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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:34172 term browser browse the term
Definition:A C19-steroid that is testosterone in which the hydrogen at the 16alpha position has been replaced by a hydroxy group.
Synonyms:related_synonym: (16alpha,17beta)-16,17-dihydroxyandrost-4-en-3-one;   16alpha,17beta-dihydroxyandrost-4-en-3-one;   Formula=C19H28O3;   InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h9,13-17,21-22H,3-8,10H2,1-2H3/t13-,14+,15+,16-,17+,18+,19+/m1/s1;   InChIKey=YMCWOAZGWMZGQT-FPNLOETNSA-N;   SMILES=C1C(C=C2[C@](C1)([C@@]3([C@@](CC2)([C@@]4([H])[C@@](CC3)(C)[C@H]([C@@H](C4)O)O)[H])[H])C)=O
 xref: CAS:63-01-4;   KEGG:C14600
 xref_mesh: MESH:C045261
 xref: PMID:1001810;   PMID:14478807;   PMID:5498128

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16alpha-hydroxytestosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [ABCC1 gene mutant form results in increased hydroxylation of Testosterone] which results in increased chemical synthesis of 16-hydroxytestosterone CTD PMID:22522787 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    chemical entity 20088
      group 19990
        organic group 18988
          3-oxo-Delta(4)-steroid group 9160
            3-oxo-Delta(4) steroid 9160
              16alpha-hydroxytestosterone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  carbonyl group 18903
                                    carbonyl compound 18925
                                      ketone 17115
                                        oxo steroid 10321
                                          3-oxo steroid 9924
                                            3-oxo-Delta(4) steroid 9160
                                              testosterone 4792
                                                16alpha-hydroxytestosterone 1
paths to the root