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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:34172 term browser browse the term
Definition:A C19-steroid that is testosterone in which the hydrogen at the 16alpha position has been replaced by a hydroxy group.
Synonyms:related_synonym: (16alpha,17beta)-16,17-dihydroxyandrost-4-en-3-one;   16alpha,17beta-dihydroxyandrost-4-en-3-one;   Formula=C19H28O3;   InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h9,13-17,21-22H,3-8,10H2,1-2H3/t13-,14+,15+,16-,17+,18+,19+/m1/s1;   InChIKey=YMCWOAZGWMZGQT-FPNLOETNSA-N;   SMILES=C1C(C=C2[C@](C1)([C@@]3([C@@](CC2)([C@@]4([H])[C@@](CC3)(C)[C@H]([C@@H](C4)O)O)[H])[H])C)=O
 xref: CAS:63-01-4;   KEGG:C14600
 xref_mesh: MESH:C045261
 xref: PMID:1001810;   PMID:14478807;   PMID:5498128

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16alpha-hydroxytestosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [ABCC1 gene mutant form results in increased hydroxylation of Testosterone] which results in increased chemical synthesis of 16-hydroxytestosterone CTD PMID:22522787 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    chemical entity 19853
      group 19767
        organic group 18550
          3-oxo-Delta(4)-steroid group 7947
            3-oxo-Delta(4) steroid 7947
              16alpha-hydroxytestosterone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic group 18550
                              organic divalent group 18541
                                organodiyl group 18541
                                  carbonyl group 18447
                                    carbonyl compound 18447
                                      ketone 16192
                                        oxo steroid 9293
                                          3-oxo steroid 8819
                                            3-oxo-Delta(4) steroid 7947
                                              testosterone 2849
                                                16alpha-hydroxytestosterone 1
paths to the root