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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:canthin-6-one
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Accession:CHEBI:3363 term browser browse the term
Definition:An indole alkaloid that is 6H-indolo[3,2,1-de][1,5]naphthyridine substituted by an oxo group at position 6.
Synonyms:related_synonym: 6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one;   Formula=C14H8N2O;   InChI=1S/C14H8N2O/c17-13-6-5-11-14-10(7-8-15-11)9-3-1-2-4-12(9)16(13)14/h1-8H;   InChIKey=ZERVJPYNQLONEK-UHFFFAOYSA-N;   SMILES=O=c1ccc2nccc3c4ccccc4n1c23
 xref: CAS:479-43-6;   KEGG:C09098;   KNApSAcK:C00001701;   PMID:19325221;   PMID:21134431;   PMID:21236329;   Patent:US2011059977;   Reaxys:181378



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9-hydroxycanthin-6-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases cleavage ISO 9-hydroxycanthin-6-one results in increased cleavage of CASP3 protein CTD PMID:29225138 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases cleavage ISO 9-hydroxycanthin-6-one results in increased cleavage of CASP8 protein CTD PMID:29225138 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases cleavage ISO 9-hydroxycanthin-6-one results in increased cleavage of CASP9 protein CTD PMID:29225138 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO 9-hydroxycanthin-6-one results in decreased expression of CCL2 mRNA CTD PMID:29225138 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO 9-hydroxycanthin-6-one results in decreased expression of CCL5 mRNA CTD PMID:29225138 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19844
    role 19820
      biological role 19818
        biochemical role 19525
          metabolite 19512
            canthin-6-one 5
              1-methoxycanthinone 0
              10-hydroxycanthin-6-one 0
              9-hydroxycanthin-6-one 5
              9-methoxycanthin-6-one 0
              drymaritin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    p-block element atom 19792
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            heteroorganic entity 19486
                              organochalcogen compound 19249
                                organooxygen compound 19167
                                  carbonyl compound 18890
                                    ketone 17180
                                      alpha,beta-unsaturated ketone 9972
                                        enone 9972
                                          canthin-6-one 5
                                            1-methoxycanthinone 0
                                            10-hydroxycanthin-6-one 0
                                            9-hydroxycanthin-6-one 5
                                            9-methoxycanthin-6-one 0
                                            drymaritin 0
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