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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ribose
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Accession:CHEBI:33942 term browser browse the term
Definition:Any aldopentose where the open-chain form has all the hydroxy groups on the same side in the Fischer projection. Occurrs in two enantiomeric forms, D- and L-ribose, of which only the former is found in nature.
Synonyms:exact_synonym: ribo-pentose
 related_synonym: Formula=C5H10O5;   Rib
 alt_id: CHEBI:26564



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2'-deoxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO [9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein; Deoxycytidine inhibits the reaction [[9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein] CTD PMID:9297556 PMID:9403342 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO CYP1A1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO CYP1A2 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO CYP1B1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP3A4 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity ISO Deoxyguanosine analog results in decreased activity of MGMT protein CTD PMID:17880193 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
2-deoxy-alpha-D-ribose 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tymp thymidine phosphorylase increases abundance ISO TYMP protein results in increased abundance of 2-deoxyribose 1-phosphate CTD PMID:11103787 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
2-deoxy-D-ribofuranose 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tymp thymidine phosphorylase increases abundance ISO TYMP protein results in increased abundance of 2-deoxyribose 1-phosphate CTD PMID:11103787 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
3'-phospho-5'-adenylyl sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nat2 N-acetyltransferase 2 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G P2ry1 purinergic receptor P2Y1 decreases activity ISO Phosphoadenosine Phosphosulfate results in decreased activity of P2RY1 protein CTD PMID:22273509 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions
increases sulfation
ISO 2,2',3,4,4',5',6-heptabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Halogenated Diphenyl Ethers analog inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; pentabrominated diphenyl ether 100 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; Pentachlorophenol inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; tetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; tribromodiphenyl ether 28 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]
SULT1A1 protein results in increased sulfation of Phosphoadenosine Phosphosulfate
CTD PMID:11425650 PMID:16601080 PMID:20545351 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions ISO [Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol; Celecoxib affects the reaction [[Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol]; SULT2A1 protein affects the metabolism of [Phosphoadenosine Phosphosulfate co-treated with Ethinyl Estradiol] CTD PMID:15483193 NCBI chr 1:75,451,178...75,508,142 JBrowse link
3-iodobenzyl-5'-N-methylcarboxamidoadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora3 adenosine A3 receptor multiple interactions EXP
ISO
2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 mRNA]]; 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 protein]]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 mRNA]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 protein]
[N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein] which results in decreased susceptibility to Dizocilpine Maleate; [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein] which results in decreased susceptibility to Scopolamine; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein
CTD PMID:12672554 PMID:15452191 PMID:19966059
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in increased phosphorylation of AKT1 protein]; wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in increased phosphorylation of AKT1 protein] CTD PMID:16116186 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression
decreases response to substance
ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of BIRC3 mRNA
BIRC3 protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine
CTD PMID:16088125 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases response to substance ISO BIRC5 protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine CTD PMID:16088125 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of FOS mRNA] CTD PMID:15452191 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Il12a interleukin 12A multiple interactions ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]; Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]; wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]] CTD PMID:16116186 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B multiple interactions ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]; Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]; Wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]] CTD PMID:16116186 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 decreases response to substance
decreases expression
ISO NAIP protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine
N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of NAIP mRNA
CTD PMID:16088125 NCBI chr 2:31,507,423...31,559,098 JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:15452191 PMID:19966059 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions EXP N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA] CTD PMID:15452191 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Slc9a1 solute carrier family 9 member A1 multiple interactions EXP N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of SLC9A1 protein] CTD PMID:15452191 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
5'-S-methyl-5'-thioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
ISO 5'-methylthioadenosine results in decreased phosphorylation of AKT1 protein
IL7 protein inhibits the reaction [5'-methylthioadenosine results in decreased phosphorylation of AKT1 protein]
CTD PMID:31712395 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO 5'-methylthioadenosine results in decreased expression of COL1A1 mRNA CTD PMID:15983038 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO 5'-methylthioadenosine results in decreased expression of COL1A2 mRNA CTD PMID:15983038 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of 5'-methylthioadenosine
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 5'-methylthioadenosine]
CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ifng interferon gamma multiple interactions
decreases secretion
ISO 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IFNG mRNA]
5'-methylthioadenosine results in decreased secretion of IFNG protein
CTD PMID:17080400 PMID:31712395 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL1B mRNA] CTD PMID:17080400 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions
decreases secretion
ISO 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL2 mRNA]
5'-methylthioadenosine results in decreased secretion of IL2 protein
CTD PMID:17080400 PMID:31712395 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL6 mRNA] CTD PMID:17080400 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il7 interleukin 7 multiple interactions ISO IL7 protein inhibits the reaction [5'-methylthioadenosine results in decreased phosphorylation of AKT1 protein] CTD PMID:31712395 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Ltb lymphotoxin beta multiple interactions ISO 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of LTB mRNA] CTD PMID:17080400 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Mdm4 MDM4 regulator of p53 multiple interactions ISO 5'-methylthioadenosine affects the splicing of and affects the expression of MDM4 mRNA alternative form CTD PMID:31712395 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO 5'-methylthioadenosine results in decreased phosphorylation of MTOR protein CTD PMID:31712395 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO 5'-methylthioadenosine results in decreased phosphorylation of RPS6 protein CTD PMID:31712395 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Tp53 tumor protein p53 increases expression ISO 5'-methylthioadenosine results in increased expression of TP53 protein CTD PMID:31712395 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
5-azacytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] CTD PMID:22841775 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression ISO Azacitidine results in decreased expression of ADAMTS1 mRNA CTD PMID:20823114 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adrb1 adrenoceptor beta 1 affects expression ISO Azacitidine affects the expression of ADRB1 mRNA CTD PMID:19002953 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 affects expression
multiple interactions
ISO Azacitidine affects the expression of ADRB2 mRNA
Azacitidine inhibits the reaction [Particulate Matter results in decreased expression of ADRB2 mRNA]
CTD PMID:19002953 PMID:30986742 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Afp alpha-fetoprotein increases expression ISO Azacitidine results in increased expression of AFP mRNA CTD PMID:27590069 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Aggf1 angiogenic factor with G patch and FHA domains 1 increases expression ISO Azacitidine results in increased expression of AGGF1 mRNA CTD PMID:19194470 NCBI chr 2:26,619,336...26,646,050
Ensembl chr 2:26,619,339...26,645,952
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression
multiple interactions
ISO Azacitidine results in increased expression of AHR mRNA
[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]
CTD PMID:12927368 PMID:17682057 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ak5 adenylate kinase 5 increases expression ISO Azacitidine results in increased expression of AK5 mRNA CTD PMID:20823114 NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:241,397,297...241,581,458
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:22841775 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alad aminolevulinate dehydratase decreases expression ISO Azacitidine results in decreased expression of ALAD mRNA CTD PMID:19194470 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alb albumin decreases expression
increases expression
ISO Azacitidine results in decreased expression of ALB protein
Azacitidine results in increased expression of ALB mRNA
CTD PMID:27590069 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions ISO [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]] CTD PMID:17682057 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Anxa1 annexin A1 decreases expression EXP Azacitidine results in decreased expression of ANXA1 protein CTD PMID:17105402 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G App amyloid beta precursor protein decreases methylation
multiple interactions
ISO Azacitidine results in decreased methylation of APP promoter
Azacitidine results in increased expression of and results in increased cleavage of APP protein; Betaine inhibits the reaction [Azacitidine results in decreased methylation of APP promoter]; Betaine inhibits the reaction [Azacitidine results in increased expression of and results in increased cleavage of APP protein]
CTD PMID:19635394 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp5 aquaporin 5 decreases methylation
increases expression
multiple interactions
ISO Azacitidine results in decreased methylation of AQP5 promoter
Azacitidine results in increased expression of AQP5 protein
[Azacitidine results in decreased methylation of AQP5 promoter] which results in increased expression of AQP5 mRNA; Azacitidine promotes the reaction [SP1 protein binds to AQP5 promoter]
CTD PMID:17198683 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
JBrowse link
G Aqp9 aquaporin 9 multiple interactions
increases expression
ISO [Azacitidine results in increased expression of AQP9 mRNA] which results in increased uptake of arsenic trioxide; HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA] CTD PMID:25953102 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Ar androgen receptor multiple interactions
increases expression
ISO [Azacitidine analog results in increased expression of AR protein] which results in increased susceptibility to bicalutamide; [Azacitidine analog results in increased expression of AR protein] which results in increased susceptibility to Dihydrotestosterone CTD PMID:18324645 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgap35 Rho GTPase activating protein 35 increases expression ISO Azacitidine results in increased expression of ARHGAP35 mRNA CTD PMID:20823114 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression ISO Azacitidine results in decreased expression of ARHGEF2 mRNA CTD PMID:20823114 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Art1 ADP-ribosyltransferase 1 increases expression ISO Azacitidine results in increased expression of ART1 mRNA CTD PMID:20823114 NCBI chr 1:156,478,096...156,487,172
Ensembl chr 1:156,482,621...156,487,172
JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 increases expression ISO Azacitidine results in increased expression of ASB2 mRNA CTD PMID:20823114 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Azacitidine results in decreased expression of ATP2B1 mRNA CTD PMID:20823114 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C increases expression ISO Azacitidine results in increased expression of ATP6V0C mRNA CTD PMID:20823114 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
JBrowse link
G Aurka aurora kinase A multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of AURKA mRNA CTD PMID:18720364 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
multiple interactions
EXP Azacitidine results in increased expression of BAD mRNA
[Azacitidine co-treated with entinostat] results in increased expression of BAD mRNA
CTD PMID:21224363 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
EXP [Azacitidine co-treated with entinostat] results in increased expression of BAK1 mRNA
Azacitidine results in increased expression of BAK1 mRNA
CTD PMID:21224363 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA] CTD PMID:32278510 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 decreases expression ISO Azacitidine results in decreased expression of BCAT1 mRNA CTD PMID:20823114 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]
Azacitidine results in decreased expression of BCL2 mRNA; Azacitidine results in decreased expression of BCL2 protein
CTD PMID:32278510 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
affects expression
ISO [metacept-1 co-treated with Azacitidine] results in decreased expression of BCL2L1
[Azacitidine affects the expression of IL6R protein] which affects the expression of BCL2L1 protein
CTD PMID:18443271 PMID:19148494 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l13 BCL2 like 13 increases expression ISO Azacitidine results in increased expression of BCL2L13 mRNA CTD PMID:20823114 NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:154,056,127...154,108,985
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression
decreases methylation
multiple interactions
ISO Azacitidine results in increased expression of BDNF mRNA
Azacitidine results in decreased methylation of BDNF promoter
Tetrodotoxin inhibits the reaction [Azacitidine results in decreased methylation of BDNF promoter]; Tetrodotoxin inhibits the reaction [Azacitidine results in increased expression of BDNF mRNA]
CTD PMID:18184782 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression EXP Azacitidine results in decreased expression of BGLAP protein CTD PMID:18037191 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bicd1 BICD cargo adaptor 1 decreases expression ISO Azacitidine results in decreased expression of BICD1 mRNA CTD PMID:20823114 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434
JBrowse link
G Bik BCL2-interacting killer multiple interactions
increases expression
EXP [Azacitidine co-treated with entinostat] results in increased expression of BIK mRNA
Azacitidine results in increased expression of BIK mRNA
CTD PMID:21224363 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Bmp15 bone morphogenetic protein 15 increases expression ISO Azacitidine results in increased expression of BMP15 mRNA CTD PMID:23395740 NCBI chr  X:16,169,123...16,174,187
Ensembl chr  X:16,169,123...16,174,187
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Azacitidine results in increased expression of BNIP3 mRNA CTD PMID:25446377 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bok BCL2 family apoptosis regulator BOK multiple interactions
increases expression
EXP [Azacitidine co-treated with entinostat] results in increased expression of BOK mRNA
Azacitidine results in increased expression of BOK mRNA
CTD PMID:21224363 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of BUB1B mRNA CTD PMID:18720364 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G C3ar1 complement C3a receptor 1 increases expression ISO Azacitidine results in increased expression of C3AR1 mRNA CTD PMID:19194470 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701
JBrowse link
G Calca calcitonin-related polypeptide alpha decreases methylation ISO Azacitidine results in decreased methylation of CALCA promoter CTD PMID:19299654 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cald1 caldesmon 1 increases expression ISO Azacitidine results in increased expression of CALD1 mRNA CTD PMID:20823114 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Casp3 caspase 3 affects expression
increases expression
multiple interactions
ISO Azacitidine affects the expression of CASP3 protein
Azacitidine results in increased expression of CASP3 mRNA
[metacept-1 co-treated with Azacitidine] results in increased expression of CASP3
CTD PMID:18443271 PMID:19148494 PMID:23395740 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases expression ISO Azacitidine results in increased expression of CASP8 mRNA CTD PMID:18082045 PMID:23395740 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression ISO Azacitidine results in increased expression of CASP9 mRNA CTD PMID:23395740 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccna1 cyclin A1 multiple interactions
decreases expression
ISO Azacitidine inhibits the reaction [MECP2 protein binds to CCNA1 promoter]; Azacitidine promotes the reaction [H3-4 protein modified form binds to CCNA1 promoter]; Azacitidine promotes the reaction [H4-16 protein modified form binds to CCNA1 promoter]
Azacitidine results in decreased expression of CCNA1 mRNA
CTD PMID:17698632 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [Azacitidine co-treated with Thalidomide] affects the expression of CCNA2 mRNA
Azacitidine results in decreased expression of CCNA2 mRNA
CTD PMID:18720364 PMID:20823114 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 multiple interactions
increases expression
ISO [Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNA
Azacitidine results in increased expression of CCNB1 protein
CTD PMID:18720364 PMID:20607034 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Azacitidine results in increased expression of CCND1 mRNA CTD PMID:20823114 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 affects methylation
multiple interactions
ISO Azacitidine affects the methylation of CCND2 promoter
[Azacitidine affects the methylation of CCND2 promoter] which affects the expression of CCND2 mRNA
CTD PMID:17016690 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccng2 cyclin G2 decreases expression ISO Azacitidine results in decreased expression of CCNG2 mRNA CTD PMID:21245298 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Cd274 CD274 molecule multiple interactions ISO Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 mRNA]]; Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 protein]] CTD PMID:32894642 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CDC20 mRNA CTD PMID:18720364 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc42bpa CDC42 binding protein kinase alpha decreases expression ISO Azacitidine results in decreased expression of CDC42BPA mRNA CTD PMID:20823114 NCBI chr13:91,683,775...91,903,732
Ensembl chr13:91,684,007...91,903,732
JBrowse link
G Cdh1 cadherin 1 decreases methylation
increases expression
ISO Azacitidine results in decreased methylation of CDH1 promoter
Azacitidine results in increased expression of CDH1 mRNA
CTD PMID:17520682 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 increases expression EXP Azacitidine results in increased expression of CDH2 mRNA CTD PMID:18037191 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
increases expression
ISO [Azacitidine co-treated with Thalidomide] affects the expression of CDK1 mRNA
Azacitidine analog results in increased expression of CDK1 protein
CTD PMID:18324645 PMID:18720364 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Azacitidine analog results in decreased expression of CDK2 protein CTD PMID:18324645 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Azacitidine analog results in decreased expression of CDK4 protein CTD PMID:18324645 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO
EXP
Azacitidine analog results in increased expression of CDKN1A protein; Azacitidine results in increased expression of CDKN1A mRNA
[Azacitidine co-treated with entinostat] results in increased expression of CDKN1A mRNA; Azacitidine inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]
[metacept-1 co-treated with Azacitidine] results in increased expression of CDKN1A
CTD PMID:18324645 PMID:19148494 PMID:20823114 PMID:21224363 PMID:25015661 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO Azacitidine results in increased expression of CDKN1C mRNA CTD PMID:19194470 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
decreases methylation
affects methylation
increases expression
EXP
ISO
[Azacitidine co-treated with entinostat] results in decreased methylation of CDKN2A gene; [Azacitidine co-treated with entinostat] results in increased expression of CDKN2A mRNA
Azacitidine inhibits the reaction [Particulate Matter results in increased methylation of CDKN2A promoter]
Hydroxyurea inhibits the reaction [Azacitidine results in decreased methylation of CDKN2A gene]
Azacitidine affects the methylation of CDKN2A gene
Azacitidine results in increased expression of CDKN2A mRNA
CTD PMID:17686055 PMID:18443271 PMID:21224363 PMID:22355787 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B decreases methylation
multiple interactions
affects response to substance
ISO Azacitidine results in decreased methylation of CDKN2B promoter
[metacept-1 co-treated with Azacitidine] results in increased expression of CDKN2B
CDKN2B promoter modified form affects the susceptibility to Azacitidine
CTD PMID:17611569 PMID:19148494 PMID:19194470 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases methylation
increases expression
ISO Azacitidine results in decreased methylation of CEBPA promoter
Azacitidine results in increased expression of CEBPA mRNA
CTD PMID:19194470 PMID:27590069 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cenpa centromere protein A multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CENPA mRNA CTD PMID:18720364 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cenpf centromere protein F multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CENPF mRNA CTD PMID:18720364 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cenpo centromere protein O increases expression ISO Azacitidine results in increased expression of CENPO mRNA CTD PMID:19194470 NCBI chr 6:27,203,642...27,218,394
Ensembl chr 6:27,188,537...27,218,314
JBrowse link
G Chat choline O-acetyltransferase increases expression ISO Azacitidine results in increased expression of CHAT mRNA; Azacitidine results in increased expression of CHAT protein CTD PMID:19151599 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chga chromogranin A decreases expression ISO Azacitidine results in decreased expression of CHGA protein CTD PMID:20607034 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Chit1 chitinase 1 increases expression ISO Azacitidine results in increased expression of CHIT1 mRNA CTD PMID:20823114 NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 affects expression ISO Azacitidine affects the expression of CHRM1 mRNA CTD PMID:19002953 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 affects expression ISO Azacitidine affects the expression of CHRM2 mRNA CTD PMID:19002953 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chst14 carbohydrate sulfotransferase 14 increases expression EXP Azacitidine results in increased expression of CHST14 mRNA CTD PMID:27415467 NCBI chr 3:105,916,481...105,918,538
Ensembl chr 3:105,916,466...105,918,548
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator multiple interactions
increases expression
ISO [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein; [Azacitidine results in decreased methylation of CIITA promoter] promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]
Azacitidine results in increased expression of CIITA mRNA
CTD PMID:18829986 PMID:20823114 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Cldn10 claudin 10 decreases expression ISO Azacitidine results in decreased expression of CLDN10 mRNA CTD PMID:19194470 NCBI chr15:95,862,785...95,954,526
Ensembl chr15:95,862,760...95,954,526
JBrowse link
G Cldn6 claudin 6 increases expression
decreases methylation
multiple interactions
ISO Azacitidine results in increased expression of CLDN6 mRNA
Azacitidine results in decreased methylation of CLDN6 promoter
[trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN6 promoter
CTD PMID:18661270 NCBI chr10:12,710,302...12,713,987 JBrowse link
G Cldn8 claudin 8 increases expression ISO Azacitidine results in increased expression of CLDN8 mRNA CTD PMID:18661270 NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513
JBrowse link
G Cldn9 claudin 9 decreases methylation
multiple interactions
increases expression
ISO Azacitidine results in decreased methylation of CLDN9 promoter
[trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN9 promoter
Azacitidine results in increased expression of CLDN9 mRNA
CTD PMID:18661270 NCBI chr10:12,714,137...12,715,568 JBrowse link
G Cnnm2 cyclin and CBS domain divalent metal cation transport mediator 2 decreases expression ISO Azacitidine results in decreased expression of CNNM2 mRNA CTD PMID:19194470 NCBI chr 1:245,643,682...245,769,542
Ensembl chr 1:245,643,768...245,763,286
JBrowse link
G Col14a1 collagen type XIV alpha 1 chain increases expression ISO Azacitidine results in increased expression of COL14A1 mRNA CTD PMID:19194470 NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein] CTD PMID:22841775 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col6a3 collagen type VI alpha 3 chain decreases expression ISO Azacitidine results in decreased expression of COL6A3 mRNA CTD PMID:20823114 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471
JBrowse link
G Col9a3 collagen type IX alpha 3 chain decreases expression ISO Azacitidine results in decreased expression of COL9A3 mRNA CTD PMID:18033690 NCBI chr 3:167,711,776...167,734,468
Ensembl chr 3:167,711,840...167,734,465
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression ISO Azacitidine results in increased expression of COX6A2 mRNA CTD PMID:20823114 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Cpe carboxypeptidase E increases expression ISO Azacitidine results in increased expression of CPE mRNA CTD PMID:20823114 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
JBrowse link
G Cplx1 complexin 1 increases expression ISO Azacitidine results in increased expression of CPLX1 mRNA CTD PMID:20823114 NCBI chr14:1,184,638...1,216,392 JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Azacitidine promotes the reaction [CREB1 protein modified form binds to PPP2CA promoter] CTD PMID:19155497 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 increases expression EXP Azacitidine results in increased expression of CREB3L4 mRNA CTD PMID:27415467 NCBI chr 2:175,690,340...175,696,084
Ensembl chr 2:175,690,335...175,695,932
JBrowse link
G Crem cAMP responsive element modulator decreases expression ISO Azacitidine results in decreased expression of CREM mRNA CTD PMID:20823114 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Cryaa crystallin, alpha A increases expression EXP Azacitidine results in increased expression of CRYAA protein CTD PMID:17105402 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349
JBrowse link
G Cryab crystallin, alpha B increases expression EXP Azacitidine results in increased expression of CRYAB protein CTD PMID:17105402 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Csf1 colony stimulating factor 1 increases expression EXP Azacitidine results in increased expression of CSF1 mRNA CTD PMID:17156202 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csn1s1 casein alpha s1 increases expression ISO Azacitidine results in increased expression of CSN1S1 mRNA CTD PMID:20823114 NCBI chr14:20,343,620...20,359,614
Ensembl chr14:20,343,619...20,359,614
JBrowse link
G Cst3 cystatin C increases expression ISO Azacitidine results in increased expression of CST3 mRNA CTD PMID:20823114 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases methylation
increases expression
ISO Azacitidine results in decreased methylation of CXCL12 promoter
Azacitidine results in increased expression of CXCL12 mRNA; Azacitidine results in increased expression of CXCL12 protein
CTD PMID:19748759 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]
Azacitidine results in increased expression of CYP1A1 mRNA
CTD PMID:11281733 PMID:12927368 PMID:17682057 PMID:27590069 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]
Azacitidine results in increased expression of CYP1A2 mRNA
CTD PMID:12927368 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
Azacitidine results in increased expression of CYP1B1 mRNA
CTD PMID:12927368 PMID:27590069 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Azacitidine results in increased expression of CYP3A4 mRNA CTD PMID:27590069 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyth1 cytohesin 1 increases expression ISO Azacitidine results in increased expression of CYTH1 mRNA CTD PMID:19194470 NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760
JBrowse link
G Dapk1 death associated protein kinase 1 affects methylation ISO Azacitidine affects the methylation of DAPK1 promoter CTD PMID:17557868 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Dcn decorin multiple interactions
decreases expression
ISO Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein]
Azacitidine results in decreased expression of DCN mRNA
CTD PMID:20823114 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Des desmin increases expression
multiple interactions
EXP
ISO
Azacitidine results in increased expression of DES mRNA; Azacitidine results in increased expression of DES protein
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA
CTD PMID:18037191 PMID:20823114 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Dhx9 DExH-box helicase 9 decreases expression ISO Azacitidine results in decreased expression of DHX9 mRNA CTD PMID:20823114 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases expression ISO Azacitidine results in decreased expression of DIO2 mRNA CTD PMID:20823114 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases methylation ISO Azacitidine results in decreased methylation of DLK1 promoter CTD PMID:19194470 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
JBrowse link
G Dlx5 distal-less homeobox 5 increases expression ISO Azacitidine results in increased expression of DLX5 mRNA CTD PMID:17085970 NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407
JBrowse link
G Dlx6 distal-less homeobox 6 increases expression ISO Azacitidine results in increased expression of DLX6 mRNA CTD PMID:20823114 NCBI chr 4:34,984,264...34,989,926 JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases expression
ISO
EXP
[SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein; Arsenic Trioxide promotes the reaction [Azacitidine results in decreased expression of DNMT1 protein]
[Azacitidine co-treated with entinostat] results in decreased expression of DNMT1 protein; [Cisplatin co-treated with Azacitidine] results in decreased expression of DNMT1 protein
CTD PMID:19139132 PMID:19723570 PMID:21224363 PMID:28901456 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases methylation
multiple interactions
decreases response to substance
ISO Azacitidine results in decreased methylation of DPYD promoter
[Azacitidine results in decreased methylation of DPYD promoter] which results in increased expression of DPYD mRNA
DPYD protein results in decreased susceptibility to Azacitidine
CTD PMID:15501990 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Azacitidine results in increased expression of DUSP1 mRNA CTD PMID:20823114 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO Azacitidine results in increased expression of DUSP6 mRNA CTD PMID:21245298 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA] CTD PMID:19451745 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression ISO Azacitidine results in decreased expression of EEF1A1 mRNA CTD PMID:20823114 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Efna3 ephrin A3 increases expression ISO Azacitidine results in increased expression of EFNA3 mRNA CTD PMID:20823114 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
JBrowse link
G Egr2 early growth response 2 increases expression ISO Azacitidine results in increased expression of EGR2 mRNA CTD PMID:20823114 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Eno2 enolase 2 decreases expression ISO Azacitidine results in decreased expression of ENO2 protein CTD PMID:20607034 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression ISO Azacitidine results in increased expression of ENTPD1 mRNA CTD PMID:20823114 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO Azacitidine results in increased expression of ESR1 protein CTD PMID:22558281 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions ISO Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL4 promoter] CTD PMID:18945643 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO Azacitidine results in decreased expression of EYA1 mRNA CTD PMID:20823114 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Azacitidine results in decreased expression of FADS2 mRNA CTD PMID:20823114 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fam8a1 family with sequence similarity 8, member A1 increases expression ISO Azacitidine results in increased expression of FAM8A1 mRNA CTD PMID:19194470 NCBI chr17:18,026,601...18,035,509
Ensembl chr17:18,026,601...18,035,470
JBrowse link
G Faslg Fas ligand increases response to substance ISO Azacitidine results in increased susceptibility to FASLG protein CTD PMID:18829727 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fbln1 fibulin 1 increases expression ISO Azacitidine results in increased expression of FBLN1 mRNA CTD PMID:21245298 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
JBrowse link
G Fen1 flap structure-specific endonuclease 1 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of FEN1 mRNA CTD PMID:18720364 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
JBrowse link
G Fgf7 fibroblast growth factor 7 decreases expression ISO Azacitidine results in decreased expression of FGF7 mRNA CTD PMID:20823114 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
JBrowse link
G Filip1l filamin A interacting protein 1-like decreases expression ISO Azacitidine results in decreased expression of FILIP1L mRNA CTD PMID:20823114 NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of FOXO1 mRNA CTD PMID:20823114 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [Azacitidine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein; [Azacitidine results in decreased methylation of FOXP3 gene] which results in increased expression of FOXP3 protein CTD PMID:18493985 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression EXP Azacitidine results in decreased expression of FTL1 protein CTD PMID:17105402 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO Azacitidine results in increased expression of FYN mRNA CTD PMID:21245298 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression ISO Azacitidine results in increased expression of GABRB1 mRNA CTD PMID:19194470 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases methylation
multiple interactions
increases expression
ISO Azacitidine results in decreased methylation of GADD45A promoter
[Azacitidine results in increased expression of GADD45A protein] which results in increased susceptibility to docetaxel
Azacitidine results in increased expression of GADD45A mRNA; Azacitidine results in increased expression of GADD45A protein
CTD PMID:19190346 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions ISO Azacitidine promotes the reaction [Depsipeptides results in increased expression of GADD45B] CTD PMID:18225533 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gata4 GATA binding protein 4 increases expression EXP Azacitidine results in increased expression of GATA4 mRNA; Azacitidine results in increased expression of GATA4 protein CTD PMID:18037191 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO Azacitidine results in decreased expression of GBP2 mRNA CTD PMID:20823114 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) decreases expression ISO Azacitidine results in decreased expression of GCNT2 mRNA CTD PMID:20823114 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO Azacitidine results in increased expression of GDF9 mRNA CTD PMID:23395740 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
decreases expression
EXP
ISO
Azacitidine results in increased expression of GJA1 protein
Azacitidine results in decreased expression of GJA1 mRNA
CTD PMID:18037191 PMID:20823114 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gng7 G protein subunit gamma 7 affects methylation ISO Azacitidine affects the methylation of GNG7 promoter CTD PMID:18219292 NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240
JBrowse link
G Gpkow G patch domain and KOW motifs increases expression ISO Azacitidine results in increased expression of GPKOW mRNA CTD PMID:20823114 NCBI chr  X:14,791,601...14,806,384
Ensembl chr  X:14,791,610...14,806,384
JBrowse link
G Gpnmb glycoprotein nmb decreases expression ISO Azacitidine results in decreased expression of GPNMB mRNA CTD PMID:20823114 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases methylation ISO Azacitidine results in decreased methylation of GRIN2B gene CTD PMID:18618247 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Guk1 guanylate kinase 1 increases expression ISO Azacitidine results in increased expression of GUK1 mRNA CTD PMID:20823114 NCBI chr10:43,971,514...43,988,658
Ensembl chr10:43,971,509...43,980,107
JBrowse link
G Gzmb granzyme B multiple interactions ISO Azacitidine inhibits the reaction [IL2 protein results in increased secretion of GZMB protein] CTD PMID:19394699 NCBI chr15:30,343,361...30,346,792 JBrowse link
G H1f0 H1.0 linker histone increases expression ISO Azacitidine results in increased expression of H1-0 protein CTD PMID:16006241 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
JBrowse link
G H2ax H2A.X variant histone increases expression
multiple interactions
ISO
EXP
Azacitidine results in increased expression of H2AX protein
Azacitidine inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]
CTD PMID:17991895 PMID:25015661 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H3f4 H3.4 histone multiple interactions ISO Azacitidine promotes the reaction [H3-4 protein modified form binds to CCNA1 promoter] CTD PMID:17698632 NCBI chr10:43,740,797...43,741,207 JBrowse link
G H4f16 H4 histone 16 multiple interactions ISO Azacitidine promotes the reaction [H4-16 protein modified form binds to CCNA1 promoter] CTD PMID:17698632
G Hgd homogentisate 1, 2-dioxygenase increases expression ISO Azacitidine results in increased expression of HGD mRNA CTD PMID:20823114 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
JBrowse link
G Hgf hepatocyte growth factor increases expression ISO Azacitidine results in increased expression of HGF mRNA CTD PMID:19194470 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hhex hematopoietically expressed homeobox increases expression ISO Azacitidine results in increased expression of HHEX mRNA CTD PMID:27590069 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression ISO Azacitidine results in increased expression of HMGA1 mRNA CTD PMID:20823114 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression
multiple interactions
ISO Azacitidine results in increased expression of HMGA2 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]
CTD PMID:21245298 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hmgb1 high mobility group box 1 decreases expression
multiple interactions
ISO Azacitidine results in decreased expression of HMGB1 mRNA
Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA]
CTD PMID:32278510 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hnf1a HNF1 homeobox A decreases methylation
multiple interactions
increases expression
ISO Azacitidine results in decreased methylation of HNF1A promoter
HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA]
Azacitidine results in increased expression of HNF1A mRNA; Azacitidine results in increased expression of HNF1A protein
CTD PMID:25953102 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression ISO Azacitidine results in increased expression of HNF4A mRNA CTD PMID:27590069 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hoxa1 homeobox A1 multiple interactions
increases expression
ISO Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA]
Azacitidine results in increased expression of HOXA1 mRNA
CTD PMID:20823114 NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase decreases methylation
multiple interactions
increases expression
ISO Azacitidine results in decreased methylation of HPGD gene
trichostatin A promotes the reaction [Azacitidine results in increased expression of HPGD mRNA]
CTD PMID:19584167 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 affects expression ISO Azacitidine affects the expression of HSD3B1 mRNA CTD PMID:18033690 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hsf1 heat shock transcription factor 1 decreases activity ISO Azacitidine results in decreased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO Azacitidine results in increased expression of ID1 mRNA CTD PMID:19194470 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO Azacitidine results in increased expression of ID3 mRNA CTD PMID:19194470 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein; [Azacitidine results in decreased methylation of CIITA promoter] promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]; [Azacitidine results in increased expression of KIR2DL4 protein] which results in increased secretion of IFNG protein CTD PMID:18829986 PMID:18945643 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions
increases expression
ISO Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein]
Azacitidine results in increased expression of IGFBP1 mRNA
CTD PMID:20823114 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO Azacitidine results in increased expression of IGFBP4 mRNA CTD PMID:20823114 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Il12b interleukin 12B increases expression ISO Azacitidine results in increased expression of IL12B mRNA CTD PMID:20823114 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP
ISO
Azacitidine results in increased expression of IL1B mRNA
Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 mRNA]]; Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 protein]]
CTD PMID:17156202 PMID:32894642 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions ISO Azacitidine inhibits the reaction [IL2 protein results in increased secretion of GZMB protein]; Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein] CTD PMID:19394699 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 affects methylation ISO Azacitidine affects the methylation of IL4 promoter CTD PMID:18158872 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 affects secretion
affects methylation
ISO Azacitidine affects the secretion of IL6 protein
Azacitidine affects the methylation of IL6 promoter
CTD PMID:18158872 PMID:18443271 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor affects expression
multiple interactions
ISO [Azacitidine affects the expression of IL6R protein] which affects the expression of BCL2L1 protein; Azacitidine affects the expression of IL6R mRNA
[Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein
CTD PMID:18443271 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Isca1 iron-sulfur cluster assembly 1 increases expression ISO Azacitidine results in increased expression of ISCA1 mRNA CTD PMID:19194470 NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Azacitidine results in decreased expression of ITGB1 mRNA CTD PMID:20823114 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression ISO Azacitidine results in decreased expression of ITGB2 mRNA CTD PMID:19194470 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Itprid2 ITPR interacting domain containing 2 increases expression ISO Azacitidine results in increased expression of ITPRID2 mRNA CTD PMID:20823114 NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978
JBrowse link
G Kdr kinase insert domain receptor increases expression EXP Azacitidine results in increased expression of KDR mRNA CTD PMID:18037191 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kif2c kinesin family member 2C multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of KIF2C mRNA CTD PMID:18720364 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Kir3dl1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 increases expression
decreases methylation
ISO Azacitidine results in increased expression of KIR3DL1 mRNA; Azacitidine results in increased expression of KIR3DL1 protein
Azacitidine results in decreased methylation of KIR3DL1 promoter
CTD PMID:18945643 PMID:19394699 NCBI chr 1:69,715,529...69,754,050
Ensembl chr 1:69,715,535...69,754,050
JBrowse link
G Klf6 Kruppel-like factor 6 increases expression
multiple interactions
ISO Azacitidine results in increased expression of KLF6 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of KLF6 mRNA]
CTD PMID:21245298 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Krt19 keratin 19 increases expression ISO Azacitidine results in increased expression of KRT19 mRNA CTD PMID:20823114 NCBI chr10:85,075,835...85,080,552 JBrowse link
G Krt32 keratin 32 increases expression ISO Azacitidine results in increased expression of KRT32 mRNA CTD PMID:20823114 NCBI chr10:85,013,555...85,020,534
Ensembl chr10:85,013,554...85,020,534
JBrowse link
G Krt8 keratin 8 multiple interactions
increases expression
ISO Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA]
Azacitidine results in increased expression of KRT8 mRNA
CTD PMID:20823114 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lama1 laminin subunit alpha 1 affects localization ISO Azacitidine affects the localization of LAMA1 protein CTD PMID:18033690 NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478
JBrowse link
G Lamb2 laminin subunit beta 2 increases expression ISO Azacitidine results in increased expression of LAMB2 mRNA CTD PMID:20823114 NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549
JBrowse link
G Ldhb lactate dehydrogenase B increases expression ISO Azacitidine results in increased expression of LDHB mRNA CTD PMID:23437403 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Lims1 LIM zinc finger domain containing 1 increases expression ISO Azacitidine results in increased expression of LIMS1 mRNA CTD PMID:19194470 NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor decreases expression ISO Azacitidine results in decreased expression of LITAF mRNA CTD PMID:19194470 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G LOC100911664 uncharacterized LOC100911664 increases expression ISO Azacitidine results in increased expression of C6ORF62 mRNA CTD PMID:19194470 NCBI chr17:40,256,211...40,267,851
Ensembl chr17:40,256,211...40,276,020
JBrowse link
G LOC102553180 protocadherin alpha-1-like affects methylation ISO Azacitidine affects the methylation of PCDHA1 promoter CTD PMID:18204046
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO Azacitidine results in increased expression of HSPA6 mRNA CTD PMID:19194470 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Ltb4r leukotriene B4 receptor decreases expression ISO Azacitidine results in decreased expression of LTB4R mRNA CTD PMID:20823114 NCBI chr15:29,263,126...29,265,716 JBrowse link
G Lyz2 lysozyme 2 increases expression ISO Azacitidine results in increased expression of LYZ mRNA CTD PMID:19194470 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 decreases expression ISO Azacitidine results in decreased expression of MAD1L1 mRNA CTD PMID:19194470 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Map1a microtubule-associated protein 1A decreases expression ISO Azacitidine results in decreased expression of MAP1A mRNA CTD PMID:20823114 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression ISO Azacitidine results in decreased expression of MAP2K5 mRNA CTD PMID:20823114 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Azacitidine results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of MCM5 mRNA CTD PMID:18720364 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 increases expression ISO Azacitidine results in increased expression of MDC1 mRNA CTD PMID:20823114 NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Azacitidine results in increased expression of MDM2 mRNA CTD PMID:20823114 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mecp2 methyl CpG binding protein 2 multiple interactions ISO Azacitidine inhibits the reaction [MECP2 protein binds to CCNA1 promoter] CTD PMID:17698632 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Mef2a myocyte enhancer factor 2a increases expression
affects expression
ISO Azacitidine results in increased expression of MEF2A
Azacitidine affects the expression of MEF2A protein
CTD PMID:12094073 PMID:19002953 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Mef2d myocyte enhancer factor 2D affects expression
increases expression
ISO Azacitidine affects the expression of MEF2D protein
Azacitidine results in increased expression of MEF2D
CTD PMID:12094073 PMID:19002953 NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457
JBrowse link
G Megf6 multiple EGF-like-domains 6 decreases expression ISO Azacitidine results in decreased expression of MEGF6 mRNA CTD PMID:19194470 NCBI chr 5:164,738,272...164,839,142
Ensembl chr 5:164,738,352...164,839,139
JBrowse link
G Mesd mesoderm development LRP chaperone decreases expression EXP Azacitidine results in decreased expression of MESD protein CTD PMID:17105402 NCBI chr 1:137,866,707...137,879,999
Ensembl chr 1:137,874,242...137,879,999
JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression ISO Azacitidine results in decreased expression of MFAP2 mRNA CTD PMID:20823114 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing affects expression ISO Azacitidine affects the expression of MFGE8 mRNA CTD PMID:18033690 NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression
decreases methylation
ISO Azacitidine results in increased expression of MGMT mRNA
Azacitidine results in decreased methylation of MGMT protein
CTD PMID:7511991 PMID:12807730 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of MKI67 mRNA CTD PMID:18720364 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Azacitidine results in increased expression of MMP1 mRNA CTD PMID:20823114 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO metacept-1 inhibits the reaction [Azacitidine results in increased expression of MMP9] CTD PMID:19148494 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Morf4l2 mortality factor 4 like 2 decreases expression ISO Azacitidine results in decreased expression of MORF4L2 mRNA CTD PMID:20823114 NCBI chr  X:100,082,562...100,093,658
Ensembl chr  X:100,082,404...100,093,728
JBrowse link
G Mov10l1 Mov10 like RISC complex RNA helicase 1 increases expression ISO Azacitidine results in increased expression of MOV10L1 mRNA CTD PMID:20823114 NCBI chr 7:120,070,171...120,135,406
Ensembl chr 7:120,070,135...120,134,765
JBrowse link
G Msrb2 methionine sulfoxide reductase B2 increases expression ISO Azacitidine results in increased expression of MSRB2 mRNA CTD PMID:19194470 NCBI chr17:81,974,378...82,000,044
Ensembl chr17:81,974,196...82,000,043
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Azacitidine results in decreased expression of MTHFD2 mRNA CTD PMID:20823114 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mtrex Mtr4 exosome RNA helicase increases expression ISO Azacitidine results in increased expression of MTREX mRNA CTD PMID:20823114 NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions
ISO Azacitidine analog results in decreased expression of MYC mRNA
MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]
CTD PMID:18045574 PMID:19451745 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myf5 myogenic factor 5 increases expression ISO Azacitidine results in increased expression of MYF5 mRNA CTD PMID:18938140 NCBI chr 7:42,802,946...42,806,177
Ensembl chr 7:42,802,946...42,806,177
JBrowse link
G Myh7 myosin heavy chain 7 increases expression EXP Azacitidine results in increased expression of MYH7 mRNA; Azacitidine results in increased expression of MYH7 protein CTD PMID:17105402 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Myl2 myosin light chain 2 increases expression EXP Azacitidine results in increased expression of MYL2 mRNA CTD PMID:17105402 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983
JBrowse link
G Myod1 myogenic differentiation 1 increases expression EXP
ISO
Azacitidine results in increased expression of MYOD1 mRNA CTD PMID:18037191 PMID:18938140 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
JBrowse link
G Myog myogenin increases expression ISO Azacitidine results in increased expression of MYOG mRNA CTD PMID:18938140 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
G Ncam1 neural cell adhesion molecule 1 increases expression EXP Azacitidine results in increased expression of NCAM1 mRNA CTD PMID:18037191 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link
G Nefl neurofilament light chain increases expression ISO Azacitidine results in increased expression of NEFL mRNA CTD PMID:20823114 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 increases expression ISO Azacitidine results in increased expression of NFATC1 mRNA CTD PMID:20823114 NCBI chr18:74,046,421...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression
multiple interactions
ISO Azacitidine results in increased expression of NIBAN1 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of NIBAN1 mRNA]
CTD PMID:21245298 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Nkx2-5 NK2 homeobox 5 increases expression ISO Azacitidine results in increased expression of NKX2-5 mRNA CTD PMID:18557828 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Nlgn3 neuroligin 3 increases expression ISO Azacitidine results in increased expression of NLGN3 mRNA CTD PMID:20823114 NCBI chr  X:66,427,926...66,457,378
Ensembl chr  X:66,429,458...66,451,876
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression EXP Azacitidine results in increased expression of NME2 protein CTD PMID:17105402 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nmi N-myc (and STAT) interactor increases expression ISO Azacitidine results in increased expression of NMI mRNA CTD PMID:21245298 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498
JBrowse link
G Nom1 nucleolar protein with MIF4G domain 1 decreases expression ISO Azacitidine results in decreased expression of NOM1 mRNA CTD PMID:20823114 NCBI chr 4:5,891,220...5,910,741
Ensembl chr 4:5,892,909...5,909,709
JBrowse link
G Nphp1 nephrocystin 1 increases expression ISO Azacitidine results in increased expression of NPHP1 mRNA CTD PMID:20823114 NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:114,960,650...115,016,234
JBrowse link
G Nppa natriuretic peptide A increases expression ISO Azacitidine results in increased expression of NPPA CTD PMID:15005238 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B increases expression ISO Azacitidine results in increased expression of NPPB CTD PMID:15005238 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]] CTD PMID:17682057 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [metacept-1 co-treated with Azacitidine] results in increased expression of NR4A1 CTD PMID:19148494 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 decreases expression ISO Azacitidine results in decreased expression of NRIP1 mRNA CTD PMID:20823114 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Nrn1 neuritin 1 decreases expression ISO Azacitidine results in decreased expression of NRN1 mRNA CTD PMID:19194470 NCBI chr17:28,129,969...28,138,898
Ensembl chr17:28,129,977...28,138,896
JBrowse link
G Nt5e 5' nucleotidase, ecto increases expression ISO Azacitidine results in increased expression of NT5E mRNA CTD PMID:20823114 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
JBrowse link
G Nts neurotensin decreases expression ISO Azacitidine results in decreased expression of NTS mRNA CTD PMID:20823114 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of NUSAP1 mRNA CTD PMID:18720364 NCBI chr 3:106,603,273...106,633,624
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 increases expression ISO Azacitidine results in increased expression of NXT2 mRNA CTD PMID:19194470 NCBI chr  X:105,855,616...105,862,902
Ensembl chr  X:105,855,608...105,862,899
JBrowse link
G Ocln occludin increases expression ISO Azacitidine results in increased expression of OCLN mRNA CTD PMID:18661270 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Ogfrl1 opioid growth factor receptor-like 1 increases expression ISO Azacitidine results in increased expression of OGFRL1 mRNA CTD PMID:20823114 NCBI chr 9:25,828,865...25,842,424
Ensembl chr 9:25,828,869...25,842,352
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression
decreases methylation
ISO Azacitidine results in decreased expression of OGG1 protein
Azacitidine results in decreased methylation of OGG1 promoter
CTD PMID:22064374 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Olr1201 olfactory receptor 1201 increases expression ISO Azacitidine results in increased expression of OR8B8 mRNA CTD PMID:20823114 NCBI chr 8:37,693,578...37,694,510
Ensembl chr 8:37,693,499...37,694,547
JBrowse link
G Oxr1 oxidation resistance 1 increases expression ISO Azacitidine results in increased expression of OXR1 mRNA CTD PMID:20823114 NCBI chr 7:72,528,782...72,965,666
Ensembl chr 7:72,528,786...72,965,666
JBrowse link
G Oxtr oxytocin receptor decreases expression ISO Azacitidine results in decreased expression of OXTR mRNA CTD PMID:21245298 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta increases expression EXP
ISO
Azacitidine results in increased expression of P4HB protein
Azacitidine results in increased expression of P4HB mRNA
CTD PMID:17105402 PMID:20823114 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Paep progestagen associated endometrial protein decreases expression ISO Azacitidine results in decreased expression of PAEP mRNA CTD PMID:20823114 NCBI chr 3:8,531,136...8,534,430
Ensembl chr 3:8,531,138...8,534,430
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 increases expression ISO Azacitidine results in increased expression of PAK1 mRNA CTD PMID:20823114 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
G Pank3 pantothenate kinase 3 decreases expression ISO Azacitidine results in decreased expression of PANK3 mRNA CTD PMID:19194470 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Azacitidine results in increased cleavage of PARP1 protein
Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein]
CTD PMID:32278510 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax4 paired box 4 increases expression ISO Azacitidine results in increased expression of PAX4 mRNA CTD PMID:18949370 NCBI chr 4:57,058,453...57,065,995
Ensembl chr 4:57,058,462...57,063,408
JBrowse link
G Pcdh18 protocadherin 18 decreases expression ISO Azacitidine results in decreased expression of PCDH18 mRNA CTD PMID:20823114 NCBI chr 2:133,831,996...133,845,992
Ensembl chr 2:133,832,001...133,845,883
JBrowse link
G Pcdha1 protocadherin alpha 1 affects methylation ISO Azacitidine affects the methylation of PCDHA1 promoter CTD PMID:18204046
G Pcdha10 protocadherin alpha 10 affects methylation ISO Azacitidine affects the methylation of PCDHA10 promoter CTD PMID:18204046
G Pcdha11 protocadherin alpha 11 affects methylation ISO Azacitidine affects the methylation of PCDHA11 promoter CTD PMID:18204046
G Pcdha12 protocadherin alpha 12 affects methylation ISO Azacitidine affects the methylation of PCDHA12 promoter CTD PMID:18204046
G Pcdha2 protocadherin alpha 2 affects methylation ISO Azacitidine affects the methylation of PCDHA2 promoter CTD PMID:18204046
G Pcdha3 protocadherin alpha 3 affects methylation ISO Azacitidine affects the methylation of PCDHA3 promoter CTD PMID:18204046
G Pcdha4 protocadherin alpha 4 affects methylation ISO Azacitidine affects the methylation of PCDHA4 promoter CTD PMID:18204046 NCBI chr18:28,581,040...28,846,214 JBrowse link
G Pcdha5 protocadherin alpha 5 affects methylation ISO Azacitidine affects the methylation of PCDHA5 promoter CTD PMID:18204046
G Pcdha6 protocadherin alpha 6 affects methylation ISO Azacitidine affects the methylation of PCDHA6 promoter CTD PMID:18204046
G Pcdha7 protocadherin alpha 7 affects methylation ISO Azacitidine affects the methylation of PCDHA7 promoter CTD PMID:18204046
G Pcdha9 protocadherin alpha 9 affects methylation ISO Azacitidine affects the methylation of PCDHA8 promoter; Azacitidine affects the methylation of PCDHA9 promoter CTD PMID:18204046
G Pcdhb20 protocadherin beta 20 decreases expression ISO Azacitidine results in decreased expression of PCDHB14 mRNA CTD PMID:20823114 NCBI chr18:29,211,883...29,215,258
Ensembl chr18:29,211,883...29,215,258
JBrowse link
G Pcdhb5 protocadherin beta 5 decreases expression ISO Azacitidine results in decreased expression of PCDHB4 mRNA CTD PMID:20823114 NCBI chr18:29,024,315...29,032,183
Ensembl chr18:29,028,382...29,053,259
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression
multiple interactions
EXP Azacitidine results in decreased expression of PCNA protein
[Cisplatin co-treated with Azacitidine] results in decreased expression of PCNA protein
CTD PMID:19723570 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression ISO Azacitidine results in increased expression of PDK1 mRNA CTD PMID:20823114 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression
decreases methylation
ISO Azacitidine results in increased expression of PDK4 protein
Azacitidine results in decreased methylation of PDK4 promoter
CTD PMID:28003426 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression EXP Azacitidine results in increased expression of PECAM1 mRNA CTD PMID:18037191 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pfn1 profilin 1 increases expression ISO Azacitidine results in increased expression of PFN1 mRNA CTD PMID:20823114 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Phactr2 phosphatase and actin regulator 2 increases expression ISO Azacitidine results in increased expression of PHACTR2 mRNA CTD PMID:20823114 NCBI chr 1:7,591,254...7,860,431
Ensembl chr 1:7,597,927...7,860,289
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha decreases expression ISO Azacitidine results in decreased expression of PIP5K1A mRNA CTD PMID:19194470 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 decreases expression ISO Azacitidine results in decreased expression of PITPNC1 mRNA CTD PMID:20823114 NCBI chr10:92,163,558...92,428,971 JBrowse link
G Pitx3 paired-like homeodomain 3 increases expression EXP Azacitidine results in increased expression of PITX3 mRNA CTD PMID:27415467 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892
JBrowse link
G Pja1 praja ring finger ubiquitin ligase 1 increases expression ISO Azacitidine results in increased expression of PJA1 mRNA CTD PMID:19194470 NCBI chr  X:64,580,938...64,585,864
Ensembl chr  X:64,580,849...64,585,833
JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel increases expression ISO Azacitidine results in increased expression of PKD2L1 mRNA CTD PMID:20823114 NCBI chr 1:243,032,853...243,070,031
Ensembl chr 1:243,032,913...243,070,031
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO Azacitidine results in increased expression of PKM mRNA CTD PMID:20823114 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Plcb1 phospholipase C beta 1 decreases methylation
decreases response to substance
increases response to substance
increases expression
ISO Azacitidine results in decreased methylation of PLCB1 promoter
PLCB1 promoter modified form results in decreased susceptibility to Azacitidine
PLCB1 mRNA results in increased susceptibility to Azacitidine; PLCB1 protein results in increased susceptibility to Azacitidine
Azacitidine results in increased expression of PLCB1 mRNA; Azacitidine results in increased expression of PLCB1 protein
CTD PMID:19805378 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Plpp1 phospholipid phosphatase 1 increases expression ISO Azacitidine results in increased expression of PLPP1 mRNA CTD PMID:19194470 NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268
JBrowse link
G Pls3 plastin 3 decreases expression ISO Azacitidine results in decreased expression of PLS3 mRNA CTD PMID:20823114 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Pml PML nuclear body scaffold increases expression ISO Azacitidine results in increased expression of PML mRNA CTD PMID:19194470 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases methylation
increases expression
ISO Azacitidine results in decreased methylation of PPARG promoter
Azacitidine results in increased expression of PPARG mRNA
CTD PMID:19589179 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions
increases expression
decreases methylation
ISO Azacitidine promotes the reaction [CREB1 protein modified form binds to PPP2CA promoter]
Azacitidine results in increased expression of PPP2CA mRNA
Azacitidine results in decreased methylation of PPP2CA promoter
CTD PMID:19155497 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Prdx4 peroxiredoxin 4 decreases expression EXP Azacitidine results in decreased expression of PRDX4 protein CTD PMID:17105402 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066
JBrowse link
G Prf1 perforin 1 multiple interactions ISO Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein] CTD PMID:19394699 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Prl prolactin multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL protein CTD PMID:20823114 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prom1 prominin 1 increases expression EXP Azacitidine results in increased expression of PROM1 mRNA CTD PMID:18037191 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
JBrowse link
G Prss12 serine protease 12 decreases expression ISO Azacitidine results in decreased expression of PRSS12 mRNA CTD PMID:20823114 NCBI chr 2:211,624,134...211,684,126
Ensembl chr 2:211,624,134...211,684,126
JBrowse link
G Psen1 presenilin 1 decreases methylation
multiple interactions
ISO Azacitidine results in decreased methylation of PSEN1 promoter
Betaine inhibits the reaction [Azacitidine results in decreased methylation of PSEN1 promoter]
CTD PMID:19635394 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter] CTD PMID:22841775 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression ISO Azacitidine results in decreased expression of PTHLH mRNA CTD PMID:20823114 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator increases expression ISO Azacitidine results in increased expression of PTPA mRNA CTD PMID:20823114 NCBI chr 3:13,689,742...13,720,287
Ensembl chr 3:13,689,741...13,722,549
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression ISO Azacitidine results in increased expression of PTPRC mRNA CTD PMID:19194470 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O increases expression EXP Azacitidine results in increased expression of PTPRO mRNA CTD PMID:14508512 NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771
JBrowse link
G Rab13 RAB13, member RAS oncogene family decreases methylation ISO Azacitidine results in decreased methylation of RAB13 promoter CTD PMID:19194470 NCBI chr 2:175,674,894...175,680,043
Ensembl chr 2:175,675,005...175,680,036
JBrowse link
G Rab1b RAB1B, member RAS oncogene family increases expression ISO Azacitidine results in increased expression of RAB1B mRNA CTD PMID:20823114 NCBI chr 1:202,405,759...202,413,850
Ensembl chr 1:202,405,759...202,413,868
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 increases expression ISO Azacitidine results in increased expression of RACGAP1 mRNA CTD PMID:20823114 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Ranbp2 RAN binding protein 2 increases expression ISO Azacitidine results in increased expression of RANBP2 mRNA CTD PMID:19194470 NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481
JBrowse link
G Rasa3 RAS p21 protein activator 3 increases expression ISO Azacitidine results in increased expression of RASA3 mRNA CTD PMID:20823114 NCBI chr16:75,855,360...75,969,349
Ensembl chr16:75,855,265...75,970,804
JBrowse link
G Rcn1 reticulocalbin 1 decreases expression ISO Azacitidine results in decreased expression of RCN1 mRNA CTD PMID:20823114 NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:91,841,052...91,855,295
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects localization ISO Azacitidine affects the localization of RELA protein CTD PMID:18443271 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ret ret proto-oncogene decreases expression ISO Azacitidine results in decreased expression of RET mRNA CTD PMID:20823114 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Rfc3 replication factor C subunit 3 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of RFC3 mRNA CTD PMID:18720364 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778
JBrowse link
G Rhob ras homolog family member B multiple interactions ISO [trichostatin A co-treated with Azacitidine] results in increased expression of RHOB protein; Azacitidine promotes the reaction [trichostatin A results in increased expression of RHOB mRNA] CTD PMID:18047684 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rin1 Ras and Rab interactor 1 increases expression ISO Azacitidine results in increased expression of RIN1 mRNA CTD PMID:20823114 NCBI chr 1:202,355,729...202,362,731
Ensembl chr 1:202,355,890...202,362,729
JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 increases expression ISO Azacitidine results in increased expression of RPP21 mRNA CTD PMID:20823114 NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Azacitidine results in decreased phosphorylation of RPS6 protein CTD PMID:21245298 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rpsa ribosomal protein SA decreases expression ISO Azacitidine results in decreased expression of RPSA mRNA CTD PMID:20823114 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of RRM2 mRNA CTD PMID:18720364 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO Azacitidine results in increased expression of RRM2B mRNA CTD PMID:19010910 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
JBrowse link
G RT1-Da RT1 class II, locus Da multiple interactions ISO [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein CTD PMID:18829986 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions ISO Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL4 promoter] CTD PMID:18945643 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Runx3 RUNX family transcription factor 3 affects methylation ISO Azacitidine affects the methylation of RUNX3 gene CTD PMID:18058463 NCBI chr 5:147,393,926...147,419,161
Ensembl chr 5:147,360,994...147,419,156
JBrowse link
G S100a14 S100 calcium binding protein A14 decreases expression ISO Azacitidine results in decreased expression of S100A14 mRNA CTD PMID:20823114 NCBI chr 2:176,008,395...176,010,423
Ensembl chr 2:176,008,395...176,010,423
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Azacitidine results in increased expression of S100A9 mRNA CTD PMID:19194470 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Sall4 spalt-like transcription factor 4 affects methylation ISO Azacitidine affects the methylation of SALL4 promoter CTD PMID:17546590 NCBI chr 3:157,474,067...157,491,055
Ensembl chr 3:157,474,642...157,490,822
JBrowse link
G Scamp4 secretory carrier membrane protein 4 increases expression ISO Azacitidine results in increased expression of SCAMP4 mRNA CTD PMID:20823114 NCBI chr 7:9,101,504...9,113,929
Ensembl chr 7:9,101,489...9,113,967
JBrowse link
G Sdcbp syndecan binding protein decreases expression ISO Azacitidine results in decreased expression of SDCBP mRNA CTD PMID:20823114 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
JBrowse link
G Sema3a semaphorin 3A increases expression ISO Azacitidine results in increased expression of SEMA3A mRNA CTD PMID:20823114 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
JBrowse link
G Sema6c semaphorin 6C increases expression ISO Azacitidine results in increased expression of SEMA6C mRNA CTD PMID:20823114 NCBI chr 2:182,733,635...182,750,066
Ensembl chr 2:182,737,474...182,746,856
JBrowse link
G Senp3 SUMO specific peptidase 3 increases expression ISO Azacitidine results in increased expression of SENP3 mRNA CTD PMID:20823114 NCBI chr10:54,390,698...54,399,590
Ensembl chr10:54,390,694...54,399,593
JBrowse link
G Slbp stem-loop binding protein multiple interactions ISO Azacitidine inhibits the reaction [sodium arsenite results in decreased expression of SLBP mRNA] CTD PMID:25266719 NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906
JBrowse link
G Slc28a1 solute carrier family 28 member 1 increases response to substance
multiple interactions
increases uptake
ISO SLC28A1 protein results in increased susceptibility to Azacitidine
[SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein; Sodium affects the reaction [SLC28A1 protein results in increased uptake of Azacitidine]
CTD PMID:19139132 NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464
JBrowse link
G Slc29a2 solute carrier family 29 member 2 decreases expression ISO Azacitidine results in decreased expression of SLC29A2 mRNA CTD PMID:19194470 NCBI chr 1:202,327,641...202,335,185
Ensembl chr 1:202,327,354...202,335,171
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
increases expression
ISO [Azacitidine co-treated with Butyrates] affects the expression of SLC5A5 mRNA
Azacitidine results in increased expression of SLC5A5 mRNA
CTD PMID:16954431 PMID:17164311 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
JBrowse link
G Snu13 small nuclear ribonucleoprotein 13 increases expression ISO Azacitidine results in increased expression of SNU13 mRNA CTD PMID:20823114 NCBI chr 7:113,565,903...113,570,871
Ensembl chr 7:113,565,295...113,570,872
JBrowse link
G Socs3 suppressor of cytokine signaling 3 affects expression ISO Azacitidine affects the expression of SOCS3 protein CTD PMID:18443271 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sox13 SRY-box transcription factor 13 decreases expression ISO Azacitidine results in decreased expression of SOX13 mRNA CTD PMID:20823114 NCBI chr13:44,831,097...44,875,522
Ensembl chr13:44,831,085...44,875,762
JBrowse link
G Sox2 SRY-box transcription factor 2 increases expression EXP Azacitidine results in increased expression of SOX2 mRNA CTD PMID:27415467 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338
JBrowse link
G Sox8 SRY-box transcription factor 8 decreases expression ISO Azacitidine results in decreased expression of SOX8 mRNA CTD PMID:18033690 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818
JBrowse link
G Sox9 SRY-box transcription factor 9 affects expression ISO Azacitidine affects the expression of SOX9 mRNA CTD PMID:18033690 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions
decreases expression
ISO Azacitidine promotes the reaction [SP1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [SP1 protein binds to KIR2DL4 promoter]
Azacitidine results in decreased expression of SP1 mRNA
Azacitidine promotes the reaction [SP1 protein binds to AQP5 promoter]
CTD PMID:17198683 PMID:18945643 PMID:20823114 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Sp7 Sp7 transcription factor increases expression ISO Azacitidine results in increased expression of SP7 mRNA CTD PMID:17085970 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Spag5 sperm associated antigen 5 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of SPAG5 mRNA CTD PMID:18720364 NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked decreases expression ISO Azacitidine results in decreased expression of SRPX mRNA CTD PMID:19194470 NCBI chr  X:12,676,984...12,751,296 JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 decreases expression ISO Azacitidine results in decreased expression of SRSF7 mRNA CTD PMID:20823114 NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
JBrowse link
G Ssx2ip SSX family member 2 interacting protein increases expression ISO Azacitidine results in increased expression of SSX2IP mRNA CTD PMID:20823114 NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745
JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 increases expression ISO Azacitidine results in increased expression of ST3GAL6 mRNA CTD PMID:19194470 NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 decreases expression ISO Azacitidine results in decreased expression of ST8SIA2 mRNA CTD PMID:20823114 NCBI chr 1:127,766,669...127,838,017
Ensembl chr 1:127,762,573...127,838,091
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein CTD PMID:18443271 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stc2 stanniocalcin 2 decreases expression ISO Azacitidine results in decreased expression of STC2 mRNA CTD PMID:19194470 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
JBrowse link
G Stk38 serine/threonine kinase 38 decreases expression ISO Azacitidine results in decreased expression of STK38 mRNA CTD PMID:20823114 NCBI chr20:7,034,245...7,067,803
Ensembl chr20:7,034,242...7,068,198
JBrowse link
G Sulf1 sulfatase 1 decreases expression ISO Azacitidine results in decreased expression of SULF1 mRNA CTD PMID:20823114 NCBI chr 5:6,362,896...6,526,174
Ensembl chr 5:6,362,911...6,525,584
JBrowse link
G Sult1c2a sulfotransferase family, cytosolic, 1C, member 2a increases expression ISO Azacitidine results in increased expression of SULT1C2 mRNA CTD PMID:19194470 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734
JBrowse link
G Tat tyrosine aminotransferase increases expression ISO Azacitidine results in increased expression of TAT mRNA CTD PMID:27590069 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Tbc1d4 TBC1 domain family, member 4 decreases expression ISO Azacitidine results in decreased expression of TBC1D4 mRNA CTD PMID:19194470 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
JBrowse link
G Tcea1 transcription elongation factor A1 decreases expression ISO Azacitidine results in decreased expression of TCEA1 mRNA CTD PMID:20823114 NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745
JBrowse link
G Tecpr2 tectonin beta-propeller repeat containing 2 increases expression ISO Azacitidine results in increased expression of TECPR2 mRNA CTD PMID:19194470 NCBI chr 6:129,899,541...130,001,975
Ensembl chr 6:129,899,636...130,001,974
JBrowse link
G Tek TEK receptor tyrosine kinase increases expression EXP Azacitidine results in increased expression of TEK mRNA CTD PMID:18037191 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tert telomerase reverse transcriptase decreases expression
multiple interactions
decreases methylation
decreases activity
ISO Azacitidine analog results in decreased expression of TERT mRNA; Azacitidine results in decreased expression of TERT mRNA
E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]; MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]
Azacitidine results in decreased methylation of TERT promoter
CTD PMID:18045574 PMID:19451745 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 increases expression ISO Azacitidine results in increased expression of TFE3 mRNA CTD PMID:19194470 NCBI chr  X:14,729,547...14,742,830
Ensembl chr  X:14,729,550...14,742,571
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Azacitidine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein
Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter]; Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein]
CTD PMID:18493985 PMID:22841775 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thumpd1 THUMP domain containing 1 increases expression ISO Azacitidine results in increased expression of THUMPD1 mRNA CTD PMID:19194470 NCBI chr 1:174,078,875...174,084,915 JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Azacitidine results in increased expression of TIMP1 mRNA CTD PMID:20823114 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tjp1 tight junction protein 1 increases expression ISO Azacitidine results in increased expression of TJP1 mRNA CTD PMID:18661270 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tmed3 transmembrane p24 trafficking protein 3 increases expression ISO Azacitidine results in increased expression of TMED3 mRNA CTD PMID:20823114 NCBI chr 8:90,241,516...90,249,429
Ensembl chr 8:90,241,516...90,249,346
JBrowse link
G Tmpo thymopoietin multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TMPO mRNA CTD PMID:18720364 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Tnc tenascin C decreases expression ISO Azacitidine results in decreased expression of TNC mRNA CTD PMID:20823114 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnf tumor necrosis factor increases expression
increases response to substance
EXP
ISO
Azacitidine results in increased expression of TNF mRNA
Azacitidine results in increased susceptibility to TNF protein
CTD PMID:17156202 PMID:18829727 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases response to substance ISO Azacitidine results in increased susceptibility to TNFSF10 protein CTD PMID:18829727 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnni3 troponin I3, cardiac type increases expression EXP Azacitidine results in increased expression of TNNI3 protein CTD PMID:17105402 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Tnnt2 troponin T2, cardiac type increases expression EXP Azacitidine results in increased expression of TNNT2 protein CTD PMID:22496879 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TOP2A mRNA; [Curcumin co-treated with Azacitidine] results in decreased expression of TOP2A mRNA CTD PMID:18348204 PMID:18720364 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tp73 tumor protein p73 multiple interactions ISO TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]; TP73 protein promotes the reaction [Azacitidine results in increased expression of KLF6 mRNA]; TP73 protein promotes the reaction [Azacitidine results in increased expression of NIBAN1 mRNA] CTD PMID:21245298 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Tpd52 tumor protein D52 increases expression EXP Azacitidine results in increased expression of TPD52 mRNA CTD PMID:27415467 NCBI chr 2:92,735,246...92,816,079
Ensembl chr 2:92,735,620...92,816,622
JBrowse link
G Tpm2 tropomyosin 2 increases expression ISO Azacitidine results in increased expression of TPM2 mRNA CTD PMID:20823114 NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992
JBrowse link
G Tpo thyroid peroxidase increases expression ISO Azacitidine results in increased expression of TPO mRNA CTD PMID:17679169 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
JBrowse link
G Tpsg1 tryptase gamma 1 decreases expression ISO Azacitidine results in decreased expression of TPSG1 mRNA CTD PMID:20823114 NCBI chr10:14,386,352...14,390,258
Ensembl chr10:14,386,352...14,390,258
JBrowse link
G Trh thyrotropin releasing hormone decreases expression ISO Azacitidine results in decreased expression of TRH mRNA CTD PMID:19194470 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
G Trib1 tribbles pseudokinase 1 decreases expression ISO Azacitidine results in decreased expression of TRIB1 mRNA CTD PMID:19194470 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
JBrowse link
G Trim8 tripartite motif-containing 8 increases expression ISO Azacitidine results in increased expression of TRIM8 mRNA CTD PMID:19194470 NCBI chr 1:245,369,632...245,384,513
Ensembl chr 1:245,369,632...245,384,513
JBrowse link
G Tsc1 TSC complex subunit 1 multiple interactions ISO [Azacitidine affects the methylation of TSC1 promoter] which affects the expression of TSC1 mRNA CTD PMID:18538015 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674
JBrowse link
G Tsc2 TSC complex subunit 2 decreases methylation
multiple interactions
increases expression
ISO Azacitidine results in decreased methylation of TSC2 promoter
[Azacitidine affects the methylation of TSC2 promoter] which affects the expression of TSC2 mRNA
Azacitidine results in increased expression of TSC2 mRNA
CTD PMID:18538015 PMID:19250671 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO Azacitidine results in increased expression of TSHR mRNA CTD PMID:17679169 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
JBrowse link
G Tspan32 tetraspanin 32 decreases expression ISO Azacitidine results in decreased expression of TSPAN32 mRNA CTD PMID:19194470 NCBI chr 1:198,190,128...198,204,447
Ensembl chr 1:198,190,164...198,204,445
JBrowse link
G Ttk Ttk protein kinase multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TTK mRNA CTD PMID:18720364 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of UBE2C mRNA CTD PMID:18720364 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Uhmk1 U2AF homology motif kinase 1 increases expression ISO Azacitidine results in increased expression of UHMK1 mRNA CTD PMID:20823114 NCBI chr13:82,396,646...82,416,292
Ensembl chr13:82,401,187...82,416,292
JBrowse link
G Ush2a usherin increases expression ISO Azacitidine results in increased expression of USH2A mRNA CTD PMID:20823114 NCBI chr13:99,837,445...100,503,935
Ensembl chr13:99,837,445...100,503,922
JBrowse link
G Ushbp1 USH1 protein network component harmonin binding protein 1 decreases expression ISO Azacitidine results in decreased expression of USHBP1 mRNA CTD PMID:20823114 NCBI chr16:18,057,321...18,067,933
Ensembl chr16:18,057,326...18,067,877
JBrowse link
G Vim vimentin decreases expression
increases expression
multiple interactions
EXP
ISO
Azacitidine results in decreased expression of VIM protein
Azacitidine results in increased expression of VIM mRNA; Azacitidine results in increased expression of VIM protein
[Azacitidine co-treated with Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VIM protein
CTD PMID:17105402 PMID:20823114 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Wdr47 WD repeat domain 47 decreases expression ISO Azacitidine results in decreased expression of WDR47 mRNA CTD PMID:19194470 NCBI chr 2:196,226,757...196,287,739
Ensembl chr 2:196,205,238...196,287,739
JBrowse link
G Wnt10b Wnt family member 10B increases expression EXP Azacitidine results in increased expression of WNT10B mRNA CTD PMID:27415467 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892
JBrowse link
G Wnt5a Wnt family member 5A increases expression ISO Azacitidine results in increased expression of WNT5A mRNA CTD PMID:20823114 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 increases expression ISO Azacitidine results in increased expression of WWTR1 mRNA CTD PMID:20823114 NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968
JBrowse link
G Xaf1 XIAP associated factor 1 decreases expression
decreases methylation
increases expression
ISO Azacitidine results in decreased expression of XAF1 mRNA alternative form
Azacitidine results in decreased methylation of XAF1 promoter
Azacitidine results in increased expression of XAF1 mRNA; Azacitidine results in increased expression of XAF1 protein
CTD PMID:19077051 PMID:19549372 NCBI chr10:56,917,284...56,929,791
Ensembl chr10:56,917,121...56,929,770
JBrowse link
G Zfp189 zinc finger protein 189 decreases expression ISO Azacitidine results in decreased expression of ZNF189 mRNA CTD PMID:20823114 NCBI chr 5:63,872,596...63,884,348
Ensembl chr 5:63,872,738...63,884,121
JBrowse link
G Zfp64 zinc finger protein 64 affects methylation ISO Azacitidine affects the methylation of ZFP64 promoter CTD PMID:17546590 NCBI chr 3:157,666,819...157,695,774
Ensembl chr 3:157,633,211...157,695,809
JBrowse link
G Zp3 zona pellucida glycoprotein 3 increases expression ISO Azacitidine results in increased expression of ZP3 mRNA CTD PMID:20823114 NCBI chr12:20,690,547...20,697,513
Ensembl chr12:20,690,547...20,697,513
JBrowse link
acetoacetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 affects binding ISO acetoacetyl CoA binds to HSD17B2 protein CTD PMID:25526675 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acly ATP citrate lyase increases abundance ISO ACLY protein results in increased abundance of Acetyl Coenzyme A CTD PMID:28077572 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G App amyloid beta precursor protein affects localization
increases secretion
multiple interactions
ISO APP protein affects the localization of Acetyl Coenzyme A
Acetyl Coenzyme A results in increased secretion of APP protein modified form
Acetyl Coenzyme A inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form]
IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]
CTD PMID:16122837 PMID:22906069 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Crat carnitine O-acetyltransferase decreases activity EXP Acetyl Coenzyme A deficiency results in decreased activity of CRAT protein CTD PMID:8075222 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor decreases abundance
multiple interactions
ISO ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A
3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]
CTD PMID:25440059 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A] CTD PMID:16122837 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Kat2b lysine acetyltransferase 2B affects binding ISO Acetyl Coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:6,562,525...6,667,064 JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator multiple interactions ISO METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Acetyl Coenzyme A] CTD PMID:30213948 NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
JBrowse link
G Nat1 N-acetyltransferase 1 multiple interactions
affects binding
ISO [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein]; Acetyl Coenzyme A inhibits the reaction [Iodoacetamide results in decreased activity of NAT1 protein]
Acetyl Coenzyme A binds to NAT1 protein
CTD PMID:20545351 PMID:22835378 NCBI chr16:22,218,217...22,238,516 JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
acryloyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Echs1 enoyl-CoA hydratase, short chain 1 increases abundance ISO ECHS1 gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase increases abundance ISO HIBCH gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824
JBrowse link
adenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase decreases metabolic processing
increases metabolic processing
ISO ADA alternative form results in decreased metabolism of Adenosine
ADA protein results in increased metabolism of Adenosine
CTD PMID:16221767 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adora1 adenosine A1 receptor multiple interactions
affects binding
ISO
EXP
Adenosine analog binds to and affects the activity of ADORA1 protein; Adenosine analog binds to and results in decreased activity of ADORA1 protein; PD 81723 affects the reaction [Adenosine analog binds to and affects the activity of ADORA1 protein]; VUF 5455 affects the reaction [Adenosine analog binds to and affects the activity of ADORA1 protein]
[lead acetate results in increased expression of ADORA1 protein] which results in increased abundance of Adenosine; Adenosine analog binds to and results in increased activity of ADORA1 protein
Adenosine binds to ADORA1 protein
CTD PMID:10649980 PMID:11520205 PMID:18404447 PMID:20571079 PMID:20932874 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora2a adenosine A2a receptor multiple interactions
affects binding
ISO Adenosine analog binds to and results in decreased activity of ADORA2A protein; Adenosine promotes the reaction [Lipopolysaccharides results in increased expression of ADORA2A mRNA]
Adenosine binds to ADORA2A protein
CTD PMID:18404447 PMID:20067761 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Adora2b adenosine A2B receptor affects response to substance ISO ADORA2B protein affects the susceptibility to Adenosine CTD PMID:16920807 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Adora3 adenosine A3 receptor multiple interactions
increases expression
affects binding
ISO Adenosine analog binds to and affects the activity of ADORA3 protein; Adenosine analog binds to and results in decreased activity of ADORA3 protein; Adenosine analog binds to and results in increased activity of ADORA3 protein; PD 81723 affects the reaction [Adenosine analog binds to and affects the activity of ADORA3 protein]; VUF 5455 affects the reaction [Adenosine analog binds to and affects the activity of ADORA3 protein]
Adenosine results in increased expression of ADORA3 mRNA
Adenosine binds to ADORA3 protein
CTD PMID:11520205 PMID:18404447 PMID:20067761 PMID:20571079
G Alpi alkaline phosphatase, intestinal multiple interactions ISO Adenosine inhibits the reaction [Methotrexate results in increased activity of ALPI protein] CTD PMID:16598758 NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877
JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 multiple interactions ISO [tofacitinib results in decreased expression of AMPD2 protein] which affects the abundance of Adenosine CTD PMID:25496463 NCBI chr 2:195,707,609...195,720,454
Ensembl chr 2:195,707,610...195,720,271
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases localization
multiple interactions
ISO Adenosine results in increased localization of BAX protein
Thymidine inhibits the reaction [Adenosine results in increased localization of BAX protein]
CTD PMID:11570579 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions
ISO Adenosine results in decreased expression of BCL2L1 mRNA; Adenosine results in decreased expression of BCL2L1 protein
Dipyridamole inhibits the reaction [Adenosine results in decreased expression of BCL2L1 mRNA]; Dipyridamole inhibits the reaction [Adenosine results in decreased expression of BCL2L1 protein]
CTD PMID:20063052 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Adenosine results in decreased expression of BIRC2 mRNA; Adenosine results in decreased expression of BIRC2 protein CTD PMID:20063052 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Adenosine results in decreased expression of BIRC3 mRNA CTD PMID:20063052 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
Dipyridamole inhibits the reaction [Adenosine results in increased activity of CASP3 protein]; Thymidine inhibits the reaction [Adenosine results in increased activity of CASP3 protein] CTD PMID:11570579 PMID:16469385 PMID:17303086 PMID:20063052 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
ISO
EXP
Adenosine results in increased activity of CASP8 protein
Dipyridamole inhibits the reaction [Adenosine results in increased activity of CASP8 protein]
CTD PMID:16469385 PMID:17303086 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
ISO
EXP
Adenosine results in increased activity of CASP9 protein
Thymidine inhibits the reaction [Adenosine results in increased activity of CASP9 protein]
CTD PMID:11570579 PMID:16469385 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cd14 CD14 molecule increases expression ISO Adenosine results in increased expression of CD14 mRNA CTD PMID:21538184 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression
multiple interactions
ISO Adenosine results in decreased expression of CFLAR mRNA; Adenosine results in decreased expression of CFLAR mRNA alternative form; Adenosine results in decreased expression of CFLAR protein
Dipyridamole inhibits the reaction [Adenosine results in decreased expression of CFLAR mRNA alternative form]; Dipyridamole inhibits the reaction [Adenosine results in decreased expression of CFLAR mRNA]; Dipyridamole inhibits the reaction [Adenosine results in decreased expression of CFLAR protein]
CTD PMID:17303086 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cftr CF transmembrane conductance regulator increases activity
multiple interactions
ISO Adenosine results in increased activity of CFTR protein
[Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein
CTD PMID:15039139 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression
multiple interactions
ISO Adenosine results in increased expression of DIABLO mRNA; Adenosine results in increased expression of DIABLO protein
Dipyridamole inhibits the reaction [Adenosine results in increased expression of DIABLO mRNA]; Dipyridamole inhibits the reaction [Adenosine results in increased expression of DIABLO protein]
CTD PMID:20063052 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dpp4 dipeptidylpeptidase 4 decreases expression
multiple interactions
ISO Adenosine results in decreased expression of DPP4 mRNA; Adenosine results in decreased expression of DPP4 protein
[Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 protein; [Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 protein
CTD PMID:16611738 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO Adenosine results in increased expression of ESR1 protein CTD PMID:29360751 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases expression ISO Adenosine results in increased expression of ESR2 protein CTD PMID:29360751 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fadd Fas associated via death domain decreases expression
multiple interactions
ISO Adenosine results in decreased expression of FADD mRNA
Dipyridamole inhibits the reaction [Adenosine results in decreased expression of FADD mRNA]
CTD PMID:17303086 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Faslg Fas ligand increases expression
multiple interactions
ISO Adenosine results in increased expression of FASLG protein
[Adenosine co-treated with Coformycin] results in decreased expression of FASL mRNA
CTD PMID:11992407 PMID:16419169 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression ISO Adenosine results in increased expression of FSHB protein CTD PMID:29360751 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Gzmb granzyme B multiple interactions ISO [Adenosine co-treated with Coformycin] results in decreased expression of GZMB mRNA CTD PMID:11992407 NCBI chr15:30,343,361...30,346,792 JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Adenosine promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Adenosine results in increased expression of HIF1A mRNA CTD PMID:20067761 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of Adenosine
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Adenosine]
CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Adenosine co-treated with Coformycin] results in decreased expression of IFNG protein CTD PMID:11992407 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
ISO Adenosine promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]
Adenosine results in increased expression of IL10 mRNA; Adenosine results in increased expression of IL10 protein
CTD PMID:11023991 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12b interleukin 12B decreases expression
multiple interactions
ISO Adenosine results in decreased expression of IL12B protein
Adenosine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]
CTD PMID:11023991 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Adenosine inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Adenosine inhibits the reaction [IL1B protein results in increased expression of IL1R1]; Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein] CTD PMID:24878381 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions EXP Adenosine inhibits the reaction [IL1B protein results in increased expression of IL1R1] CTD PMID:24878381 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Adenosine co-treated with Coformycin] results in decreased expression of IL2 protein CTD PMID:11992407 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO Adenosine results in increased expression of LY96 mRNA CTD PMID:21538184 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO [Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 protein CTD PMID:16611738 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
ISO Adenosine results in decreased phosphorylation of MAPK3 protein
[Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 protein
CTD PMID:16611738 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions
ISO Adenosine results in decreased expression of MYC protein
Thymidine inhibits the reaction [Adenosine results in decreased expression of MYC protein]; Uridine inhibits the reaction [Adenosine results in decreased expression of MYC protein]
CTD PMID:9808420 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Adenosine co-treated with Homocysteine] results in decreased expression of NFKBIA mRNA CTD PMID:24224954 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 decreases stability
multiple interactions
EXP Adenosine results in decreased stability of NOS2 mRNA
Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]
CTD PMID:24878381 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [alpha,beta-methyleneadenosine 5'-diphosphate results in decreased activity of NT5E protein] inhibits the reaction [Oxygen deficiency results in increased abundance of Adenosine] CTD PMID:23437309 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Adenosine results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prf1 perforin 1 multiple interactions ISO [Adenosine co-treated with Coformycin] results in decreased expression of PRF1 mRNA CTD PMID:11992407 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO [Prostaglandin D2 results in increased activity of PTGDR protein] which results in increased metabolism of Adenosine; [Prostaglandin D2 results in increased activity of PTGDR protein] which results in increased secretion of Adenosine CTD PMID:11562489 NCBI chr15:17,360,304...17,367,679 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein affects the localization of RELA protein modified form]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of RELA protein] CTD PMID:24224954 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ren renin decreases secretion EXP Adenosine results in decreased secretion of REN protein CTD PMID:3044993 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions ISO [Adenosine co-treated with Homocysteine co-treated with TNF protein] results in increased cleavage of RIPK1 protein CTD PMID:24224954 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Slc28a1 solute carrier family 28 member 1 affects transport
multiple interactions
ISO SLC28A1 protein affects the transport of Adenosine
Adenosine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]
CTD PMID:9124315 NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464
JBrowse link
G Slc28a2 solute carrier family 28 member 2 increases transport ISO SLC28A2 protein results in increased transport of Adenosine CTD PMID:10087507 NCBI chr 3:109,324,815...109,387,702
Ensembl chr 3:109,366,996...109,387,702
JBrowse link
G Slc29a1 solute carrier family 29 member 1 multiple interactions
increases uptake
affects abundance
ISO
EXP
4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; 4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; [4-nitrobenzylthioinosine results in decreased activity of SLC29A1 protein] inhibits the reaction [Oxygen deficiency results in increased abundance of Adenosine]; [SLC29A1 co-treated with Oxygen deficiency] affects the abundance of Adenosine; Dipyridamole inhibits the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; Dipyridamole inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Dipyridamole promotes the reaction [[SLC29A1 co-treated with Oxygen deficiency] affects the abundance of Adenosine]
SLC29A1 protein alternative form results in increased uptake of Adenosine; SLC29A1 protein results in increased uptake of Adenosine
cilostazol inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Dipyridamole inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; draflazine inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Ethanol promotes the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; Ethanol promotes the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Ticagrelor inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]
Adenosine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine]
SLC29A1 affects the abundance of Adenosine
CTD PMID:9353301 PMID:9396714 PMID:11179696 PMID:21283641 PMID:21872611 More... NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link
G Slc29a2 solute carrier family 29 member 2 increases uptake ISO SLC29A2 protein results in increased uptake of Adenosine CTD PMID:9396714 NCBI chr 1:202,327,641...202,335,185
Ensembl chr 1:202,327,354...202,335,171
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Adenosine CTD PMID:19164483 NCBI chr20:28,645,265...28,685,388
Ensembl chr20:28,647,391...28,685,388
JBrowse link
G Slc5a5 solute carrier family 5 member 5 increases expression EXP Adenosine results in increased expression of SLC5A5 mRNA; Adenosine results in increased expression of SLC5A5 protein CTD PMID:16954431 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
JBrowse link
G Tlr4 toll-like receptor 4 increases expression
affects localization
multiple interactions
ISO Adenosine results in increased expression of TLR4 mRNA
Adenosine affects the localization of TLR4 protein
Adenosine promotes the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of TLR4 protein]
CTD PMID:21538184 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine inhibits the reaction [Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]; [Adenosine co-treated with Homocysteine co-treated with TNF protein] results in increased cleavage of RIPK1 protein; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein affects the localization of RELA protein modified form]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of RELA protein]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; [Adenosine co-treated with Homocysteine] results in increased susceptibility to TNF protein; Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF mRNA]; Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]; ZM 241385 inhibits the reaction [Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]
Adenosine results in decreased expression of TNF protein
CTD PMID:11023991 PMID:21538184 PMID:24224954 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions ISO [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; [Adenosine co-treated with Homocysteine] results in decreased expression of TNFAIP3 mRNA; [Adenosine co-treated with Homocysteine] results in decreased expression of TNFAIP3 protein CTD PMID:24224954 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Adenosine co-treated with Coformycin] results in decreased expression of TNFSF10 mRNA CTD PMID:11992407 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO Adenosine promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Upp1 uridine phosphorylase 1 increases metabolic processing ISO UPP1 protein results in increased metabolism of Adenosine CTD PMID:15772079 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
increases secretion
ISO Adenosine promotes the reaction [Dipyridamole results in increased secretion of VEGFA protein]
Adenosine results in increased expression of VEGFA mRNA
Adenosine results in increased secretion of VEGFA protein
CTD PMID:20067761 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
adenosine 3',5'-bismonophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions EXP Glutathione Disulfide affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]; Glutathione Disulfide affects the reaction [Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]]; Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein] CTD PMID:21130751 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions ISO [2,2',4,4'-tetrabromodiphenyl ether metabolite co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; [Estradiol co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; [tetrabromobisphenol A co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; Estradiol inhibits the reaction [[tetrabromobisphenol A co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein]; tetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein] CTD PMID:23959441 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 affects binding
multiple interactions
ISO adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein
Benzoquinones analog inhibits the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein]; Dehydroepiandrosterone inhibits the reaction [Benzoquinones analog inhibits the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein]]
CTD PMID:24059442 NCBI chr 1:75,451,178...75,508,142 JBrowse link
adenosine 5'-(hexahydrogen pentaphosphate) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt11 nudix hydrolase 11 multiple interactions ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of adenosine 5'-pentaphosphate CTD PMID:12121577 NCBI chr  X:16,326,775...16,333,396
Ensembl chr  X:16,326,598...16,333,145
JBrowse link
adenosine 5'-[gamma-thio]triphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd80 Cd80 molecule increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of CD80 protein CTD PMID:15944274 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of CD86 protein CTD PMID:15944274 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Il10 interleukin 10 decreases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in decreased expression of IL10 protein CTD PMID:15944274 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12b interleukin 12B increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL12B protein CTD PMID:15944274 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1b interleukin 1 beta increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL1B protein CTD PMID:15944274 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G LOC102552569 P2Y purinoceptor 11-like multiple interactions ISO [adenosine 5'-O-(3-thiotriphosphate) binds to and results in increased activity of P2RY11 protein] which results in increased expression of CXCL8 protein; adenosine 5'-O-(3-thiotriphosphate) binds to and results in increased activity of P2RY11 protein CTD PMID:19815812
G P2rx7 purinergic receptor P2X 7 affects response to substance ISO P2RX7 protein affects the susceptibility to adenosine 5'-O-(3-thiotriphosphate) CTD PMID:12873706 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO adenosine 5'-O-(3-thiotriphosphate) inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr15:17,360,304...17,367,679 JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity
multiple interactions
EXP adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein
Capsaicin promotes the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]
CTD PMID:11140687 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
adenosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 multiple interactions ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions ISO [4-dimethylaminocinnamaldehyde co-treated with Adenosine Monophosphate] binds to ALDH1A1 protein CTD PMID:10609638 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor increases abundance ISO ERCC6 gene mutant form results in increased abundance of Adenosine Monophosphate CTD PMID:25440059 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Nudt11 nudix hydrolase 11 multiple interactions ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate; [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:16,326,775...16,333,396
Ensembl chr  X:16,326,598...16,333,145
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Adenosine Monophosphate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Tp73 tumor protein p73 affects abundance ISO TP73 protein affects the abundance of Adenosine Monophosphate CTD PMID:25554796 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
ADP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
affects binding
ISO estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein mutant form]; estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein]; Vanadates promotes the reaction [Adenosine Diphosphate binds to ABCC1 protein]
Adenosine Diphosphate binds to ABCC1 protein; Adenosine Diphosphate binds to ABCC1 protein mutant form
CTD PMID:18336795 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions EXP Adenosine Diphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ak1 adenylate kinase 1 increases abundance ISO AK1 protein results in increased abundance of Adenosine Diphosphate CTD PMID:11390963 NCBI chr 3:15,912,431...15,923,045 JBrowse link
G Alb albumin decreases secretion
multiple interactions
ISO Adenosine Diphosphate results in decreased secretion of ALB protein
Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of ALB protein]
CTD PMID:17303692 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Axl Axl receptor tyrosine kinase decreases response to substance ISO AXL protein results in decreased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Cat catalase multiple interactions EXP CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein] CTD PMID:16781456 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cd40lg CD40 ligand increases expression
multiple interactions
ISO Adenosine Diphosphate results in increased expression of CD40LG protein
clopidogrel inhibits the reaction [Adenosine Diphosphate results in increased expression of CD40LG protein]
CTD PMID:11297035 PMID:17043144 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Adenosine Diphosphate binds to and results in decreased activity of CFTR protein; P(1),P(5)-di(adenosine-5'-)pentaphosphate inhibits the reaction [Adenosine Diphosphate binds to and results in decreased activity of CFTR protein] CTD PMID:15684079 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 multiple interactions ISO Adenosine Diphosphate binds to and affects the folding of CHORDC1 protein; Adenosine Diphosphate promotes the reaction [CHORDC1 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein] CTD PMID:23184943 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO CYP2C19 gene affects the susceptibility to [Adenosine Diphosphate co-treated with clopidogrel]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; CYP2C19 gene SNP affects the susceptibility to [Adenosine Diphosphate co-treated with Arachidonic Acid] CTD PMID:16772608 PMID:18004210 PMID:18394438 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Dtymk deoxythymidylate kinase multiple interactions ISO DTYMK protein binds to [N1-(4-bis(pivaloyloxymethyl)phosphinylbuten-2-yl)thymine co-treated with Adenosine Diphosphate] CTD PMID:21128666 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO Adenosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP1 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP1 protein]] CTD PMID:32941855 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO Adenosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP6 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP6 protein]] CTD PMID:32941855 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Epha4 Eph receptor A4 increases phosphorylation
multiple interactions
ISO Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein
Benzoic Acid analog inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein]
CTD PMID:22273509 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
decreases activity
ISO Adenosine Diphosphate inhibits the reaction [ERN1 protein binds to ERN1 protein]
Adenosine Diphosphate results in decreased activity of ERN1 protein
CTD PMID:25164867 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G F2 coagulation factor II increases abundance
multiple interactions
ISO F2 protein results in increased abundance of Adenosine Diphosphate
Quercetin inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]; resveratrol inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]
CTD PMID:15342215 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fga fibrinogen alpha chain multiple interactions
increases secretion
ISO Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGA protein] CTD PMID:17303692 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain decreases secretion
multiple interactions
ISO Adenosine Diphosphate results in decreased secretion of FGB protein
Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of FGB protein]
CTD PMID:17303692 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgg fibrinogen gamma chain increases secretion
multiple interactions
ISO Adenosine Diphosphate results in increased secretion of FGG protein
Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGG protein]
CTD PMID:17303692 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO Adenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog] CTD PMID:15788719 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gas6 growth arrest specific 6 increases response to substance ISO GAS6 protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]; U 0126 inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]] CTD PMID:32941855 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO Adenosine Diphosphate binds to and affects the folding of HRAS protein CTD PMID:16388579 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Adenosine Diphosphate] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO Adenosine Diphosphate results in increased expression of IL6 protein
MRS 2211 inhibits the reaction [Adenosine Diphosphate results in increased expression of IL6 protein]
CTD PMID:24849676 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Adenosine Diphosphate] CTD PMID:16214444 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itga2b integrin subunit alpha 2b multiple interactions ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
JBrowse link
G Itgb1bp2 integrin subunit beta 1 binding protein 2 multiple interactions ISO Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to ITGB1BP2 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr  X:66,572,537...66,577,174
Ensembl chr  X:66,572,537...66,577,174
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Adenosine Diphosphate results in increased phosphorylation of MAPK1 protein
Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK1 protein]]
CTD PMID:15034929 PMID:32941855 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO Adenosine Diphosphate results in increased phosphorylation of MAPK3 protein
Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK3 protein]]
CTD PMID:15034929 PMID:32941855 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein] CTD PMID:24466103 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK9 protein] CTD PMID:24466103 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase increases response to substance ISO MERTK protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO NOS2 protein affects the susceptibility to [Phenylephrine co-treated with Adenosine Diphosphate] CTD PMID:11498454 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nt5e 5' nucleotidase, ecto decreases activity ISO Adenosine Diphosphate analog results in decreased activity of NT5E protein CTD PMID:18404487 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
JBrowse link
G P2ry12 purinergic receptor P2Y12 affects response to substance
increases response to substance
multiple interactions
ISO
EXP
P2RY12 gene polymorphism affects the susceptibility to Adenosine Diphosphate; P2RY12 protein affects the susceptibility to Adenosine Diphosphate
P2RY12 protein results in increased susceptibility to Adenosine Diphosphate
Epinephrine inhibits the reaction [P2RY12 gene mutant form results in decreased susceptibility to Adenosine Diphosphate]
P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]
CTD PMID:11196645 PMID:11413167 PMID:18404433 PMID:23849096 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361
JBrowse link
G Pdgfb platelet derived growth factor subunit B increases secretion
multiple interactions
ISO Adenosine Diphosphate results in increased secretion of PDGFB protein
Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of PDGFB protein]
CTD PMID:17303692 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pf4 platelet factor 4 increases secretion ISO Adenosine Diphosphate results in increased secretion of PF4 protein CTD PMID:19428933 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Pfkm phosphofructokinase, muscle multiple interactions ISO Adenosine Diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein] CTD PMID:23454376 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pgp phosphoglycolate phosphatase decreases phosphorylation ISO PGP protein results in decreased phosphorylation of Adenosine Diphosphate CTD PMID:24338473 NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858
JBrowse link
G Ppbp pro-platelet basic protein increases secretion ISO Adenosine Diphosphate results in increased secretion of PPBP protein CTD PMID:19428933 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit multiple interactions ISO Adenosine Diphosphate binds to and affects the folding of PPP5C protein CTD PMID:23184943 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 increases glutathionylation
multiple interactions
EXP Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein
CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein]
CTD PMID:16781456 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Selp selectin P multiple interactions
increases expression
ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; Heparin promotes the reaction [Adenosine Diphosphate affects the localization of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]]; P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; Quercetin inhibits the reaction [Adenosine Diphosphate results in increased expression of SELP protein] CTD PMID:9740346 PMID:18394438 PMID:18404433 PMID:23249183 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Sirt3 sirtuin 3 decreases abundance ISO SIRT3 protein results in decreased abundance of Adenosine Diphosphate CTD PMID:23166782 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
JBrowse link
G Taldo1 transaldolase 1 increases abundance ISO TALDO1 gene mutant form results in increased abundance of Adenosine Diphosphate CTD PMID:19436114 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
JBrowse link
G Thbs1 thrombospondin 1 increases secretion ISO Adenosine Diphosphate results in increased secretion of THBS1 protein CTD PMID:17303692 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]; U 0126 inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]] CTD PMID:32941855 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase increases response to substance ISO TYRO3 protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein increases phosphorylation
multiple interactions
ISO Adenosine Diphosphate results in increased phosphorylation of VASP protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of VASP protein]
CTD PMID:25329809 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
ADP-D-ribose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adprh ADP-ribosylarginine hydrolase increases hydrolysis ISO ADPRH protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite CTD PMID:21498885 NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931
JBrowse link
G Adprs ADP-ribosylserine hydrolase increases hydrolysis
multiple interactions
ISO ADPRS protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite
Adenosine Diphosphate Ribose inhibits the reaction [ADPRS protein results in increased hydrolysis of O-Acetyl-ADP-Ribose]
CTD PMID:21498885 NCBI chr 5:138,614,022...138,619,296
Ensembl chr 5:138,614,022...138,619,296
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions ISO NOS1 protein affects the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased ribosylation of Adenosine Diphosphate Ribose] CTD PMID:10318960 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions
increases activity
EXP
ISO
Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]; Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Flufenamic Acid inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]
Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein
2-aminoethoxydiphenyl borate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Copper Sulfate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; ferrous chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; lead nitrate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Mercuric Chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Miconazole inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Selenium Oxides inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]
4-amylcinnamoylanthranilic acid inhibits the reaction [[Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; [Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein; Glutathione inhibits the reaction [[Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein]; Glutathione inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; TRPM2 protein promotes the reaction [Adenosine Diphosphate Ribose results in increased uptake of Calcium]
CTD PMID:18204483 PMID:20878536 PMID:21900507 PMID:22750002 PMID:33309544 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
JBrowse link
aldehydo-D-ribose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression
ISO [Ribose co-treated with Glucose] results in increased expression of AGER protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]
Ribose results in increased expression of AGER protein
CTD PMID:30101366 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G B2m beta-2 microglobulin increases glycation ISO Ribose results in increased glycation of B2M protein CTD PMID:21864514 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Creatine co-treated with Ribose] results in decreased activity of CASP3 protein CTD PMID:21220914 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases phosphorylation ISO Ribose results in increased phosphorylation of CHUK protein CTD PMID:30101366 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases phosphorylation ISO Ribose results in increased phosphorylation of IKBKB protein CTD PMID:30101366 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases phosphorylation
ISO [Ribose co-treated with Glucose] results in increased phosphorylation of NFKBIA protein
Ribose results in increased phosphorylation of NFKBIA protein
CTD PMID:30101366 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP Ribose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
multiple interactions
ISO Ribose results in increased phosphorylation of RELA protein
[Ribose co-treated with Glucose] affects the localization of RELA protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]; Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]
CTD PMID:30101366 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
AMP-PNP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions EXP Adenylyl Imidodiphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Cftr CF transmembrane conductance regulator affects activity ISO Adenylyl Imidodiphosphate affects the activity of CFTR protein CTD PMID:15657297 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO Adenylyl Imidodiphosphate inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr15:17,360,304...17,367,679 JBrowse link
arachidonoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
ATP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO Adenosine Triphosphate affects the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide] CTD PMID:12379217 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO
EXP
Adenosine Triphosphate promotes the reaction [ABCB11 protein results in increased uptake of fexofenadine] CTD PMID:18245269 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
affects binding
increases hydrolysis
ISO
EXP
[Cobalt results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; [Magnesium results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; [Manganese results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; ABCB1 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; aurapten promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; crizotinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; lapatinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; nobiletin promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]
Adenosine Triphosphate binds to ABCB1 protein
[Rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of Adenosine Triphosphate
CTD PMID:2900677 PMID:14978246 PMID:18829547 PMID:18955043 PMID:22233293 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
affects activity
increases hydrolysis
affects binding
ISO [Adenosine Triphosphate affects the activity of ABCC1 protein] which results in increased transport of Acetaminophen metabolite; ABCC1 protein binds to and results in increased degradation of Adenosine Triphosphate; ABCC1 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; ABCC1 protein mutant form binds to and results in increased hydrolysis of Adenosine Triphosphate; Adenosine Triphosphate binds to and affects the folding of ABCC1 protein; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of Bilirubin]; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of estradiol-17 beta-glucuronide]; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of Leukotriene C4]; daidzein promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; hesperetin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; naringenin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; nobiletin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Resveratrol promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]
Daunorubicin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Vanadates inhibits the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]
Adenosine Triphosphate binds to ABCC1 protein
CTD PMID:10856430 PMID:11278000 PMID:14978246 PMID:15245331 PMID:15355964 More... NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
affects activity
affects metabolic processing
EXP
ISO
Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased secretion of Fluo-3]; Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of temocaprilat]
Adenosine Triphosphate affects the activity of ABCC2 protein
[Adenosine Triphosphate affects the activity of ABCC2 protein] which results in increased transport of Acetaminophen metabolite; [Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; Adenosine Triphosphate affects the reaction [ABCC2 protein results in increased transport of Mercury]; verlukast inhibits the reaction [[Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide]
ABCC2 protein affects the metabolism of Adenosine Triphosphate
Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of S-1,2-dichlorovinyl-N-acetylcysteine]
CTD PMID:9067317 PMID:9794919 PMID:20060011 PMID:22027652 PMID:24039982 More... NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO Adenosine Triphosphate promotes the reaction [ABCC3 protein affects the transport of fexofenadine] CTD PMID:18245269 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
affects activity
increases hydrolysis
ISO [Adenosine Triphosphate affects the activity of ABCC4 protein] which results in increased transport of Acetaminophen metabolite; ABCC4 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; daidzein promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; hesperetin promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; naringenin promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin affects the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin inhibits the reaction [Alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]]; Resveratrol promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [Alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]] CTD PMID:14978246 PMID:16156793 PMID:32472168 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 affects binding ISO Adenosine Triphosphate binds to ABCC6 protein CTD PMID:11880368 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 multiple interactions EXP Adenosine Triphosphate deficiency inhibits the reaction [Estradiol inhibits the reaction [Glyburide binds to ABCC8 protein]] CTD PMID:19095654 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 multiple interactions EXP
ISO
Adenosine Triphosphate results in decreased activity of [KCNJ8 protein binds to ABCC9 protein]
Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]]
CTD PMID:11390963 PMID:28842488 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases hydrolysis
multiple interactions
ISO ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate
[Adenosine Triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate; Lapatinib promotes the reaction [ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate]; Sulfasalazine inhibits the reaction [[Adenosine Triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate]
CTD PMID:18829547 PMID:32003934 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein] CTD PMID:19366808 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions ISO [ACSL5 protein affects the susceptibility to Palmitic Acid] which affects the abundance of Adenosine Triphosphate CTD PMID:32347412 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein]; [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA; [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein; Adenosine Triphosphate promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; Adenosine Triphosphate promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein]; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ACTA2 mRNA]; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ACTA2 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein]; L 709049 inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; L 709049 inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein] CTD PMID:32721574 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases secretion EXP ADCYAP1 protein results in increased secretion of Adenosine Triphosphate CTD PMID:18563302 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
decreases expression
EXP Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein; ARRB2 protein affects the reaction [Adenosine Triphosphate results in decreased activity of AGTR1A protein]; CABIN1 protein inhibits the reaction [Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein]; Cyclosporine inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A protein] CTD PMID:21464294 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions EXP Adenosine Triphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases activity
multiple interactions
ISO Adenosine Triphosphate results in decreased activity of AKT1 protein
Alcohols inhibits the reaction [Adenosine Triphosphate results in decreased activity of AKT1 protein]
CTD PMID:24300283 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 increases abundance ISO ALDH5A1 gene mutant form results in increased abundance of Adenosine Triphosphate CTD PMID:29031482 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
JBrowse link
G Alk ALK receptor tyrosine kinase affects binding
multiple interactions
ISO ALK protein binds to Adenosine Triphosphate
[ALK protein mutant form promotes the reaction [ALK protein binds to Adenosine Triphosphate]] which results in decreased susceptibility to crizotinib; ALK protein mutant form promotes the reaction [ALK protein binds to Adenosine Triphosphate]
CTD PMID:22072639 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases response to substance
multiple interactions
ISO ALPL gene mutant form results in increased susceptibility to Adenosine Triphosphate
ALPL gene mutant form promotes the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]
CTD PMID:27466191 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Anxa1 annexin A1 multiple interactions EXP [Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein; arsenite affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; Cadmium affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; chromium hexavalent ion affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; Lead affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein] CTD PMID:20655937 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases secretion
ISO Adenosine Triphosphate inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form]; Adenosine Triphosphate inhibits the reaction [Rotenone results in decreased secretion of APP protein modified form]; Rotenone inhibits the reaction [Adenosine Triphosphate results in increased secretion of APP protein modified form]; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased secretion of APP protein modified form] CTD PMID:22906069 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions EXP Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]]; ARRB2 protein affects the reaction [Adenosine Triphosphate results in decreased activity of AGTR1A protein] CTD PMID:21464294 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Asic1 acid sensing ion channel subunit 1 multiple interactions EXP [Acids binds to and affects the activity of ASIC1 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
JBrowse link
G Asic2 acid sensing ion channel subunit 2 multiple interactions EXP [Acids binds to and affects the activity of ASIC2 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424
JBrowse link
G Asic3 acid sensing ion channel subunit 3 multiple interactions EXP [Acids binds to and affects the activity of ASIC3 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr 4:10,760,509...10,764,987
Ensembl chr 4:10,760,597...10,764,643
JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions ISO [Copper co-treated with Adenosine Triphosphate] results in increased phosphorylation of ATP7A protein CTD PMID:20964302 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Atp7b ATPase copper transporting beta multiple interactions
increases phosphorylation
ISO [Copper co-treated with Adenosine Triphosphate] results in increased phosphorylation of ATP7B protein
Adenosine Triphosphate results in increased phosphorylation of ATP7B protein
CTD PMID:19405516 PMID:20964302 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases hydrolysis EXP ATP8B1 protein results in increased hydrolysis of Adenosine Triphosphate CTD PMID:11584374 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Avp arginine vasopressin multiple interactions
increases secretion
EXP Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of AVP protein]; bisindolylmaleimide I inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; Dactinomycin inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of AVP protein] CTD PMID:11102496 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Adenosine Triphosphate binds to P2RY11 protein] which results in decreased expression of BCL2 protein CTD PMID:21503959 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcr BCR activator of RhoGEF and GTPase multiple interactions ISO [BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein] CTD PMID:19366808 NCBI chr20:13,471,679...13,596,497
Ensembl chr20:13,471,668...13,597,016
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases abundance ISO BIRC5 protein results in increased abundance of Adenosine Triphosphate CTD PMID:32497533 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Cabin1 calcineurin binding protein 1 multiple interactions EXP CABIN1 protein inhibits the reaction [Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein] CTD PMID:21464294 NCBI chr20:12,893,314...13,015,357
Ensembl chr20:12,893,358...13,015,357
JBrowse link
G Calca calcitonin-related polypeptide alpha increases secretion
multiple interactions
EXP Adenosine Triphosphate results in increased secretion of CALCA protein
Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]; Flurbiprofen inhibits the reaction [Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]]; Suramin inhibits the reaction [Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]]
CTD PMID:12044622 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Casp1 caspase 1 increases activity
multiple interactions
EXP
ISO
Adenosine Triphosphate results in increased activity of CASP1 mRNA; Adenosine Triphosphate results in increased activity of CASP1 protein
[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP1 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP1 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]; fraxinellone inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; MCC-950 inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP1 mRNA]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP1 protein]
[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [PML protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; [Niclosamide co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CASP1 protein; Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP1 protein]; Arsenic Trioxide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; MCC-950 inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]
CTD PMID:18604214 PMID:19130485 PMID:21832250 PMID:23430110 PMID:24149798 More... NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
ISO Adenosine Triphosphate results in increased expression of CASP3
Suramin inhibits the reaction [Adenosine Triphosphate results in increased expression of CASP3]
CTD PMID:19448140 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 multiple interactions ISO [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP4 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP4 protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP4 mRNA]; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP4 protein]
Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP4 protein]
CTD PMID:24149798 PMID:25288807 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Cat catalase increases expression ISO Adenosine Triphosphate results in increased expression of CAT mRNA CTD PMID:22129738 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases secretion
multiple interactions
ISO Adenosine Triphosphate results in increased secretion of CCL3 protein
azetidine inhibits the reaction [Adenosine Triphosphate results in increased secretion of CCL3 protein]
CTD PMID:26522449 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides]]; [Phosphatidylinositol 4,5-Diphosphate co-treated with Adenosine Triphosphate] results in increased activity of CFTR protein; Adenosine Triphosphate affects the reaction [Curcumin results in increased activity of CFTR protein mutant form]; Adenosine Triphosphate binds to and results in increased activity of CFTR protein; Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides] CTD PMID:14710196 PMID:15623556 PMID:17178710 PMID:20675434 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 multiple interactions ISO Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to PPP5C protein]; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to SUGT1 protein]
Adenosine Triphosphate binds to and affects the folding of CHORDC1 protein; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to CHORDC1 protein]; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to HSP90AA1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]
CTD PMID:23184943 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Esche