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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:19(S)-HETE
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Accession:CHEBI:34185 term browser browse the term
Definition:A HETE having a (19S)-hydroxy group and all-cis double bonds at positions 5, 8, 11 and 14.
Synonyms:related_synonym: (19S)-Hydroxy arachidonic acid;   (19S)-Hydroxyeicosatetraenoic acid;   (19S)-Hydroxyicosatetraenoic acid;   (19S,5Z,8Z,11Z,14Z)-19-hydroxy-5,8,11,14-eicosatetraenoic acid;   (5Z,8Z,11Z,14Z,19S)-19-hydroxyeicosa-5,8,11,14-tetraenoic acid;   (5Z,8Z,11Z,14Z,19S)-19-hydroxyicosa-5,8,11,14-tetraenoic acid;   19(S)-hydroxy-all-cis-5,8,11,14-eicosatetraenoic acid;   19(S)-hydroxyeicosa-5(Z),8(Z),11(Z),14(Z)-tetraenoic acid;   Formula=C20H32O3;   InChI=1S/C20H32O3/c1-19(21)17-15-13-11-9-7-5-3-2-4-6-8-10-12-14-16-18-20(22)23/h3-6,9-12,19,21H,2,7-8,13-18H2,1H3,(H,22,23)/b5-3-,6-4-,11-9-,12-10-/t19-/m0/s1;   InChIKey=XFUXZHQUWPFWPR-DZBJBCEBSA-N;   SMILES=C[C@H](O)CCC\\C=C/C\\C=C/C\\C=C/C\\C=C/CCCC(O)=O
 xref: Beilstein:3059697;   CAS:79551-85-2;   KEGG:C14749;   LIPID_MAPS_instance:LMFA03060074
 xref_mesh: MESH:C055986
 xref: PMID:10836982;   PMID:2837181;   Reaxys:9580694


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19(S)-HETE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects metabolic processing EXP CYP2E1 protein affects the metabolism of 19-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:15205388 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases chemical synthesis ISO CYP4F3 protein alternative form results in increased chemical synthesis of 19-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:30259074 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      atom 19814
        nonmetal atom 19690
          carbon atom 19597
            organic molecular entity 19597
              fatty acid derivative 1021
                icosanoid 453
                  HETE 33
                    19(S)-HETE 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        monocarboxylic acid 17476
                                          fatty acid 15990
                                            unsaturated fatty acid 923
                                              polyunsaturated fatty acid 664
                                                fatty acid 20:4 313
                                                  icosatetraenoic acid 313
                                                    icosa-5,8,11,14-tetraenoic acid 264
                                                      arachidonic acid 264
                                                        19(S)-HETE 2
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