Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:halogen oxoanion
go back to main search page
Accession:CHEBI:33443 term browser browse the term
Synonyms:related_synonym: halogen oxoanions


show annotations for term's descendants           Sort by:
 
chlorite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity ISO chlorite results in increased activity of ACHE protein CTD PMID:27478981 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Cat catalase decreases activity ISO chlorite results in decreased activity of CAT protein CTD PMID:27478981 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO chlorite results in decreased activity of G6PD protein CTD PMID:27478981 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO chlorite results in decreased activity of GSR protein CTD PMID:27478981 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G H2ax H2A.X variant histone multiple interactions EXP chlorite promotes the reaction [Bromates results in increased phosphorylation of H2AX protein] CTD PMID:21864635 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Ldhb lactate dehydrogenase B increases activity ISO chlorite results in increased activity of LDHB protein CTD PMID:27478981 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Sod1 superoxide dismutase 1 increases activity ISO chlorite results in increased activity of SOD1 protein CTD PMID:27478981 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity ISO chlorite results in decreased activity of TXNRD1 protein CTD PMID:27478981 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
perchlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 affects expression EXP perchlorate affects the expression of AQP1 mRNA CTD PMID:21623536 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Ca5a carbonic anhydrase 5A decreases activity ISO perchlorate results in decreased activity of CA5A protein CTD PMID:15664814 NCBI chr19:54,731,829...54,761,697
Ensembl chr19:54,731,859...54,761,670
JBrowse link
G Ca9 carbonic anhydrase 9 decreases activity ISO perchlorate results in decreased activity of CA9 protein CTD PMID:15664814 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO perchlorate results in decreased activity of CA1 protein CTD PMID:15664814 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO perchlorate results in decreased activity of CA2 protein CTD PMID:15664814 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
EXP perchlorate results in increased activity of CASP3 protein
Sodium Iodide promotes the reaction [perchlorate results in increased activity of CASP3 protein]
CTD PMID:11834455 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [sodium perchlorate results in increased abundance of perchlorate] which results in increased expression of FOS protein CTD PMID:30991129 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Mir133a1 microRNA 133a-1 multiple interactions ISO [Methimazole co-treated with perchlorate] results in increased expression of MIR133A1 mRNA CTD PMID:20808432 NCBI chr18:2,052,478...2,052,564 JBrowse link
G Mir133b microRNA 133b multiple interactions ISO [Methimazole co-treated with perchlorate] results in increased expression of MIR133B mRNA CTD PMID:20808432 NCBI chr 9:26,795,649...26,795,732
Ensembl chr 9:26,795,649...26,795,732
JBrowse link
G Mir135a microRNA 135a multiple interactions ISO [Methimazole co-treated with perchlorate] results in increased expression of MIR135A mRNA CTD PMID:20808432 NCBI chr 7:32,894,877...32,894,976
Ensembl chr 7:32,894,877...32,894,976
JBrowse link
G Mir135b microRNA 135b multiple interactions ISO [Methimazole co-treated with perchlorate] results in increased expression of MIR135B mRNA CTD PMID:20808432 NCBI chr13:48,976,986...48,977,082
Ensembl chr13:48,976,986...48,977,082
JBrowse link
G Mir148a microRNA 148a multiple interactions ISO [Methimazole co-treated with perchlorate] results in decreased expression of MIR148A mRNA CTD PMID:20808432 NCBI chr 4:81,013,269...81,013,365
Ensembl chr 4:81,013,269...81,013,365
JBrowse link
G Mir206 microRNA 206 multiple interactions ISO [Methimazole co-treated with perchlorate] results in increased expression of MIR206 mRNA CTD PMID:20808432 NCBI chr 9:26,791,764...26,791,847
Ensembl chr 9:26,791,764...26,791,847
JBrowse link
G Papss1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 multiple interactions ISO perchlorate binds to and results in decreased activity of PAPSS1 protein CTD PMID:15065880 NCBI chr 2:236,605,695...236,680,772
Ensembl chr 2:236,605,695...236,680,772
JBrowse link
G Slc22a3 solute carrier family 22 member 3 affects expression EXP perchlorate affects the expression of SLC22A3 mRNA CTD PMID:21623536 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
JBrowse link
G Slc5a5 solute carrier family 5 member 5 increases expression
affects expression
decreases activity
multiple interactions
ISO
EXP
perchlorate results in increased expression of SLC5A5 protein
perchlorate affects the expression of SLC5A5 mRNA
perchlorate results in decreased activity of SLC5A5 protein
perchlorate inhibits the reaction [mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]]; perchlorate inhibits the reaction [SLC5A5 protein results in increased abundance of Sodium Iodide]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]
CTD PMID:12601449, PMID:14633711, PMID:15347726, PMID:15850642, PMID:15941870, PMID:16987991, PMID:17332529, PMID:21623536 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
G Tg thyroglobulin decreases expression ISO perchlorate results in decreased expression of TG protein CTD PMID:17332529 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tshb thyroid stimulating hormone subunit beta increases expression
multiple interactions
ISO perchlorate results in increased expression of TSHB protein
[Iodides deficiency co-treated with perchlorate] results in increased expression of TSHB protein
CTD PMID:17332529, PMID:20439182 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
potassium bromate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO potassium bromate results in decreased expression of A2M mRNA CTD PMID:30008028 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA] CTD PMID:27082013 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
affects expression
ISO [potassium bromate co-treated with bisphenol A] affects the expression of AKR1B10 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AKR1B10 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AKR1B10 mRNA] CTD PMID:27082013 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression EXP potassium bromate results in increased expression of AKR1C2 mRNA CTD PMID:23588252 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 decreases expression ISO potassium bromate results in decreased expression of AMIGO2 mRNA CTD PMID:30008028 NCBI chr 7:138,704,124...138,707,221
Ensembl chr 7:138,704,126...138,707,221
JBrowse link
G Anos1 anosmin 1 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of WFDC17 mRNA] CTD PMID:27082013 Ensembl chr10:70,999,780...71,000,627 JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO potassium bromate results in increased expression of APEX1 mRNA CTD PMID:22539617 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G App amyloid beta precursor protein increases expression ISO potassium bromate results in increased expression of APP mRNA CTD PMID:30008028 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Areg amphiregulin multiple interactions
affects expression
ISO [potassium bromate co-treated with bisphenol A] affects the expression of AREG mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AREG mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AREG mRNA] CTD PMID:27082013 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arg1 arginase 1 decreases expression ISO potassium bromate results in decreased expression of ARG1 mRNA CTD PMID:30008028 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) affects expression ISO potassium bromate affects the expression of ASNS mRNA CTD PMID:30008028 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
EXP
ISO
potassium bromate results in increased expression of ATF3 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of ATF3 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ATF3 mRNA]
CTD PMID:23588252, PMID:27082013 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO potassium bromate results in decreased expression of ATM mRNA CTD PMID:22539617 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression ISO potassium bromate results in decreased expression of ATP1B1 mRNA CTD PMID:30008028 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 decreases expression EXP potassium bromate results in decreased expression of ATP2B3 mRNA CTD PMID:23588252 NCBI chr  X:157,236,400...157,312,028
Ensembl chr  X:157,239,306...157,312,028
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression ISO potassium bromate results in decreased expression of BAAT mRNA CTD PMID:30008028 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO potassium bromate results in increased expression of BAX mRNA CTD PMID:30559759 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression ISO potassium bromate results in decreased expression of BBOX1 mRNA CTD PMID:30008028 NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
JBrowse link
G Blnk B-cell linker affects expression
multiple interactions
ISO potassium bromate affects the expression of BLNK mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BLNK mRNA]
CTD PMID:27082013 NCBI chr 1:260,187,023...260,254,490
Ensembl chr 1:260,186,967...260,254,600
JBrowse link
G Bmf Bcl2 modifying factor affects expression
multiple interactions
ISO potassium bromate affects the expression of BMF mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BMF mRNA]
CTD PMID:27082013 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO potassium bromate results in increased expression of BRCA1 mRNA CTD PMID:22539617 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP potassium bromate results in decreased expression of CA3 mRNA CTD PMID:23588252 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Ca6 carbonic anhydrase 6 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of CAR6 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CAR6 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CAR6 mRNA] CTD PMID:27082013 NCBI chr 5:167,226,246...167,244,786
Ensembl chr 5:167,226,246...167,244,786
JBrowse link
G Cars cysteinyl-tRNA synthetase decreases expression ISO potassium bromate results in decreased expression of CARS1 mRNA CTD PMID:30559759 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Cat catalase decreases activity
multiple interactions
increases activity
ISO
EXP
potassium bromate results in decreased activity of CAT protein
vanillin inhibits the reaction [potassium bromate results in increased activity of CAT protein]
Taurine inhibits the reaction [potassium bromate results in decreased activity of CAT protein]
CTD PMID:22012894, PMID:25213677, PMID:26296324, PMID:27074584 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions
EXP
ISO
potassium bromate results in increased expression of CCL20 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CCL20 mRNA]
CTD PMID:23588252, PMID:27082013 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccnb1 cyclin B1 multiple interactions
increases expression
ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased expression of CCNB1 protein] CTD PMID:20067818 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccno cyclin O decreases expression ISO potassium bromate results in decreased expression of CCNO mRNA CTD PMID:22539617 NCBI chr 2:44,857,043...44,860,317
Ensembl chr 2:44,857,213...44,860,315
JBrowse link
G Cdhr1 cadherin-related family member 1 increases expression EXP potassium bromate results in increased expression of CDHR1 mRNA CTD PMID:23588252 NCBI chr16:14,328,161...14,348,049
Ensembl chr16:14,328,160...14,348,046
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases phosphorylation ISO potassium bromate results in increased phosphorylation of CDK1 protein CTD PMID:20067818 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
affects methylation
affects expression
multiple interactions
ISO
EXP
potassium bromate results in increased expression of CDKN1A mRNA; potassium bromate results in increased expression of CDKN1A protein
potassium bromate affects the methylation of CDKN1A gene
potassium bromate affects the expression of CDKN1A mRNA; potassium bromate affects the expression of CDKN1A protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; Azacitidine inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; trichostatin A inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]
CTD PMID:20067818, PMID:23588252, PMID:23811332, PMID:25015661, PMID:30008028, PMID:30559759 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cfd complement factor D decreases expression EXP potassium bromate results in decreased expression of CFD mRNA CTD PMID:23588252 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression EXP potassium bromate results in increased expression of CHAC1 mRNA CTD PMID:23588252 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Cldn2 claudin 2 decreases expression ISO potassium bromate results in decreased expression of CLDN2 mRNA CTD PMID:30008028 NCBI chr  X:111,122,552...111,133,188
Ensembl chr  X:111,122,552...111,137,769
JBrowse link
G Clu clusterin increases expression EXP potassium bromate results in increased expression of CLU protein CTD PMID:23159986, PMID:23588252, PMID:23811332 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Coch cochlin decreases expression EXP potassium bromate results in decreased expression of COCH mRNA CTD PMID:23588252 NCBI chr 6:72,359,702...72,373,710
Ensembl chr 6:72,359,791...72,373,695
JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP potassium bromate results in increased expression of COMT mRNA CTD PMID:23588252 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression EXP potassium bromate results in increased expression of CSRP3 mRNA CTD PMID:23588252 NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
JBrowse link
G Cth cystathionine gamma-lyase increases methylation ISO potassium bromate results in increased methylation of CTH promoter CTD PMID:30559759 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CXCL3 mRNA] CTD PMID:27082013 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 decreases expression
increases expression
EXP potassium bromate results in decreased expression of CYP2C7 mRNA
potassium bromate results in increased expression of CYP2C7 mRNA
CTD PMID:23588252 NCBI chr 1:147,422,999...148,119,979
Ensembl chr 1:148,053,687...148,119,857
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
affects expression
ISO [potassium bromate co-treated with bisphenol A] affects the expression of CYP2D22 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CYP2D22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of CYP2D22 mRNA] CTD PMID:27082013 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO potassium bromate results in increased expression of DDB2 mRNA CTD PMID:30559759 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO potassium bromate results in increased expression of DDIT3 mRNA CTD PMID:30008028 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dio3 iodothyronine deiodinase 3 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA] CTD PMID:27082013 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
JBrowse link
G Dsc1 desmocollin 1 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of DSC1 mRNA] CTD PMID:27082013 NCBI chr18:11,877,918...11,906,828
Ensembl chr18:11,877,561...11,906,827
JBrowse link
G Dusp2 dual specificity phosphatase 2 affects expression
multiple interactions
ISO potassium bromate affects the expression of DUSP2 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of DUSP2 mRNA]
CTD PMID:27082013 NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
JBrowse link
G Egr4 early growth response 4 multiple interactions
affects expression
ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of EGR4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of EGR4 mRNA] CTD PMID:27082013 NCBI chr 4:117,293,620...117,296,082
Ensembl chr 4:117,293,620...117,296,082
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit decreases expression ISO potassium bromate results in decreased expression of ERCC4 mRNA CTD PMID:22539617 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor affects response to substance
multiple interactions
ISO ERCC6 protein affects the susceptibility to potassium bromate
veliparib promotes the reaction [ERCC6 protein affects the susceptibility to potassium bromate]
CTD PMID:25136123 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Ereg epiregulin increases expression ISO potassium bromate results in increased expression of EREG mRNA CTD PMID:30008028 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO potassium bromate results in increased expression of FAS mRNA CTD PMID:30559759 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO potassium bromate results in increased expression of FBXO22 mRNA CTD PMID:30559759 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO potassium bromate results in decreased expression of FEN1 mRNA CTD PMID:22539617 NCBI chr 1:226,251,516...226,256,160
Ensembl chr 1:226,251,518...226,255,886
JBrowse link
G Fgb fibrinogen beta chain increases expression EXP potassium bromate results in increased expression of FGB mRNA CTD PMID:23588252 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgl2 fibrinogen-like 2 affects expression
multiple interactions
ISO potassium bromate affects the expression of FGL2 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of FGL2 mRNA]
CTD PMID:27082013 NCBI chr 4:10,323,598...10,329,241
Ensembl chr 4:10,323,607...10,329,241
JBrowse link
G Fry FRY microtubule binding protein multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of FRY mRNA] CTD PMID:27082013 NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO potassium bromate results in increased expression of FTH1 mRNA CTD PMID:30559759 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Fzd2 frizzled class receptor 2 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of FZD2 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of FZD2 mRNA] CTD PMID:27082013 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
decreases activity
EXP Taurine inhibits the reaction [potassium bromate results in decreased activity of G6PD protein] CTD PMID:25213677 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO potassium bromate results in increased expression of GADD45A mRNA CTD PMID:30008028, PMID:30559759 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
increases methylation
ISO potassium bromate results in increased expression of GCLM mRNA
potassium bromate results in increased methylation of GCLM promoter
CTD PMID:30008028, PMID:30559759 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO potassium bromate results in increased expression of GCNT3 mRNA CTD PMID:30559759 NCBI chr 8:76,449,078...76,459,431
Ensembl chr 8:76,449,081...76,452,554
JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO potassium bromate results in increased expression of GPR87 mRNA CTD PMID:30559759 NCBI chr 2:149,398,949...149,418,041
Ensembl chr 2:149,398,949...149,417,212
JBrowse link
G Grifin galectin-related inter-fiber protein decreases expression EXP potassium bromate results in decreased expression of GRIFIN mRNA CTD PMID:23588252 NCBI chr12:16,170,108...16,172,144
Ensembl chr12:16,170,162...16,172,129
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
ISO
EXP
potassium bromate results in decreased activity of GSR protein
Taurine inhibits the reaction [potassium bromate results in decreased activity of GSR protein]
CTD PMID:22012894, PMID:25213677 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 affects expression
multiple interactions
ISO potassium bromate affects the expression of GSTA5 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of GSTA5 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of GSTA5 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of GSTA5 mRNA]
CTD PMID:27082013 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation
ISO
EXP
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein; bisphenol A inhibits the reaction [[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein]
potassium bromate results in increased phosphorylation of H2AX protein
Azacitidine inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]; trichostatin A inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]
CTD PMID:25015661, PMID:25693136 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression EXP potassium bromate results in increased expression of HAVCR1 mRNA; potassium bromate results in increased expression of HAVCR1 protein CTD PMID:23588252, PMID:23811332 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO ceric oxide inhibits the reaction [potassium bromate results in increased expression of HMOX1 mRNA] CTD PMID:25618551, PMID:30008028, PMID:30559759 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression
decreases expression
ISO potassium bromate results in increased expression of HNF4A mRNA
potassium bromate results in decreased expression of HNF4A mRNA
CTD PMID:30008028 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hp haptoglobin affects expression
multiple interactions
ISO potassium bromate affects the expression of HP mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of HP mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of HP mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of HP mRNA]
CTD PMID:27082013 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of HPGD mRNA] CTD PMID:27082013 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis ISO potassium bromate results in increased mutagenesis of HPRT gene
potassium bromate results in increased mutagenesis of HPRT1 gene
CTD PMID:19853637, PMID:22539617 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP potassium bromate results in increased expression of IGFBP1 mRNA CTD PMID:23588252 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Ikzf2 IKAROS family zinc finger 2 affects expression
multiple interactions
ISO potassium bromate affects the expression of IKZF2 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IKZF2 mRNA]
CTD PMID:27082013 NCBI chr 9:76,621,230...76,771,017
Ensembl chr 9:76,621,230...76,768,806
JBrowse link
G Il18r1 interleukin 18 receptor 1 affects expression
multiple interactions
ISO potassium bromate affects the expression of IL18R1 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of IL18R1 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of IL18R1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IL18R1 mRNA]
CTD PMID:27082013 NCBI chr 9:47,184,404...47,217,403
Ensembl chr 9:47,185,443...47,219,175
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP
ISO
potassium bromate results in increased expression of IL1B mRNA
vanillin inhibits the reaction [potassium bromate results in increased expression of IL1B mRNA]
CTD PMID:23588252, PMID:26296324 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il24 interleukin 24 increases expression EXP potassium bromate results in increased expression of IL24 mRNA CTD PMID:23588252 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO potassium bromate results in increased expression of IL6 mRNA
vanillin inhibits the reaction [potassium bromate results in increased expression of IL6 mRNA]
CTD PMID:26296324 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kat2b lysine acetyltransferase 2B multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of KAT2B mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of KAT2B mRNA] CTD PMID:27082013 NCBI chr 9:4,440,982...4,492,949 JBrowse link
G Kirrel3 kirre like nephrin family adhesion molecule 3 decreases expression EXP potassium bromate results in decreased expression of KIRREL3 mRNA CTD PMID:23588252 NCBI chr 8:35,692,525...36,254,755
Ensembl chr 8:36,125,999...36,254,753
JBrowse link
G Klf15 Kruppel-like factor 15 affects expression
multiple interactions
ISO potassium bromate affects the expression of KLF15 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of KLF15 mRNA]
CTD PMID:27082013 NCBI chr 4:122,364,688...122,377,690
Ensembl chr 4:122,365,093...122,377,659
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LCN2 mRNA] CTD PMID:27082013 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lgals12 galectin 12 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LGALS12 mRNA] CTD PMID:27082013 NCBI chr 1:222,891,626...222,903,728
Ensembl chr 1:222,891,626...222,902,320
JBrowse link
G Lig3 DNA ligase 3 decreases expression ISO potassium bromate results in decreased expression of LIG3 mRNA CTD PMID:22539617 NCBI chr10:70,134,734...70,158,051
Ensembl chr10:70,134,729...70,158,055
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO potassium bromate results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:20067818 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO potassium bromate results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:20067818 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO potassium bromate results in increased expression of MDM2 mRNA CTD PMID:30559759 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Me1 malic enzyme 1 increases expression ISO potassium bromate results in increased expression of ME1 mRNA CTD PMID:30008028 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Med1 mediator complex subunit 1 decreases phosphorylation ISO potassium bromate results in decreased phosphorylation of MED1 protein CTD PMID:25068892 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Mir126b microRNA 126b decreases expression ISO potassium bromate results in decreased expression of MIR126 mRNA CTD PMID:30559759 NCBI chr 3:4,042,488...4,042,560 JBrowse link
G Mir134 microRNA 134 increases expression ISO potassium bromate results in increased expression of MIR134 mRNA CTD PMID:30559759 NCBI chr 6:133,884,547...133,884,619
Ensembl chr 6:133,884,531...133,884,633
JBrowse link
G Mir137 microRNA 137 decreases expression ISO potassium bromate results in decreased expression of MIR137 mRNA CTD PMID:30559759 NCBI chr 2:221,658,106...221,658,207
Ensembl chr 2:221,658,106...221,658,207
JBrowse link
G Mir146b microRNA 146b decreases expression ISO potassium bromate results in decreased expression of MIR146B mRNA CTD PMID:30559759 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
JBrowse link
G Mir193a microRNA 193a decreases expression ISO potassium bromate results in decreased expression of MIR193A mRNA CTD PMID:30559759 NCBI chr10:67,065,885...67,065,996
Ensembl chr10:67,065,885...67,065,996
JBrowse link
G Mir193b microRNA 193b decreases expression ISO potassium bromate results in decreased expression of MIR193B mRNA CTD PMID:30559759 NCBI chr14:30,331,049...30,331,131
Ensembl chr14:30,331,049...30,331,131
JBrowse link
G Mir205 microRNA 205 decreases expression ISO potassium bromate results in decreased expression of MIR205 mRNA CTD PMID:30559759 NCBI chr13:112,233,283...112,233,390
Ensembl chr13:112,233,283...112,233,390
JBrowse link
G Mir21 microRNA 21 increases expression ISO potassium bromate results in increased expression of MIR21 mRNA CTD PMID:30559759 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir23b microRNA 23b decreases expression ISO potassium bromate results in decreased expression of MIR23B mRNA CTD PMID:30559759 NCBI chr17:823,222...823,318
Ensembl chr17:823,222...823,318
JBrowse link
G Mir29b1 microRNA 29b-1 decreases expression ISO potassium bromate results in decreased expression of MIR29B1 mRNA CTD PMID:30559759 NCBI chr 4:58,344,310...58,344,390
Ensembl chr 4:58,344,310...58,344,390
JBrowse link
G Mir322 microRNA 322 decreases expression ISO potassium bromate results in decreased expression of MIR424 mRNA CTD PMID:30559759 NCBI chr  X:158,148,161...158,148,255
Ensembl chr  X:158,148,161...158,148,255
JBrowse link
G Mir331 microRNA 331 decreases expression ISO potassium bromate results in decreased expression of MIR331 mRNA CTD PMID:30559759 NCBI chr 7:34,881,095...34,881,190
Ensembl chr 7:34,881,095...34,881,190
JBrowse link
G Mir542 microRNA 542 decreases expression ISO potassium bromate results in decreased expression of MIR542 mRNA CTD PMID:30559759 NCBI chr  X:158,152,146...158,152,224
Ensembl chr  X:158,152,146...158,152,224
JBrowse link
G Mmp15 matrix metallopeptidase 15 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of MMP15 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of MMP15 mRNA] CTD PMID:27082013 NCBI chr19:10,079,881...10,101,380
Ensembl chr19:10,079,765...10,101,451
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
ISO potassium bromate results in increased expression of MT1 mRNA
vanillin inhibits the reaction [potassium bromate results in increased expression of MT1 mRNA]
CTD PMID:27074584 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression
ISO vanillin inhibits the reaction [potassium bromate results in increased expression of MT2 mRNA] CTD PMID:27074584 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression EXP potassium bromate results in increased expression of MTHFD2 mRNA CTD PMID:23588252 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression ISO potassium bromate results in decreased expression of MUC1 mRNA CTD PMID:30008028 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Mutyh mutY DNA glycosylase decreases expression ISO potassium bromate results in decreased expression of MUTYH mRNA CTD PMID:22539617 NCBI chr 5:135,663,328...135,675,348
Ensembl chr 5:135,663,371...135,675,344
JBrowse link
G Myh1 myosin heavy chain 1 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH1 mRNA] CTD PMID:27082013 NCBI chr10:53,740,841...53,764,610
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Myh2 myosin heavy chain 2 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH2 mRNA] CTD PMID:27082013 NCBI chr10:53,711,895...53,738,164
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Mylk3 myosin light chain kinase 3 decreases expression EXP potassium bromate results in decreased expression of MYLK3 mRNA CTD PMID:23588252 NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
JBrowse link
G Nebl nebulette multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NEBL mRNA] CTD PMID:27082013 NCBI chr17:84,141,014...84,247,038
Ensembl chr17:84,140,489...84,488,601
JBrowse link
G Npr3 natriuretic peptide receptor 3 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NPR3 mRNA] CTD PMID:27082013 NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO potassium bromate results in increased expression of NQO1 mRNA CTD PMID:30559759 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases response to substance ISO OGG1 gene mutant form results in decreased susceptibility to potassium bromate CTD PMID:25693136 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Ostn osteocrin multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of OSTN mRNA] CTD PMID:27082013 NCBI chr11:76,851,923...76,888,140
Ensembl chr11:76,851,322...76,888,178
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO potassium bromate results in decreased expression of PHGDH mRNA CTD PMID:30559759 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Plch2 phospholipase C, eta 2 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of PLCH2 mRNA] CTD PMID:27082013 NCBI chr 5:172,386,400...172,455,965
Ensembl chr 5:172,388,598...172,424,081
JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase decreases expression ISO potassium bromate results in decreased expression of PNKP mRNA CTD PMID:22539617 NCBI chr 1:100,853,475...100,859,202
Ensembl chr 1:100,853,902...100,859,084
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO potassium bromate results in increased expression of PPM1D mRNA CTD PMID:30559759 NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases methylation ISO potassium bromate results in decreased methylation of PPP1R15A promoter CTD PMID:30559759 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Prg4 proteoglycan 4 affects expression
multiple interactions
ISO potassium bromate affects the expression of PRG4 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of PRG4 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PRG4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PRG4 mRNA]
CTD PMID:27082013 NCBI chr13:67,672,588...67,688,902
Ensembl chr13:67,672,878...67,688,477
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO potassium bromate results in increased expression of PTGS2 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA]; vanillin inhibits the reaction [potassium bromate results in increased expression of PTGS2 mRNA]
CTD PMID:26296324, PMID:27082013 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 affects expression
multiple interactions
ISO potassium bromate affects the expression of PTPN22 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PTPN22 mRNA]
CTD PMID:27082013 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348
JBrowse link
G Rab3gap2 RAB3 GTPase activating non-catalytic protein subunit 2 increases expression EXP potassium bromate results in increased expression of RAB3GAP2 mRNA CTD PMID:23588252 NCBI chr13:103,157,806...103,229,010
Ensembl chr13:103,157,806...103,228,423
JBrowse link
G Ren renin increases expression EXP potassium bromate results in increased expression of REN1 mRNA CTD PMID:23588252 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Retn resistin decreases expression EXP potassium bromate results in decreased expression of RETN mRNA CTD PMID:23588252 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Robo3 roundabout guidance receptor 3 affects expression
multiple interactions
ISO potassium bromate affects the expression of ROBO3 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of ROBO3 mRNA]
CTD PMID:27082013 NCBI chr 8:39,892,792...39,923,735
Ensembl chr 8:39,892,792...39,907,478
JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO potassium bromate results in increased expression of RPS27L mRNA CTD PMID:30559759 NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO potassium bromate results in increased expression of RRM2B mRNA CTD PMID:30559759 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP potassium bromate results in increased expression of S100A8 mRNA CTD PMID:23588252 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression EXP potassium bromate results in decreased expression of S100A9 mRNA CTD PMID:23588252 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP potassium bromate results in decreased expression of SCD1 mRNA CTD PMID:23588252 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO potassium bromate results in increased expression of SERTAD1 mRNA CTD PMID:30559759 NCBI chr 1:84,293,102...84,296,370
Ensembl chr 1:84,293,102...84,296,367
JBrowse link
G Sesn1 sestrin 1 increases expression ISO potassium bromate results in increased expression of SESN1 mRNA CTD PMID:30559759 NCBI chr20:46,667,116...46,758,306
Ensembl chr20:46,667,121...46,758,305
JBrowse link
G Sfn stratifin increases expression ISO potassium bromate results in increased expression of SFN mRNA CTD PMID:30008028, PMID:30559759 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Slc26a4 solute carrier family 26 member 4 decreases expression EXP potassium bromate results in decreased expression of SLC26A4 mRNA CTD PMID:23588252 NCBI chr 6:50,809,103...50,848,443
Ensembl chr 6:50,808,923...50,846,965
JBrowse link
G Slc26a7 solute carrier family 26 member 7 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of SLC26A7 mRNA] CTD PMID:27082013 NCBI chr 5:27,986,656...28,131,294
Ensembl chr 5:27,986,663...28,177,340
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO potassium bromate results in increased expression of SLC7A11 mRNA CTD PMID:30559759 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO potassium bromate results in increased expression of SLC7A5 mRNA CTD PMID:30008028 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 affects expression
multiple interactions
ISO potassium bromate affects the expression of SLCO2B1 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of SLCO2B1 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of SLCO2B1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of SLCO2B1 mRNA]
CTD PMID:27082013 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Sod1 superoxide dismutase 1 increases activity ISO potassium bromate results in increased activity of SOD1 protein CTD PMID:22012894 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO ceric oxide inhibits the reaction [potassium bromate results in increased expression of SOD2 mRNA] CTD PMID:25618551 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Spata22 spermatogenesis associated 22 decreases expression EXP potassium bromate results in decreased expression of SPATA22 mRNA CTD PMID:23588252 NCBI chr10:59,893,064...59,910,769
Ensembl chr10:59,879,850...59,911,051
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP
ISO
potassium bromate results in increased expression of SPP1 mRNA; potassium bromate results in increased expression of SPP1 protein CTD PMID:23588252, PMID:23811332, PMID:30008028 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO potassium bromate results in increased expression of SQSTM1 mRNA CTD PMID:30559759 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO potassium bromate results in increased expression of SRXN1 mRNA CTD PMID:22003191, PMID:30008028 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP potassium bromate results in increased expression of SULT2A1 mRNA CTD PMID:23588252 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO potassium bromate results in increased expression of TIGAR mRNA CTD PMID:30559759 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
G Tk1 thymidine kinase 1 increases mutagenesis ISO potassium bromate results in increased mutagenesis of TK1 gene CTD PMID:19853637 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tmem163 transmembrane protein 163 decreases expression EXP potassium bromate results in decreased expression of TMEM163 mRNA CTD PMID:23588252 NCBI chr13:44,166,306...44,345,735
Ensembl chr13:44,166,306...44,345,735
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO vanillin inhibits the reaction [potassium bromate results in increased expression of TNF mRNA] CTD PMID:26296324 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO potassium bromate results in increased expression of TNFSF9 mRNA CTD PMID:30559759 NCBI chr 9:9,909,942...9,912,276
Ensembl chr 9:9,909,948...9,912,276
JBrowse link
G Tns1 tensin 1 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of TNS1 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of TNS1 mRNA] CTD PMID:27082013 NCBI chr 9:81,190,192...81,401,020
Ensembl chr 9:81,194,119...81,400,987
JBrowse link
G Top3b DNA topoisomerase III beta decreases expression ISO potassium bromate results in decreased expression of TOP3B mRNA CTD PMID:22539617 NCBI chr11:88,346,305...88,374,896
Ensembl chr11:88,346,313...88,374,679
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases phosphorylation
ISO
EXP
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]; Ascorbic Acid inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein] CTD PMID:20067818, PMID:25015661 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases methylation
increases expression
ISO potassium bromate results in increased methylation of TP53INP1 promoter
potassium bromate results in increased expression of TP53INP1 mRNA
CTD PMID:30559759 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 increases expression ISO potassium bromate results in increased expression of TRIAP1 mRNA CTD PMID:30559759 NCBI chr12:46,987,404...46,989,906
Ensembl chr12:46,987,404...46,989,897
Ensembl chr12:46,987,404...46,989,897
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression EXP
ISO
potassium bromate results in increased expression of TRIB3 mRNA CTD PMID:23588252, PMID:30008028 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Ubd ubiquitin D increases expression EXP potassium bromate results in increased expression of UBD mRNA CTD PMID:23588252 NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
JBrowse link
G Vit vitrin multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of VIT mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of VIT mRNA] CTD PMID:27082013 NCBI chr 6:1,091,817...1,208,888
Ensembl chr 6:1,147,012...1,208,392
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 decreases expression ISO potassium bromate results in decreased expression of WARS1 mRNA CTD PMID:30559759 NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions
EXP potassium bromate results in increased activity of XDH protein
Taurine inhibits the reaction [potassium bromate results in increased activity of XDH protein]
CTD PMID:25213677 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 decreases expression ISO potassium bromate results in decreased expression of XRCC3 mRNA CTD PMID:22539617 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 multiple interactions
increases response to substance
ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AKR1B10 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AREG mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ATF3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CAR6 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CYP2D22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of FZD2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of GSTA5 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of HP mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of IL18R1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of KAT2B mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of MMP15 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PRG4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of SLCO2B1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of TNS1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CAR6 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CCL20 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CXCL3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of DSC1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of EGR4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of FRY mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of HCAR2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of HPGD mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LCN2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LGALS12 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NEBL mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NPR3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of OSTN mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of PLCH2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of SAA3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of SLC26A7 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of WFDC17 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AKR1B10 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AREG mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BLNK mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BMF mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of CYP2D22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of DUSP2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of EGR4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of FGL2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of GSTA5 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of HP mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IKZF2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IL18R1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of KLF15 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PRG4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PTPN22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of ROBO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of SLCO2B1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of VIT mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein; bisphenol A inhibits the reaction [[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein] CTD PMID:25693136, PMID:27082013 NCBI chr 7:123,259,881...123,280,613
Ensembl chr 7:123,259,761...123,280,612
JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO potassium bromate results in increased expression of ZMAT3 mRNA CTD PMID:30559759 NCBI chr 2:118,715,229...118,746,109
Ensembl chr 2:118,721,334...118,745,766
JBrowse link
sodium bromate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2 interleukin 2 multiple interactions ISO [sodium bromate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
sodium chlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 decreases expression EXP sodium chlorate results in decreased expression of BMP4 mRNA CTD PMID:12922982 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Cat catalase decreases activity EXP sodium chlorate results in decreased activity of CAT protein CTD PMID:28084674, PMID:30144278 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO sodium chlorate inhibits the reaction [CCL2 protein results in increased activity of CCR2 protein] CTD PMID:23408426 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
decreases sulfation
ISO sodium chlorate inhibits the reaction [CCL2 protein results in increased activity of CCR2 protein]
sodium chlorate results in decreased sulfation of CCR2 protein
CTD PMID:23408426
G Fbp1 fructose-bisphosphatase 1 decreases activity EXP sodium chlorate results in decreased activity of FBP1 protein CTD PMID:28084674 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fgf10 fibroblast growth factor 10 affects activity ISO sodium chlorate affects the activity of FGF10 protein CTD PMID:12818887 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fgf23 fibroblast growth factor 23 multiple interactions ISO sodium chlorate inhibits the reaction [FGF23 protein results in decreased uptake of Phosphates] CTD PMID:27432882 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP sodium chlorate inhibits the reaction [FSHB protein results in increased activity of PDE4A protein] CTD PMID:17261351 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP sodium chlorate results in decreased activity of G6PD protein CTD PMID:28084674 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity EXP sodium chlorate results in decreased activity of GSR protein CTD PMID:28084674, PMID:30144278 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Kl Klotho decreases expression ISO sodium chlorate results in decreased expression of KL protein CTD PMID:27432882 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions
ISO sodium chlorate results in decreased phosphorylation of MAPK1 protein
Heparin inhibits the reaction [sodium chlorate results in decreased phosphorylation of MAPK1 protein]
CTD PMID:19937756 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO Heparin inhibits the reaction [sodium chlorate results in decreased phosphorylation of MAPK3 protein] CTD PMID:19937756 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nanog Nanog homeobox increases expression ISO sodium chlorate results in increased expression of NANOG mRNA CTD PMID:19937756 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Pde4a phosphodiesterase 4A multiple interactions EXP sodium chlorate inhibits the reaction [FSHB protein results in increased activity of PDE4A protein] CTD PMID:17261351 NCBI chr 8:22,189,533...22,234,036
Ensembl chr 8:22,189,600...22,233,748
JBrowse link
G Sftpc surfactant protein C decreases expression EXP sodium chlorate results in decreased expression of SFTPC mRNA CTD PMID:12922982 NCBI chr15:52,211,538...52,214,480
Ensembl chr15:52,211,544...52,214,616
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] CTD PMID:12488351 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
sodium hypochlorite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Sodium Hypochlorite results in increased expression of ALPL mRNA CTD PMID:22083529 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Sodium Hypochlorite inhibits the reaction [bisphenol A binds to ESR2 protein]; Sodium Hypochlorite inhibits the reaction [Estradiol binds to ESR2 protein]; Sodium Hypochlorite inhibits the reaction [nonylphenol binds to ESR2 protein] CTD PMID:14723943 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Sodium Hypochlorite promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Sodium Hypochlorite promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile] CTD PMID:25614581 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
sodium perchlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of ALDH1L1 protein CTD PMID:30090431 NCBI chr 4:123,516,553...123,564,067
Ensembl chr 4:123,516,788...123,557,501
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of ALDH5A1 protein CTD PMID:30090431 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases expression EXP sodium perchlorate results in increased expression of CGA mRNA; sodium perchlorate results in increased expression of CGA protein CTD PMID:29139221 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Cth cystathionine gamma-lyase multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of CTH protein CTD PMID:30090431 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in decreased expression of CYB5A protein CTD PMID:30090431 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP sodium perchlorate results in decreased expression of DIO1 mRNA CTD PMID:29139221 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [sodium perchlorate results in increased abundance of perchlorate] which results in increased expression of FOS protein CTD PMID:30991129 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in decreased expression of FTCD protein CTD PMID:30090431 NCBI chr20:12,806,957...12,820,466
Ensembl chr20:12,806,957...12,820,466
JBrowse link
G Gamt guanidinoacetate N-methyltransferase multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of GAMT protein CTD PMID:30090431 NCBI chr 7:12,314,848...12,317,998
Ensembl chr 7:12,314,848...12,317,998
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
EXP sodium perchlorate results in increased expression of IFNG mRNA
sodium perchlorate results in increased expression of and results in increased secretion of IFNG protein
CTD PMID:29139221 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1a interleukin 1 alpha increases expression EXP sodium perchlorate results in increased expression of IL1A mRNA CTD PMID:29139221 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
EXP sodium perchlorate results in increased expression of and results in increased secretion of IL6 protein
sodium perchlorate results in increased expression of IL6 mRNA
CTD PMID:29139221 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Krt18 keratin 18 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of KRT18 protein CTD PMID:30090431 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Lep leptin multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in increased secretion of LEP protein CTD PMID:30090431 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased secretion of LHB protein CTD PMID:30090431 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Nkx2-1 NK2 homeobox 1 increases expression EXP sodium perchlorate results in increased expression of NKX2-1 protein CTD PMID:29139221 NCBI chr 6:77,418,096...77,423,383
Ensembl chr 6:77,418,096...77,421,286
JBrowse link
G Pax8 paired box 8 increases expression EXP sodium perchlorate results in increased expression of PAX8 protein CTD PMID:29139221 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Pon1 paraoxonase 1 multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON1 protein; [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of PON1 protein CTD PMID:30090431 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon2 paraoxonase 2 multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON2 protein CTD PMID:30090431 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
increases expression
decreases activity
ISO
EXP
sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Technetium]
sodium perchlorate results in increased expression of SLC5A5 mRNA; sodium perchlorate results in increased expression of SLC5A5 protein
sodium perchlorate results in decreased activity of SLC5A5 protein
CTD PMID:12488351, PMID:12489024, PMID:12541134, PMID:15221289, PMID:15520214, PMID:26827900, PMID:27979590, PMID:29139221 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
G Tg thyroglobulin increases expression EXP sodium perchlorate results in increased expression of TG protein CTD PMID:29139221 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
EXP sodium perchlorate results in increased expression of TNF mRNA
sodium perchlorate results in increased expression of and results in increased secretion of TNF protein
CTD PMID:29139221 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tpo thyroid peroxidase decreases activity
increases expression
EXP sodium perchlorate results in decreased activity of TPO protein
sodium perchlorate results in increased expression of TPO mRNA; sodium perchlorate results in increased expression of TPO protein
CTD PMID:23959146, PMID:29139221 NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
JBrowse link
G Trh thyrotropin releasing hormone decreases expression
increases expression
EXP sodium perchlorate results in decreased expression of TRH protein
sodium perchlorate results in increased expression of TRH mRNA
CTD PMID:29139221 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions
increases expression
ISO
EXP
sodium perchlorate inhibits the reaction [efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]]; sodium perchlorate inhibits the reaction [Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]]
[Iodine deficiency co-treated with sodium perchlorate] results in increased secretion of TSHB protein
sodium perchlorate results in increased expression of TSHB mRNA; sodium perchlorate results in increased expression of TSHB protein
CTD PMID:16030158, PMID:29139221, PMID:30090431 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression EXP sodium perchlorate results in increased expression of TSHR mRNA; sodium perchlorate results in increased expression of TSHR protein CTD PMID:29139221 NCBI chr 6:115,170,290...115,306,871
Ensembl chr 6:115,170,865...115,306,871
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      molecular entity 19784
        ion 15918
          inorganic ion 15692
            inorganic anion 11829
              halogen oxoanion 223
                bromine oxoanion + 169
                chlorine oxoanion + 64
                fluorine oxoanion + 0
                iodine oxoanion + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      p-block molecular entity 19672
                        chalcogen molecular entity 19362
                          oxygen molecular entity 19323
                            oxide 11578
                              oxoanion 8670
                                halogen oxoanion 223
                                  bromine oxoanion + 169
                                  chlorine oxoanion + 64
                                  fluorine oxoanion + 0
                                  iodine oxoanion + 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.