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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:34172 term browser browse the term
Definition:A C19-steroid that is testosterone in which the hydrogen at the 16alpha position has been replaced by a hydroxy group.
Synonyms:related_synonym: (16alpha,17beta)-16,17-dihydroxyandrost-4-en-3-one;   16alpha,17beta-dihydroxyandrost-4-en-3-one;   Formula=C19H28O3;   InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h9,13-17,21-22H,3-8,10H2,1-2H3/t13-,14+,15+,16-,17+,18+,19+/m1/s1;   InChIKey=YMCWOAZGWMZGQT-FPNLOETNSA-N;   SMILES=C1C(C=C2[C@](C1)([C@@]3([C@@](CC2)([C@@]4([H])[C@@](CC3)(C)[C@H]([C@@H](C4)O)O)[H])[H])C)=O
 xref: CAS:63-01-4;   KEGG:C14600
 xref_mesh: MESH:C045261
 xref: PMID:1001810;   PMID:14478807;   PMID:5498128

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16alpha-hydroxytestosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [ABCC1 gene mutant form results in increased hydroxylation of Testosterone] which results in increased chemical synthesis of 16-hydroxytestosterone CTD PMID:22522787 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      group 19741
        organic group 18737
          3-oxo-Delta(4)-steroid group 8420
            3-oxo-Delta(4) steroid 8420
              16alpha-hydroxytestosterone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      ketone 16923
                                        oxo steroid 9720
                                          3-oxo steroid 9279
                                            3-oxo-Delta(4) steroid 8420
                                              testosterone 3620
                                                16alpha-hydroxytestosterone 1
paths to the root