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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:anthraflavic acid
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Accession:CHEBI:34250 term browser browse the term
Definition:A dihydroxyanthraquinone that is anthracene substituted by hydroxy groups at C-3 and C-7 and oxo groups at C-9 and C-10.
Synonyms:exact_synonym: 2,6-dihydroxyanthracene-9,10-dione
 related_synonym: 2,6-Dihydroxyanthraquinone;   2,6-dihydroxy-9,10-anthracenedione;   2,6-dihydroxy-9,10-anthraquinone;   2,6-dihydroxyanthra-9,10-quinone;   Az-F;   Formula=C14H8O4;   InChI=1S/C14H8O4/c15-7-1-3-9-11(5-7)14(18)10-4-2-8(16)6-12(10)13(9)17/h1-6,15-16H;   InChIKey=APAJFZPFBHMFQR-UHFFFAOYSA-N;   SMILES=Oc1ccc2C(=O)c3cc(O)ccc3C(=O)c2c1;   anthraflavin
 xref: Beilstein:2054127;   CAS:84-60-6;   Gmelin:29519;   KEGG:C14267
 xref_mesh: MESH:C034889
 xref: PMID:14500876;   PMID:3128399;   PMID:3209131;   PMID:3282161;   PMID:3492267;   PMID:3689794;   PMID:3802081;   PMID:3918802;   PMID:8304922;   PMID:863051;   Reaxys:2054127


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anthraflavic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 2,6-dihydroxyanthraquinone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:19269596 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Alb albumin affects binding ISO 2,6-dihydroxyanthraquinone binds to ALB protein CTD PMID:16404478 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 2,6-dihydroxyanthraquinone results in increased expression of CYP1A1 mRNA CTD PMID:11502733 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 2,6-dihydroxyanthraquinone results in increased expression of CYP1B1 mRNA CTD PMID:11502733 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 2,6-dihydroxyanthraquinone CTD PMID:12756209 PMID:14557274 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 2,6-dihydroxyanthraquinone CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465 JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        antimutagen 79
          anthraflavic acid 6
Path 2
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  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      ketone 16924
                                        cyclic ketone 15393
                                          quinone 8376
                                            acenoquinone 7507
                                              anthraquinone 476
                                                hydroxyanthraquinones 466
                                                  dihydroxyanthraquinone 322
                                                    anthraflavic acid 6
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