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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:capsaicin
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Accession:CHEBI:3374 term browser browse the term
Definition:A capsaicinoid that has formula C18H27NO3.
Synonyms:exact_synonym: (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide
 related_synonym: (E)-8-Methyl-N-vanillyl-6-nonenamide;   Formula=C18H27NO3;   InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+;   InChIKey=YKPUWZUDDOIDPM-SOFGYWHQSA-N;   Isodecenoic acid vanillylamide;   SMILES=COc1cc(CNC(=O)CCCC\\C=C\\C(C)C)ccc1O;   Zostrix;   trans-8-Methyl-N-vanillyl-6-nonenamide
 xref: BPDB:1630;   Beilstein:2816484;   CAS:404-86-4;   Drug_Central:3064;   KEGG:C06866;   KEGG:D00250
 xref_mesh: MESH:D002211
 xref: Wikipedia:Capsaicin



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capsaicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
increases expression
increases response to substance
ISO 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; [Capsaicin results in increased expression of ABCA1 protein] which results in decreased uptake of Cholesterol; [Capsaicin results in increased expression of ABCA1 protein] which results in increased secretion of Cholesterol; APOE affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; Cyclosporine affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; KT 5720 inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]
ABCA1 results in increased susceptibility to Capsaicin
CTD PMID:21908651 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
decreases expression
multiple interactions
ISO
EXP
Capsaicin results in increased expression of ABCB1 mRNA; Capsaicin results in increased expression of ABCB1 protein
Capsaicin results in decreased expression of ABCB1A mRNA
Capsaicin affects the reaction [ABCB1 protein results in increased export of Digoxin]
CTD PMID:16674925 PMID:24013073 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B decreases expression EXP Capsaicin results in decreased expression of ABCB1B mRNA CTD PMID:24013073 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO Capsaicin results in increased expression of ABL1 mRNA CTD PMID:19502594 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression EXP Capsaicin results in decreased expression of ACACB mRNA CTD PMID:16278290 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Capsaicin results in increased expression of ACOX1 mRNA CTD PMID:18533110 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO Capsaicin results in decreased expression of ACSL3 mRNA CTD PMID:18533110 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases secretion
increases expression
ISO Capsaicin results in increased secretion of ADIPOQ protein
Capsaicin results in increased expression of ADIPOQ mRNA; Capsaicin results in increased expression of ADIPOQ protein
CTD PMID:17295509 PMID:17719033 PMID:19798065 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adra2a adrenoceptor alpha 2A decreases response to substance ISO ADRA2A results in decreased susceptibility to Capsaicin CTD PMID:15220790 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Aga aspartylglucosaminidase decreases expression EXP Capsaicin results in decreased expression of AGA mRNA CTD PMID:16278290 NCBI chr16:38,504,661...38,516,607
Ensembl chr16:38,504,663...38,516,606
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression EXP Capsaicin results in increased expression of AGTR1A mRNA CTD PMID:20349343 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Capsaicin inhibits the reaction [Methylcholanthrene results in increased activity of and results in increased localization of AHR protein] CTD PMID:21250977 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization ISO Capsaicin affects the localization of AIFM1 protein CTD PMID:20925121 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akirin2 akirin 2 increases expression EXP Capsaicin results in increased expression of AKIRIN2 mRNA CTD PMID:16278290 NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of AKR1A1 protein] CTD PMID:20359164 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of AKR7A3 protein] CTD PMID:20359164 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
increases phosphorylation
increases activity
multiple interactions
EXP
ISO
Capsaicin results in increased expression of AKT1 protein modified form
Capsaicin results in increased phosphorylation of AKT1 protein
Capsaicin results in increased activity of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Capsaicin co-treated with Oxygen deficiency co-treated with Oxygen] results in increased phosphorylation of AKT1 protein]; [Capsaicin co-treated with Oxygen deficiency co-treated with Oxygen] results in increased phosphorylation of AKT1 protein
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of AKT1 protein]; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein]; wortmannin inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein]
CTD PMID:16360265 PMID:17084039 PMID:17979524 PMID:19011674 PMID:19059400 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin increases expression ISO Capsaicin results in increased expression of ALB protein CTD PMID:9537786 PMID:18991268 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 decreases expression EXP Capsaicin results in decreased expression of ALDH3A1 mRNA CTD PMID:16278290 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
decreases activity
EXP [Capsaicin co-treated with Curcumin] results in decreased activity of ALOX5 protein
Capsaicin results in decreased activity of ALOX5 protein
CTD PMID:16956363 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 decreases expression EXP Capsaicin results in decreased expression of AMHR2 mRNA CTD PMID:16278290 NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258
JBrowse link
G Amn amnion associated transmembrane protein multiple interactions
increases expression
EXP AMN protein inhibits the reaction [Capsaicin results in increased expression of SST protein]; AMN protein inhibits the reaction [Capsaicin results in increased expression of TAC1 protein]
Capsaicin results in increased expression of AMN protein
CTD PMID:16938409 NCBI chr 6:130,311,372...130,318,815
Ensembl chr 6:130,311,372...130,318,815
JBrowse link
G Angpt1 angiopoietin 1 increases expression ISO Capsaicin results in increased expression of ANGPT1 mRNA CTD PMID:21310942 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Angpt2 angiopoietin 2 increases expression ISO Capsaicin results in increased expression of ANGPT2 mRNA CTD PMID:21310942 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Capsaicin results in increased expression of APAF1 mRNA CTD PMID:19502594 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apob apolipoprotein B increases expression EXP Capsaicin results in increased expression of APOB mRNA CTD PMID:16278290 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO Capsaicin results in decreased expression of APOC1 mRNA CTD PMID:18533110 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO APOE affects the reaction [Capsaicin results in decreased expression of LRP1 protein]; APOE affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; Capsaicin inhibits the reaction [[APOE affects the susceptibility to Dietary Fats] which affects the abundance of Cholesterol]; Capsaicin inhibits the reaction [[APOE affects the susceptibility to Dietary Fats] which affects the abundance of Triglycerides] CTD PMID:21908651 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Aqp1 aquaporin 1 increases response to substance ISO AQP1 results in increased susceptibility to Capsaicin CTD PMID:20018876 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Ar androgen receptor increases expression
multiple interactions
ISO Capsaicin results in increased expression of AR protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of AR protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of AR protein]; Capsaicin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Capsaicin inhibits the reaction [Dihydrotestosterone results in increased expression of AR protein]; capsazepine inhibits the reaction [Capsaicin results in increased expression of AR protein]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of AR protein]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin results in increased expression of AR protein]
CTD PMID:16540674 PMID:19059400 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Areg amphiregulin multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA] CTD PMID:20660715 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 increases expression EXP Capsaicin results in increased expression of ARPP19 mRNA CTD PMID:16278290 NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression ISO Capsaicin results in decreased expression of ARRDC4 mRNA CTD PMID:33512557 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO ATF3 mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; Capsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein] CTD PMID:20110283 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
affects localization
increases expression
ISO Cycloheximide inhibits the reaction [Capsaicin results in increased expression of ATF4 protein]
Capsaicin affects the localization of ATF4 protein
CTD PMID:18533110 PMID:19139269 PMID:20925121 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atg16l1 autophagy related 16-like 1 decreases expression EXP Capsaicin results in decreased expression of ATG16L1 mRNA CTD PMID:20349343 NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529
JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression
ISO ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein]; ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of PRKDC protein]
Capsaicin results in increased expression of ATG5 protein
CTD PMID:22226932 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atm ATM serine/threonine kinase increases activity
multiple interactions
increases expression
increases phosphorylation
ISO Capsaicin results in increased activity of ATM protein
3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein]; ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein]; Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein
Capsaicin results in increased expression of ATM mRNA
Capsaicin results in increased phosphorylation of ATM protein
CTD PMID:19502594 PMID:22226932 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 affects metabolic processing
decreases expression
EXP Capsaicin affects the metabolism of ATP2A2 protein
Capsaicin results in decreased expression of ATP2A2 protein modified form
CTD PMID:18037908 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 decreases expression EXP Capsaicin results in decreased expression of ATP6AP1 mRNA CTD PMID:16278290 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Capsaicin results in increased expression of BAD mRNA CTD PMID:19502594 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO Capsaicin results in increased expression of BAG3 mRNA CTD PMID:19502594 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases activity
increases expression
ISO Capsaicin results in increased activity of BAK1 protein
Capsaicin results in increased expression of BAK1 mRNA
CTD PMID:17295509 PMID:19502594 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
affects localization
increases activity
ISO TP53 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]; TRPV6 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]
Capsaicin results in increased expression of BAX; Capsaicin results in increased expression of BAX mRNA; Capsaicin results in increased expression of BAX protein
Capsaicin affects the localization of BAX protein
Capsaicin results in increased activity of BAX protein
CTD PMID:16540674 PMID:17292493 PMID:17295509 PMID:19002586 PMID:19331147 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcan brevican decreases expression EXP Capsaicin results in decreased expression of BCAN mRNA CTD PMID:16278290 NCBI chr 2:173,454,479...173,467,717
Ensembl chr 2:173,454,482...173,467,460
JBrowse link
G Bcl10 BCL10, immune signaling adaptor increases expression ISO Capsaicin results in increased expression of BCL10 mRNA CTD PMID:19502594 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance
increases expression
decreases expression
ISO BCL2 protein results in decreased susceptibility to Capsaicin
Capsaicin results in increased expression of BCL2 mRNA
Capsaicin results in decreased expression of BCL2 protein
Capsaicin results in decreased expression of BCL2; Capsaicin results in decreased expression of BCL2 protein
CTD PMID:9580328 PMID:11275362 PMID:15595419 PMID:17295509 PMID:17306913 More... NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
increases expression
ISO Capsaicin results in decreased expression of BCL2L1 protein
Capsaicin results in increased expression of BCL2L1 mRNA
CTD PMID:17505005 PMID:19502594 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 increases expression ISO Capsaicin results in increased expression of BCLAF1 mRNA CTD PMID:19502594 NCBI chr 1:15,088,436...15,117,666 JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA] CTD PMID:22264228 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions EXP
ISO
Capsaicin inhibits the reaction [[KNG1 protein alternative form binds to and results in increased activity of BDKRB2 protein] which results in increased abundance of Inositol Phosphates]
BDKRB2 affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; BDKRB2 affects the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]
CTD PMID:15363968 PMID:17347322 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
affects expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of BDNF protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of BDNF protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of BDNF protein] CTD PMID:22150557 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 increases expression EXP Capsaicin results in increased expression of BECN1 mRNA CTD PMID:20349343 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
multiple interactions
increases expression
ISO Capsaicin results in increased cleavage of BID protein
Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of BID protein]
Capsaicin results in increased expression of BID mRNA
CTD PMID:19502594 PMID:22200406 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO Capsaicin results in increased expression of BIRC2 mRNA CTD PMID:19502594 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
multiple interactions
ISO Capsaicin results in decreased expression of BIRC5; Capsaicin results in decreased expression of BIRC5 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in decreased expression of BIRC5 protein]; BIRC5 results in decreased activity of [Capsaicin co-treated with TNFSF10 protein]
CTD PMID:17505005 PMID:19002586 PMID:19939880 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bnip2 BCL2 interacting protein 2 increases expression ISO Capsaicin results in increased expression of BNIP2 mRNA CTD PMID:19502594 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO Capsaicin results in decreased expression of BNIP3 mRNA CTD PMID:19502594 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression ISO Capsaicin results in decreased expression of BNIP3L mRNA CTD PMID:19502594 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 decreases expression EXP Capsaicin results in decreased expression of CACNG3 mRNA CTD PMID:16278290 NCBI chr 1:177,201,990...177,296,473
Ensembl chr 1:177,201,288...177,297,024
JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression
increases secretion
decreases expression
multiple interactions
affects response to substance
ISO
EXP
Capsaicin results in increased expression of CALCA mRNA; Capsaicin results in increased expression of CALCA protein
Capsaicin results in increased secretion of CALCA protein
Capsaicin results in decreased expression of CALCA mRNA; Capsaicin results in decreased expression of CALCA protein
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; [Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein; [Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein; [Capsaicin results in decreased susceptibility to safranal] which results in decreased secretion of CALCA protein; botulinum toxin type D inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; butaprost promotes the reaction [Capsaicin results in increased secretion of CALCA protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium affects the reaction [Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]]; Calcium affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Capsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of CALCA mRNA]; Capsaicin inhibits the reaction [monophosphoryl lipid A results in increased expression of CALCA mRNA]; Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]; Capsaicin inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; Capsaicin promotes the reaction [Phenol results in decreased expression of CALCA protein]; Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]; capsazepine inhibits the reaction [Capsaicin results in increased expression of CALCA protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Carbon Dioxide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; chelerythrine inhibits the reaction [Capsaicin results in increased expression of CALCA protein]; Dinoprostone promotes the reaction [Capsaicin results in increased secretion of CALCA protein]; Enkephalin, Ala(2)-MePhe(4)-Gly(5)- inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; epothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of CALCA protein]; mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Nefopam inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; neuropeptide Y, Leu(31)-Pro(34)- inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; NGF protein promotes the reaction [Capsaicin results in increased expression of CALCA protein]; nociceptin (1-13) amide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; OPRL1 protein promotes the reaction [nociceptin (1-13) amide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Paclitaxel inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Plant Extracts inhibits the reaction [Capsaicin results in decreased expression of CALCA protein]; Plant Extracts inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Polyphenols inhibits the reaction [Capsaicin results in decreased expression of CALCA protein]; Polyphenols inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; PPP3CA protein affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; TRPV1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]
CALCA protein alternative form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; capsazepine inhibits the reaction [Capsaicin results in increased expression of CALCA mRNA]
CALCA protein affects the susceptibility to Capsaicin
[Capsaicin co-treated with Ethanol] results in increased expression of CALCA protein; CALCA protein affects the reaction [Capsaicin results in decreased susceptibility to Ethanol]; CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]; CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 protein]; CALCA protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; CALCA protein promotes the reaction [Capsaicin results in decreased expression of CASP3 protein]; CALCA protein promotes the reaction [Capsaicin results in increased expression of IGF1 mRNA]; CALCA protein promotes the reaction [Capsaicin results in increased expression of IGF1 protein]; CNR1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]; rimabotulinumtoxinB inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]
CTD PMID:2462184 PMID:3412491 PMID:7473211 PMID:8971780 PMID:11738242 More... NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calcb calcitonin-related polypeptide, beta increases expression
decreases activity
multiple interactions
increases secretion
ISO
EXP
Capsaicin results in increased expression of CALCB mRNA
CALCB protein alternative form results in decreased activity of Capsaicin
Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]]
capsazepine inhibits the reaction [Capsaicin results in increased expression of CALCB mRNA]
Capsaicin results in increased secretion of CALCB protein
CTD PMID:9932722 PMID:14764656 PMID:17434803 PMID:18584893 NCBI chr 1:168,966,465...168,970,125
Ensembl chr 1:168,966,465...168,970,125
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Capsaicin results in increased phosphorylation of and results in increased expression of CAMK2A protein CTD PMID:12019337 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression
multiple interactions
EXP Capsaicin results in increased expression of CAMP protein
Glyoxal promotes the reaction [Capsaicin results in increased expression of CAMP protein]
CTD PMID:29496360 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543
JBrowse link
G Casp2 caspase 2 multiple interactions ISO [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP2 protein CTD PMID:19939880 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 increases expression
affects activity
increases activity
multiple interactions
increases cleavage
affects expression
decreases expression
ISO
EXP
Capsaicin results in increased expression of CASP3 protein
Capsaicin affects the activity of CASP3 protein
Capsaicin results in increased activity of CASP3 protein
Capsaicin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased activity of CASP3 protein]
Capsaicin results in increased cleavage of CASP3 protein
[ND1 gene mutant form results in increased susceptibility to Capsaicin] which results in increased activity of CASP3 protein; Capsaicin promotes the reaction [resveratrol results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TRPV1 protein results in increased activity of CASP3 protein]; Capsaicin results in increased cleavage of and results in increased activity of CASP3 protein; capsazepine inhibits the reaction [Capsaicin results in increased cleavage of and results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP3 protein]; EUK-134 inhibits the reaction [Capsaicin results in increased cleavage of CASP3 protein]; resveratrol promotes the reaction [Capsaicin results in increased activity of CASP3 protein]
Capsaicin affects the expression of CASP3 protein
Capsaicin results in decreased expression of CASP3 protein
CALCA protein promotes the reaction [Capsaicin results in decreased expression of CASP3 protein]
CTD PMID:11275362 PMID:16125681 PMID:16477149 PMID:17295509 PMID:17306913 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases activity
multiple interactions
increases expression
ISO
EXP
Capsaicin results in increased activity of CASP4 protein
Capsaicin results in increased cleavage of and results in increased activity of CASP4 protein
Capsaicin results in increased expression of CASP4 mRNA
CTD PMID:19139269 PMID:19699254 PMID:20349343 PMID:20371669 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 multiple interactions ISO [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP6 protein CTD PMID:19939880 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP7 protein
Capsaicin results in increased activity of CASP7 protein
CTD PMID:19139269 PMID:19699254 PMID:19855437 PMID:19939880 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases activity
decreases expression
multiple interactions
increases expression
ISO Capsaicin results in increased activity of CASP8 protein
Capsaicin results in decreased expression of CASP8 protein
[Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP8 protein; Capsaicin promotes the reaction [resveratrol results in decreased expression of CASP8 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP8 protein]; resveratrol promotes the reaction [Capsaicin results in decreased expression of CASP8 protein]
Capsaicin results in increased expression of CASP8 mRNA
CTD PMID:19502594 PMID:19846903 PMID:19939880 PMID:22200406 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases cleavage
increases activity
multiple interactions
increases expression
affects expression
ISO
EXP
Capsaicin results in increased cleavage of CASP9 protein
Capsaicin results in increased activity of CASP9 protein
[Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP9 protein; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP9 protein]; CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP9 protein]; EUK-134 inhibits the reaction [Capsaicin results in increased cleavage of CASP9 protein]
Capsaicin results in increased expression of CASP9 protein
Capsaicin affects the expression of CASP9 protein
Capsaicin results in increased expression of CASP9 mRNA
CTD PMID:16125681 PMID:16477149 PMID:19502594 PMID:19699254 PMID:19855437 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP3 protein]; CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP9 protein]; CAT protein inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]
Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased expression of CAT]
CTD PMID:14871840 PMID:18023135 PMID:18338764 PMID:21647434 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cck cholecystokinin multiple interactions ISO
EXP
[Capsaicin co-treated with CCK protein alternative form] results in increased expression of TAC1 protein; Capsaicin inhibits the reaction [CCK protein alternative form results in decreased expression of NGF mRNA]; Capsaicin promotes the reaction [CCK protein alternative form results in increased expression of NGF protein]
Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:10683199 PMID:22508518 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression EXP Capsaicin results in increased expression of CCL19 mRNA CTD PMID:20349343 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
decreases secretion
increases expression
EXP
ISO
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL2 protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of CCL2 protein]
Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
Capsaicin results in decreased expression of CCL2 mRNA; Capsaicin results in decreased expression of CCL2 protein
Capsaicin results in decreased secretion of CCL2 protein
capsazepine inhibits the reaction [Capsaicin results in decreased secretion of CCL2 protein]; troglitazone promotes the reaction [Capsaicin results in decreased secretion of CCL2 protein]
Capsaicin results in increased expression of CCL2 mRNA; Capsaicin results in increased expression of CCL2 protein
CTD PMID:17719033 PMID:19798065 PMID:20349343 PMID:22150557 PMID:30244119 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions
EXP Capsaicin results in increased expression of CCL20 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL20 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL20 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCL20 protein]
CTD PMID:22150557 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL22 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL22 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCL22 protein] CTD PMID:22150557 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression
ISO
EXP
Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]
CTD PMID:21745629 PMID:22150557 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Capsaicin results in decreased expression of CCNA2 protein CTD PMID:19939880 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Capsaicin results in decreased expression of CCNB1 protein CTD PMID:19939880 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Capsaicin results in decreased expression of CCND1 protein CTD PMID:17505005 PMID:19855437 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Capsaicin results in increased expression of CCNL1 mRNA CTD PMID:20349343 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 increases expression
multiple interactions
EXP Capsaicin results in increased expression of CCR4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCR4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCR4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCR4 protein]
CTD PMID:22150557 NCBI chr 8:114,176,256...114,182,155
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Cd46 CD46 molecule increases expression EXP Capsaicin results in increased expression of CD46 mRNA CTD PMID:16278290 NCBI chr13:106,575,586...106,606,325 JBrowse link
G Cd68 Cd68 molecule decreases expression ISO Capsaicin results in decreased expression of CD68 mRNA CTD PMID:19798065 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cd80 Cd80 molecule increases expression
multiple interactions
EXP Capsaicin results in increased expression of CD80 protein
[Naproxen co-treated with Sumatriptan] affects the reaction [Capsaicin results in increased expression of CD80 protein]; Naproxen affects the reaction [Capsaicin results in increased expression of CD80 protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of CD80 protein]
CTD PMID:22150557 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd8b CD8b molecule increases expression EXP Capsaicin results in increased expression of CD8B mRNA CTD PMID:16278290 NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553
JBrowse link
G Cdc14a cell division cycle 14A increases expression EXP Capsaicin results in increased expression of CDC14A mRNA CTD PMID:20349343 NCBI chr 2:204,225,540...204,380,927
Ensembl chr 2:204,225,540...204,380,927
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP Capsaicin results in increased expression of CDK1 mRNA CTD PMID:20349343 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Capsaicin results in decreased expression of CDK2 protein CTD PMID:20646592 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression EXP Capsaicin results in decreased expression of CDK4 mRNA CTD PMID:16278290 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression
ISO Capsaicin results in increased expression of CDKN1A mRNA; Capsaicin results in increased expression of CDKN1A protein
Capsaicin results in decreased expression of CDKN1A protein
CTD PMID:16540674 PMID:19502594 PMID:20646592 PMID:22226932 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
decreases expression
ISO Capsaicin results in increased expression of CDKN1B
Capsaicin results in increased expression of CDKN1B protein
Capsaicin results in decreased expression of CDKN1B protein
CTD PMID:19855437 PMID:20069556 PMID:22226932 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO Capsaicin results in increased expression of CDKN2A mRNA CTD PMID:18533110 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions
ISO
EXP
Capsaicin results in decreased expression of CEBPA protein
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of CEBPA mRNA]
CTD PMID:17295509 PMID:20359164 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases activity
ISO [CEBPB protein binds to GDF15 promoter] promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]; Capsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein]; CEBPB mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; CEBPB protein promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]
Capsaicin results in increased activity of CEBPB protein
[Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]
CTD PMID:20110283 PMID:21250977 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cfl1 cofilin 1 multiple interactions ISO [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] which results in increased import of Calcium; Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein; Egtazic Acid inhibits the reaction [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] CTD PMID:17303079 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression
decreases expression
ISO Capsaicin results in increased expression of CFLAR mRNA
Capsaicin results in decreased expression of CFLAR protein alternative form
CTD PMID:19502594 PMID:19939880 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cftr CF transmembrane conductance regulator increases activity ISO Capsaicin results in increased activity of CFTR protein; Capsaicin results in increased activity of CFTR protein mutant form CTD PMID:15155835 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO Capsaicin results in increased expression of CHEK2 mRNA CTD PMID:19502594 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator multiple interactions ISO Capsaicin inhibits the reaction [IFNG protein results in increased expression of CIITA mRNA] CTD PMID:19825429 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Cilk1 ciliogenesis associated kinase 1 increases expression
multiple interactions
EXP Capsaicin results in increased expression of CILK1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CILK1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CILK1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CILK1 protein]
CTD PMID:22150557 NCBI chr 8:78,984,075...79,042,695
Ensembl chr 8:78,984,258...79,042,691
JBrowse link
G Cldn1 claudin 1 increases expression EXP Capsaicin results in increased expression of CLDN1 mRNA CTD PMID:16278290 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Clec2d C-type lectin domain family 2, member D decreases expression EXP Capsaicin results in decreased expression of CLEC2D mRNA CTD PMID:16278290 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527
JBrowse link
G Clk1 CDC-like kinase 1 increases expression EXP Capsaicin results in increased expression of CLK1 mRNA CTD PMID:20349343 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases activity
affects response to substance
ISO
EXP
CNR1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]
Capsaicin results in increased activity of CNR1 protein
CNR1 protein affects the susceptibility to Capsaicin
CTD PMID:11408034 PMID:18987195 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cntf ciliary neurotrophic factor increases expression
multiple interactions
EXP Capsaicin results in increased expression of CNTF protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CNTF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CNTF protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CNTF protein]
CTD PMID:22150557 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877
JBrowse link
G Cntfr ciliary neurotrophic factor receptor multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CNTFR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CNTFR protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CNTFR protein] CTD PMID:22150557 NCBI chr 5:56,823,448...56,861,075
Ensembl chr 5:56,823,965...56,841,392
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression ISO Capsaicin results in increased expression of COL18A1 mRNA CTD PMID:21310942 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP Capsaicin results in increased expression of COL1A1 mRNA CTD PMID:20349343 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression EXP Capsaicin results in increased expression of COL3A1 mRNA CTD PMID:20349343 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression EXP Capsaicin results in increased expression of COX4I1 protein CTD PMID:18079164 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression ISO Capsaicin results in increased expression of COX5A protein CTD PMID:18991268 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 increases expression EXP Capsaicin results in increased expression of COX6A1 mRNA CTD PMID:16278290 NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions
increases expression
ISO
EXP
Capsaicin promotes the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of CPT1A mRNA]
Capsaicin results in increased expression of CPT1A mRNA
CTD PMID:20359164 PMID:21745629 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; NPC 15437 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; Ro 31-8425 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; U 0126 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein] CTD PMID:15385614 PMID:15631885 PMID:16159392 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Csf2 colony stimulating factor 2 increases expression
multiple interactions
EXP Capsaicin results in increased expression of CSF2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CSF2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CSF2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CSF2 protein]
CTD PMID:22150557 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 increases phosphorylation ISO Capsaicin results in increased phosphorylation of CSNK2A1 protein CTD PMID:20510015 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Csnk2b casein kinase 2 beta increases phosphorylation ISO Capsaicin results in increased phosphorylation of CSNK2B protein CTD PMID:20510015 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
EXP Capsaicin results in increased expression of CTNNB1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CTNNB1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CTNNB1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CTNNB1 protein]
CTD PMID:22150557 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 affects expression
multiple interactions
EXP Capsaicin affects the expression of CX3CL1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of CX3CL1 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of CX3CL1 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of CX3CL1 protein]
CTD PMID:22150557 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
multiple interactions
EXP Capsaicin results in increased expression of CXCL10 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]
CTD PMID:22150557 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
EXP Capsaicin results in increased expression of CXCL2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]
CTD PMID:22150557 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression
multiple interactions
EXP Capsaicin results in increased expression of CXCL5 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL5 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL5 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL5 protein]
CTD PMID:22150557 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression
multiple interactions
EXP Capsaicin results in increased expression of CXCR4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCR4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCR4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCR4 protein]
CTD PMID:22150557 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO
EXP
CYBB protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]
CYBB mutant form inhibits the reaction [Capsaicin results in increased expression of STAT1 protein]
CTD PMID:18203709 PMID:20712533 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects expression
ISO [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Capsaicin affects the expression of and affects the activity of CYP1A1 protein; Capsaicin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]
Capsaicin affects the expression of CYP1A1 mRNA
CTD PMID:19449198 PMID:21250977 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Capsaicin results in decreased activity of CYP1A2 protein CTD PMID:22375877 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 decreases expression EXP Capsaicin results in decreased expression of CYP2A2 mRNA CTD PMID:16278290 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity ISO Capsaicin results in decreased activity of CYP2C9 protein CTD PMID:22375877 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO Capsaicin results in decreased activity of CYP2C19 protein CTD PMID:22375877 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Capsaicin results in decreased activity of CYP2D6 protein CTD PMID:22375877 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Capsaicin results in increased expression of CYP2E1 CTD PMID:22375877 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression
decreases activity
EXP
ISO
Capsaicin results in decreased expression of CYP3A2 mRNA; Capsaicin results in decreased expression of CYP3A2 protein
Capsaicin results in decreased activity of CYP3A4 protein
CTD PMID:20388821 PMID:24013073 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression EXP Capsaicin results in decreased expression of CYP3A23-3A1 mRNA; Capsaicin results in decreased expression of CYP3A23-3A1 protein CTD PMID:24013073 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
affects localization
EXP
ISO
Capsaicin results in increased expression of DDIT3 protein
Capsaicin affects the localization of DDIT3 protein
Capsaicin analog results in increased expression of DDIT3 mRNA; Capsaicin results in increased expression of DDIT3; Capsaicin results in increased expression of DDIT3 mRNA; Capsaicin results in increased expression of DDIT3 protein
CTD PMID:18533110 PMID:19139269 PMID:19285962 PMID:19331147 PMID:19699254 More... NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Defb2 defensin beta 2 multiple interactions
increases expression
EXP Glyoxal promotes the reaction [Capsaicin results in increased expression of DEFB2 protein] CTD PMID:29496360 NCBI chr16:70,231,945...70,245,784
Ensembl chr16:70,231,945...70,245,784
JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases expression ISO Capsaicin results in decreased expression of DFFA CTD PMID:16188123 NCBI chr 5:159,540,718...159,553,639
Ensembl chr 5:159,540,715...159,553,633
JBrowse link
G Dpp3 dipeptidylpeptidase 3 decreases expression EXP Capsaicin results in decreased expression of DPP3 mRNA CTD PMID:20349343 NCBI chr 1:202,204,683...202,228,501
Ensembl chr 1:202,204,693...202,228,541
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO [NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]] which results in increased expression of DUSP1 protein; DUSP1 mutant form promotes the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased secretion of CXCL8 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased secretion of IL6 protein] CTD PMID:22171160 NCBI chr10:16,680,489...16,683,276 JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Capsaicin results in increased expression of E2F1 mRNA CTD PMID:19502594 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Edn1 endothelin 1 decreases activity
multiple interactions
ISO EDN1 protein results in decreased activity of Capsaicin
EDN1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; FR 139317 inhibits the reaction [EDN1 protein results in decreased activity of Capsaicin]
CTD PMID:9932722 PMID:19429182 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of EEF2 protein] CTD PMID:20359164 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Egf epidermal growth factor multiple interactions
decreases expression
decreases activity
ISO
EXP
Capsaicin inhibits the reaction [EGF results in increased activity of MMP2 protein]; Capsaicin inhibits the reaction [EGF results in increased activity of MMP9 protein]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP14]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP2]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP9]; Capsaicin inhibits the reaction [EGF results in increased localization of FOS protein]; Capsaicin inhibits the reaction [EGF results in increased localization of JUN protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of AKT1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of EGFR protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK3 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK8 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK9 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of PTK2 protein]
Capsaicin results in decreased expression of EGF protein
Capsaicin results in decreased activity of EGF protein
CTD PMID:9324159 PMID:14521749 PMID:21462327 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression
increases phosphorylation
ISO
EXP
AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of EGFR protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein]; RTKI cpd inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein]
Capsaicin results in decreased expression of EGFR protein
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; EGFR gene mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]
CTD PMID:14521749 PMID:19855437 PMID:20619260 PMID:20660715 PMID:21462327 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 increases expression EXP Capsaicin results in increased expression of EGR1 mRNA CTD PMID:20349343 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO
EXP
Capsaicin results in increased phosphorylation of EIF2A protein CTD PMID:18533110 PMID:19285962 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Capsaicin results in increased phosphorylation of EIF2S1 protein CTD PMID:19139269 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eln elastin increases expression EXP Capsaicin results in increased expression of ELN mRNA CTD PMID:16278290 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Eno2 enolase 2 multiple interactions ISO Capsaicin inhibits the reaction [Benzo(a)pyrene results in increased expression of ENO2 protein] CTD PMID:19449198 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Enox2 ecto-NOX disulfide-thiol exchanger 2 increases response to substance ISO ENOX2 results in increased susceptibility to Capsaicin CTD PMID:15706060 NCBI chr  X:128,270,941...128,593,074
Ensembl chr  X:128,271,074...128,593,039
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; 3-(2-methoxybenzylamino)-2-phenylpiperidine inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; [[Capsaicin results in increased chemical synthesis of Lysophosphatidylcholines] which results in increased secretion of Lysophosphatidylcholines] promotes the reaction [ENPP2 results in increased chemical synthesis of lysophosphatidic acid]; [ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid; arachidonyltrifluoromethane inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; bisindolylmaleimide I inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; Dizocilpine Maleate inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; U 0126 inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; xestospongin C inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid] CTD PMID:19014389 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Epor erythropoietin receptor increases expression ISO Capsaicin results in increased expression of EPOR mRNA; Capsaicin results in increased expression of EPOR protein CTD PMID:17603282 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects expression
decreases expression
ISO Capsaicin affects the expression of ERBB2 mRNA
Capsaicin results in decreased expression of ERBB2 protein
CTD PMID:19502594 PMID:19855437 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO Capsaicin results in increased expression of ERN1 protein CTD PMID:19139269 PMID:19699254 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of ERRFI1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of ERRFI1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of ERRFI1 protein] CTD PMID:22150557 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Etfa electron transfer flavoprotein subunit alpha multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of ETFA protein] CTD PMID:20359164 NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969
JBrowse link
G Exosc8 exosome component 8 decreases expression EXP Capsaicin results in decreased expression of EXOSC8 mRNA CTD PMID:16278290 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G F2 coagulation factor II affects expression EXP Capsaicin affects the expression of F2 protein CTD PMID:8285224 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] CTD PMID:16793902 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression
multiple interactions
ISO
EXP
Capsaicin results in decreased expression of FABP4 mRNA
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of FABP4 mRNA]; Capsaicin inhibits the reaction [Dietary Fats results in increased expression of FABP4 protein]
CTD PMID:18533110 PMID:20359164 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO Capsaicin results in decreased expression of FABP5 mRNA CTD PMID:18533110 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fadd Fas associated via death domain increases expression
multiple interactions
EXP Capsaicin results in increased expression of FADD protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FADD protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FADD protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FADD protein]
CTD PMID:22150557 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fam162a family with sequence similarity 162, member A decreases expression EXP Capsaicin results in decreased expression of FAM162A mRNA CTD PMID:16278290 NCBI chr11:64,680,937...64,711,239
Ensembl chr11:64,680,323...64,711,239
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
affects expression
ISO
EXP
Capsaicin results in increased expression of FAS mRNA; Capsaicin results in increased expression of FAS protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FAS protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FAS protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FAS protein]
Capsaicin promotes the reaction [resveratrol results in increased expression of FAS protein]
Capsaicin affects the expression of FAS mRNA
CTD PMID:19502594 PMID:19846903 PMID:21310942 PMID:22150557 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FASLG protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FASLG protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FASLG protein] CTD PMID:22150557 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Capsaicin results in increased expression of FDFT1 mRNA CTD PMID:33512557 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase increases expression EXP Capsaicin results in increased expression of FDPS mRNA CTD PMID:16278290 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression EXP Capsaicin results in decreased expression of FGF2 protein CTD PMID:14521749 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 multiple interactions
affects expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of FGFBP1 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of FGFBP1 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of FGFBP1 protein] CTD PMID:22150557 NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression EXP Capsaicin results in decreased expression of FGFR1 protein CTD PMID:14521749 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgl1 fibrinogen-like 1 multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FGL1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FGL1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FGL1 protein] CTD PMID:22150557 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression EXP Capsaicin results in decreased expression of FKBP4 mRNA CTD PMID:20349343 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Fmod fibromodulin increases expression EXP Capsaicin results in increased expression of FMOD mRNA CTD PMID:20349343 NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133
JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha increases expression EXP Capsaicin results in increased expression of FNTA mRNA CTD PMID:16278290 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression
multiple interactions
ISO
EXP
Capsaicin results in decreased expression of FOS mRNA
Capsaicin results in increased expression of FOS protein
Capsaicin results in increased expression of FOS; Capsaicin results in increased expression of FOS mRNA; Capsaicin results in increased expression of FOS protein
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [Capsaicin results in increased expression of FOS]; 2-amino-4-phosphonobutyric acid inhibits the reaction [Capsaicin results in increased expression of FOS]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased expression of FOS]; Capsaicin inhibits the reaction [8-sulfocholecystokinin octapeptide results in increased expression of FOS protein]; Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; Capsaicin inhibits the reaction [GHRL results in increased expression of FOS protein]; Capsaicin inhibits the reaction [Hydrochloric Acid results in increased expression of FOS protein]; Melatonin inhibits the reaction [Capsaicin results in increased expression of FOS protein]
Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; Capsaicin inhibits the reaction [EGF results in increased localization of FOS protein]
Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS mRNA]; Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]; GHRL protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; GRK6 mutant form promotes the reaction [Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]]; HTR1B protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; HTR1D protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; HTR1F protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; LY 344864 inhibits the reaction [Capsaicin results in increased expression of FOS protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FOS protein]
CTD PMID:1922926 PMID:9372230 PMID:9580328 PMID:10401552 PMID:10749792 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression
EXP N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Capsaicin results in increased expression of FOSL1 protein] CTD PMID:20054487 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxa1 forkhead box A1 decreases expression ISO Capsaicin results in decreased expression of FOXA1 mRNA CTD PMID:18533110 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxe3 forkhead box E3 increases expression EXP Capsaicin results in increased expression of FOXE3 mRNA CTD PMID:16278290 NCBI chr 5:128,445,594...128,446,454
Ensembl chr 5:128,445,594...128,446,454
JBrowse link
G Fstl1 follistatin-like 1 multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FSTL1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FSTL1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FSTL1 protein] CTD PMID:22150557 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
JBrowse link
G Fxyd6 FXYD domain-containing ion transport regulator 6 increases expression EXP Capsaicin results in increased expression of FXYD6 mRNA CTD PMID:16278290 NCBI chr 8:45,679,054...45,705,958
Ensembl chr 8:45,678,885...45,705,958
JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho3 increases expression EXP Capsaicin results in increased expression of GABRR3 mRNA CTD PMID:16278290 NCBI chr11:40,902,812...40,955,263
Ensembl chr11:40,902,812...40,955,263
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Capsaicin results in increased expression of GADD45A mRNA CTD PMID:19502594 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions
increases expression
decreases response to substance
EXP
ISO
GAL protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]
Capsaicin results in increased expression of GAL mRNA
GAL protein results in decreased susceptibility to Capsaicin
CTD PMID:8971780 PMID:17999197 PMID:18553211 PMID:19112407 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Galr2 galanin receptor 2 increases expression EXP Capsaicin results in increased expression of GALR2 mRNA CTD PMID:18553211 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression
multiple interactions
ISO
EXP
Capsaicin results in increased expression of GAPDH protein
Capsaicin inhibits the reaction [Dietary Fats results in increased expression of GAPDH protein]
CTD PMID:18991268 PMID:20359164 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gast gastrin increases secretion
decreases secretion
EXP Capsaicin results in increased secretion of GAST protein
Capsaicin results in decreased secretion of GAST protein
CTD PMID:8093880 PMID:19208342 PMID:19296048 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
JBrowse link
G Gata1 GATA binding protein 1 increases expression ISO Capsaicin results in increased expression of GATA1 mRNA CTD PMID:17603282 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gcg glucagon multiple interactions ISO Capsaicin inhibits the reaction [Deoxyglucose results in increased secretion of GCG protein] CTD PMID:1378463 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gch1 GTP cyclohydrolase 1 affects response to substance ISO GCH1 gene SNP affects the susceptibility to Capsaicin CTD PMID:19081190 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions
increases phosphorylation
increases expression
ISO [CEBPB protein binds to GDF15 promoter] promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]; ATF3 mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; CEBPB mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; CEBPB protein promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]; GSK3B mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]
Capsaicin results in increased phosphorylation of GDF15 protein
CTD PMID:20110283 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions
ISO
EXP
Capsaicin results in increased expression of GFAP mRNA
Capsaicin results in increased expression of GFAP protein
7-nitroindazole inhibits the reaction [Capsaicin results in increased expression of GFAP protein]; [7-nitroindazole co-treated with pimagedine] promotes the reaction [Capsaicin results in increased expression of GFAP protein]; Capsaicin inhibits the reaction [IL6 protein results in increased expression of GFAP mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]; pimagedine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]
CTD PMID:18405923 PMID:19285962 PMID:20826152 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gfra1 GDNF family receptor alpha 1 affects expression
multiple interactions
EXP Capsaicin affects the expression of GFRA1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of GFRA1 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of GFRA1 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of GFRA1 protein]
CTD PMID:22150557 NCBI chr 1:257,315,682...257,552,004 JBrowse link
G Gfra2 GDNF family receptor alpha 2 affects expression
multiple interactions
EXP Capsaicin affects the expression of GFRA2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of GFRA2 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of GFRA2 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of GFRA2 protein]
CTD PMID:22150557 NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
JBrowse link
G Gh1 growth hormone 1 decreases secretion
increases expression
multiple interactions
EXP Capsaicin results in decreased secretion of GH protein
Capsaicin results in increased expression of GH1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of GH1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of GH1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of GH1 protein]
CTD PMID:12360474 PMID:22150557 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Ghr growth hormone receptor increases expression
multiple interactions
EXP Capsaicin results in increased expression of GHR protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of GHR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of GHR protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of GHR protein]
CTD PMID:22150557 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions
decreases activity
ISO
EXP
GHRL protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]
Capsaicin results in decreased activity of GHRL protein
Capsaicin inhibits the reaction [GHRL results in increased expression of FOS protein]
CTD PMID:12360474 PMID:15177919 PMID:18202139 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Gjb6 gap junction protein, beta 6 increases expression EXP Capsaicin results in increased expression of GJB6 mRNA CTD PMID:20349343 NCBI chr15:31,284,562...31,295,010
Ensembl chr15:31,284,419...31,294,582
JBrowse link
G Glp1r glucagon-like peptide 1 receptor decreases expression EXP Capsaicin results in decreased expression of GLP1R mRNA CTD PMID:22031786 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
JBrowse link
G Glud1 glutamate dehydrogenase 1 increases expression ISO Capsaicin results in increased expression of GLUD1 protein CTD PMID:18991268 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP Capsaicin inhibits the reaction [ferric sulfate results in increased activity of GOT1 protein]; Capsaicin inhibits the reaction [Iron results in increased activity of GOT1 protein] CTD PMID:16956363 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpr132 G protein-coupled receptor 132 decreases expression ISO Capsaicin results in decreased expression of GPR132 mRNA CTD PMID:19602228 NCBI chr 6:131,924,061...131,943,327
Ensembl chr 6:131,924,160...131,942,168
JBrowse link
G Gpr176 G protein-coupled receptor 176 decreases expression EXP Capsaicin results in decreased expression of GPR176 mRNA CTD PMID:16278290 NCBI chr 3:105,236,794...105,337,664
Ensembl chr 3:105,236,795...105,337,226
JBrowse link
G Gpr4 G protein-coupled receptor 4 decreases expression ISO Capsaicin results in decreased expression of GPR4 mRNA CTD PMID:19602228 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Capsaicin inhibits the reaction [ferric sulfate results in increased activity of GPT protein]; Capsaicin inhibits the reaction [Iron results in increased activity of GPT protein] CTD PMID:16956363 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO Capsaicin inhibits the reaction [Ethanol results in decreased expression of GPX1 mRNA] CTD PMID:18926900 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO Capsaicin inhibits the reaction [Ethanol results in decreased expression of GPX4 mRNA] CTD PMID:18926900 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 increases phosphorylation
multiple interactions
EXP Capsaicin results in increased phosphorylation of GRIA1 protein
KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of GRIA1 protein]
CTD PMID:12019337 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
increases phosphorylation
increases expression
EXP N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN1 protein]; phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in increased expression of GRIN1 protein modified form] CTD PMID:17317010 PMID:20054487 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases phosphorylation
multiple interactions
EXP Capsaicin results in increased phosphorylation of GRIN2B protein
capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN2B protein]; Excitatory Amino Acid Antagonists inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN2B protein]
CTD PMID:18577691 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 multiple interactions
decreases response to substance
ISO GRK6 mutant form promotes the reaction [Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]]
GRK6 results in decreased susceptibility to Capsaicin
CTD PMID:18687398 NCBI chr17:9,177,018...9,192,644
Ensembl chr17:9,177,019...9,192,644
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Capsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein]; GSK3B mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA] CTD PMID:20110283 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of GSR protein]; Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased expression of GSR] CTD PMID:18023135 PMID:18338764 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Capsaicin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA] CTD PMID:15313406 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gtf2h2 general transcription factor IIH subunit 2 decreases expression EXP Capsaicin results in decreased expression of GTF2H2 mRNA CTD PMID:16278290 NCBI chr 2:31,623,752...31,652,697
Ensembl chr 2:31,624,678...31,652,592
JBrowse link
G Gypa glycophorin A increases expression ISO Capsaicin results in increased expression of GYPA mRNA CTD PMID:17603282 NCBI chr19:27,450,311...27,465,940 JBrowse link
G Gzma granzyme A multiple interactions
increases expression
ISO Capsaicin results in increased expression of and results in increased secretion of GZMA protein
Capsaicin results in increased expression of GZMA mRNA
CTD PMID:21310942 NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493
JBrowse link
G H2ax H2A.X variant histone increases localization ISO Capsaicin results in increased localization of H2AX protein CTD PMID:22226932 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2bc1 H2B clustered histone 1 decreases expression EXP Capsaicin results in decreased expression of H2BC1 mRNA CTD PMID:16278290 NCBI chr17:41,172,041...41,172,510 JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions ISO Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of H6PD protein] CTD PMID:18338764 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Hbb hemoglobin subunit beta increases expression ISO Capsaicin results in increased expression of HBB-B1 mRNA CTD PMID:17603282 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of HBEGF mRNA CTD PMID:20660715 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hbg1 hemoglobin subunit gamma 1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of HBG1 protein] CTD PMID:20359164 NCBI chr 1:158,271,993...158,273,371
Ensembl chr 1:158,271,873...158,273,425
JBrowse link
G Hcrt hypocretin neuropeptide precursor multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of HCRT protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of HCRT protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of HCRT protein] CTD PMID:22150557 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210
JBrowse link
G Hdac2 histone deacetylase 2 increases expression EXP Capsaicin results in increased expression of HDAC2 mRNA CTD PMID:16278290 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 increases expression EXP Capsaicin results in increased expression of HEY2 mRNA CTD PMID:16278290 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Capsaicin results in increased expression of HIF1A mRNA CTD PMID:12242509 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hip1r huntingtin interacting protein 1 related decreases expression EXP Capsaicin results in decreased expression of HIP1R mRNA CTD PMID:20349343 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734
JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP Capsaicin results in increased expression of HMGB2 mRNA CTD PMID:16278290 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Capsaicin results in increased expression of HMOX1 mRNA; Capsaicin results in increased expression of HMOX1 protein
Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of HMOX1 mRNA]
Capsaicin inhibits the reaction [monophosphoryl lipid A results in increased expression of HMOX1 mRNA]; Capsaicin promotes the reaction [Hydrochloric Acid results in increased expression of HMOX1 protein]
CTD PMID:11738242 PMID:17979524 PMID:18617559 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression EXP Capsaicin results in increased expression of HNRNPA1 mRNA CTD PMID:20349343 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hpcal1 hippocalcin-like 1 increases expression EXP Capsaicin results in increased expression of HPCAL1 mRNA CTD PMID:16278290 NCBI chr 6:40,478,182...40,584,721
Ensembl chr 6:40,478,208...40,584,687
JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression ISO Capsaicin results in increased expression of HRAS mRNA CTD PMID:9461043 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression EXP Capsaicin results in increased expression of HSF1 mRNA CTD PMID:24746025 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression
multiple interactions
ISO
EXP
Capsaicin results in increased expression of HSP90B1 protein
Capsaicin inhibits the reaction [Dietary Fats results in increased expression of HSP90B1 protein]
CTD PMID:18991268 PMID:20359164 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
increases localization
ISO Capsaicin results in increased expression of HSPA5; Capsaicin results in increased expression of HSPA5 protein
Capsaicin results in increased localization of HSPA5 protein
CTD PMID:19139269 PMID:19331147 PMID:19699254 PMID:21859781 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of HSP27 protein] CTD PMID:20359164 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B multiple interactions ISO HTR1B protein inhibits the reaction [Capsaicin results in increased expression of FOS protein] CTD PMID:12110114 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D multiple interactions ISO HTR1D protein inhibits the reaction [Capsaicin results in increased expression of FOS protein] CTD PMID:12110114 NCBI chr 5:148,655,979...148,676,534
Ensembl chr 5:148,674,495...148,675,619
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F multiple interactions ISO HTR1F protein inhibits the reaction [Capsaicin results in increased expression of FOS protein] CTD PMID:12110114 NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A decreases activity ISO Capsaicin results in decreased activity of HTR3A protein CTD PMID:26456648 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B decreases expression EXP Capsaicin results in decreased expression of HTR3B mRNA CTD PMID:16278290 NCBI chr 8:49,279,291...49,308,444
Ensembl chr 8:49,279,173...49,308,444
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP Capsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of ICAM1] CTD PMID:20600813 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ide insulin degrading enzyme multiple interactions
affects expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of IDE protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of IDE protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of IDE protein] CTD PMID:22150557 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
JBrowse link
G Ifng interferon gamma decreases expression
multiple interactions
ISO
EXP
Capsaicin results in decreased expression of IFNG
Capsaicin inhibits the reaction [[IFNG protein results in increased abundance of Nitric Oxide] which results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [IFNG protein results in increased abundance of Nitric Oxide]; Capsaicin inhibits the reaction [IFNG protein results in increased expression of CIITA mRNA]; Capsaicin inhibits the reaction [IFNG protein results in increased expression of H2-AB1 mRNA]; Capsaicin inhibits the reaction [IFNG results in increased activity of STAT1 protein]; Capsaicin inhibits the reaction [IFNG results in increased expression of NOS2 protein]
[Capsaicin results in increased susceptibility to Glyoxal] which results in increased expression of IFNG mRNA; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IFNG protein]; Naproxen inhibits the reaction [Capsaicin results in decreased expression of IFNG protein]; Sumatriptan inhibits the reaction [Capsaicin results in decreased expression of IFNG protein]
CTD PMID:14530214 PMID:17306834 PMID:19825429 PMID:22150557 PMID:29496360 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
increases expression
ISO
EXP
CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]; CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 protein]; CALCA protein promotes the reaction [Capsaicin results in increased expression of IGF1 mRNA]; CALCA protein promotes the reaction [Capsaicin results in increased expression of IGF1 protein]; Isoflavones promotes the reaction [Capsaicin results in increased expression of IGF1 protein]
Capsaicin results in increased expression of IGF1 mRNA; Capsaicin results in increased expression of IGF1 protein
[Capsaicin co-treated with Isoflavones] results in increased expression of IGF1 protein; TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]
capsazepine inhibits the reaction [Capsaicin results in increased expression of IGF1 protein]
CTD PMID:17307377 PMID:17360009 PMID:17569567 PMID:17693108 PMID:19502719 More... NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression
multiple interactions
ISO Capsaicin results in increased expression of IGF1R mRNA
TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1R mRNA]
CTD PMID:21310942 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2 insulin-like growth factor 2 increases expression EXP Capsaicin results in increased expression of IGF2 mRNA CTD PMID:20349343 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
ISO
EXP
Capsaicin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]
Capsaicin results in increased expression of IL10 mRNA; Capsaicin results in increased expression of IL10 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL10 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL10 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL10 protein]
CTD PMID:15502055 PMID:18460982 PMID:19878665 PMID:22150557 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 decreases expression EXP Capsaicin results in decreased expression of IL11RA1 mRNA CTD PMID:16278290 NCBI chr 5:56,931,824...56,941,408
Ensembl chr 5:56,935,516...56,941,408
JBrowse link
G Il12b interleukin 12B decreases expression ISO Capsaicin results in decreased expression of IL12B mRNA CTD PMID:18533110 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il13 interleukin 13 multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL13 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL13 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL13 protein] CTD PMID:22150557 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
decreases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]; Naproxen inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]; Sumatriptan inhibits the reaction [Capsaicin results in decreased expression of IL1A protein] CTD PMID:22150557 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta decreases secretion
increases response to substance
multiple interactions
increases expression
affects expression
ISO
EXP
Capsaicin results in decreased secretion of IL1B protein
IL1B gene SNP results in increased susceptibility to Capsaicin
[Capsaicin results in increased susceptibility to Formaldehyde] which results in increased expression of IL1B mRNA; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of IL1B protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of IL1B protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of IL1B protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of IL1B protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of IL1B protein]
Capsaicin results in increased expression of IL1B mRNA; Capsaicin results in increased expression of IL1B protein
Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]
Capsaicin inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Capsaicin inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]; Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD PMID:12034025 PMID:15265675 PMID:18769453 PMID:19878665 PMID:22150557 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions EXP IL1RN protein inhibits the reaction [Nicotine results in increased activity of Capsaicin] CTD PMID:27180639 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il2 interleukin 2 decreases expression
multiple interactions
increases expression
ISO
EXP
Capsaicin results in decreased expression of IL2
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL2 protein]
CTD PMID:17306834 PMID:22150557 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il3 interleukin 3 multiple interactions
affects expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of IL3 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of IL3 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of IL3 protein] CTD PMID:22150557 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il4 interleukin 4 decreases expression
increases expression
multiple interactions
ISO
EXP
Capsaicin results in decreased expression of IL4
Capsaicin results in increased expression of IL4 mRNA; Capsaicin results in increased expression of IL4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL4 protein]
CTD PMID:17306834 PMID:22150557 PMID:29496360 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 decreases expression
multiple interactions
increases expression
ISO
EXP
Capsaicin results in decreased expression of IL5
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL5 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL5 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL5 protein]
Capsaicin results in increased expression of IL5 mRNA; Capsaicin results in increased expression of IL5 protein
CTD PMID:17306834 PMID:22150557 PMID:29496360 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
increases expression
decreases secretion
decreases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; 5-7-oxo-zeaenol inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; bisindolylmaleimide inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; capsazepine inhibits the reaction [Capsaicin results in increased expression of IL6 mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased secretion of IL6 protein]; Egtazic Acid inhibits the reaction [Capsaicin results in increased expression of IL6 mRNA]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; RTKI cpd affects the reaction [Capsaicin results in increased secretion of IL6 protein]; Ruthenium Red inhibits the reaction [Capsaicin results in increased expression of IL6 mRNA]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 mRNA]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 protein]
Capsaicin results in increased expression of IL6 mRNA; Capsaicin results in increased expression of IL6 protein
Capsaicin results in decreased secretion of IL6 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Capsaicin inhibits the reaction [IL6 protein results in increased expression of GFAP mRNA]; Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Ketotifen inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL6 protein]
Capsaicin results in decreased expression of IL6 protein
capsazepine inhibits the reaction [Capsaicin results in decreased secretion of IL6 protein]; troglitazone promotes the reaction [Capsaicin results in decreased secretion of IL6 protein]
Capsaicin results in decreased expression of IL6 mRNA; Capsaicin results in decreased expression of IL6 protein
CTD PMID:15265675 PMID:15502055 PMID:16173059 PMID:17306835 PMID:17505005 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer decreases expression EXP Capsaicin results in decreased expression of IL6ST protein CTD PMID:19285962 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
JBrowse link
G Il7 interleukin 7 decreases expression EXP Capsaicin results in decreased expression of IL7 mRNA CTD PMID:16278290 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Inhba inhibin subunit beta A increases expression
multiple interactions
EXP Capsaicin results in increased expression of INHBA protein
Naproxen inhibits the reaction [Capsaicin results in increased expression of INHBA protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of INHBA protein]
CTD PMID:22150557 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Ins2 insulin 2 multiple interactions EXP [INS protein co-treated with Capsaicin] promotes the reaction [Capsaicin results in increased uptake of cobaltous chloride] CTD PMID:14622148 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Irs1 insulin receptor substrate 1 increases expression ISO Capsaicin results in increased expression of IRS1 mRNA CTD PMID:19798065 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Itga5 integrin subunit alpha 5 increases expression EXP Capsaicin results in increased expression of ITGA5 mRNA CTD PMID:16278290 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO Capsaicin results in decreased phosphorylation of and results in decreased activity of JAK1 protein CTD PMID:17505005 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression
multiple interactions
ISO
EXP
Capsaicin results in decreased expression of JUN mRNA
Capsaicin results in increased expression of JUN mRNA
[Capsaicin results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; Capsaicin inhibits the reaction [EGF results in increased localization of JUN protein]
CTD PMID:1922926 PMID:9580328 PMID:17292493 PMID:19502594 PMID:21462327 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression EXP Capsaicin results in increased expression of JUND mRNA CTD PMID:16278290 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 increases expression EXP Capsaicin results in increased expression of KCNQ4 mRNA CTD PMID:16278290 NCBI chr 5:134,275,145...134,326,992
Ensembl chr 5:134,275,934...134,326,932
JBrowse link
G Kif11 kinesin family member 11 increases expression EXP Capsaicin results in increased expression of KIF11 mRNA CTD PMID:16278290 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Klf1 Kruppel like factor 1 increases expression ISO Capsaicin results in increased expression of KLF1 mRNA CTD PMID:17603282 NCBI chr19:23,250,627...23,253,802
Ensembl chr19:23,250,631...23,253,758
JBrowse link
G Klf4 Kruppel like factor 4 increases expression EXP Capsaicin results in increased expression of KLF4 mRNA CTD PMID:20349343 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klk6 kallikrein related-peptidase 6 increases expression EXP Capsaicin results in increased expression of KLK6 mRNA CTD PMID:20349343 NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121
JBrowse link
G Kng2 kininogen 2 multiple interactions
affects activity
increases response to substance
EXP
ISO
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [KNG1 protein results in increased susceptibility to Capsaicin]; 2-aminoethyl diphenylborinate inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Capsaicin inhibits the reaction [[KNG1 protein alternative form binds to and results in increased activity of BDKRB2 protein] which results in increased abundance of Inositol Phosphates]; Capsaicin promotes the reaction [Nicotine results in decreased activity of KNG1 protein alternative form]; HU 211 inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Indomethacin inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; U 73343 promotes the reaction [KNG1 protein results in increased susceptibility to Capsaicin]
KNG1 protein alternative form affects the reaction [P2RY2 protein affects the susceptibility to Capsaicin]
Capsaicin affects the activity of KNG1 protein
BDKRB2 affects the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]; KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]
CTD PMID:7807204 PMID:10490893 PMID:15363968 PMID:15750287 PMID:16696851 More... NCBI chr11:77,913,876...77,936,247 JBrowse link
G Lep leptin decreases expression
multiple interactions
increases expression
ISO
EXP
Capsaicin results in decreased expression of LEP protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of LEP protein]; Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of LEP mRNA]; Naproxen inhibits the reaction [Capsaicin results in increased expression of LEP protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of LEP protein]
Capsaicin results in increased expression of LEP mRNA; Capsaicin results in increased expression of LEP protein
CTD PMID:16278290 PMID:17295509 PMID:19798065 PMID:20359164 PMID:22150557 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lgals1 galectin 1 increases expression ISO Capsaicin results in increased expression of LGALS1 protein CTD PMID:18991268 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G Lrp1 LDL receptor related protein 1 multiple interactions
decreases response to substance
decreases expression
ISO 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; [Capsaicin results in decreased expression of LRP1 protein] which results in decreased uptake of Cholesterol; [Capsaicin results in decreased expression of LRP1 protein] which results in increased secretion of Cholesterol; APOE affects the reaction [Capsaicin results in decreased expression of LRP1 protein]; Cyclosporine inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; KT 5720 inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]
LRP1 results in decreased susceptibility to Capsaicin
CTD PMID:21908651 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 decreases expression EXP Capsaicin results in decreased expression of LTB4R2 mRNA CTD PMID:16278290 NCBI chr15:29,258,427...29,260,340
Ensembl chr15:29,259,240...29,260,316
JBrowse link
G Ltf lactotransferrin increases expression ISO Capsaicin results in increased expression of LTF protein CTD PMID:9537786 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Map2 microtubule-associated protein 2 increases expression ISO Capsaicin results in increased expression of MAP2 mRNA CTD PMID:18405923 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression ISO Capsaicin results in increased expression of MAP2K1 mRNA CTD PMID:19502594 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 multiple interactions ISO 5-7-oxo-zeaenol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAP3K7 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAP3K7 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAP3K7 protein] CTD PMID:22171160 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases activity
increases phosphorylation
multiple interactions
increases expression
increases localization
increases activity
ISO
EXP
Capsaicin results in decreased activity of MAPK1 protein
Capsaicin results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK1 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Genistein inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Lidocaine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; staurosporine aglycone inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; substance P (6-11), Tyr(6)-D-Phe(7)-D-His(9)- inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Xenon inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]; Capsaicin results in increased activity of and results in increased phosphorylation of MAPK1 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 5-7-oxo-zeaenol inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK1 protein]; Capsaicin results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; tricyclodecane-9-yl-xanthogenate inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]
Capsaicin results in increased expression of MAPK1 protein modified form
Capsaicin results in increased localization of MAPK1 protein modified form
CTD PMID:12196597 PMID:12478662 PMID:12941468 PMID:14530214 PMID:15385614 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK14 protein] CTD PMID:21745629 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases activity
increases phosphorylation
multiple interactions
increases expression
increases localization
increases activity
ISO
EXP
Capsaicin results in decreased activity of MAPK3 protein
Capsaicin results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK3 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Genistein inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Lidocaine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Ro 31-8425 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]]; Ro 31-8425 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Ro 31-8425 promotes the reaction [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]]; SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; staurosporine aglycone inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; substance P (6-11), Tyr(6)-D-Phe(7)-D-His(9)- inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Xenon inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK3 protein]; Capsaicin results in increased activity of and results in increased phosphorylation of MAPK3 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 5-7-oxo-zeaenol inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK3 protein]; Capsaicin results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; tricyclodecane-9-yl-xanthogenate inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]
Capsaicin results in increased expression of MAPK3 protein modified form
Capsaicin results in increased localization of MAPK3 protein modified form
CTD PMID:12196597 PMID:12478662 PMID:12941468 PMID:14530214 PMID:15385614 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 increases phosphorylation EXP Capsaicin results in increased phosphorylation of MAPK7 protein CTD PMID:17237256 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases activity
increases phosphorylation
ISO 5-7-oxo-zeaenol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; 5-7-oxo-zeaenol promotes the reaction [MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]]; [Capsaicin results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK8 protein]; Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; MAPK8 protein promotes the reaction [Capsaicin results in decreased degradation of TP53 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]
Capsaicin results in increased phosphorylation of MAPK8 protein
CTD PMID:9580328 PMID:12478662 PMID:17292493 PMID:20619260 PMID:21462327 More... NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases activity
increases phosphorylation
multiple interactions
ISO Capsaicin results in increased activity of MAPK9 protein
Capsaicin results in increased phosphorylation of MAPK9 protein
Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK9 protein]; Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]
CTD PMID:9580328 PMID:20619260 PMID:21462327 PMID:21745629 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression EXP Capsaicin results in increased expression of MARCKS mRNA CTD PMID:20349343 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Capsaicin results in increased expression of MCL1 mRNA CTD PMID:19502594 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mdh1 malate dehydrogenase 1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of MDH1 protein] CTD PMID:20359164 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression
decreases expression
multiple interactions
ISO Capsaicin results in increased expression of MDM2 mRNA
Capsaicin results in decreased expression of MDM2 protein
Capsaicin promotes the reaction [resveratrol results in decreased expression of MDM2 protein]; resveratrol promotes the reaction [Capsaicin results in decreased expression of MDM2 protein]; TP53 affects the reaction [Capsaicin results in decreased expression of MDM2 protein]
CTD PMID:19502594 PMID:19846903 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mif macrophage migration inhibitory factor increases expression
multiple interactions
EXP Capsaicin results in increased expression of MIF protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MIF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MIF protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MIF protein]
CTD PMID:22150557 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP Capsaicin inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MKI67 protein] CTD PMID:29155087 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression
ISO capsazepine inhibits the reaction [Capsaicin results in increased expression of MMP1 protein]
Capsaicin results in increased expression of MMP1 mRNA; Capsaicin results in increased expression of MMP1 protein
CTD PMID:17508023 PMID:21310942 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp12 matrix metallopeptidase 12 decreases expression ISO Capsaicin results in decreased expression of MMP12 mRNA; Capsaicin results in decreased expression of MMP12 protein CTD PMID:18441096 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp13 matrix metallopeptidase 13 decreases expression
multiple interactions
increases expression
EXP Capsaicin results in decreased expression of MMP13 mRNA
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MMP13 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MMP13 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MMP13 protein]
CTD PMID:16278290 PMID:22150557 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions ISO Capsaicin inhibits the reaction [EGF results in increased expression of MMP14] CTD PMID:21462327 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO
EXP
Capsaicin inhibits the reaction [EGF results in increased activity of MMP2 protein]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP2]
Capsaicin results in increased expression of MMP2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MMP2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MMP2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MMP2 protein]
CTD PMID:21462327 PMID:22150557 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO 4-aminobenzamide inhibits the reaction [Capsaicin results in increased activity of MMP9 protein]; Capsaicin inhibits the reaction [EGF results in increased activity of MMP9 protein]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP9]; Capsaicin results in increased expression of and results in increased activity of MMP9 protein; TRPV1 inhibits the reaction [Capsaicin results in increased expression of and results in increased activity of MMP9 protein]
Capsaicin results in increased expression of MMP9 mRNA
CTD PMID:21310942 PMID:21462327 PMID:22230393 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mobp myelin-associated oligodendrocyte basic protein increases expression EXP Capsaicin results in increased expression of MOBP mRNA CTD PMID:20349343 NCBI chr 8:119,869,504...119,899,605
Ensembl chr 8:119,869,626...119,899,563
JBrowse link
G Mog myelin oligodendrocyte glycoprotein increases expression EXP Capsaicin results in increased expression of MOG mRNA CTD PMID:20349343 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
JBrowse link
G Mpo myeloperoxidase affects activity
decreases expression
multiple interactions
EXP Capsaicin affects the activity of MPO protein
Capsaicin results in decreased expression of MPO protein
Capsaicin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Diquat results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Indomethacin results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Iodoacetamide results in increased activity of MPO protein]; Capsaicin promotes the reaction [Ethanol results in increased activity of MPO protein]; Indomethacin inhibits the reaction [Capsaicin affects the activity of MPO protein]
CTD PMID:10671773 PMID:12024109 PMID:12893632 PMID:15046732 PMID:15573930 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mrpl3 mitochondrial ribosomal protein L3 decreases expression EXP Capsaicin results in decreased expression of MRPL3 mRNA CTD PMID:16278290 NCBI chr 8:105,670,184...105,693,544
Ensembl chr 8:105,670,184...105,693,544
JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Capsaicin results in increased expression of MSMO1 mRNA CTD PMID:18533110 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 increases response to substance
multiple interactions
ISO ND1 gene mutant form results in increased susceptibility to Capsaicin
[ND1 gene mutant form results in increased susceptibility to Capsaicin] which results in increased activity of CASP3 protein
CTD PMID:29991444 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MTOR protein]; wortmannin inhibits the reaction [Capsaicin results in increased phosphorylation of MTOR protein]
Capsaicin results in decreased phosphorylation of MTOR protein
CTD PMID:19139269 PMID:22226932 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases secretion
multiple interactions
ISO Capsaicin results in increased secretion of MUC5AC protein
Capsaicin promotes the reaction [Citric Acid results in increased secretion of MUC5AC protein]
CTD PMID:22566028 NCBI chr 1:196,864,375...196,896,475 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming increases secretion ISO Capsaicin results in increased secretion of MUC5B protein CTD PMID:21981454 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250
JBrowse link
G Musk muscle associated receptor tyrosine kinase multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MUSK protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MUSK protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MUSK protein] CTD PMID:22150557 NCBI chr 5:73,058,427...73,169,696
Ensembl chr 5:73,058,121...73,171,932
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Capsaicin results in increased expression of MYC mRNA CTD PMID:9461043 PMID:19502594 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myl1 myosin, light chain 1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of MYL1 protein] CTD PMID:20359164 NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261
JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO Capsaicin results in decreased expression of MYL4 mRNA CTD PMID:33512557 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
JBrowse link
G Ncr1 natural cytotoxicity triggering receptor 1 increases expression EXP Capsaicin results in increased expression of NCR1 mRNA CTD PMID:16278290 NCBI chr 1:69,614,744...69,622,570 JBrowse link
G Ndufb4 NADH:ubiquinone oxidoreductase subunit B4 decreases expression EXP Capsaicin results in decreased expression of NDUFB4 mRNA CTD PMID:16278290 NCBI chr11:63,063,802...63,070,426
Ensembl chr11:63,063,795...63,070,425
JBrowse link
G Nectin1 nectin cell adhesion molecule 1 increases expression EXP Capsaicin results in increased expression of NECTIN1 mRNA CTD PMID:16278290 NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787
JBrowse link
G Nek2 NIMA-related kinase 2 increases expression ISO Capsaicin results in increased expression of NEK2 mRNA CTD PMID:33512557 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 increases localization EXP Capsaicin results in increased localization of NFATC4 protein CTD PMID:16849427 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Nfe2 nuclear factor, erythroid 2 increases expression ISO Capsaicin results in increased expression of NFE2 mRNA CTD PMID:17603282 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases localization
ISO Acetylcysteine inhibits the reaction [Capsaicin results in increased localization of NFE2L2 protein] CTD PMID:17979524 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects expression
multiple interactions
ISO Capsaicin affects the expression of NFKB1 mRNA
[NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]] which results in increased expression of DUSP1 protein; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]
CTD PMID:19502594 PMID:22171160 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases localization
increases phosphorylation
decreases degradation
ISO 5-7-oxo-zeaenol promotes the reaction [MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]]; Capsaicin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]
Capsaicin results in increased localization of NFKBIA protein
Capsaicin results in decreased degradation of NFKBIA protein
CTD PMID:12214859 PMID:16540674 PMID:22171160 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngf nerve growth factor multiple interactions
increases response to substance
increases expression
decreases expression
ISO
EXP
NTRK1 promotes the reaction [NGF protein results in increased susceptibility to Capsaicin]; NTRK1 protein mutant form affects the reaction [NGF protein results in increased susceptibility to Capsaicin]
Capsaicin results in increased expression of NGF protein
Capsaicin results in decreased expression of NGF protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [U 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; [Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGF protein]; bisindolylmaleimide I inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; epothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]; Ketotifen inhibits the reaction [Capsaicin results in increased expression of NGF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of NGF protein]; NGF protein promotes the reaction [Capsaicin results in increased expression of CALCA protein]; NGF protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Promethazine inhibits the reaction [Capsaicin results in increased expression of NGF protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of NGF protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of NGF protein]; staurosporine aglycone inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of NGF protein]; U 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; U 0126 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]
NGF protein results in increased susceptibility to Capsaicin; NGF results in increased susceptibility to Capsaicin
Capsaicin results in decreased expression of NGF mRNA
bisindolylmaleimide I inhibits the reaction [NGF results in increased susceptibility to Capsaicin]; Capsaicin inhibits the reaction [CCK protein alternative form results in decreased expression of NGF mRNA]; Capsaicin promotes the reaction [CCK protein alternative form results in increased expression of NGF protein]; KN 62 inhibits the reaction [NGF results in increased susceptibility to Capsaicin]; PIK3R1 gene mutant form inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; Staurosporine inhibits the reaction [NGF results in increased susceptibility to Capsaicin]; wortmannin inhibits the reaction [NGF results in increased susceptibility to Capsaicin]
CTD PMID:9259450 PMID:10683199 PMID:11166474 PMID:12815188 PMID:15265675 More... NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ngfr nerve growth factor receptor increases expression
multiple interactions
decreases expression
EXP Capsaicin results in increased expression of NGFR protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGFR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of NGFR protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of NGFR protein]
Capsaicin results in decreased expression of NGFR mRNA
CTD PMID:8971780 PMID:22150557 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression ISO Capsaicin results in increased expression of NME2 mRNA CTD PMID:21310942 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression
multiple interactions
EXP
ISO
Capsaicin results in increased expression of NOS1 mRNA; Capsaicin results in increased expression of NOS1 protein
TP53 affects the reaction [Capsaicin results in increased expression of NOS1 protein]
CTD PMID:7477891 PMID:10880996 PMID:11576744 PMID:19846903 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO
EXP
Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]; resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]]
Capsaicin inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]
Capsaicin results in increased expression of NOS2; Capsaicin results in increased expression of NOS2 mRNA; Capsaicin results in increased expression of NOS2 protein
Capsaicin inhibits the reaction [[IFNG protein results in increased abundance of Nitric Oxide] which results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [[Lipopolysaccharides results in increased abundance of Nitric Oxide] which results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [IFNG results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD PMID:10671773 PMID:11576744 PMID:14530214 PMID:15681035 PMID:19846903 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases expression
increases expression
ISO
EXP
Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]; resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]]; TP53 affects the reaction [Capsaicin results in increased expression of NOS3 protein]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]]
Capsaicin results in decreased expression of NOS3 mRNA
CTD PMID:16278290 PMID:18037908 PMID:19846903 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox3 NADPH oxidase 3 multiple interactions
increases expression
EXP
ISO
NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 protein]
NOX3 mutant form inhibits the reaction [Capsaicin results in increased abundance of Reactive Oxygen Species]
Capsaicin results in increased expression of NOX3 mRNA; Capsaicin results in increased expression of NOX3 protein
CTD PMID:20712533 NCBI chr 1:44,238,012...44,302,851
Ensembl chr 1:44,236,992...44,302,851
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 increases expression ISO Capsaicin results in increased expression of NPC1 mRNA CTD PMID:18533110 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049
JBrowse link
G Npy neuropeptide Y multiple interactions EXP Capsaicin inhibits the reaction [NPY protein affects the susceptibility to Potassium] CTD PMID:18055875 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions
increases response to substance
EXP neuropeptide Y, Leu(31)-Pro(34)- inhibits the reaction [NPY1R protein results in increased susceptibility to Capsaicin] CTD PMID:16714086 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
decreases expression
ISO
EXP
Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of NQO1 protein]
Capsaicin results in increased expression of NQO1 mRNA
Capsaicin results in decreased expression of NQO1 protein
CTD PMID:10880996 PMID:17979524 PMID:19449198 PMID:33512557 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of NQO2 protein] CTD PMID:20359164 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link
G Nrp1 neuropilin 1 multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NRP1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of NRP1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of NRP1 protein] CTD PMID:22150557 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 multiple interactions
decreases expression
ISO
EXP
NTRK1 promotes the reaction [NGF protein results in increased susceptibility to Capsaicin]; NTRK1 protein mutant form affects the reaction [NGF protein results in increased susceptibility to Capsaicin]
Capsaicin results in decreased expression of NTRK1 mRNA
CTD PMID:8971780 PMID:9259450 PMID:17324588 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions ISO Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased expression of OGDH] CTD PMID:18023135 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Olig1 oligodendrocyte transcription factor 1 increases expression EXP Capsaicin results in increased expression of OLIG1 mRNA CTD PMID:20349343 NCBI chr11:30,514,379...30,516,521
Ensembl chr11:30,514,379...30,516,521
JBrowse link
G Olr1271 olfactory receptor 1271 increases expression EXP Capsaicin results in increased expression of OLR1271 mRNA CTD PMID:16278290 NCBI chr 8:39,127,409...39,131,889
Ensembl chr 8:39,127,352...39,131,900
JBrowse link
G Olr1434 olfactory receptor 1434 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of OLR1434 protein] CTD PMID:20359164 NCBI chr10:43,072,884...43,073,804
Ensembl chr10:43,072,884...43,073,804
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions EXP OPRL1 protein promotes the reaction [nociceptin (1-13) amide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]] CTD PMID:17640294 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO Capsaicin inhibits the reaction [carfentanil binds to OPRM1 protein] CTD PMID:12406535 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G P22k15 cystatin related protein 2 decreases expression EXP Capsaicin results in decreased expression of P22K15 mRNA CTD PMID:16278290 NCBI chr 3:136,960,300...136,967,358
Ensembl chr 3:136,960,303...136,967,358
JBrowse link
G P2ry2 purinergic receptor P2Y2 affects response to substance
multiple interactions
ISO P2RY2 protein affects the susceptibility to Capsaicin
KNG1 protein alternative form affects the reaction [P2RY2 protein affects the susceptibility to Capsaicin]
CTD PMID:18343036 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
increases expression
increases ADP-ribosylation
multiple interactions
ISO Capsaicin results in increased cleavage of PARP1 protein
Capsaicin results in increased expression of PARP1 protein
Capsaicin results in increased ADP-ribosylation of PARP1 protein modified form
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; 3-aminobenzamide inhibits the reaction [Capsaicin results in increased ADP-ribosylation of PARP1 protein modified form]; 3-aminobenzamide promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; 3-aminobenzamide promotes the reaction [Capsaicin results in increased expression of PARP1 protein]; Caffeine promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of PARP1 protein]; Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein; pifithrin promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]
CTD PMID:17295509 PMID:17505005 PMID:19855437 PMID:22200406 PMID:22226932 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pclaf PCNA clamp associated factor increases expression EXP Capsaicin results in increased expression of PCLAF mRNA CTD PMID:20349343 NCBI chr 8:66,420,673...66,432,568
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pcolce procollagen C-endopeptidase enhancer increases expression EXP Capsaicin results in increased expression of PCOLCE mRNA CTD PMID:16278290 NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 decreases expression EXP Capsaicin results in decreased expression of PCSK5 mRNA CTD PMID:16278290 NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600
JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression ISO Capsaicin results in decreased expression of PCTP mRNA CTD PMID:18533110 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pde2a phosphodiesterase 2A decreases expression EXP Capsaicin results in decreased expression of PDE2A mRNA CTD PMID:20349343 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
JBrowse link
G Pdgfa platelet derived growth factor subunit A increases expression
multiple interactions
EXP Capsaicin results in increased expression of PDGFA protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PDGFA protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PDGFA protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of PDGFA protein]
CTD PMID:22150557 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 decreases expression EXP Capsaicin results in decreased expression of PDX1 mRNA CTD PMID:16278290 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Pdyn prodynorphin increases expression
multiple interactions
EXP Capsaicin results in increased expression of PDYN mRNA; Capsaicin results in increased expression of PDYN protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of PDYN protein]
CTD PMID:15385614 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Pdzd2 PDZ domain containing 2 increases expression EXP Capsaicin results in increased expression of PDZD2 mRNA CTD PMID:16278290 NCBI chr 2:61,384,614...61,770,516
Ensembl chr 2:61,386,381...61,770,524
JBrowse link
G Per2 period circadian regulator 2 increases expression EXP Capsaicin results in increased expression of PER2 mRNA CTD PMID:24746025 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression
decreases expression
ISO
EXP
Capsaicin results in increased expression of PGM1 mRNA; Capsaicin results in increased expression of PGM1 protein
Capsaicin results in decreased expression of PGM1 mRNA
CTD PMID:19891501 PMID:20349343 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
JBrowse link
G Phb2 prohibitin 2 multiple interactions ISO Capsaicin binds to and results in increased localization of PHB2 protein CTD PMID:19116139 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272
JBrowse link
G Phox2a paired-like homeobox 2a increases expression EXP Capsaicin results in increased expression of PHOX2A mRNA CTD PMID:16278290 NCBI chr 1:156,178,754...156,183,118
Ensembl chr 1:156,178,754...156,183,118
JBrowse link
G Phykpl 5-phosphohydroxy-L-lysine phospho-lyase increases expression EXP Capsaicin results in increased expression of PHYKPL mRNA CTD PMID:20349343 NCBI chr10:35,839,965...35,863,631
Ensembl chr10:35,839,983...35,859,508
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO PIK3R1 gene mutant form inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin] CTD PMID:17324588 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pla2g15 phospholipase A2, group XV decreases expression EXP Capsaicin results in decreased expression of PLA2G15 mRNA CTD PMID:20349343 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions
increases phosphorylation
ISO SB 203580 inhibits the reaction [Capsaicin results in increased phosphorylation of PLA2G4A protein] CTD PMID:19959817 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Capsaicin results in increased expression of PLAU mRNA CTD PMID:21310942 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression ISO Capsaicin results in increased expression of PLAUR mRNA CTD PMID:21310942 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Plcb3 phospholipase C beta 3 decreases expression EXP Capsaicin results in decreased expression of PLCB3 mRNA CTD PMID:20349343 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
JBrowse link
G Plin2 perilipin 2 affects expression
multiple interactions
EXP Capsaicin affects the expression of PLIN2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of PLIN2 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of PLIN2 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of PLIN2 protein]
CTD PMID:22150557 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Plp1 proteolipid protein 1 increases expression EXP Capsaicin results in increased expression of PLP1 mRNA CTD PMID:20349343 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032
JBrowse link
G Pnisr PNN interacting serine and arginine rich protein increases expression EXP Capsaicin results in increased expression of PNISR mRNA CTD PMID:20349343 NCBI chr 5:35,395,965...35,422,852
Ensembl chr 5:35,395,965...35,422,844
JBrowse link
G Polb DNA polymerase beta decreases expression EXP Capsaicin results in decreased expression of POLB mRNA CTD PMID:16278290 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Polr2f RNA polymerase II, I and III subunit F increases expression EXP Capsaicin results in increased expression of POLR2F mRNA CTD PMID:16278290 NCBI chr 7:110,712,528...110,724,234
Ensembl chr 7:110,712,572...110,724,234
JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases secretion
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of POMC protein]; Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein]; Capsaicin inhibits the reaction [[Morphine co-treated with Naloxone] results in increased secretion of POMC protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; CP 96345 inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; Lidocaine inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of POMC protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of POMC protein] CTD PMID:2846107 PMID:8925284 PMID:22150557 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO Capsaicin inhibits the reaction [Benzo(a)pyrene results in increased expression of POR protein] CTD PMID:19449198 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
increases expression
ISO Capsaicin results in decreased expression of PPARA mRNA
Capsaicin results in increased expression of PPARA mRNA
CTD PMID:18769453 PMID:19798065 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO Capsaicin results in decreased expression of PPARD mRNA CTD PMID:18769453 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases activity
decreases expression
ISO
EXP
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Capsaicin results in increased activity of PPARG protein]
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of PPARG mRNA]
Capsaicin results in decreased expression of PPARG protein
Capsaicin results in decreased expression of PPARG mRNA
CTD PMID:15383218 PMID:17295509 PMID:18769453 PMID:20359164 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
multiple interactions
ISO
EXP
Capsaicin results in increased expression of PPARGC1A mRNA
Capsaicin promotes the reaction [Dietary Fats results in increased expression of PPARGC1A mRNA]
CTD PMID:19798065 PMID:20359164 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO Capsaicin inhibits the reaction [Colforsin results in increased phosphorylation of PPP1R12A protein] CTD PMID:21474433 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions EXP PPP3CA protein affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]] CTD PMID:17590514 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit increases expression EXP Capsaicin results in increased expression of PPP5C mRNA CTD PMID:16278290 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of PRDX1 protein] CTD PMID:20359164 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prdx6 peroxiredoxin 6 increases expression ISO Capsaicin results in increased expression of PRDX6 protein CTD PMID:18991268 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions
increases expression
ISO
EXP
[Genistein co-treated with Capsaicin] results in increased activity of PRKAA1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]
CTD PMID:19723084 PMID:22150557 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases phosphorylation ISO Capsaicin results in increased phosphorylation of PRKACA protein CTD PMID:21908651 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkca protein kinase C, alpha increases expression
multiple interactions
EXP
ISO
Capsaicin results in increased expression of PRKCA mRNA; Capsaicin results in increased expression of PRKCA protein
bisindolylmaleimide inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]
chelerythrine inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]
CTD PMID:18752301 PMID:21474332 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcd protein kinase C, delta increases expression
multiple interactions
ISO Capsaicin results in increased expression of PRKCD protein
[NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]] which results in increased expression of DUSP1 protein; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]
CTD PMID:22171160 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] CTD PMID:16793902 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkcz protein kinase C, zeta increases response to substance ISO PRKCZ protein alternative form results in increased susceptibility to Capsaicin CTD PMID:27899695 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Prkd1 protein kinase D1 multiple interactions ISO
EXP
PRKD1 promotes the reaction [Capsaicin results in increased uptake of Calcium]
PRKD1 mutant form inhibits the reaction [Capsaicin results in increased uptake of Calcium]
CTD PMID:15471852 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions
increases phosphorylation
ISO 3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of PRKDC protein]; ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of PRKDC protein]; Capsaicin results in increased phosphorylation of and results in increased activity of PRKDC protein; pifithrin inhibits the reaction [Capsaicin results in increased phosphorylation of PRKDC protein] CTD PMID:22226932 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Prlr prolactin receptor increases expression
multiple interactions
EXP Capsaicin results in increased expression of PRLR protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PRLR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PRLR protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of PRLR protein]
CTD PMID:22150557 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
JBrowse link
G Prok1 prokineticin 1 multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PROK1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PROK1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of PROK1 protein] CTD PMID:22150557 NCBI chr 2:194,853,991...194,859,250
Ensembl chr 2:194,853,991...194,859,250
JBrowse link
G Prok2 prokineticin 2 increases response to substance ISO PROK2 protein results in increased susceptibility to Capsaicin CTD PMID:17107623 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
JBrowse link
G Prokr1 prokineticin receptor 1 multiple interactions
increases response to substance
ISO PROKR1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]
PROKR1 protein results in increased susceptibility to Capsaicin
CTD PMID:16793879 NCBI chr 4:120,022,301...120,033,379
Ensembl chr 4:120,021,747...120,033,379
JBrowse link
G Prokr2 prokineticin receptor 2 decreases expression EXP Capsaicin results in decreased expression of PROKR2 mRNA CTD PMID:16278290 NCBI chr 3:119,624,738...119,639,442
Ensembl chr 3:119,627,601...119,635,718
JBrowse link
G Ptgir prostaglandin I2 receptor increases response to substance ISO PTGIR results in increased susceptibility to Capsaicin CTD PMID:15985616 NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
decreases expression
ISO
EXP
Capsaicin promotes the reaction [Genistein results in decreased expression of PTGS2 protein]
Capsaicin results in increased expression of PTGS2 mRNA; Capsaicin results in increased expression of PTGS2 protein
[Genistein co-treated with Capsaicin] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Botulinum Toxins, Type A inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein; Capsaicin inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; EGFR gene mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]
Capsaicin results in decreased expression of PTGS2 mRNA
Capsaicin results in decreased expression of PTGS2 protein
CTD PMID:11125845 PMID:14530214 PMID:17141941 PMID:17719033 PMID:19723084 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO Capsaicin inhibits the reaction [EGF results in increased phosphorylation of PTK2 protein] CTD PMID:21462327 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ranbp3l RAN binding protein 3-like increases expression EXP Capsaicin results in increased expression of RANBP3L mRNA CTD PMID:20349343 NCBI chr 2:58,057,887...58,113,158
Ensembl chr 2:58,058,263...58,113,172
JBrowse link
G Rarres2 retinoic acid receptor responder 2 multiple interactions ISO RARRES2 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] CTD PMID:20383154 NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rbm5 RNA binding motif protein 5 increases expression EXP Capsaicin results in increased expression of RBM5 mRNA CTD PMID:20349343 NCBI chr 8:108,420,220...108,449,481
Ensembl chr 8:108,420,222...108,449,430
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases activity
decreases localization
ISO Capsaicin results in decreased activity of RELA protein
Capsaicin results in decreased localization of RELA protein
CTD PMID:12214859 PMID:16540674 PMID:17719033 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Retn resistin increases expression
multiple interactions
EXP Capsaicin results in increased expression of RETN protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of RETN protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of RETN protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of RETN protein]
CTD PMID:22150557 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Retnlb resistin like beta multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of RETNLB protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of RETNLB protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of RETNLB protein] CTD PMID:22150557 NCBI chr11:51,983,482...51,985,368
Ensembl chr11:51,983,483...51,985,368
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 increases expression ISO Capsaicin results in increased expression of RIPK2 mRNA CTD PMID:19502594 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 increases expression ISO Capsaicin results in increased expression of RPS6KA3 protein CTD PMID:18991268 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:35,517,306...35,623,207
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation ISO Capsaicin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22226932 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G RT1-Bb RT1 class II, locus Bb multiple interactions ISO Capsaicin inhibits the reaction [IFNG protein results in increased expression of H2-AB1 mRNA] CTD PMID:19825429 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO Capsaicin results in decreased expression of RXRA mRNA CTD PMID:18769453 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrb retinoid X receptor beta decreases expression ISO Capsaicin results in decreased expression of RXRB mRNA CTD PMID:18769453 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO Capsaicin results in increased expression of S100A4 mRNA CTD PMID:21310942 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100b S100 calcium binding protein B increases expression EXP Capsaicin results in increased expression of S100B protein CTD PMID:17635592 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G S100g S100 calcium binding protein G increases expression EXP Capsaicin results in increased expression of S100G mRNA CTD PMID:16278290 NCBI chr  X:31,705,853...31,708,422
Ensembl chr  X:31,705,866...31,708,433
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions
increases response to substance
ISO SCN10A protein affects the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]
SCN10A results in increased susceptibility to Capsaicin
CTD PMID:12351708 PMID:18845912 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
JBrowse link
G Scp2 sterol carrier protein 2 decreases expression ISO Capsaicin results in decreased expression of SCP2 mRNA CTD PMID:18533110 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Sele selectin E increases expression
multiple interactions
EXP Capsaicin results in increased expression of SELE protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SELE protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of SELE protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of SELE protein]
CTD PMID:22150557 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sell selectin L increases expression
multiple interactions
EXP Capsaicin results in increased expression of SELL protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SELL protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of SELL protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of SELL protein]
CTD PMID:22150557 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Senp5 SUMO specific peptidase 5 decreases expression EXP Capsaicin results in decreased expression of SENP5 mRNA CTD PMID:20349343 NCBI chr11:68,784,699...68,819,569
Ensembl chr11:68,784,957...68,819,562
JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Capsaicin results in decreased expression of SERPINE1 mRNA CTD PMID:21310942 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sfpq splicing factor proline and glutamine rich increases expression EXP Capsaicin results in increased expression of SFPQ mRNA CTD PMID:20349343 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sh3bp5 SH3-domain binding protein 5 decreases expression EXP Capsaicin results in decreased expression of SH3BP5 mRNA CTD PMID:16278290 NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975
JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 increases expression EXP Capsaicin results in increased expression of SH3KBP1 mRNA CTD PMID:16278290 NCBI chr  X:34,877,862...35,223,013
Ensembl chr  X:34,877,866...35,222,747
JBrowse link
G Slc12a1 solute carrier family 12 member 1 multiple interactions
increases expression
EXP [Capsaicin co-treated with Sodium Chloride, Dietary] results in increased expression of SLC12A1 mRNA
Capsaicin results in increased expression of SLC12A1 mRNA
CTD PMID:17414671 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc12a2 solute carrier family 12 member 2 affects response to substance ISO SLC12A2 affects the susceptibility to Capsaicin CTD PMID:15135928 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Slc16a10 solute carrier family 16 member 10 decreases expression EXP Capsaicin results in decreased expression of SLC16A10 mRNA CTD PMID:16278290 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Capsaicin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO Capsaicin results in increased expression of SLC2A4 mRNA CTD PMID:19798065 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc37a1 solute carrier family 37 member 1 decreases expression EXP Capsaicin results in decreased expression of SLC37A1 mRNA CTD PMID:20349343 NCBI chr20:9,360,501...9,433,895
Ensembl chr20:9,378,836...9,433,892
JBrowse link
G Slit1 slit guidance ligand 1 increases expression EXP Capsaicin results in increased expression of SLIT1 mRNA CTD PMID:16278290 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
decreases response to substance
multiple interactions
ISO Capsaicin results in increased expression of SOD2 protein modified form
SOD2 results in decreased susceptibility to Capsaicin
phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in decreased activity of SOD2 protein]; phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in increased expression of SOD2 protein modified form]; tempol inhibits the reaction [Capsaicin results in decreased activity of SOD2 protein]; tempol inhibits the reaction [Capsaicin results in increased expression of SOD2 protein modified form]
CTD PMID:19129394 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sostdc1 sclerostin domain containing 1 increases expression EXP Capsaicin results in increased expression of SOSTDC1 mRNA CTD PMID:20349343 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions
increases localization
ISO Capsaicin promotes the reaction [SP1 protein binds to TNFSF10 promoter]
Capsaicin results in increased localization of SP1 protein
CTD PMID:22200406 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Spi1 Spi-1 proto-oncogene increases expression ISO Capsaicin results in increased expression of SPI1 mRNA CTD PMID:17603282 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SPP1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of SPP1 protein]; Sumatriptan promotes the reaction [Capsaicin results in increased expression of SPP1 protein] CTD PMID:22150557 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases activity
ISO
EXP
Capsaicin results in decreased phosphorylation of and results in decreased activity of SRC protein
AG 1879 inhibits the reaction [Capsaicin results in increased activity of SRC protein]
SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]
CTD PMID:17505005 PMID:20660715 PMID:21340460 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Sst somatostatin multiple interactions
increases secretion
decreases expression
increases expression
EXP
ISO
AMN protein inhibits the reaction [Capsaicin results in increased expression of SST protein]
Capsaicin results in increased secretion of SST protein
Capsaicin results in decreased expression of SST mRNA
CTD PMID:8093704 PMID:8093880 PMID:9932722 PMID:16938409 PMID:19296048 More... NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression
multiple interactions
increases response to substance
EXP
ISO
Capsaicin results in increased expression of STAT1 mRNA; Capsaicin results in increased expression of STAT1 protein
Capsaicin inhibits the reaction [IFNG results in increased activity of STAT1 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of STAT1 protein
STAT1 results in increased susceptibility to Capsaicin
Capsaicin results in increased phosphorylation of and results in increased activity of STAT1 protein; CYBB mutant form inhibits the reaction [Capsaicin results in increased expression of STAT1 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]
CTD PMID:14530214 PMID:20712533 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases phosphorylation
affects localization
ISO
EXP
Bortezomib promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein; pervanadate inhibits the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Thalidomide promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]
Capsaicin results in increased phosphorylation of STAT3 protein
Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of STAT3 protein]
Capsaicin affects the localization of STAT3 protein
CTD PMID:16788306 PMID:17505005 PMID:19285962 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Steap3 STEAP3 metalloreductase multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of STEAP3 protein] CTD PMID:20359164 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519
JBrowse link
G Sumo4 small ubiquitin-like modifier 4 increases expression ISO Capsaicin results in increased expression of SUMO4 protein CTD PMID:18991268 NCBI chr 5:15,099,322...15,099,913 JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase decreases expression EXP Capsaicin results in decreased expression of SUV39H1 mRNA CTD PMID:16278290 NCBI chr  X:141,793,695...141,795,558 JBrowse link
G Syn2 synapsin II increases response to substance ISO SYN2 results in increased susceptibility to Capsaicin CTD PMID:18701217 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 affects response to substance ISO SYNGAP1 affects the susceptibility to Capsaicin CTD PMID:21525372 NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672
JBrowse link
G Syt7 synaptotagmin 7 increases expression EXP Capsaicin results in increased expression of SYT7 mRNA CTD PMID:16278290 NCBI chr 1:207,031,369...207,093,787
Ensembl chr 1:207,031,592...207,089,026
JBrowse link
G Tac1 tachykinin, precursor 1 affects expression
decreases activity
decreases expression
decreases secretion
increases secretion
increases expression
multiple interactions
ISO
EXP
Capsaicin affects the expression of TAC1 protein
TAC1 protein results in decreased activity of Capsaicin
Capsaicin results in decreased expression of TAC1 mRNA; Capsaicin results in decreased expression of TAC1 protein
Capsaicin results in decreased secretion of TAC1 protein
Capsaicin results in increased secretion of TAC1 protein; Capsaicin results in increased secretion of TAC1 protein alternative form
Capsaicin results in increased expression of TAC1 mRNA; Capsaicin results in increased expression of TAC1 protein
[Capsaicin co-treated with CCK protein alternative form] results in increased expression of TAC1 protein; Capsaicin inhibits the reaction [sodium arsenite results in increased secretion of TAC1 protein]; SCN10A protein affects the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]; TAC1 protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; 2-aminoethyl diphenylborinate inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; AMN protein inhibits the reaction [Capsaicin results in increased expression of TAC1 protein]; bisindolylmaleimide I inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Capsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of TAC1 mRNA]; Capsaicin inhibits the reaction [Potassium results in increased secretion of TAC1 protein modified form]; Capsaicin results in increased expression of and results in increased secretion of TAC1 protein; capsazepine inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]; capsazepine inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; cochinchinenin inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]; Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; CP 96345 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; dragon's blood inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]; Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Gabapentin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; GAL protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]; Go 6976 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; HU 211 inhibits the reaction [Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; HU 211 inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Iloprost promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Indomethacin inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Indomethacin inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Morphine promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; NGF protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Pregabalin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Pregabalin inhibits the reaction [Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; pyrazolanthrone promotes the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; SB 203580 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; U 0126 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]
Capsaicin results in increased secretion of TAC1 protein; Capsaicin results in increased secretion of TAC1 protein alternative form; Capsaicin results in increased secretion of TAC1 protein modified form
CTD PMID:2325850 PMID:2480171 PMID:3412491 PMID:6205719 PMID:7473211 More... NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tac3 tachykinin precursor 3 decreases expression EXP Capsaicin results in decreased expression of TAC2 mRNA CTD PMID:16278290 NCBI chr 7:63,562,552...63,569,170
Ensembl chr 7:63,562,552...63,569,170
JBrowse link
G Tacr1 tachykinin receptor 1 decreases expression
increases expression
multiple interactions
affects expression
increases response to substance
ISO
EXP
Capsaicin results in decreased expression of TACR1 mRNA; Capsaicin results in decreased expression of TACR1 protein
Capsaicin results in increased expression of TACR1 protein
Capsaicin affects the reaction [Vehicle Emissions affects the expression of TACR1 mRNA]; Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TACR1 mRNA]; Capsaicin promotes the reaction [Vehicle Emissions results in increased expression of TACR1 protein]
Capsaicin affects the expression of TACR1 mRNA
TACR1 results in increased susceptibility to Capsaicin
CTD PMID:10360863 PMID:11166975 PMID:13680092 PMID:18441096 PMID:19399481 More... NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
G Tacr2 tachykinin receptor 2 increases response to substance
multiple interactions
decreases expression
ISO
EXP
TACR2 gene polymorphism results in increased susceptibility to Capsaicin
Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TACR2 mRNA]
Capsaicin results in decreased expression of TACR2 mRNA
CTD PMID:16278290 PMID:16893949 PMID:19399481 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446
JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor increases expression
multiple interactions
EXP Capsaicin results in increased expression of TAL1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TAL1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TAL1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TAL1 protein]
CTD PMID:22150557 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976
JBrowse link
G Tek TEK receptor tyrosine kinase increases expression
multiple interactions
EXP
ISO
Capsaicin results in increased expression of TEK protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TEK protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TEK protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TEK protein]
Capsaicin results in increased expression of TEK mRNA
CTD PMID:21310942 PMID:22150557 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tgfa transforming growth factor alpha increases expression EXP Capsaicin results in increased expression of TGFA mRNA; Capsaicin results in increased expression of TGFA protein CTD PMID:11989832 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
increases expression
multiple interactions
ISO
EXP
Capsaicin results in decreased expression of TGFB1 mRNA
Capsaicin results in increased expression of TGFB1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TGFB1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TGFB1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TGFB1 protein]
CTD PMID:18533110 PMID:22150557 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression
multiple interactions
EXP Capsaicin results in increased expression of TGFB2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TGFB2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TGFB2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TGFB2 protein]
CTD PMID:22150557 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 multiple interactions
increases expression
EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TGFB3 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TGFB3 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TGFB3 protein] CTD PMID:22150557 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Thop1 thimet oligopeptidase 1 increases expression EXP Capsaicin results in increased expression of THOP1 mRNA CTD PMID:16278290 NCBI chr 7:8,632,911...8,645,339
Ensembl chr 7:8,632,916...8,645,275
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions
ISO
EXP
Capsaicin results in increased expression of TIMP1 mRNA
Capsaicin results in increased expression of TIMP1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]
CTD PMID:21310942 PMID:22150557 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression
multiple interactions
EXP Capsaicin results in increased expression of TIMP2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TIMP2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP2 protein]
CTD PMID:22150557 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 increases expression
multiple interactions
ISO
EXP
Capsaicin results in increased expression of TIMP3 mRNA
Capsaicin results in increased expression of TIMP3 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP3 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TIMP3 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP3 protein]
CTD PMID:21310942 PMID:22150557 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Tlr4 toll-like receptor 4 increases expression
multiple interactions
EXP Capsaicin results in increased expression of TLR4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]
CTD PMID:22150557 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 decreases expression ISO Capsaicin results in decreased expression of TM7SF2 mRNA CTD PMID:18533110 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
JBrowse link
G Tmem37 transmembrane protein 37 increases expression EXP Capsaicin results in increased expression of TMEM37 mRNA CTD PMID:16278290 NCBI chr13:31,184,322...31,191,477
Ensembl chr13:31,171,355...31,191,077
JBrowse link
G Tnc tenascin C decreases expression ISO Capsaicin results in decreased expression of TNC mRNA CTD PMID:33512557 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnf tumor necrosis factor decreases secretion
increases expression
decreases expression
multiple interactions
increases secretion
increases response to substance
affects response to substance
ISO
EXP
Capsaicin results in decreased secretion of TNF protein
Capsaicin results in increased expression of TNF mRNA; Capsaicin results in increased expression of TNF protein
Capsaicin results in decreased expression of TNF mRNA; Capsaicin results in decreased expression of TNF protein
[Capsaicin results in increased susceptibility to Formaldehyde] which results in increased expression of TNF mRNA; [Capsaicin results in increased susceptibility to Glyoxal] which results in increased expression of TNF mRNA; [Lipopolysaccharides co-treated with Capsaicin] results in increased expression of TNF protein; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of TNF mRNA]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Capsaicin inhibits the reaction [monophosphoryl lipid A results in decreased expression of TNF protein]; Capsaicin inhibits the reaction [Nitroglycerin results in decreased expression of TNF protein]; capsazepine inhibits the reaction [Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Ketotifen inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TNF protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of TNF protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of TNF protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TNF protein]
Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]
Capsaicin results in increased secretion of TNF protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased secretion of TNF protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased secretion of TNF protein]; bisindolylmaleimide inhibits the reaction [Capsaicin results in increased secretion of TNF protein]; CALCA protein alternative form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; Capsaicin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Capsaicin inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; Capsaicin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA]; Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of TNF protein]
TNF protein results in increased susceptibility to Capsaicin
TNF protein affects the susceptibility to Capsaicin
CTD PMID:11408036 PMID:11744139 PMID:12024109 PMID:12034025 PMID:15265675 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO Capsaicin results in increased expression of TNFRSF10A mRNA; Capsaicin results in increased expression of TNFRSF10A protein CTD PMID:19502594 PMID:19846903 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 affects expression
multiple interactions
EXP Capsaicin affects the expression of TNFRSF19 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of TNFRSF19 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of TNFRSF19 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of TNFRSF19 protein]
CTD PMID:22150557 NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression
multiple interactions
ISO Capsaicin results in increased expression of TNFRSF1A mRNA
capsazepine inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]; phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]
CTD PMID:19531269 PMID:21310942 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO Capsaicin results in increased expression of TNFRSF25 mRNA CTD PMID:19502594 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions
increases expression
increases response to substance
increases activity
ISO
EXP
[Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP2 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP6 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP7 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP8 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP9 protein; BIRC5 results in decreased activity of [Capsaicin co-treated with TNFSF10 protein]; Capsaicin promotes the reaction [SP1 protein binds to TNFSF10 promoter]; Capsaicin promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP8 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP9 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of BID protein]; Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of PARP1 protein]; Egtazic Acid inhibits the reaction [Capsaicin results in increased expression of TNFSF10 mRNA]; staurosporine aglycone inhibits the reaction [Capsaicin results in increased expression of TNFSF10 mRNA]; TNFRSF10B mutant form inhibits the reaction [Capsaicin results in increased susceptibility to TNFSF10 protein]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TNFSF10 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TNFSF10 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TNFSF10 protein]
Capsaicin results in increased expression of TNFSF10 mRNA; Capsaicin results in increased expression of TNFSF10 protein
Capsaicin results in increased activity of TNFSF10 protein
CTD PMID:19939880 PMID:22150557 PMID:22200406 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tom1 target of myb1 membrane trafficking protein decreases expression EXP Capsaicin results in decreased expression of TOM1 mRNA CTD PMID:20349343 NCBI chr19:13,405,482...13,440,384
Ensembl chr19:13,405,501...13,440,384
JBrowse link
G Tp53 tumor protein p53 decreases degradation
affects response to substance
increases phosphorylation
multiple interactions
increases expression
increases degradation
ISO Capsaicin results in decreased degradation of TP53 protein
TP53 affects the susceptibility to Capsaicin
Capsaicin results in increased phosphorylation of TP53 protein
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased expression of TP53 protein]; 3-aminobenzamide inhibits the reaction [Capsaicin results in increased expression of TP53 protein]; 3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in increased degradation of TP53 protein]; Caffeine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; Capsaicin promotes the reaction [resveratrol results in increased expression of TP53 protein]; Capsaicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein; Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein; Capsaicin results in increased phosphorylation of and results in increased expression of TP53 protein; CAT protein inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]; MAPK8 protein promotes the reaction [Capsaicin results in decreased degradation of TP53 protein]; pifithrin inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; pyrazolanthrone inhibits the reaction [Capsaicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein]; resveratrol promotes the reaction [Capsaicin results in increased expression of TP53 protein]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]]; TP53 affects the reaction [Capsaicin results in decreased expression of MDM2 protein]; TP53 affects the reaction [Capsaicin results in increased expression of NOS1 protein]; TP53 affects the reaction [Capsaicin results in increased expression of NOS3 protein]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]]; TP53 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]; Tunicamycin promotes the reaction [Capsaicin results in increased degradation of TP53 protein]
Capsaicin results in increased expression of TP53 mRNA; Capsaicin results in increased expression of TP53 protein
Capsaicin results in increased expression of TRP53
CTD PMID:9461043 PMID:14871840 PMID:16540674 PMID:17292493 PMID:18991268 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Capsaicin results in increased expression of TPI1 mRNA; Capsaicin results in increased expression of TPI1 protein CTD PMID:19891501 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Traf3 Tnf receptor-associated factor 3 increases expression ISO Capsaicin results in increased expression of TRAF3 mRNA CTD PMID:19502594 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481
JBrowse link
G Traf4 Tnf receptor associated factor 4 increases expression ISO Capsaicin results in increased expression of TRAF4 mRNA CTD PMID:19502594 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284
JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 increases expression EXP Capsaicin results in increased expression of TRAFD1 mRNA CTD PMID:16278290 NCBI chr12:35,165,606...35,179,525
Ensembl chr12:35,165,606...35,179,525
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions
increases activity
decreases expression
EXP
ISO
Calcium affects the reaction [Capsaicin inhibits the reaction [TRPA1 protein affects the susceptibility to mustard oil]]
Capsaicin results in increased activity of TRPA1 protein
Capsaicin results in decreased expression of TRPA1 mRNA
CTD PMID:17590514 PMID:18079164 PMID:29054683 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 increases expression EXP Capsaicin results in increased expression of TRPC5 mRNA CTD PMID:16278290 NCBI chr  X:107,946,163...108,230,978
Ensembl chr  X:107,939,131...108,230,991
JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 decreases expression
increases activity
EXP
ISO
Capsaicin results in decreased expression of TRPM8 mRNA
Capsaicin results in increased activity of TRPM8 protein
CTD PMID:18079164 PMID:29054683 NCBI chr 9:88,897,039...88,990,167
Ensembl chr 9:88,903,880...88,988,552
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 affects response to substance
decreases expression
increases response to substance
increases activity
increases expression
affects binding
affects localization
multiple interactions
decreases response to substance
ISO
EXP
TRPV1 protein affects the susceptibility to Capsaicin; TRPV1 protein polymorphism affects the susceptibility to Capsaicin analog
Capsaicin results in decreased expression of TRPV1 mRNA; Capsaicin results in decreased expression of TRPV1 protein
TRPV1 protein results in increased susceptibility to Capsaicin; TRPV1 protein results in increased susceptibility to Capsaicin analog
Capsaicin results in increased activity of TRPV1 protein
Capsaicin results in increased expression of TRPV1 mRNA; Capsaicin results in increased expression of TRPV1 protein
Capsaicin results in increased activity of TRPV1; Capsaicin results in increased activity of TRPV1 protein
Capsaicin binds to TRPV1 protein
Capsaicin affects the localization of TRPV1 protein
Capsaicin analog results in increased activity of TRPV1 protein; Capsaicin results in increased activity of TRPV1; Capsaicin results in increased activity of TRPV1 protein
1-Methyl-3-isobutylxanthine promotes the reaction [Capsaicin results in increased activity of TRPV1]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP promotes the reaction [Capsaicin results in increased activity of TRPV1]; [Capsaicin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; BDKRB2 affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; BDKRB2 affects the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]; Cannabidiol inhibits the reaction [[Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [Capsaicin binds to TRPV1 protein]; Capsaicin binds to and results in increased activity of TRPV1 protein; Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]; capsazepine inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Phosphatidylinositol 4,5-Diphosphate affects the reaction [Capsaicin results in increased activity of TRPV1 protein]]; capsazepine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Colforsin promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Colforsin promotes the reaction [Capsaicin results in increased activity of TRPV1]; Edetic Acid inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; EDN1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Egtazic Acid inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; iodoresiniferatoxin inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Phosphatidylinositol 4,5-Diphosphate affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]; Rimonabant inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; Ruthenium Red inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; Tetradecanoylphorbol Acetate inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]; TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1R mRNA]; TRPV1 inhibits the reaction [Capsaicin results in increased expression of and results in increased activity of MMP9 protein]; TRPV1 promotes the reaction [Capsaicin results in increased uptake of Calcium]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 mRNA]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 protein]; Xenon inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]
1-Methyl-3-isobutylxanthine promotes the reaction [Capsaicin results in increased activity of TRPV1]; 2,4-bis(4'-fluorophenethylamino)-6-(3'-(N,N-dimethylamino)propylamino)-1,3,5-triazine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 3-amino-5-((2-((2-methoxyethyl)amino)-6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yl)oxy)quinoxalin-2(1H)-one inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP promotes the reaction [Capsaicin results in increased activity of TRPV1]; [Capsaicin binds to and affects the activity of TRPV1 protein] which results in increased secretion of Adenosine Triphosphate; [Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; Acrylamide analog inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; benzimidazole analog inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Bupivacaine affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; Butyrates promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Butyrates promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; Calcium affects the reaction [mustard oil inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; Capsaicin binds to and results in increased activity of TRPV1 protein; Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TRPV1 mRNA]; Capsaicin promotes the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Capsaicin promotes the reaction [TRPV1 protein binds to TRPV1 protein]; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; chelerythrine inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]; Colforsin promotes the reaction [Capsaicin results in increased activity of TRPV1]; diarylpropionitrile inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Docosahexaenoic Acids promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Eicosapentaenoic Acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Estradiol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; fulvestrant inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; gamma-Linolenic Acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; geldanamycin affects the reaction [Capsaicin results in increased activity of TRPV1]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]; JYL 1421 inhibits the reaction [Capsaicin binds to TRPV1 protein]; JYL 1421 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; KJM 429 inhibits the reaction [Capsaicin binds to TRPV1 protein]; Lidocaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; MCS-18 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; N-((4-(((3-(6-((2-amino-1,3-benzothiazol-4-yl)oxy)pyrimidin-4-yl)) -6-(trifluoromethyl)pyridin-2-yl)amino)methyl)-2-fluorophenyl)methanesulfonamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Octoxynol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; oxophenylarsine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; oxophenylarsine inhibits the reaction [Lidocaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]; Serotonin promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]; Tamoxifen inhibits the reaction [diarylpropionitrile inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]]; Tamoxifen inhibits the reaction [Estradiol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]]; tert-butyl-2-(6-((2-(acetylamino)-1,3-benzothiazol-4-yl)oxy)pyrimidin-4-yl)-5-(trifluoromethyl)phenylcarbamate inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Tetracaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; TRPV1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; CALCA protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; Capsaicin binds to and results in increased activity of TRPV1 protein; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; CYBB protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; Linolenic Acids inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; RARRES2 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; TAC1 protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; TRPV1 gene mutant form inhibits the reaction [Capsaicin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased abundance of Reactive Oxygen Species]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; TRPV1 mutant form inhibits the reaction [Capsaicin results in increased abundance of Reactive Oxygen Species]; TRPV1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased transport of Calcium]; TRPV1 results in decreased susceptibility to [Capsaicin co-treated with Tetradecanoylphorbol Acetate]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]
TRPV1 protein results in increased susceptibility to Capsaicin; TRPV1 results in increased susceptibility to Capsaicin
TRPV1 protein mutant form results in decreased susceptibility to Capsaicin; TRPV1 results in decreased susceptibility to Capsaicin
CTD PMID:11140687 PMID:11278420 PMID:11358970 PMID:11606325 PMID:11930156 More... NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases expression EXP Capsaicin results in increased expression of TRPV4 mRNA CTD PMID:16278290 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 multiple interactions
increases response to substance
ISO TRPV6 protein promotes the reaction [Capsaicin results in increased abundance of Calcium]; TRPV6 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]
TRPV6 protein results in increased susceptibility to Capsaicin
CTD PMID:17292493 NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017
JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO Capsaicin results in decreased expression of TXNIP mRNA CTD PMID:33512557 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ucp1 uncoupling protein 1 decreases expression
multiple interactions
EXP Capsaicin results in decreased expression of UCP1 mRNA; Capsaicin results in decreased expression of UCP1 protein
Capsaicin promotes the reaction [Dietary Fats results in increased expression of UCP1 mRNA]
CTD PMID:18079164 PMID:20359164 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Ucp2 uncoupling protein 2 affects response to substance
multiple interactions
ISO
EXP
UCP2 protein polymorphism affects the susceptibility to Capsaicin analog
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of UCP2 mRNA]
CTD PMID:19056576 PMID:20359164 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ucp3 uncoupling protein 3 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of UCP3 protein] CTD PMID:20517883 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Capsaicin CTD PMID:14557274 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of Capsaicin CTD PMID:14557274 NCBI chr 9:88,727,094...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Capsaicin CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Unc13a unc-13 homolog A increases expression EXP Capsaicin results in increased expression of UNC13A mRNA CTD PMID:16278290 NCBI chr16:18,336,229...18,381,811
Ensembl chr16:18,336,229...18,381,872
JBrowse link
G Usp5 ubiquitin specific peptidase 5 decreases expression EXP Capsaicin results in decreased expression of USP5 mRNA CTD PMID:20349343 NCBI chr 4:157,619,643...157,634,711
Ensembl chr 4:157,619,643...157,634,711
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 decreases expression EXP Capsaicin results in decreased expression of VAMP2 mRNA CTD PMID:20349343 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression
multiple interactions
ISO
EXP
Capsaicin results in increased expression of VCAM1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of VCAM1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of VCAM1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of VCAM1 protein]
CTD PMID:9973426 PMID:22150557 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
increases expression
multiple interactions
decreases activity
increases secretion
ISO
EXP
Capsaicin results in decreased expression of VEGFA protein
Capsaicin results in increased expression of VEGFA mRNA
Capsaicin results in increased expression of VEGFA protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of VEGFA protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of VEGFA protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of VEGFA protein]
Capsaicin results in decreased activity of VEGFA
Capsaicin results in increased secretion of VEGFA protein
CTD PMID:12242509 PMID:14744780 PMID:17505005 PMID:21310942 PMID:22150557 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of VIM protein] CTD PMID:20359164 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vip vasoactive intestinal peptide decreases expression
increases expression
EXP Capsaicin results in decreased expression of VIP mRNA
Capsaicin results in increased expression of VIP mRNA
CTD PMID:8971780 PMID:20349343 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
JBrowse link
G Vom1r90 vomeronasal 1 receptor 90 increases expression EXP Capsaicin results in increased expression of VOM1R90 mRNA CTD PMID:16278290 NCBI chr 4:122,139,053...122,148,056
Ensembl chr 4:122,137,880...122,148,193
JBrowse link
G Wnt7a Wnt family member 7A decreases expression EXP Capsaicin results in decreased expression of WNT7A mRNA CTD PMID:16278290 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981
JBrowse link
G Zfp2 zinc finger protein 2 increases expression EXP Capsaicin results in increased expression of ZFP2 mRNA CTD PMID:16278290 NCBI chr10:35,209,187...35,228,849
Ensembl chr10:35,207,260...35,228,853
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    role 19746
      biological role 19746
        pharmacological role 18832
          agonist 18256
            TRPV1 agonist 498
              capsaicin 497
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            organic group 18713
                              organic divalent group 18697
                                organodiyl group 18697
                                  carbonyl group 18646
                                    carbonyl compound 18646
                                      carboxylic acid 18341
                                        carboacyl group 17466
                                          univalent carboacyl group 17466
                                            carbamoyl group 17282
                                              carboxamide 17282
                                                monocarboxylic acid amide 15009
                                                  fatty amide 774
                                                    capsaicinoid 500
                                                      capsaicin 497
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