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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glyceric acid
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Accession:CHEBI:33508 term browser browse the term
Definition:A trionic acid that consists of propionic acid substituted at positions 2 and 3 by hydroxy groups.
Synonyms:exact_synonym: 2,3-dihydroxypropanoic acid
 related_synonym: 2,3-dihydroxypropionic acid;   Formula=C3H6O4;   Gro;   InChI=1S/C3H6O4/c4-1-2(5)3(6)7/h2,4-5H,1H2,(H,6,7);   InChIKey=RBNPOMFGQQGHHO-UHFFFAOYSA-N;   SMILES=OCC(O)C(O)=O
 alt_id: CHEBI:24348;   CHEBI:24349;   CHEBI:33846
 xref: Beilstein:1721417;   CAS:473-81-4;   Gmelin:164608
 xref_mesh: MESH:C042971
 xref: PMID:14957916;   PMID:17439666;   PMID:21071844;   PMID:21701101;   PMID:21852749;   PMID:22226201;   Reaxys:1721417;   Wikipedia:Glyceric_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:33871


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glyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glyceric acid] CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
2,3-bisphospho-D-glyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf6 ADP-ribosylation factor 6 multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]]; 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein mutant form promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]] CTD PMID:10931844 NCBI chr 6:91,697,109...91,698,257
Ensembl chr 6:91,697,109...91,698,255
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of BGLAP protein CTD PMID:16857255 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Pld1 phospholipase D1 decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of PLD1 protein CTD PMID:16857255 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Sts steroid sulfatase multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
2,3-bisphosphoglyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf6 ADP-ribosylation factor 6 multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]]; 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein mutant form promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]] CTD PMID:10931844 NCBI chr 6:91,697,109...91,698,257
Ensembl chr 6:91,697,109...91,698,255
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of BGLAP protein CTD PMID:16857255 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Pld1 phospholipase D1 decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of PLD1 protein CTD PMID:16857255 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Sts steroid sulfatase multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
3-phosphoglyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased chemical synthesis of sodium arsenite; [GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog; heptelidic acid inhibits the reaction [[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog] CTD PMID:15788719 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 3-phosphoglycerate] CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
D-glyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of glyceric acid
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glyceric acid]
CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    role 19804
      biological role 19804
        biochemical role 19339
          metabolite 19319
            fundamental metabolite 12653
              glyceric acid 6
                2,3-bisphosphoglyceric acid + 4
                2-phosphoglyceric acid + 0
                3-ADP-2-phosphoglyceric acid 0
                3-phosphoglyceric acid + 2
                D-glyceric acid + 5
                L-glyceric acid 0
                N-acetyl-S-glyceroyl-L-cysteine 0
                glyceroyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic group 18550
                              organic divalent group 18541
                                organodiyl group 18541
                                  carbonyl group 18447
                                    carbonyl compound 18447
                                      carboxylic acid 18125
                                        monocarboxylic acid 17494
                                          fatty acid 15997
                                            saturated fatty acid 15972
                                              propionic acid 3672
                                                glyceric acid 6
                                                  2,3-bisphosphoglyceric acid + 4
                                                  2-phosphoglyceric acid + 0
                                                  3-ADP-2-phosphoglyceric acid 0
                                                  3-phosphoglyceric acid + 2
                                                  D-glyceric acid + 5
                                                  L-glyceric acid 0
                                                  N-acetyl-S-glyceroyl-L-cysteine 0
                                                  glyceroyl group 0
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