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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:deoxymannose
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Accession:CHEBI:33983 term browser browse the term
Synonyms:related_synonym: deoxymannoses


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icariside II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
ISO baohuoside I results in decreased phosphorylation of AKT1 protein
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]
CTD PMID:25119583 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt1s1 AKT1 substrate 1 multiple interactions
decreases phosphorylation
ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]
baohuoside I results in decreased phosphorylation of AKT1S1 protein
CTD PMID:25119583 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression EXP baohuoside I results in increased expression of ALPL mRNA CTD PMID:17764702 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO baohuoside I results in increased expression of BAX protein CTD PMID:22687635 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO baohuoside I results in decreased expression of BCL2 protein CTD PMID:22687635 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression EXP baohuoside I results in increased expression of BGLAP mRNA CTD PMID:17764702 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases phosphorylation
multiple interactions
ISO baohuoside I results in decreased phosphorylation of BRAF protein
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of BRAF protein]
CTD PMID:25119583 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Casp3 caspase 3 increases cleavage
increases activity
ISO baohuoside I results in increased cleavage of CASP3 protein
baohuoside I results in increased activity of CASP3 protein
CTD PMID:19289254 PMID:22687635 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO baohuoside I results in increased activity of CASP8 protein CTD PMID:19289254 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity
increases cleavage
ISO baohuoside I results in increased activity of CASP9 protein
baohuoside I results in increased cleavage of CASP9 protein
CTD PMID:19289254 PMID:22687635 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression EXP baohuoside I results in increased expression of COL1A2 mRNA CTD PMID:17764702 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Egf epidermal growth factor multiple interactions ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of BRAF protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MTOR protein] CTD PMID:25119583 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases phosphorylation
ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
baohuoside I results in decreased phosphorylation of EGFR protein
CTD PMID:25119583 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO baohuoside I results in decreased phosphorylation of GSK3B protein CTD PMID:25119583 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]
baohuoside I results in decreased phosphorylation of MAPK1 protein
CTD PMID:25119583 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]
baohuoside I results in decreased phosphorylation of MAPK3 protein
CTD PMID:25119583 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO baohuoside I results in decreased expression of MKI67 protein CTD PMID:25119583 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation
ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MTOR protein]
baohuoside I results in decreased phosphorylation of MTOR protein
CTD PMID:25119583 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO baohuoside I results in decreased expression of NOS2 CTD PMID:19289254 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO baohuoside I results in increased cleavage of PARP1 protein
Dinoprostone inhibits the reaction [baohuoside I results in increased cleavage of PARP1 protein]; PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein]
CTD PMID:19289254 PMID:22687635 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 decreases phosphorylation ISO baohuoside I results in decreased phosphorylation of PDPK1 protein CTD PMID:25119583 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
ISO baohuoside I results in decreased expression of PTGS2
[baohuoside I results in decreased expression of PTGS2] which results in decreased abundance of Dinoprostone; PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein]
CTD PMID:19289254 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression EXP baohuoside I results in increased expression of TNFRSF11B mRNA CTD PMID:17764702 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression EXP baohuoside I results in decreased expression of TNFSF11 mRNA CTD PMID:17764702 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO baohuoside I results in decreased expression of VEGFA CTD PMID:19289254 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
rhamnose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oat ornithine aminotransferase multiple interactions EXP Rhamnose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      atom 19819
        nonmetal atom 19707
          oxygen atom 19445
            oxygen molecular entity 19445
              organooxygen compound 19014
                carbohydrates and carbohydrate derivatives 12341
                  carbohydrate 12341
                    deoxy sugar 128
                      deoxyhexose 128
                        deoxymannose 26
                          deoxymannose derivative + 0
                          rhamnose + 26
                          tyvelose + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            heteroorganic entity 19294
                              organochalcogen compound 19064
                                organooxygen compound 19014
                                  carbohydrates and carbohydrate derivatives 12341
                                    carbohydrate 12341
                                      monosaccharide 4297
                                        aldose 2671
                                          aldohexose 2309
                                            deoxyhexose 128
                                              deoxymannose 26
                                                deoxymannose derivative + 0
                                                rhamnose + 26
                                                tyvelose + 0
paths to the root