CENPA
centromere protein A
increases expression
ISO
Methylcholanthrene results in increased expression of CENPA mRNA
CTD
PMID:20713471
NCBI chr 2:26,786,056...26,794,589
Ensembl chr 2:26,764,289...26,801,067
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CENPE
centromere protein E
increases expression
ISO
Methylcholanthrene results in increased expression of CENPE mRNA
CTD
PMID:20713471
NCBI chr 4:103,105,811...103,198,343
Ensembl chr 4:103,105,349...103,198,445
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CENPF
centromere protein F
increases expression
ISO
Methylcholanthrene results in increased expression of CENPF mRNA
CTD
PMID:20713471
NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574
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CENPH
centromere protein H
increases expression
ISO
Methylcholanthrene results in increased expression of CENPH mRNA
CTD
PMID:20713471
NCBI chr 5:69,189,583...69,210,357
Ensembl chr 5:69,189,574...69,210,357
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CENPI
centromere protein I
increases expression
ISO
Methylcholanthrene results in increased expression of CENPI mRNA
CTD
PMID:20713471
NCBI chr X:101,098,204...101,181,859
Ensembl chr X:101,098,188...101,166,126
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CENPK
centromere protein K
increases expression
ISO
Methylcholanthrene results in increased expression of CENPK mRNA
CTD
PMID:20713471
NCBI chr 5:65,495,624...65,563,168
Ensembl chr 5:65,517,766...65,563,168
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CENPL
centromere protein L
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CENPL promoter]
CTD
PMID:20348232
NCBI chr 1:173,799,550...173,824,883
Ensembl chr 1:173,799,550...173,824,883
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CENPU
centromere protein U
increases expression
ISO
Methylcholanthrene results in increased expression of CENPU mRNA
CTD
PMID:20713471
NCBI chr 4:184,694,085...184,734,096
Ensembl chr 4:184,694,085...184,734,130
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CEP55
centrosomal protein 55
increases expression
ISO
Methylcholanthrene results in increased expression of CEP55 mRNA
CTD
PMID:20713471
NCBI chr10:93,496,612...93,529,092
Ensembl chr10:93,496,612...93,529,092
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CEP70
centrosomal protein 70
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CEP70 promoter]
CTD
PMID:20348232
NCBI chr 3:138,494,344...138,594,260
Ensembl chr 3:138,494,344...138,594,538
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CES1
carboxylesterase 1
decreases expression
EXP
Methylcholanthrene results in decreased expression of CES1 protein
CTD
PMID:10640517
NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337
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CES2
carboxylesterase 2
decreases expression
EXP
Methylcholanthrene results in decreased expression of CES2 protein
CTD
PMID:10640517
NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096
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CES3
carboxylesterase 3
increases expression
ISO
Methylcholanthrene results in increased expression of CES3 mRNA
CTD
PMID:20713471
NCBI chr16:66,961,266...66,975,149
Ensembl chr16:66,961,245...66,975,149
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CFAP61
cilia and flagella associated protein 61
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CFAP61 promoter]
CTD
PMID:20348232
NCBI chr20:20,052,532...20,360,698
Ensembl chr20:20,052,514...20,360,703
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CHD1L
chromodomain helicase DNA binding protein 1 like
increases expression
ISO
Methylcholanthrene results in increased expression of CHD1L mRNA
CTD
PMID:25926378
NCBI chr 1:147,172,747...147,295,762
Ensembl chr 1:147,242,654...147,295,765
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CHD8
chromodomain helicase DNA binding protein 8
increases expression
ISO
Methylcholanthrene results in increased expression of CHD8 mRNA
CTD
PMID:25926378
NCBI chr14:21,385,199...21,456,123
Ensembl chr14:21,385,194...21,456,126
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CHFR
checkpoint with forkhead and ring finger domains
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CHFR mRNA
CTD
PMID:25926378
NCBI chr12:132,832,356...132,887,618
Ensembl chr12:132,822,187...132,956,304
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CHI3L1
chitinase 3 like 1
increases expression
ISO
Methylcholanthrene results in increased expression of CHI3L1 mRNA
CTD
PMID:20713471
NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
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CHIC1
cysteine rich hydrophobic domain 1
increases expression
ISO
Methylcholanthrene results in increased expression of CHIC1 mRNA
CTD
PMID:20713471
NCBI chr X:73,563,148...73,687,111
Ensembl chr X:73,563,197...73,687,111
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CHIC2
cysteine rich hydrophobic domain 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CHIC2 mRNA
CTD
PMID:25926378
NCBI chr 4:54,009,789...54,091,879
Ensembl chr 4:54,009,789...54,064,605
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CHKA
choline kinase alpha
increases expression
ISO
Methylcholanthrene results in increased expression of CHKA mRNA
CTD
PMID:7852267
NCBI chr11:68,052,859...68,121,388
Ensembl chr11:68,052,859...68,121,444
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CHPT1
choline phosphotransferase 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CHPT1 promoter]
CTD
PMID:20348232
NCBI chr12:101,697,640...101,729,074
Ensembl chr12:101,696,947...101,744,140
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CHRDL2
chordin like 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CHRDL2 promoter]
CTD
PMID:20348232
NCBI chr11:74,696,429...74,731,426
Ensembl chr11:74,696,429...74,731,426
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CHRNB1
cholinergic receptor nicotinic beta 1 subunit
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CHRNB1 mRNA
CTD
PMID:23519560
NCBI chr17:7,445,061...7,457,710
Ensembl chr17:7,445,061...7,457,710
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CILK1
ciliogenesis associated kinase 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CILK1 promoter]
CTD
PMID:20348232
NCBI chr 6:53,001,303...53,061,824
Ensembl chr 6:53,001,279...53,061,824
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CISD1
CDGSH iron sulfur domain 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CISD1 promoter]
CTD
PMID:20348232
NCBI chr10:58,269,162...58,289,586
Ensembl chr10:58,269,162...58,289,586
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CISH
cytokine inducible SH2 containing protein
decreases expression
ISO
Methylcholanthrene results in decreased expression of CISH mRNA
CTD
PMID:22978700
NCBI chr 3:50,606,489...50,611,774
Ensembl chr 3:50,606,489...50,611,774
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CKAP2
cytoskeleton associated protein 2
increases expression
ISO
Methylcholanthrene results in increased expression of CKAP2 mRNA
CTD
PMID:20713471
NCBI chr13:52,455,478...52,476,627
Ensembl chr13:52,455,429...52,476,628
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CKAP2L
cytoskeleton associated protein 2 like
increases expression
ISO
Methylcholanthrene results in increased expression of CKAP2L mRNA
CTD
PMID:20713471
NCBI chr 2:112,736,349...112,764,609
Ensembl chr 2:112,736,349...112,764,664
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CKS2
CDC28 protein kinase regulatory subunit 2
increases expression
ISO
Methylcholanthrene results in increased expression of CKS2 mRNA
CTD
PMID:20713471
NCBI chr 9:89,311,195...89,316,703
Ensembl chr 9:89,311,195...89,316,703
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CLDN17
claudin 17
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CLDN17 promoter]
CTD
PMID:20348232
NCBI chr21:30,165,565...30,166,805
Ensembl chr21:30,165,565...30,166,805
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CLK3
CDC like kinase 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CLK3 promoter]
CTD
PMID:20348232
NCBI chr15:74,608,372...74,630,201
Ensembl chr15:74,598,500...74,645,414
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CLPSL2
colipase like 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CLPSL2 promoter]
CTD
PMID:20348232
NCBI chr 6:35,776,598...35,779,552
Ensembl chr 6:35,776,594...35,779,552
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CLSPN
claspin
increases expression
ISO
Methylcholanthrene results in increased expression of CLSPN mRNA
CTD
PMID:20713471
NCBI chr 1:35,720,213...35,769,978
Ensembl chr 1:35,720,218...35,769,978
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CMIP
c-Maf inducing protein
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CMIP mRNA
CTD
PMID:25926378
NCBI chr16:81,444,808...81,711,762
Ensembl chr16:81,444,808...81,711,762
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CNST
consortin, connexin sorting protein
increases expression
EXP
Methylcholanthrene results in increased expression of CNST mRNA
CTD
PMID:23397585
NCBI chr 1:246,566,456...246,668,595
Ensembl chr 1:246,566,444...246,668,595
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CNTN1
contactin 1
increases expression
ISO
Methylcholanthrene results in increased expression of CNTN1 mRNA
CTD
PMID:20713471
NCBI chr12:40,692,439...41,072,415
Ensembl chr12:40,692,439...41,072,415
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COL11A1
collagen type XI alpha 1 chain
decreases expression
ISO
Methylcholanthrene results in decreased expression of COL11A1 mRNA
CTD
PMID:20713471
NCBI chr 1:102,876,473...103,108,522
Ensembl chr 1:102,876,467...103,108,872
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COL3A1
collagen type III alpha 1 chain
decreases expression
ISO
Methylcholanthrene results in decreased expression of COL3A1 mRNA
CTD
PMID:20713471
NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
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COL5A1
collagen type V alpha 1 chain
decreases expression
ISO
Methylcholanthrene results in decreased expression of COL5A1 mRNA
CTD
PMID:20713471
NCBI chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843
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COL5A2
collagen type V alpha 2 chain
decreases expression
ISO
Methylcholanthrene results in decreased expression of COL5A2 mRNA
CTD
PMID:20713471
NCBI chr 2:189,031,898...189,441,111
Ensembl chr 2:189,031,898...189,225,312
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COL8A1
collagen type VIII alpha 1 chain
decreases expression
ISO
Methylcholanthrene results in decreased expression of COL8A1 mRNA
CTD
PMID:20713471
NCBI chr 3:99,638,594...99,799,217
Ensembl chr 3:99,638,475...99,799,226
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COLCA1
colorectal cancer associated 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to COLCA1 promoter]
CTD
PMID:20348232
NCBI chr11:111,293,389...111,305,048
Ensembl chr11:111,290,787...111,305,498
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COTL1
coactosin like F-actin binding protein 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of COTL1 mRNA
CTD
PMID:20713471
NCBI chr16:84,565,596...84,618,078
Ensembl chr16:84,565,596...84,618,078
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COX4I1
cytochrome c oxidase subunit 4I1
multiple interactions increases expression
EXP ISO
Methylcholanthrene promotes the reaction [AHR protein binds to COX4I1 promoter] Methylcholanthrene results in increased expression of COX4I1 mRNA
CTD
PMID:20348232 PMID:23273579
NCBI chr16:85,799,695...85,807,068
Ensembl chr16:85,798,633...85,807,068
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CPOX
coproporphyrinogen oxidase
increases expression
ISO
Methylcholanthrene results in increased expression of CPOX mRNA
CTD
PMID:20713471
NCBI chr 3:98,570,488...98,593,611
Ensembl chr 3:98,579,446...98,593,648
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CPT1A
carnitine palmitoyltransferase 1A
increases expression
ISO
Methylcholanthrene results in increased expression of CPT1A protein
CTD
PMID:25786523
NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
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CREB1
cAMP responsive element binding protein 1
increases expression
ISO
Methylcholanthrene results in increased expression of CREB1 mRNA
CTD
PMID:23273579
NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
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CREM
cAMP responsive element modulator
decreases expression
ISO
Methylcholanthrene results in decreased expression of CREM mRNA
CTD
PMID:35487396
NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
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CRKL
CRK like proto-oncogene, adaptor protein
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CRKL promoter]
CTD
PMID:20348232
NCBI chr22:20,917,407...20,953,747
Ensembl chr22:20,917,407...20,953,747
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CRYZ
crystallin zeta
multiple interactions increases activity increases expression
ISO
AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Copper inhibits the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Copper inhibits the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA]; Lead inhibits the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA]; Lead promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Mercury promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA] sanguinarine inhibits the reaction [Methylcholanthrene results in increased activity of CRYZ protein]
CTD
PMID:15297030 PMID:19788401
NCBI chr 1:74,705,486...74,733,050
Ensembl chr 1:74,705,482...74,733,408
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CSMD3
CUB and Sushi multiple domains 3
decreases expression
ISO
Methylcholanthrene results in decreased expression of CSMD3 mRNA
CTD
PMID:20713471
NCBI chr 8:112,222,928...113,436,939
Ensembl chr 8:112,222,928...113,436,939
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CSN2
casein beta
multiple interactions
ISO
Methylcholanthrene inhibits the reaction [8-prenylnaringenin results in increased expression of CSN2 mRNA]
CTD
PMID:26372666
NCBI chr 4:69,955,256...69,965,728
Ensembl chr 4:69,955,256...69,965,728
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CSRP2
cysteine and glycine rich protein 2
increases expression
ISO
Methylcholanthrene results in increased expression of CSRP2 mRNA
CTD
PMID:20713471
NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023
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CTNNA1
catenin alpha 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CTNNA1 promoter]
CTD
PMID:20348232
NCBI chr 5:138,753,425...138,935,034
Ensembl chr 5:138,610,967...138,935,034
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CTNNB1
catenin beta 1
affects response to substance increases response to substance multiple interactions
ISO
CTNNB1 protein affects the susceptibility to Methylcholanthrene CTNNB1 protein results in increased susceptibility to Methylcholanthrene CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CTNNB1 protein affects the reaction [[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]
CTD
PMID:21498875 PMID:25174530
NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
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CTSD
cathepsin D
increases expression
EXP
Methylcholanthrene results in increased expression of CTSD mRNA
CTD
PMID:16257430
NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
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CUEDC1
CUE domain containing 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CUEDC1 promoter]
CTD
PMID:20348232
NCBI chr17:57,861,243...57,955,412
Ensembl chr17:57,861,243...57,955,412
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CX3CL1
C-X3-C motif chemokine ligand 1
increases expression
ISO
Methylcholanthrene results in increased expression of CX3CL1 mRNA
CTD
PMID:20713471
NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
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CXCL10
C-X-C motif chemokine ligand 10
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL10 mRNA
CTD
PMID:23519560
NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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CXCL12
C-X-C motif chemokine ligand 12
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL12 mRNA
CTD
PMID:23519560
NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
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CXCL8
C-X-C motif chemokine ligand 8
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL5 mRNA
CTD
PMID:23519560
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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CYB5B
cytochrome b5 type B
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CYB5B promoter]
CTD
PMID:20348232
NCBI chr16:69,424,619...69,466,264
Ensembl chr16:69,398,402...69,466,264
G
CYP11A1
cytochrome P450 family 11 subfamily A member 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of CYP11A1 mRNA
CTD
PMID:35487396
NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
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CYP17A1
cytochrome P450 family 17 subfamily A member 1
affects expression
ISO
Methylcholanthrene affects the expression of CYP17A1 mRNA
CTD
PMID:35487396
NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
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CYP1A1
cytochrome P450 family 1 subfamily A member 1
multiple interactions increases expression decreases response to substance increases methylation increases acetylation increases activity increases metabolic processing decreases activity
EXP ISO
[Celsior co-treated with Methylcholanthrene] results in increased expression of CYP1A1 mRNA; [Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; [Methylcholanthrene co-treated with Oxygen deficiency] results in increased expression of CYP1A1 mRNA; [Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP1A1 mRNA; [Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [NR3C1 protein co-treated with Dexamethasone] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [pirinixic acid co-treated with Methylcholanthrene] results in increased activity of CYP1A1 protein; [pirinixic acid co-treated with Methylcholanthrene] results in increased expression of CYP1A1 mRNA; AHR gene mutant form inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; Arsenic Trioxide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Glyburide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [Nicardipine results in increased activity of and results in increased expression of CYP1A1 protein]; Methylcholanthrene promotes the reaction [Nicardipine results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [pirinixic acid results in increased activity of CYP1A1 protein]; Methylcholanthrene promotes the reaction [pirinixic acid results in increased expression of CYP1A1 mRNA]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein; Nicardipine promotes the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Oxygen deficiency affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; SPTLC1 protein inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; SPTLC1 protein mutant form inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; tyrphostin AG 1024 inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; tyrphostin AG 1024 inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein] 3-methylcholanthrene increases expression of mRNA, protein in rat heart CYP1A1 gene mutant form results in decreased susceptibility to Methylcholanthrene Methylcholanthrene results in increased methylation of CYP1A1 promoter Methylcholanthrene results in increased acetylation of CYP1A1 promoter Methylcholanthrene results in increased expression of CYP1A1 mRNA; Methylcholanthrene results in increased expression of CYP1A1 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; [Methylcholanthrene binds to and affects the localization of AHR protein] promotes the reaction [[AHR protein binds to CYP1A1 enhancer] which results in increased expression of CYP1A1 mRNA]; [Methylcholanthrene binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; AHR affects the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; AHR affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [Methylcholanthrene affects the expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Arsenic inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Arsenic promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Arsenic promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Cadmium inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Cadmium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Cadmium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Chromium inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Chromium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Chromium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Copper inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Copper inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Copper inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; CTNNB1 protein affects the reaction [[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; CYP1A1 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CYP1A2 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Lead inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Lead inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Mercury inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]; Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein; POR gene mutant form inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein] [[Methylcholanthrene results in increased expression of CYP1A1 protein] co-treated with [Methylcholanthrene results in increased expression of CYP1A2 protein]] results in decreased susceptibility to 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole; [Methylcholanthrene co-treated with GNMT protein] results in increased expression of CYP1A1 mRNA; AHR protein affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CYP1A1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CYP1A1 promoter]; Buthionine Sulfoximine inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Ethoxyquin inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; isoimperatorin promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Methylcholanthrene promotes the reaction [CYP1A1 protein results in increased oxidation of Toluene]; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A1 protein]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein; protocatechuic acid inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; sanguinarine inhibits the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; sodium arsenite inhibits the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; sodium arsenite inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA] CYP1A1 protein results in increased metabolism of Methylcholanthrene Methylcholanthrene results in increased activity of CYP1A1 promoter; Methylcholanthrene results in increased activity of CYP1A1 protein Methylcholanthrene results in decreased activity of CYP1A1 protein
CTD RGD
PMID:1316759 PMID:1617633 PMID:1994898 PMID:2154949 PMID:3785172 PMID:4054433 PMID:6749129 PMID:7238523 PMID:7493548 PMID:7756127 PMID:7980650 PMID:8163516 PMID:8902619 PMID:9152597 PMID:9233375 PMID:9261130 PMID:9783729 PMID:9860486 PMID:9973208 PMID:10329507 PMID:10476907 PMID:10772642 PMID:10799337 PMID:10859152 PMID:10872632 PMID:10874126 PMID:11158718 PMID:11285323 PMID:11328961 PMID:11356909 PMID:11502733 PMID:11768231 PMID:11999409 PMID:12107646 PMID:12117779 PMID:12458634 PMID:12490138 PMID:12490585 PMID:12505372 PMID:12700417 PMID:14672759 PMID:14987951 PMID:14993811 PMID:15297030 PMID:15302093 PMID:15337587 PMID:15350676 PMID:15448115 PMID:15521013 PMID:15582647 PMID:15585370 PMID:15590115 PMID:15620718 PMID:15621696 PMID:15860653 PMID:15885734 PMID:15946133 PMID:16137816 PMID:16167840 PMID:16257430 PMID:16359657 PMID:16489053 PMID:16619036 PMID:16639589 PMID:16829687 PMID:16906435 PMID:16968971 PMID:17069994 PMID:17230597 PMID:17253728 PMID:18486174 PMID:18493746 PMID:18502397 PMID:19022236 PMID:19043309 PMID:19118567 PMID:19525444 PMID:19788401 PMID:19853001 PMID:19883719 PMID:19889059 PMID:19951702 PMID:20020105 PMID:20067464 PMID:20171196 PMID:20226384 PMID:20348232 PMID:20350595 PMID:20570689 PMID:20570779 PMID:20713471 PMID:20816883 PMID:20881032 PMID:21250977 PMID:21292640 PMID:21498875 PMID:21666223 PMID:21800402 PMID:22507882 PMID:22761424 PMID:23169610 PMID:23273579 PMID:23712962 PMID:24091107 PMID:24486526 PMID:24999631 PMID:25174530 PMID:26006071 PMID:26651356 PMID:27055685 PMID:27163632 PMID:27590069 PMID:27644595 PMID:28601433 PMID:28887089 PMID:29094188 PMID:29554273 PMID:30503582 PMID:30842367 PMID:31776611 PMID:32726451 PMID:33811995 PMID:35149128 PMID:35487396 PMID:19889059 More...
RGD:401794453
NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
G
CYP1A2
cytochrome P450 family 1 subfamily A member 2
multiple interactions increases response to substance increases expression increases activity affects response to substance
EXP ISO
[Celsior co-treated with Methylcholanthrene] results in increased expression of CYP1A2 mRNA; [Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Dehydroepiandrosterone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Methylcholanthrene promotes the reaction [Nicardipine results in increased expression of CYP1A2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]]; Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Oxygen deficiency inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA] CYP1A2 gene mutant form results in increased susceptibility to Methylcholanthrene Methylcholanthrene results in increased expression of CYP1A2 mRNA; Methylcholanthrene results in increased expression of CYP1A2 protein [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CYP1A1 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CYP1A2 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA] [[Methylcholanthrene results in increased expression of CYP1A1 protein] co-treated with [Methylcholanthrene results in increased expression of CYP1A2 protein]] results in decreased susceptibility to 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole; [Methylcholanthrene results in increased activity of CYP1A2 protein] which results in increased oxidation of Uroporphyrinogens; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Methylcholanthrene promotes the reaction [CYP1A2 protein results in increased oxidation of Toluene]; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A2 protein]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A2 protein; protocatechuic acid inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]; sanguinarine inhibits the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A2 protein] CYP1A2 affects the susceptibility to Methylcholanthrene
CTD
PMID:1617633 PMID:1994898 PMID:3785172 PMID:4054433 PMID:6749129 PMID:7238523 PMID:7493548 PMID:8120057 PMID:8902619 PMID:9152597 PMID:9233375 PMID:9744552 PMID:9783729 PMID:10476907 PMID:10772642 PMID:11285323 PMID:11328961 PMID:11356909 PMID:11549291 PMID:11999409 PMID:12107646 PMID:12117779 PMID:15144902 PMID:15302093 PMID:15448115 PMID:15590115 PMID:15769886 PMID:15946133 PMID:16167840 PMID:16639589 PMID:18486174 PMID:18493746 PMID:19022236 PMID:19118567 PMID:19135037 PMID:19497360 PMID:19525444 PMID:19679878 PMID:19772856 PMID:19788401 PMID:19951702 PMID:20067464 PMID:20171196 PMID:20226384 PMID:20595379 PMID:20881032 PMID:21498875 PMID:23169610 PMID:23273579 PMID:23603339 PMID:25174530 PMID:27644595 PMID:27917125 PMID:28174063 PMID:28887089 PMID:30503582 PMID:30842367 PMID:31776611 PMID:32726451 PMID:33811995 More...
NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
G
CYP1B1
cytochrome P450 family 1 subfamily B member 1
multiple interactions increases expression increases metabolic processing increases chemical synthesis
EXP ISO
Methylcholanthrene promotes the reaction [AHR protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1B1 protein; Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA] 3-methylcholanthrene increases expression of mRNA, protein in rat heart Methylcholanthrene results in increased expression of CYP1B1 mRNA; Methylcholanthrene results in increased expression of CYP1B1 protein alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA] CYP1B1 protein results in increased metabolism of Methylcholanthrene CYP1B1 protein results in increased chemical synthesis of Methylcholanthrene metabolite
CTD RGD
PMID:9783729 PMID:10402558 PMID:11323195 PMID:11328961 PMID:11502733 PMID:11922910 PMID:12107646 PMID:12117779 PMID:15582647 PMID:15885734 PMID:17253728 PMID:19889059 PMID:19951702 PMID:20067464 PMID:20093341 PMID:20348232 PMID:20350595 PMID:20570779 PMID:20713471 PMID:20881032 PMID:23169610 PMID:23273579 PMID:23712962 PMID:27163632 PMID:28601433 PMID:28887089 PMID:29554273 PMID:35487396 PMID:19889059 More...
RGD:401794453
NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
G
CYP24A1
cytochrome P450 family 24 subfamily A member 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]
CTD
PMID:19244278
NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986
G
CYP2A13
cytochrome P450 family 2 subfamily A member 13
increases expression
ISO
Methylcholanthrene results in increased expression of CYP2A1 mRNA
CTD
PMID:11323195 PMID:19118567 PMID:22934830
NCBI chr19:41,088,451...41,096,195
Ensembl chr19:41,088,451...41,096,195
G
CYP2A6
cytochrome P450 family 2 subfamily A member 6
increases expression
ISO
Methylcholanthrene results in increased expression of CYP2A5 mRNA
CTD
PMID:30503582
NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
G
CYP2A7
cytochrome P450 family 2 subfamily A member 7
multiple interactions increases expression
EXP ISO
Methylcholanthrene promotes the reaction [AHR protein binds to CYP2A7 promoter] Methylcholanthrene results in increased expression of CYP2A4 mRNA Methylcholanthrene results in increased expression of CYP2A3 mRNA
CTD
PMID:12845369 PMID:20348232 PMID:22934830 PMID:30503582
NCBI chr19:40,875,439...40,882,231
Ensembl chr19:40,875,439...40,882,752
G
CYP2B6
cytochrome P450 family 2 subfamily B member 6
decreases expression
ISO
Methylcholanthrene results in decreased expression of CYP2B3 mRNA Methylcholanthrene results in decreased expression of CYP2B10 mRNA
CTD
PMID:11328961 PMID:30503582
NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
G
CYP2C18
cytochrome P450 family 2 subfamily C member 18
decreases expression multiple interactions increases expression
ISO
Methylcholanthrene results in decreased expression of CYP2C11 mRNA Methylcholanthrene promotes the reaction [CYP2C11 protein results in increased oxidation of Toluene] Methylcholanthrene results in increased expression of CYP2C11 mRNA
CTD
PMID:1994898 PMID:10476907 PMID:22978700 PMID:23273579
NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
G
CYP2C8
cytochrome P450 family 2 subfamily C member 8
increases expression
ISO
Methylcholanthrene results in increased expression of CYP2C29 mRNA
CTD
PMID:30503582
NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
G
CYP2D6
cytochrome P450 family 2 subfamily D member 6
increases expression
ISO
Methylcholanthrene results in increased expression of CYP2D4 mRNA
CTD
PMID:11328961
NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
G
CYP2E1
cytochrome P450 family 2 subfamily E member 1
multiple interactions increases expression decreases expression decreases activity
ISO EXP
[Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA; [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein; [Acetone co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein; [Acetone co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein; [Methylcholanthrene results in decreased expression of CYP2E1 protein] which affects the metabolism of Benzene; [protocatechuic acid co-treated with Methylcholanthrene] results in decreased activity of CYP2E1 protein; [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA; [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein; [pyridine co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein; [pyridine co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein; Methylcholanthrene promotes the reaction [CYP2E1 protein results in increased oxidation of Toluene] 3-methylcholanthrene increases expression of mRNA, protein in rat heart Methylcholanthrene results in decreased expression of CYP2E1 mRNA Methylcholanthrene results in increased expression of CYP2E1 mRNA; Methylcholanthrene results in increased expression of CYP2E1 protein Methylcholanthrene results in decreased expression of CYP2E1 mRNA; Methylcholanthrene results in decreased expression of CYP2E1 protein Methylcholanthrene results in decreased activity of CYP2E1 protein
CTD RGD
PMID:1994898 PMID:3113478 PMID:7493548 PMID:8734847 PMID:9118891 PMID:10476907 PMID:15302093 PMID:19889059 PMID:23273579 PMID:28673560 PMID:30503582 PMID:19889059 More...
RGD:401794453
NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
G
CYP2S1
cytochrome P450 family 2 subfamily S member 1
increases expression
ISO
Methylcholanthrene results in increased expression of CYP2S1 mRNA
CTD
PMID:19883719
NCBI chr19:41,193,219...41,207,539
Ensembl chr19:41,193,210...41,207,539
G
CYP3A4
cytochrome P450 family 3 subfamily A member 4
decreases expression increases expression multiple interactions
EXP ISO
Methylcholanthrene results in decreased expression of CYP3A4 protein Methylcholanthrene results in increased expression of CYP3A2 mRNA Dactinomycin inhibits the reaction [Methylcholanthrene results in increased expression of CYP3A2 mRNA] [Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP3A4 mRNA; Methylcholanthrene results in decreased expression of and results in decreased activity of CYP3A4 protein
CTD
PMID:10640517 PMID:11181506 PMID:23846873 PMID:24999631
NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
G
CYP3A5
cytochrome P450 family 3 subfamily A member 5
multiple interactions increases expression
EXP
AHR protein affects the reaction [Methylcholanthrene results in increased expression of CYP3A5 mRNA]
CTD
PMID:33408298
NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
G
CYP3A7-CYP3A51P
CYP3A7-CYP3A51P readthrough
decreases expression
ISO
Methylcholanthrene results in decreased expression of CYP3A41A protein
CTD
PMID:23846873
NCBI chr 7:99,684,677...99,735,196
Ensembl chr 7:99,684,957...99,735,102
G
CYP4B1
cytochrome P450 family 4 subfamily B member 1
increases expression
ISO
Methylcholanthrene results in increased expression of CYP4B1 mRNA
CTD
PMID:23273579
NCBI chr 1:46,799,046...46,819,413
Ensembl chr 1:46,757,838...46,819,413
G
CYP4F8
cytochrome P450 family 4 subfamily F member 8
decreases expression
ISO
Methylcholanthrene results in decreased expression of CYP4F6 mRNA
CTD
PMID:11328961
NCBI chr19:15,615,218...15,630,639
Ensembl chr19:15,615,218...15,630,639
G
DAB2
DAB adaptor protein 2
increases expression
ISO
Methylcholanthrene results in increased expression of DAB2 mRNA
CTD
PMID:20713471
NCBI chr 5:39,371,677...39,424,980
Ensembl chr 5:39,371,675...39,462,300
G
DACT1
dishevelled binding antagonist of beta catenin 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of DACT1 mRNA
CTD
PMID:20713471
NCBI chr14:58,634,061...58,648,321
Ensembl chr14:58,633,967...58,648,321
G
DAPK1
death associated protein kinase 1
multiple interactions
ISO
[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of DAPK1 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of DAPK1 promoter [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DAPK1 mRNA
CTD
PMID:20970405 PMID:23519560
NCBI chr 9:87,497,228...87,708,634
Ensembl chr 9:87,497,228...87,708,634
G
DAPK2
death associated protein kinase 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DAPK2 mRNA
CTD
PMID:23519560
NCBI chr15:63,907,036...64,046,485
Ensembl chr15:63,907,036...64,072,033
G
DAZL
deleted in azoospermia like
decreases expression
ISO
Methylcholanthrene results in decreased expression of DAZL mRNA
CTD
PMID:35487396
NCBI chr 3:16,586,792...16,605,423
Ensembl chr 3:16,586,792...16,670,306
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DBN1
drebrin 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of DBN1 mRNA
CTD
PMID:20713471
NCBI chr 5:177,456,610...177,473,634
Ensembl chr 5:177,456,608...177,474,401
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DCK
deoxycytidine kinase
increases expression
ISO
Methylcholanthrene results in increased expression of DCK mRNA
CTD
PMID:20713471
NCBI chr 4:70,993,649...71,030,914
Ensembl chr 4:70,992,538...71,030,914
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DCLK1
doublecortin like kinase 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of DCLK1 mRNA
CTD
PMID:20713471
NCBI chr13:35,768,652...36,131,939
Ensembl chr13:35,768,652...36,131,382
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DDR2
discoidin domain receptor tyrosine kinase 2
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of DDR2 mRNA alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDR2 mRNA]
CTD
PMID:29094188
NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405
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DDX17
DEAD-box helicase 17
increases expression
ISO
Methylcholanthrene results in increased expression of DDX17 mRNA
CTD
PMID:25926378
NCBI chr22:38,483,438...38,506,311
Ensembl chr22:38,483,438...38,507,660
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DDX4
DEAD-box helicase 4
decreases expression
ISO
Methylcholanthrene results in decreased expression of DDX4 mRNA
CTD
PMID:35487396
NCBI chr 5:55,738,061...55,817,157
Ensembl chr 5:55,738,017...55,817,157
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DDX5
DEAD-box helicase 5
multiple interactions increases expression
ISO
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDX5 mRNA]
CTD
PMID:29094188
NCBI chr17:64,498,254...64,506,866
Ensembl chr17:64,498,254...64,508,199
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DEGS1
delta 4-desaturase, sphingolipid 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to DEGS1 promoter]
CTD
PMID:20348232
NCBI chr 1:224,183,240...224,193,441
Ensembl chr 1:224,175,756...224,193,441
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DEPDC1
DEP domain containing 1
increases expression
ISO
Methylcholanthrene results in increased expression of DEPDC1A mRNA
CTD
PMID:20713471
NCBI chr 1:68,474,152...68,497,082
Ensembl chr 1:68,474,152...68,497,221
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DEPDC1B
DEP domain containing 1B
increases expression
ISO
Methylcholanthrene results in increased expression of DEPDC1B mRNA
CTD
PMID:20713471
NCBI chr 5:60,596,912...60,700,166
Ensembl chr 5:60,596,912...60,700,190
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DEPTOR
DEP domain containing MTOR interacting protein
decreases expression
ISO
Methylcholanthrene results in decreased expression of DEPTOR mRNA
CTD
PMID:20713471
NCBI chr 8:119,873,722...120,050,918
Ensembl chr 8:119,873,717...120,050,918
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DHFR
dihydrofolate reductase
increases expression
ISO
Methylcholanthrene results in increased expression of DHFR mRNA
CTD
PMID:20713471
NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983
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DIAPH1
diaphanous related formin 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to DIAPH1 promoter]
CTD
PMID:20348232
NCBI chr 5:141,515,021...141,619,000
Ensembl chr 5:141,515,016...141,619,055
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DLGAP5
DLG associated protein 5
increases expression
ISO
Methylcholanthrene results in increased expression of DLGAP5 mRNA
CTD
PMID:20713471
NCBI chr14:55,148,135...55,191,585
Ensembl chr14:55,148,112...55,191,608
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DLL1
delta like canonical Notch ligand 1
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of DLL1 mRNA alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DLL1 mRNA]
CTD
PMID:29094188
NCBI chr 6:170,282,206...170,291,078
Ensembl chr 6:170,282,206...170,306,565
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DMP1
dentin matrix acidic phosphoprotein 1
increases expression
ISO
Methylcholanthrene results in increased expression of DMP1 mRNA
CTD
PMID:20713471
NCBI chr 4:87,650,280...87,664,357
Ensembl chr 4:87,650,280...87,664,361
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DNAJB6
DnaJ heat shock protein family (Hsp40) member B6
multiple interactions increases expression increases acetylation increases methylation
ISO
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of DNAJB6 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DNAJB6 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of DNAJB6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]
CTD
PMID:29094188
NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439
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DNAJC9
DnaJ heat shock protein family (Hsp40) member C9
increases expression
ISO
Methylcholanthrene results in increased expression of DNAJC9 mRNA
CTD
PMID:20713471
NCBI chr10:73,232,272...73,247,255
Ensembl chr10:73,183,362...73,247,255
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DNMT1
DNA methyltransferase 1
multiple interactions
ISO
[Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT1 protein
CTD
PMID:21163286
NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
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DNMT3A
DNA methyltransferase 3 alpha
multiple interactions
ISO
[Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT3A protein
CTD
PMID:21163286
NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
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DTL
denticleless E3 ubiquitin protein ligase homolog
increases expression
ISO
Methylcholanthrene results in increased expression of DTL mRNA
CTD
PMID:20713471
NCBI chr 1:212,035,748...212,105,013
Ensembl chr 1:212,035,553...212,107,400
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DTNA
dystrobrevin alpha
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to DTNA promoter]
CTD
PMID:20348232
NCBI chr18:34,493,312...34,891,844
Ensembl chr18:34,493,291...34,891,844
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DUSP14
dual specificity phosphatase 14
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to DUSP14 promoter]
CTD
PMID:20348232
NCBI chr17:37,488,566...37,513,498
Ensembl chr17:37,489,891...37,513,501
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DUSP4
dual specificity phosphatase 4
increases expression
ISO
Methylcholanthrene results in increased expression of DUSP4 mRNA
CTD
PMID:20713471
NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684
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DUSP6
dual specificity phosphatase 6
increases expression
ISO
Methylcholanthrene results in increased expression of DUSP6 mRNA
CTD
PMID:20713471
NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501
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DUT
deoxyuridine triphosphatase
increases expression
ISO
Methylcholanthrene results in increased expression of DUT mRNA
CTD
PMID:20713471
NCBI chr15:48,331,095...48,343,373
Ensembl chr15:48,331,011...48,343,373
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DYRK2
dual specificity tyrosine phosphorylation regulated kinase 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of DYRK2 mRNA
CTD
PMID:20713471
NCBI chr12:67,648,745...67,665,406
Ensembl chr12:67,648,338...67,665,406
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E2F7
E2F transcription factor 7
increases expression
ISO
Methylcholanthrene results in increased expression of E2F7 mRNA
CTD
PMID:20713471
NCBI chr12:77,021,251...77,065,569
Ensembl chr12:77,021,248...77,065,569
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E2F8
E2F transcription factor 8
increases expression
ISO
Methylcholanthrene results in increased expression of E2F8 mRNA
CTD
PMID:20713471
NCBI chr11:19,224,063...19,241,655
Ensembl chr11:19,224,063...19,241,620
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ECM1
extracellular matrix protein 1
increases expression
ISO
Methylcholanthrene results in increased expression of ECM1 mRNA
CTD
PMID:20713471
NCBI chr 1:150,508,109...150,513,789
Ensembl chr 1:150,508,062...150,513,789
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ECT2
epithelial cell transforming 2
increases expression
ISO
Methylcholanthrene results in increased expression of ECT2 mRNA
CTD
PMID:20713471
NCBI chr 3:172,750,726...172,829,265
Ensembl chr 3:172,750,682...172,821,474
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EFNA5
ephrin A5
decreases expression
ISO
Methylcholanthrene results in decreased expression of EFNA5 mRNA
CTD
PMID:20713471
NCBI chr 5:107,376,894...107,670,937
Ensembl chr 5:107,376,894...107,670,937
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EFNB1
ephrin B1
increases expression
ISO
Methylcholanthrene results in increased expression of EFNB1 mRNA
CTD
PMID:20713471
NCBI chr X:68,829,021...68,842,160
Ensembl chr X:68,829,021...68,842,160
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EGFR
epidermal growth factor receptor
decreases expression
ISO
Methylcholanthrene results in decreased expression of EGFR mRNA
CTD
PMID:29094188
NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
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EGR2
early growth response 2
increases expression
ISO
Methylcholanthrene results in increased expression of EGR2 mRNA
CTD
PMID:29554273
NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167
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EGR3
early growth response 3
increases expression
ISO
Methylcholanthrene results in increased expression of EGR3 mRNA
CTD
PMID:20713471
NCBI chr 8:22,687,659...22,693,480
Ensembl chr 8:22,687,659...22,693,480
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EHD3
EH domain containing 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to EHD3 promoter]
CTD
PMID:20348232
NCBI chr 2:31,234,152...31,269,451
Ensembl chr 2:31,234,152...31,269,451
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EIF2B2
eukaryotic translation initiation factor 2B subunit beta
increases expression
ISO
Methylcholanthrene results in increased expression of EIF2B2 mRNA
CTD
PMID:20713471
NCBI chr14:75,002,921...75,012,366
Ensembl chr14:75,002,921...75,012,366
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EIF4E1B
eukaryotic translation initiation factor 4E family member 1B
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF4E1B mRNA
CTD
PMID:23519560
NCBI chr 5:176,630,675...176,646,644
Ensembl chr 5:176,630,618...176,646,644
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EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
increases expression
ISO
Methylcholanthrene results in increased expression of EIF4EBP2 mRNA
CTD
PMID:25926378
NCBI chr10:70,404,145...70,428,618
Ensembl chr10:70,404,145...70,428,618
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ELMO1
engulfment and cell motility 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ELMO1 mRNA
CTD
PMID:23519560
NCBI chr 7:36,852,906...37,449,326
Ensembl chr 7:36,852,906...37,449,223
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ELOVL3
ELOVL fatty acid elongase 3
increases expression
ISO
Methylcholanthrene results in increased expression of ELOVL3 mRNA
CTD
PMID:25926378
NCBI chr10:102,224,767...102,229,589
Ensembl chr10:102,226,299...102,229,589
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EME1
essential meiotic structure-specific endonuclease 1
increases expression
ISO
Methylcholanthrene results in increased expression of EME1 mRNA
CTD
PMID:20713471
NCBI chr17:50,373,229...50,381,483
Ensembl chr17:50,373,220...50,381,483
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EMP1
epithelial membrane protein 1
increases expression
ISO
Methylcholanthrene results in increased expression of EMP1 mRNA
CTD
PMID:20713471
NCBI chr12:13,196,726...13,219,941
Ensembl chr12:13,196,723...13,219,941
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ENPEP
glutamyl aminopeptidase
decreases expression
ISO
Methylcholanthrene results in decreased expression of ENPEP mRNA
CTD
PMID:20713471
NCBI chr 4:110,476,155...110,565,285
Ensembl chr 4:110,365,733...110,565,285
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ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of ENPP2 mRNA
CTD
PMID:20713471
NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453
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EPAS1
endothelial PAS domain protein 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA
CTD
PMID:23519560
NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
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EPHB6
EPH receptor B6
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EPHB6 mRNA
CTD
PMID:23519560
NCBI chr 7:142,855,076...142,871,093
Ensembl chr 7:142,855,061...142,871,094
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EPHX1
epoxide hydrolase 1
increases activity increases expression
ISO
Methylcholanthrene results in increased activity of EPHX1 protein Methylcholanthrene results in increased expression of EPHX1 mRNA
CTD
PMID:3621371 PMID:23273579
NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
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EPHX2
epoxide hydrolase 2
increases activity increases expression decreases activity
ISO
Methylcholanthrene results in increased activity of EPHX2 protein 3-methylcholanthrene increases expression of mRNA, protein in rat heart Methylcholanthrene results in decreased activity of EPHX2 protein Methylcholanthrene results in increased expression of EPHX2 mRNA; Methylcholanthrene results in increased expression of EPHX2 protein
CTD RGD
PMID:3621371 PMID:19889059 PMID:19889059
RGD:401794453
NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
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EPS15
epidermal growth factor receptor pathway substrate 15
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to EPS15 promoter]
CTD
PMID:20348232
NCBI chr 1:51,354,263...51,519,266
Ensembl chr 1:51,354,263...51,519,328
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EPS8
EGFR pathway substrate 8, signaling adaptor
increases expression
ISO
Methylcholanthrene results in increased expression of EPS8 mRNA
CTD
PMID:20713471
NCBI chr12:15,620,134...15,789,388
Ensembl chr12:15,620,134...15,882,329
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ERCC6
ERCC excision repair 6, chromatin remodeling factor
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ERCC6 promoter]
CTD
PMID:20348232
NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538
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ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase
increases expression
ISO
Methylcholanthrene results in increased expression of ERCC6L mRNA
CTD
PMID:20713471
NCBI chr X:72,204,665...72,239,027
Ensembl chr X:72,204,657...72,239,027
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EREG
epiregulin
increases expression
ISO
Methylcholanthrene results in increased expression of EREG mRNA
CTD
PMID:20713471
NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749
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ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
increases expression
ISO
Methylcholanthrene results in increased expression of ESCO2 mRNA
CTD
PMID:20713471
NCBI chr 8:27,771,974...27,819,660
Ensembl chr 8:27,771,949...27,812,640
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ESPL1
extra spindle pole bodies like 1, separase
increases expression
ISO
Methylcholanthrene results in increased expression of ESPL1 mRNA
CTD
PMID:20713471
NCBI chr12:53,268,299...53,293,638
Ensembl chr12:53,268,299...53,293,638
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ESR1
estrogen receptor 1
multiple interactions decreases expression increases expression increases activity affects binding
EXP ISO
fulvestrant inhibits the reaction [Methylcholanthrene results in increased expression of ESR1 mRNA]; Methylcholanthrene binds to and results in increased activity of ESR1 protein; Methylcholanthrene promotes the reaction [AHR protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [ESR1 protein binds to CYP1A1 promoter] Methylcholanthrene results in decreased expression of ESR1 mRNA alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ESR1 mRNA] Methylcholanthrene results in increased activity of ESR1 protein Methylcholanthrene binds to ESR1 protein
CTD
PMID:16257430 PMID:16489053 PMID:16972788 PMID:20348232 PMID:23273579 PMID:29094188 More...
NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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ETV1
ETS variant transcription factor 1
increases expression
ISO
Methylcholanthrene results in increased expression of ETV1 mRNA
CTD
PMID:20713471
NCBI chr 7:13,891,229...13,991,425
Ensembl chr 7:13,891,229...13,991,425
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ETV5
ETS variant transcription factor 5
increases expression
ISO
Methylcholanthrene results in increased expression of ETV5 mRNA
CTD
PMID:20713471
NCBI chr 3:186,046,314...186,109,089
Ensembl chr 3:186,046,314...186,110,318
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EXO1
exonuclease 1
increases expression
ISO
Methylcholanthrene results in increased expression of EXO1 mRNA
CTD
PMID:20713471
NCBI chr 1:241,847,986...241,889,939
Ensembl chr 1:241,847,967...241,895,148
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EXOSC9
exosome component 9
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to EXOSC9 promoter]
CTD
PMID:20348232
NCBI chr 4:121,801,323...121,817,021
Ensembl chr 4:121,801,318...121,817,021
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F11R
F11 receptor
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of F11R mRNA
CTD
PMID:23519560
NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175
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FABP4
fatty acid binding protein 4
decreases expression multiple interactions
ISO
Methylcholanthrene results in decreased expression of FABP4 mRNA [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of FABP4 mRNA
CTD
PMID:25926378
NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
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FAS
Fas cell surface death receptor
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FAS mRNA
CTD
PMID:23519560
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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FCAR
Fc alpha receptor
increases expression
EXP
Methylcholanthrene results in increased expression of FCAR mRNA
CTD
PMID:21911031
NCBI chr19:54,874,235...54,891,420
Ensembl chr19:54,874,235...54,891,420
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FCHSD2
FCH and double SH3 domains 2
increases expression
ISO
Methylcholanthrene results in increased expression of FCHSD2 mRNA
CTD
PMID:20713471
NCBI chr11:72,836,745...73,142,318
Ensembl chr11:72,836,745...73,142,318
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FCRL5
Fc receptor like 5
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of FCRL5 mRNA
CTD
PMID:25926378
NCBI chr 1:157,513,377...157,552,515
Ensembl chr 1:157,513,377...157,552,515
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FDPS
farnesyl diphosphate synthase
decreases expression
ISO
Methylcholanthrene results in decreased expression of FDPS mRNA
CTD
PMID:20713471
NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666
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FDXR
ferredoxin reductase
increases expression
EXP
Methylcholanthrene results in increased expression of FDXR mRNA
CTD
PMID:22100608
NCBI chr17:74,862,497...74,872,994
Ensembl chr17:74,862,497...74,873,031
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FGF1
fibroblast growth factor 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF1 mRNA
CTD
PMID:23519560
NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
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FGF10
fibroblast growth factor 10
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF10 mRNA
CTD
PMID:23519560
NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706
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FGF18
fibroblast growth factor 18
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF18 mRNA
CTD
PMID:23519560
NCBI chr 5:171,419,647...171,457,626
Ensembl chr 5:171,419,647...171,457,626
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FGF7
fibroblast growth factor 7
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF7 mRNA
CTD
PMID:23519560
NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775
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FGFR1
fibroblast growth factor receptor 1
increases expression
ISO
Methylcholanthrene results in increased expression of FGFR1 mRNA
CTD
PMID:20713471 PMID:29554273
NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
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FGFR2
fibroblast growth factor receptor 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGFR2 mRNA
CTD
PMID:23519560
NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
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FHIT
fragile histidine triad diadenosine triphosphatase
multiple interactions decreases expression
ISO EXP
[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of FHIT protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of FHIT promoter Methylcholanthrene results in decreased expression of FHIT mRNA
CTD
PMID:20970405 PMID:22100608
NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459
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FIGNL1
fidgetin like 1
increases expression
ISO
Methylcholanthrene results in increased expression of FIGNL1 mRNA
CTD
PMID:20713471
NCBI chr 7:50,444,133...50,450,350
Ensembl chr 7:50,444,128...50,450,390
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FMO2
flavin containing dimethylaniline monoxygenase 2
increases expression
ISO
Methylcholanthrene results in increased expression of FMO2 mRNA
CTD
PMID:20570689
NCBI chr 1:171,185,208...171,212,686
Ensembl chr 1:171,185,249...171,212,686
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FMO3
flavin containing dimethylaniline monoxygenase 3
multiple interactions decreases expression increases expression
ISO
AHR protein affects the reaction [Methylcholanthrene results in increased expression of FMO3 mRNA]; Methylcholanthrene promotes the reaction [TRP53 protein binds to FMO3 5' UTR] Methylcholanthrene results in decreased expression of FMO3 mRNA
CTD
PMID:20570689 PMID:23273579 PMID:23846873 PMID:25926378
NCBI chr 1:171,090,905...171,117,819
Ensembl chr 1:171,090,901...171,117,819
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FMOD
fibromodulin
decreases expression
ISO
Methylcholanthrene results in decreased expression of FMOD mRNA
CTD
PMID:20713471
NCBI chr 1:203,340,628...203,351,122
Ensembl chr 1:203,340,628...203,351,758
G
FOSL1
FOS like 1, AP-1 transcription factor subunit
increases expression
ISO
Methylcholanthrene results in increased expression of FOSL1 mRNA
CTD
PMID:20713471
NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
G
FOXM1
forkhead box M1
affects response to substance
ISO
FOXM1 protein affects the susceptibility to Methylcholanthrene
CTD
PMID:18345025 PMID:19672312
NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174
G
FOXN1
forkhead box N1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to FOXN1 promoter]
CTD
PMID:20348232
NCBI chr17:28,506,348...28,538,900
Ensembl chr17:28,506,243...28,538,900
G
FOXN3
forkhead box N3
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of FOXN3 mRNA alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of FOXN3 mRNA]
CTD
PMID:29094188
NCBI chr14:89,156,177...89,619,165
Ensembl chr14:89,124,871...89,619,149
G
FOXN4
forkhead box N4
multiple interactions increases expression
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of FOXN4 mRNA]
CTD
PMID:20348232
NCBI chr12:109,277,978...109,309,284
Ensembl chr12:109,277,978...109,309,284
G
FOXO3
forkhead box O3
multiple interactions
ISO
[Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of FOXO3 mRNA
CTD
PMID:29094188
NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
G
FREM2
FRAS1 related extracellular matrix 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to FREM2 promoter]
CTD
PMID:20348232
NCBI chr13:38,687,077...38,887,131
Ensembl chr13:38,687,077...38,887,131
G
FRYL
FRY like transcription coactivator
increases expression
ISO
Methylcholanthrene results in increased expression of FRYL mRNA
CTD
PMID:20713471
NCBI chr 4:48,497,357...48,780,279
Ensembl chr 4:48,497,357...48,780,322
G
FST
follistatin
decreases expression
ISO
Methylcholanthrene results in decreased expression of FST mRNA
CTD
PMID:20713471
NCBI chr 5:53,480,629...53,487,134
Ensembl chr 5:53,480,626...53,487,134
G
FSTL1
follistatin like 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of FSTL1 mRNA
CTD
PMID:20713471
NCBI chr 3:120,392,293...120,450,992
Ensembl chr 3:120,392,293...120,451,016
G
FUT8
fucosyltransferase 8
increases expression
ISO
Methylcholanthrene results in increased expression of FUT8 mRNA
CTD
PMID:20713471
NCBI chr14:65,356,842...65,744,121
Ensembl chr14:65,410,592...65,744,121
G
FXYD5
FXYD domain containing ion transport regulator 5
increases expression
ISO
Methylcholanthrene results in increased expression of FXYD5 mRNA
CTD
PMID:20713471
NCBI chr19:35,154,735...35,169,881
Ensembl chr19:35,154,730...35,169,881
G
FYN
FYN proto-oncogene, Src family tyrosine kinase
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FYN mRNA
CTD
PMID:23519560
NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
G
GAB2
GRB2 associated binding protein 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of GAB2 mRNA
CTD
PMID:20713471
NCBI chr11:78,215,293...78,417,820
Ensembl chr11:78,215,293...78,418,348
G
GABRA3
gamma-aminobutyric acid type A receptor subunit alpha3
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GABRA3 mRNA
CTD
PMID:23519560
NCBI chr X:152,166,234...152,451,315
Ensembl chr X:152,166,234...152,451,315
G
GADD45A
growth arrest and DNA damage inducible alpha
decreases expression
ISO
Methylcholanthrene results in decreased expression of GADD45A mRNA
CTD
PMID:20713471
NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
G
GALNT15
polypeptide N-acetylgalactosaminyltransferase 15
increases expression
ISO
Methylcholanthrene results in increased expression of GALNT15 mRNA
CTD
PMID:20713471
NCBI chr 3:16,174,680...16,248,224
Ensembl chr 3:16,174,680...16,231,992
G
GALNT18
polypeptide N-acetylgalactosaminyltransferase 18
decreases expression
ISO
Methylcholanthrene results in decreased expression of GALNT18 mRNA
CTD
PMID:20713471
NCBI chr11:11,270,877...11,622,005
Ensembl chr11:11,270,877...11,622,005
G
GALNT7
polypeptide N-acetylgalactosaminyltransferase 7
increases expression
ISO
Methylcholanthrene results in increased expression of GALNT7 mRNA
CTD
PMID:20713471
NCBI chr 4:173,168,811...173,323,967
Ensembl chr 4:173,168,811...173,323,967
G
GAS2L3
growth arrest specific 2 like 3
increases expression
ISO
Methylcholanthrene results in increased expression of GAS2L3 mRNA
CTD
PMID:20713471
NCBI chr12:100,573,684...100,628,288
Ensembl chr12:100,573,683...100,628,288
G
GATA6
GATA binding protein 6
multiple interactions increases activity
ISO
Methylcholanthrene promotes the reaction [GATA6 protein binds to KRAS exon] Methylcholanthrene results in increased activity of GATA6 protein
CTD
PMID:16271038
NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
G
GCAT
glycine C-acetyltransferase
increases expression
ISO
Methylcholanthrene results in increased expression of GCAT mRNA
CTD
PMID:20713471
NCBI chr22:37,807,934...37,817,183
Ensembl chr22:37,807,905...37,817,176
G
GCH1
GTP cyclohydrolase 1
increases expression
ISO
Methylcholanthrene results in increased expression of GCH1 mRNA
CTD
PMID:20713471
NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826
G
GCHFR
GTP cyclohydrolase I feedback regulator
increases expression
ISO
Methylcholanthrene results in increased expression of GCHFR mRNA
CTD
PMID:20713471
NCBI chr15:40,764,068...40,767,708
Ensembl chr15:40,764,068...40,767,708
G
GDF9
growth differentiation factor 9
multiple interactions
ISO
[Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of GDF9 mRNA
CTD
PMID:29094188
NCBI chr 5:132,861,185...132,866,651
Ensembl chr 5:132,861,181...132,866,884
G
GDNF
glial cell derived neurotrophic factor
decreases expression
ISO
Methylcholanthrene results in decreased expression of GDNF mRNA
CTD
PMID:35487396
NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041
G
GDPD4
glycerophosphodiester phosphodiesterase domain containing 4
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to GDPD4 promoter]
CTD
PMID:20348232
NCBI chr11:77,216,558...77,301,699
Ensembl chr11:77,216,558...77,301,687
G
GH1
growth hormone 1
decreases activity
ISO
Methylcholanthrene results in decreased activity of GH1 protein
CTD
PMID:22978700
NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
G
GHR
growth hormone receptor
decreases expression increases expression
ISO
Methylcholanthrene results in decreased expression of GHR mRNA Methylcholanthrene results in increased expression of GHR protein
CTD
PMID:22978700 PMID:23169610
NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878
G
GINS3
GINS complex subunit 3
increases expression
ISO
Methylcholanthrene results in increased expression of GINS3 mRNA
CTD
PMID:20713471
NCBI chr16:58,392,471...58,406,147
Ensembl chr16:58,295,080...58,406,147
G
GINS4
GINS complex subunit 4
increases expression
ISO
Methylcholanthrene results in increased expression of GINS4 mRNA
CTD
PMID:20713471
NCBI chr 8:41,529,261...41,545,030
Ensembl chr 8:41,529,218...41,545,030
G
GJA1
gap junction protein alpha 1
increases expression
ISO
Methylcholanthrene results in increased expression of GJA1 mRNA
CTD
PMID:20713471
NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
G
GMNN
geminin DNA replication inhibitor
increases expression
ISO
Methylcholanthrene results in increased expression of GMNN mRNA
CTD
PMID:20713471
NCBI chr 6:24,774,937...24,786,099
Ensembl chr 6:24,774,931...24,786,099
G
GNB4
G protein subunit beta 4
increases expression
ISO
Methylcholanthrene results in increased expression of GNB4 mRNA
CTD
PMID:20713471
NCBI chr 3:179,396,088...179,527,798
Ensembl chr 3:179,396,088...179,451,476
G
GNMT
glycine N-methyltransferase
decreases expression multiple interactions
EXP ISO
Methylcholanthrene results in decreased expression of GNMT mRNA [Methylcholanthrene co-treated with GNMT protein] results in increased expression of CYP1A1 mRNA
CTD
PMID:9261130 PMID:22100608
NCBI chr 6:42,960,754...42,963,880
Ensembl chr 6:42,960,754...42,963,880
G
GPC1
glypican 1
increases expression
ISO
Methylcholanthrene results in increased expression of GPC1 mRNA
CTD
PMID:20713471
NCBI chr 2:240,435,663...240,468,076
Ensembl chr 2:240,435,663...240,468,076
G
GPCPD1
glycerophosphocholine phosphodiesterase 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of GPCPD1 mRNA
CTD
PMID:20713471
NCBI chr20:5,544,439...5,611,006
Ensembl chr20:5,544,439...5,611,006
G
GPHB5
glycoprotein hormone subunit beta 5
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to GPHB5 promoter]
CTD
PMID:20348232
NCBI chr14:63,312,835...63,318,935
Ensembl chr14:63,312,835...63,318,935
G
GPNMB
glycoprotein nmb
increases expression
ISO
Methylcholanthrene results in increased expression of GPNMB mRNA
CTD
PMID:20713471
NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108
G
GPX1
glutathione peroxidase 1
increases expression
ISO
Methylcholanthrene results in increased expression of GPX1 mRNA
CTD
PMID:23273579 PMID:23712962
NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
G
GREB1
growth regulating estrogen receptor binding 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to GREB1 promoter]
CTD
PMID:20348232
NCBI chr 2:11,482,888...11,642,788
Ensembl chr 2:11,482,341...11,642,788
G
GRIA3
glutamate ionotropic receptor AMPA type subunit 3
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIA3 mRNA
CTD
PMID:23519560
NCBI chr X:123,184,278...123,490,915
Ensembl chr X:123,184,153...123,490,915
G
GRIK4
glutamate ionotropic receptor kainate type subunit 4
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to GRIK4 promoter]
CTD
PMID:20348232
NCBI chr11:120,511,748...120,988,906
Ensembl chr11:120,511,746...120,988,906
G
GRIK5
glutamate ionotropic receptor kainate type subunit 5
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIK5 mRNA
CTD
PMID:23519560
NCBI chr19:41,998,324...42,070,206
Ensembl chr19:41,998,321...42,070,206
G
GSDMC
gasdermin C
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to GSDMC promoter]
CTD
PMID:20348232
NCBI chr 8:129,705,435...129,786,624
Ensembl chr 8:129,748,196...129,786,624
G
GSDMD
gasdermin D
increases expression
ISO
Methylcholanthrene results in increased expression of GSDMD mRNA
CTD
PMID:20713471
NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062
G
GSDME
gasdermin E
increases expression
ISO
Methylcholanthrene results in increased expression of GSDME mRNA
CTD
PMID:20713471
NCBI chr 7:24,698,355...24,795,539
Ensembl chr 7:24,698,355...24,757,940
G
GSR
glutathione-disulfide reductase
increases activity increases expression
ISO
Methylcholanthrene results in increased activity of GSR protein Methylcholanthrene results in increased expression of GSR mRNA
CTD
PMID:23712962
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
G
GSS
glutathione synthetase
increases activity increases expression
ISO
Methylcholanthrene results in increased activity of GSS protein Methylcholanthrene results in increased expression of GSS mRNA
CTD
PMID:23712962
NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027
G
GSTA2
glutathione S-transferase alpha 2
decreases expression increases expression
ISO
Methylcholanthrene results in decreased expression of GSTA2 mRNA Methylcholanthrene results in increased expression of GSTA2 mRNA
CTD
PMID:10476907 PMID:11328961 PMID:23273579
NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475
G
GSTA3
glutathione S-transferase alpha 3
decreases expression
ISO
Methylcholanthrene results in decreased expression of GSTA1 mRNA
CTD
PMID:23712962
NCBI chr 6:52,896,646...52,909,698
Ensembl chr 6:52,896,639...52,909,698
G
GSTK1
glutathione S-transferase kappa 1
increases expression
ISO
Methylcholanthrene results in increased expression of GSTK1 mRNA
CTD
PMID:23273579
NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854
G
GSTM1
glutathione S-transferase mu 1
increases expression
ISO
Methylcholanthrene results in increased expression of GSTM1 mRNA
CTD
PMID:11328961 PMID:23273579
NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
G
GSTP1
glutathione S-transferase pi 1
increases expression
ISO
Methylcholanthrene results in increased expression of GSTP1 mRNA
CTD
PMID:19118567 PMID:23273579
NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
G
GTSE1
G2 and S-phase expressed 1
increases expression
ISO
Methylcholanthrene results in increased expression of GTSE1 mRNA
CTD
PMID:20713471
NCBI chr22:46,296,870...46,330,810
Ensembl chr22:46,296,870...46,330,810
G
GULP1
GULP PTB domain containing engulfment adaptor 1
increases expression
EXP
Methylcholanthrene results in increased expression of GULP1 mRNA
CTD
PMID:23397585
NCBI chr 2:188,291,874...188,595,926
Ensembl chr 2:188,291,669...188,595,931
G
H2BC1
H2B clustered histone 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to H2BC1 promoter]
CTD
PMID:20348232
NCBI chr 6:25,726,777...25,727,345
Ensembl chr 6:25,726,777...25,727,345
G
H2BC21
H2B clustered histone 21
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to H2BC21 promoter]
CTD
PMID:20348232
NCBI chr 1:149,884,459...149,886,682
Ensembl chr 1:149,884,459...149,886,682
G
H3-3B
H3.3 histone B
decreases expression
ISO
Methylcholanthrene results in decreased expression of H3F3B mRNA
CTD
PMID:20713471
NCBI chr17:75,776,434...75,779,779
Ensembl chr17:75,776,434...75,785,893
G
HACD4
3-hydroxyacyl-CoA dehydratase 4
increases expression
ISO
Methylcholanthrene results in increased expression of HACD4 mRNA
CTD
PMID:20713471
NCBI chr 9:20,999,509...21,031,640
Ensembl chr 9:20,999,509...21,031,640
G
HASPIN
histone H3 associated protein kinase
increases expression
ISO
Methylcholanthrene results in increased expression of HASPIN mRNA
CTD
PMID:20713471
NCBI chr17:3,723,903...3,726,699
Ensembl chr17:3,723,903...3,726,699
G
HBA1
hemoglobin subunit alpha 1
increases expression
ISO
Methylcholanthrene results in increased expression of HBA-A1 mRNA
CTD
PMID:20713471
NCBI chr16:176,680...177,522
Ensembl chr16:176,680...177,522
G
HCK
HCK proto-oncogene, Src family tyrosine kinase
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HCK mRNA
CTD
PMID:23519560
NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856
G
HCRTR2
hypocretin receptor 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to HCRTR2 promoter]
CTD
PMID:20348232
NCBI chr 6:55,106,469...55,284,713
Ensembl chr 6:55,106,460...55,282,617
G
HDAC11
histone deacetylase 11
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to HDAC11 promoter]
CTD
PMID:20348232
NCBI chr 3:13,480,306...13,506,416
Ensembl chr 3:13,479,724...13,506,424
G
HDAC5
histone deacetylase 5
increases expression
ISO
Methylcholanthrene results in increased expression of HDAC5 mRNA
CTD
PMID:29554273
NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702
G
HEPH
hephaestin
increases expression
ISO
Methylcholanthrene results in increased expression of HEPH mRNA
CTD
PMID:20713471
NCBI chr X:66,162,671...66,268,863
Ensembl chr X:66,162,671...66,268,867
G
HES1
hes family bHLH transcription factor 1
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of HES1 mRNA alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HES1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]
CTD
PMID:29094188
NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
G
HGF
hepatocyte growth factor
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HGF mRNA
CTD
PMID:23519560
NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438
G
HHIP
hedgehog interacting protein
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HHIP mRNA
CTD
PMID:23519560
NCBI chr 4:144,646,156...144,745,271
Ensembl chr 4:144,646,156...144,745,271
G
HIF1A
hypoxia inducible factor 1 subunit alpha
increases expression
ISO
Methylcholanthrene results in increased expression of HIF1A mRNA
CTD
PMID:23273579
NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
G
HIPK2
homeodomain interacting protein kinase 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of HIPK2 mRNA
CTD
PMID:20713471
NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998
G
HLA-DMB
major histocompatibility complex, class II, DM beta
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of H2-DMB1 mRNA
CTD
PMID:23519560
NCBI chr 6:32,934,636...32,941,028
Ensembl chr 6:32,934,629...32,941,028
G
HMGA1
high mobility group AT-hook 1
increases expression
ISO
Methylcholanthrene results in increased expression of HMGA1 mRNA
CTD
PMID:20713471
NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231
G
HMGA2
high mobility group AT-hook 2
increases expression
ISO
Methylcholanthrene results in increased expression of HMGA2 mRNA
CTD
PMID:20713471
NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291
G
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
decreases expression
ISO
Methylcholanthrene results in decreased expression of HMGCR mRNA
CTD
PMID:35487396
NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
G
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of HMGCS1 mRNA
CTD
PMID:20713471 PMID:35487396
NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512
G
HMMR
hyaluronan mediated motility receptor
increases expression
ISO
Methylcholanthrene results in increased expression of HMMR mRNA
CTD
PMID:20713471
NCBI chr 5:163,460,632...163,491,941
Ensembl chr 5:163,460,203...163,491,941
G
HMOX1
heme oxygenase 1
multiple interactions increases expression
ISO EXP
[Methylcholanthrene co-treated with Copper] results in increased expression of HMOX1 mRNA; [Methylcholanthrene co-treated with Lead] results in increased expression of HMOX1 mRNA; [Methylcholanthrene co-treated with Mercury] results in increased expression of HMOX1 mRNA Methylcholanthrene results in increased expression of HMOX1 mRNA
CTD
PMID:15297030 PMID:19889059 PMID:22100608
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
G
HNRNPA1
heterogeneous nuclear ribonucleoprotein A1
multiple interactions
ISO
[Butylated Hydroxytoluene co-treated with Methylcholanthrene] affects the localization of HNRNPA1 protein; [Butylated Hydroxytoluene co-treated with Methylcholanthrene] results in increased expression of HNRNPA1 protein
CTD
PMID:15390079
NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
G
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
multiple interactions
ISO
[Methylcholanthrene co-treated with Butylated Hydroxytoluene] affects the expression of HNRNPA2B1 protein
CTD
PMID:17477362
NCBI chr 7:26,189,927...26,200,746
Ensembl chr 7:26,171,151...26,201,529
G
HOXC10
homeobox C10
increases expression
EXP
Methylcholanthrene results in increased expression of HOXC10 mRNA
CTD
PMID:20348232
NCBI chr12:53,985,146...53,990,279
Ensembl chr12:53,985,065...53,990,279
G
HOXC11
homeobox C11
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to HOXC11 promoter]
CTD
PMID:20348232
NCBI chr12:53,973,126...53,977,643
Ensembl chr12:53,973,126...53,977,643
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HPCAL4
hippocalcin like 4
increases expression
ISO
Methylcholanthrene results in increased expression of HPCAL4 mRNA
CTD
PMID:25926378
NCBI chr 1:39,678,648...39,691,433
Ensembl chr 1:39,678,648...39,691,485
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HPGD
15-hydroxyprostaglandin dehydrogenase
increases expression
ISO
Methylcholanthrene results in increased expression of HPGD mRNA
CTD
PMID:25926378
NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154
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HSBP1
heat shock factor binding protein 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to HSBP1 promoter]
CTD
PMID:20348232
NCBI chr16:83,807,978...83,819,737
Ensembl chr16:83,719,311...83,819,737
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HSCB
HscB mitochondrial iron-sulfur cluster cochaperone
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of HSCB mRNA
CTD
PMID:25926378
NCBI chr22:28,742,032...28,757,510
Ensembl chr22:28,742,039...28,757,515
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HSP90AA1
heat shock protein 90 alpha family class A member 1
increases expression
ISO
Methylcholanthrene results in increased expression of HSP90AA1 mRNA
CTD
PMID:23273579
NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
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HSPA1A
heat shock protein family A (Hsp70) member 1A
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA1A mRNA
CTD
PMID:23519560
NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
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HSPA8
heat shock protein family A (Hsp70) member 8
multiple interactions increases expression
ISO
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HSPA8 mRNA]
CTD
PMID:29094188
NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
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ICAM1
intercellular adhesion molecule 1
increases expression increases acetylation multiple interactions
ISO
Methylcholanthrene results in increased expression of ICAM1 mRNA Methylcholanthrene results in increased acetylation of ICAM1 promoter alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of ICAM1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of ICAM1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]
CTD
PMID:29094188
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
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ID2
inhibitor of DNA binding 2
increases expression
ISO EXP
Methylcholanthrene results in increased expression of ID2 mRNA
CTD
PMID:20713471 PMID:23397585
NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
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ID3
inhibitor of DNA binding 3
increases expression
EXP
Methylcholanthrene results in increased expression of ID3 mRNA
CTD
PMID:23397585
NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501
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IDH2
isocitrate dehydrogenase (NADP(+)) 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to IDH2 promoter]
CTD
PMID:20348232
NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477
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IDI1
isopentenyl-diphosphate delta isomerase 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of IDI1 mRNA
CTD
PMID:20713471
NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119
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IER3
immediate early response 3
increases expression multiple interactions
ISO EXP
Methylcholanthrene results in increased expression of IER3 mRNA Methylcholanthrene promotes the reaction [AHR protein binds to IER3 promoter]
CTD
PMID:20348232 PMID:20713471 PMID:22579512
NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548
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IFI27
interferon alpha inducible protein 27
decreases expression
ISO
Methylcholanthrene results in decreased expression of IFI27 mRNA
CTD
PMID:20713471
NCBI chr14:94,105,894...94,116,690
Ensembl chr14:94,104,836...94,116,695
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IFI44
interferon induced protein 44
decreases expression
ISO
Methylcholanthrene results in decreased expression of IFI44 mRNA
CTD
PMID:20713471
NCBI chr 1:78,649,789...78,664,078
Ensembl chr 1:78,649,796...78,664,078
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IFIT1
interferon induced protein with tetratricopeptide repeats 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of IFIT1 mRNA
CTD
PMID:20713471
NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487
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IFIT2
interferon induced protein with tetratricopeptide repeats 2
increases expression
ISO
Methylcholanthrene results in increased expression of IFIT2 mRNA
CTD
PMID:29554273
NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271
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IFIT3
interferon induced protein with tetratricopeptide repeats 3
decreases expression
ISO
Methylcholanthrene results in decreased expression of IFIT3 mRNA
CTD
PMID:20713471
NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,307...89,377,473
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IFNB1
interferon beta 1
increases expression
ISO
Methylcholanthrene results in increased expression of IFNB1 mRNA
CTD
PMID:29554273
NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942
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IGF2
insulin like growth factor 2
multiple interactions increases expression increases methylation increases acetylation
ISO
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of IGF2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IGF2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of IGF2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]
CTD
PMID:29094188
NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391
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IGFBP6
insulin like growth factor binding protein 6
increases expression
ISO
Methylcholanthrene results in increased expression of IGFBP6 mRNA
CTD
PMID:20713471
NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345
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IGFBPL1
insulin like growth factor binding protein like 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to IGFBPL1 promoter]
CTD
PMID:20348232
NCBI chr 9:38,406,528...38,424,454
Ensembl chr 9:38,406,528...38,424,454
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IGHM
immunoglobulin heavy constant mu
increases expression
ISO
Methylcholanthrene results in increased expression of IGHM mRNA
CTD
PMID:25926378
NCBI chr14:105,851,966...105,856,217
Ensembl chr14:105,851,705...105,856,218
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IL12A
interleukin 12A
increases expression
EXP
Methylcholanthrene results in increased expression of IL12A mRNA
CTD
PMID:14993811
NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
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IL12RB1
interleukin 12 receptor subunit beta 1
increases expression
ISO
Methylcholanthrene results in increased expression of IL12RB1 mRNA
CTD
PMID:20713471
NCBI chr19:18,058,995...18,098,816
Ensembl chr19:18,058,995...18,098,944
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IL18
interleukin 18
increases expression
EXP
Methylcholanthrene results in increased expression of IL18 mRNA
CTD
PMID:14993811
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
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IL18R1
interleukin 18 receptor 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of IL18R1 mRNA
CTD
PMID:25926378
NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777
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IL18RAP
interleukin 18 receptor accessory protein
increases expression
ISO
Methylcholanthrene results in increased expression of IL18RAP mRNA
CTD
PMID:20713471
NCBI chr 2:102,418,621...102,452,565
Ensembl chr 2:102,418,689...102,452,565
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IL1A
interleukin 1 alpha
increases expression
EXP
Methylcholanthrene results in increased expression of IL1A mRNA
CTD
PMID:14993811
NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
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IL1B
interleukin 1 beta
increases expression multiple interactions
EXP ISO
Methylcholanthrene results in increased expression of IL1B mRNA [Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of IL1B mRNA; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IL1B mRNA]
CTD
PMID:14993811 PMID:35487396
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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IL1RL1
interleukin 1 receptor like 1
increases expression
ISO
Methylcholanthrene results in increased expression of IL1RL1 mRNA
CTD
PMID:20713471
NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037
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IL6
interleukin 6
increases expression multiple interactions
EXP ISO
Methylcholanthrene results in increased expression of IL6 mRNA [Methylcholanthrene co-treated with TNF protein] results in increased expression of IL6 mRNA
CTD
PMID:14993811 PMID:23396138 PMID:29554273
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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IL6ST
interleukin 6 cytokine family signal transducer
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of IL6ST mRNA
CTD
PMID:25926378
NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022
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IL7R
interleukin 7 receptor
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of IL7R mRNA [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of IL7R mRNA
CTD
PMID:25926378
NCBI chr 5:35,856,891...35,879,603
Ensembl chr 5:35,852,695...35,879,603
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IMMP2L
inner mitochondrial membrane peptidase subunit 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of IMMP2L mRNA
CTD
PMID:20713471
NCBI chr 7:110,662,644...111,562,492
Ensembl chr 7:110,662,644...111,562,517
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INHBC
inhibin subunit beta C
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to INHBC promoter]
CTD
PMID:20348232
NCBI chr12:57,434,784...57,452,062
Ensembl chr12:57,434,784...57,452,062
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INS
insulin
multiple interactions
EXP
Methylcholanthrene promotes the reaction [Glucose results in increased secretion of INS protein alternative form]
CTD
PMID:31776611
NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
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IQGAP3
IQ motif containing GTPase activating protein 3
increases expression
ISO
Methylcholanthrene results in increased expression of IQGAP3 mRNA
CTD
PMID:20713471
NCBI chr 1:156,525,405...156,572,565
Ensembl chr 1:156,525,405...156,572,604
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IRF2BPL
interferon regulatory factor 2 binding protein like
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to IRF2BPL promoter]
CTD
PMID:20348232
NCBI chr14:77,024,543...77,028,708
Ensembl chr14:77,024,543...77,028,708
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IRS1
insulin receptor substrate 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of IRS1 mRNA
CTD
PMID:29554273
NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820
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ISOC2
isochorismatase domain containing 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ISOC2 promoter]
CTD
PMID:20348232
NCBI chr19:55,452,985...55,461,642
Ensembl chr19:55,452,985...55,462,343
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ITGA10
integrin subunit alpha 10
increases expression
ISO
Methylcholanthrene results in increased expression of ITGA10 mRNA
CTD
PMID:20713471
NCBI chr 1:145,891,208...145,910,050
Ensembl chr 1:145,891,208...145,910,111
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ITGA7
integrin subunit alpha 7
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGA7 mRNA
CTD
PMID:23519560
NCBI chr12:55,684,568...55,716,400
Ensembl chr12:55,684,568...55,716,404
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ITGB5
integrin subunit beta 5
decreases expression
EXP
Methylcholanthrene results in decreased expression of ITGB5 mRNA
CTD
PMID:23397585
NCBI chr 3:124,761,948...124,901,418
Ensembl chr 3:124,761,948...124,901,418
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ITGB8
integrin subunit beta 8
decreases expression multiple interactions
ISO
Methylcholanthrene results in decreased expression of ITGB8 mRNA alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ITGB8 mRNA]
CTD
PMID:29094188
NCBI chr 7:20,329,766...20,415,754
Ensembl chr 7:20,330,702...20,415,754
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ITGBL1
integrin subunit beta like 1
increases expression
ISO
Methylcholanthrene results in increased expression of ITGBL1 mRNA
CTD
PMID:20713471
NCBI chr13:101,452,675...101,720,856
Ensembl chr13:101,452,593...101,720,856
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ITPR1
inositol 1,4,5-trisphosphate receptor type 1
multiple interactions increases expression
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ITPR1 promoter] Methylcholanthrene results in increased expression of ITPR1 mRNA
CTD
PMID:20348232
NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
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JAG1
jagged canonical Notch ligand 1
decreases expression increases expression increases methylation increases acetylation multiple interactions
ISO
Methylcholanthrene results in decreased expression of JAG1 mRNA Methylcholanthrene results in increased expression of JAG1 mRNA Methylcholanthrene results in increased methylation of JAG1 promoter Methylcholanthrene results in increased acetylation of JAG1 promoter alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of JAG1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of JAG1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of JAG1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]
CTD
PMID:20713471 PMID:29094188
NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999
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JAK2
Janus kinase 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of JAK2 mRNA
CTD
PMID:22978700
NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
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JPH1
junctophilin 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to JPH1 promoter]
CTD
PMID:20348232
NCBI chr 8:74,234,700...74,321,540
Ensembl chr 8:74,234,700...74,321,540
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JUN
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Methylcholanthrene results in increased expression of JUN mRNA
CTD
PMID:20713471
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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KATNAL2
katanin catalytic subunit A1 like 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to KATNAL2 promoter]
CTD
PMID:20348232
NCBI chr18:46,917,594...47,102,243
Ensembl chr18:46,917,492...47,103,478
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KCNK2
potassium two pore domain channel subfamily K member 2
increases expression
ISO
Methylcholanthrene results in increased expression of KCNK2 mRNA
CTD
PMID:20713471
NCBI chr 1:215,005,542...215,237,090
Ensembl chr 1:215,005,775...215,237,090
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KCNN4
potassium calcium-activated channel subfamily N member 4
increases expression
ISO
Methylcholanthrene results in increased expression of KCNN4 mRNA
CTD
PMID:20713471
NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976
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KCTD1
potassium channel tetramerization domain containing 1
increases expression
ISO
Methylcholanthrene results in increased expression of KCTD1 mRNA
CTD
PMID:25926378
NCBI chr18:26,454,910...26,657,473
Ensembl chr18:26,454,910...26,657,401
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KCTD16
potassium channel tetramerization domain containing 16
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to KCTD16 promoter]
CTD
PMID:20348232
NCBI chr 5:144,170,873...144,485,686
Ensembl chr 5:144,170,873...144,485,686
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KCTD3
potassium channel tetramerization domain containing 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to KCTD3 promoter]
CTD
PMID:20348232
NCBI chr 1:215,567,304...215,621,807
Ensembl chr 1:215,567,304...215,621,807
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KCTD5
potassium channel tetramerization domain containing 5
decreases expression
ISO
Methylcholanthrene results in decreased expression of KCTD5 mRNA
CTD
PMID:20713471
NCBI chr16:2,682,523...2,709,030
Ensembl chr16:2,682,523...2,709,030
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KDR
kinase insert domain receptor
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of KDR mRNA
CTD
PMID:25926378
NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
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KEAP1
kelch like ECH associated protein 1
increases expression
ISO
Methylcholanthrene results in increased expression of KEAP1 mRNA
CTD
PMID:23712962
NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
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KIF11
kinesin family member 11
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of KIF11 mRNA Methylcholanthrene inhibits the reaction [8-prenylnaringenin results in increased expression of KIF11 mRNA]
CTD
PMID:20713471 PMID:26372666
NCBI chr10:92,593,130...92,655,395
Ensembl chr10:92,574,105...92,655,395
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KIF18A
kinesin family member 18A
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of KIF18A mRNA Methylcholanthrene inhibits the reaction [8-prenylnaringenin results in increased expression of KIF18A mRNA]
CTD
PMID:20713471 PMID:26372666
NCBI chr11:28,020,619...28,108,156
Ensembl chr11:28,020,619...28,108,156
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KIF20A
kinesin family member 20A
increases expression
ISO
Methylcholanthrene results in increased expression of KIF20A mRNA
CTD
PMID:20713471
NCBI chr 5:138,179,112...138,187,723
Ensembl chr 5:138,178,719...138,187,723
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KIF22
kinesin family member 22
increases expression
ISO
Methylcholanthrene results in increased expression of KIF22 mRNA
CTD
PMID:20713471
NCBI chr16:29,790,751...29,805,385
Ensembl chr16:29,790,727...29,805,385
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KIF23
kinesin family member 23
increases expression
ISO
Methylcholanthrene results in increased expression of KIF23 mRNA
CTD
PMID:20713471
NCBI chr15:69,414,349...69,448,427
Ensembl chr15:69,414,246...69,448,427
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KIF2C
kinesin family member 2C
increases expression
ISO
Methylcholanthrene results in increased expression of KIF2C mRNA
CTD
PMID:20713471 PMID:26372666
NCBI chr 1:44,739,837...44,767,767
Ensembl chr 1:44,739,818...44,767,767
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KIR2DL4
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to KIR2DL4 promoter]
CTD
PMID:20348232
NCBI chr19:54,803,610...54,814,517
Ensembl chr19:54,803,610...54,814,517
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KIT
KIT proto-oncogene, receptor tyrosine kinase
affects expression
ISO
Methylcholanthrene affects the expression of KIT mRNA
CTD
PMID:35487396
NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783
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KITLG
KIT ligand
increases expression
ISO
Methylcholanthrene results in increased expression of KITL mRNA
CTD
PMID:20713471
NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851
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KLF2
KLF transcription factor 2
increases expression
ISO
Methylcholanthrene results in increased expression of KLF2 mRNA
CTD
PMID:20713471
NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685
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KLF5
KLF transcription factor 5
increases expression
ISO
Methylcholanthrene results in increased expression of KLF5 mRNA
CTD
PMID:20713471
NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541
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KLF9
KLF transcription factor 9
multiple interactions decreases expression
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to KLF9 promoter] Methylcholanthrene results in decreased expression of KLF9 mRNA
CTD
PMID:20348232 PMID:23397585
NCBI chr 9:70,384,604...70,414,657
Ensembl chr 9:70,384,604...70,414,657
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KMT2E
lysine methyltransferase 2E (inactive)
increases expression
ISO
Methylcholanthrene results in increased expression of KMT2E mRNA
CTD
PMID:25926378
NCBI chr 7:105,014,205...105,115,019
Ensembl chr 7:104,940,943...105,115,019
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KNG1
kininogen 1
multiple interactions decreases expression
ISO
AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 protein] Methylcholanthrene results in decreased expression of KNG1 mRNA; Methylcholanthrene results in decreased expression of KNG1 protein
CTD
PMID:11549291
NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
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KNSTRN
kinetochore localized astrin (SPAG5) binding protein
increases expression
ISO
Methylcholanthrene results in increased expression of KNSTRN mRNA
CTD
PMID:20713471
NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288
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KNTC1
kinetochore associated 1
increases expression
ISO
Methylcholanthrene results in increased expression of KNTC1 mRNA
CTD
PMID:20713471
NCBI chr12:122,527,249...122,626,396
Ensembl chr12:122,527,246...122,626,396
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KPNA2
karyopherin subunit alpha 2
increases expression
ISO
Methylcholanthrene results in increased expression of KPNA2 mRNA
CTD
PMID:20713471
NCBI chr17:68,035,735...68,046,854
Ensembl chr17:68,035,636...68,047,364
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KRAS
KRAS proto-oncogene, GTPase
multiple interactions increases mutagenesis
ISO
Methylcholanthrene promotes the reaction [GATA6 protein binds to KRAS exon]; Methylcholanthrene promotes the reaction [NFYA protein binds to KRAS exon] Methylcholanthrene results in increased mutagenesis of KRAS gene
CTD
PMID:11195466 PMID:16271038 PMID:20101149
NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
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KRT6A
keratin 6A
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of KRT6A mRNA; [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of KRT6A mRNA
CTD
PMID:25926378
NCBI chr12:52,487,176...52,493,257
Ensembl chr12:52,487,176...52,493,257
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KRT75
keratin 75
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to KRT75 promoter]
CTD
PMID:20348232
NCBI chr12:52,424,070...52,434,371
Ensembl chr12:52,424,070...52,434,371
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LAMA4
laminin subunit alpha 4
decreases expression
ISO
Methylcholanthrene results in decreased expression of LAMA4 mRNA
CTD
PMID:29554273
NCBI chr 6:112,107,931...112,254,985
Ensembl chr 6:112,107,931...112,254,939
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LAMA5
laminin subunit alpha 5
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMA5 mRNA
CTD
PMID:23519560
NCBI chr20:62,309,065...62,367,312
Ensembl chr20:62,307,955...62,367,312
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LAMC2
laminin subunit gamma 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMC2 mRNA
CTD
PMID:23519560
NCBI chr 1:183,186,264...183,258,968
Ensembl chr 1:183,186,238...183,245,127
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LCAT
lecithin-cholesterol acyltransferase
decreases expression
ISO
Methylcholanthrene results in decreased expression of LCAT mRNA
CTD
PMID:11328961
NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
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LDLR
low density lipoprotein receptor
decreases expression
ISO
Methylcholanthrene results in decreased expression of LDLR mRNA
CTD
PMID:35487396
NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
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LEF1
lymphoid enhancer binding factor 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LEF1 mRNA
CTD
PMID:23519560
NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956
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LGALS1
galectin 1
increases expression
EXP
Methylcholanthrene results in increased expression of LGALS1 mRNA
CTD
PMID:22579512
NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
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LGALS2
galectin 2
increases expression
ISO
Methylcholanthrene results in increased expression of LGALS2 mRNA
CTD
PMID:20713471
NCBI chr22:37,570,248...37,580,087
Ensembl chr22:37,570,248...37,582,616
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LGALS3
galectin 3
increases expression
ISO
Methylcholanthrene results in increased expression of LGALS3 mRNA
CTD
PMID:20713471
NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423
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LGALS8
galectin 8
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to LGALS8 promoter]
CTD
PMID:20348232
NCBI chr 1:236,518,214...236,552,981
Ensembl chr 1:236,518,000...236,552,981
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LGI1
leucine rich glioma inactivated 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to LGI1 promoter]
CTD
PMID:20348232
NCBI chr10:93,757,936...93,798,159
Ensembl chr10:93,757,840...93,806,272
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LIF
LIF interleukin 6 family cytokine
increases expression multiple interactions
ISO EXP
Methylcholanthrene results in increased expression of LIF mRNA Methylcholanthrene promotes the reaction [AHR protein binds to LIF promoter]
CTD
PMID:20348232 PMID:20713471
NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
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LIMA1
LIM domain and actin binding 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to LIMA1 promoter]
CTD
PMID:20348232
NCBI chr12:50,175,788...50,283,520
Ensembl chr12:50,175,788...50,283,520
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LINC00173
long intergenic non-protein coding RNA 173
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to LINC00173 promoter]
CTD
PMID:20348232
NCBI chr12:116,533,422...116,536,513
Ensembl chr12:116,533,422...116,536,518
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LMNB1
lamin B1
increases expression
ISO
Methylcholanthrene results in increased expression of LMNB1 mRNA
CTD
PMID:20713471
NCBI chr 5:126,776,623...126,837,020
Ensembl chr 5:126,776,623...126,837,020
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LMTK2
lemur tyrosine kinase 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of LMTK2 mRNA
CTD
PMID:25926378
NCBI chr 7:98,106,862...98,209,638
Ensembl chr 7:98,106,862...98,209,638
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LOX
lysyl oxidase
decreases expression
ISO
Methylcholanthrene results in decreased expression of LOX mRNA
CTD
PMID:20713471
NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413
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LRP11
LDL receptor related protein 11
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to LRP11 promoter]
CTD
PMID:20348232
NCBI chr 6:149,818,757...149,864,359
Ensembl chr 6:149,818,757...149,864,359
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LRR1
leucine rich repeat protein 1
increases expression
ISO
Methylcholanthrene results in increased expression of LRR1 mRNA
CTD
PMID:20713471
NCBI chr14:49,598,940...49,614,672
Ensembl chr14:49,598,761...49,614,672
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LRRC8D
leucine rich repeat containing 8 VRAC subunit D
increases expression
ISO
Methylcholanthrene results in increased expression of LRRC8D mRNA
CTD
PMID:20713471
NCBI chr 1:89,821,032...89,936,611
Ensembl chr 1:89,821,014...89,936,611
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LSM4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
increases expression
ISO
Methylcholanthrene results in increased expression of LSM4 mRNA
CTD
PMID:20713471
NCBI chr19:18,306,236...18,323,076
Ensembl chr19:18,306,236...18,323,112
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LSM5
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to LSM5 promoter]
CTD
PMID:20348232
NCBI chr 7:32,485,338...32,495,283
Ensembl chr 7:32,485,338...32,495,283
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LSM6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
increases expression
ISO
Methylcholanthrene results in increased expression of LSM6 mRNA
CTD
PMID:20713471
NCBI chr 4:146,175,718...146,191,535
Ensembl chr 4:146,175,703...146,200,000
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LTBP1
latent transforming growth factor beta binding protein 1
increases expression
ISO
Methylcholanthrene results in increased expression of LTBP1 mRNA
CTD
PMID:20713471
NCBI chr 2:32,946,953...33,399,509
Ensembl chr 2:32,946,953...33,399,509
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LUM
lumican
decreases expression
ISO
Methylcholanthrene results in decreased expression of LUM mRNA
CTD
PMID:20713471
NCBI chr12:91,102,629...91,111,494
Ensembl chr12:91,102,629...91,111,494
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LY6E
lymphocyte antigen 6 family member E
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to LY6E promoter]
CTD
PMID:20348232
NCBI chr 8:143,018,529...143,022,409
Ensembl chr 8:143,017,982...143,023,832
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LY6S
lymphocyte antigen 6 family member S
increases expression
ISO
Methylcholanthrene results in increased expression of LY6A mRNA
CTD
PMID:20713471
NCBI chr 8:143,040,839...143,076,471
Ensembl chr 8:143,041,844...143,045,678
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MAD1L1
mitotic arrest deficient 1 like 1
increases expression
ISO
Methylcholanthrene results in increased expression of MAD1L1 mRNA
CTD
PMID:20713471
NCBI chr 7:1,815,795...2,232,945
Ensembl chr 7:1,815,793...2,233,243
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MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAGI1 mRNA
CTD
PMID:23519560
NCBI chr 3:65,353,526...66,038,918
Ensembl chr 3:65,353,525...66,038,918
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MALAT1
metastasis associated lung adenocarcinoma transcript 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of MALAT1 mRNA
CTD
PMID:20713471
NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,640...65,508,073
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MAP2K1
mitogen-activated protein kinase kinase 1
increases expression
ISO
Methylcholanthrene results in increased expression of MAP2K1 mRNA
CTD
PMID:25926378
NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
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MAP2K3
mitogen-activated protein kinase kinase 3
increases expression
ISO
Methylcholanthrene results in increased expression of MAP2K3 mRNA
CTD
PMID:20713471
NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,232
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MAPK1
mitogen-activated protein kinase 1
increases expression
ISO
Methylcholanthrene results in increased expression of MAPK1 mRNA
CTD
PMID:23712962
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK8
mitogen-activated protein kinase 8
multiple interactions
EXP
Methylcholanthrene results in increased phosphorylation of and results in increased activity of MAPK8 protein
CTD
PMID:16619036
NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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MAPKAP1
MAPK associated protein 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MAPKAP1 promoter]
CTD
PMID:20348232
NCBI chr 9:125,437,394...125,707,208
Ensembl chr 9:125,437,393...125,707,234
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MARCKS
myristoylated alanine rich protein kinase C substrate
decreases expression
ISO
Methylcholanthrene results in decreased expression of MARCKS mRNA
CTD
PMID:20713471
NCBI chr 6:113,857,345...113,863,475
Ensembl chr 6:113,857,345...113,863,475
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MASTL
microtubule associated serine/threonine kinase like
increases expression
ISO
Methylcholanthrene results in increased expression of MASTL mRNA
CTD
PMID:20713471
NCBI chr10:27,154,479...27,187,953
Ensembl chr10:27,154,824...27,187,953
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MAT1A
methionine adenosyltransferase 1A
decreases expression
EXP
Methylcholanthrene results in decreased expression of MAT1A mRNA
CTD
PMID:22100608
NCBI chr10:80,271,820...80,289,658
Ensembl chr10:80,271,820...80,289,658
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MATN2
matrilin 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of MATN2 mRNA
CTD
PMID:20713471
NCBI chr 8:97,869,064...98,036,724
Ensembl chr 8:97,868,840...98,036,724
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MBNL1
muscleblind like splicing regulator 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MBNL1 promoter]
CTD
PMID:20348232
NCBI chr 3:152,243,632...152,465,780
Ensembl chr 3:152,243,828...152,465,780
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MCM10
minichromosome maintenance 10 replication initiation factor
increases expression
ISO
Methylcholanthrene results in increased expression of MCM10 mRNA
CTD
PMID:20713471
NCBI chr10:13,161,558...13,211,110
Ensembl chr10:13,161,558...13,211,110
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MCM3
minichromosome maintenance complex component 3
increases expression
ISO
Methylcholanthrene results in increased expression of MCM3 mRNA
CTD
PMID:20713471
NCBI chr 6:52,264,015...52,284,742
Ensembl chr 6:52,264,014...52,284,881
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MCM4
minichromosome maintenance complex component 4
increases expression
ISO
Methylcholanthrene results in increased expression of MCM4 mRNA
CTD
PMID:20713471
NCBI chr 8:47,960,941...47,978,160
Ensembl chr 8:47,960,185...47,978,160
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MCM5
minichromosome maintenance complex component 5
increases expression
ISO
Methylcholanthrene results in increased expression of MCM5 mRNA
CTD
PMID:20713471
NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431
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MCM6
minichromosome maintenance complex component 6
increases expression
ISO
Methylcholanthrene results in increased expression of MCM6 mRNA
CTD
PMID:20713471
NCBI chr 2:135,839,626...135,876,443
Ensembl chr 2:135,839,626...135,876,443
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MED13L
mediator complex subunit 13L
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MED13L promoter]
CTD
PMID:20348232
NCBI chr12:115,958,576...116,277,693
Ensembl chr12:115,957,905...116,277,693
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MELK
maternal embryonic leucine zipper kinase
increases expression
ISO
Methylcholanthrene results in increased expression of MELK mRNA
CTD
PMID:20713471
NCBI chr 9:36,572,895...36,677,682
Ensembl chr 9:36,572,862...36,677,683
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MESP1
mesoderm posterior bHLH transcription factor 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MESP1 promoter]
CTD
PMID:20348232
NCBI chr15:89,732,446...89,751,249
Ensembl chr15:89,749,875...89,751,249
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MFAP3L
microfibril associated protein 3 like
increases expression
ISO
Methylcholanthrene results in increased expression of MFAP3L mRNA
CTD
PMID:20713471
NCBI chr 4:169,986,602...170,027,277
Ensembl chr 4:169,986,597...170,033,031
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MGST2
microsomal glutathione S-transferase 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MGST2 promoter]
CTD
PMID:20348232
NCBI chr 4:139,665,819...139,754,618
Ensembl chr 4:139,665,768...139,740,745
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MID1
midline 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of MID1 mRNA
CTD
PMID:20713471
NCBI chr X:10,445,310...10,833,683
Ensembl chr X:10,445,310...10,833,654
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MIDEAS
mitotic deacetylase associated SANT domain protein
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MIDEAS promoter]
CTD
PMID:20348232
NCBI chr14:73,715,122...73,790,285
Ensembl chr14:73,715,122...73,790,285
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MIR101-2
microRNA 101-2
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR101B mRNA
CTD
PMID:25926378
NCBI chr 9:4,850,297...4,850,375
Ensembl chr 9:4,850,297...4,850,375
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MIR122
microRNA 122
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR122 mRNA
CTD
PMID:25926378
NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158
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MIR130A
microRNA 130a
affects expression
ISO
Methylcholanthrene affects the expression of MIR130A mRNA
CTD
PMID:25926378
NCBI chr11:57,641,198...57,641,286
Ensembl chr11:57,641,198...57,641,286
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MIR130B
microRNA 130b
decreases expression
ISO
Methylcholanthrene results in decreased expression of MIR130B mRNA
CTD
PMID:25926378
NCBI chr22:21,653,304...21,653,385
Ensembl chr22:21,653,304...21,653,385
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MIR144
microRNA 144
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR144 mRNA
CTD
PMID:25926378
NCBI chr17:28,861,533...28,861,618
Ensembl chr17:28,861,533...28,861,618
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MIR145
microRNA 145
decreases expression
ISO
Methylcholanthrene results in decreased expression of MIR145A mRNA
CTD
PMID:25926378
NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733
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MIR15A
microRNA 15a
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of MIR15A mRNA [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR15A mRNA
CTD
PMID:25926378
NCBI chr13:50,049,119...50,049,201
Ensembl chr13:50,049,119...50,049,201
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MIR18B
microRNA 18b
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR18B mRNA
CTD
PMID:25926378
NCBI chr X:134,170,041...134,170,111
Ensembl chr X:134,170,041...134,170,111
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MIR191
microRNA 191
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR191 mRNA
CTD
PMID:25926378
NCBI chr 3:49,020,618...49,020,709
Ensembl chr 3:49,020,618...49,020,709
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MIR19A
microRNA 19a
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR19A mRNA
CTD
PMID:25926378
NCBI chr13:91,350,891...91,350,972
Ensembl chr13:91,350,891...91,350,972
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MIR203B
microRNA 203b
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR203 mRNA
CTD
PMID:25926378
NCBI chr14:104,117,418...104,117,503
Ensembl chr14:104,117,418...104,117,503
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MIR206
microRNA 206
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR206 mRNA
CTD
PMID:25926378
NCBI chr 6:52,144,349...52,144,434
Ensembl chr 6:52,144,349...52,144,434
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MIR210
microRNA 210
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR210 mRNA
CTD
PMID:25926378
NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198
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MIR211
microRNA 211
decreases expression
ISO
Methylcholanthrene results in decreased expression of MIR211 mRNA
CTD
PMID:25926378
NCBI chr15:31,065,032...31,065,141
Ensembl chr15:31,065,032...31,065,141
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MIR29C
microRNA 29c
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR29C mRNA
CTD
PMID:25926378
NCBI chr 1:207,801,852...207,801,939
Ensembl chr 1:207,801,852...207,801,939
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MIR32
microRNA 32
multiple interactions decreases expression
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR32 mRNA Methylcholanthrene results in decreased expression of MIR32 mRNA
CTD
PMID:25926378
NCBI chr 9:109,046,229...109,046,298
Ensembl chr 9:109,046,229...109,046,298
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MIR340
microRNA 340
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR340 mRNA
CTD
PMID:25926378
NCBI chr 5:180,015,303...180,015,397
Ensembl chr 5:180,015,303...180,015,397
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MIR345
microRNA 345
multiple interactions affects expression
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR345 mRNA Methylcholanthrene affects the expression of MIR345 mRNA
CTD
PMID:25926378
NCBI chr14:100,307,859...100,307,956
Ensembl chr14:100,307,859...100,307,956
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MIR362
microRNA 362
increases expression
ISO
Methylcholanthrene results in increased expression of MIR362 mRNA
CTD
PMID:25926378
NCBI chr X:50,008,964...50,009,028
Ensembl chr X:50,008,964...50,009,028
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MIR425
microRNA 425
decreases expression
ISO
Methylcholanthrene results in decreased expression of MIR425 mRNA
CTD
PMID:25926378
NCBI chr 3:49,020,148...49,020,234
Ensembl chr 3:49,020,148...49,020,234
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MIR449A
microRNA 449a
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR449A mRNA
CTD
PMID:25926378
NCBI chr 5:55,170,532...55,170,622
Ensembl chr 5:55,170,532...55,170,622
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MIR497
microRNA 497
increases expression
ISO
Methylcholanthrene results in increased expression of MIR497 mRNA
CTD
PMID:25926378
NCBI chr17:7,017,911...7,018,022
Ensembl chr17:7,017,911...7,018,022
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MIR574
microRNA 574
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR574 mRNA
CTD
PMID:25926378
NCBI chr 4:38,868,032...38,868,127
Ensembl chr 4:38,868,032...38,868,127
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MIR92A2
microRNA 92a-2
decreases expression
ISO
Methylcholanthrene results in decreased expression of MIR92-2 mRNA
CTD
PMID:25926378
NCBI chr X:134,169,538...134,169,612
Ensembl chr X:134,169,538...134,169,612
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MKI67
marker of proliferation Ki-67
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of MKI67 mRNA Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of MKI67 mRNA]; Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of MKI67 protein]
CTD
PMID:20713471 PMID:26372666
NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
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MLLT6
MLLT6, PHD finger containing
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MLLT6 promoter]
CTD
PMID:20348232
NCBI chr17:38,705,273...38,729,795
Ensembl chr17:38,705,273...38,729,795
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MLPH
melanophilin
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MLPH promoter]
CTD
PMID:20348232
NCBI chr 2:237,486,410...237,555,322
Ensembl chr 2:237,485,428...237,555,322
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MMP1
matrix metallopeptidase 1
increases expression
ISO
Methylcholanthrene results in increased expression of MMP1 mRNA
CTD
PMID:29554273
NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
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MMP13
matrix metallopeptidase 13
increases expression decreases expression
ISO
Methylcholanthrene results in increased expression of MMP13 mRNA Methylcholanthrene results in decreased expression of MMP13 mRNA
CTD
PMID:20713471 PMID:29554273
NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
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MMP2
matrix metallopeptidase 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Diethylnitrosamine] results in increased expression of MMP2 mRNA; [Methylcholanthrene co-treated with Diethylnitrosamine] results in increased expression of MMP2 protein
CTD
PMID:12015029
NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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MMP3
matrix metallopeptidase 3
increases expression
ISO
Methylcholanthrene results in increased expression of MMP3 mRNA
CTD
PMID:20713471
NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
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MMP9
matrix metallopeptidase 9
multiple interactions decreases expression
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MMP9 mRNA Methylcholanthrene results in decreased expression of MMP9 mRNA
CTD
PMID:23519560 PMID:29554273
NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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MPI
mannose phosphate isomerase
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MPI promoter]
CTD
PMID:20348232
NCBI chr15:74,890,042...74,902,219
Ensembl chr15:74,890,005...74,902,219
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MPL
MPL proto-oncogene, thrombopoietin receptor
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MPL mRNA
CTD
PMID:25926378
NCBI chr 1:43,337,818...43,354,466
Ensembl chr 1:43,337,818...43,354,466
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MRTFB
myocardin related transcription factor B
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MRTFB promoter]
CTD
PMID:20348232
NCBI chr16:13,994,774...14,266,779
Ensembl chr16:14,071,319...14,266,773
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MS4A7
membrane spanning 4-domains A7
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MS4A7 promoter]
CTD
PMID:20348232
NCBI chr11:60,378,532...60,395,948
Ensembl chr11:60,378,485...60,395,951
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MSH4
mutS homolog 4
decreases expression
ISO
Methylcholanthrene results in decreased expression of MSH4 mRNA
CTD
PMID:35487396
NCBI chr 1:75,796,882...75,913,242
Ensembl chr 1:75,796,882...75,913,242
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MSH5
mutS homolog 5
decreases expression
ISO
Methylcholanthrene results in decreased expression of MSH5 mRNA
CTD
PMID:35487396
NCBI chr 6:31,740,005...31,762,676
Ensembl chr 6:31,739,677...31,762,676
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MSLN
mesothelin
increases expression
ISO
Methylcholanthrene results in increased expression of MSLN mRNA
CTD
PMID:20713471
NCBI chr16:760,734...768,865
Ensembl chr16:760,734...768,865
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MSMB
microseminoprotein beta
multiple interactions affects binding increases expression
EXP ISO
Methylcholanthrene promotes the reaction [AHR protein binds to MSMB promoter] Methylcholanthrene binds to MSMB protein Methylcholanthrene results in increased expression of MSMB mRNA
CTD
PMID:3940634 PMID:20348232
NCBI chr10:46,033,313...46,046,269
Ensembl chr10:46,033,307...46,048,180
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MSMO1
methylsterol monooxygenase 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of MSMO1 mRNA
CTD
PMID:20713471
NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164
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MT2A
metallothionein 2A
multiple interactions increases expression
EXP
AHR protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; Methylcholanthrene promotes the reaction [Dexamethasone results in increased expression of MT2A mRNA]; NR3C1 protein affects the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene promotes the reaction [Dexamethasone results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]
CTD
PMID:23994556
NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
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MTCL3
MTCL family member 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MTCL3 promoter]
CTD
PMID:20348232
NCBI chr 6:127,472,974...127,519,335
Ensembl chr 6:127,472,806...127,519,335
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MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MTHFD2 mRNA
CTD
PMID:25926378
NCBI chr 2:74,198,615...74,217,565
Ensembl chr 2:74,186,172...74,217,565
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MX1
MX dynamin like GTPase 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of MX2 mRNA
CTD
PMID:20713471
NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071
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MYBL1
MYB proto-oncogene like 1
affects expression
ISO
Methylcholanthrene affects the expression of MYBL1 mRNA
CTD
PMID:35487396
NCBI chr 8:66,562,175...66,613,218
Ensembl chr 8:66,562,175...66,614,247
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MYBL2
MYB proto-oncogene like 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of MYBL2 mRNA
CTD
PMID:35487396
NCBI chr20:43,667,114...43,716,482
Ensembl chr20:43,667,019...43,716,495
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MYH7
myosin heavy chain 7
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MYH7 mRNA
CTD
PMID:25926378
NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660
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MYL9
myosin light chain 9
decreases expression multiple interactions
ISO
Methylcholanthrene results in decreased expression of MYL9 mRNA [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MYL9 mRNA
CTD
PMID:20713471 PMID:25926378
NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447
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MYLK
myosin light chain kinase
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MYLK mRNA
CTD
PMID:23519560
NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
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MYO1D
myosin ID
decreases expression
ISO
Methylcholanthrene results in decreased expression of MYO1D mRNA
CTD
PMID:20713471
NCBI chr17:32,492,522...32,877,124
Ensembl chr17:32,492,522...32,877,177
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MYO7A
myosin VIIA
decreases expression
ISO
Methylcholanthrene results in decreased expression of MYO7A mRNA
CTD
PMID:20713471
NCBI chr11:77,128,246...77,215,241
Ensembl chr11:77,128,246...77,215,241
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MYOF
myoferlin
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MYOF promoter]
CTD
PMID:20348232
NCBI chr10:93,306,429...93,482,334
Ensembl chr10:93,306,429...93,482,334
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MYOM2
myomesin 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MYOM2 promoter]
CTD
PMID:20348232
NCBI chr 8:2,045,046...2,145,456
Ensembl chr 8:2,045,046...2,165,552
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NASP
nuclear autoantigenic sperm protein
increases expression
ISO
Methylcholanthrene results in increased expression of NASP mRNA
CTD
PMID:20713471
NCBI chr 1:45,584,041...45,618,893
Ensembl chr 1:45,583,846...45,618,904
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NBPF10
NBPF member 10
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to NBPF10 promoter]
CTD
PMID:20348232
NCBI chr 1:146,064,699...146,144,804
Ensembl chr 1:146,064,711...146,229,000
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NBPF3
NBPF member 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to NBPF3 promoter]
CTD
PMID:20348232
NCBI chr 1:21,436,789...21,484,900
Ensembl chr 1:21,440,128...21,485,005
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NCAM1
neural cell adhesion molecule 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of NCAM1 mRNA
CTD
PMID:20713471
NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436
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NCAPG2
non-SMC condensin II complex subunit G2
increases expression
ISO
Methylcholanthrene results in increased expression of NCAPG2 mRNA
CTD
PMID:20713471
NCBI chr 7:158,631,169...158,704,804
Ensembl chr 7:158,631,169...158,704,804
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NCAPH
non-SMC condensin I complex subunit H
increases expression
ISO
Methylcholanthrene results in increased expression of NCAPH mRNA
CTD
PMID:20713471
NCBI chr 2:96,335,766...96,377,091
Ensembl chr 2:96,335,766...96,377,091
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NCF1
neutrophil cytosolic factor 1
increases expression
EXP
Methylcholanthrene results in increased expression of NCF1 mRNA
CTD
PMID:19559082
NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315
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NCK2
NCK adaptor protein 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of NCK2 mRNA
CTD
PMID:20713471
NCBI chr 2:105,744,453...105,894,272
Ensembl chr 2:105,744,912...105,894,274
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NDC80
NDC80 kinetochore complex component
decreases expression increases expression
EXP ISO
Methylcholanthrene results in decreased expression of NDC80 mRNA Methylcholanthrene results in increased expression of NDC80 mRNA
CTD
PMID:20713471 PMID:22579512
NCBI chr18:2,571,557...2,616,635
Ensembl chr18:2,571,557...2,616,635
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NDRG4
NDRG family member 4
increases expression
ISO
Methylcholanthrene results in increased expression of NDRG4 mRNA
CTD
PMID:20713471
NCBI chr16:58,463,715...58,515,387
Ensembl chr16:58,462,846...58,513,628
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NDST1
N-deacetylase and N-sulfotransferase 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to NDST1 promoter]
CTD
PMID:20348232
NCBI chr 5:150,497,779...150,558,211
Ensembl chr 5:150,485,818...150,558,211
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NEDD9
neural precursor cell expressed, developmentally down-regulated 9
increases expression
EXP
Methylcholanthrene results in increased expression of NEDD9 mRNA
CTD
PMID:16619036
NCBI chr 6:11,183,298...11,382,348
Ensembl chr 6:11,183,298...11,382,348
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NEK2
NIMA related kinase 2
increases expression
ISO
Methylcholanthrene results in increased expression of NEK2 mRNA
CTD
PMID:20713471
NCBI chr 1:211,658,256...211,675,621
Ensembl chr 1:211,658,657...211,675,630
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NELFCD
negative elongation factor complex member C/D
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to NELFCD promoter]
CTD
PMID:20348232
NCBI chr20:58,981,256...58,995,113
Ensembl chr20:58,981,208...58,995,133
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NFATC2
nuclear factor of activated T cells 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of NFATC2 mRNA
CTD
PMID:29554273
NCBI chr20:51,386,963...51,562,839
Ensembl chr20:51,386,957...51,562,831
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NFE2L2
NFE2 like bZIP transcription factor 2
increases expression multiple interactions
ISO EXP
Methylcholanthrene results in increased expression of NFE2L2 mRNA; Methylcholanthrene results in increased expression of NFE2L2 protein Methylcholanthrene promotes the reaction [AHR protein binds to NFE2L2 promoter] NFE2L2 protein affects the reaction [Methylcholanthrene results in increased expression of PSMB5 mRNA]
CTD
PMID:16723119 PMID:20348232 PMID:20713471 PMID:23712962
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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NFKBIA
NFKB inhibitor alpha
increases expression
ISO
Methylcholanthrene results in increased expression of NFKBIA mRNA
CTD
PMID:29554273
NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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NFKBIZ
NFKB inhibitor zeta
increases expression
ISO
Methylcholanthrene results in increased expression of NFKBIZ mRNA
CTD
PMID:20713471
NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022
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NFYA
nuclear transcription factor Y subunit alpha
multiple interactions increases activity
ISO
Methylcholanthrene promotes the reaction [NFYA protein binds to KRAS exon] Methylcholanthrene results in increased activity of NFYA protein
CTD
PMID:16271038
NCBI chr 6:41,072,974...41,102,403
Ensembl chr 6:41,072,974...41,102,403
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NGF
nerve growth factor
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of NGF mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NGF mRNA
CTD
PMID:20713471 PMID:23519560
NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
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NHERF2
NHERF family PDZ scaffold protein 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of NHERF2 mRNA
CTD
PMID:20713471
NCBI chr16:2,026,902...2,039,026
Ensembl chr16:2,025,356...2,039,026
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NIBAN1
niban apoptosis regulator 1
increases expression
ISO
Methylcholanthrene results in increased expression of NIBAN1 mRNA
CTD
PMID:20713471
NCBI chr 1:184,791,032...184,974,508
Ensembl chr 1:184,790,724...184,974,508
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NKD2
NKD inhibitor of WNT signaling pathway 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NKD2 mRNA
CTD
PMID:23519560
NCBI chr 5:1,008,802...1,038,943
Ensembl chr 5:1,008,802...1,038,943
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NMRAL1
NmrA like redox sensor 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to NMRAL1 promoter]
CTD
PMID:20348232
NCBI chr16:4,461,694...4,476,337
Ensembl chr16:4,461,691...4,495,763
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NOP58
NOP58 ribonucleoprotein
increases expression
ISO
Methylcholanthrene results in increased expression of NOL5 mRNA
CTD
PMID:20713471
NCBI chr 2:202,265,763...202,303,661
Ensembl chr 2:202,265,736...202,303,661
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NOTCH2
notch receptor 2
increases expression multiple interactions decreases acetylation increases methylation
ISO
Methylcholanthrene results in increased expression of NOTCH2 mRNA alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of NOTCH2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of NOTCH2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of NOTCH2 promoter]
CTD
PMID:29094188
NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779
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NPPA
natriuretic peptide A
increases expression
ISO
3-methylcholanthrene increases expression of mRNA in rat heart
RGD
PMID:19889059
RGD:401794453
NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
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NPPB
natriuretic peptide B
increases expression
ISO
3-methylcholanthrene increases expression of mRNA in rat heart
RGD
PMID:19889059
RGD:401794453
NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
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NQO1
NAD(P)H quinone dehydrogenase 1
multiple interactions increases expression increases activity
ISO EXP
Arsenic promotes the reaction [Methylcholanthrene results in increased expression of NQO1 mRNA]; Cadmium promotes the reaction [Methylcholanthrene results in increased expression of NQO1 mRNA]; Chromium inhibits the reaction [Methylcholanthrene results in increased activity of NQO1 protein]; Chromium inhibits the reaction [Methylcholanthrene results in increased expression of NQO1 mRNA] Methylcholanthrene results in increased expression of NQO1 mRNA; Methylcholanthrene results in increased expression of NQO1 protein [protocatechuic acid co-treated with Methylcholanthrene] results in increased activity of NQO1 protein; Buthionine Sulfoximine promotes the reaction [Methylcholanthrene results in increased activity of NQO1 protein]; Ethoxyquin promotes the reaction [Methylcholanthrene results in increased activity of NQO1 protein]; Methylcholanthrene promotes the reaction [Buthionine Sulfoximine results in increased activity of NQO1 protein]; Methylcholanthrene promotes the reaction [Ethoxyquin results in increased activity of NQO1 protein]; Methylcholanthrene results in increased expression of and results in increased activity of NQO1 protein
CTD
PMID:4005852 PMID:11323195 PMID:12206817 PMID:15302093 PMID:15337587 PMID:16906435 PMID:17069994 PMID:17253728 PMID:18203689 PMID:20713471 PMID:23273579 PMID:23712962 More...
NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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NQO2
N-ribosyldihydronicotinamide:quinone dehydrogenase 2
increases expression
ISO
Methylcholanthrene results in increased expression of NQO2 mRNA
CTD
PMID:20713471
NCBI chr 6:2,999,894...3,019,755
Ensembl chr 6:2,987,987...3,019,755
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NR0B2
nuclear receptor subfamily 0 group B member 2
increases expression
EXP
Methylcholanthrene results in increased expression of NR0B2 mRNA
CTD
PMID:19118567
NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975
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NR1H3
nuclear receptor subfamily 1 group H member 3
increases expression
ISO
Methylcholanthrene results in increased expression of NR1H3 mRNA
CTD
PMID:23273579
NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
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NR1I3
nuclear receptor subfamily 1 group I member 3
increases expression affects expression
EXP ISO
Methylcholanthrene results in increased expression of NR1I3 mRNA Methylcholanthrene affects the expression of NR1I3 mRNA
CTD
PMID:19118567 PMID:23273579
NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
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NR3C1
nuclear receptor subfamily 3 group C member 1
decreases expression multiple interactions
ISO EXP
Methylcholanthrene results in decreased expression of NR3C1 protein [NR3C1 protein co-treated with Dexamethasone] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [NR3C1 protein co-treated with Dexamethasone] results in decreased susceptibility to Methylcholanthrene; NR3C1 protein affects the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene promotes the reaction [Dexamethasone results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]
CTD
PMID:1638671 PMID:23994556 PMID:24091107
NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
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NR4A1
nuclear receptor subfamily 4 group A member 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of NR4A1 mRNA
CTD
PMID:20713471
NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507
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NREP
neuronal regeneration related protein
decreases expression
ISO
Methylcholanthrene results in decreased expression of NREP mRNA
CTD
PMID:20713471
NCBI chr 5:111,728,802...111,976,932
Ensembl chr 5:111,662,621...111,997,464
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NRN1
neuritin 1
increases expression
ISO
Methylcholanthrene results in increased expression of NRN1 mRNA
CTD
PMID:20713471
NCBI chr 6:5,997,999...6,007,518
Ensembl chr 6:5,997,999...6,007,605
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NRXN2
neurexin 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NRXN2 mRNA
CTD
PMID:23519560
NCBI chr11:64,606,174...64,723,197
Ensembl chr11:64,606,174...64,723,197
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NSDHL
NAD(P) dependent steroid dehydrogenase-like
decreases expression
ISO
Methylcholanthrene results in decreased expression of NSDHL mRNA
CTD
PMID:20713471
NCBI chr X:152,831,063...152,869,729
Ensembl chr X:152,830,967...152,869,729
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NUDT21
nudix hydrolase 21
increases expression
ISO
Methylcholanthrene results in increased expression of NUDT21 mRNA
CTD
PMID:20713471
NCBI chr16:56,429,133...56,451,332
Ensembl chr16:56,429,133...56,452,199
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NUSAP1
nucleolar and spindle associated protein 1
increases expression
ISO
Methylcholanthrene results in increased expression of NUSAP1 mRNA
CTD
PMID:20713471
NCBI chr15:41,332,881...41,381,046
Ensembl chr15:41,320,794...41,381,050
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NXN
nucleoredoxin
decreases expression
ISO
Methylcholanthrene results in decreased expression of NXN mRNA
CTD
PMID:29554273
NCBI chr17:799,310...979,776
Ensembl chr17:799,310...979,776
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NXT2
nuclear transport factor 2 like export factor 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to NXT2 promoter]
CTD
PMID:20348232
NCBI chr X:109,535,824...109,544,698
Ensembl chr X:109,535,781...109,544,698
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OGN
osteoglycin
decreases expression
ISO
Methylcholanthrene results in decreased expression of OGN mRNA
CTD
PMID:20713471
NCBI chr 9:92,383,268...92,404,699
Ensembl chr 9:92,383,268...92,404,696
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OIP5
Opa interacting protein 5
increases expression
ISO
Methylcholanthrene results in increased expression of OIP5 mRNA
CTD
PMID:20713471
NCBI chr15:41,309,273...41,332,591
Ensembl chr15:41,309,273...41,332,591
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OLFM1
olfactomedin 1
increases expression
ISO
Methylcholanthrene results in increased expression of OLFM1 mRNA
CTD
PMID:20713471
NCBI chr 9:135,075,505...135,121,184
Ensembl chr 9:135,075,422...135,121,180
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OR11H4
olfactory receptor family 11 subfamily H member 4
decreases expression
ISO
Methylcholanthrene results in decreased expression of OR11H4 mRNA
CTD
PMID:25926378
NCBI chr14:20,239,286...20,244,349
Ensembl chr14:20,239,286...20,244,349
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OR4D5
olfactory receptor family 4 subfamily D member 5
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of OR4D5 mRNA
CTD
PMID:25926378
NCBI chr11:123,939,617...123,940,573
Ensembl chr11:123,939,617...123,940,573
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OR6S1
olfactory receptor family 6 subfamily S member 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of OR6S1 mRNA
CTD
PMID:25926378
NCBI chr14:20,640,696...20,641,691
Ensembl chr14:20,640,696...20,641,691
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OR8J2
olfactory receptor family 8 subfamily J member 2 (gene/pseudogene)
increases expression
ISO
Methylcholanthrene results in increased expression of OR8J3C mRNA
CTD
PMID:25926378
NCBI chr11:56,208,985...56,215,222
Ensembl chr11:56,208,985...56,215,222
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OSBPL10
oxysterol binding protein like 10
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to OSBPL10 promoter]
CTD
PMID:20348232
NCBI chr 3:31,660,825...32,077,692
Ensembl chr 3:31,657,912...32,077,580
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OSR2
odd-skipped related transciption factor 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of OSR2 mRNA
CTD
PMID:20713471
NCBI chr 8:98,944,442...98,952,100
Ensembl chr 8:98,944,403...98,952,104
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OTUB2
OTU deubiquitinase, ubiquitin aldehyde binding 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to OTUB2 promoter]
CTD
PMID:20348232
NCBI chr14:94,026,340...94,048,930
Ensembl chr14:94,026,340...94,048,930
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OTULINL
OTU deubiquitinase with linear linkage specificity like
increases expression
ISO
Methylcholanthrene results in increased expression of OTULINL mRNA
CTD
PMID:25926378
NCBI chr 5:14,581,792...14,616,180
Ensembl chr 5:14,581,792...14,616,180
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P2RX7
purinergic receptor P2X 7
decreases expression multiple interactions
ISO
Methylcholanthrene results in decreased expression of P2RX7 mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of P2RX7 mRNA
CTD
PMID:20713471 PMID:23519560
NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
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P2RY1
purinergic receptor P2Y1
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of P2RY1 mRNA
CTD
PMID:23519560
NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439
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PAH
phenylalanine hydroxylase
decreases expression
EXP
Methylcholanthrene results in decreased expression of PAH mRNA
CTD
PMID:22579512
NCBI chr12:102,836,889...102,958,441
Ensembl chr12:102,836,889...102,958,410
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PAK6
p21 (RAC1) activated kinase 6
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PAK6 mRNA
CTD
PMID:23519560
NCBI chr15:40,239,063...40,277,487
Ensembl chr15:40,217,428...40,277,487
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PALS2
protein associated with LIN7 2, MAGUK p55 family member
increases expression
ISO
Methylcholanthrene results in increased expression of PALS2 mRNA
CTD
PMID:20713471
NCBI chr 7:24,573,452...24,694,193
Ensembl chr 7:24,573,268...24,694,193
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PARD6B
par-6 family cell polarity regulator beta
decreases expression multiple interactions
ISO
Methylcholanthrene results in decreased expression of PARD6B mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PARD6B mRNA
CTD
PMID:20713471 PMID:23519560
NCBI chr20:50,731,580...50,753,741
Ensembl chr20:50,731,580...50,756,795
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PARP1
poly(ADP-ribose) polymerase 1
multiple interactions
ISO
Methylcholanthrene inhibits the reaction [3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole results in increased cleavage of PARP1 protein]
CTD
PMID:11999409
NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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PAXBP1
PAX3 and PAX7 binding protein 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PAXBP1 promoter]
CTD
PMID:20348232
NCBI chr21:32,733,899...32,771,755
Ensembl chr21:32,733,899...32,771,792
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PBK
PDZ binding kinase
increases expression
ISO
Methylcholanthrene results in increased expression of PBK mRNA
CTD
PMID:20713471
NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082
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PCDH18
protocadherin 18
decreases expression
ISO
Methylcholanthrene results in decreased expression of PCDH18 mRNA
CTD
PMID:20713471
NCBI chr 4:137,518,918...137,532,494
Ensembl chr 4:137,518,918...137,532,494
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PCDH7
protocadherin 7
decreases expression
ISO
Methylcholanthrene results in decreased expression of PCDH7 mRNA
CTD
PMID:20713471
NCBI chr 4:30,720,369...31,146,800
Ensembl chr 4:30,720,369...31,146,805
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PCK1
phosphoenolpyruvate carboxykinase 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of PCK1 mRNA
CTD
PMID:11328961
NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
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PCOLCE2
procollagen C-endopeptidase enhancer 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PCOLCE2 promoter]
CTD
PMID:20348232
NCBI chr 3:142,817,874...142,889,083
Ensembl chr 3:142,815,922...142,889,206
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PDCD4
programmed cell death 4
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PDCD4 promoter]
CTD
PMID:20348232
NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006
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PDE1B
phosphodiesterase 1B
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDE1B mRNA
CTD
PMID:23519560
NCBI chr12:54,549,601...54,579,239
Ensembl chr12:54,549,601...54,579,239
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PDLIM5
PDZ and LIM domain 5
decreases expression
ISO
Methylcholanthrene results in decreased expression of PDLIM5 mRNA
CTD
PMID:20713471
NCBI chr 4:94,451,942...94,668,223
Ensembl chr 4:94,451,857...94,668,227
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PDZD8
PDZ domain containing 8
increases expression
ISO
Methylcholanthrene results in increased expression of PDZD8 mRNA
CTD
PMID:25926378
NCBI chr10:117,277,274...117,375,440
Ensembl chr10:117,277,274...117,375,440
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PELI2
pellino E3 ubiquitin protein ligase family member 2
increases expression
ISO
Methylcholanthrene results in increased expression of PELI2 mRNA
CTD
PMID:20713471
NCBI chr14:56,118,411...56,301,524
Ensembl chr14:56,117,814...56,301,524
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PF4
platelet factor 4
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of PF4 mRNA
CTD
PMID:25926378
NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027
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PGK2
phosphoglycerate kinase 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of PGK2 mRNA
CTD
PMID:35487396
NCBI chr 6:49,785,660...49,787,285
Ensembl chr 6:49,785,660...49,787,285
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PGR
progesterone receptor
increases expression multiple interactions
EXP ISO
Methylcholanthrene results in increased expression of PGR mRNA Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of PGR mRNA]; Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of PGR protein]
CTD
PMID:16257430 PMID:26372666
NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813
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PHACTR1
phosphatase and actin regulator 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PHACTR1 promoter]
CTD
PMID:20348232
NCBI chr 6:12,716,767...13,287,837
Ensembl chr 6:12,716,312...13,290,446
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PHEX
phosphate regulating endopeptidase X-linked
increases expression
ISO
Methylcholanthrene results in increased expression of PHEX mRNA
CTD
PMID:20713471
NCBI chr X:22,032,325...22,251,310
Ensembl chr X:22,032,325...22,494,713
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PHKA2
phosphorylase kinase regulatory subunit alpha 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PHKA2 mRNA
CTD
PMID:23519560
NCBI chr X:18,892,298...18,984,114
Ensembl chr X:18,892,298...18,984,114
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PIGP
phosphatidylinositol glycan anchor biosynthesis class P
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PIGP promoter]
CTD
PMID:20348232
NCBI chr21:37,065,364...37,073,071
Ensembl chr21:37,062,846...37,073,170
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PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PIK3CB mRNA
CTD
PMID:23519560
NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928
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PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PIK3CD mRNA
CTD
PMID:23519560
NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114
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PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PIK3R1 promoter]
CTD
PMID:20348232
NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821
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PIK3R5
phosphoinositide-3-kinase regulatory subunit 5
increases expression
ISO
Methylcholanthrene results in increased expression of PIK3R5 mRNA
CTD
PMID:20713471
NCBI chr17:8,878,916...8,965,707
Ensembl chr17:8,878,911...8,965,712
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PIM2
Pim-2 proto-oncogene, serine/threonine kinase
increases expression
EXP
Methylcholanthrene results in increased expression of PIM2 mRNA
CTD
PMID:22100608
NCBI chr X:48,913,182...48,919,024
Ensembl chr X:48,913,182...48,919,024
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PKNOX2
PBX/knotted 1 homeobox 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of PKNOX2 mRNA
CTD
PMID:20713471
NCBI chr11:125,164,751...125,433,389
Ensembl chr11:125,164,687...125,433,389
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PLA2G7
phospholipase A2 group VII
increases expression
ISO
Methylcholanthrene results in increased expression of PLA2G7 mRNA
CTD
PMID:20713471
NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
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PLAU
plasminogen activator, urokinase
increases expression
EXP
Methylcholanthrene results in increased expression of PLAU mRNA
CTD
PMID:16619036
NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
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PLCG2
phospholipase C gamma 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PLCG2 mRNA
CTD
PMID:23519560
NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685
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PLEKHA6
pleckstrin homology domain containing A6
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PLEKHA6 promoter]
CTD
PMID:20348232
NCBI chr 1:204,218,853...204,378,168
Ensembl chr 1:204,218,853...204,377,665
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PLEKHG2
pleckstrin homology and RhoGEF domain containing G2
decreases expression
ISO
Methylcholanthrene results in decreased expression of PLEKHG2 mRNA
CTD
PMID:20713471
NCBI chr19:39,412,669...39,428,415
Ensembl chr19:39,412,669...39,428,415
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PLK3
polo like kinase 3
increases expression
EXP
Methylcholanthrene results in increased expression of PLK3 mRNA
CTD
PMID:22100608
NCBI chr 1:44,800,377...44,805,990
Ensembl chr 1:44,800,377...44,805,990
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PLK4
polo like kinase 4
increases expression
ISO
Methylcholanthrene results in increased expression of PLK4 mRNA
CTD
PMID:20713471
NCBI chr 4:127,880,893...127,899,224
Ensembl chr 4:127,880,893...127,899,224
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PLPP3
phospholipid phosphatase 3
decreases expression
ISO
Methylcholanthrene results in decreased expression of PLPP3 mRNA
CTD
PMID:20713471
NCBI chr 1:56,494,761...56,579,563
Ensembl chr 1:56,494,761...56,645,301
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POGZ
pogo transposable element derived with ZNF domain
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to POGZ promoter]
CTD
PMID:20348232
NCBI chr 1:151,402,724...151,459,494
Ensembl chr 1:151,402,724...151,459,494
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POLA1
DNA polymerase alpha 1, catalytic subunit
increases expression
ISO
Methylcholanthrene results in increased expression of POLA1 mRNA
CTD
PMID:20713471
NCBI chr X:24,693,918...24,996,986
Ensembl chr X:24,693,873...24,996,986
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POLE2
DNA polymerase epsilon 2, accessory subunit
increases expression
ISO
Methylcholanthrene results in increased expression of POLE2 mRNA
CTD
PMID:20713471
NCBI chr14:49,643,555...49,688,214
Ensembl chr14:49,643,555...49,688,422
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POLK
DNA polymerase kappa
increases expression
EXP
Methylcholanthrene results in increased expression of POLK mRNA; Methylcholanthrene results in increased expression of POLK protein
CTD
PMID:26651356
NCBI chr 5:75,510,774...75,609,991
Ensembl chr 5:75,511,845...75,609,991
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PON1
paraoxonase 1
multiple interactions increases activity increases expression
EXP ISO
7-ketocholesterol inhibits the reaction [Methylcholanthrene results in increased expression of PON1 mRNA] Methylcholanthrene results in increased activity of PON1 protein Methylcholanthrene results in increased expression of PON1 protein
CTD
PMID:11551529 PMID:15169886 PMID:26006071
NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
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PON3
paraoxonase 3
increases expression
ISO
Methylcholanthrene results in increased expression of PON3 mRNA
CTD
PMID:26006071
NCBI chr 7:95,359,872...95,396,375
Ensembl chr 7:95,359,872...95,396,375
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POR
cytochrome p450 oxidoreductase
increases activity decreases activity multiple interactions increases expression
ISO
Methylcholanthrene results in increased activity of POR protein Methylcholanthrene results in decreased activity of POR protein sanguinarine promotes the reaction [Methylcholanthrene results in decreased activity of POR protein] Methylcholanthrene results in increased expression of POR mRNA Methylcholanthrene inhibits the reaction [POR gene mutant form results in decreased expression of CYP3A11 mRNA]; Methylcholanthrene results in increased expression of and results in increased activity of POR protein; POR gene mutant form inhibits the reaction [Methylcholanthrene affects the expression of CYP2D9 protein]; POR gene mutant form inhibits the reaction [Methylcholanthrene results in decreased expression of MUP2 mRNA]; POR gene mutant form inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]
CTD
PMID:19788401 PMID:22978700 PMID:23169610 PMID:23846873
NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855
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POSTN
periostin
decreases expression
ISO
Methylcholanthrene results in decreased expression of POSTN mRNA
CTD
PMID:20713471
NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844
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POTEB
POTE ankyrin domain family member B
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to POTEB promoter]
CTD
PMID:20348232
NCBI chr15:21,846,329...21,877,735
Ensembl chr15:21,846,329...21,877,735
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PPARA
peroxisome proliferator activated receptor alpha
increases expression
ISO
Methylcholanthrene results in increased expression of PPARA mRNA
CTD
PMID:23273579
NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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PPBP
pro-platelet basic protein
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PPBP mRNA
CTD
PMID:23519560
NCBI chr 4:73,986,439...73,988,190
Ensembl chr 4:73,986,439...73,988,190
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PPIAL4A
peptidylprolyl isomerase A like 4A
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PPIAL4A promoter]
CTD
PMID:20348232
NCBI chr 1:120,889,771...120,890,530
Ensembl chr 1:120,889,771...120,890,530
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PPIH
peptidylprolyl isomerase H
increases expression
ISO
Methylcholanthrene results in increased expression of PPIH mRNA
CTD
PMID:20713471
NCBI chr 1:42,658,423...42,681,654
Ensembl chr 1:42,658,335...42,676,758
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PPM1D
protein phosphatase, Mg2+/Mn2+ dependent 1D
increases expression
EXP
Methylcholanthrene results in increased expression of PPM1D mRNA
CTD
PMID:22100608
NCBI chr17:60,600,193...60,666,280
Ensembl chr17:60,600,193...60,666,280
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PPP4R2
protein phosphatase 4 regulatory subunit 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of PPP4R2 mRNA
CTD
PMID:25926378
NCBI chr 3:72,996,743...73,069,198
Ensembl chr 3:72,996,803...73,069,198
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PRC1
protein regulator of cytokinesis 1
increases expression
ISO
Methylcholanthrene results in increased expression of PRC1 mRNA
CTD
PMID:20713471
NCBI chr15:90,966,040...90,994,535
Ensembl chr15:90,966,040...90,995,629
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PRDM9
PR/SET domain 9
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of PRDM9 mRNA
CTD
PMID:25926378
NCBI chr 5:23,507,155...23,528,093
Ensembl chr 5:23,443,586...23,528,093
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PREX1
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PREX1 mRNA
CTD
PMID:23519560
NCBI chr20:48,624,252...48,888,185
Ensembl chr20:48,624,252...48,827,999
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PRICKLE2
prickle planar cell polarity protein 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of PRICKLE2 mRNA
CTD
PMID:20713471
NCBI chr 3:64,092,236...64,268,173
Ensembl chr 3:64,092,236...64,445,476
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PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PRKAB1 promoter]
CTD
PMID:20348232
NCBI chr12:119,667,952...119,681,619
Ensembl chr12:119,667,864...119,681,624
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PRKAB2
protein kinase AMP-activated non-catalytic subunit beta 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PRKAB2 promoter]
CTD
PMID:20348232
NCBI chr 1:147,155,106...147,172,470
Ensembl chr 1:147,155,106...147,172,550
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PRKD3
protein kinase D3
decreases expression
ISO
Methylcholanthrene results in decreased expression of PRKD3 mRNA
CTD
PMID:20713471
NCBI chr 2:37,250,502...37,324,833
Ensembl chr 2:37,250,502...37,324,833
G
PRPS1
phosphoribosyl pyrophosphate synthetase 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PRPS1 promoter]
CTD
PMID:20348232
NCBI chr X:107,628,510...107,651,026
Ensembl chr X:107,628,428...107,651,993
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PSG5
pregnancy specific beta-1-glycoprotein 5
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PSG5 promoter]
CTD
PMID:20348232
NCBI chr19:43,167,743...43,186,536
Ensembl chr19:43,166,256...43,186,536
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PSG9
pregnancy specific beta-1-glycoprotein 9
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PSG9 promoter]
CTD
PMID:20348232
NCBI chr19:43,253,282...43,269,530
Ensembl chr19:43,211,791...43,269,530
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PSMB5
proteasome 20S subunit beta 5
increases activity multiple interactions increases expression
ISO
Methylcholanthrene results in increased activity of PSMB5 protein NFE2L2 protein affects the reaction [Methylcholanthrene results in increased expression of PSMB5 mRNA] Methylcholanthrene results in increased expression of PSMB5 mRNA; Methylcholanthrene results in increased expression of PSMB5 protein
CTD
PMID:16723119
NCBI chr14:23,025,851...23,035,220
Ensembl chr14:23,016,543...23,035,230
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PSMB6
proteasome 20S subunit beta 6
increases expression
ISO
Methylcholanthrene results in increased expression of PSMB6 protein
CTD
PMID:16723119
NCBI chr17:4,796,164...4,798,495
Ensembl chr17:4,796,144...4,798,502
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PSMB7
proteasome 20S subunit beta 7
increases expression
ISO
Methylcholanthrene results in increased expression of PSMB7 protein
CTD
PMID:16723119
NCBI chr 9:124,353,465...124,415,442
Ensembl chr 9:124,353,465...124,415,444
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PSMB8
proteasome 20S subunit beta 8
increases expression
ISO
Methylcholanthrene results in increased expression of PSMB8 mRNA
CTD
PMID:29554273
NCBI chr 6:32,840,717...32,844,679
Ensembl chr 6:32,840,717...32,844,679
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PSME2
proteasome activator subunit 2
increases expression
ISO
Methylcholanthrene results in increased expression of PSME2 mRNA
CTD
PMID:29554273
NCBI chr14:24,143,365...24,146,610
Ensembl chr14:24,143,362...24,147,570
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PSRC1
proline and serine rich coiled-coil 1
increases expression
ISO
Methylcholanthrene results in increased expression of PSRC1 mRNA
CTD
PMID:20713471
NCBI chr 1:109,279,556...109,283,145
Ensembl chr 1:109,279,556...109,283,186
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PTER
phosphotriesterase related
increases expression
ISO
Methylcholanthrene results in increased expression of PTER mRNA
CTD
PMID:20713471
NCBI chr10:16,437,010...16,519,020
Ensembl chr10:16,436,943...16,513,745
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PTGER4
prostaglandin E receptor 4
increases expression
ISO
Methylcholanthrene results in increased expression of PTGER4 mRNA
CTD
PMID:25926378
NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735
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PTGES
prostaglandin E synthase
increases expression
ISO
Methylcholanthrene results in increased expression of PTGES mRNA
CTD
PMID:20713471
NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
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PTGFR
prostaglandin F receptor
decreases expression multiple interactions
ISO
Methylcholanthrene results in decreased expression of PTGFR mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTGFR mRNA
CTD
PMID:20713471 PMID:23519560
NCBI chr 1:78,490,974...78,540,701
Ensembl chr 1:78,303,884...78,540,701
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PTGS1
prostaglandin-endoperoxide synthase 1
increases expression
ISO
Methylcholanthrene results in increased expression of PTGS1 mRNA
CTD
PMID:20713471
NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
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PTGS2
prostaglandin-endoperoxide synthase 2
increases expression
ISO EXP
Methylcholanthrene results in increased expression of PTGS2 mRNA
CTD
PMID:20713471 PMID:28601433
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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PTK2
protein tyrosine kinase 2
multiple interactions decreases phosphorylation
EXP
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased phosphorylation of PTK2 protein]
CTD
PMID:16359657
NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
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PTN
pleiotrophin
decreases expression
ISO
Methylcholanthrene results in decreased expression of PTN mRNA
CTD
PMID:20713471
NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774
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PTTG1
PTTG1 regulator of sister chromatid separation, securin
increases expression
ISO
Methylcholanthrene results in increased expression of PTTG1 mRNA
CTD
PMID:20713471
NCBI chr 5:160,421,855...160,428,744
Ensembl chr 5:160,421,855...160,428,739
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PTX3
pentraxin 3
increases expression
ISO
Methylcholanthrene results in increased expression of PTX3 mRNA
CTD
PMID:29554273
NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633
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PWWP3A
PWWP domain containing 3A, DNA repair factor
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to PWWP3A promoter]
CTD
PMID:20348232
NCBI chr19:1,354,959...1,378,429
Ensembl chr19:1,354,711...1,378,431
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PXYLP1
2-phosphoxylose phosphatase 1
increases expression
ISO
Methylcholanthrene results in increased expression of PXYLP1 mRNA
CTD
PMID:20713471
NCBI chr 3:141,231,825...141,294,924
Ensembl chr 3:141,228,726...141,367,753
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RABL2A
RAB, member of RAS oncogene family like 2A
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RABL2A promoter]
CTD
PMID:20348232
NCBI chr 2:113,627,266...113,643,392
Ensembl chr 2:113,627,229...113,643,396
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RAC1
Rac family small GTPase 1
increases expression
ISO
Methylcholanthrene results in increased expression of RAC1 mRNA
CTD
PMID:29554273
NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
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RACGAP1
Rac GTPase activating protein 1
increases expression
ISO
Methylcholanthrene results in increased expression of RACGAP1 mRNA
CTD
PMID:20713471
NCBI chr12:49,989,162...50,033,440
Ensembl chr12:49,976,923...50,033,136
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RAD51
RAD51 recombinase
increases expression
ISO
Methylcholanthrene results in increased expression of RAD51 mRNA
CTD
PMID:20713471
NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340
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RAD51AP1
RAD51 associated protein 1
increases expression
ISO
Methylcholanthrene results in increased expression of RAD51AP1 mRNA
CTD
PMID:20713471
NCBI chr12:4,538,890...4,560,047
Ensembl chr12:4,538,798...4,560,047
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RAD54L
RAD54 like
increases expression
ISO
Methylcholanthrene results in increased expression of RAD54L mRNA
CTD
PMID:20713471
NCBI chr 1:46,247,688...46,278,473
Ensembl chr 1:46,246,461...46,278,480
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RALGAPA2
Ral GTPase activating protein catalytic subunit alpha 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RALGAPA2 promoter]
CTD
PMID:20348232
NCBI chr20:20,389,530...20,712,644
Ensembl chr20:20,389,530...20,712,644
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RANBP2
RAN binding protein 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RANBP2 promoter]
CTD
PMID:20348232
NCBI chr 2:108,719,482...109,842,301
Ensembl chr 2:108,719,482...108,785,810
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RASAL3
RAS protein activator like 3
increases expression
ISO
Methylcholanthrene results in increased expression of RASAL3 mRNA
CTD
PMID:25926378
NCBI chr19:15,451,624...15,464,544
Ensembl chr19:15,451,624...15,464,544
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RASSF1
Ras association domain family member 1
multiple interactions
ISO
[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of RASSF1 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of RASSF1 promoter
CTD
PMID:20970405
NCBI chr 3:50,329,788...50,340,836
Ensembl chr 3:50,329,782...50,340,980
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RBBP7
RB binding protein 7, chromatin remodeling factor
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RBBP7 promoter]
CTD
PMID:20348232
NCBI chr X:16,844,341...16,870,362
Ensembl chr X:16,839,283...16,870,362
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RBM24
RNA binding motif protein 24
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RBM24 promoter]
CTD
PMID:20348232
NCBI chr 6:17,281,361...17,293,871
Ensembl chr 6:17,281,361...17,293,871
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RBMS2
RNA binding motif single stranded interacting protein 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RBMS2 promoter]
CTD
PMID:20348232
NCBI chr12:56,520,405...56,596,193
Ensembl chr12:56,521,820...56,596,193
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RBMS3
RNA binding motif single stranded interacting protein 3
decreases expression
ISO
Methylcholanthrene results in decreased expression of RBMS3 mRNA
CTD
PMID:20713471
NCBI chr 3:29,281,071...30,010,395
Ensembl chr 3:28,574,791...30,010,391
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RBPJ
recombination signal binding protein for immunoglobulin kappa J region
increases expression
ISO
Methylcholanthrene results in increased expression of RBPJ mRNA
CTD
PMID:20713471
NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131
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RBSN
rabenosyn, RAB effector
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RBSN promoter]
CTD
PMID:20348232
NCBI chr 3:15,070,073...15,099,148
Ensembl chr 3:15,070,073...15,099,163
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RERG
RAS like estrogen regulated growth inhibitor
multiple interactions decreases expression
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RERG promoter] Methylcholanthrene results in decreased expression of RERG mRNA
CTD
PMID:20348232
NCBI chr12:15,107,783...15,221,417
Ensembl chr12:15,107,783...15,348,675
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RFC3
replication factor C subunit 3
increases expression
ISO
Methylcholanthrene results in increased expression of RFC3 mRNA
CTD
PMID:20713471
NCBI chr13:33,818,149...33,977,377
Ensembl chr13:33,818,069...33,966,558
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RFC4
replication factor C subunit 4
increases expression
ISO
Methylcholanthrene results in increased expression of RFC4 mRNA
CTD
PMID:20713471
NCBI chr 3:186,789,900...186,806,482
Ensembl chr 3:186,789,880...186,807,058
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RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RFFL promoter]
CTD
PMID:20348232
NCBI chr17:35,005,990...35,089,226
Ensembl chr17:35,005,990...35,089,319
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RGPD5
RANBP2 like and GRIP domain containing 5
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RGPD5 promoter]
CTD
PMID:20348232
NCBI chr 2:109,760,618...109,857,705
Ensembl chr 2:109,792,758...109,857,705
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RGPD6
RANBP2 like and GRIP domain containing 6
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RGPD6 promoter]
CTD
PMID:20348232
NCBI chr 2:110,513,802...110,611,056
Ensembl chr 2:110,513,802...110,610,840
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RGS3
regulator of G protein signaling 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RGS3 promoter]
CTD
PMID:20348232
NCBI chr 9:113,444,730...113,597,738
Ensembl chr 9:113,444,731...113,597,743
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RHOBTB1
Rho related BTB domain containing 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RHOBTB1 promoter]
CTD
PMID:20348232
NCBI chr10:60,860,860...61,001,967
Ensembl chr10:60,869,438...61,001,440
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RHOC
ras homolog family member C
increases expression
EXP
Methylcholanthrene results in increased expression of RHOC mRNA
CTD
PMID:22579512
NCBI chr 1:112,701,131...112,707,408
Ensembl chr 1:112,701,127...112,707,434
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RHOH
ras homolog family member H
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RHOH promoter]
CTD
PMID:20348232
NCBI chr 4:40,191,080...40,246,967
Ensembl chr 4:40,191,011...40,246,967
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RIN3
Ras and Rab interactor 3
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of RIN3 mRNA
CTD
PMID:25926378
NCBI chr14:92,513,781...92,688,994
Ensembl chr14:92,513,781...92,688,994
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RND3
Rho family GTPase 3
decreases expression
ISO
Methylcholanthrene results in decreased expression of RND3 mRNA
CTD
PMID:20713471
NCBI chr 2:150,468,193...150,487,695
Ensembl chr 2:150,468,195...150,539,011
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RNF157
ring finger protein 157
decreases expression
ISO
Methylcholanthrene results in decreased expression of RNF157 mRNA
CTD
PMID:20713471
NCBI chr17:76,142,474...76,240,493
Ensembl chr17:76,142,465...76,240,493
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ROBO1
roundabout guidance receptor 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of ROBO1 mRNA
CTD
PMID:20713471
NCBI chr 3:78,597,239...79,767,998
Ensembl chr 3:78,597,239...79,767,998
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ROR1
receptor tyrosine kinase like orphan receptor 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of ROR1 mRNA
CTD
PMID:20713471
NCBI chr 1:63,774,017...64,181,498
Ensembl chr 1:63,774,017...64,181,498
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RPA2
replication protein A2
increases expression
ISO
Methylcholanthrene results in increased expression of RPA2 mRNA
CTD
PMID:20713471
NCBI chr 1:27,891,524...27,914,797
Ensembl chr 1:27,891,524...27,914,746
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RPL11
ribosomal protein L11
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RPL11 promoter]
CTD
PMID:20348232
NCBI chr 1:23,691,779...23,696,835
Ensembl chr 1:23,691,742...23,696,835
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RRM1
ribonucleotide reductase catalytic subunit M1
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of RRM1 mRNA
CTD
PMID:25926378
NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932
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RRM2
ribonucleotide reductase regulatory subunit M2
increases expression
ISO
Methylcholanthrene results in increased expression of RRM2 mRNA
CTD
PMID:20713471
NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725
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RSAD2
radical S-adenosyl methionine domain containing 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of RSAD2 mRNA
CTD
PMID:20713471
NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239
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RTN3
reticulon 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RTN3 promoter]
CTD
PMID:20348232
NCBI chr11:63,681,450...63,759,891
Ensembl chr11:63,681,446...63,759,891
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RTP4
receptor transporter protein 4
decreases expression
ISO
Methylcholanthrene results in decreased expression of RTP4 mRNA
CTD
PMID:20713471
NCBI chr 3:187,368,385...187,372,076
Ensembl chr 3:187,368,385...187,372,076
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RXRA
retinoid X receptor alpha
increases expression
ISO
Methylcholanthrene results in increased expression of RXRA mRNA
CTD
PMID:23273579
NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
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RYR3
ryanodine receptor 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to RYR3 promoter]
CTD
PMID:20348232
NCBI chr15:33,310,967...33,866,102
Ensembl chr15:33,310,962...33,866,121
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S100P
S100 calcium binding protein P
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to S100P promoter]
CTD
PMID:20348232
NCBI chr 4:6,693,878...6,697,170
Ensembl chr 4:6,693,878...6,697,170
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SAMD12
sterile alpha motif domain containing 12
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SAMD12 promoter]
CTD
PMID:20348232
NCBI chr 8:118,131,825...118,621,963
Ensembl chr 8:118,189,455...118,622,112
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SAP30BP
SAP30 binding protein
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of SAP30BP mRNA
CTD
PMID:25926378
NCBI chr17:75,667,338...75,708,059
Ensembl chr17:75,667,251...75,708,062
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SBNO1
strawberry notch homolog 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of SBNO1 mRNA
CTD
PMID:25926378
NCBI chr12:123,289,109...123,364,847
Ensembl chr12:123,289,109...123,364,847
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SCAI
suppressor of cancer cell invasion
decreases expression
ISO
Methylcholanthrene results in decreased expression of SCAI mRNA
CTD
PMID:25926378
NCBI chr 9:124,942,608...125,143,528
Ensembl chr 9:124,942,608...125,143,528
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SCAMP2
secretory carrier membrane protein 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of SCAMP2 mRNA
CTD
PMID:25926378
NCBI chr15:74,843,730...74,873,365
Ensembl chr15:74,843,730...74,873,365
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SCN3B
sodium voltage-gated channel beta subunit 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SCN3B promoter]
CTD
PMID:20348232
NCBI chr11:123,629,188...123,654,624
Ensembl chr11:123,629,187...123,655,244
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SELP
selectin P
increases expression
ISO
Methylcholanthrene results in increased expression of SELP mRNA
CTD
PMID:29554273
NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193
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SEMA5A
semaphorin 5A
increases expression
ISO
Methylcholanthrene results in increased expression of SEMA5A mRNA
CTD
PMID:20713471
NCBI chr 5:9,035,033...9,546,075
Ensembl chr 5:9,035,033...9,546,075
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SEMA6D
semaphorin 6D
increases expression
ISO
Methylcholanthrene results in increased expression of SEMA6D mRNA
CTD
PMID:20713471
NCBI chr15:47,184,089...47,774,228
Ensembl chr15:47,184,101...47,774,228
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SEMA7A
semaphorin 7A (JohnMiltonHagen blood group)
increases expression
ISO
Methylcholanthrene results in increased expression of SEMA7A mRNA
CTD
PMID:20713471
NCBI chr15:74,409,289...74,433,958
Ensembl chr15:74,409,289...74,433,958
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SERPINE1
serpin family E member 1
increases expression
EXP
Methylcholanthrene results in increased expression of SERPINE1 mRNA
CTD
PMID:16619036
NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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SFRP1
secreted frizzled related protein 1
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFRP1 mRNA
CTD
PMID:23519560
NCBI chr 8:41,261,962...41,309,473
Ensembl chr 8:41,261,962...41,309,473
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SFRP2
secreted frizzled related protein 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFRP2 mRNA
CTD
PMID:23519560
NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
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SFTPD
surfactant protein D
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFTPD mRNA
CTD
PMID:23519560
NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614
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SGO1
shugoshin 1
increases expression
ISO
Methylcholanthrene results in increased expression of SGO1 mRNA
CTD
PMID:20713471
NCBI chr 3:20,160,593...20,186,886
Ensembl chr 3:20,160,593...20,186,206
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SHC4
SHC adaptor protein 4
increases expression
ISO
Methylcholanthrene results in increased expression of SHC4 mRNA
CTD
PMID:20713471
NCBI chr15:48,823,741...48,963,919
Ensembl chr15:48,823,741...48,963,919
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SHCBP1
SHC binding and spindle associated 1
increases expression
ISO
Methylcholanthrene results in increased expression of SHCBP1 mRNA
CTD
PMID:20713471
NCBI chr16:46,578,591...46,621,379
Ensembl chr16:46,578,591...46,621,379
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SIK3
SIK family kinase 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SIK3 promoter]
CTD
PMID:20348232
NCBI chr11:116,843,402...117,098,428
Ensembl chr11:116,843,402...117,098,437
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SIRT2
sirtuin 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of SIRT2 mRNA
CTD
PMID:25926378
NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862
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SIVA1
SIVA1 apoptosis inducing factor
increases expression
ISO
Methylcholanthrene results in increased expression of SIVA1 mRNA
CTD
PMID:20713471
NCBI chr14:104,753,147...104,759,654
Ensembl chr14:104,753,147...104,768,494
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SKIC8
SKI8 subunit of superkiller complex
increases expression
ISO
Methylcholanthrene results in increased expression of SKIC8 mRNA
CTD
PMID:20713471
NCBI chr15:78,283,235...78,299,609
Ensembl chr15:78,277,835...78,299,703
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SLC13A5
solute carrier family 13 member 5
increases expression
ISO
Methylcholanthrene results in increased expression of SLC13A5 mRNA
CTD
PMID:26303333
NCBI chr17:6,684,719...6,713,369
Ensembl chr17:6,684,719...6,713,377
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SLC15A2
solute carrier family 15 member 2
increases expression
ISO
Methylcholanthrene results in increased expression of SLC15A2 mRNA
CTD
PMID:25926378
NCBI chr 3:121,894,401...121,944,188
Ensembl chr 3:121,894,401...121,944,188
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SLC16A6
solute carrier family 16 member 6
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SLC16A6 promoter]
CTD
PMID:20348232
NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267
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SLC22A23
solute carrier family 22 member 23
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SLC22A23 promoter]
CTD
PMID:20348232
NCBI chr 6:3,268,973...3,457,050
Ensembl chr 6:3,268,962...3,457,050
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SLC23A1
solute carrier family 23 member 1
increases expression
ISO
Methylcholanthrene results in increased expression of SLC23A1 mRNA
CTD
PMID:21800402
NCBI chr 5:139,367,196...139,385,676
Ensembl chr 5:139,367,196...139,384,553
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SLC27A1
solute carrier family 27 member 1
increases expression
ISO
Methylcholanthrene results in increased expression of SLC27A1 mRNA
CTD
PMID:20713471
NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168
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SLC2A1
solute carrier family 2 member 1
increases expression
ISO
Methylcholanthrene results in increased expression of SLC2A1 mRNA
CTD
PMID:21800402
NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
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SLC44A1
solute carrier family 44 member 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SLC44A1 promoter]
CTD
PMID:20348232
NCBI chr 9:105,244,651...105,438,504
Ensembl chr 9:105,244,622...105,439,171
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SLC9A9
solute carrier family 9 member A9
decreases expression
ISO
Methylcholanthrene results in decreased expression of SLC9A9 mRNA
CTD
PMID:20713471
NCBI chr 3:143,265,222...143,848,468
Ensembl chr 3:143,265,222...143,848,485
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SLCO1B3
solute carrier organic anion transporter family member 1B3
increases expression
ISO
Methylcholanthrene results in increased expression of SLCO1B2 mRNA
CTD
PMID:27160211
NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911
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SLF2
SMC5-SMC6 complex localization factor 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of SLF2 mRNA
CTD
PMID:25926378
NCBI chr10:100,912,963...100,965,134
Ensembl chr10:100,912,963...100,965,134
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SLIT2
slit guidance ligand 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of SLIT2 mRNA
CTD
PMID:20713471
NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561
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SLU7
SLU7 homolog, splicing factor
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SLU7 promoter]
CTD
PMID:20348232
NCBI chr 5:160,401,641...160,419,081
Ensembl chr 5:160,401,641...160,421,711
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SMAP2
small ArfGAP2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SMAP2 promoter]
CTD
PMID:20348232
NCBI chr 1:40,344,834...40,423,326
Ensembl chr 1:40,344,850...40,423,326
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SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SMARCE1 promoter]
CTD
PMID:20348232
NCBI chr17:40,624,962...40,647,818
Ensembl chr17:40,624,962...40,648,654
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SMYD3
SET and MYND domain containing 3
decreases expression
EXP
Methylcholanthrene results in decreased expression of SMYD3 mRNA
CTD
PMID:22100608
NCBI chr 1:245,749,347...246,507,279
Ensembl chr 1:245,749,342...246,507,312
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SNAPIN
SNAP associated protein
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SNAPIN promoter]
CTD
PMID:20348232
NCBI chr 1:153,658,654...153,661,852
Ensembl chr 1:153,658,703...153,661,852
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SNORD116-9
small nucleolar RNA, C/D box 116-9
multiple interactions decreases expression
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of SNORD116 mRNA Methylcholanthrene results in decreased expression of SNORD116 mRNA
CTD
PMID:25926378
NCBI chr15:25,073,106...25,073,202
Ensembl chr15:25,073,107...25,073,201
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SOCS2
suppressor of cytokine signaling 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of SOCS2 mRNA
CTD
PMID:25926378
NCBI chr12:93,569,969...93,626,236
Ensembl chr12:93,569,814...93,583,487
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SOCS3
suppressor of cytokine signaling 3
multiple interactions increases expression
ISO
[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of SOCS3 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of SOCS3 promoter Methylcholanthrene results in increased expression of SOCS3 mRNA
CTD
PMID:20970405 PMID:23169610
NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
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SOCS7
suppressor of cytokine signaling 7
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SOCS7 promoter]
CTD
PMID:20348232
NCBI chr17:38,351,844...38,405,593
Ensembl chr17:38,351,844...38,405,593
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SOD1
superoxide dismutase 1
increases expression
ISO
Methylcholanthrene results in increased expression of SOD1 mRNA
CTD
PMID:23273579 PMID:23712962
NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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SOD2
superoxide dismutase 2
increases expression decreases expression
ISO
Methylcholanthrene results in increased expression of SOD2 mRNA Methylcholanthrene results in decreased expression of SOD2 mRNA
CTD
PMID:23712962 PMID:35487396
NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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SORL1
sortilin related receptor 1
multiple interactions increases expression
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SORL1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to SORL1 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of SORL1 mRNA]
CTD
PMID:20348232
NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763
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SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1
increases expression multiple interactions
EXP
Methylcholanthrene results in increased expression of SOS1 mRNA Methylcholanthrene promotes the reaction [AHR protein binds to SOS1 promoter]
CTD
PMID:16619036 PMID:20348232
NCBI chr 2:38,981,549...39,124,868
Ensembl chr 2:38,962,206...39,124,345
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SOX17
SRY-box transcription factor 17
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOX17 mRNA
CTD
PMID:23519560
NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892
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SOX4
SRY-box transcription factor 4
decreases expression
ISO
Methylcholanthrene results in decreased expression of SOX4 mRNA
CTD
PMID:20713471
NCBI chr 6:21,593,751...21,598,619
Ensembl chr 6:21,593,751...21,598,619
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SP1
Sp1 transcription factor
multiple interactions increases acetylation increases expression
ISO
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of SP1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of SP1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]
CTD
PMID:29094188
NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446
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SP140L
SP140 nuclear body protein like
decreases expression
ISO
Methylcholanthrene results in decreased expression of SP140 mRNA
CTD
PMID:25926378
NCBI chr 2:230,327,193...230,403,732
Ensembl chr 2:230,327,184...230,403,732
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SPAG5
sperm associated antigen 5
increases expression
ISO
Methylcholanthrene results in increased expression of SPAG5 mRNA
CTD
PMID:20713471
NCBI chr17:28,577,574...28,599,025
Ensembl chr17:28,577,565...28,599,025
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SPARCL1
SPARC like 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of SPARCL1 mRNA
CTD
PMID:20713471
NCBI chr 4:87,473,335...87,529,376
Ensembl chr 4:87,473,335...87,531,061
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SPC24
SPC24 component of NDC80 kinetochore complex
increases expression
ISO
Methylcholanthrene results in increased expression of SPC24 mRNA
CTD
PMID:20713471
NCBI chr19:11,145,493...11,155,782
Ensembl chr19:11,131,520...11,155,807
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SPC25
SPC25 component of NDC80 kinetochore complex
increases expression
ISO
Methylcholanthrene results in increased expression of SPC25 mRNA
CTD
PMID:20713471
NCBI chr 2:168,861,521...168,890,430
Ensembl chr 2:168,834,132...168,913,371
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SPDL1
spindle apparatus coiled-coil protein 1
increases expression
ISO
Methylcholanthrene results in increased expression of SPDL1 mRNA
CTD
PMID:20713471
NCBI chr 5:169,583,773...169,604,778
Ensembl chr 5:169,583,636...169,604,778
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SPIB
Spi-B transcription factor
increases expression
ISO
Methylcholanthrene results in increased expression of SPIB mRNA
CTD
PMID:25926378
NCBI chr19:50,418,938...50,431,314
Ensembl chr19:50,418,938...50,431,314
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SPON2
spondin 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SPON2 promoter]
CTD
PMID:20348232
NCBI chr 4:1,166,932...1,208,844
Ensembl chr 4:1,166,932...1,208,962
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SPRED1
sprouty related EVH1 domain containing 1
increases expression multiple interactions
ISO EXP
Methylcholanthrene results in increased expression of SPRED1 mRNA Methylcholanthrene promotes the reaction [AHR protein binds to SPRED1 promoter]
CTD
PMID:20348232 PMID:20713471
NCBI chr15:38,252,836...38,357,249
Ensembl chr15:38,252,836...38,357,249
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SPRED2
sprouty related EVH1 domain containing 2
increases expression
ISO
Methylcholanthrene results in increased expression of SPRED2 mRNA
CTD
PMID:20713471
NCBI chr 2:65,307,175...65,432,599
Ensembl chr 2:65,310,851...65,432,637
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SPRY2
sprouty RTK signaling antagonist 2
increases expression
ISO
Methylcholanthrene results in increased expression of SPRY2 mRNA
CTD
PMID:20713471
NCBI chr13:80,335,976...80,341,126
Ensembl chr13:80,335,976...80,341,126
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SPTLC1
serine palmitoyltransferase long chain base subunit 1
affects localization decreases response to substance multiple interactions
EXP
Methylcholanthrene affects the localization of SPTLC1 protein SPTLC1 protein mutant form results in decreased susceptibility to Methylcholanthrene; SPTLC1 protein results in decreased susceptibility to Methylcholanthrene SPTLC1 protein inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; SPTLC1 protein mutant form inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]
CTD
PMID:16968971
NCBI chr 9:92,031,147...92,115,413
Ensembl chr 9:92,000,087...92,115,413
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SPTLC2
serine palmitoyltransferase long chain base subunit 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SPTLC2 promoter]
CTD
PMID:20348232
NCBI chr14:77,505,997...77,616,637
Ensembl chr14:77,505,997...77,616,637
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SPTSSA
serine palmitoyltransferase small subunit A
decreases expression
ISO
Methylcholanthrene results in decreased expression of SPTSSA mRNA
CTD
PMID:25926378
NCBI chr14:34,432,788...34,462,240
Ensembl chr14:34,432,788...34,462,240
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SRC
SRC proto-oncogene, non-receptor tyrosine kinase
multiple interactions affects expression
ISO
Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [SRC protein binds to AHR protein]] Methylcholanthrene affects the expression of SRC mRNA
CTD
PMID:8937476 PMID:23273579
NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
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SRSF1
serine and arginine rich splicing factor 1
multiple interactions
ISO
[Butylated Hydroxytoluene co-treated with Methylcholanthrene] affects the localization of SRSF1 protein; [Butylated Hydroxytoluene co-treated with Methylcholanthrene] results in increased expression of SRSF1 protein
CTD
PMID:15390079
NCBI chr17:57,989,038...58,007,246
Ensembl chr17:58,000,919...58,007,346
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SS18
SS18 subunit of BAF chromatin remodeling complex
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SS18 promoter]
CTD
PMID:20348232
NCBI chr18:26,016,253...26,091,219
Ensembl chr18:26,016,253...26,091,217
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STAR
steroidogenic acute regulatory protein
increases expression
ISO
Methylcholanthrene results in increased expression of STAR mRNA
CTD
PMID:35487396
NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
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STARD13
StAR related lipid transfer domain containing 13
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to STARD13 promoter]
CTD
PMID:20348232
NCBI chr13:33,103,137...33,676,794
Ensembl chr13:33,103,137...33,350,630
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STAT2
signal transducer and activator of transcription 2
increases expression
ISO
Methylcholanthrene results in increased expression of STAT2 mRNA
CTD
PMID:29554273
NCBI chr12:56,341,597...56,360,107
Ensembl chr12:56,341,597...56,360,203
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STAT3
signal transducer and activator of transcription 3
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of STAT3 mRNA
CTD
PMID:25926378
NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
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STAT5B
signal transducer and activator of transcription 5B
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to STAT5B promoter]
CTD
PMID:20348232
NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633
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STAU2
staufen double-stranded RNA binding protein 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of STAU2 mRNA
CTD
PMID:20713471
NCBI chr 8:73,420,369...73,747,480
Ensembl chr 8:73,420,369...73,747,708
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STMN1
stathmin 1
increases expression
ISO
Methylcholanthrene results in increased expression of STMN1 mRNA
CTD
PMID:20713471
NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991
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STYK1
serine/threonine/tyrosine kinase 1
increases expression
ISO
Methylcholanthrene results in increased expression of STYK1 mRNA
CTD
PMID:20713471
NCBI chr12:10,618,923...10,674,052
Ensembl chr12:10,618,923...10,674,318
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SULT1A1
sulfotransferase family 1A member 1
decreases expression multiple interactions
ISO EXP
Methylcholanthrene results in decreased expression of SULT1A1 mRNA [Methylcholanthrene co-treated with Oxygen deficiency] results in decreased expression of SULT1A1 mRNA
CTD
PMID:11323195 PMID:33811995
NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044
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SULT1E1
sulfotransferase family 1E member 1
decreases expression
EXP
Methylcholanthrene results in decreased expression of SULT1E1 mRNA
CTD
PMID:33811995
NCBI chr 4:69,821,122...69,860,145
Ensembl chr 4:69,841,212...69,860,145
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SULT2A1
sulfotransferase family 2A member 1
decreases expression
ISO
Methylcholanthrene results in decreased expression of SULT2A1 mRNA
CTD
PMID:9566755
NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315
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SWSAP1
SWIM-type zinc finger 7 associated protein 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SWSAP1 promoter]
CTD
PMID:20348232
NCBI chr19:11,374,666...11,376,169
Ensembl chr19:11,374,666...11,376,951
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SYCP2
synaptonemal complex protein 2
multiple interactions increases expression
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SYCP2 promoter] Methylcholanthrene results in increased expression of SYCP2 mRNA
CTD
PMID:20348232
NCBI chr20:59,863,571...59,933,637
Ensembl chr20:59,863,564...59,933,655
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SYCP3
synaptonemal complex protein 3
decreases expression
ISO
Methylcholanthrene results in decreased expression of SYCP3 mRNA
CTD
PMID:35487396
NCBI chr12:101,728,648...101,739,462
Ensembl chr12:101,728,648...101,739,472
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SYNM
synemin
decreases expression
ISO
Methylcholanthrene results in decreased expression of SYNM mRNA
CTD
PMID:20713471
NCBI chr15:99,105,080...99,141,767
Ensembl chr15:99,098,217...99,135,593
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SYT12
synaptotagmin 12
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to SYT12 promoter]
CTD
PMID:20348232
NCBI chr11:67,006,771...67,050,863
Ensembl chr11:67,006,778...67,050,863
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TANK
TRAF family member associated NFKB activator
increases expression
ISO
Methylcholanthrene results in increased expression of TANK mRNA
CTD
PMID:23273579
NCBI chr 2:161,136,963...161,236,230
Ensembl chr 2:161,136,908...161,236,230
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TAP1
transporter 1, ATP binding cassette subfamily B member
increases expression
ISO
Methylcholanthrene results in increased expression of TAP1 mRNA
CTD
PMID:29554273
NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816
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TAP2
transporter 2, ATP binding cassette subfamily B member
increases expression
ISO
Methylcholanthrene results in increased expression of TAP2 mRNA
CTD
PMID:29554273
NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739
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TBL1XR1
TBL1X/Y related 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TBL1XR1 promoter]
CTD
PMID:20348232
NCBI chr 3:177,019,344...177,201,800
Ensembl chr 3:177,019,340...177,228,000
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TBX3
T-box transcription factor 3
increases expression
EXP
Methylcholanthrene results in increased expression of TBX3 mRNA
CTD
PMID:23397585
NCBI chr12:114,670,255...114,684,175
Ensembl chr12:114,670,255...114,684,175
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TCF19
transcription factor 19
increases expression
ISO
Methylcholanthrene results in increased expression of TCF19 mRNA
CTD
PMID:20713471
NCBI chr 6:31,158,589...31,164,215
Ensembl chr 6:31,158,331...31,167,159
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TEAD4
TEA domain transcription factor 4
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TEAD4 promoter]
CTD
PMID:20348232
NCBI chr12:2,959,397...3,040,676
Ensembl chr12:2,959,330...3,040,676
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TFF1
trefoil factor 1
increases expression
EXP
Methylcholanthrene results in increased expression of TFF1 mRNA
CTD
PMID:16257430
NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535
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TFF3
trefoil factor 3
decreases expression
ISO
Methylcholanthrene results in decreased expression of TFF3 mRNA
CTD
PMID:29554273
NCBI chr21:42,311,667...42,315,409
Ensembl chr21:42,311,667...42,315,409
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THBD
thrombomodulin
increases expression
ISO
Methylcholanthrene results in increased expression of THBD mRNA
CTD
PMID:20713471
NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
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THBS2
thrombospondin 2
multiple interactions
EXP ISO
Methylcholanthrene promotes the reaction [AHR protein binds to THBS2 promoter] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA
CTD
PMID:20348232 PMID:23519560
NCBI chr 6:169,215,785...169,253,846
Ensembl chr 6:169,215,780...169,254,050
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THEM5
thioesterase superfamily member 5
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to THEM5 promoter]
CTD
PMID:20348232
NCBI chr 1:151,847,101...151,853,712
Ensembl chr 1:151,847,101...151,853,712
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TIMP1
TIMP metallopeptidase inhibitor 1
increases expression
EXP
Methylcholanthrene results in increased expression of TIMP1 mRNA
CTD
PMID:22579512
NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789
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TIMP2
TIMP metallopeptidase inhibitor 2
multiple interactions
ISO
[Methylcholanthrene co-treated with Diethylnitrosamine] results in increased expression of TIMP2 mRNA; [Methylcholanthrene co-treated with Diethylnitrosamine] results in increased expression of TIMP2 protein
CTD
PMID:12015029
NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
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TIMP3
TIMP metallopeptidase inhibitor 3
multiple interactions
ISO
[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of TIMP3 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of TIMP3 gene
CTD
PMID:21163286
NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041
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TIPARP
TCDD inducible poly(ADP-ribose) polymerase
increases expression multiple interactions
ISO EXP
Methylcholanthrene results in increased expression of TIPARP mRNA Methylcholanthrene promotes the reaction [AHR protein binds to TIPARP promoter]
CTD
PMID:20348232 PMID:20713471
NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770
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TIPIN
TIMELESS interacting protein
increases expression
ISO
Methylcholanthrene results in increased expression of TIPIN mRNA
CTD
PMID:20713471
NCBI chr15:66,336,191...66,386,717
Ensembl chr15:66,336,191...66,386,746
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TK1
thymidine kinase 1
increases expression
ISO
Methylcholanthrene results in increased expression of TK1 mRNA
CTD
PMID:20713471
NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233
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TM4SF1
transmembrane 4 L six family member 1
increases expression
ISO
Methylcholanthrene results in increased expression of TM4SF1 mRNA
CTD
PMID:20713471
NCBI chr 3:149,369,022...149,377,649
Ensembl chr 3:149,369,022...149,377,692
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TMEM116
transmembrane protein 116
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TMEM116 promoter]
CTD
PMID:20348232
NCBI chr12:111,931,282...112,013,219
Ensembl chr12:111,931,282...112,013,185
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TMEM119
transmembrane protein 119
increases expression
ISO
Methylcholanthrene results in increased expression of TMEM119 mRNA
CTD
PMID:20713471
NCBI chr12:108,589,851...108,598,084
Ensembl chr12:108,589,851...108,598,320
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TMEM184B
transmembrane protein 184B
increases expression
ISO
Methylcholanthrene results in increased expression of TMEM184B mRNA
CTD
PMID:25926378
NCBI chr22:38,216,395...38,273,010
Ensembl chr22:38,219,291...38,273,010
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TMEM30A
transmembrane protein 30A
multiple interactions increases expression
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TMEM30A promoter] Methylcholanthrene results in increased expression of TMEM30A mRNA
CTD
PMID:20348232
NCBI chr 6:75,252,924...75,284,792
Ensembl chr 6:75,252,924...75,284,948
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TMEM45B
transmembrane protein 45B
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TMEM45B promoter]
CTD
PMID:20348232
NCBI chr11:129,815,848...129,860,003
Ensembl chr11:129,815,848...129,860,003
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TMEM97
transmembrane protein 97
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TMEM97 promoter]
CTD
PMID:20348232
NCBI chr17:28,319,200...28,328,685
Ensembl chr17:28,319,200...28,328,685
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TMTC2
transmembrane O-mannosyltransferase targeting cadherins 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TMTC2 promoter]
CTD
PMID:20348232
NCBI chr12:82,686,906...83,134,866
Ensembl chr12:82,686,880...83,134,870
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TNC
tenascin C
decreases expression
ISO
Methylcholanthrene results in decreased expression of TNC mRNA
CTD
PMID:20713471
NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207
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TNF
tumor necrosis factor
multiple interactions increases expression
EXP ISO
[Methylcholanthrene co-treated with TNF protein] results in increased expression of IL6 mRNA Methylcholanthrene results in increased expression of TNF mRNA
CTD
PMID:23273579 PMID:23396138 PMID:35487396
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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TNFRSF21
TNF receptor superfamily member 21
decreases expression
ISO
Methylcholanthrene results in decreased expression of TNFRSF21 mRNA
CTD
PMID:20713471
NCBI chr 6:47,231,532...47,309,905
Ensembl chr 6:47,231,532...47,309,905
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TNFRSF9
TNF receptor superfamily member 9
increases expression
ISO
Methylcholanthrene results in increased expression of TNFRSF9 mRNA
CTD
PMID:20713471
NCBI chr 1:7,915,871...7,940,839
Ensembl chr 1:7,915,871...7,943,165
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TNK2
tyrosine kinase non receptor 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TNK2 promoter]
CTD
PMID:20348232
NCBI chr 3:195,863,364...195,908,551
Ensembl chr 3:195,863,364...195,911,945
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TOP2A
DNA topoisomerase II alpha
increases expression multiple interactions
ISO
Methylcholanthrene results in increased expression of TOP2A mRNA Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of TOP2A mRNA]
CTD
PMID:20713471 PMID:26372666
NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896
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TP53
tumor protein p53
multiple interactions increases expression
ISO
Methylcholanthrene promotes the reaction [TRP53 protein binds to ABCB1B promoter]; Methylcholanthrene promotes the reaction [TRP53 protein binds to FMO3 5' UTR]; Methylcholanthrene results in increased expression of and results in increased activity of TRP53 protein Methylcholanthrene results in increased expression of TP53 mRNA
CTD
PMID:11096091 PMID:20570689 PMID:23273579
NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
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TP53INP2
tumor protein p53 inducible nuclear protein 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of TRP53INP2 mRNA
CTD
PMID:20713471
NCBI chr20:34,704,344...34,713,436
Ensembl chr20:34,704,339...34,713,439
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TPD52
tumor protein D52
increases expression
ISO
Methylcholanthrene results in increased expression of TPD52 mRNA
CTD
PMID:20713471
NCBI chr 8:80,031,082...80,171,564
Ensembl chr 8:80,034,745...80,231,232
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TPST1
tyrosylprotein sulfotransferase 1
increases expression
ISO
Methylcholanthrene results in increased expression of TPST1 mRNA
CTD
PMID:20713471
NCBI chr 7:66,198,790...66,360,443
Ensembl chr 7:66,205,317...66,420,543
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TPX2
TPX2 microtubule nucleation factor
increases expression
ISO
Methylcholanthrene results in increased expression of TPX2 mRNA
CTD
PMID:20713471
NCBI chr20:31,739,290...31,801,800
Ensembl chr20:31,739,271...31,801,805
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TRAF1
TNF receptor associated factor 1
increases expression
ISO
Methylcholanthrene results in increased expression of TRAF1 mRNA
CTD
PMID:29554273
NCBI chr 9:120,902,393...120,929,171
Ensembl chr 9:120,902,393...120,929,173
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TRAPPC9
trafficking protein particle complex subunit 9
decreases expression
EXP
Methylcholanthrene results in decreased expression of TRAPPC9 mRNA
CTD
PMID:22100608
NCBI chr 8:139,727,725...140,458,579
Ensembl chr 8:139,727,725...140,458,579
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TRERF1
transcriptional regulating factor 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TRERF1 promoter]
CTD
PMID:20348232
NCBI chr 6:42,224,931...42,452,224
Ensembl chr 6:42,224,931...42,452,051
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TRIB2
tribbles pseudokinase 2
increases expression
ISO
Methylcholanthrene results in increased expression of TRIB2 mRNA
CTD
PMID:20713471
NCBI chr 2:12,716,936...12,742,734
Ensembl chr 2:12,716,910...12,742,734
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TRIM39
tripartite motif containing 39
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TRIM39 promoter]
CTD
PMID:20348232
NCBI chr 6:30,326,469...30,343,729
Ensembl chr 6:30,326,479...30,343,729
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TRIM55
tripartite motif containing 55
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TRIM55 promoter]
CTD
PMID:20348232
NCBI chr 8:66,113,351...66,175,485
Ensembl chr 8:66,126,896...66,175,485
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TRIM63
tripartite motif containing 63
decreases expression
ISO
Methylcholanthrene results in decreased expression of TRIM63 mRNA
CTD
PMID:20713471
NCBI chr 1:26,051,301...26,067,630
Ensembl chr 1:26,051,301...26,068,436
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TRIM72
tripartite motif containing 72
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TRIM72 promoter]
CTD
PMID:20348232
NCBI chr16:31,214,119...31,231,537
Ensembl chr16:31,214,119...31,231,537
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TRIP13
thyroid hormone receptor interactor 13
increases expression
ISO
Methylcholanthrene results in increased expression of TRIP13 mRNA
CTD
PMID:20713471
NCBI chr 5:892,884...919,348
Ensembl chr 5:892,884...919,357
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TROAP
trophinin associated protein
increases expression
ISO
Methylcholanthrene results in increased expression of TROAP mRNA
CTD
PMID:20713471
NCBI chr12:49,323,255...49,331,731
Ensembl chr12:49,323,236...49,331,731
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TRPV4
transient receptor potential cation channel subfamily V member 4
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TRPV4 promoter]
CTD
PMID:20348232
NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406
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TSLP
thymic stromal lymphopoietin
increases expression
ISO
Methylcholanthrene results in increased expression of TSLP mRNA
CTD
PMID:20713471
NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026
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TSPAN8
tetraspanin 8
increases expression
ISO
Methylcholanthrene results in increased expression of TSPAN8 mRNA
CTD
PMID:20713471
NCBI chr12:71,125,096...71,157,999
Ensembl chr12:71,125,085...71,441,898
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TTC3
tetratricopeptide repeat domain 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to TTC3 promoter]
CTD
PMID:20348232
NCBI chr21:37,073,254...37,203,118
Ensembl chr21:37,073,226...37,203,112
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TTK
TTK protein kinase
increases expression
ISO
Methylcholanthrene results in increased expression of TTK mRNA
CTD
PMID:20713471
NCBI chr 6:80,004,649...80,042,527
Ensembl chr 6:80,003,887...80,042,527
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TUBB4B
tubulin beta 4B class IVb
increases expression
ISO
Methylcholanthrene results in increased expression of TUBB4B mRNA
CTD
PMID:20713471
NCBI chr 9:137,241,287...137,243,707
Ensembl chr 9:137,241,287...137,243,707
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TYMS
thymidylate synthetase
increases expression
EXP
Methylcholanthrene results in increased expression of TYMS mRNA
CTD
PMID:22100608
NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
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UBE2C
ubiquitin conjugating enzyme E2 C
increases expression
ISO
Methylcholanthrene results in increased expression of UBE2C mRNA
CTD
PMID:20713471
NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957
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UBE2E1
ubiquitin conjugating enzyme E2 E1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to UBE2E1 promoter]
CTD
PMID:20348232
NCBI chr 3:23,805,955...23,891,640
Ensembl chr 3:23,805,955...23,891,640
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UBE2T
ubiquitin conjugating enzyme E2 T
increases expression
ISO
Methylcholanthrene results in increased expression of UBE2T mRNA
CTD
PMID:20713471
NCBI chr 1:202,331,657...202,341,936
Ensembl chr 1:202,331,544...202,341,984
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UBTD1
ubiquitin domain containing 1
increases expression
ISO
Methylcholanthrene results in increased expression of UBTD1 mRNA
CTD
PMID:20713471
NCBI chr10:97,498,924...97,571,206
Ensembl chr10:97,498,924...97,571,206
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UCK2
uridine-cytidine kinase 2
decreases expression
ISO
Methylcholanthrene results in decreased expression of UCK2 mRNA
CTD
PMID:25926378
NCBI chr 1:165,827,614...165,911,618
Ensembl chr 1:165,827,614...165,911,618
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UGT1A1
UDP glucuronosyltransferase family 1 member A1
increases expression multiple interactions
EXP ISO
Methylcholanthrene results in increased expression of UGT1A1 mRNA Oxygen deficiency inhibits the reaction [Methylcholanthrene results in increased expression of UGT1A1 mRNA] [Methylcholanthrene results in increased expression of UGT1A1 protein] which results in increased glucuronidation of 3,6-dihydroxychrysene; [Methylcholanthrene results in increased expression of UGT1A1 protein] which results in increased glucuronidation of 6-hydroxychrysene Methylcholanthrene results in increased expression of UGT1A1 mRNA; Methylcholanthrene results in increased expression of UGT1A1 protein
CTD
PMID:1435739 PMID:18203689 PMID:19118567 PMID:33811995
NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
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UGT1A10
UDP glucuronosyltransferase family 1 member A10
increases expression
EXP ISO
Methylcholanthrene results in increased expression of UGT1A10 mRNA
CTD
PMID:19118567 PMID:28601433 PMID:29554273
NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300
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UGT1A3
UDP glucuronosyltransferase family 1 member A3
increases expression
EXP
Methylcholanthrene results in increased expression of UGT1A2 mRNA; Methylcholanthrene results in increased expression of UGT1A3 mRNA
CTD
PMID:19118567 PMID:28601433
NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300
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UGT1A4
UDP glucuronosyltransferase family 1 member A4
increases expression
EXP
Methylcholanthrene results in increased expression of UGT1A4 mRNA
CTD
PMID:19118567
NCBI chr 2:233,718,736...233,773,300
Ensembl chr 2:233,718,736...233,773,300
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UGT1A5
UDP glucuronosyltransferase family 1 member A5
increases expression
EXP
Methylcholanthrene results in increased expression of UGT1A5 mRNA
CTD
PMID:19118567 PMID:28601433
NCBI chr 2:233,712,907...233,773,300
Ensembl chr 2:233,712,907...233,773,300
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UGT1A6
UDP glucuronosyltransferase family 1 member A6
increases expression increases activity multiple interactions
EXP ISO
Methylcholanthrene results in increased expression of UGT1A6 mRNA Methylcholanthrene results in increased activity of UGT1A6 protein [Methylcholanthrene results in increased activity of UGT1A6 protein] which affects the metabolism of Benzene; Methylcholanthrene promotes the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol]; UGT1A6 protein affects the reaction [Methylcholanthrene results in increased abundance of Ascorbic Acid] [Methylcholanthrene co-treated with Oxygen deficiency] results in decreased expression of UGT1A6 mRNA; Oxygen deficiency inhibits the reaction [Methylcholanthrene results in increased expression of UGT1A6 mRNA]
CTD
PMID:1981726 PMID:8263600 PMID:11328961 PMID:19023562 PMID:19118567 PMID:28601433 PMID:33811995 More...
NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300
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UGT1A7
UDP glucuronosyltransferase family 1 member A7
increases expression
EXP
Methylcholanthrene results in increased expression of UGT1A7 mRNA
CTD
PMID:19118567 PMID:28601433
NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300
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UGT1A8
UDP glucuronosyltransferase family 1 member A8
increases expression
EXP
Methylcholanthrene results in increased expression of UGT1A8 mRNA
CTD
PMID:19118567 PMID:28601433
NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300
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UGT1A9
UDP glucuronosyltransferase family 1 member A9
increases expression
EXP
Methylcholanthrene results in increased expression of UGT1A9 mRNA
CTD
PMID:19118567
NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300
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UGT2B7
UDP glucuronosyltransferase family 2 member B7
increases expression
EXP
Methylcholanthrene results in increased expression of UGT2B7 mRNA
CTD
PMID:19118567
NCBI chr 4:69,051,375...69,112,987
Ensembl chr 4:69,051,363...69,112,987
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UMODL1
uromodulin like 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to UMODL1 promoter]
CTD
PMID:20348232
NCBI chr21:42,062,877...42,142,996
Ensembl chr21:42,062,959...42,143,453
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UPP1
uridine phosphorylase 1
increases expression
ISO
Methylcholanthrene results in increased expression of UPP1 mRNA
CTD
PMID:20713471
NCBI chr 7:48,088,704...48,108,736
Ensembl chr 7:48,088,628...48,108,736
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USP17L5
ubiquitin specific peptidase 17 like family member 5
affects expression
ISO
Methylcholanthrene affects the expression of USP17LA mRNA
CTD
PMID:20713471
NCBI chr 4:9,339,403...9,340,995
Ensembl chr 4:9,339,403...9,340,995
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USP18
ubiquitin specific peptidase 18
decreases expression increases expression
ISO
Methylcholanthrene results in decreased expression of USP18 mRNA Methylcholanthrene results in increased expression of USP18 mRNA
CTD
PMID:20713471 PMID:29554273
NCBI chr22:18,150,170...18,177,397
Ensembl chr22:18,150,118...18,177,397
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USP9X
ubiquitin specific peptidase 9 X-linked
increases expression
ISO
Methylcholanthrene results in increased expression of USP9X mRNA
CTD
PMID:25926378
NCBI chr X:41,085,445...41,236,579
Ensembl chr X:41,085,445...41,236,579
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VAV3
vav guanine nucleotide exchange factor 3
increases expression
ISO
Methylcholanthrene results in increased expression of VAV3 mRNA
CTD
PMID:20713471
NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180
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VCAM1
vascular cell adhesion molecule 1
affects expression
ISO
Methylcholanthrene affects the expression of VCAM1 mRNA
CTD
PMID:35487396
NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
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VEGFA
vascular endothelial growth factor A
increases expression
ISO
Methylcholanthrene results in increased expression of VEGFA mRNA
CTD
PMID:15585370
NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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VEZT
vezatin, adherens junctions transmembrane protein
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to VEZT promoter]
CTD
PMID:20348232
NCBI chr12:95,217,807...95,302,799
Ensembl chr12:95,217,746...95,302,799
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VIPR1
vasoactive intestinal peptide receptor 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to VIPR1 promoter]
CTD
PMID:20348232
NCBI chr 3:42,489,299...42,537,568
Ensembl chr 3:42,489,299...42,537,573
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VIT
vitrin
multiple interactions
ISO
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of VIT mRNA
CTD
PMID:23519560
NCBI chr 2:36,696,707...36,814,794
Ensembl chr 2:36,696,690...36,814,794
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VSTM1
V-set and transmembrane domain containing 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to VSTM1 promoter]
CTD
PMID:20348232
NCBI chr19:54,040,825...54,063,897
Ensembl chr19:54,040,825...54,063,953
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VWCE
von Willebrand factor C and EGF domains
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to VWCE promoter]
CTD
PMID:20348232
NCBI chr11:61,258,286...61,295,316
Ensembl chr11:61,258,286...61,295,316
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VWF
von Willebrand factor
multiple interactions
ISO
[Methylcholanthrene co-treated with Nanotubes, Carbon] affects the expression of VWF mRNA
CTD
PMID:25926378
NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
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WBP1L
WW domain binding protein 1 like
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to WBP1L promoter]
CTD
PMID:20348232
NCBI chr10:102,743,948...102,816,262
Ensembl chr10:102,743,948...102,834,516
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WDFY4
WDFY family member 4
increases expression
ISO
Methylcholanthrene results in increased expression of WDFY4 mRNA
CTD
PMID:25926378
NCBI chr10:48,684,873...48,982,956
Ensembl chr10:48,684,873...48,982,956
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WDR26
WD repeat domain 26
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to WDR26 promoter]
CTD
PMID:20348232
NCBI chr 1:224,385,146...224,434,797
Ensembl chr 1:224,385,146...224,437,033
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WEE1
WEE1 G2 checkpoint kinase
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to WEE1 promoter]
CTD
PMID:20348232
NCBI chr11:9,573,670...9,589,985
Ensembl chr11:9,573,670...9,593,457
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WWOX
WW domain containing oxidoreductase
decreases expression
ISO
Methylcholanthrene results in decreased expression of WWOX mRNA
CTD
PMID:20713471
NCBI chr16:78,099,654...79,212,667
Ensembl chr16:78,099,400...79,212,667
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WWTR1
WW domain containing transcription regulator 1
increases expression
ISO
Methylcholanthrene results in increased expression of WWTR1 mRNA
CTD
PMID:20713471
NCBI chr 3:149,517,235...149,724,788
Ensembl chr 3:149,517,235...149,736,714
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XDH
xanthine dehydrogenase
multiple interactions increases expression increases activity
ISO
AHR protein promotes the reaction [Methylcholanthrene results in increased activity of XDH protein] Methylcholanthrene results in increased expression of XDH mRNA
CTD
PMID:11243847 PMID:20713471 PMID:23273579 PMID:29554273
NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742
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ZBTB4
zinc finger and BTB domain containing 4
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ZBTB4 promoter]
CTD
PMID:20348232
NCBI chr17:7,459,378...7,484,249
Ensembl chr17:7,459,366...7,484,263
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ZC3H8
zinc finger CCCH-type containing 8
decreases expression
ISO
Methylcholanthrene results in decreased expression of ZC3H8 mRNA
CTD
PMID:20713471
NCBI chr 2:112,211,529...112,255,042
Ensembl chr 2:112,211,529...112,255,136
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ZCCHC2
zinc finger CCHC-type containing 2
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ZCCHC2 promoter]
CTD
PMID:20348232
NCBI chr18:62,523,025...62,586,729
Ensembl chr18:62,523,025...62,587,709
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ZCCHC9
zinc finger CCHC-type containing 9
decreases expression
ISO
Methylcholanthrene results in decreased expression of ZCCHC9 mRNA
CTD
PMID:25926378
NCBI chr 5:81,301,587...81,313,297
Ensembl chr 5:81,301,587...81,313,297
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ZDHHC2
zinc finger DHHC-type palmitoyltransferase 2
increases expression
ISO
Methylcholanthrene results in increased expression of ZDHHC2 mRNA
CTD
PMID:20713471
NCBI chr 8:17,156,482...17,224,799
Ensembl chr 8:17,156,482...17,224,799
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ZFP37
ZFP37 zinc finger protein
decreases expression
ISO
Methylcholanthrene results in decreased expression of ZFP37 mRNA
CTD
PMID:35487396
NCBI chr 9:113,038,377...113,056,724
Ensembl chr 9:113,038,377...113,056,759
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ZMAT3
zinc finger matrin-type 3
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ZMAT3 promoter]
CTD
PMID:20348232
NCBI chr 3:179,017,223...179,072,513
Ensembl chr 3:178,960,121...179,072,215
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ZMIZ1
zinc finger MIZ-type containing 1
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ZMIZ1 promoter]
CTD
PMID:20348232
NCBI chr10:79,068,966...79,316,519
Ensembl chr10:79,068,966...79,316,519
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ZNF281
zinc finger protein 281
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ZNF281 promoter]
CTD
PMID:20348232
NCBI chr 1:200,404,951...200,410,036
Ensembl chr 1:200,404,940...200,410,056
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ZNF467
zinc finger protein 467
increases expression
ISO
Methylcholanthrene results in increased expression of ZFP467 mRNA
CTD
PMID:20713471
NCBI chr 7:149,764,182...149,776,530
Ensembl chr 7:149,764,182...149,773,588
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ZNF521
zinc finger protein 521
decreases expression
ISO
Methylcholanthrene results in decreased expression of ZFP521 mRNA
CTD
PMID:20713471
NCBI chr18:25,061,924...25,352,166
Ensembl chr18:25,061,924...25,352,190
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ZNF552
zinc finger protein 552
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ZNF552 promoter]
CTD
PMID:20348232
NCBI chr19:57,807,082...57,814,913
Ensembl chr19:57,803,841...57,814,913
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ZNF587
zinc finger protein 587
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ZNF587 promoter]
CTD
PMID:20348232
NCBI chr19:57,849,859...57,865,117
Ensembl chr19:57,849,859...57,865,117
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ZNF695
zinc finger protein 695
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ZNF695 promoter]
CTD
PMID:20348232
NCBI chr 1:246,945,546...247,008,057
Ensembl chr 1:246,945,547...247,008,093
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ZNF710
zinc finger protein 710
multiple interactions
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to ZNF710 promoter]
CTD
PMID:20348232
NCBI chr15:89,998,307...90,082,191
Ensembl chr15:90,001,324...90,082,206
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ZWILCH
zwilch kinetochore protein
increases expression
ISO
Methylcholanthrene results in increased expression of ZWILCH mRNA
CTD
PMID:20713471
NCBI chr15:66,505,326...66,550,130
Ensembl chr15:66,504,959...66,550,130
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