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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:canthin-6-one
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Accession:CHEBI:3363 term browser browse the term
Definition:An indole alkaloid that is 6H-indolo[3,2,1-de][1,5]naphthyridine substituted by an oxo group at position 6.
Synonyms:related_synonym: 6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one;   Formula=C14H8N2O;   InChI=1S/C14H8N2O/c17-13-6-5-11-14-10(7-8-15-11)9-3-1-2-4-12(9)16(13)14/h1-8H;   InChIKey=ZERVJPYNQLONEK-UHFFFAOYSA-N;   SMILES=O=c1ccc2nccc3c4ccccc4n1c23
 xref: CAS:479-43-6;   KEGG:C09098;   KNApSAcK:C00001701;   PMID:19325221;   PMID:21134431;   PMID:21236329;   Patent:US2011059977;   Reaxys:181378


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9-hydroxycanthin-6-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases cleavage ISO 9-hydroxycanthin-6-one results in increased cleavage of CASP3 protein CTD PMID:29225138 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases cleavage ISO 9-hydroxycanthin-6-one results in increased cleavage of CASP8 protein CTD PMID:29225138 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases cleavage ISO 9-hydroxycanthin-6-one results in increased cleavage of CASP9 protein CTD PMID:29225138 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO 9-hydroxycanthin-6-one results in decreased expression of CCL2 mRNA CTD PMID:29225138 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO 9-hydroxycanthin-6-one results in decreased expression of CCL5 mRNA CTD PMID:29225138 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        biochemical role 19304
          metabolite 19285
            canthin-6-one 5
              1-methoxycanthinone 0
              10-hydroxycanthin-6-one 0
              9-hydroxycanthin-6-one 5
              9-methoxycanthin-6-one 0
              drymaritin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic group 18527
                              organic divalent group 18520
                                organodiyl group 18520
                                  carbonyl group 18427
                                    carbonyl compound 18427
                                      ketone 16171
                                        alpha,beta-unsaturated ketone 8522
                                          enone 8522
                                            canthin-6-one 5
                                              1-methoxycanthinone 0
                                              10-hydroxycanthin-6-one 0
                                              9-hydroxycanthin-6-one 5
                                              9-methoxycanthin-6-one 0
                                              drymaritin 0
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