Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

go back to main search page
Accession:CHEBI:3374 term browser browse the term
Definition:A capsaicinoid that has formula C18H27NO3.
Synonyms:exact_synonym: (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide
 related_synonym: (E)-8-Methyl-N-vanillyl-6-nonenamide;   Formula=C18H27NO3;   InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+;   InChIKey=YKPUWZUDDOIDPM-SOFGYWHQSA-N;   Isodecenoic acid vanillylamide;   SMILES=COc1cc(CNC(=O)CCCC\\C=C\\C(C)C)ccc1O;   Zostrix;   trans-8-Methyl-N-vanillyl-6-nonenamide
 xref: BPDB:1630;   Beilstein:2816484;   CAS:404-86-4;   Drug_Central:3064;   KEGG:C06866;   KEGG:D00250
 xref_mesh: MESH:D002211
 xref: Wikipedia:Capsaicin

show annotations for term's descendants           Sort by:
capsaicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTR1B 5-hydroxytryptamine receptor 1B multiple interactions EXP HTR1B protein promotes the reaction [donitriptan results in decreased susceptibility to Capsaicin] CTD PMID:16880765 NCBI chr12:38,659,088...38,659,546 JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 multiple interactions
increases activity
EXP JYL 1421 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] CTD PMID:17392452 NCBI chr 9:47,404,987...47,443,871
Ensembl chr 9:47,404,972...47,431,926
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 400
    role 402
      biological role 400
        pharmacological role 162
          agonist 93
            TRPV1 agonist 2
              capsaicin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 400
    subatomic particle 400
      composite particle 402
        hadron 400
          baryon 400
            nucleon 400
              atomic nucleus 400
                atom 400
                  main group element atom 395
                    p-block element atom 395
                      carbon group element atom 382
                        carbon atom 383
                          organic molecular entity 381
                            organic group 311
                              organic divalent group 310
                                organodiyl group 310
                                  carbonyl group 310
                                    carbonyl compound 310
                                      carboxylic acid 275
                                        carboacyl group 215
                                          univalent carboacyl group 215
                                            carbamoyl group 213
                                              carboxamide 213
                                                monocarboxylic acid amide 183
                                                  fatty amide 2
                                                    capsaicinoid 2
                                                      capsaicin 2
paths to the root