Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulfonate
go back to main search page
Accession:CHEBI:33543 term browser browse the term
Definition:The sulfur oxoanion formed by deprotonation of sulfonic acid.
Synonyms:exact_synonym: hydridotrioxidosulfate(1-)
 related_synonym: Formula=HO3S;   InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)/p-1;   InChIKey=BDHFUVZGWQCTTF-UHFFFAOYSA-M;   SHO3(-);   SMILES=[H]S([O-])(=O)=O;   sulfonates
 xref: Gmelin:971569
 cyclic_relationship: is_conjugate_base_of CHEBI:29214


show annotations for term's descendants           Sort by:
 
acid red 29 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO chromotrope 2R binds to ALB protein CTD PMID:19347248 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
benzenesulfonates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc10a1 solute carrier family 10 member 1 multiple interactions ISO Benzenesulfonates analog inhibits the reaction [SLC10A1 protein results in increased transport of Taurocholic Acid] CTD PMID:22641618 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
Congo Red term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions
affects binding
EXP
ISO
Congo Red inhibits the reaction [APP protein binds to APP protein]
Congo Red binds to APP protein
CTD PMID:17323972 PMID:17406451 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Prnp prion protein decreases expression ISO Congo Red results in decreased expression of PRNP protein alternative form CTD PMID:11994310 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
indigo carmine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions
affects binding
ISO Indigo Carmine binds to and results in increased activity of AHR protein
Indigo Carmine binds to AHR protein
CTD PMID:11425848 PMID:15001395 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP [ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in decreased expression of CHRNA4 protein CTD PMID:23429044 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP [ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in increased expression of CHRNB2 protein CTD PMID:23429044 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions
ISO
EXP
Indigo Carmine results in increased activity of CYP1A1 protein
Indigo Carmine results in increased expression of CYP1A1 mRNA
Indigo Carmine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
CTD PMID:15001395 PMID:15882963 PMID:18493746 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions EXP [ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in decreased expression of GRIN2A protein; [ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in increased expression of GRIN2A protein CTD PMID:23429044 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
indocyanine green term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Indocyanine Green inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Indocyanine Green results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 affects export ISO ABCB4 protein affects the export of Indocyanine Green CTD PMID:11302927 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Indocyanine Green results in increased expression of BAX mRNA; Indocyanine Green results in increased expression of BAX protein CTD PMID:23675521 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Casp9 caspase 9 increases expression ISO Indocyanine Green results in increased expression of CASP9 mRNA; Indocyanine Green results in increased expression of CASP9 protein CTD PMID:23675521 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Slc16a2 solute carrier family 16 member 2 multiple interactions ISO Indocyanine Green inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine] CTD PMID:28119167 NCBI chr  X:74,578,600...74,706,068
Ensembl chr  X:74,577,131...74,706,214
JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO Indocyanine Green inhibits the reaction [SLC22A7 protein results in increased uptake of Glutarates] CTD PMID:12065749 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions EXP Indocyanine Green inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
lucifer yellow dye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases uptake
increases transport
ISO 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [ABCG2 protein results in increased uptake of lucifer yellow]; Novobiocin inhibits the reaction [ABCG2 protein results in increased uptake of lucifer yellow]; Omeprazole inhibits the reaction [ABCG2 protein results in increased transport of lucifer yellow] CTD PMID:31348918 PMID:32305507 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
metamizole sodium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone multiple interactions EXP Dipyrone inhibits the reaction [IL1B protein results in increased secretion of CRH protein]; Dipyrone inhibits the reaction [IL6 protein results in increased secretion of CRH protein]; Dipyrone inhibits the reaction [Lipopolysaccharides results in increased secretion of CRH protein]; Dipyrone inhibits the reaction [TNF protein results in increased secretion of CRH protein] CTD PMID:11852909 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Dipyrone inhibits the reaction [IL1B protein results in increased secretion of CRH protein] CTD PMID:11852909 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Dipyrone inhibits the reaction [IL6 protein results in increased secretion of CRH protein] CTD PMID:11852909 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity ISO Dipyrone analog results in decreased activity of PTGS1 protein; Dipyrone results in decreased activity of PTGS1 protein CTD PMID:12242329 PMID:16141368 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions EXP Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of TGFA protein] CTD PMID:15309881 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Dipyrone inhibits the reaction [TNF protein results in increased secretion of CRH protein] CTD PMID:11852909 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
sodium taurocholate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpinf1 serpin family F member 1 EXP taurocholate decreased activity of Serpinf1 protein in plasma RGD PMID:10360224 RGD:8661651 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
tartrazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases activity EXP Tartrazine results in decreased activity of CAT protein CTD PMID:20678534 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP [ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in decreased expression of CHRNA4 protein CTD PMID:23429044 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP [ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in increased expression of CHRNB2 protein CTD PMID:23429044 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions
ISO Tartrazine results in increased activity of ESR1 protein
fulvestrant inhibits the reaction [Tartrazine results in increased activity of ESR1 protein]
CTD PMID:22562034 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions EXP [ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in decreased expression of GRIN2A protein; [ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in increased expression of GRIN2A protein CTD PMID:23429044 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [Tartrazine results in increased expression of TFF1 mRNA] CTD PMID:22562034 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    chemical entity 19761
      atom 19759
        nonmetal atom 19641
          sulfur atom 16286
            sulfur molecular entity 16286
              sulfur oxoanion 533
                sulfonate 28
                  genistein 4',7-disulfate(2-) 0
                  organosulfonate oxoanion + 28
                  sulfonato group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      chalcogen 19382
                        oxygen atom 19345
                          oxygen molecular entity 19345
                            oxide 11643
                              oxoanion 8755
                                chalcogen oxoanion 534
                                  sulfur oxoanion 533
                                    sulfonate 28
                                      genistein 4',7-disulfate(2-) 0
                                      organosulfonate oxoanion + 28
                                      sulfonato group 0
paths to the root