Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:carisoprodol
go back to main search page
Accession:CHEBI:3419 term browser browse the term
Definition:A carbamate ester that is the mono-N-isopropyl derivative of meprobamate (which is a significant metabolite). Carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alteration in pain perception. It is used as a muscle relaxant in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.
Synonyms:exact_synonym: 2-[(carbamoyloxy)methyl]-2-methylpentyl propan-2-ylcarbamate
 related_synonym: (1-methylethyl)carbamic acid 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl ester;   2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate;   2-methyl-2-propyltrimethylene carbamate isopropylcarbamate;   Formula=C12H24N2O4;   InChI=1S/C12H24N2O4/c1-5-6-12(4,7-17-10(13)15)8-18-11(16)14-9(2)3/h9H,5-8H2,1-4H3,(H2,13,15)(H,14,16);   InChIKey=OFZCIYFFPZCNJE-UHFFFAOYSA-N;   N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamate;   SMILES=CCCC(C)(COC(N)=O)COC(=O)NC(C)C;   carbamic acid 2-isopropylcarbamoyloxymethyl-2-methyl-pentyl ester;   carisoprodolum;   isopropyl meprobamate
 alt_id: CHEBI:330249
 xref: Beilstein:1791537 "Beilstein";   CAS:78-44-4 "ChemIDplus";   CAS:78-44-4 "KEGG COMPOUND";   CAS:78-44-4 "NIST Chemistry WebBook";   DrugBank:DB00395;   Drug_Central:509 "DrugCentral";   HMDB:HMDB0014539;   KEGG:C07927;   KEGG:D00768;   LINCS:LSM-5197
 xref_mesh: MESH:D002328
 xref: PMID:14521410 "ChEMBL";   PMID:17725338 "ChEMBL";   Patent:US2937119;   Reaxys:1791537 "Reaxys";   Wikipedia:Carisoprodol


show annotations for term's descendants       view all columns           Sort by:
 
carisoprodol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Gabra1 gamma-aminobutyric acid type A receptor alpha1 subunit JBrowse link 10 27,310,718 27,371,802 RGD:6480464
G Gabrb2 gamma-aminobutyric acid type A receptor beta 2 subunit JBrowse link 10 27,973,694 28,193,072 RGD:6480464
G Gabrg2 gamma-aminobutyric acid type A receptor gamma 2 subunit JBrowse link 10 27,090,913 27,179,786 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        pharmaceutical 19081
          drug 19081
            neuromuscular agent 1282
              muscle relaxant 1277
                carisoprodol 4
                  (R)-carisoprodol 0
                  (S)-carisoprodol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic ester 13946
                                        carbamate ester 7330
                                          carisoprodol 4
                                            (R)-carisoprodol 0
                                            (S)-carisoprodol 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.