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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:16-Ketoestrone
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Accession:CHEBI:34166 term browser browse the term
Definition:A 3-hydroxy steroid that has formula C18H20O3.
Synonyms:related_synonym: 3-Hydroxy-1,3,5(10)-estratriene-16,17-dione;   Formula=C18H20O3;   InChI=1S/C18H20O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-15,19H,2,4,6-7,9H2,1H3/t13-,14-,15+,18+/m1/s1;   InChIKey=ANPHVANSJXDRTP-BSXFFOKHSA-N;   SMILES=C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC(=O)C2=O
 xref: CAS:1228-73-5;   KEGG:C14441
 xref_mesh: MESH:C002591


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16-Ketoestrone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction ISO AKR1A1 protein results in increased reduction of 16-ketoestrone CTD PMID:10510318 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases reduction ISO AKR1B1 protein results in increased reduction of 16-ketoestrone CTD PMID:10510318 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of 16-ketoestrone CTD PMID:18845131 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases reduction ISO AKR7A2 protein results in increased reduction of 16-ketoestrone CTD PMID:10510318 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Esr2 estrogen receptor 2 affects binding ISO 16-ketoestrone binds to ESR2 protein CTD PMID:16728493 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      molecular entity 19814
        polyatomic entity 19727
          heteroatomic molecular entity 19653
            hydroxides 19107
              organic hydroxy compound 18661
                hydroxy steroid 12380
                  3-hydroxy steroid 10008
                    16-Ketoestrone 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                organic polycyclic compound 16395
                                  steroid 12800
                                    hydroxy steroid 12380
                                      3-hydroxy steroid 10008
                                        16-Ketoestrone 5
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