Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:carmustine
go back to main search page
Accession:CHEBI:3423 term browser browse the term
Definition:A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Synonyms:exact_synonym: 1,3-bis(2-chloroethyl)-1-nitrosourea
 related_synonym: BCNU;   Bicnu (TN);   Bischloroethyl nitrosourea;   Formula=C5H9Cl2N3O2;   Gliadel;   InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11);   InChIKey=DLGOEMSEDOSKAD-UHFFFAOYSA-N;   N,N'-Bis(2-chloroethyl)-N-nitrosourea;   SMILES=ClCCNC(=O)N(CCCl)N=O;   carmustina;   carmustinum
 xref: CAS:154-93-8;   DrugBank:DB00262;   Drug_Central:512;   KEGG:D00254
 xref_mesh: MESH:D002330
 xref: Wikipedia:Carmustine


show annotations for term's descendants           Sort by:
 
carmustine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
ISO Carmustine results in increased expression of ABCB1 protein
[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Carmustine
CTD PMID:11792417 PMID:15239124 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects response to substance ISO ABCC2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects response to substance ISO ABCG5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Acer2 alkaline ceramidase 2 increases expression EXP Carmustine results in increased expression of ACER2 mRNA CTD PMID:16005536 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
JBrowse link
G Acp3 acid phosphatase 3 decreases expression EXP Carmustine results in decreased expression of ACP3 mRNA CTD PMID:16005536 NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression ISO Carmustine results in decreased expression of ACTC1 mRNA CTD PMID:15980968 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO Carmustine results in decreased expression of ACTG2 mRNA CTD PMID:15980968 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Actn1 actinin, alpha 1 decreases expression ISO Carmustine results in decreased expression of ACTN1 mRNA CTD PMID:15980968 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 decreases expression ISO Carmustine results in decreased expression of ADAM15 mRNA CTD PMID:15980968 NCBI chr 2:174,754,631...174,765,136
Ensembl chr 2:174,754,633...174,765,113
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 decreases expression ISO Carmustine results in decreased expression of ADAMTS4 mRNA CTD PMID:15980968 NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 decreases expression ISO Carmustine results in decreased expression of ADCYAP1 mRNA CTD PMID:15980968 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Adra1b adrenoceptor alpha 1B decreases expression ISO Carmustine results in decreased expression of ADRA1B mRNA CTD PMID:15980968 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Agr3 anterior gradient 3, protein disulphide isomerase family member affects response to substance ISO AGR3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:52,643,391...52,666,638
Ensembl chr 6:52,643,391...52,666,638
JBrowse link
G Agt angiotensinogen decreases response to substance ISO AGT protein mutant form results in decreased susceptibility to Carmustine; AGT protein results in decreased susceptibility to Carmustine CTD PMID:11034089 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B affects response to substance ISO AKR1B1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
affects response to substance
EXP
ISO
Carmustine results in decreased phosphorylation of AKT1 protein
LCN2 protein promotes the reaction [Carmustine results in decreased phosphorylation of AKT1 protein]
AKT1 protein affects the susceptibility to Carmustine
CTD PMID:18430789 PMID:19860839 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression ISO Carmustine results in decreased expression of AKT2 mRNA CTD PMID:15980968 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Alad aminolevulinate dehydratase decreases expression
multiple interactions
ISO Carmustine results in decreased expression of ALAD mRNA
[Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein
CTD PMID:15980968 PMID:19162187 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression EXP Carmustine results in decreased expression of ALAS2 mRNA CTD PMID:16005536 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 affects response to substance ISO ALDH1A3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type affects response to substance
decreases expression
ISO
EXP
ALOX12 protein affects the susceptibility to Carmustine
Carmustine results in decreased expression of ALOX12 mRNA
CTD PMID:16005536 PMID:19373248 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B decreases expression ISO Carmustine results in decreased expression of ALOX15B mRNA CTD PMID:15980968 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812
JBrowse link
G Amh anti-Mullerian hormone decreases expression ISO Carmustine results in decreased expression of AMH mRNA CTD PMID:15980968 NCBI chr 7:8,906,776...8,909,184
Ensembl chr 7:8,906,836...8,909,282
JBrowse link
G Ank2 ankyrin 2 affects response to substance ISO ANK2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Ankrd1 ankyrin repeat domain 1 affects response to substance ISO ANKRD1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 affects response to substance ISO AP1S2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr  X:30,572,746...30,598,961
Ensembl chr  X:30,572,751...30,597,262
JBrowse link
G Apc APC regulator of WNT signaling pathway affects response to substance ISO APC mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 decreases expression ISO Carmustine results in decreased expression of APC2 mRNA CTD PMID:15980968 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance
decreases response to substance
ISO APEX1 protein mutant form results in increased susceptibility to Carmustine
APEX1 protein results in decreased susceptibility to Carmustine
CTD PMID:12231548 PMID:16243814 PMID:17259346 PMID:19470598 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Aplnr apelin receptor decreases expression ISO Carmustine results in decreased expression of APLNR mRNA CTD PMID:15980968 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Aqp8 aquaporin 8 decreases expression ISO Carmustine results in decreased expression of AQP8 mRNA CTD PMID:15980968 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
JBrowse link
G Arf1 ADP-ribosylation factor 1 affects response to substance ISO ARF1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:43,997,983...44,014,543
Ensembl chr10:43,997,986...44,014,434
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression EXP Carmustine results in decreased expression of ARNTL mRNA CTD PMID:16005536 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 decreases expression ISO Carmustine results in decreased expression of ARPC2 mRNA CTD PMID:15980968 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
JBrowse link
G Arrdc2 arrestin domain containing 2 affects response to substance ISO ARRDC2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029
JBrowse link
G Artn artemin decreases expression ISO Carmustine results in decreased expression of ARTN mRNA CTD PMID:15980968 NCBI chr 5:131,458,596...131,470,193
Ensembl chr 5:131,464,756...131,468,025
JBrowse link
G Asmtl acetylserotonin O-methyltransferase-like decreases expression ISO Carmustine results in decreased expression of ASMTL mRNA CTD PMID:15980968 NCBI chr12:16,315,335...16,321,607
Ensembl chr12:16,315,414...16,318,080
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 decreases expression ISO Carmustine results in decreased expression of ATP1A3 mRNA CTD PMID:15980968 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp4b ATPase H+/K+ transporting subunit beta decreases expression ISO Carmustine results in decreased expression of ATP4B mRNA CTD PMID:15980968 NCBI chr16:76,144,150...76,153,063
Ensembl chr16:76,144,150...76,153,063
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta decreases expression ISO Carmustine results in decreased expression of ATP5F1D mRNA CTD PMID:15980968 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C decreases expression ISO Carmustine results in decreased expression of ATP6V0C mRNA CTD PMID:15980968 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions ISO ATR protein affects the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein] CTD PMID:19261750 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Atxn2l ataxin 2-like decreases expression ISO Carmustine results in decreased expression of ATXN2L mRNA CTD PMID:15980968 NCBI chr 1:181,078,293...181,090,079
Ensembl chr 1:181,078,288...181,089,686
JBrowse link
G Avpr1a arginine vasopressin receptor 1A increases expression ISO Carmustine results in increased expression of AVPR1A mRNA CTD PMID:15980968 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G B4galt5 beta-1,4-galactosyltransferase 5 decreases expression ISO Carmustine results in decreased expression of B4GALT5 mRNA CTD PMID:15980968 NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 decreases expression ISO Carmustine results in decreased expression of BAIAP2 mRNA CTD PMID:15980968 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
JBrowse link
G Baiap3 BAI1-associated protein 3 decreases expression ISO Carmustine results in decreased expression of BAIAP3 mRNA CTD PMID:15980968 NCBI chr10:14,260,269...14,273,019
Ensembl chr10:14,260,269...14,273,019
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Carmustine results in increased expression of BAX protein CTD PMID:20920327 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl10 BCL10, immune signaling adaptor increases expression ISO Carmustine results in increased expression of BCL10 mRNA CTD PMID:15980968 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
affects response to substance
decreases expression
ISO [Fenretinide co-treated with Carmustine] results in decreased expression of BCL2 protein
BCL2 protein affects the susceptibility to Carmustine
Carmustine results in decreased expression of BCL2 protein
CTD PMID:15332326 PMID:16187019 PMID:18430789 PMID:20920327 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 affects response to substance
decreases expression
multiple interactions
ISO
EXP
BCL2L1 protein affects the susceptibility to Carmustine
Carmustine results in decreased expression of BCL2L1 protein
[Fenretinide co-treated with Carmustine] results in decreased expression of BCL2L1 protein
Carmustine results in decreased expression of BCL2L1 mRNA; Carmustine results in decreased expression of BCL2L1 protein
CTD PMID:15332326 PMID:16187019 PMID:19860839 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Becn1 beclin 1 decreases expression ISO Carmustine results in decreased expression of BECN1 mRNA CTD PMID:15980968 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bicd1 BICD cargo adaptor 1 decreases expression ISO Carmustine results in decreased expression of BICD1 mRNA CTD PMID:15980968 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase decreases expression ISO Carmustine results in decreased expression of BLK mRNA CTD PMID:15980968 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
JBrowse link
G Bmp5 bone morphogenetic protein 5 affects response to substance ISO BMP5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925
JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression ISO Carmustine results in decreased expression of BMP7 mRNA CTD PMID:15980968 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Brf1 BRF1, RNA polymerase III transcription initiation factor subunit decreases expression ISO Carmustine results in decreased expression of BRF1 mRNA CTD PMID:15980968 NCBI chr 6:132,034,380...132,081,296
Ensembl chr 6:132,037,272...132,081,278
JBrowse link
G Ca6 carbonic anhydrase 6 decreases expression ISO Carmustine results in decreased expression of CA6 mRNA CTD PMID:15980968 NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644
JBrowse link
G Cadm1 cell adhesion molecule 1 affects response to substance ISO CADM1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Calb2 calbindin 2 decreases expression ISO Carmustine results in decreased expression of CALB2 mRNA CTD PMID:15980968 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression
EXP
ISO
Carmustine results in increased activity of CASP3 protein
[Carmustine co-treated with 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid] results in increased activity of CASP3 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of CASP3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; [LCN2 protein co-treated with Carmustine] results in increased cleavage of and results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; Carmustine results in increased activity of and results in increased cleavage of CASP3 protein; pyrazolanthrone inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; Zinc Sulfate inhibits the reaction [Carmustine results in increased activity of CASP3 protein]
Carmustine results in increased expression of CASP3 protein
CTD PMID:18590702 PMID:19860839 PMID:20046642 PMID:20920327 PMID:21600974 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP Carmustine results in decreased activity of CAT protein
Acetylcysteine inhibits the reaction [Carmustine results in decreased activity of CAT protein]
CTD PMID:20332008 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects activity
affects response to substance
increases expression
decreases expression
ISO Carmustine affects the activity of CCL2 protein
CCL2 mRNA affects the susceptibility to Carmustine
Carmustine results in increased expression of CCL2 mRNA
Carmustine results in decreased expression of CCL2 protein
CTD PMID:15980968 PMID:16365179 PMID:17522861 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccn4 cellular communication network factor 4 affects response to substance ISO CCN4 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
JBrowse link
G Ccnd1 cyclin D1 affects response to substance ISO CCND1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 increases expression EXP Carmustine results in increased expression of CCNE1 mRNA CTD PMID:16005536 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cd151 CD151 molecule (Raph blood group) decreases expression ISO Carmustine results in decreased expression of CD151 mRNA CTD PMID:15980968 NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:196,565,181...196,568,753
JBrowse link
G Cd44 CD44 molecule (Indian blood group) affects response to substance ISO CD44 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd68 Cd68 molecule decreases expression ISO Carmustine results in decreased expression of CD68 mRNA CTD PMID:15980968 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cd79a CD79a molecule decreases expression ISO Carmustine results in decreased expression of CD79A mRNA CTD PMID:15980968 NCBI chr 1:80,493,520...80,497,936
Ensembl chr 1:80,493,581...80,497,935
JBrowse link
G Cd80 Cd80 molecule increases expression ISO Carmustine results in increased expression of CD80 mRNA CTD PMID:15980968 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cdc25b cell division cycle 25B decreases expression EXP Carmustine results in decreased expression of CDC25B mRNA CTD PMID:16005536 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdh13 cadherin 13 affects response to substance ISO CDH13 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
JBrowse link
G Cdk8 cyclin-dependent kinase 8 decreases expression ISO Carmustine results in decreased expression of CDK8 mRNA CTD PMID:15980968 NCBI chr12:8,737,198...8,805,026 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [Carmustine co-treated with O(6)-benzylguanine] results in increased expression of CDKN1A protein; MDM4 protein promotes the reaction [Carmustine results in increased expression of CDKN1A protein] CTD PMID:15735757 PMID:16193384 PMID:18632648 PMID:20472715 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C affects response to substance ISO CDKN1C mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases response to substance ISO CDKN2A protein results in increased susceptibility to Carmustine CTD PMID:16786135 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Carmustine results in decreased expression of CDKN3 mRNA CTD PMID:16005536 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cdx4 caudal type homeo box 4 decreases expression ISO Carmustine results in decreased expression of CDX4 mRNA CTD PMID:15980968 NCBI chr  X:68,326,874...68,335,461
Ensembl chr  X:68,326,874...68,335,461
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO Carmustine results in decreased expression of CEBPB mRNA CTD PMID:15980968 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP Carmustine results in increased expression of CGREF1 mRNA CTD PMID:16005536 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 affects response to substance ISO CHD2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:127,188,146...127,317,041
Ensembl chr 1:127,190,059...127,300,502
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO ATR protein affects the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]; Caffeine inhibits the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]; Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein; O(6)-benzylguanine promotes the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]; wortmannin inhibits the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein] CTD PMID:19261750 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 decreases expression ISO Carmustine results in decreased expression of CHRM4 mRNA CTD PMID:15980968 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit decreases expression ISO Carmustine results in decreased expression of CHRNB3 mRNA CTD PMID:15980968 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit decreases expression ISO Carmustine results in decreased expression of CHRNG mRNA CTD PMID:15980968 NCBI chr 9:87,878,085...87,884,193 JBrowse link
G Ckm creatine kinase, M-type decreases expression ISO Carmustine results in decreased expression of CKM mRNA CTD PMID:15980968 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Clic1 chloride intracellular channel 1 multiple interactions
decreases response to substance
ISO [4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLIC1 protein] which results in increased susceptibility to Carmustine
CLIC1 protein results in decreased susceptibility to Carmustine
CTD PMID:18590702 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
JBrowse link
G Cntnap1 contactin associated protein 1 increases expression ISO Carmustine results in increased expression of CNTNAP1 mRNA CTD PMID:15980968 NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
JBrowse link
G Col1a1 collagen type I alpha 1 chain affects response to substance ISO COL1A1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col5a3 collagen type V alpha 3 chain decreases expression EXP Carmustine results in decreased expression of COL5A3 mRNA CTD PMID:16005536 NCBI chr 8:19,304,564...19,349,809
Ensembl chr 8:19,304,571...19,349,853
JBrowse link
G Col9a1 collagen type IX alpha 1 chain decreases expression ISO Carmustine results in decreased expression of COL9A1 mRNA CTD PMID:15980968 NCBI chr 9:26,585,034...26,668,222
Ensembl chr 9:26,585,034...26,668,213
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression ISO Carmustine results in decreased expression of COX6A2 mRNA CTD PMID:15980968 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 decreases expression ISO Carmustine results in decreased expression of CRABP1 mRNA CTD PMID:15980968 NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360
JBrowse link
G Crat carnitine O-acetyltransferase decreases expression ISO Carmustine results in decreased expression of CRAT mRNA CTD PMID:15980968 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
G Crybb1 crystallin, beta B1 decreases expression ISO Carmustine results in decreased expression of CRYBB1 mRNA CTD PMID:15980968 NCBI chr12:44,369,734...44,383,344
Ensembl chr12:44,369,735...44,383,344
JBrowse link
G Csf2 colony stimulating factor 2 affects response to substance ISO CSF2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 affects response to substance ISO CSGALNACT1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 affects response to substance ISO CSRP3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Cst5 cystatin D decreases expression ISO Carmustine results in decreased expression of CST5 mRNA CTD PMID:15980968 NCBI chr 3:137,573,194...137,577,754
Ensembl chr 3:137,573,194...137,577,754
JBrowse link
G Ctf1 cardiotrophin 1 decreases expression ISO Carmustine results in decreased expression of CTF1 mRNA CTD PMID:15980968 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
JBrowse link
G Ctnnal1 catenin alpha-like 1 increases expression ISO Carmustine results in increased expression of CTNNAL1 mRNA CTD PMID:15980968 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431
JBrowse link
G Ctsl cathepsin L increases expression EXP Carmustine results in increased expression of CTSL mRNA CTD PMID:16005536 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cux2 cut-like homeobox 2 affects expression EXP Carmustine affects the expression of CUX2 mRNA CTD PMID:19174181 NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 affects response to substance ISO CXCL1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 affects response to substance ISO CXCL2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 affects response to substance ISO CXCL1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO Carmustine results in decreased expression of CYP19A1 mRNA CTD PMID:15980968 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin] CTD PMID:16087946 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO CYP3A5 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin] CTD PMID:16087946 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyth1 cytohesin 1 increases expression ISO Carmustine results in increased expression of CYTH1 mRNA CTD PMID:15980968 NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760
JBrowse link
G Def6 DEF6 guanine nucleotide exchange factor affects response to substance ISO DEF6 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr20:6,268,614...6,290,030
Ensembl chr20:6,268,601...6,289,961
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 affects response to substance ISO DHRS3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dhx16 DEAH-box helicase 16 decreases expression ISO Carmustine results in decreased expression of DHX16 mRNA CTD PMID:15980968 NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
JBrowse link
G Dhx37 DEAH-box helicase 37 affects response to substance ISO DHX37 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:31,194,782...31,214,890
Ensembl chr12:31,194,859...31,216,802
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases response to substance ISO DKK1 protein results in increased susceptibility to Carmustine CTD PMID:20920327 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dmrtc2 DMRT-like family C2 affects response to substance ISO DMRTC2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:80,466,259...80,473,883
Ensembl chr 1:80,466,132...80,473,531
JBrowse link
G Dna2 DNA replication helicase/nuclease 2 affects response to substance ISO DNA2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr20:25,661,652...25,690,598 JBrowse link
G Dnase1l2 deoxyribonuclease 1 like 2 decreases expression ISO Carmustine results in decreased expression of DNASE1L2 mRNA CTD PMID:15980968 NCBI chr10:13,471,850...13,473,447
Ensembl chr10:13,471,479...13,473,763
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 decreases expression ISO Carmustine results in decreased expression of DVL1 mRNA CTD PMID:15980968 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664
JBrowse link
G Dyrk1b dual specificity tyrosine phosphorylation regulated kinase 1B affects response to substance ISO DYRK1B mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:83,479,139...83,497,011
Ensembl chr 1:83,479,147...83,487,169
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Carmustine results in increased expression of E2F1 protein CTD PMID:18632648 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Ecm2 extracellular matrix protein 2 increases expression ISO Carmustine results in increased expression of ECM2 mRNA CTD PMID:15980968 NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516
JBrowse link
G Ednra endothelin receptor type A affects response to substance ISO EDNRA mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma increases expression ISO Carmustine results in increased expression of EEF1G mRNA CTD PMID:15980968 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha increases expression ISO Carmustine results in increased expression of EIF2B1 mRNA CTD PMID:15980968 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects response to substance ISO EIF4A2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif6 eukaryotic translation initiation factor 6 decreases expression ISO Carmustine results in decreased expression of EIF6 mRNA CTD PMID:15980968 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
JBrowse link
G Elmo1 engulfment and cell motility 1 affects response to substance ISO ELMO1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr17:44,286,495...44,822,788
Ensembl chr17:44,286,485...44,822,788
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression EXP Carmustine results in increased expression of ENC1 mRNA CTD PMID:16005536 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Carmustine results in decreased expression of EPHX1 mRNA CTD PMID:15980968 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Espn espin increases expression EXP Carmustine results in increased expression of ESPN mRNA CTD PMID:16005536 NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256
JBrowse link
G Esrra estrogen related receptor, alpha increases expression ISO Carmustine results in increased expression of ESRRA mRNA CTD PMID:15980968 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
JBrowse link
G Etv1 ETS variant transcription factor 1 affects response to substance
affects expression
ISO
EXP
ETV1 mRNA affects the susceptibility to Carmustine
Carmustine affects the expression of ETV1 mRNA
CTD PMID:16365179 PMID:19174181 NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775
JBrowse link
G Extl1 exostosin-like glycosyltransferase 1 affects response to substance ISO EXTL1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO Carmustine results in decreased expression of EZH2 mRNA CTD PMID:15980968 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G F3 coagulation factor III, tissue factor increases expression EXP Carmustine results in increased expression of F3 mRNA CTD PMID:16005536 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fancc FA complementation group C affects response to substance ISO FANCC mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376
JBrowse link
G Fancd2 FA complementation group D2 increases ubiquitination
affects localization
ISO Carmustine results in increased ubiquitination of FANCD2 protein
Carmustine affects the localization of FANCD2 protein
CTD PMID:17221219 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
JBrowse link
G Fbln5 fibulin 5 decreases expression EXP Carmustine results in decreased expression of FBLN5 mRNA CTD PMID:16005536 NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755
JBrowse link
G Fbn1 fibrillin 1 decreases expression ISO Carmustine results in decreased expression of FBN1 mRNA CTD PMID:15980968 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbxo32 F-box protein 32 affects response to substance ISO FBXO32 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fech ferrochelatase multiple interactions ISO [MGMT protein mutant form co-treated with FECH protein] results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine] CTD PMID:12950064 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases response to substance ISO FGF2 protein results in decreased susceptibility to Carmustine CTD PMID:20221717 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fhl2 four and a half LIM domains 2 affects response to substance ISO FHL2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 9:45,388,979...45,462,530
Ensembl chr 9:45,388,981...45,431,192
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A decreases expression ISO Carmustine results in decreased expression of FKBP1A mRNA CTD PMID:15980968 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression EXP Carmustine results in increased expression of FKBP5 mRNA CTD PMID:16005536 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha decreases expression
increases expression
ISO Carmustine results in decreased expression of FNTA mRNA
Carmustine results in increased expression of FNTA mRNA
CTD PMID:15980968 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
JBrowse link
G Foxf2 forkhead box F2 affects response to substance ISO FOXF2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr17:32,835,730...32,842,555 JBrowse link
G Foxj1 forkhead box J1 decreases expression ISO Carmustine results in decreased expression of FOXJ1 mRNA CTD PMID:15980968 NCBI chr10:101,566,299...101,570,249 JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
decreases response to substance
decreases expression
ISO Carmustine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of FTH1 mRNA]
FTH1 results in decreased susceptibility to Carmustine
Carmustine results in decreased expression of FTH1 mRNA
CTD PMID:15980968 PMID:16631525 PMID:21385903 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression ISO Carmustine results in decreased expression of FTL mRNA CTD PMID:15980968 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Fut8 fucosyltransferase 8 affects response to substance ISO FUT8 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:95,948,230...96,176,677
Ensembl chr 6:95,949,991...96,176,677
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase decreases expression ISO Carmustine results in decreased expression of FYN mRNA CTD PMID:15980968 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 decreases expression
affects response to substance
ISO Carmustine results in decreased expression of GABRA2 mRNA
GABRA2 mRNA affects the susceptibility to Carmustine
CTD PMID:15980968 PMID:16365179 NCBI chr14:37,096,995...37,230,030
Ensembl chr14:37,097,279...37,228,944
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 decreases expression ISO Carmustine results in decreased expression of GABRA6 mRNA CTD PMID:15980968 NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 affects response to substance ISO GALNT15 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:7,227,232...7,267,002
Ensembl chr16:7,227,271...7,267,014
JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression ISO Carmustine results in decreased expression of GAMT mRNA CTD PMID:15980968 NCBI chr 7:9,448,590...9,451,778
Ensembl chr 7:9,448,628...9,451,778
JBrowse link
G Garnl3 GTPase activating Rap/RanGAP domain-like 3 affects response to substance ISO GARNL3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:16,288,718...16,432,308
Ensembl chr 3:16,288,719...16,430,837
JBrowse link
G Gast gastrin decreases expression ISO Carmustine results in decreased expression of GAST mRNA CTD PMID:15980968 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Buthionine Sulfoximine co-treated with Carmustine] results in decreased activity of GCLC protein; [Carmustine co-treated with Buthionine Sulfoximine] results in decreased activity of GCLC protein CTD PMID:12967637 PMID:16288907 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gcm1 glial cells missing transcription factor 1 increases expression ISO Carmustine results in increased expression of GCM1 mRNA CTD PMID:15980968 NCBI chr 8:78,925,687...78,938,924
Ensembl chr 8:78,925,687...78,938,924
JBrowse link
G Gdi1 GDP dissociation inhibitor 1 increases expression ISO Carmustine results in increased expression of GDI1 mRNA CTD PMID:15980968 NCBI chr  X:152,087,611...152,094,274
Ensembl chr  X:152,087,444...152,094,272
JBrowse link
G Gdi2 GDP dissociation inhibitor 2 increases expression ISO Carmustine results in increased expression of GDI2 mRNA CTD PMID:15980968 NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366
JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases response to substance ISO GDNF protein results in decreased susceptibility to Carmustine CTD PMID:19138852 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
multiple interactions
ISO
EXP
Carmustine results in decreased expression of GFAP mRNA
Melatonin inhibits the reaction [Carmustine results in decreased expression of GFAP protein]
CTD PMID:15980968 PMID:17572393 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Ghsr growth hormone secretagogue receptor decreases expression ISO Carmustine results in decreased expression of GHSR mRNA CTD PMID:15980968 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Glrb glycine receptor, beta affects response to substance ISO GLRB mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:166,134,624...166,207,509
Ensembl chr 2:166,134,626...166,207,489
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases expression ISO Carmustine results in increased expression of GNRHR mRNA CTD PMID:15980968 NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
JBrowse link
G Golga2 golgin A2 decreases expression ISO Carmustine results in decreased expression of GOLGA2 mRNA CTD PMID:15980968 NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279
JBrowse link
G Golga4 golgin A4 increases expression ISO Carmustine results in increased expression of GOLGA4 mRNA CTD PMID:15980968 NCBI chr 8:118,208,200...118,285,003 JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta decreases expression ISO Carmustine results in decreased expression of GP1BB mRNA CTD PMID:15980968 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392
JBrowse link
G Gpr25 G protein-coupled receptor 25 decreases expression ISO Carmustine results in decreased expression of GPR25 mRNA CTD PMID:15980968 NCBI chr13:47,709,696...47,715,270
Ensembl chr13:47,713,592...47,714,671
JBrowse link
G Gpr32 G protein-coupled receptor 32 decreases expression ISO Carmustine results in decreased expression of GPR32 mRNA CTD PMID:15980968 NCBI chr 1:94,756,863...94,757,895 JBrowse link
G Gpr37 G protein-coupled receptor 37 decreases expression ISO Carmustine results in decreased expression of GPR37 mRNA CTD PMID:15980968 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001
JBrowse link
G Gpr65 G-protein coupled receptor 65 increases expression ISO Carmustine results in increased expression of GPR65 mRNA CTD PMID:15980968 NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512
JBrowse link
G Grb7 growth factor receptor bound protein 7 decreases expression ISO Carmustine results in decreased expression of GRB7 mRNA CTD PMID:15980968 NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052
JBrowse link
G Grn granulin precursor decreases expression ISO Carmustine results in decreased expression of GRN mRNA CTD PMID:15980968 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO
EXP
[Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Doxorubicin; [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to zinc chloride; Glutathione Disulfide inhibits the reaction [Carmustine results in decreased activity of GSR protein]; NADP affects the reaction [Carmustine results in decreased activity of GSR protein]
[Buthionine Sulfoximine co-treated with Carmustine] results in decreased activity of GSR protein; [Carmustine co-treated with Buthionine Sulfoximine] results in decreased activity of GSR protein; [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Streptozocin; [Carmustine results in decreased activity of GSR protein] which results in increased uptake of Calcium; MT2 protein inhibits the reaction [Carmustine results in decreased activity of GSR protein]; Zinc Sulfate inhibits the reaction [Carmustine results in decreased activity of GSR protein]
[[Carmustine results in decreased activity of GSR protein] which co-treated with Oligodeoxyribonucleotides analog] results in increased abundance of Glutathione Disulfide; [[Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein] which results in increased abundance of Glutathione Disulfide; [Carmustine results in decreased activity of GSR protein] which results in decreased susceptibility to chromium hexavalent ion; [Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein
CTD PMID:2116959 PMID:12114195 PMID:12433058 PMID:12477282 PMID:12632252 More... NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance
decreases response to substance
multiple interactions
ISO GSTM1 gene affects the susceptibility to Carmustine
GSTM1 protein results in decreased susceptibility to Carmustine
GSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]
CTD PMID:16087946 PMID:20067466 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases nitrosation ISO GSTM2 protein results in decreased nitrosation of Carmustine CTD PMID:11841793 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstm3 glutathione S-transferase mu 3 affects metabolic processing
decreases nitrosation
multiple interactions
ISO GSTM3 protein affects the metabolism of Carmustine
GSTM3 protein results in decreased nitrosation of Carmustine
GSTM3 protein results in decreased nitrosation of and results in decreased activity of Carmustine
CTD PMID:8395980 PMID:11841793 PMID:15247628
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
affects metabolic processing
decreases nitrosation
ISO GSTM3 protein results in decreased nitrosation of and results in decreased activity of Carmustine
GSTM3 protein affects the metabolism of Carmustine
GSTM3 protein results in decreased nitrosation of Carmustine
CTD PMID:8395980 PMID:11841793 PMID:15247628 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases response to substance
ISO GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]
GSTP1 protein results in decreased susceptibility to Carmustine
CTD PMID:12791655 PMID:16899598 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects response to substance
affects metabolic processing
decreases nitrosation
ISO GSTT1 protein affects the susceptibility to Carmustine
GSTT1 protein affects the metabolism of Carmustine
GSTT1 protein results in decreased nitrosation of Carmustine
CTD PMID:11841793 PMID:16874663 PMID:17827337 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 decreases expression ISO Carmustine results in decreased expression of GTF2F1 mRNA CTD PMID:15980968 NCBI chr 9:1,844,027...1,853,455
Ensembl chr 9:1,843,901...1,853,423
JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 decreases expression EXP Carmustine results in decreased expression of GUCY1B2 mRNA CTD PMID:16005536 NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441
JBrowse link
G H2ax H2A.X variant histone decreases expression
increases phosphorylation
multiple interactions
affects localization
ISO Carmustine results in decreased expression of H2AX mRNA
Carmustine results in increased phosphorylation of H2AX protein
MDM4 protein promotes the reaction [Carmustine affects the localization of H2AX protein]; MDM4 protein promotes the reaction [Carmustine results in increased phosphorylation of H2AX protein]
CTD PMID:15980968 PMID:20472715 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 decreases expression EXP Carmustine results in decreased expression of HACL1 mRNA CTD PMID:16005536 NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO Carmustine results in decreased expression of HADH mRNA CTD PMID:15980968 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hagh hydroxyacyl glutathione hydrolase decreases expression ISO Carmustine results in decreased expression of HAGH mRNA CTD PMID:15980968 NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504
JBrowse link
G Hcfc1 host cell factor C1 decreases expression ISO Carmustine results in decreased expression of HCFC1 mRNA CTD PMID:15980968 NCBI chr  X:151,687,779...151,712,688
Ensembl chr  X:151,687,779...151,712,638
JBrowse link
G Hhat hedgehog acyltransferase affects response to substance ISO HHAT mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr13:104,024,507...104,283,581
Ensembl chr13:104,010,916...104,282,893
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases response to substance
multiple interactions
EXP HIF1A protein results in decreased susceptibility to Carmustine
[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine; [Deferoxamine results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine
CTD PMID:14980978 PMID:15965067 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgn2 high mobility group nucleosomal binding domain 2 decreases expression ISO Carmustine results in decreased expression of HMGN2 mRNA CTD PMID:15980968 NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Carmustine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA] CTD PMID:16631525 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf1a HNF1 homeobox A decreases expression ISO Carmustine results in decreased expression of HNF1A mRNA CTD PMID:15980968 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hoxa4 homeo box A4 decreases expression ISO Carmustine results in decreased expression of HOXA4 mRNA CTD PMID:15980968 NCBI chr 4:81,289,677...81,291,685
Ensembl chr 4:81,289,682...81,291,685
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis ISO Carmustine results in increased mutagenesis of HPRT1 gene CTD PMID:17116724 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Icam5 intercellular adhesion molecule 5 decreases expression ISO Carmustine results in decreased expression of ICAM5 mRNA CTD PMID:15980968 NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588
JBrowse link
G Ids iduronate 2-sulfatase decreases expression ISO Carmustine results in decreased expression of IDS mRNA CTD PMID:15980968 NCBI chr  X:149,025,977...149,046,639
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Ier3 immediate early response 3 decreases expression ISO Carmustine results in decreased expression of IER3 mRNA CTD PMID:15980968 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression
increases expression
ISO Carmustine results in decreased expression of IGF1 protein
Carmustine results in increased expression of IGF1 protein
CTD PMID:15286697 PMID:18443378 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf2 insulin-like growth factor 2 affects response to substance ISO IGF2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP Carmustine results in decreased expression of IGFBP3 mRNA CTD PMID:16005536 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma decreases expression ISO Carmustine results in decreased expression of IKBKG mRNA CTD PMID:15980968 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Carmustine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:12688424 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Carmustine promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:11970852 PMID:12433058 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 affects response to substance ISO IL1R1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il6 interleukin 6 affects response to substance
multiple interactions
ISO
EXP
IL6 mRNA affects the susceptibility to Carmustine
Carmustine promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
Carmustine promotes the reaction [Oligodeoxyribonucleotides analog results in increased secretion of IL6 protein]
CTD PMID:11970852 PMID:12433058 PMID:12477282 PMID:16365179 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Inhba inhibin subunit beta A affects response to substance ISO INHBA mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 decreases expression ISO Carmustine results in decreased expression of INPPL1 mRNA CTD PMID:15980968 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO Carmustine results in decreased expression of INSIG1 mRNA CTD PMID:15980968 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insl3 insulin-like 3 decreases expression ISO Carmustine results in decreased expression of INSL3 mRNA CTD PMID:15980968 NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
JBrowse link
G Ipo4 importin 4 affects response to substance ISO IPO4 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr15:29,117,365...29,127,382
Ensembl chr15:29,117,365...29,127,285
JBrowse link
G Irag2 inositol 1,4,5-triphosphate receptor associated 2 decreases expression ISO Carmustine results in decreased expression of IRAG2 mRNA CTD PMID:15980968 NCBI chr 4:178,088,902...178,143,569
Ensembl chr 4:178,088,507...178,143,557
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO Carmustine results in decreased expression of IRS1 mRNA CTD PMID:15980968 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Islr immunoglobulin superfamily containing leucine-rich repeat decreases expression ISO
EXP
Carmustine results in decreased expression of ISLR mRNA CTD PMID:15980968 PMID:16005536 NCBI chr 8:58,571,155...58,574,128
Ensembl chr 8:58,570,777...58,574,130
JBrowse link
G Itga3 integrin subunit alpha 3 decreases expression ISO Carmustine results in decreased expression of ITGA3 mRNA CTD PMID:15980968 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Carmustine results in decreased expression of ITGB1 protein CTD PMID:18443378 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3 integrin subunit beta 3 increases response to substance
multiple interactions
ISO
EXP
ITGB3 protein results in increased susceptibility to Carmustine
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ITGB3 protein results in increased susceptibility to Carmustine]
CTD PMID:21332719 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 decreases expression ISO Carmustine results in decreased expression of ITIH1 mRNA CTD PMID:15980968 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363
JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 multiple interactions EXP [Carmustine co-treated with Buthionine Sulfoximine] results in decreased expression of KCNA4 protein CTD PMID:16288907 NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162
JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 affects response to substance ISO KCNAB2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:162,899,511...162,988,057
Ensembl chr 5:162,901,896...162,988,243
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 multiple interactions EXP [Carmustine co-treated with Buthionine Sulfoximine] results in decreased expression of KCND2 mRNA; [Carmustine co-treated with Buthionine Sulfoximine] results in decreased expression of KCND2 protein CTD PMID:16288907 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases expression ISO Carmustine results in decreased expression of KCNH2 mRNA CTD PMID:15980968 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kif2c kinesin family member 2C decreases expression EXP Carmustine results in decreased expression of KIF2C mRNA CTD PMID:16005536 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Kif5a kinesin family member 5A decreases expression ISO Carmustine results in decreased expression of KIF5A mRNA CTD PMID:15980968 NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858
JBrowse link
G Krt17 keratin 17 decreases expression ISO Carmustine results in decreased expression of KRT17 mRNA CTD PMID:15980968 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt31 keratin 31 decreases expression ISO Carmustine results in decreased expression of KRT31 mRNA CTD PMID:15980968 NCBI chr10:84,979,130...84,982,832
Ensembl chr10:84,979,352...84,982,832
JBrowse link
G Krt8 keratin 8 affects response to substance ISO KRT8 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lad1 ladinin 1 decreases expression ISO Carmustine results in decreased expression of LAD1 mRNA CTD PMID:15980968 NCBI chr13:47,249,605...47,263,967
Ensembl chr13:47,249,605...47,263,967
JBrowse link
G Lair1 leukocyte-associated immunoglobulin-like receptor 1 increases expression ISO Carmustine results in increased expression of LAIR1 mRNA CTD PMID:15980968 NCBI chr 1:70,068,571...70,187,851
Ensembl chr 1:70,157,681...70,185,807
JBrowse link
G Lamb3 laminin subunit beta 3 decreases expression ISO Carmustine results in decreased expression of LAMB3 mRNA CTD PMID:15980968 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
JBrowse link
G Lbp lipopolysaccharide binding protein affects response to substance ISO LBP mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lcn2 lipocalin 2 increases response to substance
multiple interactions
ISO
EXP
LCN2 protein results in increased susceptibility to Carmustine
[LCN2 protein co-treated with Carmustine] results in increased cleavage of and results in increased activity of CASP3 protein; LCN2 protein promotes the reaction [Carmustine results in decreased phosphorylation of AKT1 protein]
CTD PMID:19860839 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Ldlr low density lipoprotein receptor affects uptake ISO LDLR protein affects the uptake of Carmustine analog CTD PMID:12107554 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases response to substance ISO LIF mRNA results in increased susceptibility to Carmustine CTD PMID:16365179 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lig1 DNA ligase 1 decreases expression EXP Carmustine results in decreased expression of LIG1 mRNA CTD PMID:16005536 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
JBrowse link
G Lins1 lines homolog 1 affects response to substance ISO LINS1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:120,267,586...120,295,013
Ensembl chr 1:120,267,693...120,293,607
JBrowse link
G Lman1l lectin, mannose-binding, 1 like affects response to substance ISO LMAN1L mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:58,010,839...58,029,599
Ensembl chr 8:58,010,839...58,023,681
JBrowse link
G Lmtk2 lemur tyrosine kinase 2 affects response to substance ISO LMTK2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:10,426,772...10,508,750
Ensembl chr12:10,426,777...10,508,750
JBrowse link
G Lmx1b LIM homeobox transcription factor 1 beta decreases expression ISO Carmustine results in decreased expression of LMX1B mRNA CTD PMID:15980968 NCBI chr 3:16,862,195...16,940,899
Ensembl chr 3:16,862,195...16,940,899
JBrowse link
G LOC691272 similar to reproductive homeobox on X chromosome, 11 decreases expression ISO Carmustine results in decreased expression of SHOX mRNA CTD PMID:15980968 NCBI chr  X:116,688,163...116,695,111
Ensembl chr  X:116,688,163...116,695,058
JBrowse link
G Loxl1 lysyl oxidase-like 1 decreases expression ISO Carmustine results in decreased expression of LOXL1 mRNA CTD PMID:15980968 NCBI chr 8:58,692,592...58,716,356
Ensembl chr 8:58,692,593...58,716,356
JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 decreases expression ISO Carmustine results in decreased expression of LRCH4 mRNA CTD PMID:15980968 NCBI chr12:19,057,582...19,072,573
Ensembl chr12:19,057,587...19,068,577
JBrowse link
G Lsp1 lymphocyte-specific protein 1 decreases expression EXP Carmustine results in decreased expression of LSP1 mRNA CTD PMID:16005536 NCBI chr 1:197,614,585...197,648,414
Ensembl chr 1:197,614,687...197,648,416
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 decreases expression ISO Carmustine results in decreased expression of MAD1L1 mRNA CTD PMID:15980968 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 decreases expression ISO Carmustine results in decreased expression of MAP4K2 mRNA CTD PMID:15980968 NCBI chr 1:203,645,098...203,660,515
Ensembl chr 1:203,645,153...203,660,331
JBrowse link
G Mapk10 mitogen activated protein kinase 10 decreases expression ISO Carmustine results in decreased expression of MAPK10 mRNA CTD PMID:15980968 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
JBrowse link
G Masp1 MBL associated serine protease 1 affects response to substance ISO MASP1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
JBrowse link
G Mat1a methionine adenosyltransferase 1A decreases expression ISO Carmustine results in decreased expression of MAT1A mRNA CTD PMID:15980968 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
JBrowse link
G Mdk midkine decreases expression ISO Carmustine results in decreased expression of MDK mRNA CTD PMID:15980968 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mdm4 MDM4 regulator of p53 multiple interactions
decreases response to substance
ISO [Carmustine co-treated with MDM4 protein] results in increased expression of POLH protein; MDM4 protein promotes the reaction [Carmustine affects the localization of H2AX protein]; MDM4 protein promotes the reaction [Carmustine results in increased expression of CDKN1A protein]; MDM4 protein promotes the reaction [Carmustine results in increased expression of TP53 protein]; MDM4 protein promotes the reaction [Carmustine results in increased phosphorylation of H2AX protein]
MDM4 protein results in decreased susceptibility to Carmustine
CTD PMID:20472715 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226
JBrowse link
G Mecom MDS1 and EVI1 complex locus affects response to substance ISO EVI1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590
JBrowse link
G Med1 mediator complex subunit 1 decreases expression ISO Carmustine results in decreased expression of MED1 mRNA CTD PMID:15980968 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Mgat3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase decreases expression ISO Carmustine results in decreased expression of MGAT3 mRNA CTD PMID:15980968 NCBI chr 7:111,708,353...111,761,825
Ensembl chr 7:111,675,730...111,762,026
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases alkylation
increases response to substance
multiple interactions
decreases expression
decreases response to substance
affects response to substance
decreases activity
ISO
EXP
Carmustine results in increased alkylation of MGMT protein
MGMT mutant form results in increased susceptibility to Carmustine
[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Carmustine; [MGMT protein mutant form co-treated with FECH protein] results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]; [O(6)-benzyl-2'-deoxyguanosine results in decreased activity of MGMT protein] which results in increased susceptibility to Carmustine; [O(6)-benzyl-N-acetylguanosine results in decreased activity of MGMT protein] which results in increased susceptibility to Carmustine; [O(6)-benzylguanine co-treated with Carmustine] results in decreased activity of MGMT protein; [O(6)-benzylguanine results in decreased activity of MGMT protein] which results in increased susceptibility to Carmustine; [Tamoxifen results in increased degradation of MGMT protein] which results in increased susceptibility to Carmustine; MGMT protein mutant form results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]; MGMT protein mutant form results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]; MGMT protein results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]; MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]; O(6)-benzylguanine inhibits the reaction [MGMT protein mutant form results in decreased susceptibility to Carmustine]
Carmustine results in decreased expression of MGMT protein
MGMT protein results in decreased susceptibility to Carmustine
[O(6)-benzylguanine results in decreased activity of MGMT protein] which affects the susceptibility to Carmustine; MGMT protein mutant form results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]; MGMT protein results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]
MGMT protein affects the susceptibility to Carmustine
Carmustine results in decreased activity of MGMT protein
MGMT mRNA results in decreased susceptibility to Carmustine; MGMT protein mutant form results in decreased susceptibility to Carmustine; MGMT protein results in decreased susceptibility to Carmustine; MGMT protein results in decreased susceptibility to Carmustine analog; MGMT results in decreased susceptibility to Carmustine
MGMT gene modified form affects the susceptibility to Carmustine; MGMT promoter modified form affects the susceptibility to Carmustine; MGMT protein affects the susceptibility to Carmustine
CTD PMID:8823159 PMID:9918549 PMID:11792417 PMID:11945064 PMID:12036916 More... NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 affects response to substance ISO MGST2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
JBrowse link
G Mlh1 mutL homolog 1 affects response to substance ISO MLH1 protein affects the susceptibility to Carmustine CTD PMID:18430789 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mlph melanophilin affects response to substance ISO MLPH mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 9:91,507,410...91,542,984
Ensembl chr 9:91,507,591...91,542,983
JBrowse link
G Mpg N-methylpurine-DNA glycosylase decreases response to substance ISO MPG protein results in decreased susceptibility to Carmustine CTD PMID:16288039 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520
JBrowse link
G Mpst mercaptopyruvate sulfurtransferase affects response to substance ISO MPST mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141
JBrowse link
G Msh2 mutS homolog 2 affects response to substance ISO MSH2 protein affects the susceptibility to Carmustine CTD PMID:18430789 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msr1 macrophage scavenger receptor 1 decreases expression ISO Carmustine results in decreased expression of MSR1 mRNA CTD PMID:15980968 NCBI chr16:52,717,775...52,802,890
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mt2A metallothionein 2A affects response to substance
multiple interactions
ISO
EXP
MT2A mRNA affects the susceptibility to Carmustine
MT2 protein inhibits the reaction [Carmustine results in decreased activity of GSR protein]; MT2 protein inhibits the reaction [Carmustine results in increased expression of TNF protein]
MT2 protein affects the susceptibility to Carmustine
CTD PMID:16365179 PMID:18528683 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mturn maturin, neural progenitor differentiation regulator homolog affects response to substance ISO MTURN mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:83,807,528...83,828,494
Ensembl chr 4:83,807,579...83,824,950
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming decreases expression ISO Carmustine results in decreased expression of MUC2 mRNA CTD PMID:15980968 NCBI chr 1:196,796,257...196,831,740 JBrowse link
G Mug1 murinoglobulin 1 decreases expression ISO Carmustine results in decreased expression of PZP mRNA CTD PMID:15980968 NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051
JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression ISO Carmustine results in decreased expression of MVD mRNA CTD PMID:15980968 NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression EXP Carmustine results in increased expression of MYBL2 mRNA CTD PMID:16005536 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Mybph myosin binding protein H decreases expression ISO Carmustine results in decreased expression of MYBPH mRNA CTD PMID:15980968 NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor decreases expression ISO Carmustine results in decreased expression of MYD88 mRNA CTD PMID:15980968 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Myod1 myogenic differentiation 1 decreases expression ISO Carmustine results in decreased expression of MYOD1 mRNA CTD PMID:15980968 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
JBrowse link
G Myog myogenin decreases expression ISO Carmustine results in decreased expression of MYOG mRNA CTD PMID:15980968 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist affects response to substance ISO NBL1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 decreases expression ISO Carmustine results in decreased expression of NDUFC1 mRNA CTD PMID:15980968 NCBI chr 2:135,447,067...135,450,950 JBrowse link
G Nek6 NIMA-related kinase 6 increases expression EXP Carmustine results in increased expression of NEK6 mRNA CTD PMID:16005536 NCBI chr 3:22,284,269...22,356,302
Ensembl chr 3:22,284,279...22,395,990
JBrowse link
G Nes nestin increases expression
multiple interactions
EXP Carmustine results in increased expression of NES protein
Melatonin inhibits the reaction [Carmustine results in increased expression of NES protein]
CTD PMID:17572393 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 affects response to substance ISO NFAT5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects response to substance ISO [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Carmustine CTD PMID:19303893 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfib nuclear factor I/B affects response to substance ISO NFIB mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:96,759,208...96,973,092
Ensembl chr 5:96,764,653...96,975,479
JBrowse link
G Nfix nuclear factor I X affects response to substance ISO NFIX mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO
EXP
Carmustine results in increased activity of [NFKB1 protein binds to NFKB1 protein]; Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]]
Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; Carmustine inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]]
[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to NFKB1 protein]; [Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]; diphenyleneiodonium inhibits the reaction [[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; diphenyleneiodonium inhibits the reaction [[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD PMID:11970852 PMID:12433058 PMID:12477282 PMID:12675310 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases response to substance
ISO
EXP
NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]]
Carmustine inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; Carmustine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
NFKBIA gene mutant form results in increased susceptibility to Carmustine; NFKBIA mRNA results in increased susceptibility to Carmustine
CTD PMID:11970852 PMID:12433058 PMID:12675310 PMID:16365179 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngef neuronal guanine nucleotide exchange factor decreases expression EXP Carmustine results in decreased expression of NGEF mRNA CTD PMID:16005536 NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914
JBrowse link
G Ngf nerve growth factor affects activity EXP Carmustine affects the activity of NGF protein CTD PMID:15935206 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nid2 nidogen 2 decreases expression EXP Carmustine results in decreased expression of NID2 mRNA CTD PMID:16005536 NCBI chr15:4,458,082...4,513,808
Ensembl chr15:4,458,084...4,513,843
JBrowse link
G Nin ninein affects response to substance ISO NIN mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:88,525,405...88,627,710
Ensembl chr 6:88,525,742...88,627,639
JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 affects response to substance ISO NKD2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821
JBrowse link
G Nkx2-2 NK2 homeobox 2 decreases expression ISO Carmustine results in decreased expression of NKX2-2 mRNA CTD PMID:15980968 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases response to substance
ISO
EXP
[NOS2 protein results in increased chemical synthesis of S-Nitrosoglutathione] which results in decreased susceptibility to Carmustine
NOS2 protein results in decreased susceptibility to Carmustine
[Carmustine co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitrites]; [Carmustine co-treated with Buthionine Sulfoximine] inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Buthionine Sulfoximine promotes the reaction [Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]]; Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Carmustine]
CTD PMID:7532384 PMID:15110396 PMID:15965067 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npas1 neuronal PAS domain protein 1 decreases expression ISO Carmustine results in decreased expression of NPAS1 mRNA CTD PMID:15980968 NCBI chr 1:77,167,375...77,187,887
Ensembl chr 1:77,167,381...77,186,762
JBrowse link
G Npas2 neuronal PAS domain protein 2 affects response to substance ISO NPAS2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320
JBrowse link
G Npl N-acetylneuraminate pyruvate lyase affects response to substance ISO NPL mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr13:65,655,099...65,697,464
Ensembl chr13:65,655,118...65,697,372
JBrowse link
G Npr1 natriuretic peptide receptor 1 decreases expression EXP Carmustine results in decreased expression of NPR1 mRNA CTD PMID:16005536 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 affects response to substance ISO NR2F1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 affects expression EXP Carmustine affects the expression of NR4A2 mRNA CTD PMID:19174181 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nrtn neurturin decreases expression ISO Carmustine results in decreased expression of NRTN mRNA CTD PMID:15980968 NCBI chr 9:1,581,860...1,587,835
Ensembl chr 9:1,581,975...1,583,102
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases response to substance ISO OGG1 protein results in decreased susceptibility to Carmustine CTD PMID:11181913 PMID:11741815 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Omp olfactory marker protein decreases expression ISO Carmustine results in decreased expression of OMP mRNA CTD PMID:15980968 NCBI chr 1:152,440,278...152,440,828
Ensembl chr 1:152,433,652...152,441,922
JBrowse link
G Orm1 orosomucoid 1 increases expression EXP Carmustine results in increased expression of ORM1 mRNA CTD PMID:16005536 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G P3h3 prolyl 3-hydroxylase 3 affects response to substance ISO P3H3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:157,646,238...157,662,035 JBrowse link
G Paep progestagen associated endometrial protein decreases expression ISO Carmustine results in decreased expression of PAEP mRNA CTD PMID:15980968 NCBI chr 3:8,531,136...8,534,430
Ensembl chr 3:8,531,138...8,534,430
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO Disulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein] CTD PMID:24193513 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax8 paired box 8 decreases expression ISO Carmustine results in decreased expression of PAX8 mRNA CTD PMID:15980968 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Pbx2 PBX homeobox 2 decreases expression ISO Carmustine results in decreased expression of PBX2 mRNA CTD PMID:15980968 NCBI chr20:4,151,500...4,156,425
Ensembl chr20:4,151,500...4,156,425
JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 decreases expression ISO Carmustine results in decreased expression of PCBD1 mRNA CTD PMID:15980968 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292
JBrowse link
G Pcdhb2 protocadherin beta 2 affects response to substance ISO PCDHB2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr18:29,005,996...29,008,782
Ensembl chr18:29,005,996...29,008,782
JBrowse link
G Pcdhgc3 protocadherin gamma subfamily C, 3 decreases expression ISO Carmustine results in decreased expression of PCDHGC3 mRNA CTD PMID:15980968 NCBI chr18:29,633,016...29,667,865 JBrowse link
G Pcolce procollagen C-endopeptidase enhancer decreases expression ISO Carmustine results in decreased expression of PCOLCE mRNA CTD PMID:15980968 NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline decreases expression ISO Carmustine results in decreased expression of PCYT1A mRNA CTD PMID:15980968 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357
JBrowse link
G Pde5a phosphodiesterase 5A affects response to substance ISO PDE5A mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pdgfb platelet derived growth factor subunit B increases expression ISO Carmustine results in increased expression of PDGFB protein CTD PMID:15286697 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 decreases expression ISO Carmustine results in decreased expression of PFKFB2 mRNA CTD PMID:15980968 NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression ISO Carmustine results in decreased expression of PFKM mRNA CTD PMID:15980968 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pfn1 profilin 1 decreases expression ISO Carmustine results in decreased expression of PFN1 mRNA CTD PMID:15980968 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Pgm2 phosphoglucomutase 2 affects response to substance ISO PGM2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr14:44,166,314...44,199,823
Ensembl chr14:44,164,425...44,199,967
JBrowse link
G Phc2 polyhomeotic homolog 2 affects response to substance ISO PHC2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:141,000,604...141,099,268
Ensembl chr 5:141,050,842...141,099,268
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 affects response to substance ISO PHLDA1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 affects response to substance ISO PIK3C3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta affects response to substance ISO PIK3CD mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 increases expression ISO Carmustine results in increased expression of PIK3R3 mRNA CTD PMID:15980968 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 affects response to substance ISO PITPNC1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:92,163,558...92,428,971 JBrowse link
G Pknox2 PBX/knotted 1 homeobox 2 decreases expression EXP Carmustine results in decreased expression of PKNOX2 mRNA CTD PMID:16005536 NCBI chr 8:36,600,633...36,863,131
Ensembl chr 8:36,600,636...36,790,940
JBrowse link
G Pkp2 plakophilin 2 increases expression EXP Carmustine results in increased expression of PKP2 mRNA CTD PMID:16005536 NCBI chr11:84,661,783...84,727,730 JBrowse link
G Pkp3 plakophilin 3 affects response to substance ISO PKP3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:196,187,835...196,198,844
Ensembl chr 1:196,187,835...196,198,844
JBrowse link
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 affects response to substance ISO PLEKHG5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:162,577,999...162,621,518
Ensembl chr 5:162,578,071...162,621,513
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression EXP Carmustine results in increased expression of PNPLA2 mRNA CTD PMID:16005536 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit affects response to substance ISO POLG2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008
JBrowse link
G Polh DNA polymerase eta multiple interactions ISO [Carmustine co-treated with MDM4 protein] results in increased expression of POLH protein CTD PMID:20472715 NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723
JBrowse link
G Polr2e RNA polymerase II, I and III subunit E decreases expression ISO Carmustine results in decreased expression of POLR2E mRNA CTD PMID:15980968 NCBI chr 7:9,666,695...9,670,638
Ensembl chr 7:9,666,716...9,670,643
JBrowse link
G Popdc3 popeye domain containing 3 affects response to substance ISO POPDC3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr20:48,772,382...48,800,364
Ensembl chr20:48,772,462...48,800,593
JBrowse link
G Ppm1g protein phosphatase, Mg2+/Mn2+ dependent, 1G decreases expression ISO Carmustine results in decreased expression of PPM1G mRNA CTD PMID:15980968 NCBI chr 6:25,153,556...25,173,763
Ensembl chr 6:25,153,556...25,173,761
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO Carmustine results in decreased expression of PRC1 mRNA CTD PMID:17374387 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 affects response to substance ISO PREX1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 affects response to substance ISO PRKAA2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Prl prolactin decreases expression ISO Carmustine results in decreased expression of PRL mRNA CTD PMID:15980968 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prm2 protamine 2 decreases expression ISO Carmustine results in decreased expression of PRM2 mRNA CTD PMID:15980968 NCBI chr10:4,876,398...4,876,834
Ensembl chr10:4,873,372...4,877,026
JBrowse link
G Prph peripherin decreases expression EXP Carmustine results in decreased expression of PRPH mRNA CTD PMID:16005536 NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136
JBrowse link
G Prrx2 paired related homeobox 2 affects response to substance ISO PRRX2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:14,132,511...14,168,535
Ensembl chr 3:14,094,004...14,168,535
JBrowse link
G Prss12 serine protease 12 affects response to substance ISO PRSS12 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:211,624,134...211,684,126
Ensembl chr 2:211,624,134...211,684,126
JBrowse link
G Pth2r parathyroid hormone 2 receptor decreases expression EXP Carmustine results in decreased expression of PTH2R mRNA CTD PMID:16005536 NCBI chr 9:66,706,050...66,810,034
Ensembl chr 9:66,706,050...66,810,036
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 decreases expression ISO Carmustine results in decreased expression of PTPN3 mRNA CTD PMID:15980968 NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443
JBrowse link
G Qpct glutaminyl-peptide cyclotransferase affects response to substance ISO QPCT mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:15,964,656...15,996,925
Ensembl chr 6:15,964,657...15,996,711
JBrowse link
G Rab27b RAB27B, member RAS oncogene family affects response to substance ISO RAB27B mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr18:63,597,554...63,794,124
Ensembl chr18:63,600,937...63,757,180
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO Carmustine results in decreased expression of RAD23A mRNA CTD PMID:15980968 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO Carmustine results in decreased expression of RAD51 mRNA CTD PMID:15980968 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad9a RAD9 checkpoint clamp component A decreases expression ISO Carmustine results in decreased expression of RAD9A mRNA CTD PMID:15980968 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
JBrowse link
G Rbm19 RNA binding motif protein 19 affects response to substance ISO RBM19 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:36,365,775...36,451,033
Ensembl chr12:36,365,772...36,450,993
JBrowse link
G Rcn1 reticulocalbin 1 decreases expression ISO Carmustine results in decreased expression of RCN1 mRNA CTD PMID:15980968 NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:91,841,052...91,855,295
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions EXP Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of REL protein] CTD PMID:11970852 PMID:12433058 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]]
Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; Carmustine inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]]
[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]; diphenyleneiodonium inhibits the reaction [[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD PMID:11970852 PMID:12433058 PMID:12477282 PMID:12675310 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions EXP Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of RELB protein] CTD PMID:11970852 PMID:12433058 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Rfc3 replication factor C subunit 3 decreases expression EXP Carmustine results in decreased expression of RFC3 mRNA CTD PMID:16005536 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778
JBrowse link
G Rgcc regulator of cell cycle affects response to substance ISO RGCC mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Rgp1 RGP1 homolog, RAB6A GEF complex partner 1 affects response to substance ISO RGP1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:57,834,467...57,843,087
Ensembl chr 5:57,834,629...57,843,086
JBrowse link
G Rgr retinal G protein coupled receptor decreases expression ISO Carmustine results in decreased expression of RGR mRNA CTD PMID:15980968 NCBI chr16:12,801,594...12,816,402
Ensembl chr16:12,801,594...12,816,223
JBrowse link
G Rhobtb3 Rho-related BTB domain containing 3 affects response to substance ISO RHOBTB3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:5,363,388...5,419,164
Ensembl chr 2:5,363,388...5,419,041
JBrowse link
G Rit2 Ras-like without CAAX 2 decreases expression ISO Carmustine results in decreased expression of RIT2 mRNA CTD PMID:15980968 NCBI chr18:22,565,403...22,921,648
Ensembl chr18:22,565,404...22,921,648
JBrowse link
G Rnase4 ribonuclease A family member 4 increases expression ISO Carmustine results in increased expression of RNASE4 mRNA CTD PMID:15980968 NCBI chr15:24,312,765...24,330,116
Ensembl chr15:24,312,464...24,330,117
JBrowse link
G Rorb RAR-related orphan receptor B affects expression EXP Carmustine affects the expression of RORB mRNA CTD PMID:19174181 NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 affects response to substance ISO SAT1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Scamp5 secretory carrier membrane protein 5 affects response to substance ISO SCAMP5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:57,845,831...57,884,516
Ensembl chr 8:57,846,659...57,872,027
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 increases expression EXP Carmustine results in increased expression of SCN1B mRNA CTD PMID:16005536 NCBI chr 1:86,353,917...86,363,836
Ensembl chr 1:86,353,917...86,363,739
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 affects response to substance ISO SCN8A mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:131,982,152...132,156,075
Ensembl chr 7:131,982,480...132,151,292
JBrowse link
G Sdc1 syndecan 1 affects response to substance ISO SDC1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264
JBrowse link
G Sema3a semaphorin 3A affects response to substance ISO SEMA3A mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
JBrowse link
G Septin4 septin 4 decreases expression EXP Carmustine results in decreased expression of SEPTIN4 mRNA CTD PMID:16005536 NCBI chr10:72,366,729...72,390,764
Ensembl chr10:72,366,873...72,390,768
JBrowse link
G Septin5 septin 5 decreases expression ISO Carmustine results in decreased expression of SEPTIN5 mRNA CTD PMID:15980968 NCBI chr11:82,373,601...82,379,393
Ensembl chr11:82,369,754...82,379,393
JBrowse link
G Serpinb1a serpin family B member 1A affects response to substance ISO SERPINB1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
JBrowse link
G Sf1 splicing factor 1 affects response to substance ISO SF1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression ISO Carmustine results in decreased expression of SFPQ mRNA CTD PMID:15980968 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sgca sarcoglycan, alpha decreases expression ISO Carmustine results in decreased expression of SGCA mRNA CTD PMID:15980968 NCBI chr10:79,904,698...79,922,813
Ensembl chr10:79,908,738...79,922,813
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 decreases expression ISO Carmustine results in decreased expression of SHMT2 mRNA CTD PMID:15980968 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
G Slc10a1 solute carrier family 10 member 1 increases expression ISO Carmustine results in increased expression of SLC10A1 mRNA CTD PMID:15980968 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases expression EXP Carmustine results in decreased expression of SLC12A1 mRNA CTD PMID:17727784 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc12a2 solute carrier family 12 member 2 increases expression EXP Carmustine results in increased expression of SLC12A2 mRNA CTD PMID:17727784 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) affects response to substance ISO SLC14A1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146
JBrowse link
G Slc15a2 solute carrier family 15 member 2 affects response to substance ISO SLC15A2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225
JBrowse link
G Slc16a2 solute carrier family 16 member 2 increases expression ISO Carmustine results in increased expression of SLC16A2 mRNA CTD PMID:15980968 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771
JBrowse link
G Slc19a2 solute carrier family 19 member 2 decreases expression EXP Carmustine results in decreased expression of SLC19A2 mRNA CTD PMID:16005536 NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172
JBrowse link
G Slc22a5 solute carrier family 22 member 5 affects response to substance ISO SLC22A5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc30a3 solute carrier family 30 member 3 decreases expression ISO Carmustine results in decreased expression of SLC30A3 mRNA CTD PMID:15980968 NCBI chr 6:25,264,310...25,284,720
Ensembl chr 6:25,275,528...25,284,720
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression EXP Carmustine results in increased expression of SLC3A2 mRNA CTD PMID:16005536 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc6a2 solute carrier family 6 member 2 increases expression ISO Carmustine results in increased expression of SLC6A2 mRNA CTD PMID:15980968 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression ISO Carmustine results in decreased expression of SLCO1A2 mRNA CTD PMID:15980968 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor affects response to substance ISO SLPI mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Smarcd1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 increases expression ISO Carmustine results in increased expression of SMARCD1 mRNA CTD PMID:15980968 NCBI chr 7:130,829,783...130,840,323
Ensembl chr 7:130,829,768...130,840,323
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 increases expression ISO Carmustine results in increased expression of SMPD2 mRNA CTD PMID:15980968 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441
JBrowse link
G Snapc1 small nuclear RNA activating complex, polypeptide 1 increases expression ISO Carmustine results in increased expression of SNAPC1 mRNA CTD PMID:15980968 NCBI chr 6:92,684,785...92,710,772
Ensembl chr 6:92,684,752...92,707,746
JBrowse link
G Snapc3 small nuclear RNA activating complex, polypeptide 3 increases expression ISO Carmustine results in increased expression of SNAPC3 mRNA CTD PMID:15980968 NCBI chr 5:97,817,827...97,868,494
Ensembl chr 5:97,817,947...97,844,650
JBrowse link
G Sncg synuclein, gamma increases expression ISO Carmustine results in increased expression of SNCG mRNA CTD PMID:15980968 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 increases expression ISO Carmustine results in increased expression of SNRPB2 mRNA CTD PMID:15980968 NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Carmustine results in decreased expression of SOCS1 mRNA CTD PMID:17374387 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Sod1 superoxide dismutase 1 decreases activity ISO Carmustine results in decreased activity of SOD1 protein CTD PMID:19856331 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 affects response to substance
increases response to substance
multiple interactions
decreases activity
ISO SOD2 mRNA affects the susceptibility to Carmustine
SOD2 protein results in increased susceptibility to Carmustine
Pyruvates inhibits the reaction [SOD2 protein results in increased susceptibility to Carmustine]
Carmustine results in decreased activity of SOD2 protein
CTD PMID:8877099 PMID:16365179 PMID:19856331 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 decreases expression ISO Carmustine results in decreased expression of SORBS2 mRNA CTD PMID:15980968 NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514
JBrowse link
G Sox9 SRY-box transcription factor 9 affects response to substance ISO SOX9 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Sparc secreted protein acidic and cysteine rich affects response to substance ISO SPARC mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Speg striated muscle enriched protein kinase decreases expression ISO Carmustine results in decreased expression of SPEG mRNA CTD PMID:15980968 NCBI chr 9:76,865,714...76,923,170
Ensembl chr 9:76,865,754...76,923,144
JBrowse link
G Spen spen family transcriptional repressor affects response to substance ISO SPEN mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:153,775,287...153,848,677
Ensembl chr 5:153,776,234...153,848,811
JBrowse link
G Sqle squalene epoxidase affects response to substance ISO SQLE mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Srp14 signal recognition particle 14 decreases expression ISO Carmustine results in decreased expression of SRP14 mRNA CTD PMID:15980968 NCBI chr 3:105,442,184...105,445,875
Ensembl chr 3:105,442,198...105,445,859
JBrowse link
G Sry sex determining region Y decreases expression ISO Carmustine results in decreased expression of SRY mRNA CTD PMID:15980968
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 affects response to substance ISO ST3GAL1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 increases expression ISO Carmustine results in increased expression of ST6GAL1 mRNA CTD PMID:15980968 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 increases expression ISO Carmustine results in increased expression of ST8SIA1 mRNA CTD PMID:15980968 NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708
JBrowse link
G Stam signal transducing adaptor molecule decreases expression ISO Carmustine results in decreased expression of STAM mRNA CTD PMID:15980968 NCBI chr17:77,120,235...77,166,173
Ensembl chr17:77,120,158...77,166,467
JBrowse link
G Stc1 stanniocalcin 1 affects response to substance ISO STC1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
JBrowse link
G Stmn1 stathmin 1 affects response to substance ISO STMN1 mRNA affects the susceptibility to Carmustine CTD PMID:17440165 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Sts steroid sulfatase increases expression ISO Carmustine results in increased expression of STS mRNA CTD PMID:15980968 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402
JBrowse link
G Stx1b syntaxin 1B decreases expression ISO Carmustine results in decreased expression of STX1B mRNA CTD PMID:15980968 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280
JBrowse link
G Stxbp2 syntaxin binding protein 2 decreases expression ISO Carmustine results in decreased expression of STXBP2 mRNA CTD PMID:15980968 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
JBrowse link
G Stxbp6 syntaxin binding protein 6 affects response to substance ISO STXBP6 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:61,920,756...62,157,405
Ensembl chr 6:61,920,756...62,158,024
JBrowse link
G Synpo2 synaptopodin 2 affects response to substance ISO SYNPO2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:211,217,099...211,371,267
Ensembl chr 2:211,216,783...211,371,267
JBrowse link
G Syp synaptophysin multiple interactions
decreases expression
EXP Melatonin inhibits the reaction [Carmustine results in decreased expression of SYP protein] CTD PMID:17572393 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Tac1 tachykinin, precursor 1 decreases expression ISO Carmustine results in decreased expression of TAC1 mRNA CTD PMID:15980968 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tagln transgelin affects response to substance ISO TAGLN mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tbx3 T-box transcription factor 3 affects response to substance ISO TBX3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tcf21 transcription factor 21 decreases expression ISO Carmustine results in decreased expression of TCF21 mRNA CTD PMID:15980968 NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202
JBrowse link
G Tcim transcriptional and immune response regulator increases response to substance ISO TCIM mRNA results in increased susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581
JBrowse link
G Tdrp testis development related protein affects response to substance ISO TDRP mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:75,624,047...75,652,635
Ensembl chr16:75,624,907...75,652,420
JBrowse link
G Tert telomerase reverse transcriptase decreases response to substance ISO TERT protein mutant form results in decreased susceptibility to Carmustine CTD PMID:12488552 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tfap2c transcription factor AP-2 gamma affects response to substance ISO TFAP2C mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
JBrowse link
G Tfdp1 transcription factor Dp-1 affects response to substance ISO TFDP1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 affects response to substance ISO TFPI2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
EXP Melatonin inhibits the reaction [Carmustine results in decreased expression of TGFB1 protein] CTD PMID:17572393 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase increases activity
increases expression
EXP Carmustine results in increased activity of TH protein
Carmustine results in increased expression of TH mRNA; Carmustine results in increased expression of TH protein
CTD PMID:14670008 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thbd thrombomodulin affects response to substance ISO THBD mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Tle3 TLE family member 3, transcriptional corepressor decreases expression ISO Carmustine results in decreased expression of TLE3 mRNA CTD PMID:15980968 NCBI chr 8:61,857,791...61,903,505
Ensembl chr 8:61,858,200...61,903,493
JBrowse link
G Tmem158 transmembrane protein 158 affects response to substance ISO TMEM158 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:122,913,675...122,914,673
Ensembl chr 8:122,913,675...122,914,673
JBrowse link
G Tmem19 transmembrane protein 19 affects response to substance ISO TMEM19 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:50,958,887...51,007,974
Ensembl chr 7:50,958,888...50,986,809
Ensembl chr 7:50,958,888...50,986,809
JBrowse link
G Tmprss15 transmembrane serine protease 15 affects response to substance ISO TMPRSS15 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr11:17,677,741...17,802,255
Ensembl chr11:17,677,741...17,802,255
JBrowse link
G Tnc tenascin C affects response to substance ISO TNC mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP
ISO
[Carmustine co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitrites]; [Carmustine co-treated with Buthionine Sulfoximine] inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Buthionine Sulfoximine promotes the reaction [Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]]; Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; Carmustine promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; MT2 protein inhibits the reaction [Carmustine results in increased expression of TNF protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Carmustine]; Zinc Sulfate inhibits the reaction [Carmustine results in increased expression of TNF protein]
Carmustine promotes the reaction [Oligodeoxyribonucleotides analog results in increased secretion of TNF protein]
CTD PMID:7532384 PMID:11970852 PMID:12433058 PMID:12477282 PMID:18528683 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases response to substance ISO TNFAIP3 mRNA results in increased susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression ISO Carmustine results in decreased expression of TNFRSF11B mRNA CTD PMID:15980968 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 affects response to substance ISO TNFRSF19 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795
JBrowse link
G Tnfsf10 TNF superfamily member 10 affects response to substance ISO TNFSF10 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
increases response to substance
decreases response to substance
affects response to substance
ISO [Carmustine co-treated with O(6)-benzylguanine] results in increased expression of TP53 protein; MDM4 protein promotes the reaction [Carmustine results in increased expression of TP53 protein]
TP53 results in increased susceptibility to Carmustine
TP53 protein results in decreased susceptibility to Carmustine
TP53 protein modified form affects the susceptibility to Carmustine
CTD PMID:10455409 PMID:11861384 PMID:15735757 PMID:16193384 PMID:18632648 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpd52l1 TPD52 like 1 affects response to substance ISO TPD52L1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Traf1 TNF receptor-associated factor 1 decreases expression ISO Carmustine results in decreased expression of TRAF1 mRNA CTD PMID:15980968 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807
JBrowse link
G Trex1 three prime repair exonuclease 1 increases expression ISO Carmustine results in increased expression of TREX1 mRNA CTD PMID:23578789 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
JBrowse link
G Trim50 tripartite motif-containing 50 affects response to substance ISO TRIM50 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:21,300,784...21,317,668
Ensembl chr12:21,300,785...21,317,668
JBrowse link
G Tspan4 tetraspanin 4 decreases expression ISO Carmustine results in decreased expression of TSPAN4 mRNA CTD PMID:15980968 NCBI chr 1:196,571,307...196,593,842
Ensembl chr 1:196,572,228...196,617,448
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression ISO Carmustine results in increased expression of TUBB mRNA CTD PMID:15980968 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tubg1 tubulin, gamma 1 decreases expression ISO Carmustine results in decreased expression of TUBG1 mRNA CTD PMID:15980968 NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,052,743...86,059,433
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial affects response to substance ISO TUFM mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395
JBrowse link
G Tulp3 TUB like protein 3 affects response to substance ISO TULP3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:161,590,478...161,632,514
Ensembl chr 4:161,590,479...161,632,149
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions
decreases activity
EXP [Carmustine co-treated with Buthionine Sulfoximine] results in decreased activity of TXNRD1 protein
Carmustine results in decreased activity of TXNRD1 protein
CTD PMID:16085187 PMID:16288907 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ugt8 UDP glycosyltransferase 8 increases expression ISO Carmustine results in increased expression of UGT8 mRNA CTD PMID:15980968 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660
JBrowse link
G Upf1 UPF1, RNA helicase and ATPase decreases expression ISO Carmustine results in decreased expression of UPF1 mRNA CTD PMID:15980968 NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568
JBrowse link
G Vamp4 vesicle-associated membrane protein 4 affects response to substance ISO VAMP4 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr13:74,919,872...74,942,791
Ensembl chr13:74,919,880...74,933,686
JBrowse link
G Vat1l vesicle amine transport 1-like affects response to substance ISO VAT1L mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:42,194,481...42,363,835
Ensembl chr19:42,194,533...42,363,831
JBrowse link
G Vgf VGF nerve growth factor inducible decreases expression ISO Carmustine results in decreased expression of VGF mRNA CTD PMID:15980968 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341
JBrowse link
G Vldlr very low density lipoprotein receptor affects response to substance ISO VLDLR mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Wasf2 WASP family member 2 affects response to substance ISO WASF2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:145,336,816...145,402,041
Ensembl chr 5:145,336,842...145,399,242
JBrowse link
G Wfdc1 WAP four-disulfide core domain 1 affects response to substance ISO WFDC1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:47,720,191...47,739,121
Ensembl chr19:47,720,423...47,739,108
JBrowse link
G Wipf1 WAS/WASL interacting protein family, member 1 decreases expression ISO Carmustine results in decreased expression of WIPF1 mRNA CTD PMID:15980968 NCBI chr 3:58,314,521...58,416,668
Ensembl chr 3:58,314,542...58,372,742
JBrowse link
G Wnt5a Wnt family member 5A affects response to substance ISO WNT5A mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Wt1 WT1 transcription factor decreases response to substance ISO WT1 results in decreased susceptibility to Carmustine CTD PMID:20820871 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta decreases expression ISO Carmustine results in decreased expression of YWHAH mRNA CTD PMID:15980968 NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
JBrowse link
G Zbtb17 zinc finger and BTB domain containing 17 decreases expression ISO Carmustine results in decreased expression of ZBTB17 mRNA CTD PMID:15980968 NCBI chr 5:153,753,508...153,774,613
Ensembl chr 5:153,753,569...153,774,609
JBrowse link
G Zc3h13 zinc finger CCCH type containing 13 affects response to substance ISO ZC3H13 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr15:50,607,335...50,671,802
Ensembl chr15:50,607,380...50,671,802
JBrowse link
G Zfp112 zinc finger protein 112 affects response to substance ISO ZNF112 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:79,676,933...79,691,994
Ensembl chr 1:79,676,839...79,691,994
JBrowse link
G Zfp189 zinc finger protein 189 increases expression EXP Carmustine results in increased expression of ZNF189 mRNA CTD PMID:16005536 NCBI chr 5:63,872,596...63,884,348
Ensembl chr 5:63,872,738...63,884,121
JBrowse link
G Zfp655 zinc finger protein 655 affects response to substance ISO ZNF655 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:9,349,985...9,375,449
Ensembl chr12:9,357,639...9,374,569
JBrowse link
G Zyx zyxin decreases expression ISO Carmustine results in decreased expression of ZYX mRNA CTD PMID:15980968 NCBI chr 4:71,236,767...71,246,553
Ensembl chr 4:71,237,451...71,246,553
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        pharmaceutical 19329
          drug 19329
            antineoplastic agent 17317
              carmustine 469
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        carboacyl group 17485
                                          univalent carboacyl group 17485
                                            carbamoyl group 17299
                                              carboxamide 17299
                                                monocarboxylic acid amide 15008
                                                  urea 5110
                                                    ureas 5108
                                                      N-nitrosoureas 2039
                                                        carmustine 469
paths to the root