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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nickel molecular entity
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Accession:CHEBI:33748 term browser browse the term
Synonyms:related_synonym: nickel compounds;   nickel molecular entities



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nickel dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO nickel chloride results in increased expression of ABCA1 mRNA CTD PMID:17312168 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases response to substance
increases expression
multiple interactions
EXP ABCB1 protein results in decreased susceptibility to nickel chloride
nickel chloride results in increased expression of ABCB1 mRNA; nickel chloride results in increased expression of ABCB1 protein
alpha-Tocopherol inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]; fumonisin B1 inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein]
CTD PMID:24448832 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression EXP nickel chloride results in increased expression of ABCC1 mRNA CTD PMID:22110744 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO nickel chloride results in increased expression of ABCG1 mRNA CTD PMID:17312168 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abtb1 ankyrin repeat and BTB domain containing 1 affects expression EXP nickel chloride affects the expression of ABTB1 mRNA CTD PMID:22546817 NCBI chr 4:121,299,302...121,305,667
Ensembl chr 4:121,299,304...121,305,620
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO nickel chloride results in decreased expression of ACADM mRNA CTD PMID:17312168 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression ISO nickel chloride results in increased expression of ACKR3 mRNA CTD PMID:17312168 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
JBrowse link
G Acly ATP citrate lyase affects expression EXP nickel chloride affects the expression of ACLY mRNA CTD PMID:22546817 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Aco1 aconitase 1 decreases activity
increases activity
multiple interactions
ISO nickel chloride results in decreased activity of ACO1 protein
nickel chloride results in increased activity of ACO1 protein
[nickel chloride results in increased activity of ACO1 protein] inhibits the reaction [ferrous sulfate results in increased expression of FTL protein]; [nickel chloride results in increased activity of ACO1 protein] which results in increased expression of and results in increased stability of TFRC mRNA; Iron inhibits the reaction [nickel chloride results in increased activity of ACO1 protein]
CTD PMID:16039939 PMID:16649251 PMID:17018869 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 decreases activity ISO nickel chloride results in decreased activity of ACO2 protein CTD PMID:17018869 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression ISO nickel chloride results in decreased expression of ACOX1 mRNA CTD PMID:17312168 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 affects expression EXP nickel chloride affects the expression of ACSF2 mRNA CTD PMID:22110744 NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression
affects expression
ISO
EXP
nickel chloride results in decreased expression of ACSL1 mRNA
nickel chloride affects the expression of ACSL1 mRNA
CTD PMID:17547211 PMID:22110744 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
ISO nickel chloride results in increased expression of ACTA2 mRNA; nickel chloride results in increased expression of ACTA2 protein
sodium bisulfide inhibits the reaction [nickel chloride results in increased expression of ACTA2 mRNA]; sodium bisulfide inhibits the reaction [nickel chloride results in increased expression of ACTA2 protein]
CTH gene mutant form promotes the reaction [nickel chloride results in increased expression of ACTA2 protein]
CTD PMID:30055191 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actb actin, beta decreases expression
increases expression
ISO nickel chloride results in decreased expression of ACTB protein
nickel chloride results in increased expression of ACTB mRNA
CTD PMID:20452446 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actn2 actinin alpha 2 affects expression EXP nickel chloride affects the expression of ACTN2 mRNA CTD PMID:22546817 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 affects expression EXP nickel chloride affects the expression of ADAM17 mRNA CTD PMID:22546817 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 multiple interactions
decreases activity
EXP
ISO
nickel chloride inhibits the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]
nickel chloride results in decreased activity of ADCYAP1 protein
CTD PMID:18198219 PMID:22009744 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Adm adrenomedullin increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of ADM mRNA
nickel chloride affects the expression of ADM mRNA
CTD PMID:17312168 PMID:17547211 PMID:21455298 PMID:22110744 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Afp alpha-fetoprotein affects expression EXP nickel chloride affects the expression of AFP mRNA CTD PMID:22110744 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects expression EXP nickel chloride affects the expression of AIFM1 mRNA CTD PMID:22546817 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 affects expression EXP nickel chloride affects the expression of AIFM2 mRNA CTD PMID:22546817 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 decreases expression ISO nickel chloride results in decreased expression of AIMP1 mRNA CTD PMID:17312168 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
JBrowse link
G Aipl1 aryl hydrocarbon receptor-interacting protein-like 1 affects expression EXP nickel chloride affects the expression of AIPL1 mRNA CTD PMID:22546817 NCBI chr10:56,655,693...56,664,922
Ensembl chr10:56,655,693...56,664,922
JBrowse link
G Ak1 adenylate kinase 1 affects expression EXP nickel chloride affects the expression of AK1 mRNA CTD PMID:22546817 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041
JBrowse link
G Ak3 adenylate kinase 3 increases expression ISO nickel chloride results in increased expression of AK3 mRNA CTD PMID:17312168 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
JBrowse link
G Ak4 adenylate kinase 4 increases expression
affects expression
multiple interactions
ISO
EXP
nickel chloride results in increased expression of AK4 mRNA
nickel chloride affects the expression of AK4 mRNA
HIF1A affects the reaction [nickel chloride results in increased expression of AK4 mRNA]
CTD PMID:12729255 PMID:22110744 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Akap11 A-kinase anchoring protein 11 decreases expression ISO nickel chloride results in decreased expression of AKAP11 mRNA CTD PMID:17312168 NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 decreases expression ISO nickel chloride results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 affects expression EXP nickel chloride affects the expression of AKR1B8 mRNA CTD PMID:22110744 NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 affects expression EXP nickel chloride affects the expression of AKR1D1 mRNA CTD PMID:22110744 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases response to substance
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [nickel chloride results in increased phosphorylation of AKT1 protein]; [nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of AKT1 protein; [nickel chloride results in increased phosphorylation of AKT1 protein] which results in decreased activity of and results in increased phosphorylation of GSK3B protein; nickel chloride promotes the reaction [Tretinoin results in increased phosphorylation of AKT1 protein]
AKT1 protein results in decreased susceptibility to nickel chloride
AKT1 protein affects the reaction [nickel chloride results in increased expression of HIF1A protein]; AKT1 protein affects the reaction [nickel chloride results in increased expression of NDRG1 protein]
CTD PMID:14729612 PMID:21837363 PMID:23828460 PMID:25614230 PMID:30724446 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 affects expression EXP nickel chloride affects the expression of AKT2 mRNA CTD PMID:22546817 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Alb albumin multiple interactions EXP [sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate co-treated with Mercuric Chloride co-treated with chromium trioxide co-treated with nickel chloride co-treated with manganese chloride co-treated with ferric chloride] results in decreased expression of ALB protein CTD PMID:17657459 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression
increases expression
ISO nickel chloride results in decreased expression of ALDH1A1 mRNA
nickel chloride results in increased expression of ALDH1A1 protein
CTD PMID:12729255 PMID:14645679 PMID:26962057 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 affects expression EXP nickel chloride affects the expression of ALDH1B1 mRNA CTD PMID:22110744 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions
affects expression
ISO
EXP
nickel chloride inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]
nickel chloride affects the expression of ALDH3A1 mRNA
CTD PMID:14645679 PMID:22110744 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A multiple interactions
increases expression
ISO HIF1A affects the reaction [nickel chloride results in increased expression of ALDOA mRNA] CTD PMID:12426141 PMID:12839937 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Amacr alpha-methylacyl-CoA racemase affects expression EXP nickel chloride affects the expression of AMACR mRNA CTD PMID:22110744 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 affects expression EXP nickel chloride affects the expression of AMPD3 mRNA CTD PMID:22110744 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
JBrowse link
G Anapc4 anaphase promoting complex subunit 4 affects expression EXP nickel chloride affects the expression of ANAPC4 mRNA CTD PMID:22546817 NCBI chr14:58,125,995...58,159,253
Ensembl chr14:58,125,995...58,157,770
JBrowse link
G Anapc7 anaphase promoting complex subunit 7 affects expression EXP nickel chloride affects the expression of ANAPC7 mRNA CTD PMID:22546817 NCBI chr12:34,131,214...34,160,819
Ensembl chr12:34,133,429...34,160,005
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression
multiple interactions
ISO nickel chloride results in increased expression of ANGPTL4 mRNA
[nickel chloride results in increased abundance of Nickel] which results in decreased methylation of ANGPTL4 promoter; [nickel chloride results in increased abundance of Nickel] which results in increased expression of ANGPTL4 mRNA; [nickel chloride results in increased abundance of Nickel] which results in increased expression of ANGPTL4 protein; TET1 protein affects the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ANGPTL4 mRNA]; TET1 protein affects the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of ANGPTL4 protein]
CTD PMID:17312168 PMID:21455298 PMID:34571076 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ankrd37 ankyrin repeat domain 37 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of ANKRD37 mRNA
nickel chloride affects the expression of ANKRD37 mRNA
CTD PMID:21455298 PMID:22110744 NCBI chr16:46,269,025...46,271,971
Ensembl chr16:46,268,443...46,271,963
JBrowse link
G Anxa2 annexin A2 affects expression
increases expression
EXP
ISO
nickel chloride affects the expression of ANXA2 mRNA
nickel chloride results in increased expression of ANXA2 protein
CTD PMID:11250053 PMID:22110744 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 affects expression EXP nickel chloride affects the expression of APBB1 mRNA CTD PMID:22546817 NCBI chr 1:159,896,889...159,920,505
Ensembl chr 1:159,896,880...159,920,627
JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 affects expression EXP nickel chloride affects the expression of APBB2 mRNA CTD PMID:22546817 NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495
JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 affects expression EXP nickel chloride affects the expression of APBB3 mRNA CTD PMID:22546817 NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
JBrowse link
G Apc APC regulator of WNT signaling pathway affects expression EXP nickel chloride affects the expression of APC mRNA CTD PMID:22546817 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 affects expression EXP nickel chloride affects the expression of APEX2 mRNA CTD PMID:22546817 NCBI chr  X:19,425,684...19,508,459
Ensembl chr  X:19,487,419...19,508,439
JBrowse link
G Apln apelin affects expression EXP nickel chloride affects the expression of APLN mRNA CTD PMID:22110744 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391
JBrowse link
G Apol2 apolipoprotein L, 2 increases expression ISO nickel chloride results in increased expression of APOL2 mRNA CTD PMID:21455298 NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558
JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase affects expression EXP nickel chloride affects the expression of ARAF mRNA CTD PMID:22546817 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073
JBrowse link
G Arg1 arginase 1 affects expression EXP nickel chloride affects the expression of ARG1 mRNA CTD PMID:22546817 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 affects expression EXP nickel chloride affects the expression of ARHGEF6 mRNA CTD PMID:22546817 NCBI chr  X:135,145,447...135,264,636
Ensembl chr  X:135,146,786...135,275,304
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 affects expression EXP nickel chloride affects the expression of ARL6IP1 mRNA CTD PMID:22110744 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO HIF1A affects the reaction [nickel chloride results in increased expression of ARNT mRNA]
nickel chloride promotes the reaction [HIF1A protein binds to ARNT protein]
CTD PMID:12729255 PMID:29355601 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Arrb2 arrestin, beta 2 affects localization ISO nickel chloride affects the localization of ARRB2 protein CTD PMID:16959833 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Arrdc4 arrestin domain containing 4 increases expression ISO nickel chloride results in increased expression of ARRDC4 mRNA CTD PMID:21455298 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
JBrowse link
G Asic2 acid sensing ion channel subunit 2 affects expression EXP nickel chloride affects the expression of ASIC2 mRNA CTD PMID:22546817 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424
JBrowse link
G Asl argininosuccinate lyase affects expression EXP nickel chloride affects the expression of ASL mRNA CTD PMID:22110744 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO nickel chloride results in increased expression of ASNS mRNA CTD PMID:17312168 PMID:17547211 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO [nickel chloride results in increased expression of GADD45A protein] which results in decreased phosphorylation of ATF2 protein CTD PMID:23536762 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf3 activating transcription factor 3 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of ATF3 mRNA
nickel chloride affects the expression of ATF3 mRNA
CTD PMID:17312168 PMID:22110744 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atm ATM serine/threonine kinase increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of ATM mRNA
nickel chloride affects the expression of ATM mRNA
CTD PMID:12426141 PMID:12839937 PMID:22546817 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression ISO nickel chloride results in decreased expression of ATP2A2 mRNA CTD PMID:17312168 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Aurka aurora kinase A affects expression EXP nickel chloride affects the expression of AURKA mRNA CTD PMID:22546817 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding affects expression EXP nickel chloride affects the expression of AZGP1 mRNA CTD PMID:22110744 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression ISO nickel chloride results in increased expression of BACH1 mRNA CTD PMID:17312168 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
affects expression
EXP nickel chloride results in increased expression of BAD protein
nickel chloride affects the expression of BAD mRNA
CTD PMID:20391133 PMID:22546817 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag1 BAG cochaperone 1 affects expression EXP nickel chloride affects the expression of BAG1 mRNA CTD PMID:22546817 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bag3 BAG cochaperone 3 affects expression EXP nickel chloride affects the expression of BAG3 mRNA CTD PMID:22546817 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression
affects expression
EXP nickel chloride results in increased expression of BAK1 mRNA
nickel chloride affects the expression of BAK1 mRNA
CTD PMID:21843586 PMID:22546817 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
affects expression
EXP
ISO
nickel chloride results in increased expression of BAX protein
[nickel chloride results in increased abundance of Nickel] which results in increased expression of BAX protein; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of BAX protein]
nickel chloride affects the expression of BAX mRNA
CTD PMID:20391133 PMID:22546817 PMID:31943712 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression
affects expression
multiple interactions
ISO
EXP
nickel chloride results in increased expression of BBC3 mRNA
nickel chloride affects the expression of BBC3 mRNA
TP53 protein affects the reaction [nickel chloride results in increased expression of BBC3 mRNA]
CTD PMID:22546817 PMID:23566959 PMID:28552779 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member affects expression EXP nickel chloride affects the expression of BCAR3 mRNA CTD PMID:22546817 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
JBrowse link
G Bcl10 BCL10, immune signaling adaptor affects expression EXP nickel chloride affects the expression of BCL10 mRNA CTD PMID:22546817 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
decreases response to substance
increases expression
ISO
EXP
nickel chloride results in decreased expression of BCL2 mRNA
BCL2 protein results in decreased susceptibility to nickel chloride
nickel chloride results in decreased expression of BCL2 protein
nickel chloride results in increased expression of BCL2 protein
CTD PMID:17442357 PMID:20391133 PMID:21837363 PMID:23828460 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO nickel chloride results in increased expression of BCL2A1 mRNA CTD PMID:17312168 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases response to substance
affects expression
decreases expression
ISO
EXP
nickel chloride results in increased expression of BCL2L1 protein
BCL2L1 protein results in decreased susceptibility to nickel chloride
nickel chloride affects the expression of BCL2L1 mRNA
nickel chloride results in decreased expression of BCL2L1 protein
CTD PMID:20391133 PMID:21837363 PMID:22546817 PMID:23828460 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l10 Bcl2-like 10 affects expression EXP nickel chloride affects the expression of BCL2L10 mRNA CTD PMID:22546817 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Bcl2l11 Bcl2-like 11 affects expression EXP nickel chloride affects the expression of BCL2L11 mRNA CTD PMID:22110744 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl2l13 Bcl2-like 13 affects expression EXP nickel chloride affects the expression of BCL2L13 mRNA CTD PMID:22546817 NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:154,056,127...154,108,985
JBrowse link
G Bcl2l2 Bcl2-like 2 affects expression EXP nickel chloride affects the expression of BCL2L2 mRNA CTD PMID:22546817 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bcl3 BCL3, transcription coactivator affects expression EXP nickel chloride affects the expression of BCL3 mRNA CTD PMID:22546817 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bcl6 BCL6, transcription repressor affects expression EXP nickel chloride affects the expression of BCL6 mRNA CTD PMID:22546817 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bcs1l BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone affects expression EXP nickel chloride affects the expression of BCS1L mRNA CTD PMID:22110744 NCBI chr 9:76,164,925...76,168,940
Ensembl chr 9:76,164,932...76,168,938
JBrowse link
G Bex3 brain expressed X-linked 3 affects expression EXP nickel chloride affects the expression of BEX3 mRNA CTD PMID:22546817 NCBI chr  X:99,273,238...99,274,799
Ensembl chr  X:99,273,161...99,274,800
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 affects expression EXP nickel chloride affects the expression of BHLHE41 mRNA CTD PMID:22110744 NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468
JBrowse link
G Bid BH3 interacting domain death agonist increases expression
affects expression
EXP nickel chloride results in increased expression of BID mRNA
nickel chloride affects the expression of BID mRNA
CTD PMID:21843586 PMID:22546817 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bik BCL2-interacting killer affects expression EXP nickel chloride affects the expression of BIK mRNA CTD PMID:22546817 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of BIRC3 mRNA
nickel chloride affects the expression of BIRC3 mRNA
CTD PMID:17312168 PMID:22546817 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects expression EXP nickel chloride affects the expression of BIRC5 mRNA CTD PMID:22546817 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bles03 basophilic leukemia expressed protein BLES03 decreases expression ISO nickel chloride results in decreased expression of BLES03 mRNA CTD PMID:17312168 NCBI chr 1:202,734,555...202,736,809
Ensembl chr 1:202,734,555...202,736,804
JBrowse link
G Bmf Bcl2 modifying factor affects expression EXP nickel chloride affects the expression of BMF mRNA CTD PMID:22546817 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression
multiple interactions
affects expression
ISO
EXP
nickel chloride results in increased expression of BNIP3 mRNA
HIF1A protein promotes the reaction [nickel chloride results in increased expression of BNIP3 protein]
nickel chloride affects the expression of BNIP3 mRNA
HIF1A affects the reaction [nickel chloride results in increased expression of BNIP3 mRNA]
CTD PMID:12426141 PMID:12729255 PMID:12839937 PMID:17312168 PMID:22110744 More... NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of BNIP3L mRNA
nickel chloride affects the expression of BNIP3L mRNA
CTD PMID:21455298 PMID:22110744 PMID:22546817 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Bok BCL2 family apoptosis regulator BOK affects expression EXP nickel chloride affects the expression of BOK mRNA CTD PMID:22546817 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO nickel chloride results in decreased expression of BRCA1 mRNA; nickel chloride results in decreased expression of BRCA1 protein CTD PMID:28472268 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brinp2 BMP/retinoic acid inducible neural specific 2 affects expression EXP nickel chloride affects the expression of BRINP2 mRNA CTD PMID:22546817 NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810
JBrowse link
G Btd biotinidase affects expression EXP nickel chloride affects the expression of BTD mRNA CTD PMID:22110744 NCBI chr16:6,863,068...6,894,345
Ensembl chr16:6,862,407...6,940,945
JBrowse link
G Btg1 BTG anti-proliferation factor 1 increases expression ISO nickel chloride results in increased expression of BTG1 mRNA CTD PMID:17312168 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions
increases expression
ISO TP53 protein affects the reaction [nickel chloride results in increased expression of BTG2 mRNA] CTD PMID:23566959 PMID:28552779 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Btg3 BTG anti-proliferation factor 3 affects expression EXP nickel chloride affects the expression of BTG3 mRNA CTD PMID:22546817 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 affects expression EXP nickel chloride affects the expression of BZW1 mRNA CTD PMID:22546817 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
JBrowse link
G C1s complement C1s affects expression EXP nickel chloride affects the expression of C1S mRNA CTD PMID:22110744 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G C2cd4d C2 calcium-dependent domain containing 4D affects expression EXP nickel chloride affects the expression of C2CD4D mRNA CTD PMID:22110744 NCBI chr 2:181,997,393...182,001,938
Ensembl chr 2:181,997,078...182,002,087
JBrowse link
G C3 complement C3 affects expression EXP nickel chloride affects the expression of C3 mRNA CTD PMID:22110744 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C7 complement C7 affects expression EXP nickel chloride affects the expression of C7 mRNA CTD PMID:22546817 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G C8b complement C8 beta chain affects expression EXP nickel chloride affects the expression of C8B mRNA CTD PMID:22110744 NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
JBrowse link
G C9 complement C9 affects expression EXP nickel chloride affects the expression of C9 mRNA CTD PMID:22546817 NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
JBrowse link
G Calm1 calmodulin 1 affects expression EXP nickel chloride affects the expression of CALM1 mRNA CTD PMID:22546817 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 affects expression EXP nickel chloride affects the expression of CALM2 mRNA CTD PMID:22546817 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta affects expression EXP nickel chloride affects the expression of CAMK2B mRNA CTD PMID:22546817 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta affects expression EXP nickel chloride affects the expression of CAMK2D mRNA CTD PMID:22546817 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma affects expression EXP nickel chloride affects the expression of CAMK2G mRNA CTD PMID:22546817 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
JBrowse link
G Car9 carbonic anhydrase 9 increases expression
multiple interactions
ISO nickel chloride results in increased expression of CA9 mRNA
HIF1A protein promotes the reaction [nickel chloride results in increased expression of CA9 protein]
CTD PMID:21455298 PMID:28552779 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Card10 caspase recruitment domain family, member 10 affects expression EXP nickel chloride affects the expression of CARD10 mRNA CTD PMID:22546817 NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224
JBrowse link
G Card9 caspase recruitment domain family, member 9 affects expression EXP nickel chloride affects the expression of CARD9 mRNA CTD PMID:22546817 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO nickel chloride results in increased expression of CARS1 mRNA CTD PMID:17312168 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein] which results in increased secretion of IL1B protein; [nickel chloride results in increased abundance of Nickel] which results in increased cleavage of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased cleavage of CASP1 protein]
CASP1 protein promotes the reaction [[Lipopolysaccharides co-treated with nickel chloride] results in increased secretion of IL1B protein]
CTD PMID:24158569 PMID:31943712 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp2 caspase 2 affects expression EXP nickel chloride affects the expression of CASP2 mRNA CTD PMID:22546817 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
increases cleavage
affects expression
multiple interactions
EXP
ISO
nickel chloride results in increased activity of CASP3 protein
nickel chloride results in increased expression of CASP3 mRNA; nickel chloride results in increased expression of CASP3 protein modified form
nickel chloride results in increased cleavage of CASP3 protein
nickel chloride affects the expression of CASP3 mRNA
[nickel chloride results in increased abundance of Nickel] which results in increased cleavage of CASP3 protein; [TP53 mutant form inhibits the reaction [nickel chloride results in increased activity of CASP9 protein]] which results in decreased cleavage of CASP3 protein; cobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of CASP3 protein]; nickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased cleavage of CASP3 protein]
pyrazolanthrone inhibits the reaction [nickel chloride results in increased activity of CASP3 protein]
CTD PMID:21828359 PMID:21843586 PMID:22172632 PMID:22546817 PMID:23566959 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 affects expression EXP nickel chloride affects the expression of CASP6 mRNA CTD PMID:22546817 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 multiple interactions
increases cleavage
affects expression
increases activity
EXP
ISO
pyrazolanthrone inhibits the reaction [nickel chloride results in increased activity of CASP7 protein]
nickel chloride results in increased cleavage of CASP7 protein
cobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of CASP7 protein]; nickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of CASP7 protein]
nickel chloride affects the expression of CASP7 mRNA
CTD PMID:21828359 PMID:21843586 PMID:22172632 PMID:22546817 PMID:28552779 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 affects expression EXP nickel chloride affects the expression of CASP8 mRNA CTD PMID:22546817 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity
decreases expression
affects expression
multiple interactions
EXP
ISO
nickel chloride results in increased activity of CASP9 protein
nickel chloride results in decreased expression of CASP9 protein
nickel chloride affects the expression of CASP9 mRNA
[TP53 mutant form inhibits the reaction [nickel chloride results in increased activity of CASP9 protein]] which results in decreased cleavage of CASP3 protein; pifithrin inhibits the reaction [nickel chloride results in increased activity of CASP9 protein]; TP53 mutant form inhibits the reaction [nickel chloride results in increased activity of CASP9 protein]
pyrazolanthrone inhibits the reaction [nickel chloride results in increased activity of CASP9 protein]
CTD PMID:21843586 PMID:22546817 PMID:23566959 PMID:28552779 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases response to substance
multiple interactions
decreases activity
decreases expression
ISO
EXP
CAT protein results in decreased susceptibility to nickel chloride
chromous chloride affects the reaction [nickel chloride results in decreased activity of CAT protein]; nickel chloride affects the reaction [chromous chloride results in decreased activity of CAT protein]
[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in decreased activity of CAT protein; [nickel chloride results in increased abundance of Nickel] which results in decreased activity of CAT protein; Fatty Acids, Omega-3 inhibits the reaction [[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in decreased activity of CAT protein]; Hydroxyapatites analog inhibits the reaction [nickel chloride results in decreased activity of CAT protein]
nickel chloride results in decreased expression of CAT protein
CTD PMID:22648416 PMID:23828460 PMID:25220231 PMID:30389395 PMID:31639282 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbs cystathionine beta synthase affects expression EXP nickel chloride affects the expression of CBS mRNA CTD PMID:22110744 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cbx6 chromobox 6 decreases expression ISO nickel chloride results in decreased expression of CBX6 mRNA CTD PMID:17312168 NCBI chr 7:111,372,979...111,383,109
Ensembl chr 7:111,372,980...111,383,091
JBrowse link
G Ccdc181 coiled-coil domain containing 181 affects expression EXP nickel chloride affects the expression of CCDC181 mRNA CTD PMID:22110744 NCBI chr13:76,624,567...76,638,224
Ensembl chr13:76,624,567...76,638,224
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 increases secretion
multiple interactions
ISO nickel chloride results in increased secretion of CCL1 protein
nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL1 mRNA]
CTD PMID:18437699 PMID:23090859 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
JBrowse link
G Ccl12 C-C motif chemokine ligand 12 affects expression ISO nickel chloride affects the expression of CCL12 mRNA CTD PMID:24670797 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
increases secretion
decreases expression
decreases secretion
ISO nickel chloride results in increased expression of CCL2 mRNA
nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 mRNA]
nickel chloride results in increased secretion of CCL2 protein
nickel chloride results in decreased expression of CCL2 mRNA
nickel chloride results in decreased secretion of CCL2 protein
CTD PMID:12839937 PMID:17312168 PMID:18437699 PMID:23090859 PMID:25458486 More... NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO nickel chloride results in increased expression of CCL20 mRNA CTD PMID:17312168 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases secretion
affects expression
ISO nickel chloride results in increased secretion of CCL22 protein
nickel chloride affects the expression of CCL22 mRNA
CTD PMID:18437699 PMID:24670797 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases secretion ISO nickel chloride results in increased secretion of CCL5 protein CTD PMID:18437699 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions
decreases secretion
ISO [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of CCL7 protein; nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL7 mRNA]
nickel chloride results in decreased secretion of CCL7 protein
CTD PMID:18437699 PMID:23090859 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccn5 cellular communication network factor 5 increases expression ISO nickel chloride results in increased expression of CCN5 mRNA CTD PMID:21455298 NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636
JBrowse link
G Ccnb1 cyclin B1 affects expression EXP nickel chloride affects the expression of CCNB1 mRNA CTD PMID:22546817 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO nickel chloride results in increased expression of CCNB2 mRNA CTD PMID:17547211 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnc cyclin C affects expression EXP nickel chloride affects the expression of CCNC mRNA CTD PMID:22546817 NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
affects expression
decreases phosphorylation
decreases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel chloride results in decreased phosphorylation of CCND1 protein]; nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein
nickel chloride affects the expression of CCND1 mRNA
CHUK protein affects the reaction [nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein]; nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein
nickel chloride results in decreased expression of CCND1 mRNA
CTD PMID:17312168 PMID:18792914 PMID:22546817 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO nickel chloride results in decreased expression of CCND2 mRNA CTD PMID:17312168 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccne1 cyclin E1 affects expression EXP nickel chloride affects the expression of CCNE1 mRNA CTD PMID:22546817 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 decreases expression ISO nickel chloride results in decreased expression of CCNE2 mRNA CTD PMID:17312168 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccnf cyclin F affects expression EXP nickel chloride affects the expression of CCNF mRNA CTD PMID:22546817 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
JBrowse link
G Ccng1 cyclin G1 affects expression EXP nickel chloride affects the expression of CCNG1 mRNA CTD PMID:22546817 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccng2 cyclin G2 multiple interactions
affects expression
increases expression
ISO
EXP
HIF1A affects the reaction [nickel chloride results in increased expression of CCNG2 mRNA]
nickel chloride affects the expression of CCNG2 mRNA
CTD PMID:12729255 PMID:17312168 PMID:21455298 PMID:22546817 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Ccnh cyclin H affects expression EXP nickel chloride affects the expression of CCNH mRNA CTD PMID:22546817 NCBI chr 2:15,834,833...15,855,643
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Ccnj cyclin J affects expression EXP nickel chloride affects the expression of CCNJ mRNA CTD PMID:22110744 PMID:22546817 NCBI chr 1:239,659,588...239,677,367 JBrowse link
G Ccr7 C-C motif chemokine receptor 7 increases expression ISO nickel chloride results in increased expression of CCR7 protein CTD PMID:15737199 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 affects expression EXP nickel chloride affects the expression of CCT2 mRNA CTD PMID:22546817 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 affects expression EXP nickel chloride affects the expression of CCT7 mRNA CTD PMID:22546817 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580
JBrowse link
G Cd109 CD109 molecule increases expression ISO nickel chloride results in increased expression of CD109 protein CTD PMID:33774146 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex affects expression EXP nickel chloride affects the expression of CD3G mRNA CTD PMID:22546817 NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147
JBrowse link
G Cd40lg CD40 ligand affects expression ISO nickel chloride affects the expression of CD40LG mRNA CTD PMID:24670797 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO nickel chloride results in increased expression of CD44 protein CTD PMID:26962057 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd80 Cd80 molecule increases expression ISO nickel chloride results in increased expression of CD80 protein CTD PMID:25458486 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule increases expression
increases secretion
ISO nickel chloride results in increased expression of CD86 mRNA; nickel chloride results in increased expression of CD86 protein
nickel chloride results in increased secretion of CD86 protein
CTD PMID:15737199 PMID:19665512 PMID:19844976 PMID:33774146 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc20 cell division cycle 20 affects expression EXP nickel chloride affects the expression of CDC20 mRNA CTD PMID:22546817 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc23 cell division cycle 23 decreases expression ISO nickel chloride results in decreased expression of CDC23 mRNA CTD PMID:17312168 NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163
JBrowse link
G Cdc25a cell division cycle 25A affects expression EXP nickel chloride affects the expression of CDC25A mRNA CTD PMID:22546817 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc25b cell division cycle 25B affects expression EXP nickel chloride affects the expression of CDC25B mRNA CTD PMID:22546817 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdc25c cell division cycle 25C affects expression EXP nickel chloride affects the expression of CDC25C mRNA CTD PMID:22546817 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc27 cell division cycle 27 affects expression EXP nickel chloride affects the expression of CDC27 mRNA CTD PMID:22546817 NCBI chr10:89,400,931...89,449,823
Ensembl chr10:89,400,940...89,449,736
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone affects expression EXP nickel chloride affects the expression of CDC37 mRNA CTD PMID:22546817 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Cdc37l1 cell division cycle 37-like 1 affects expression EXP nickel chloride affects the expression of CDC37L1 mRNA CTD PMID:22546817 NCBI chr 1:226,705,019...226,733,994
Ensembl chr 1:226,705,003...226,761,175
JBrowse link
G Cdc7 cell division cycle 7 affects expression EXP nickel chloride affects the expression of CDC7 mRNA CTD PMID:22546817 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
JBrowse link
G Cdca2 cell division cycle associated 2 affects expression EXP nickel chloride affects the expression of CDCA2 mRNA CTD PMID:22546817 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
JBrowse link
G Cdca5 cell division cycle associated 5 affects expression EXP nickel chloride affects the expression of CDCA5 mRNA CTD PMID:22546817 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases methylation
decreases expression
ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [nickel chloride results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased methylation of CDH1 promoter]; Allopurinol inhibits the reaction [nickel chloride results in decreased expression of CDH1 protein]; decitabine inhibits the reaction [nickel chloride results in decreased expression of CDH1 mRNA]; HIF1A mutant form inhibits the reaction [nickel chloride results in decreased expression of CDH1 protein]; nickel chloride promotes the reaction [HIF1A protein binds to CDH1 promoter]; nickel chloride promotes the reaction [SNAI1 protein binds to CDH1 promoter]; nickel chloride promotes the reaction [SNAI2 protein binds to CDH1 promoter]
nickel chloride results in decreased expression of CDH1 mRNA; nickel chloride results in decreased expression of CDH1 protein
CTD PMID:22648416 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh17 cadherin 17 affects expression EXP nickel chloride affects the expression of CDH17 mRNA CTD PMID:22110744 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884
JBrowse link
G Cdk11b cyclin-dependent kinase 11B affects expression EXP nickel chloride affects the expression of CDC2L1 mRNA CTD PMID:22546817 NCBI chr 5:166,212,761...166,238,883
Ensembl chr 5:166,212,829...166,238,876
JBrowse link
G Cdk13 cyclin-dependent kinase 13 affects expression EXP nickel chloride affects the expression of CDK13 mRNA CTD PMID:22546817 NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721
JBrowse link
G Cdk20 cyclin-dependent kinase 20 affects expression EXP nickel chloride affects the expression of CDK20 mRNA CTD PMID:22546817 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826
JBrowse link
G Cdk2ap1 cyclin-dependent kinase 2 associated protein 1 affects expression EXP nickel chloride affects the expression of CDK2AP1 mRNA CTD PMID:22546817 NCBI chr12:32,249,783...32,258,483
Ensembl chr12:32,249,747...32,258,479
JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression EXP nickel chloride affects the expression of CDK4 mRNA CTD PMID:22546817 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5 cyclin-dependent kinase 5 affects expression EXP nickel chloride affects the expression of CDK5 mRNA CTD PMID:22546817 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk6 cyclin-dependent kinase 6 affects expression EXP nickel chloride affects the expression of CDK6 mRNA CTD PMID:22546817 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdk9 cyclin-dependent kinase 9 affects expression EXP nickel chloride affects the expression of CDK9 mRNA CTD PMID:22546817 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
affects expression
multiple interactions
ISO
EXP
nickel chloride results in increased expression of CDKN1A mRNA
nickel chloride affects the expression of CDKN1A mRNA
nickel chloride results in increased expression of CDKN1A mRNA; nickel chloride results in increased expression of CDKN1A protein
HIF1A protein promotes the reaction [nickel chloride results in increased expression of CDKN1A protein]; nickel chloride promotes the reaction [TP63 mutant form results in increased expression of CDKN1A mRNA]; TP53 protein affects the reaction [nickel chloride results in increased expression of CDKN1A mRNA]; TP63 protein mutant form inhibits the reaction [nickel chloride results in increased expression of CDKN1A mRNA]; TP63 protein mutant form inhibits the reaction [nickel chloride results in increased expression of CDKN1A protein]
CTD PMID:12426141 PMID:12839937 PMID:17547211 PMID:21466819 PMID:22546817 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B affects expression
multiple interactions
increases expression
EXP
ISO
nickel chloride affects the expression of CDKN1B mRNA
HIF1A protein promotes the reaction [nickel chloride results in increased expression of CDKN1B protein]
CTD PMID:22546817 PMID:28552779 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A affects expression EXP nickel chloride affects the expression of CDKN2A mRNA CTD PMID:22546817 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B affects expression EXP nickel chloride affects the expression of CDKN2B mRNA CTD PMID:22546817 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects expression EXP nickel chloride affects the expression of CDKN2C mRNA CTD PMID:22546817 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 affects expression EXP nickel chloride affects the expression of CDKN3 mRNA CTD PMID:22546817 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 affects expression EXP nickel chloride affects the expression of CDT1 mRNA CTD PMID:22546817 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of CEBPB mRNA
nickel chloride affects the expression of CEBPB mRNA
CTD PMID:17312168 PMID:22546817 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO nickel chloride results in increased expression of CEBPD mRNA CTD PMID:17312168 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO nickel chloride results in increased expression of CEBPG mRNA CTD PMID:17312168 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Cenpf centromere protein F affects expression EXP nickel chloride affects the expression of CENPF mRNA CTD PMID:22546817 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression EXP nickel chloride affects the expression of CFLAR mRNA CTD PMID:22546817 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chd6 chromodomain helicase DNA binding protein 6 affects expression EXP nickel chloride affects the expression of CHD6 mRNA CTD PMID:22110744 NCBI chr 3:149,596,509...149,757,765
Ensembl chr 3:149,596,509...149,757,755
JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 affects expression EXP nickel chloride affects the expression of CHD7 mRNA CTD PMID:22110744 NCBI chr 5:21,812,007...21,995,358
Ensembl chr 5:21,812,070...21,995,358
JBrowse link
G Chi3l1 chitinase 3 like 1 affects expression ISO nickel chloride affects the expression of CHI3L1 mRNA CTD PMID:24670797 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit decreases expression EXP nickel chloride results in decreased expression of CHRND mRNA CTD PMID:24619124 NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 affects expression EXP nickel chloride affects the expression of CHSY1 mRNA CTD PMID:22110744 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
affects response to substance
ISO CHUK protein affects the reaction [nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein]
CHUK protein affects the susceptibility to nickel chloride
CTD PMID:18792914 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cidea cell death-inducing DFFA-like effector a affects expression EXP nickel chloride affects the expression of CIDEA mRNA CTD PMID:22546817 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cideb cell death-inducing DFFA-like effector b affects expression EXP nickel chloride affects the expression of CIDEB mRNA CTD PMID:22546817 NCBI chr15:29,252,203...29,256,759
Ensembl chr15:29,252,213...29,256,605
JBrowse link
G Cit citron rho-interacting serine/threonine kinase affects expression EXP nickel chloride affects the expression of CIT mRNA CTD PMID:22546817 NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression ISO nickel chloride results in increased expression of CITED2 mRNA CTD PMID:21455298 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 affects expression EXP nickel chloride affects the expression of CIZ1 mRNA CTD PMID:22546817 NCBI chr 3:15,658,479...15,675,716
Ensembl chr 3:15,658,539...15,673,762
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO nickel chloride results in increased expression of CKS2 mRNA CTD PMID:17547211 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 affects expression EXP nickel chloride affects the expression of CLCF1 mRNA CTD PMID:22110744 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605
JBrowse link
G Clcn4 chloride voltage-gated channel 4 affects expression EXP nickel chloride affects the expression of CLCN4 mRNA CTD PMID:22110744 NCBI chr  X:23,729,194...23,795,391
Ensembl chr  X:23,729,338...23,793,238
JBrowse link
G Clec5a C-type lectin domain containing 5A increases expression
affects expression
ISO nickel chloride results in increased expression of CLEC5A protein
nickel chloride affects the expression of CLEC5A mRNA
CTD PMID:33774146 NCBI chr 4:69,407,125...69,416,872
Ensembl chr 4:69,407,835...69,416,859
JBrowse link
G Clk1 CDC-like kinase 1 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of CLK1 mRNA
nickel chloride affects the expression of CLK1 mRNA
CTD PMID:17312168 PMID:22546817 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin affects expression EXP nickel chloride affects the expression of CLN3 mRNA CTD PMID:22110744 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking decreases expression ISO nickel chloride results in decreased expression of CLPTM1 mRNA CTD PMID:17547211 NCBI chr 1:79,289,478...79,321,079
Ensembl chr 1:79,289,477...79,321,092
JBrowse link
G Clrn3 clarin 3 affects expression EXP nickel chloride affects the expression of CLRN3 mRNA CTD PMID:22110744 NCBI chr 1:190,319,025...190,334,648
Ensembl chr 1:190,319,026...190,334,648
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain affects expression EXP nickel chloride affects the expression of COL18A1 mRNA CTD PMID:22546817 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Col3a1 collagen type III alpha 1 chain affects expression EXP nickel chloride affects the expression of COL3A1 mRNA CTD PMID:22110744 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Commd5 COMM domain containing 5 affects expression EXP nickel chloride affects the expression of COMMD5 mRNA CTD PMID:22546817 NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764
JBrowse link
G Cp ceruloplasmin increases expression ISO nickel chloride results in increased expression of CP mRNA CTD PMID:21455298 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A affects expression EXP nickel chloride affects the expression of CPT1A mRNA CTD PMID:22110744 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 affects expression EXP nickel chloride affects the expression of CREB3L1 mRNA CTD PMID:22110744 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
JBrowse link
G Crebrf CREB3 regulatory factor increases expression ISO nickel chloride results in increased expression of CREBRF mRNA CTD PMID:21455298 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999
JBrowse link
G Crk CRK proto-oncogene, adaptor protein affects expression EXP nickel chloride affects the expression of CRK mRNA CTD PMID:22546817 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Crlf2 cytokine receptor-like factor 2 increases expression
multiple interactions
affects expression
ISO nickel chloride results in increased expression of CRLF2 mRNA
[nickel chloride co-treated with Freund's Adjuvant] results in increased expression of CRLF2 protein
nickel chloride affects the expression of CRLF2 mRNA
CTD PMID:24670797 PMID:26044615 NCBI chr14:103,943...108,643
Ensembl chr14:103,939...108,642
JBrowse link
G Crp C-reactive protein multiple interactions ISO [nickel chloride results in increased abundance of Nickel] which results in increased expression of CRP mRNA; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of CRP mRNA] CTD PMID:31943712 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cryab crystallin, alpha B affects expression EXP nickel chloride affects the expression of CRYAB mRNA CTD PMID:22110744 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cse1l chromosome segregation 1 like affects expression EXP nickel chloride affects the expression of CSE1L mRNA CTD PMID:22546817 NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865
JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO nickel chloride results in increased expression of CSF1 mRNA CTD PMID:17312168 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf2 colony stimulating factor 2 increases expression
affects expression
ISO nickel chloride results in increased expression of CSF2 mRNA; nickel chloride results in increased expression of CSF2 protein
nickel chloride affects the expression of CSF2 mRNA
CTD PMID:17312168 PMID:21569788 PMID:24670797 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 increases expression
multiple interactions
ISO nickel chloride results in increased expression of CSF3 mRNA
[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of CSF3 protein; nickel chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CSF3 mRNA]
CTD PMID:17312168 PMID:18437699 PMID:23090859 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Csnk1d casein kinase 1, delta decreases expression
affects expression
ISO
EXP
nickel chloride results in decreased expression of CSNK1D mRNA
nickel chloride affects the expression of CSNK1D mRNA
CTD PMID:17312168 PMID:22546817 NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 affects expression EXP nickel chloride affects the expression of CSNK2A2 mRNA CTD PMID:22546817 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 affects expression EXP nickel chloride affects the expression of CSRNP1 mRNA CTD PMID:22546817 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
JBrowse link
G Csta cystatin A affects expression ISO nickel chloride affects the expression of CSTA mRNA CTD PMID:27825931 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
JBrowse link
G Cstb cystatin B affects expression EXP nickel chloride affects the expression of CSTB mRNA CTD PMID:22546817 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G Ctcf CCCTC-binding factor affects expression EXP nickel chloride affects the expression of CTCF mRNA CTD PMID:22546817 NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
JBrowse link
G Cth cystathionine gamma-lyase increases expression
multiple interactions
decreases expression
ISO nickel chloride results in increased expression of CTH mRNA
CTH gene mutant form promotes the reaction [nickel chloride results in increased expression of ACTA2 protein]
nickel chloride results in decreased expression of CTH mRNA; nickel chloride results in decreased expression of CTH protein
nickel chloride inhibits the reaction [SP1 protein binds to CTH promoter]; nickel chloride inhibits the reaction [SP1 protein results in increased expression of CTH protein]; sodium bisulfide inhibits the reaction [nickel chloride inhibits the reaction [SP1 protein binds to CTH promoter]]
CTD PMID:17312168 PMID:30055191 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctsc cathepsin C affects expression EXP nickel chloride affects the expression of CTSC mRNA CTD PMID:22110744 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Cul1 cullin 1 affects expression EXP nickel chloride affects the expression of CUL1 mRNA CTD PMID:22546817 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
JBrowse link
G Cul2 cullin 2 affects expression EXP nickel chloride affects the expression of CUL2 mRNA CTD PMID:22546817 NCBI chr17:54,169,086...54,210,197
Ensembl chr17:54,169,086...54,209,968
JBrowse link
G Cwf19l1 CWF19 like cell cycle control factor 1 affects expression EXP nickel chloride affects the expression of CWF19L1 mRNA CTD PMID:22546817 NCBI chr 1:242,997,720...243,020,989
Ensembl chr 1:242,997,726...243,020,961
JBrowse link
G Cwf19l2 CWF19 like cell cycle control factor 2 affects expression EXP nickel chloride affects the expression of CWF19L2 mRNA CTD PMID:22546817 NCBI chr 6:290,148...356,636
Ensembl chr 6:281,685...356,604
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO nickel chloride results in increased expression of CX3CL1 mRNA CTD PMID:17312168 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule decreases expression ISO nickel chloride results in decreased expression of CXADR mRNA CTD PMID:17312168 NCBI chr11:16,982,752...17,030,078
Ensembl chr11:16,982,860...17,030,046
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO nickel chloride results in increased expression of CXCL1 mRNA CTD PMID:17312168 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions
increases expression
ISO nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA]
nickel chloride results in increased expression of CXCL10 mRNA
CTD PMID:23090859 PMID:27427241 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 affects expression
multiple interactions
EXP
ISO
nickel chloride affects the expression of CXCL11 mRNA
nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL11 mRNA]
CTD PMID:22110744 PMID:23090859 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases secretion ISO nickel chloride results in decreased secretion of CXCL12 protein CTD PMID:18437699 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 multiple interactions ISO nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL13 mRNA] CTD PMID:23090859 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO nickel chloride results in decreased expression of CXCL14 protein CTD PMID:31734321 NCBI chr17:8,317,933...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cxcl16 C-X-C motif chemokine ligand 16 increases expression ISO nickel chloride results in increased expression of CXCL16 mRNA CTD PMID:26044615 NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
decreases expression
multiple interactions
ISO nickel chloride results in increased expression of CXCL2 mRNA
nickel chloride results in decreased expression of CXCL2 protein
nickel chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL2 mRNA]
CTD PMID:17312168 PMID:23090859 PMID:23178550 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO nickel chloride results in increased expression of CXCL1 mRNA CTD PMID:17312168 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO nickel chloride results in increased expression of CXCL6 mRNA CTD PMID:17312168 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 affects expression
multiple interactions
EXP
ISO
nickel chloride affects the expression of CXCL9 mRNA
nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL9 mRNA]
CTD PMID:22110744 PMID:23090859 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression ISO nickel chloride results in increased expression of CXCR1 protein CTD PMID:33774146 NCBI chr 9:75,768,124...75,771,122
Ensembl chr 9:75,766,770...75,771,084
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 increases expression ISO nickel chloride results in increased expression of CXCR3 protein CTD PMID:33774146 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
multiple interactions
ISO nickel chloride results in decreased expression of CYP1A1 protein
nickel chloride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
CTD PMID:14645679 PMID:21784029 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression ISO nickel chloride results in decreased expression of CYP1A2 protein CTD PMID:21784029 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO nickel chloride results in decreased expression of CYP1B1 mRNA CTD PMID:12839937 PMID:14645679 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 affects expression EXP nickel chloride affects the expression of CYP27A1 mRNA CTD PMID:22110744 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Dab2 DAB adaptor protein 2 decreases expression ISO nickel chloride results in decreased expression of DAB2 mRNA CTD PMID:17312168 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Dach1 dachshund family transcription factor 1 decreases expression ISO nickel chloride results in decreased expression of DACH1 mRNA CTD PMID:17312168 NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922
JBrowse link
G Dad1 defender against cell death 1 affects expression EXP nickel chloride affects the expression of DAD1 mRNA CTD PMID:22546817 NCBI chr15:27,677,285...27,697,275
Ensembl chr15:27,677,268...27,697,347
JBrowse link
G Dap death-associated protein affects expression EXP nickel chloride affects the expression of DAP mRNA CTD PMID:22546817 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752
JBrowse link
G Dap3 death associated protein 3 affects expression EXP nickel chloride affects the expression of DAP3 mRNA CTD PMID:22546817 NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461
JBrowse link
G Dapl1 death associated protein-like 1 affects expression EXP nickel chloride affects the expression of DAPL1 mRNA CTD PMID:22110744 NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940
JBrowse link
G Daxx death-domain associated protein affects expression EXP nickel chloride affects the expression of DAXX mRNA CTD PMID:22546817 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Dbi diazepam binding inhibitor affects expression EXP nickel chloride affects the expression of DBI mRNA CTD PMID:22110744 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase affects expression EXP nickel chloride affects the expression of DCXR mRNA CTD PMID:22110744 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of DDIT3 mRNA
nickel chloride affects the expression of DDIT3 mRNA
CTD PMID:12426141 PMID:12839937 PMID:22546817 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of DDIT4 mRNA
nickel chloride affects the expression of DDIT4 mRNA
CTD PMID:17312168 PMID:22110744 PMID:22546817 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddx17 DEAD-box helicase 17 decreases expression ISO nickel chloride results in decreased expression of DDX17 mRNA CTD PMID:17312168 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 decreases expression ISO nickel chloride results in decreased expression of DEGS1 mRNA CTD PMID:17312168 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664
JBrowse link
G Depdc7 DEP domain containing 7 affects expression EXP nickel chloride affects the expression of DEPDC7 mRNA CTD PMID:22110744 NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein affects expression EXP nickel chloride affects the expression of DEPTOR mRNA CTD PMID:22110744 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression
decreases expression
EXP
ISO
nickel chloride affects the expression of DHCR24 mRNA
nickel chloride results in decreased expression of DHCR24 mRNA
CTD PMID:17312168 PMID:22110744 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) affects expression EXP nickel chloride affects the expression of DHODH mRNA CTD PMID:22110744 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
JBrowse link
G Dicer1 dicer 1 ribonuclease III decreases expression ISO nickel chloride results in decreased expression of DICER1 mRNA CTD PMID:17312168 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dipk2a divergent protein kinase domain 2A affects expression EXP nickel chloride affects the expression of DIPK2A mRNA CTD PMID:22110744 NCBI chr 8:95,070,695...95,089,815
Ensembl chr 8:95,030,279...95,089,815
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO nickel chloride results in increased expression of DKK1 mRNA CTD PMID:17547211 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 affects expression EXP nickel chloride affects the expression of DLG5 mRNA CTD PMID:22546817 NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837
JBrowse link
G Dlgap5 DLG associated protein 5 affects expression EXP nickel chloride affects the expression of DLGAP5 mRNA CTD PMID:22546817 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dnajb13 DnaJ heat shock protein family (Hsp40) member B13 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of DNAJB13 mRNA
nickel chloride affects the expression of DNAJB13 mRNA
CTD PMID:21455298 PMID:22546817 NCBI chr 1:154,848,586...154,863,042
Ensembl chr 1:154,848,594...154,862,963
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 decreases expression ISO nickel chloride results in decreased expression of DNAJB4 mRNA CTD PMID:17312168 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 increases expression ISO nickel chloride results in increased expression of DNAJB6 mRNA CTD PMID:17312168 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO nickel chloride results in increased expression of DNAJB9 mRNA CTD PMID:17312168 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnase1 deoxyribonuclease 1 affects expression EXP nickel chloride affects the expression of DNASE1 mRNA CTD PMID:22546817 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 affects expression EXP nickel chloride affects the expression of DNASE1L3 mRNA CTD PMID:22546817 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317
JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal affects expression EXP nickel chloride affects the expression of DNASE2 mRNA CTD PMID:22546817 NCBI chr19:23,244,661...23,247,329
Ensembl chr19:23,244,664...23,247,376
JBrowse link
G Dnm2 dynamin 2 affects expression EXP nickel chloride affects the expression of DNM2 mRNA CTD PMID:22546817 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
JBrowse link
G Dpp7 dipeptidylpeptidase 7 affects expression EXP nickel chloride affects the expression of DPP7 mRNA CTD PMID:22110744 NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355
JBrowse link
G Dst dystonin affects expression EXP nickel chloride affects the expression of DST mRNA CTD PMID:22546817 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
JBrowse link
G Dstyk dual serine/threonine and tyrosine protein kinase affects expression EXP nickel chloride affects the expression of DSTYK mRNA CTD PMID:22546817 NCBI chr13:43,857,266...43,905,280
Ensembl chr13:43,857,266...43,905,269
JBrowse link
G Dtymk deoxythymidylate kinase affects expression EXP nickel chloride affects the expression of DTYMK mRNA CTD PMID:22546817 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of DUSP1 mRNA
nickel chloride affects the expression of DUSP1 mRNA
CTD PMID:17547211 PMID:22110744 PMID:22546817 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO nickel chloride results in increased expression of DUSP6 mRNA CTD PMID:17312168 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dzip1 DAZ interacting zinc finger protein 1 decreases expression ISO nickel chloride results in decreased expression of DZIP1 mRNA CTD PMID:17312168 NCBI chr15:95,956,329...96,009,994
Ensembl chr15:95,956,398...96,010,066
JBrowse link
G E2f1 E2F transcription factor 1 increases expression
affects expression
multiple interactions
ISO
EXP
nickel chloride results in increased expression of E2F1 mRNA
nickel chloride affects the expression of E2F1 mRNA
HIF1A affects the reaction [nickel chloride results in increased expression of E2F1 mRNA]
CTD PMID:12729255 PMID:22546817 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Eaf2 ELL associated factor 2 affects expression EXP nickel chloride affects the expression of EAF2 mRNA CTD PMID:22546817 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610
JBrowse link
G Ebi3 Epstein-Barr virus induced 3 increases expression ISO nickel chloride results in increased expression of EBI3 mRNA CTD PMID:30421605 NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544
JBrowse link
G Edaradd EDAR-associated death domain multiple interactions ISO nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of EDARADD mRNA] CTD PMID:23090859 NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447
JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 decreases expression ISO nickel chloride results in decreased expression of EDEM3 mRNA CTD PMID:17312168 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
JBrowse link
G Edn2 endothelin 2 increases expression ISO nickel chloride results in increased expression of EDN2 mRNA CTD PMID:21455298 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 increases expression ISO nickel chloride results in increased expression of EEF2 mRNA CTD PMID:12729255 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 increases expression ISO nickel chloride results in increased expression of EFEMP2 mRNA CTD PMID:21455298 NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414
JBrowse link
G Efna1 ephrin A1 increases expression ISO nickel chloride results in increased expression of EFNA1 mRNA CTD PMID:17312168 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of EGF protein CTD PMID:18437699 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor affects expression
multiple interactions
increases expression
EXP
ISO
nickel chloride affects the expression of EGFR mRNA
RECK protein inhibits the reaction [nickel chloride results in increased expression of EGFR protein]
CTD PMID:22546817 PMID:26026961 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 decreases activity
increases expression
affects expression
multiple interactions
ISO
EXP
nickel chloride results in decreased activity of EGLN1 protein
nickel chloride results in increased expression of EGLN1 mRNA
nickel chloride affects the expression of EGLN1 mRNA
HIF1A affects the reaction [nickel chloride results in increased expression of EGLN1 mRNA]
CTD PMID:12729255 PMID:12839937 PMID:16649251 PMID:17312168 PMID:22110744 NCBI chr19:52,867,914...52,907,169
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of EGLN3 mRNA
nickel chloride affects the expression of EGLN3 mRNA
CTD PMID:21455298 PMID:22110744 PMID:22546817 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Egr1 early growth response 1 increases expression EXP nickel chloride results in increased expression of EGR1 mRNA CTD PMID:24619124 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eid1 EP300 interacting inhibitor of differentiation 1 decreases expression ISO nickel chloride results in decreased expression of EID1 mRNA CTD PMID:17312168 NCBI chr 3:112,922,961...112,924,680
Ensembl chr 3:112,922,668...112,924,752
JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked decreases expression ISO nickel chloride results in decreased expression of EIF1AX mRNA CTD PMID:17312168 NCBI chr  X:35,498,698...35,513,402
Ensembl chr  X:35,498,517...35,513,335
JBrowse link
G Elk1 ETS transcription factor ELK1 affects expression EXP nickel chloride affects the expression of ELK1 mRNA CTD PMID:22546817 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 affects expression EXP nickel chloride affects the expression of ELOVL6 mRNA CTD PMID:22110744 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Emp1 epithelial membrane protein 1 affects expression EXP nickel chloride affects the expression of EMP1 mRNA CTD PMID:22110744 NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression EXP nickel chloride affects the expression of ENC1 mRNA CTD PMID:22110744 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Eno2 enolase 2 increases expression ISO nickel chloride results in increased expression of ENO2 mRNA CTD PMID:17312168 PMID:21455298 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 decreases expression ISO nickel chloride results in decreased expression of ENTPD4 mRNA CTD PMID:17312168 NCBI chr15:44,630,873...44,658,706
Ensembl chr15:44,630,873...44,658,706
JBrowse link
G Epor erythropoietin receptor affects expression ISO nickel chloride affects the expression of EPOR mRNA CTD PMID:26044615 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G Eral1 Era-like 12S mitochondrial rRNA chaperone 1 affects expression EXP nickel chloride affects the expression of ERAL1 mRNA CTD PMID:22546817 NCBI chr10:62,961,729...62,968,766
Ensembl chr10:62,961,730...62,968,994
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 affects expression EXP nickel chloride affects the expression of ERBB3 mRNA CTD PMID:22546817 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha affects expression
increases expression
multiple interactions
EXP
ISO
nickel chloride affects the expression of ERO1A mRNA
nickel chloride results in increased expression of ERO1A mRNA
HIF1A affects the reaction [nickel chloride results in increased expression of ERO1A mRNA]
CTD PMID:12729255 PMID:22110744 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 affects expression EXP nickel chloride affects the expression of ERRFI1 mRNA CTD PMID:22110744 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase affects expression EXP nickel chloride affects the expression of ESPL1 mRNA CTD PMID:22546817 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
JBrowse link
G Esr1 estrogen receptor 1 affects response to substance
decreases expression
multiple interactions
ISO ESR1 protein affects the susceptibility to nickel chloride
nickel chloride results in decreased expression of ESR1 mRNA; nickel chloride results in decreased expression of ESR1 protein
nickel chloride binds to and results in increased activity of ESR1 protein; nickel chloride inhibits the reaction [Estradiol binds to ESR1 protein]
CTD PMID:12746304 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression ISO nickel chloride results in increased expression of F2RL1 mRNA CTD PMID:17312168 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G F5 coagulation factor V decreases expression ISO nickel chloride results in decreased expression of F5 mRNA CTD PMID:17547211 NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Fabp1 fatty acid binding protein 1 affects expression EXP nickel chloride affects the expression of FABP1 mRNA CTD PMID:22110744 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Faim Fas apoptotic inhibitory molecule affects expression EXP nickel chloride affects the expression of FAIM mRNA CTD PMID:22546817 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562
JBrowse link
G Fam102b family with sequence similarity 102, member B affects expression EXP nickel chloride affects the expression of FAM102B mRNA CTD PMID:22110744 NCBI chr 2:196,608,499...196,663,371
Ensembl chr 2:196,608,499...196,663,371
JBrowse link
G FAM120C family with sequence similarity 120C affects expression EXP nickel chloride affects the expression of FAM120C mRNA CTD PMID:22110744 NCBI chr  X:20,324,046...20,477,831
Ensembl chr  X:20,323,381...20,477,275
JBrowse link
G Fam13a family with sequence similarity 13, member A increases expression ISO nickel chloride results in increased expression of FAM13A mRNA CTD PMID:21455298 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
JBrowse link
G Fancd2 FA complementation group D2 decreases expression ISO nickel chloride results in decreased expression of FANCD2 mRNA; nickel chloride results in decreased expression of FANCD2 protein CTD PMID:28472268 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
JBrowse link
G Fancl FA complementation group L decreases expression ISO nickel chloride results in decreased expression of FANCL mRNA CTD PMID:17312168 NCBI chr14:100,249,733...100,317,958
Ensembl chr14:100,248,875...100,314,255
JBrowse link
G Fas Fas cell surface death receptor affects expression EXP nickel chloride affects the expression of FAS mRNA CTD PMID:22546817 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fasn fatty acid synthase affects expression
decreases expression
EXP
ISO
nickel chloride affects the expression of FASN mRNA
nickel chloride results in decreased expression of FASN mRNA
CTD PMID:17312168 PMID:22110744 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbln5 fibulin 5 affects expression EXP nickel chloride affects the expression of FBLN5 mRNA CTD PMID:22110744 NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755
JBrowse link
G Fbxo2 F-box protein 2 affects expression EXP nickel chloride affects the expression of FBXO2 mRNA CTD PMID:22546817 NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355
JBrowse link
G Fbxo30 F-box protein 30 affects expression EXP nickel chloride affects the expression of FBXO30 mRNA CTD PMID:22110744 NCBI chr 1:5,655,341...5,671,558
Ensembl chr 1:5,655,339...5,672,441
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO nickel chloride results in increased expression of FBXO32 mRNA CTD PMID:21455298 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fbxw2 F-box and WD repeat domain containing 2 decreases expression ISO nickel chloride results in decreased expression of FBXW2 mRNA CTD PMID:17312168 PMID:17547211 NCBI chr 3:18,088,859...18,114,387
Ensembl chr 3:18,088,865...18,114,381
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO nickel chloride results in decreased expression of FDPS mRNA CTD PMID:17547211 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fem1b feminization of XX and XO animals 1B decreases expression
affects expression
ISO
EXP
nickel chloride results in decreased expression of FEM1B mRNA
nickel chloride affects the expression of FEM1B mRNA
CTD PMID:17312168 PMID:22546817 NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577
JBrowse link
G Fgf1 fibroblast growth factor 1 affects expression EXP nickel chloride affects the expression of FGF1 mRNA CTD PMID:22546817 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgf11 fibroblast growth factor 11 increases expression ISO nickel chloride results in increased expression of FGF11 mRNA CTD PMID:21455298 NCBI chr10:54,516,508...54,522,067
Ensembl chr10:54,517,077...54,522,062
JBrowse link
G Fgf2 fibroblast growth factor 2 affects expression EXP nickel chloride affects the expression of FGF2 mRNA CTD PMID:22546817 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgfbp3 fibroblast growth factor binding protein 3 affects expression EXP nickel chloride affects the expression of FGFBP3 mRNA CTD PMID:22110744 NCBI chr 1:234,644,023...234,646,028
Ensembl chr 1:234,644,019...234,646,547
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase affects expression EXP nickel chloride affects the expression of FGR mRNA CTD PMID:22546817 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression ISO nickel chloride results in decreased expression of FHIT protein CTD PMID:14971660 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Fis1 fission, mitochondrial 1 affects expression EXP nickel chloride affects the expression of FIS1 mRNA CTD PMID:22546817 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 affects expression EXP nickel chloride affects the expression of FKBP11 mRNA CTD PMID:22110744 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
JBrowse link
G Flot1 flotillin 1 affects expression EXP nickel chloride affects the expression of FLOT1 mRNA CTD PMID:22110744 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 increases expression ISO nickel chloride results in increased expression of FLRT2 mRNA CTD PMID:17312168 NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785
JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression
ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [nickel chloride results in increased expression of FN1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of FN1 protein]; Allopurinol inhibits the reaction [nickel chloride results in increased expression of FN1 protein]; HIF1A mutant form inhibits the reaction [nickel chloride results in increased expression of FN1 protein]; sodium bisulfide inhibits the reaction [nickel chloride results in increased expression of FN1 mRNA]
nickel chloride results in increased expression of FN1 mRNA; nickel chloride results in increased expression of FN1 protein
CTD PMID:22648416 PMID:30055191 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fn3k fructosamine 3 kinase increases expression EXP nickel chloride results in increased expression of FN3K mRNA CTD PMID:24619124 NCBI chr10:106,700,302...106,715,903
Ensembl chr10:106,700,670...106,715,895
JBrowse link
G Fnbp1 formin binding protein 1 increases expression ISO nickel chloride results in increased expression of FNBP1 mRNA CTD PMID:17312168 NCBI chr 3:14,316,011...14,386,704
Ensembl chr 3:14,309,640...14,424,881
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP nickel chloride results in increased expression of FOS mRNA CTD PMID:24619124 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [nickel chloride results in increased expression of GADD45A protein] which results in decreased expression of FOSB protein CTD PMID:23536762 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO nickel chloride results in increased expression of FOSL1 mRNA CTD PMID:17547211 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression ISO nickel chloride results in increased expression of FOSL2 mRNA CTD PMID:17312168 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Foxo3 forkhead box O3 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of FOXO3 mRNA
nickel chloride affects the expression of FOXO3 mRNA
CTD PMID:17312168 PMID:22546817 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Foxq1 forkhead box Q1 affects expression EXP nickel chloride affects the expression of FOXQ1 mRNA CTD PMID:22110744 NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
JBrowse link
G Fpgt fucose-1-phosphate guanylyltransferase decreases expression ISO nickel chloride results in decreased expression of FPGT mRNA CTD PMID:17312168 NCBI chr 2:244,099,031...244,119,967
Ensembl chr 2:244,099,076...244,119,899
JBrowse link
G Fstl3 follistatin like 3 affects expression EXP nickel chloride affects the expression of FSTL3 mRNA CTD PMID:22110744 NCBI chr 7:9,924,670...9,929,195
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions ISO [nickel chloride results in increased activity of ACO1 protein] inhibits the reaction [ferrous sulfate results in increased expression of FTL protein] CTD PMID:16039939 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) decreases expression ISO nickel chloride results in decreased expression of FURIN mRNA CTD PMID:17547211 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link
G Fut8 fucosyltransferase 8 increases expression ISO nickel chloride results in increased expression of FUT8 mRNA CTD PMID:17312168 NCBI chr 6:95,948,230...96,176,677
Ensembl chr 6:95,949,991...96,176,677
JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 affects expression EXP nickel chloride affects the expression of FZR1 mRNA CTD PMID:22546817 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 affects expression EXP nickel chloride affects the expression of G6PC1 mRNA CTD PMID:22110744 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of G6PDX mRNA
nickel chloride affects the expression of G6PD mRNA
CTD PMID:12426141 PMID:22546817 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
affects expression
multiple interactions
ISO
EXP
nickel chloride results in increased expression of GADD45A mRNA
nickel chloride affects the expression of GADD45A mRNA
[nickel chloride results in increased expression of GADD45A protein] which results in increased expression of PPP2CA protein; nickel chloride results in increased expression of GADD45A mRNA
[nickel chloride results in increased expression of GADD45A protein] which results in decreased expression of FOSB protein; [nickel chloride results in increased expression of GADD45A protein] which results in decreased phosphorylation of and results in decreased expression of JUN protein; [nickel chloride results in increased expression of GADD45A protein] which results in decreased phosphorylation of ATF2 protein; GADD45A protein inhibits the reaction [nickel chloride results in increased activity of MAP2K3 protein]; GADD45A protein inhibits the reaction [nickel chloride results in increased activity of MAP2K4 protein]; GADD45A protein inhibits the reaction [nickel chloride results in increased activity of MAP2K6 protein]; GADD45A protein inhibits the reaction [nickel chloride results in increased activity of MAP2K7 protein]; nickel chloride results in increased stability of and results in increased expression of GADD45A protein
CTD PMID:12839937 PMID:22546817 PMID:23536762 PMID:23566959 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta affects expression EXP nickel chloride affects the expression of GADD45B mRNA CTD PMID:22546817 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma affects expression EXP nickel chloride affects the expression of GADD45G mRNA CTD PMID:22546817 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gak cyclin G associated kinase affects expression EXP nickel chloride affects the expression of GAK mRNA CTD PMID:22546817 NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398
JBrowse link
G Galnt11 polypeptide N-acetylgalactosaminyltransferase 11 decreases expression ISO nickel chloride results in decreased expression of GALNT11 mRNA CTD PMID:17312168 NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140
JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 decreases expression EXP nickel chloride results in decreased expression of GALNT2 mRNA CTD PMID:24619124 NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression
affects expression
multiple interactions
ISO
EXP
nickel chloride results in increased expression of GAPDH mRNA
nickel chloride affects the expression of GAPDH mRNA
HIF1A affects the reaction [nickel chloride results in increased expression of GAPDH mRNA]; HIF1A protein affects the reaction [nickel chloride results in increased expression of GAPDH mRNA]
CTD PMID:10646848 PMID:12426141 PMID:12839937 PMID:22546817 PMID:23566959 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO nickel chloride results in decreased expression of GAS1 mRNA CTD PMID:12839937 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gas2 growth arrest-specific 2 affects expression EXP nickel chloride affects the expression of GAS2 mRNA CTD PMID:22110744 NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619
JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO nickel chloride results in increased expression of GATA6 mRNA CTD PMID:17312168 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression
increases expression
multiple interactions
EXP
ISO
nickel chloride affects the expression of GBE1 mRNA
nickel chloride results in increased expression of GBE1 mRNA
HIF1A protein affects the reaction [nickel chloride results in increased expression of GBE1 mRNA]
CTD PMID:15094311 PMID:22110744 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO nickel chloride results in increased expression of GBP1 mRNA CTD PMID:17312168 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
JBrowse link
G Gcat glycine C-acetyltransferase affects expression EXP nickel chloride affects the expression of GCAT mRNA CTD PMID:22110744 NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473
JBrowse link
G Gch1 GTP cyclohydrolase 1 affects expression EXP nickel chloride affects the expression of GCH1 mRNA CTD PMID:22546817 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression
increases expression
EXP
ISO
nickel chloride affects the expression of GCLC mRNA
nickel chloride results in increased expression of GCLC mRNA
CTD PMID:17547211 PMID:21111804 PMID:22110744 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP nickel chloride results in increased expression of GCLM mRNA CTD PMID:22110744 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO nickel chloride results in increased expression of GCNT3 mRNA CTD PMID:17547211 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 affects expression EXP nickel chloride affects the expression of GDE1 mRNA CTD PMID:22110744 NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO nickel chloride results in increased expression of GDF15 mRNA CTD PMID:17312168 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdf5 growth differentiation factor 5 affects expression EXP nickel chloride affects the expression of GDF5 mRNA CTD PMID:22546817 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Gemin4 gem (nuclear organelle) associated protein 4 decreases expression ISO nickel chloride results in decreased expression of GEMIN4 mRNA CTD PMID:17312168 NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431
Ensembl chr10:61,066,425...61,073,431
JBrowse link
G Ggcx gamma-glutamyl carboxylase decreases expression ISO nickel chloride results in decreased expression of GGCX mRNA CTD PMID:17547211 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP nickel chloride affects the expression of GJB1 mRNA CTD PMID:22110744 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gla galactosidase, alpha increases expression ISO nickel chloride results in increased expression of GLA mRNA CTD PMID:17547211 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664
JBrowse link
G Glrx glutaredoxin increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of GLRX mRNA
nickel chloride affects the expression of GLRX mRNA
CTD PMID:17547211 PMID:22110744 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Gmnn geminin, DNA replication inhibitor affects expression EXP nickel chloride affects the expression of GMNN mRNA CTD PMID:22546817 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
JBrowse link
G Gnaq G protein subunit alpha q affects expression EXP nickel chloride affects the expression of GNAQ mRNA CTD PMID:22546817 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 affects expression ISO nickel chloride affects the expression of GPAT3 mRNA CTD PMID:33774146 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 decreases expression ISO nickel chloride results in decreased expression of GPER1 mRNA CTD PMID:17547211 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gpi glucose-6-phosphate isomerase increases expression
multiple interactions
ISO nickel chloride results in increased expression of GPI1 mRNA
HIF1A affects the reaction [nickel chloride results in increased expression of GPI1 mRNA]
CTD PMID:12426141 PMID:12729255 PMID:12839937 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpr137b G protein-coupled receptor 137B increases expression
multiple interactions
ISO nickel chloride results in increased expression of GPR137B mRNA
HIF1A affects the reaction [nickel chloride results in increased expression of GPR137B mRNA]
CTD PMID:12729255 NCBI chr17:86,003,630...86,041,841
Ensembl chr17:85,966,921...86,041,835
JBrowse link
G Gpr146 G protein-coupled receptor 146 affects expression EXP nickel chloride affects the expression of GPR146 mRNA CTD PMID:22110744 NCBI chr12:15,251,936...15,267,217
Ensembl chr12:15,251,813...15,267,206
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP [[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased activity of GPT protein; [nickel chloride results in increased abundance of Nickel] which results in increased activity of GPT protein; Fatty Acids, Omega-3 inhibits the reaction [[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased activity of GPT protein] CTD PMID:31639282 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP nickel chloride affects the expression of GPX1 mRNA CTD PMID:22110744 PMID:22546817 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grb14 growth factor receptor bound protein 14 affects expression EXP nickel chloride affects the expression of GRB14 mRNA CTD PMID:22110744 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
JBrowse link
G Grn granulin precursor affects expression EXP nickel chloride affects the expression of GRN mRNA CTD PMID:22110744 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
affects expression
ISO
EXP
[nickel chloride results in increased phosphorylation of AKT1 protein] which results in decreased activity of and results in increased phosphorylation of GSK3B protein; nickel chloride promotes the reaction [Tretinoin results in increased phosphorylation of GSK3B protein]
nickel chloride affects the expression of GSK3B mRNA
CTD PMID:21837363 PMID:22546817 PMID:25614230 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression ISO nickel chloride results in decreased expression of GSTA3 mRNA CTD PMID:14645679 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression ISO nickel chloride results in decreased expression of GSTM2 mRNA CTD PMID:14645679 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstt1 glutathione S-transferase theta 1 decreases expression ISO nickel chloride results in decreased expression of GSTT1 mRNA CTD PMID:12729255 PMID:14645679 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gusb glucuronidase, beta affects expression
increases activity
EXP nickel chloride affects the expression of GUSB mRNA
nickel chloride results in increased activity of GUSB protein
CTD PMID:12028813 PMID:22110744 NCBI chr12:26,701,191...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Gys1 glycogen synthase 1 affects expression EXP nickel chloride affects the expression of GYS1 mRNA CTD PMID:22110744 NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292
JBrowse link
G H2ax H2A.X variant histone decreases expression
increases expression
increases phosphorylation
multiple interactions
ISO nickel chloride results in decreased expression of H2AX mRNA
nickel chloride results in increased expression of H2AX protein modified form
nickel chloride results in increased phosphorylation of H2AX protein
Acetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased phosphorylation of H2AX protein]]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased phosphorylation of H2AX protein]; cobaltous chloride promotes the reaction [nickel chloride results in increased phosphorylation of H2AX protein]; nickel chloride promotes the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein]
CTD PMID:17312168 PMID:22172632 PMID:28552779 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2bu1 H2B.U histone 1 decreases acetylation
increases ubiquitination
ISO nickel chloride results in decreased acetylation of H2BU1 protein
nickel chloride results in increased ubiquitination of H2BU1 protein
CTD PMID:16522665 NCBI chr10:43,732,737...43,733,484
Ensembl chr10:43,732,864...43,736,277
JBrowse link
G H3f4 H3.4 histone decreases acetylation
increases methylation
ISO nickel chloride results in decreased acetylation of H3-4 protein
nickel chloride results in increased methylation of H3-4 protein
CTD PMID:16522665 PMID:19371620 NCBI chr10:43,740,797...43,741,207 JBrowse link
G H4c3 H4 clustered histone 3 increases expression ISO nickel chloride results in increased expression of H4C3 mRNA CTD PMID:17547211
G H4f16 H4 histone 16 decreases acetylation ISO nickel chloride results in decreased acetylation of H4-16 protein CTD PMID:16522665
G Hadh hydroxyacyl-CoA dehydrogenase affects expression EXP nickel chloride affects the expression of HADH mRNA CTD PMID:22110744 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hao1 hydroxyacid oxidase 1 decreases expression EXP nickel chloride results in decreased expression of HAO1 mRNA CTD PMID:22110744 NCBI chr 3:121,757,400...121,828,721
Ensembl chr 3:121,771,836...121,828,721
JBrowse link
G Haus1 HAUS augmin-like complex, subunit 1 affects expression EXP nickel chloride affects the expression of HAUS1 mRNA CTD PMID:22546817 NCBI chr18:71,275,417...71,286,626
Ensembl chr18:71,273,537...71,286,660
JBrowse link
G Hcfc2 host cell factor C2 affects expression EXP nickel chloride affects the expression of HCFC2 mRNA CTD PMID:22546817 NCBI chr 7:20,983,986...21,019,826
Ensembl chr 7:20,991,017...21,019,801
JBrowse link
G Hdac3 histone deacetylase 3 affects expression EXP nickel chloride affects the expression of HDAC3 mRNA CTD PMID:22546817 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hdac7 histone deacetylase 7 affects expression EXP nickel chloride affects the expression of HDAC7 mRNA CTD PMID:22546817 NCBI chr 7:128,923,918...128,962,025
Ensembl chr 7:128,923,920...128,962,072
JBrowse link
G Hdc histidine decarboxylase affects expression EXP nickel chloride affects the expression of HDC mRNA CTD PMID:22110744 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hexb hexosaminidase subunit beta affects expression EXP nickel chloride affects the expression of HEXB mRNA CTD PMID:22110744 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
increases stability
affects response to substance
ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]; 2-amino-3-(4'-N,N-bis(2-chloroethyl)amino)phenylpropionic acid N-oxide inhibits the reaction [nickel chloride results in increased expression of and results in increased activity of HIF1A protein]; [nickel chloride co-treated with Tretinoin] results in increased expression of HIF1A protein; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]; Cycloheximide promotes the reaction [nickel chloride results in increased expression of HIF1A protein]; HIF1A mutant form inhibits the reaction [nickel chloride results in decreased expression of CDH1 protein]; HIF1A mutant form inhibits the reaction [nickel chloride results in increased expression of FN1 protein]; HIF1A protein affects the reaction [nickel chloride results in increased secretion of IL6 protein]; HIF1A protein promotes the reaction [nickel chloride results in increased expression of BNIP3 protein]; HIF1A protein promotes the reaction [nickel chloride results in increased expression of CA9 protein]; HIF1A protein promotes the reaction [nickel chloride results in increased expression of CDKN1A protein]; HIF1A protein promotes the reaction [nickel chloride results in increased expression of CDKN1B protein]; nickel chloride inhibits the reaction [HIF1A protein binds to HSP90AB1 protein]; nickel chloride inhibits the reaction [VHL protein binds to HIF1A protein]; nickel chloride promotes the reaction [HIF1A protein binds to ARNT protein]; nickel chloride promotes the reaction [HIF1A protein binds to CDH1 promoter]; nickel chloride results in increased expression of and affects the localization of HIF1A protein; nickel chloride results in increased expression of and results in increased activity of HIF1A protein; nickel chloride results in increased expression of and results in increased stability of HIF1A protein; nickel chloride results in increased stability of and affects the localization of HIF1A protein; nickel chloride results in increased stability of and results in increased expression of HIF1A protein; Rotenone inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]
nickel chloride results in increased stability of HIF1A protein
AKT1 protein affects the reaction [nickel chloride results in increased expression of HIF1A protein]; HIF1A affects the reaction [nickel chloride results in increased expression of AK4 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of ALDOA mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of ARNT mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of BNIP3 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of CCNG2 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of E2F1 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of EGLN1 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of ERO1A mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of GAPDH mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of GPI1 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of GPR137B mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of HK2 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of IER3 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of LDHA mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of MKNK1 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of NDRG1 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of P4HA2 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of PFKL mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of PGK1 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of PKM mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of PTK2 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of SLC2A1 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of TPI1 mRNA]; HIF1A protein affects the reaction [nickel chloride results in increased expression of GAPDH mRNA]; HIF1A protein affects the reaction [nickel chloride results in increased expression of GBE1 mRNA]; HIF1A protein affects the reaction [nickel chloride results in increased expression of NDRG1 mRNA]
HIF1A protein affects the susceptibility to nickel chloride
CTD PMID:10646848 PMID:12426141 PMID:12729255 PMID:12839937 PMID:14729612 More... NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor decreases expression ISO nickel chloride results in decreased expression of HIF1AN mRNA CTD PMID:16705796 NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A affects expression
increases expression
EXP
ISO
nickel chloride affects the expression of HIGD1A mRNA
nickel chloride results in increased expression of HIGD1A mRNA
CTD PMID:12839937 PMID:22110744 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression ISO nickel chloride results in increased expression of HILPDA mRNA CTD PMID:21455298 NCBI chr 4:57,871,076...57,875,206
Ensembl chr 4:57,871,110...57,874,557
JBrowse link
G Hip1 huntingtin interacting protein 1 affects expression EXP nickel chloride affects the expression of HIP1 mRNA CTD PMID:22110744 PMID:22546817 NCBI chr12:21,133,319...21,267,796
Ensembl chr12:21,133,406...21,267,725
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 affects expression EXP nickel chloride affects the expression of HIPK1 mRNA CTD PMID:22546817 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902
JBrowse link
G Hivep2 HIVEP zinc finger 2 increases expression ISO nickel chloride results in increased expression of HIVEP2 mRNA CTD PMID:17312168 NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993
JBrowse link
G Hk1 hexokinase 1 increases expression ISO nickel chloride results in increased expression of HK1 mRNA CTD PMID:12426141 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hk2 hexokinase 2 increases expression
multiple interactions
ISO nickel chloride results in increased expression of HK2 mRNA; nickel chloride results in increased expression of HK2 protein
2-amino-3-(4'-N,N-bis(2-chloroethyl)amino)phenylpropionic acid N-oxide inhibits the reaction [nickel chloride results in increased expression of HK2 mRNA]
Dinoprostone promotes the reaction [nickel chloride results in increased expression of HK2 mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of HK2 mRNA]
CTD PMID:12426141 PMID:12729255 PMID:12839937 PMID:21455298 PMID:23566959 More... NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO nickel chloride results in decreased expression of HMGCR mRNA CTD PMID:17312168 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 affects expression EXP nickel chloride affects the expression of HMGCS2 mRNA CTD PMID:22110744 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 affects expression EXP nickel chloride affects the expression of HMGN5 mRNA CTD PMID:22110744 NCBI chr  X:74,085,871...74,094,488 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
affects expression
increases expression
ISO
EXP
Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [lipopolysaccharide A results in increased expression of HMOX1 protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of HMOX1 mRNA]; nickel chloride promotes the reaction [lipopolysaccharide A results in increased expression of HMOX1 protein]; nickel chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of HMOX1 mRNA]
nickel chloride affects the expression of HMOX1 mRNA
CTD PMID:16806455 PMID:17312168 PMID:17547211 PMID:18830972 PMID:21111804 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hrk harakiri, BCL2 interacting protein affects expression EXP nickel chloride affects the expression of HRK mRNA CTD PMID:22546817 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 affects expression EXP nickel chloride affects the expression of HSD17B13 mRNA CTD PMID:22110744 NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO nickel chloride inhibits the reaction [HIF1A protein binds to HSP90AB1 protein] CTD PMID:29355601 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression
increases expression
ISO nickel chloride results in decreased expression of HSPA1A mRNA
nickel chloride results in increased expression of HSPA1A mRNA
CTD PMID:12426141 PMID:12839937 PMID:17312168
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO nickel chloride results in decreased expression of HSPA1B mRNA CTD PMID:17312168 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression
increases expression
ISO
EXP
nickel chloride results in decreased expression of HSPA8 mRNA
nickel chloride results in increased expression of HSPA8 protein
CTD PMID:15736156 PMID:17312168 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 affects expression EXP nickel chloride affects the expression of HSPA9 mRNA CTD PMID:22546817 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 affects expression EXP nickel chloride affects the expression of HSPB8 mRNA CTD PMID:22110744 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions
increases secretion
ISO nickel chloride results in increased expression of ICAM1 mRNA; nickel chloride results in increased expression of ICAM1 protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [nickel chloride results in increased expression of ICAM1 protein]; [nickel chloride results in increased phosphorylation of NFKBIA protein] inhibits the reaction [nickel chloride results in increased expression of ICAM1 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [nickel chloride results in increased expression of ICAM1 protein]; MYD88 mutant form inhibits the reaction [nickel chloride results in increased expression of ICAM1 protein]
nickel chloride results in increased secretion of ICAM1 protein
CTD PMID:15737199 PMID:17312168 PMID:19844976 PMID:24080332 PMID:33774146 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein affects expression EXP nickel chloride affects the expression of ID1 mRNA CTD PMID:22110744 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases activity ISO nickel chloride results in increased activity of IDH2 protein CTD PMID:17018869 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta affects expression EXP nickel chloride affects the expression of IDH3B mRNA CTD PMID:22546817 NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982
JBrowse link
G Ier2 immediate early response 2 increases expression ISO nickel chloride results in increased expression of IER2 mRNA CTD PMID:17547211 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
JBrowse link
G Ier3 immediate early response 3 multiple interactions
affects expression
increases expression
ISO
EXP
HIF1A affects the reaction [nickel chloride results in increased expression of IER3 mRNA]
nickel chloride affects the expression of IER3 mRNA
CTD PMID:12729255 PMID:22110744 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifi44l interferon-induced protein 44-like increases expression ISO nickel chloride results in increased expression of IFI44L mRNA CTD PMID:21455298 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 increases expression ISO nickel chloride results in increased expression of IFIH1 mRNA CTD PMID:17312168 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 affects expression EXP nickel chloride affects the expression of IFITM1 mRNA CTD PMID:22546817 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 affects expression EXP nickel chloride affects the expression of IFITM3 mRNA CTD PMID:22110744 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
JBrowse link
G Ifng interferon gamma multiple interactions ISO nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter]
[MAP2K6 protein results in increased susceptibility to nickel chloride] which results in increased expression of IFNG protein; nickel chloride promotes the reaction [[[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; NOS2 protein promotes the reaction [nickel chloride promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide]]
CTD PMID:8975779 PMID:21544193 PMID:21569788 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO nickel chloride results in increased expression of IFNGR1 mRNA CTD PMID:17312168 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Ifngr2 interferon gamma receptor 2 increases expression ISO nickel chloride results in increased expression of IFNGR2 mRNA CTD PMID:17312168 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 affects expression EXP nickel chloride affects the expression of IFRD1 mRNA CTD PMID:22110744 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IGF1 protein CTD PMID:18437699 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf2 insulin-like growth factor 2 affects expression EXP nickel chloride affects the expression of IGF2 mRNA CTD PMID:22546817 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO nickel chloride results in increased expression of IGFBP1 mRNA CTD PMID:21455298 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO nickel chloride results in increased expression of IGFBP3 mRNA CTD PMID:21455298 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO nickel chloride results in decreased expression of IGFBP4 mRNA CTD PMID:12839937 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Igfbpl1 insulin-like growth factor binding protein-like 1 affects expression EXP nickel chloride affects the expression of IGFBPL1 mRNA CTD PMID:22110744 NCBI chr 5:60,076,428...60,091,833
Ensembl chr 5:60,076,429...60,091,833
JBrowse link
G Igsf1 immunoglobulin superfamily, member 1 decreases expression ISO nickel chloride results in decreased expression of IGSF1 mRNA CTD PMID:17547211 NCBI chr  X:129,069,891...129,085,331
Ensembl chr  X:129,069,896...129,085,139
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects response to substance
increases phosphorylation
multiple interactions
ISO IKBKB affects the susceptibility to nickel chloride
nickel chloride results in increased phosphorylation of IKBKB protein
chrysin inhibits the reaction [nickel chloride results in increased phosphorylation of IKBKB protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [nickel chloride results in increased phosphorylation of IKBKB protein]; IKBKB gene mutant form inhibits the reaction [nickel chloride results in decreased expression of TP63 mRNA alternative form]; Quercetin inhibits the reaction [nickel chloride results in increased phosphorylation of IKBKB protein]; SC 514 inhibits the reaction [nickel chloride results in increased phosphorylation of IKBKB protein]
IKBKB affects the reaction [nickel chloride results in increased activity of PTGS2 promoter]
CTD PMID:16982623 PMID:21466819 PMID:30016632 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO nickel chloride results in decreased expression of IKBKE mRNA CTD PMID:21466819 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Il10 interleukin 10 affects expression
multiple interactions
increases expression
EXP
ISO
nickel chloride affects the expression of IL10 mRNA
Apigenin inhibits the reaction [nickel chloride results in increased expression of IL10 protein]; chrysin inhibits the reaction [nickel chloride results in increased expression of IL10 protein]; Curcumin inhibits the reaction [nickel chloride results in increased expression of IL10 protein]; Luteolin inhibits the reaction [nickel chloride results in increased expression of IL10 protein]; Quercetin inhibits the reaction [nickel chloride results in increased expression of IL10 protein]
nickel chloride results in increased expression of IL10 mRNA; nickel chloride results in increased expression of IL10 protein
[MAP2K6 protein results in increased susceptibility to nickel chloride] which results in increased expression of IL10 protein
CTD PMID:21544193 PMID:22546817 PMID:27427241 PMID:30016632 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 affects expression ISO nickel chloride affects the expression of IL13 mRNA CTD PMID:24670797 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il15 interleukin 15 multiple interactions ISO [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL15 protein CTD PMID:18437699 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il18 interleukin 18 affects expression EXP
ISO
nickel chloride affects the expression of IL18 mRNA CTD PMID:22546817 PMID:24670797 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il18r1 interleukin 18 receptor 1 increases expression ISO nickel chloride results in increased expression of IL18R1 mRNA CTD PMID:17312168 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
JBrowse link
G Il1a interleukin 1 alpha increases expression
decreases expression
multiple interactions
ISO nickel chloride results in increased expression of IL1A mRNA
nickel chloride results in decreased expression of IL1A protein
[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL1A protein
CTD PMID:11378323 PMID:17312168 PMID:18437699 PMID:23178550 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
affects expression
decreases expression
increases secretion
increases expression
ISO
EXP
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[Lipopolysaccharides co-treated with nickel chloride] results in increased secretion of IL1B protein]; [Lipopolysaccharides co-treated with nickel chloride] results in increased secretion of IL1B protein; CASP1 protein promotes the reaction [[Lipopolysaccharides co-treated with nickel chloride] results in increased secretion of IL1B protein]; Lipopolysaccharides promotes the reaction [nickel chloride results in increased expression of IL1B mRNA]; NLRP3 protein promotes the reaction [[Lipopolysaccharides co-treated with nickel chloride] results in increased secretion of IL1B protein]; PYCARD protein promotes the reaction [[Lipopolysaccharides co-treated with nickel chloride] results in increased secretion of IL1B protein]
nickel chloride affects the expression of IL1B mRNA
[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased expression of IL1B protein; [nickel chloride results in increased abundance of Nickel] which results in increased expression of IL1B protein; Fatty Acids, Omega-3 inhibits the reaction [[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased expression of IL1B protein]
nickel chloride results in decreased expression of IL1B mRNA
nickel chloride results in increased secretion of IL1B protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of IL1B protein]; [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein] which results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with nickel chloride] results in increased secretion of IL1B protein; [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein; [nickel chloride results in increased abundance of Nickel] which results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein; Apigenin inhibits the reaction [nickel chloride results in increased expression of IL1B protein]; chrysin inhibits the reaction [nickel chloride results in increased expression of IL1B protein]; Curcumin inhibits the reaction [nickel chloride results in increased expression of IL1B protein]; Luteolin inhibits the reaction [nickel chloride results in increased expression of IL1B protein]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; nickel chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [nickel chloride results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of IL1B protein]; Sodium inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]
nickel chloride results in increased expression of IL1B mRNA; nickel chloride results in increased expression of IL1B protein
CTD PMID:11378323 PMID:16687389 PMID:18437699 PMID:19844976 PMID:21569788 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL2 protein; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter] CTD PMID:18437699 PMID:21569788 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il27 interleukin 27 increases expression ISO nickel chloride results in increased expression of IL27 mRNA CTD PMID:30421605 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
JBrowse link
G Il36b interleukin 36, beta multiple interactions ISO nickel chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL36B mRNA] CTD PMID:23090859 NCBI chr 3:7,024,862...7,122,489
Ensembl chr 3:7,021,973...7,031,619
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL4 protein CTD PMID:18437699 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 increases secretion
multiple interactions
ISO nickel chloride results in increased secretion of IL5 protein
[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IL5 protein
CTD PMID:18437699 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
increases secretion
increases expression
decreases secretion
ISO Lipopolysaccharides promotes the reaction [nickel chloride results in increased expression of IL6 mRNA]
nickel chloride results in decreased expression of IL6 mRNA
nickel chloride results in increased secretion of IL6 protein
nickel chloride results in increased expression of IL6 mRNA; nickel chloride results in increased expression of IL6 protein
nickel chloride results in decreased secretion of IL6 protein
[nickel chloride results in increased abundance of Nickel] which results in increased expression of IL6 mRNA; Apigenin inhibits the reaction [nickel chloride results in increased expression of IL6 protein]; chrysin inhibits the reaction [nickel chloride results in increased expression of IL6 protein]; Curcumin inhibits the reaction [nickel chloride results in increased expression of IL6 protein]; HIF1A protein affects the reaction [nickel chloride results in increased secretion of IL6 protein]; Luteolin inhibits the reaction [nickel chloride results in increased expression of IL6 protein]; nickel chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [nickel chloride results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of IL6 mRNA]
CTD PMID:11378323 PMID:16687389 PMID:17312168 PMID:18437699 PMID:23090859 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilkap ILK associated serine/threonine phosphatase affects expression EXP nickel chloride affects the expression of ILKAP mRNA CTD PMID:22546817 NCBI chr 9:91,966,440...91,988,791
Ensembl chr 9:91,966,441...91,988,892
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO nickel chloride results in increased expression of INHBA mRNA CTD PMID:17312168 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D affects expression EXP nickel chloride affects the expression of INPP5D mRNA CTD PMID:22546817 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 increases expression ISO nickel chloride results in increased expression of IQSEC1 mRNA CTD PMID:26378417 NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172
JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 increases expression ISO nickel chloride results in increased expression of IRAK4 protein CTD PMID:21473897 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837
JBrowse link
G Irf2 interferon regulatory factor 2 increases expression ISO nickel chloride results in increased expression of IRF2 mRNA CTD PMID:17312168 NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024
JBrowse link
G Irf3 interferon regulatory factor 3 decreases expression
multiple interactions
ISO nickel chloride results in decreased expression of IRF3 mRNA
IRF3 protein inhibits the reaction [nickel chloride results in decreased expression of TP63 mRNA alternative form]
CTD PMID:21466819 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO nickel chloride results in decreased expression of IRF7 mRNA CTD PMID:21466819 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Iscu iron-sulfur cluster assembly enzyme decreases activity ISO nickel chloride results in decreased activity of ISCU protein CTD PMID:23727075 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression EXP nickel chloride affects the expression of ISG15 mRNA CTD PMID:22546817 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein increases expression ISO nickel chloride results in increased expression of ITGB3BP mRNA CTD PMID:17547211 NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704
JBrowse link
G Itgb8 integrin subunit beta 8 increases expression ISO nickel chloride results in increased expression of ITGB8 mRNA CTD PMID:17312168 NCBI chr 6:140,124,997...140,208,254
Ensembl chr 6:140,127,203...140,208,476
JBrowse link
G Itm2b integral membrane protein 2B affects expression EXP nickel chloride affects the expression of ITM2B mRNA CTD PMID:22546817 NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917
JBrowse link
G Jag1 jagged canonical Notch ligand 1 increases expression ISO nickel chloride results in increased expression of JAG1 mRNA CTD PMID:17312168 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G Jak2 Janus kinase 2 affects expression EXP nickel chloride affects the expression of JAK2 mRNA CTD PMID:22546817 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase increases expression
affects expression
EXP nickel chloride results in increased expression of JMJD6 mRNA
nickel chloride affects the expression of JMJD6 mRNA
CTD PMID:22110744 PMID:22546817 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects expression
multiple interactions
EXP
ISO
nickel chloride affects the expression of JUN mRNA
[nickel chloride results in increased expression of GADD45A protein] which results in decreased phosphorylation of and results in decreased expression of JUN protein
CTD PMID:22110744 PMID:23536762 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO nickel chloride results in increased expression of JUNB mRNA CTD PMID:12426141 PMID:12839937 PMID:17312168 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit affects expression EXP nickel chloride affects the expression of JUND mRNA CTD PMID:22546817 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kank4 KN motif and ankyrin repeat domains 4 affects expression EXP nickel chloride affects the expression of KANK4 mRNA CTD PMID:22110744 NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:113,402,468...113,465,555
JBrowse link
G Kat2b lysine acetyltransferase 2B affects expression EXP nickel chloride affects the expression of KAT2B mRNA CTD PMID:22546817 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
JBrowse link
G Katna1 katanin catalytic subunit A1 affects expression EXP nickel chloride affects the expression of KATNA1 mRNA CTD PMID:22546817 NCBI chr 1:2,202,501...2,244,132
Ensembl chr 1:2,202,490...2,244,131
JBrowse link
G Kctd15 potassium channel tetramerization domain containing 15 affects expression EXP nickel chloride affects the expression of KCTD15 mRNA CTD PMID:22110744 NCBI chr 1:87,258,658...87,271,979
Ensembl chr 1:87,258,658...87,273,497
JBrowse link
G Kdm3a lysine demethylase 3A affects expression
increases expression
multiple interactions
EXP
ISO
nickel chloride affects the expression of KDM3A mRNA
nickel chloride results in increased expression of KDM3A mRNA; nickel chloride results in increased expression of KDM3A protein
Ascorbic Acid inhibits the reaction [nickel chloride results in increased expression of KDM3A mRNA]; Ascorbic Acid inhibits the reaction [nickel chloride results in increased expression of KDM3A protein]
CTD PMID:17312168 PMID:21455298 PMID:22110744 PMID:22318714 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Kdm4b lysine demethylase 4B increases expression ISO nickel chloride results in increased expression of KDM4B mRNA CTD PMID:17312168 NCBI chr 9:1,158,737...1,237,228
Ensembl chr 9:1,158,752...1,236,543
JBrowse link
G Kdm6b lysine demethylase 6B increases expression ISO nickel chloride results in increased expression of KDM6B mRNA; nickel chloride results in increased expression of KDM6B protein CTD PMID:25427687 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794
JBrowse link
G Kdm7a lysine demethylase 7A increases expression ISO nickel chloride results in increased expression of KDM7A mRNA CTD PMID:21455298 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998
JBrowse link
G Khdc4 KH domain containing 4, pre-mRNA splicing factor decreases expression ISO nickel chloride results in decreased expression of KHDC4 mRNA CTD PMID:17312168 NCBI chr 2:174,149,059...174,177,816
Ensembl chr 2:174,149,141...174,177,504
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase affects expression ISO nickel chloride affects the expression of KIT mRNA CTD PMID:24670797 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Kitlg KIT ligand decreases secretion
multiple interactions
ISO nickel chloride results in decreased secretion of KITLG protein
[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of KITLG protein
CTD PMID:18437699 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klf10 Kruppel-like factor 10 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of KLF10 mRNA
nickel chloride affects the expression of KLF10 mRNA
CTD PMID:17547211 PMID:22546817 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Klf4 Kruppel like factor 4 increases expression ISO nickel chloride results in increased expression of KLF4 protein CTD PMID:26962057 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klf5 Kruppel-like factor 5 affects expression EXP nickel chloride affects the expression of KLF5 mRNA CTD PMID:22110744 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Klf6 Kruppel-like factor 6 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of KLF6 mRNA
nickel chloride affects the expression of KLF6 mRNA
CTD PMID:17547211 PMID:22110744 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Klhl24 kelch-like family member 24 increases expression ISO nickel chloride results in increased expression of KLHL24 mRNA CTD PMID:21455298 NCBI chr11:80,843,621...80,877,693
Ensembl chr11:80,846,755...80,877,636
JBrowse link
G Kmt2a lysine methyltransferase 2A affects expression
increases expression
EXP
ISO
nickel chloride affects the expression of KMT2A mRNA
nickel chloride results in increased expression of KMT2A mRNA
CTD PMID:22110744 PMID:26378417 NCBI chr 8:45,116,771...45,193,320
Ensembl chr 8:45,118,814...45,193,181
JBrowse link
G Kpna4 karyopherin subunit alpha 4 increases expression ISO nickel chloride results in increased expression of KPNA4 mRNA CTD PMID:17547211 NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081
JBrowse link
G Kynu kynureninase increases expression ISO nickel chloride results in increased expression of KYNU mRNA CTD PMID:17312168 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Lamc2 laminin subunit gamma 2 decreases expression ISO nickel chloride results in decreased expression of LAMC2 mRNA CTD PMID:12839937 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lcn2 lipocalin 2 affects expression EXP nickel chloride affects the expression of LCN2 mRNA CTD PMID:22546817 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Ldha lactate dehydrogenase A increases expression
multiple interactions
EXP
ISO
nickel chloride results in increased expression of LDHA mRNA
2-amino-3-(4'-N,N-bis(2-chloroethyl)amino)phenylpropionic acid N-oxide inhibits the reaction [nickel chloride results in increased expression of LDHA mRNA]
Dinoprostone promotes the reaction [nickel chloride results in increased expression of LDHA mRNA]; HIF1A affects the reaction [nickel chloride results in increased expression of LDHA mRNA]
CTD PMID:12426141 PMID:12729255 PMID:12839937 PMID:22110744 PMID:27452194 More... NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO nickel chloride results in decreased expression of LDLR mRNA CTD PMID:17312168 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 affects expression EXP nickel chloride affects the expression of LEF1 mRNA CTD PMID:22110744 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lep leptin multiple interactions ISO
EXP
[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of LEP protein
nickel chloride inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]
CTD PMID:10780946 PMID:18437699 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lgals2 galectin 2 affects expression EXP nickel chloride affects the expression of LGALS2 mRNA CTD PMID:22110744 NCBI chr 7:110,403,171...110,410,046
Ensembl chr 7:110,403,173...110,404,802
JBrowse link
G Lgals7 galectin 7 affects expression EXP nickel chloride affects the expression of LGALS7 mRNA CTD PMID:22546817 NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015
JBrowse link
G Lig4 DNA ligase 4 decreases expression ISO nickel chloride results in decreased expression of LIG4 mRNA CTD PMID:28472268 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Lin7c lin-7 homolog C, crumbs cell polarity complex component decreases expression ISO nickel chloride results in decreased expression of LIN7C mRNA CTD PMID:17312168 NCBI chr 3:96,406,825...96,414,137
Ensembl chr 3:96,406,813...96,417,728
JBrowse link
G Lipa lipase A, lysosomal acid type decreases expression ISO nickel chloride results in decreased expression of LIPA mRNA CTD PMID:17547211 NCBI chr 1:232,024,351...232,167,329
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor affects expression EXP nickel chloride affects the expression of LITAF mRNA CTD PMID:22546817 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO nickel chloride results in increased expression of HSPA6 mRNA CTD PMID:15287566 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Lox lysyl oxidase increases expression ISO nickel chloride results in increased expression of LOX mRNA CTD PMID:17312168 PMID:21455298 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Loxl2 lysyl oxidase-like 2 affects expression EXP nickel chloride affects the expression of LOXL2 mRNA CTD PMID:22110744 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
JBrowse link
G Lsp1 lymphocyte-specific protein 1 affects expression EXP nickel chloride affects the expression of LSP1 mRNA CTD PMID:22546817 NCBI chr 1:197,614,585...197,648,414
Ensembl chr 1:197,614,687...197,648,416
JBrowse link
G Lss lanosterol synthase decreases expression ISO nickel chloride results in decreased expression of LSS mRNA CTD PMID:17547211 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Ltb lymphotoxin beta increases expression ISO nickel chloride results in increased expression of LTB mRNA CTD PMID:17312168 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Luc7l3 LUC7-like 3 pre-mRNA splicing factor decreases expression ISO nickel chloride results in decreased expression of CROP mRNA CTD PMID:17312168 NCBI chr10:79,240,050...79,276,555
Ensembl chr10:79,240,563...79,276,538
JBrowse link
G Ly96 lymphocyte antigen 96 multiple interactions ISO nickel chloride results in increased activity of [TLR4 protein binds to LY96 protein] CTD PMID:25803856 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase affects expression EXP nickel chloride affects the expression of LYN mRNA CTD PMID:22546817 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Madd MAP-kinase activating death domain affects expression EXP nickel chloride affects the expression of MADD mRNA CTD PMID:22546817 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
JBrowse link
G Maff MAF bZIP transcription factor F increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of MAFF mRNA
nickel chloride affects the expression of MAFF mRNA
CTD PMID:17547211 PMID:22110744 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafk MAF bZIP transcription factor K affects expression EXP nickel chloride affects the expression of MAFK mRNA CTD PMID:22546817 NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions ISO nickel chloride promotes the reaction [Tretinoin results in increased expression of MAP2 mRNA] CTD PMID:25614230 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 affects expression EXP nickel chloride affects the expression of MAP2K1 mRNA CTD PMID:22110744 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 multiple interactions ISO GADD45A protein inhibits the reaction [nickel chloride results in increased activity of MAP2K3 protein] CTD PMID:23536762 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO GADD45A protein inhibits the reaction [nickel chloride results in increased activity of MAP2K4 protein] CTD PMID:23536762 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 affects expression
increases response to substance
multiple interactions
EXP
ISO
nickel chloride affects the expression of MAP2K6 mRNA
MAP2K6 protein results in increased susceptibility to nickel chloride
[incomplete Freund's adjuvant co-treated with Freund's Adjuvant co-treated with nickel chloride] results in increased expression of MAP2K6 mRNA; [incomplete Freund's adjuvant co-treated with Freund's Adjuvant co-treated with nickel chloride] results in increased phosphorylation of MAP2K6 protein; [MAP2K6 protein results in increased susceptibility to nickel chloride] which results in increased expression of IFNG protein; [MAP2K6 protein results in increased susceptibility to nickel chloride] which results in increased expression of IL10 protein; GADD45A protein inhibits the reaction [nickel chloride results in increased activity of MAP2K6 protein]
CTD PMID:21544193 PMID:22110744 PMID:23536762 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 multiple interactions ISO GADD45A protein inhibits the reaction [nickel chloride results in increased activity of MAP2K7 protein] CTD PMID:23536762 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 affects expression EXP nickel chloride affects the expression of MAP3K10 mRNA CTD PMID:22546817 NCBI chr 1:82,955,783...82,974,084
Ensembl chr 1:82,955,207...82,974,084
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 affects expression EXP nickel chloride affects the expression of MAP3K7 mRNA CTD PMID:22546817 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of MAP3K8 mRNA
nickel chloride affects the expression of MAP3K8 mRNA
CTD PMID:17312168 PMID:22546817 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO nickel chloride results in increased phosphorylation of MAPK1 protein
[nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of MAPK1 protein; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK1 protein]; Nifedipine inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK1 protein]
CTD PMID:25045119 PMID:30724446 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 affects expression EXP nickel chloride affects the expression of MAPK12 mRNA CTD PMID:22546817 NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664
JBrowse link
G Mapk13 mitogen activated protein kinase 13 affects expression EXP nickel chloride affects the expression of MAPK13 mRNA CTD PMID:22546817 NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO nickel chloride results in increased phosphorylation of MAPK14 protein CTD PMID:15737199 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects expression
increases phosphorylation
multiple interactions
EXP
ISO
nickel chloride affects the expression of MAPK3 mRNA
nickel chloride results in increased phosphorylation of MAPK3 protein
[nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of MAPK3 protein; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK3 protein]; Nifedipine inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK3 protein]
CTD PMID:22546817 PMID:25045119 PMID:30724446 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
EXP
ISO
pyrazolanthrone inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK8 protein]
MAPK8 affects the reaction [nickel chloride results in increased expression of PTGS2 mRNA]; MAPK8 affects the reaction [nickel chloride results in increased expression of PTGS2 protein]
CTD PMID:17065197 PMID:21843586 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 affects expression EXP nickel chloride affects the expression of MAPK8IP1 mRNA CTD PMID:22546817 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation
EXP pyrazolanthrone inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK9 protein] CTD PMID:21843586 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 affects expression EXP nickel chloride affects the expression of MAPRE1 mRNA CTD PMID:22546817 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983
JBrowse link
G Mars1 methionyl-tRNA synthetase 1 increases expression ISO nickel chloride results in increased expression of MARS1 mRNA CTD PMID:17312168 NCBI chr 7:63,121,142...63,138,550
Ensembl chr 7:63,121,142...63,138,495
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO nickel chloride results in decreased expression of MAT2A mRNA CTD PMID:17312168 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mbl2 mannose binding lectin 2 affects expression EXP nickel chloride affects the expression of MBL2 mRNA CTD PMID:22110744 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 increases expression ISO nickel chloride results in increased expression of MBNL2 mRNA CTD PMID:17312168 NCBI chr15:97,385,238...97,542,924
Ensembl chr15:97,385,244...97,542,937
JBrowse link
G Mboat1 membrane bound O-acyltransferase domain containing 1 affects expression EXP nickel chloride affects the expression of MBOAT1 mRNA CTD PMID:22110744 NCBI chr17:34,331,413...34,445,088
Ensembl chr17:34,331,422...34,445,088
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression
affects expression
multiple interactions
increases expression
ISO
EXP
nickel chloride results in decreased expression of MCL1 mRNA
nickel chloride affects the expression of MCL1 mRNA
TP53 protein affects the reaction [nickel chloride results in increased expression of MCL1 mRNA]
CTD PMID:17312168 PMID:22546817 PMID:23566959 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO nickel chloride results in decreased expression of MCM2 mRNA CTD PMID:17312168 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO nickel chloride results in decreased expression of MCM4 mRNA CTD PMID:17312168 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 affects expression EXP nickel chloride affects the expression of MCM5 mRNA CTD PMID:22546817 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 affects expression EXP nickel chloride affects the expression of MCM6 mRNA CTD PMID:22546817 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 affects expression EXP nickel chloride affects the expression of MDC1 mRNA CTD PMID:22546817 NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240
JBrowse link
G Mdh2 malate dehydrogenase 2 increases activity ISO nickel chloride results in increased activity of MDH2 protein CTD PMID:17018869 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
JBrowse link
G Mdk midkine affects expression EXP nickel chloride affects the expression of MDK mRNA CTD PMID:22546817 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
affects expression
increases expression
ISO
EXP
TP53 protein affects the reaction [nickel chloride results in increased expression of MDM2 mRNA]
nickel chloride affects the expression of MDM2 mRNA
CTD PMID:22546817 PMID:23566959 PMID:28552779 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mdm4 MDM4 regulator of p53 decreases expression
affects expression
ISO
EXP
nickel chloride results in decreased expression of MDM4 protein
nickel chloride affects the expression of MDM4 mRNA
CTD PMID:22546817 PMID:23566959 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226
JBrowse link
G Med13 mediator complex subunit 13 decreases expression ISO nickel chloride results in decreased expression of MED13 mRNA CTD PMID:17312168 NCBI chr10:71,086,978...71,176,535
Ensembl chr10:71,090,516...71,177,242
JBrowse link
G Men1 menin 1 affects expression EXP nickel chloride affects the expression of MEN1 mRNA CTD PMID:22546817 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase decreases expression ISO nickel chloride results in decreased expression of MERTK mRNA CTD PMID:17312168 NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
JBrowse link
G Mex3b mex-3 RNA binding family member B affects expression EXP nickel chloride affects the expression of MEX3B mRNA CTD PMID:22110744 NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354
JBrowse link
G Mgarp mitochondria-localized glutamic acid-rich protein affects expression EXP nickel chloride affects the expression of MGARP mRNA CTD PMID:22110744 NCBI chr 2:135,431,283...135,439,425
Ensembl chr 2:135,431,283...135,439,612
JBrowse link
G MGC105649 hypothetical LOC302884 increases expression ISO nickel chloride results in increased expression of C15ORF48 mRNA CTD PMID:21455298 NCBI chr 3:109,719,952...109,723,507
Ensembl chr 3:109,719,897...109,724,006
Ensembl chr 3:109,719,897...109,724,006
JBrowse link
G Mgll monoglyceride lipase affects expression EXP nickel chloride affects the expression of MGLL mRNA CTD PMID:22110744 NCBI chr 4:121,192,187...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Mir21 microRNA 21 multiple interactions
increases expression
ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [nickel chloride results in increased expression of MIR21 mRNA]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [nickel chloride results in increased expression of MIR21 mRNA]; [nickel chloride results in increased expression of MIR21 mRNA] which results in decreased expression of RECK protein; [nickel chloride results in increased expression of MIR21 mRNA] which results in decreased expression of SPRY2 protein CTD PMID:26026961 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir210 microRNA 210 increases expression ISO nickel chloride results in increased expression of MIR210 mRNA CTD PMID:24577088 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mix23 mitochondrial matrix import factor 23 affects expression EXP nickel chloride affects the expression of MIX23 mRNA CTD PMID:22110744 NCBI chr11:64,660,711...64,681,000
Ensembl chr11:64,660,711...64,681,000
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 multiple interactions ISO HIF1A affects the reaction [nickel chloride results in increased expression of MKNK1 mRNA] CTD PMID:12729255 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639
JBrowse link
G Mlh1 mutL homolog 1 affects expression
decreases expression
EXP
ISO
nickel chloride affects the expression of MLH1 mRNA
nickel chloride results in decreased expression of MLH1 mRNA; nickel chloride results in decreased expression of MLH1 protein
CTD PMID:22546817 PMID:28472268 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO nickel chloride results in increased expression of MMP2 protein CTD PMID:21473897 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions
increases activity
ISO nickel chloride results in increased expression of MMP9 protein
chrysin inhibits the reaction [nickel chloride results in increased expression of and results in increased activity of MMP9 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [nickel chloride results in increased expression of and results in increased activity of MMP9 protein]; nickel chloride results in increased expression of and results in increased activity of MMP9 protein; Quercetin inhibits the reaction [nickel chloride results in increased expression of and results in increased activity of MMP9 protein]; SC 514 inhibits the reaction [nickel chloride results in increased expression of and results in increased activity of MMP9 protein]
nickel chloride results in increased activity of MMP9 protein
CTD PMID:21473897 PMID:26962057 PMID:30016632 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Moap1 modulator of apoptosis 1 decreases expression ISO nickel chloride results in decreased expression of MOAP1 mRNA CTD PMID:17312168 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased activity of MPO protein; [nickel chloride results in increased abundance of Nickel] which results in increased activity of MPO protein; Fatty Acids, Omega-3 inhibits the reaction [[[nickel chloride results in increased abundance of Nickel] co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased activity of MPO protein] CTD PMID:31639282 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 decreases expression ISO nickel chloride results in decreased expression of MRPS6 mRNA CTD PMID:17312168 NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484
JBrowse link
G Mrs2 magnesium transporter MRS2 decreases expression ISO nickel chloride results in decreased expression of MRS2 mRNA CTD PMID:17312168 NCBI chr17:40,063,924...40,087,073
Ensembl chr17:40,063,962...40,081,887
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO nickel chloride results in decreased expression of MSMO1 mRNA CTD PMID:17312168 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression
ISO Carnitine inhibits the reaction [nickel chloride results in decreased expression of COX1 mRNA] CTD PMID:21419151 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 multiple interactions
decreases expression
ISO Carnitine inhibits the reaction [nickel chloride results in decreased expression of ND6 mRNA] CTD PMID:21419151 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mt1 metallothionein 1 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of MT1 mRNA
nickel chloride affects the expression of MT1A mRNA
CTD PMID:12729255 PMID:22110744 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
JBrowse link
G Mt2A metallothionein 2A affects expression
increases expression
EXP
ISO
nickel chloride affects the expression of MT2A mRNA
nickel chloride results in increased expression of MT2A mRNA
CTD PMID:22110744 PMID:26378417 PMID:28472268 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtch1 mitochondrial carrier 1 affects expression EXP nickel chloride affects the expression of MTCH1 mRNA CTD PMID:22546817 NCBI chr20:7,389,942...7,413,426
Ensembl chr20:7,389,949...7,413,426
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression ISO nickel chloride results in increased expression of MTHFD2 mRNA CTD PMID:17312168 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mtmr7 myotubularin related protein 7 affects expression EXP nickel chloride affects the expression of MTMR7 mRNA CTD PMID:22110744 NCBI chr16:51,641,225...51,732,212
Ensembl chr16:51,641,190...51,732,182
JBrowse link
G Mttp microsomal triglyceride transfer protein affects expression EXP nickel chloride affects the expression of MTTP mRNA CTD PMID:22110744 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO nickel chloride results in increased expression of MXI1 mRNA CTD PMID:17312168 PMID:21455298 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Mybl2 MYB proto-oncogene like 2 affects expression EXP nickel chloride affects the expression of MYBL2 mRNA CTD PMID:22546817 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects expression
increases expression
EXP
ISO
nickel chloride affects the expression of MYC mRNA
nickel chloride results in increased expression of MYC protein
CTD PMID:22110744 PMID:22546817 PMID:28552779 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mycbp2 MYC binding protein 2 affects expression EXP nickel chloride affects the expression of MYCBP2 mRNA CTD PMID:22110744 NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor affects expression EXP nickel chloride affects the expression of MYCL mRNA CTD PMID:22546817 NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor affects expression EXP nickel chloride affects the expression of MYCN mRNA CTD PMID:22546817 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression
multiple interactions
ISO nickel chloride results in increased expression of MYD88 mRNA; nickel chloride results in increased expression of MYD88 protein
chrysin inhibits the reaction [nickel chloride results in increased expression of MYD88 mRNA]; chrysin inhibits the reaction [nickel chloride results in increased expression of MYD88 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [nickel chloride results in increased expression of MYD88 protein]; MYD88 mutant form inhibits the reaction [nickel chloride results in increased expression of CXCL8 protein]; MYD88 mutant form inhibits the reaction [nickel chloride results in increased expression of ICAM1 protein]; Quercetin inhibits the reaction [nickel chloride results in increased expression of MYD88 mRNA]; Quercetin inhibits the reaction [nickel chloride results in increased expression of MYD88 protein]
CTD PMID:21473897 PMID:24080332 PMID:30016632 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit decreases expression ISO nickel chloride results in decreased expression of NAA10 mRNA CTD PMID:16705796 NCBI chr  X:151,656,056...151,661,304
Ensembl chr  X:151,656,056...151,661,252
JBrowse link
G Nabp1 nucleic acid binding protein 1 affects expression EXP nickel chloride affects the expression of NABP1 mRNA CTD PMID:22110744 NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase affects expression EXP nickel chloride affects the expression of NAMPT mRNA CTD PMID:22110744 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nav2 neuron navigator 2 increases expression ISO nickel chloride results in increased expression of NAV2 mRNA CTD PMID:17312168 NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337
JBrowse link
G Ncam1 neural cell adhesion molecule 1 multiple interactions ISO nickel chloride promotes the reaction [Tretinoin results in increased expression of NCAM1 mRNA]; nickel chloride promotes the reaction [Tretinoin results in increased expression of NCAM1 protein] CTD PMID:25614230 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions
increases expression
affects expression
ISO
EXP
[nickel chloride co-treated with VHL protein] results in increased expression of NDRG1 mRNA
nickel chloride results in increased expression of NDRG1 mRNA; nickel chloride results in increased expression of NDRG1 protein
[nickel chloride co-treated with Dactinomycin] results in increased stability of NDRG1 mRNA; AKT1 protein affects the reaction [nickel chloride results in increased expression of NDRG1 protein]; HIF1A affects the reaction [nickel chloride results in increased expression of NDRG1 mRNA]; HIF1A protein affects the reaction [nickel chloride results in increased expression of NDRG1 mRNA]
nickel chloride affects the expression of NDRG1 mRNA
CTD PMID:10646848 PMID:10910041 PMID:12729255 PMID:12767066 PMID:14729612 More... NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndrg2 NDRG family member 2 affects expression EXP nickel chloride affects the expression of NDRG2 mRNA CTD PMID:22110744 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Nek2 NIMA-related kinase 2 affects expression EXP nickel chloride affects the expression of NEK2 mRNA CTD PMID:22546817 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nek3 NIMA-related kinase 3 affects expression EXP nickel chloride affects the expression of NEK3 mRNA CTD PMID:22546817 NCBI chr16:69,867,020...69,892,477
Ensembl chr16:69,867,047...69,892,508
JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor affects expression EXP nickel chloride affects the expression of NF2 mRNA CTD PMID:22546817 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
affects localization
ISO Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of NFE2L2 protein]; lipopolysaccharide A promotes the reaction [nickel chloride affects the localization of NFE2L2 protein]; Lipopolysaccharides promotes the reaction [nickel chloride results in increased expression of NFE2L2 protein]; nickel chloride promotes the reaction [lipopolysaccharide A results in increased expression of NFE2L2 protein] CTD PMID:16806455 PMID:18437699 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated affects expression
increases expression
EXP
ISO
nickel chloride affects the expression of NFIL3 mRNA
nickel chloride results in increased expression of NFIL3 mRNA
CTD PMID:17312168 PMID:22110744 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression
multiple interactions
affects expression
ISO
EXP
nickel chloride results in increased expression of NFKB1 mRNA
[nickel chloride results in increased abundance of Nickel] which results in increased expression of NFKB1 protein; nickel chloride binds to and affects the localization of NFKB1 protein
nickel chloride affects the expression of NFKB1 mRNA
CTD PMID:17312168 PMID:22546817 PMID:23844176 PMID:30724446 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 increases expression ISO nickel chloride results in increased expression of NFKB2 mRNA CTD PMID:17312168 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression
increases phosphorylation
multiple interactions
increases expression
ISO nickel chloride results in decreased expression of NFKBIA mRNA
nickel chloride results in increased phosphorylation of NFKBIA protein
[nickel chloride results in increased phosphorylation of NFKBIA protein] inhibits the reaction [nickel chloride results in increased expression of CXCL8 protein]; [nickel chloride results in increased phosphorylation of NFKBIA protein] inhibits the reaction [nickel chloride results in increased expression of ICAM1 protein]; chrysin inhibits the reaction [nickel chloride results in increased phosphorylation of NFKBIA protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [nickel chloride results in increased phosphorylation of NFKBIA protein]; Quercetin inhibits the reaction [nickel chloride results in increased phosphorylation of NFKBIA protein]; SC 514 inhibits the reaction [nickel chloride results in increased phosphorylation of NFKBIA protein]
nickel chloride results in increased expression of NFKBIA mRNA
CTD PMID:16982623 PMID:17312168 PMID:17547211 PMID:24080332 PMID:25803856 More... NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfya nuclear transcription factor Y subunit alpha increases expression ISO nickel chloride results in increased expression of NFYA mRNA CTD PMID:17547211 NCBI chr 9:12,587,437...12,613,911
Ensembl chr 9:12,586,259...12,613,898
JBrowse link
G Nfyc nuclear transcription factor Y subunit gamma affects expression EXP nickel chloride affects the expression of NFYC mRNA CTD PMID:22546817 NCBI chr 5:134,336,802...134,405,372
Ensembl chr 5:134,336,808...134,405,377
JBrowse link
G Nhej1 nonhomologous end-joining factor 1 affects expression ISO nickel chloride affects the expression of NHEJ1 mRNA CTD PMID:28472268 NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 affects expression EXP nickel chloride affects the expression of NLRC4 mRNA CTD PMID:22546817 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 multiple interactions ISO nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in decreased expression of NLRP12 mRNA] CTD PMID:23090859 NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO NLRP3 protein promotes the reaction [[Lipopolysaccharides co-treated with nickel chloride] results in increased secretion of IL1B protein]
[nickel chloride results in increased abundance of Nickel] which results in increased expression of NLRP3 protein; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of NLRP3 protein]
CTD PMID:24158569 PMID:31943712 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 affects expression EXP nickel chloride affects the expression of NME3 mRNA CTD PMID:22110744 PMID:22546817 NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359
JBrowse link
G Nmt2 N-myristoyltransferase 2 increases expression EXP nickel chloride results in increased expression of NMT2 mRNA CTD PMID:24619124 NCBI chr17:74,917,833...74,964,788
Ensembl chr17:74,917,833...74,961,080
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 multiple interactions ISO nickel chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in decreased expression of NOD1 mRNA] CTD PMID:23090859 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nol3 nucleolar protein 3 affects expression EXP nickel chloride affects the expression of NOL3 mRNA CTD PMID:22546817 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO Acetylcysteine inhibits the reaction [nickel chloride results in decreased expression of NOS2 mRNA]
nickel chloride promotes the reaction [[[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; NOS2 protein promotes the reaction [nickel chloride promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide]]
CTD PMID:8975779 PMID:18830972 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO nickel chloride inhibits the reaction [fluoranthene results in increased expression of NOS3 protein]; nickel chloride inhibits the reaction [fluorene results in increased expression of NOS3 protein]; nickel chloride inhibits the reaction [naphthalene results in increased expression of NOS3 protein] CTD PMID:15183461 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch1 notch receptor 1 affects expression
increases expression
EXP
ISO
nickel chloride affects the expression of NOTCH1 mRNA
nickel chloride results in increased expression of NOTCH1 protein
CTD PMID:22546817 PMID:26962057 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nox1 NADPH oxidase 1 increases expression ISO nickel chloride results in increased expression of NOX1 protein CTD PMID:22648416 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
decreases expression
ISO nickel chloride inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]
nickel chloride results in decreased expression of NQO1 mRNA
CTD PMID:14645679 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO nickel chloride results in decreased expression of NR0B2 mRNA CTD PMID:17547211 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 affects expression EXP nickel chloride affects the expression of NR2F6 mRNA CTD PMID:22546817 NCBI chr16:18,046,012...18,053,914
Ensembl chr16:18,046,013...18,053,459
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression ISO nickel chloride results in increased expression of NR3C1 mRNA CTD PMID:17312168 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nradd neurotrophin receptor associated death domain affects expression EXP nickel chloride affects the expression of NRADD mRNA CTD PMID:22546817 NCBI chr 8:110,599,667...110,603,068
Ensembl chr 8:110,599,667...110,603,149
JBrowse link
G Nrg1 neuregulin 1 increases expression ISO nickel chloride results in increased expression of NRG1 mRNA CTD PMID:17312168 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nrp1 neuropilin 1 decreases expression ISO nickel chloride results in decreased expression of NRP1 mRNA CTD PMID:12839937 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Ntn1 netrin 1 affects expression EXP nickel chloride affects the expression of NTN1 mRNA CTD PMID:22546817 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
JBrowse link
G Nucb2 nucleobindin 2 decreases expression
affects expression
ISO
EXP
nickel chloride results in decreased expression of NUCB2 mRNA
nickel chloride affects the expression of NUCB2 mRNA
CTD PMID:17547211 PMID:22110744 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 affects expression EXP nickel chloride affects the expression of NUCKS1 mRNA CTD PMID:22546817 NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex affects expression EXP nickel chloride affects the expression of NUF2 mRNA CTD PMID:22546817 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Nup43 nucleoporin 43 decreases expression ISO nickel chloride results in decreased expression of NUP43 mRNA CTD PMID:17312168 NCBI chr 1:2,144,427...2,157,887
Ensembl chr 1:2,148,043...2,158,186
JBrowse link
G Oga O-GlcNAcase increases expression ISO nickel chloride results in increased expression of OGA mRNA CTD PMID:17312168 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
JBrowse link
G Ogdh oxoglutarate dehydrogenase affects expression EXP nickel chloride affects the expression of OGDH mRNA CTD PMID:22110744 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Ogfrl1 opioid growth factor receptor-like 1 increases expression ISO nickel chloride results in increased expression of OGFRL1 mRNA CTD PMID:17312168 NCBI chr 9:25,828,865...25,842,424
Ensembl chr 9:25,828,869...25,842,352
JBrowse link
G Olfml2a olfactomedin-like 2A affects expression EXP nickel chloride affects the expression of OLFML2A mRNA CTD PMID:22110744 NCBI chr 3:22,688,562...22,717,745
Ensembl chr 3:22,688,598...22,717,909
JBrowse link
G Optn optineurin increases expression ISO nickel chloride results in increased expression of OPTN mRNA CTD PMID:17312168 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251
JBrowse link
G P2rx2 purinergic receptor P2X 2 multiple interactions EXP nickel chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein] CTD PMID:16190872 NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891
JBrowse link
G P2ry2 purinergic receptor P2Y2 affects expression EXP nickel chloride affects the expression of P2RY2 mRNA CTD PMID:22110744 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression
affects expression
ISO
EXP
nickel chloride results in increased expression of P4HA1 mRNA
nickel chloride affects the expression of P4HA1 mRNA
CTD PMID:21455298 PMID:22110744 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 multiple interactions
increases expression
affects expression
ISO
EXP
HIF1A affects the reaction [nickel chloride results in increased expression of P4HA2 mRNA]
nickel chloride affects the expression of P4HA2 mRNA
CTD PMID:12426141 PMID:12729255 PMID:12839937 PMID:22110744 NCBI chr10:38,243,047...38,271,989
Ensembl chr10:38,243,139...38,287,314
JBrowse link
G Pank1 pantothenate kinase 1 affects expression EXP nickel chloride affects the expression of PANK1 mRNA CTD PMID:22110744 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
JBrowse link
G Pank3 pantothenate kinase 3 decreases expression ISO nickel chloride results in decreased expression of PANK3 mRNA CTD PMID:17312168 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955
JBrowse link
G Pard6a par-6 family cell polarity regulator alpha affects expression EXP nickel chloride affects the expression of PARD6A mRNA CTD PMID:22546817 NCBI chr19:33,589,583...33,591,900
Ensembl chr19:33,589,542...33,591,900
JBrowse link
G Parm1 prostate androgen-regulated mucin-like protein 1 affects expression EXP nickel chloride affects the expression of PARM1 mRNA CTD PMID:22546817 NCBI chr14:16,468,309...16,577,339
Ensembl chr14:16,468,459...16,577,314
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
EXP
ISO
alpha-Tocopherol inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]; fumonisin B1 inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]
[TP53 mutant form results in decreased susceptibility to nickel chloride] which results in decreased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]; cobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of PARP1 protein]; nickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]
CTD PMID:21828359 PMID:21843586 PMID:22172632 PMID:23566959 PMID:24448832 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 affects expression EXP nickel chloride affects the expression of PBLD mRNA CTD PMID:22110744 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pcgf5 polycomb group ring finger 5 affects expression EXP nickel chloride affects the expression of PCGF5 mRNA CTD PMID:22110744 NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315
JBrowse link
G Pclaf PCNA clamp associated factor affects expression EXP nickel chloride affects the expression of PCLAF mRNA CTD PMID:22110744 NCBI chr 8:66,420,673...66,432,568
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pctp phosphatidylcholine transfer protein affects expression EXP nickel chloride affects the expression of PCTP mRNA CTD