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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:34161 term browser browse the term
Definition:An androstanoid that is testosterone substituted by a alpha-hydroxy group at position 15. A natural product found in Daphnia magna exposed to the biocide tributyltin.
Synonyms:related_synonym: 15alpha,17beta-dihydroxyandrost-4-en-3-one;   Formula=C19H28O3;   InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)16(22)10-15(21)17(13)19/h9,13-17,21-22H,3-8,10H2,1-2H3/t13-,14+,15+,16+,17-,18+,19-/m1/s1;   InChIKey=KYGUQDTWUBBBSD-MJVYMRHDSA-N;   SMILES=C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1[C@@H](O)C[C@@H]2O
 alt_id: CHEBI:83028
 xref: CAS:2226-70-2;   KEGG:C14649
 xref_mesh: MESH:C035390
 xref: PMID:9419269;   Reaxys:2419711

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15alpha-hydroxytestosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [[ABCC1 gene mutant form results in increased susceptibility to Testosterone deficiency] which results in decreased hydroxylation of Testosterone] which results in decreased chemical synthesis of 15-hydroxytestosterone CTD PMID:22522787 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    chemical entity 19883
      group 19795
        organic group 18580
          3-oxo-Delta(4)-steroid group 7959
            3-oxo-Delta(4) steroid 7959
              15alpha-hydroxytestosterone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      carbon group element atom 19679
                        carbon atom 19668
                          organic molecular entity 19668
                            organic group 18580
                              organic divalent group 18571
                                organodiyl group 18571
                                  carbonyl group 18479
                                    carbonyl compound 18479
                                      ketone 16222
                                        oxo steroid 9304
                                          3-oxo steroid 8831
                                            3-oxo-Delta(4) steroid 7959
                                              testosterone 2855
                                                15alpha-hydroxytestosterone 1
paths to the root