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ONTOLOGY REPORT - ANNOTATIONS


Term:14,15-EET
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Accession:CHEBI:34157 term browser browse the term
Definition:An EET obtained by formal epoxidation of the 14,15-double bond of arachidonic acid.
Synonyms:exact_synonym: (5Z,8Z,11Z)-13-(3-pentyloxiran-2-yl)trideca-5,8,11-trienoic acid
 related_synonym: (5Z,8Z,11Z)-14,15-Epoxyeicosa-5.8.11-trienoic acid;   (5Z,8Z,11Z)-14,15-Epoxyicosa-5.8.11-trienoic acid;   14,15-EpETrE;   14,15-epoxy-5Z,8Z,11Z-eicosatrienoic acid;   14,15-epoxy-5Z,8Z,11Z-icosatrienoic acid;   Formula=C20H32O3;   InChI=1S/C20H32O3/c1-2-3-12-15-18-19(23-18)16-13-10-8-6-4-5-7-9-11-14-17-20(21)22/h4,6-7,9-10,13,18-19H,2-3,5,8,11-12,14-17H2,1H3,(H,21,22)/b6-4-,9-7-,13-10-;   InChIKey=JBSCUHKPLGKXKH-ILYOTBPNSA-N;   SMILES=CCCCCC1OC1C\\C=C/C\\C=C/C\\C=C/CCCC(O)=O;   all-cis-14,15-epoxyeicosa-5,8,11-trienoic acid
 xref: HMDB:HMDB0004264;   KEGG:C14771;   LIPID_MAPS_instance:LMFA03080005 "LIPID MAPS"
 xref_mesh: MESH:C046782
 xref: PMID:19653681 "Europe PMC";   Reaxys:4703440 "Reaxys"
 cyclic_relationship: is_conjugate_acid_of CHEBI:84024


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14,15-EET term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 JBrowse link 11 105,967,948 105,989,964 RGD:6480464
G Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 JBrowse link X 164,139,342 164,188,418 RGD:6480464
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) JBrowse link 8 124,556,587 124,569,706 RGD:6480464
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6480464
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 JBrowse link 19 39,287,044 39,330,713 RGD:6480464
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 JBrowse link 19 39,061,006 39,093,948 RGD:6480464
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 JBrowse link 19 39,113,898 39,186,756 RGD:6480464
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 JBrowse link 5 145,854,607 145,879,854 RGD:6480464
G Ephx2 epoxide hydrolase 2, cytoplasmic JBrowse link 14 66,084,372 66,124,522 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 3 37,348,477 37,410,106 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Ren2 renin 2 tandem duplication of Ren1 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 JBrowse link 11 86,498,869 86,544,885 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20742
    role 20720
      biological role 20719
        biochemical role 19809
          metabolite 19732
            EET 16
              14,15-EET 15
                (14R,15S)-EET 0
                (14S,15R)-EET 0
                14,15-epoxy-(5Z,8Z,11Z)-icosatrienoyl-CoA 0
                2-glyceryl 14,15-epoxy-(5Z,8Z,11Z)-icosatrienoate 0
                N-[(5Z,8Z,11Z)-14,15-epoxyicosatrienoyl]ethanolamine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20742
    subatomic particle 20735
      composite particle 20735
        hadron 20735
          baryon 20735
            nucleon 20735
              atomic nucleus 20735
                atom 20735
                  main group element atom 20655
                    p-block element atom 20655
                      carbon group element atom 20391
                        carbon atom 20367
                          organic molecular entity 20367
                            organic group 19036
                              organic divalent group 19026
                                organodiyl group 19026
                                  carbonyl group 18997
                                    carbonyl compound 18997
                                      carboxylic acid 18668
                                        monocarboxylic acid 17887
                                          fatty acid 16343
                                            unsaturated fatty acid 899
                                              polyunsaturated fatty acid 653
                                                fatty acid 20:4 315
                                                  icosatetraenoic acid 315
                                                    icosa-5,8,11,14-tetraenoic acid 266
                                                      arachidonic acid 266
                                                        EET 16
                                                          14,15-EET 15
                                                            (14R,15S)-EET 0
                                                            (14S,15R)-EET 0
                                                            14,15-epoxy-(5Z,8Z,11Z)-icosatrienoyl-CoA 0
                                                            2-glyceryl 14,15-epoxy-(5Z,8Z,11Z)-icosatrienoate 0
                                                            N-[(5Z,8Z,11Z)-14,15-epoxyicosatrienoyl]ethanolamine 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.