CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 2,6-dimethylnaphthalene
Accession: CHEBI:34251
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Definition: A dimethylnaphthalene carrying methyl groups at positions 2 and 6.
Synonyms: related_synonym: 2,6-DMN; Formula=C12H12; InChI=1S/C12H12/c1-9-3-5-12-8-10(2)4-6-11(12)7-9/h3-8H,1-2H3; InChIKey=YGYNBBAUIYTWBF-UHFFFAOYSA-N; SMILES=Cc1ccc2cc(C)ccc2c1
xref: Beilstein:1903544; CAS:581-42-0; HMDB:HMDB0059764; KEGG:C14330
xref_mesh: MESH:C028519
xref: PMID:20526527; PMID:22324881; Patent:EP1852409; Reaxys:1903544; Wikipedia:2\,6-Dimethylnaphthalene
G
Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
2,6-dimethylnaphthalene binds to and results in increased activity of AHR protein
CTD
PMID:27633901
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
decreases activity
ISO
2,6-dimethylnaphthalene results in decreased activity of CYP1A2 protein
CTD
PMID:15916432
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases oxidation
ISO
CYP2E1 protein results in increased oxidation of 2,6-dimethylnaphthalene
CTD
PMID:17156750
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
Esr1
estrogen receptor 1
multiple interactions
ISO
2,6-dimethylnaphthalene binds to and results in increased activity of ESR1 protein
CTD
PMID:27633901
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Esr2
estrogen receptor 2
multiple interactions
ISO
2,6-dimethylnaphthalene binds to and results in increased activity of ESR2 protein
CTD
PMID:27633901
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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