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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:halogen oxoanion
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Accession:CHEBI:33443 term browser browse the term
Synonyms:related_synonym: halogen oxoanions


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chlorite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity ISO chlorite results in increased activity of ACHE protein CTD PMID:27478981 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Cat catalase decreases activity ISO chlorite results in decreased activity of CAT protein CTD PMID:27478981 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO chlorite results in decreased activity of G6PD protein CTD PMID:27478981 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO chlorite results in decreased activity of GSR protein CTD PMID:27478981 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G H2ax H2A.X variant histone multiple interactions EXP chlorite promotes the reaction [Bromates results in increased phosphorylation of H2AX protein] CTD PMID:21864635 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Ldhb lactate dehydrogenase B increases activity ISO chlorite results in increased activity of LDHB protein CTD PMID:27478981 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403 		JBrowse link
G Sod1 superoxide dismutase 1 increases activity ISO chlorite results in increased activity of SOD1 protein CTD PMID:27478981 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity ISO chlorite results in decreased activity of TXNRD1 protein CTD PMID:27478981 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
perchlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 affects expression EXP perchlorate affects the expression of AQP1 mRNA CTD PMID:21623536 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression EXP perchlorate results in decreased expression of BDNF mRNA CTD PMID:35385113 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression EXP perchlorate results in decreased expression of BMP7 mRNA CTD PMID:35385113 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression EXP perchlorate results in decreased expression of CAMK4 mRNA CTD PMID:35385113 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO perchlorate results in decreased activity of CA1 protein CTD PMID:15664814 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO perchlorate results in decreased activity of CA2 protein CTD PMID:15664814 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car5a carbonic anhydrase 5A decreases activity ISO perchlorate results in decreased activity of CA5A protein CTD PMID:15664814 NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906 		JBrowse link
G Car9 carbonic anhydrase 9 decreases activity ISO perchlorate results in decreased activity of CA9 protein CTD PMID:15664814 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 EXP perchlorate results in increased activity of CASP3 protein
Sodium Iodide promotes the reaction [perchlorate results in increased activity of CASP3 protein]		 CTD PMID:11834455 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [sodium perchlorate results in increased abundance of perchlorate] which results in increased expression of FOS protein CTD PMID:30991129 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Mir133a1 microRNA 133a-1 multiple interactions ISO [Methimazole co-treated with perchlorate] results in increased expression of MIR133A1 mRNA CTD PMID:20808432 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir133b microRNA 133b multiple interactions ISO [Methimazole co-treated with perchlorate] results in increased expression of MIR133B mRNA CTD PMID:20808432 NCBI chr 9:23,098,134...23,098,217
Ensembl chr 9:23,098,134...23,098,217 		JBrowse link
G Mir135a microRNA 135a multiple interactions ISO [Methimazole co-treated with perchlorate] results in increased expression of MIR135A mRNA CTD PMID:20808432 NCBI chr 7:26,611,990...26,612,089
Ensembl chr 7:26,611,990...26,612,089 		JBrowse link
G Mir135b microRNA 135b multiple interactions ISO [Methimazole co-treated with perchlorate] results in increased expression of MIR135B mRNA CTD PMID:20808432 NCBI chr13:43,638,857...43,638,953
Ensembl chr13:43,638,857...43,638,953 		JBrowse link
G Mir148a microRNA 148a multiple interactions ISO [Methimazole co-treated with perchlorate] results in decreased expression of MIR148A mRNA CTD PMID:20808432 NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858 		JBrowse link
G Mir206 microRNA 206 multiple interactions ISO [Methimazole co-treated with perchlorate] results in increased expression of MIR206 mRNA CTD PMID:20808432 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332 		JBrowse link
G Papss1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 multiple interactions ISO perchlorate binds to and results in decreased activity of PAPSS1 protein CTD PMID:15065880 NCBI chr 2:220,040,343...220,114,399
Ensembl chr 2:220,040,312...220,114,395 		JBrowse link
G Pax8 paired box 8 decreases expression EXP perchlorate results in decreased expression of PAX8 mRNA CTD PMID:35385113 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 affects expression EXP perchlorate affects the expression of SLC22A3 mRNA CTD PMID:21623536 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 increases expression EXP perchlorate results in increased expression of SLC26A4 mRNA CTD PMID:35385113 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 increases expression
affects expression
decreases activity
multiple interactions		 ISO
EXP		 perchlorate results in increased expression of SLC5A5 protein
perchlorate results in increased expression of SLC5A5 mRNA
perchlorate affects the expression of SLC5A5 mRNA
perchlorate results in decreased activity of SLC5A5 protein
perchlorate inhibits the reaction [mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]]; perchlorate inhibits the reaction [SLC5A5 protein results in increased abundance of Sodium Iodide]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]		 CTD PMID:12601449 PMID:14633711 PMID:15347726 PMID:15850642 PMID:15941870 More... NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Tg thyroglobulin decreases expression ISO
EXP		 perchlorate results in decreased expression of TG protein
perchlorate results in decreased expression of TG mRNA		 CTD PMID:17332529 PMID:35385113 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Thrb thyroid hormone receptor beta decreases expression EXP perchlorate results in decreased expression of THRB mRNA CTD PMID:35385113 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tpo thyroid peroxidase increases expression EXP perchlorate results in increased expression of TPO mRNA CTD PMID:35385113 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta increases expression
multiple interactions		 ISO perchlorate results in increased expression of TSHB protein
[Iodides deficiency co-treated with perchlorate] results in increased expression of TSHB protein		 CTD PMID:17332529 PMID:20439182 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression EXP perchlorate results in decreased expression of TSHR mRNA CTD PMID:35385113 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538 		JBrowse link
potassium bromate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO potassium bromate results in decreased expression of A2M mRNA CTD PMID:30008028 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA] CTD PMID:27082013 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
affects expression		 ISO [potassium bromate co-treated with bisphenol A] affects the expression of AKR1B10 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AKR1B10 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AKR1B10 mRNA] CTD PMID:27082013 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression EXP potassium bromate results in increased expression of AKR1C2 mRNA CTD PMID:23588252 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions		 EXP potassium bromate results in increased phosphorylation of AKT1 protein
Squalene inhibits the reaction [potassium bromate results in increased phosphorylation of AKT1 protein]		 CTD PMID:33219891 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 decreases expression ISO potassium bromate results in decreased expression of AMIGO2 mRNA CTD PMID:30008028 NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695 		JBrowse link
G Anos1 anosmin 1 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of WFDC17 mRNA] CTD PMID:27082013 NCBI chr10:68,561,954...68,562,801
Ensembl chr10:68,561,954...68,562,801 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO potassium bromate results in increased expression of APEX1 mRNA CTD PMID:22539617 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G App amyloid beta precursor protein increases expression ISO potassium bromate results in increased expression of APP mRNA CTD PMID:30008028 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Areg amphiregulin multiple interactions
affects expression		 ISO [potassium bromate co-treated with bisphenol A] affects the expression of AREG mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AREG mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AREG mRNA] CTD PMID:27082013 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arg1 arginase 1 decreases expression ISO potassium bromate results in decreased expression of ARG1 mRNA CTD PMID:30008028 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) affects expression ISO potassium bromate affects the expression of ASNS mRNA CTD PMID:30008028 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions		 EXP
ISO		 potassium bromate results in increased expression of ATF3 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of ATF3 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ATF3 mRNA]		 CTD PMID:23588252 PMID:27082013 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO potassium bromate results in decreased expression of ATM mRNA CTD PMID:22539617 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression ISO potassium bromate results in decreased expression of ATP1B1 mRNA CTD PMID:30008028 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 decreases expression EXP potassium bromate results in decreased expression of ATP2B3 mRNA CTD PMID:23588252 NCBI chr  X:151,216,483...151,289,069
Ensembl chr  X:151,216,507...151,286,775 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression ISO potassium bromate results in decreased expression of BAAT mRNA CTD PMID:30008028 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO
EXP		 potassium bromate results in increased expression of BAX mRNA
Squalene promotes the reaction [potassium bromate results in increased expression of BAX protein]		 CTD PMID:30559759 PMID:33219891 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression ISO potassium bromate results in decreased expression of BBOX1 mRNA CTD PMID:30008028 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions		 EXP potassium bromate results in increased expression of BCL2 protein
Squalene inhibits the reaction [potassium bromate results in increased expression of BCL2 protein]		 CTD PMID:33219891 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Blnk B-cell linker affects expression
multiple interactions		 ISO potassium bromate affects the expression of BLNK mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BLNK mRNA]		 CTD PMID:27082013 NCBI chr 1:239,753,640...239,821,113
Ensembl chr 1:239,753,648...239,821,113 		JBrowse link
G Bmf Bcl2 modifying factor affects expression
multiple interactions		 ISO potassium bromate affects the expression of BMF mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BMF mRNA]		 CTD PMID:27082013 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO potassium bromate results in increased expression of BRCA1 mRNA CTD PMID:22539617 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Car3 carbonic anhydrase 3 decreases expression EXP potassium bromate results in decreased expression of CA3 mRNA CTD PMID:23588252 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Car6 carbonic anhydrase 6 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of CAR6 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CAR6 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CAR6 mRNA] CTD PMID:27082013 NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644 		JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 decreases expression ISO potassium bromate results in decreased expression of CARS1 mRNA CTD PMID:30559759 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions		 EXP potassium bromate results in increased expression of CASP3 protein
Squalene promotes the reaction [potassium bromate results in increased expression of CASP3 protein]		 CTD PMID:33219891 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase decreases activity
multiple interactions
increases activity		 ISO
EXP		 potassium bromate results in decreased activity of CAT protein
vanillin inhibits the reaction [potassium bromate results in increased activity of CAT protein]
Arbutin inhibits the reaction [potassium bromate results in decreased activity of CAT protein]; Squalene inhibits the reaction [potassium bromate results in decreased activity of CAT protein]; Taurine inhibits the reaction [potassium bromate results in decreased activity of CAT protein]		 CTD PMID:22012894 PMID:25213677 PMID:26296324 PMID:27074584 PMID:33219891 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions		 EXP
ISO		 potassium bromate results in increased expression of CCL20 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CCL20 mRNA]		 CTD PMID:23588252 PMID:27082013 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions
increases expression		 ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased expression of CCNB1 protein] CTD PMID:20067818 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccno cyclin O decreases expression ISO potassium bromate results in decreased expression of CCNO mRNA CTD PMID:22539617 NCBI chr 2:44,630,873...44,633,912
Ensembl chr 2:44,626,369...44,633,914 		JBrowse link
G Cdhr1 cadherin-related family member 1 increases expression EXP potassium bromate results in increased expression of CDHR1 mRNA CTD PMID:23588252 NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases phosphorylation ISO potassium bromate results in increased phosphorylation of CDK1 protein CTD PMID:20067818 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
affects methylation
affects expression
multiple interactions		 ISO
EXP		 potassium bromate results in increased expression of CDKN1A mRNA; potassium bromate results in increased expression of CDKN1A protein
potassium bromate affects the methylation of CDKN1A gene
potassium bromate affects the expression of CDKN1A mRNA; potassium bromate affects the expression of CDKN1A protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; Azacitidine inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; trichostatin A inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]		 CTD PMID:20067818 PMID:23588252 PMID:23811332 PMID:25015661 PMID:30008028 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cfd complement factor D decreases expression EXP potassium bromate results in decreased expression of CFD mRNA CTD PMID:23588252 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression EXP potassium bromate results in increased expression of CHAC1 mRNA CTD PMID:23588252 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Cldn2 claudin 2 decreases expression ISO potassium bromate results in decreased expression of CLDN2 mRNA CTD PMID:30008028 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Clu clusterin increases expression EXP potassium bromate results in increased expression of CLU protein CTD PMID:23159986 PMID:23588252 PMID:23811332 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Coch cochlin decreases expression EXP potassium bromate results in decreased expression of COCH mRNA CTD PMID:23588252 NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109 		JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP potassium bromate results in increased expression of COMT mRNA CTD PMID:23588252 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression EXP potassium bromate results in increased expression of CSRP3 mRNA CTD PMID:23588252 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Cth cystathionine gamma-lyase increases methylation ISO potassium bromate results in increased methylation of CTH promoter CTD PMID:30559759 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CXCL3 mRNA] CTD PMID:27082013 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 decreases expression
increases expression		 EXP potassium bromate results in decreased expression of CYP2C7 mRNA
potassium bromate results in increased expression of CYP2C7 mRNA		 CTD PMID:23588252 NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
affects expression		 ISO [potassium bromate co-treated with bisphenol A] affects the expression of CYP2D22 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CYP2D22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of CYP2D22 mRNA] CTD PMID:27082013 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression ISO potassium bromate results in decreased expression of CYP3A4 mRNA CTD PMID:30008028 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO potassium bromate results in increased expression of DDB2 mRNA CTD PMID:30559759 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO potassium bromate results in increased expression of DDIT3 mRNA CTD PMID:30008028 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dio3 iodothyronine deiodinase 3 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA] CTD PMID:27082013 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Dsc1 desmocollin 1 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of DSC1 mRNA] CTD PMID:27082013 NCBI chr18:11,499,936...11,556,801
Ensembl chr18:11,502,003...11,528,494 		JBrowse link
G Dusp2 dual specificity phosphatase 2 affects expression
multiple interactions		 ISO potassium bromate affects the expression of DUSP2 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of DUSP2 mRNA]		 CTD PMID:27082013 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499 		JBrowse link
G Egr4 early growth response 4 multiple interactions
affects expression		 ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of EGR4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of EGR4 mRNA] CTD PMID:27082013 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit decreases expression ISO potassium bromate results in decreased expression of ERCC4 mRNA CTD PMID:22539617 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor affects response to substance
multiple interactions		 ISO ERCC6 protein affects the susceptibility to potassium bromate
veliparib promotes the reaction [ERCC6 protein affects the susceptibility to potassium bromate]		 CTD PMID:25136123 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ereg epiregulin increases expression ISO potassium bromate results in increased expression of EREG mRNA CTD PMID:30008028 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO potassium bromate results in increased expression of FAS mRNA CTD PMID:30559759 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO potassium bromate results in increased expression of FBXO22 mRNA CTD PMID:30559759 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO potassium bromate results in decreased expression of FEN1 mRNA CTD PMID:22539617 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fgb fibrinogen beta chain increases expression EXP potassium bromate results in increased expression of FGB mRNA CTD PMID:23588252 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgl2 fibrinogen-like 2 affects expression
multiple interactions		 ISO potassium bromate affects the expression of FGL2 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of FGL2 mRNA]		 CTD PMID:27082013 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207 		JBrowse link
G Fry FRY microtubule binding protein multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of FRY mRNA] CTD PMID:27082013 NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116 		JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO potassium bromate results in increased expression of FTH1 mRNA CTD PMID:30559759 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Fzd2 frizzled class receptor 2 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of FZD2 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of FZD2 mRNA] CTD PMID:27082013 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
decreases activity		 EXP Taurine inhibits the reaction [potassium bromate results in decreased activity of G6PD protein] CTD PMID:25213677 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO potassium bromate results in increased expression of GADD45A mRNA CTD PMID:30008028 PMID:30559759 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
increases methylation		 ISO potassium bromate results in increased expression of GCLM mRNA
potassium bromate results in increased methylation of GCLM promoter		 CTD PMID:30008028 PMID:30559759 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO potassium bromate results in increased expression of GCNT3 mRNA CTD PMID:30559759 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562 		JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO potassium bromate results in increased expression of GPR87 mRNA CTD PMID:30559759 NCBI chr 2:143,439,741...143,440,901
Ensembl chr 2:143,439,735...143,458,190 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions		 EXP potassium bromate results in increased activity of GPT protein
Squalene inhibits the reaction [potassium bromate results in increased activity of GPT protein]		 CTD PMID:33219891 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Grifin galectin-related inter-fiber protein decreases expression EXP potassium bromate results in decreased expression of GRIFIN mRNA CTD PMID:23588252 NCBI chr12:14,080,170...14,082,892
Ensembl chr12:14,080,910...14,082,877 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions		 ISO
EXP		 potassium bromate results in decreased activity of GSR protein
Squalene inhibits the reaction [potassium bromate results in decreased activity of GSR protein]; Taurine inhibits the reaction [potassium bromate results in decreased activity of GSR protein]		 CTD PMID:22012894 PMID:25213677 PMID:33219891 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 affects expression
multiple interactions		 ISO potassium bromate affects the expression of GSTA5 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of GSTA5 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of GSTA5 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of GSTA5 mRNA]		 CTD PMID:27082013 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation		 ISO
EXP		 [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein; bisphenol A inhibits the reaction [[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein]
potassium bromate results in increased phosphorylation of H2AX protein
Azacitidine inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]; trichostatin A inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]		 CTD PMID:25015661 PMID:25693136 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression EXP potassium bromate results in increased expression of HAVCR1 mRNA; potassium bromate results in increased expression of HAVCR1 protein CTD PMID:23588252 PMID:23811332 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO ceric oxide inhibits the reaction [potassium bromate results in increased expression of HMOX1 mRNA] CTD PMID:25618551 PMID:30008028 PMID:30559759 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression
decreases expression		 ISO potassium bromate results in increased expression of HNF4A mRNA
potassium bromate results in decreased expression of HNF4A mRNA		 CTD PMID:30008028 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hp haptoglobin affects expression
multiple interactions		 ISO potassium bromate affects the expression of HP mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of HP mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of HP mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of HP mRNA]		 CTD PMID:27082013 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of HPGD mRNA] CTD PMID:27082013 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis ISO potassium bromate results in increased mutagenesis of HPRT1 gene CTD PMID:19853637 PMID:22539617 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP potassium bromate results in increased expression of IGFBP1 mRNA CTD PMID:23588252 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Ikzf2 IKAROS family zinc finger 2 affects expression
multiple interactions		 ISO potassium bromate affects the expression of IKZF2 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IKZF2 mRNA]		 CTD PMID:27082013 NCBI chr 9:71,046,038...71,191,296
Ensembl chr 9:71,042,440...71,190,867 		JBrowse link
G Il18r1 interleukin 18 receptor 1 affects expression
multiple interactions		 ISO potassium bromate affects the expression of IL18R1 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of IL18R1 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of IL18R1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IL18R1 mRNA]		 CTD PMID:27082013 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 EXP
ISO		 potassium bromate results in increased expression of IL1B mRNA
vanillin inhibits the reaction [potassium bromate results in increased expression of IL1B mRNA]		 CTD PMID:23588252 PMID:26296324 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il24 interleukin 24 increases expression EXP potassium bromate results in increased expression of IL24 mRNA CTD PMID:23588252 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 ISO potassium bromate results in increased expression of IL6 mRNA
vanillin inhibits the reaction [potassium bromate results in increased expression of IL6 mRNA]		 CTD PMID:26296324 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kat2b lysine acetyltransferase 2B multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of KAT2B mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of KAT2B mRNA] CTD PMID:27082013 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Kirrel3 kirre like nephrin family adhesion molecule 3 decreases expression EXP potassium bromate results in decreased expression of KIRREL3 mRNA CTD PMID:23588252 NCBI chr 8:32,865,779...33,407,555
Ensembl chr 8:32,862,776...33,405,676 		JBrowse link
G Klf15 KLF transcription factor 15 affects expression
multiple interactions		 ISO potassium bromate affects the expression of KLF15 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of KLF15 mRNA]		 CTD PMID:27082013 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LCN2 mRNA] CTD PMID:27082013 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lgals12 galectin 12 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LGALS12 mRNA] CTD PMID:27082013 NCBI chr 1:204,832,065...204,842,759
Ensembl chr 1:204,832,065...204,842,759 		JBrowse link
G Lig3 DNA ligase 3 decreases expression ISO potassium bromate results in decreased expression of LIG3 mRNA CTD PMID:22539617 NCBI chr10:67,717,808...67,741,141
Ensembl chr10:67,717,812...67,798,414 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO potassium bromate results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:20067818 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO potassium bromate results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:20067818 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO potassium bromate results in increased expression of MDM2 mRNA CTD PMID:30559759 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Me1 malic enzyme 1 increases expression ISO potassium bromate results in increased expression of ME1 mRNA CTD PMID:30008028 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Med1 mediator complex subunit 1 decreases phosphorylation ISO potassium bromate results in decreased phosphorylation of MED1 protein CTD PMID:25068892 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Mir126b microRNA 126b decreases expression ISO potassium bromate results in decreased expression of MIR126 mRNA CTD PMID:30559759 NCBI chr 3:9,415,087...9,415,159 JBrowse link
G Mir134 microRNA 134 increases expression ISO potassium bromate results in increased expression of MIR134 mRNA CTD PMID:30559759 NCBI chr 6:128,748,908...128,748,980 JBrowse link
G Mir137 microRNA 137 decreases expression ISO potassium bromate results in decreased expression of MIR137 mRNA CTD PMID:30559759 NCBI chr 2:206,480,881...206,480,982
Ensembl chr 2:206,480,884...206,480,985 		JBrowse link
G Mir146b microRNA 146b decreases expression ISO potassium bromate results in decreased expression of MIR146B mRNA CTD PMID:30559759 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525 		JBrowse link
G Mir193a microRNA 193a decreases expression ISO potassium bromate results in decreased expression of MIR193A mRNA CTD PMID:30559759 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir193b microRNA 193b decreases expression ISO potassium bromate results in decreased expression of MIR193B mRNA CTD PMID:30559759 NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,317,742...1,317,824 		JBrowse link
G Mir205 microRNA 205 decreases expression ISO potassium bromate results in decreased expression of MIR205 mRNA CTD PMID:30559759 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985 		JBrowse link
G Mir21 microRNA 21 increases expression ISO potassium bromate results in increased expression of MIR21 mRNA CTD PMID:30559759 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir23b microRNA 23b decreases expression ISO potassium bromate results in decreased expression of MIR23B mRNA CTD PMID:30559759 NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763 		JBrowse link
G Mir29b1 microRNA 29b-1 decreases expression ISO potassium bromate results in decreased expression of MIR29B1 mRNA CTD PMID:30559759 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir322 microRNA 322 decreases expression ISO potassium bromate results in decreased expression of MIR424 mRNA CTD PMID:30559759 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688 		JBrowse link
G Mir331 microRNA 331 decreases expression ISO potassium bromate results in decreased expression of MIR331 mRNA CTD PMID:30559759 NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485 		JBrowse link
G Mir542 microRNA 542 decreases expression ISO potassium bromate results in decreased expression of MIR542 mRNA CTD PMID:30559759 NCBI chr  X:132,802,623...132,802,701
Ensembl chr  X:132,802,623...132,802,701 		JBrowse link
G Mmp15 matrix metallopeptidase 15 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of MMP15 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of MMP15 mRNA] CTD PMID:27082013 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
multiple interactions		 EXP potassium bromate results in increased expression of MMP2 protein
Squalene inhibits the reaction [potassium bromate results in increased expression of MMP2 protein]		 CTD PMID:33219891 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression		 ISO vanillin inhibits the reaction [potassium bromate results in increased expression of MT2 mRNA] CTD PMID:27074584 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression EXP potassium bromate results in increased expression of MTHFD2 mRNA CTD PMID:23588252 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression ISO potassium bromate results in decreased expression of MUC1 mRNA CTD PMID:30008028 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Mutyh mutY DNA glycosylase decreases expression ISO potassium bromate results in decreased expression of MUTYH mRNA CTD PMID:22539617 NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146 		JBrowse link
G Myh1 myosin heavy chain 1 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH1 mRNA] CTD PMID:27082013 NCBI chr10:51,885,913...51,909,699
Ensembl chr10:51,885,913...51,946,295 		JBrowse link
G Myh2 myosin heavy chain 2 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH2 mRNA] CTD PMID:27082013 NCBI chr10:51,856,738...51,883,236
Ensembl chr10:51,856,738...51,883,236 		JBrowse link
G Mylk3 myosin light chain kinase 3 decreases expression EXP potassium bromate results in decreased expression of MYLK3 mRNA CTD PMID:23588252 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954 		JBrowse link
G Nebl nebulette multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NEBL mRNA] CTD PMID:27082013 NCBI chr17:80,113,891...80,466,331
Ensembl chr17:80,118,543...80,466,210 		JBrowse link
G Npr3 natriuretic peptide receptor 3 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NPR3 mRNA] CTD PMID:27082013 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO potassium bromate results in increased expression of NQO1 mRNA CTD PMID:30559759 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases response to substance
increases response to substance		 ISO OGG1 gene mutant form results in decreased susceptibility to potassium bromate
OGG1 protein results in increased susceptibility to potassium bromate		 CTD PMID:25693136 PMID:34196753 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Ostn osteocrin multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of OSTN mRNA] CTD PMID:27082013 NCBI chr11:73,442,167...73,478,498
Ensembl chr11:73,442,487...73,468,603 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO potassium bromate results in decreased expression of PHGDH mRNA CTD PMID:30559759 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Plch2 phospholipase C, eta 2 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of PLCH2 mRNA] CTD PMID:27082013 NCBI chr 5:165,544,209...165,613,769
Ensembl chr 5:165,544,200...165,602,356 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase decreases expression ISO potassium bromate results in decreased expression of PNKP mRNA CTD PMID:22539617 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO potassium bromate results in increased expression of PPM1D mRNA CTD PMID:30559759 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases methylation ISO potassium bromate results in decreased methylation of PPP1R15A promoter CTD PMID:30559759 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Prg4 proteoglycan 4 affects expression
multiple interactions		 ISO potassium bromate affects the expression of PRG4 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of PRG4 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PRG4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PRG4 mRNA]		 CTD PMID:27082013 NCBI chr13:62,487,257...62,504,657
Ensembl chr13:62,487,257...62,504,119 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 ISO potassium bromate results in increased expression of PTGS2 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA]; vanillin inhibits the reaction [potassium bromate results in increased expression of PTGS2 mRNA]		 CTD PMID:26296324 PMID:27082013 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 affects expression
multiple interactions		 ISO potassium bromate affects the expression of PTPN22 mRNA
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PTPN22 mRNA]		 CTD PMID:27082013 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Rab3gap2 RAB3 GTPase activating non-catalytic protein subunit 2 increases expression EXP potassium bromate results in increased expression of RAB3GAP2 mRNA CTD PMID:23588252 NCBI chr13:96,757,430...96,828,930
Ensembl chr13:96,757,460...96,829,478 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression		 EXP Squalene inhibits the reaction [potassium bromate results in increased expression of RELA protein] CTD PMID:33219891 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ren renin increases expression EXP potassium bromate results in increased expression of REN1 mRNA CTD PMID:23588252 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Retn resistin decreases expression EXP potassium bromate results in decreased expression of RETN mRNA CTD PMID:23588252 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Robo3 roundabout guidance receptor 3 affects expression
multiple interactions		 ISO potassium bromate affects the expression of ROBO3 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of ROBO3 mRNA]		 CTD PMID:27082013 NCBI chr 8:37,133,542...37,151,674
Ensembl chr 8:37,133,916...37,151,315 		JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO potassium bromate results in increased expression of RPS27L mRNA CTD PMID:30559759 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO potassium bromate results in increased expression of RRM2B mRNA CTD PMID:30559759 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP potassium bromate results in increased expression of S100A8 mRNA CTD PMID:23588252 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression EXP potassium bromate results in decreased expression of S100A9 mRNA CTD PMID:23588252 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP potassium bromate results in decreased expression of SCD1 mRNA CTD PMID:23588252 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO potassium bromate results in increased expression of SERTAD1 mRNA CTD PMID:30559759 NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091 		JBrowse link
G Sesn1 sestrin 1 increases expression ISO potassium bromate results in increased expression of SESN1 mRNA CTD PMID:30559759 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sfn stratifin increases expression ISO potassium bromate results in increased expression of SFN mRNA CTD PMID:30008028 PMID:30559759 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 decreases expression EXP potassium bromate results in decreased expression of SLC26A4 mRNA CTD PMID:23588252 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703 		JBrowse link
G Slc26a7 solute carrier family 26 member 7 multiple interactions ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of SLC26A7 mRNA] CTD PMID:27082013 NCBI chr 5:27,884,400...28,021,865
Ensembl chr 5:27,887,042...28,021,658 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO potassium bromate results in increased expression of SLC7A11 mRNA CTD PMID:30559759 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO potassium bromate results in increased expression of SLC7A5 mRNA CTD PMID:30008028 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 affects expression
multiple interactions		 ISO potassium bromate affects the expression of SLCO2B1 mRNA
[potassium bromate co-treated with bisphenol A] affects the expression of SLCO2B1 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of SLCO2B1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of SLCO2B1 mRNA]		 CTD PMID:27082013 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Sod1 superoxide dismutase 1 increases activity
decreases activity
multiple interactions		 ISO
EXP		 potassium bromate results in increased activity of SOD1 protein
potassium bromate results in decreased activity of SOD1 protein
Arbutin inhibits the reaction [potassium bromate results in decreased activity of SOD1 protein]		 CTD PMID:22012894 PMID:36284482 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression		 ISO ceric oxide inhibits the reaction [potassium bromate results in increased expression of SOD2 mRNA] CTD PMID:25618551 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Spata22 spermatogenesis associated 22 decreases expression EXP potassium bromate results in decreased expression of SPATA22 mRNA CTD PMID:23588252 NCBI chr10:57,945,272...57,963,081
Ensembl chr10:57,932,187...57,963,081 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP
ISO		 potassium bromate results in increased expression of SPP1 mRNA; potassium bromate results in increased expression of SPP1 protein CTD PMID:23588252 PMID:23811332 PMID:30008028 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO potassium bromate results in increased expression of SQSTM1 mRNA CTD PMID:30559759 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO potassium bromate results in increased expression of SRXN1 mRNA CTD PMID:22003191 PMID:30008028 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP potassium bromate results in increased expression of SULT2A1 mRNA CTD PMID:23588252 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO potassium bromate results in increased expression of TIGAR mRNA CTD PMID:30559759 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
G Tk1 thymidine kinase 1 increases mutagenesis ISO potassium bromate results in increased mutagenesis of TK1 gene CTD PMID:19853637 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tmem163 transmembrane protein 163 decreases expression EXP potassium bromate results in decreased expression of TMEM163 mRNA CTD PMID:23588252 NCBI chr13:38,967,913...39,141,664
Ensembl chr13:38,968,101...39,141,452 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO vanillin inhibits the reaction [potassium bromate results in increased expression of TNF mRNA] CTD PMID:26296324 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO potassium bromate results in increased expression of TNFSF9 mRNA CTD PMID:30559759 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345 		JBrowse link
G Tns1 tensin 1 multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of TNS1 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of TNS1 mRNA] CTD PMID:27082013 NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225 		JBrowse link
G Top3b DNA topoisomerase III beta decreases expression ISO potassium bromate results in decreased expression of TOP3B mRNA CTD PMID:22539617 NCBI chr11:84,097,018...84,125,474
Ensembl chr11:84,097,026...84,125,392 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases phosphorylation		 ISO
EXP		 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]; Ascorbic Acid inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein] CTD PMID:20067818 PMID:25015661 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases methylation
increases expression		 ISO potassium bromate results in increased methylation of TP53INP1 promoter
potassium bromate results in increased expression of TP53INP1 mRNA		 CTD PMID:30559759 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 increases expression ISO potassium bromate results in increased expression of TRIAP1 mRNA CTD PMID:30559759 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression EXP
ISO		 potassium bromate results in increased expression of TRIB3 mRNA CTD PMID:23588252 PMID:30008028 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Ubd ubiquitin D increases expression EXP potassium bromate results in increased expression of UBD mRNA CTD PMID:23588252 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression		 EXP Squalene inhibits the reaction [potassium bromate results in increased expression of VEGFA protein] CTD PMID:33219891 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vit vitrin multiple interactions ISO [potassium bromate co-treated with bisphenol A] affects the expression of VIT mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of VIT mRNA] CTD PMID:27082013 NCBI chr 6:16,445,966...16,565,644
Ensembl chr 6:16,445,955...16,565,665 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 decreases expression ISO potassium bromate results in decreased expression of WARS1 mRNA CTD PMID:30559759 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269 		JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions		 EXP potassium bromate results in increased activity of XDH protein
Taurine inhibits the reaction [potassium bromate results in increased activity of XDH protein]		 CTD PMID:25213677 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 decreases expression ISO potassium bromate results in decreased expression of XRCC3 mRNA CTD PMID:22539617 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 multiple interactions
increases response to substance		 ISO [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AKR1B10 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AREG mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ATF3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CAR6 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CYP2D22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of FZD2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of GSTA5 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of HP mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of IL18R1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of KAT2B mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of MMP15 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PRG4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of SLCO2B1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of TNS1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CAR6 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CCL20 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CXCL3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of DSC1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of EGR4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of FRY mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of HCAR2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of HPGD mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LCN2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LGALS12 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NEBL mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NPR3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of OSTN mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of PLCH2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of SAA3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of SLC26A7 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of WFDC17 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AKR1B10 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AREG mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BLNK mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BMF mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of CYP2D22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of DUSP2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of EGR4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of FGL2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of GSTA5 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of HP mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IKZF2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IL18R1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of KLF15 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PRG4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PTPN22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of ROBO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of SLCO2B1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of VIT mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein; bisphenol A inhibits the reaction [[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein] CTD PMID:25693136 PMID:27082013 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO potassium bromate results in increased expression of ZMAT3 mRNA CTD PMID:30559759 NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:115,106,966...115,136,863 		JBrowse link
sodium bromate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2 interleukin 2 multiple interactions ISO [sodium bromate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
sodium chlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 decreases expression EXP sodium chlorate results in decreased expression of BMP4 mRNA CTD PMID:12922982 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Cat catalase decreases activity EXP sodium chlorate results in decreased activity of CAT protein CTD PMID:28084674 PMID:30144278 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO sodium chlorate inhibits the reaction [CCL2 protein results in increased activity of CCR2 protein] CTD PMID:23408426 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
decreases sulfation		 ISO sodium chlorate inhibits the reaction [CCL2 protein results in increased activity of CCR2 protein]
sodium chlorate results in decreased sulfation of CCR2 protein		 CTD PMID:23408426 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 decreases activity EXP sodium chlorate results in decreased activity of FBP1 protein CTD PMID:28084674 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fgf10 fibroblast growth factor 10 affects activity ISO sodium chlorate affects the activity of FGF10 protein CTD PMID:12818887 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf23 fibroblast growth factor 23 multiple interactions ISO sodium chlorate inhibits the reaction [FGF23 protein results in decreased uptake of Phosphates] CTD PMID:27432882 NCBI chr 4:159,914,267...159,923,821
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP sodium chlorate inhibits the reaction [FSHB protein results in increased activity of PDE4A protein] CTD PMID:17261351 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP sodium chlorate results in decreased activity of G6PD protein CTD PMID:28084674 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity EXP sodium chlorate results in decreased activity of GSR protein CTD PMID:28084674 PMID:30144278 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Kl Klotho decreases expression ISO sodium chlorate results in decreased expression of KL protein CTD PMID:27432882 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions		 ISO sodium chlorate results in decreased phosphorylation of MAPK1 protein
Heparin inhibits the reaction [sodium chlorate results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:19937756 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation		 ISO Heparin inhibits the reaction [sodium chlorate results in decreased phosphorylation of MAPK3 protein] CTD PMID:19937756 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nanog Nanog homeobox increases expression ISO sodium chlorate results in increased expression of NANOG mRNA CTD PMID:19937756 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Pde4a phosphodiesterase 4A multiple interactions EXP sodium chlorate inhibits the reaction [FSHB protein results in increased activity of PDE4A protein] CTD PMID:17261351 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Sftpc surfactant protein C decreases expression EXP sodium chlorate results in decreased expression of SFTPC mRNA CTD PMID:12922982 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] CTD PMID:12488351 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
sodium hypochlorite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Sodium Hypochlorite results in increased expression of ALPL mRNA CTD PMID:22083529 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Sodium Hypochlorite inhibits the reaction [bisphenol A binds to ESR2 protein]; Sodium Hypochlorite inhibits the reaction [Estradiol binds to ESR2 protein]; Sodium Hypochlorite inhibits the reaction [nonylphenol binds to ESR2 protein] CTD PMID:14723943 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Sodium Hypochlorite promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Sodium Hypochlorite promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile] CTD PMID:25614581 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
sodium perchlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of ALDH1L1 protein CTD PMID:30090431 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of ALDH5A1 protein CTD PMID:30090431 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases expression EXP sodium perchlorate results in increased expression of CGA mRNA; sodium perchlorate results in increased expression of CGA protein CTD PMID:29139221 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191 		JBrowse link
G Cth cystathionine gamma-lyase multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of CTH protein CTD PMID:30090431 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in decreased expression of CYB5A protein CTD PMID:30090431 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP sodium perchlorate results in decreased expression of DIO1 mRNA CTD PMID:29139221 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [sodium perchlorate results in increased abundance of perchlorate] which results in increased expression of FOS protein CTD PMID:30991129 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in decreased expression of FTCD protein CTD PMID:30090431 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of GAMT protein CTD PMID:30090431 NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778 		JBrowse link
G Ifng interferon gamma increases expression
multiple interactions		 EXP sodium perchlorate results in increased expression of IFNG mRNA
sodium perchlorate results in increased expression of and results in increased secretion of IFNG protein		 CTD PMID:29139221 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1a interleukin 1 alpha increases expression EXP sodium perchlorate results in increased expression of IL1A mRNA CTD PMID:29139221 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 EXP sodium perchlorate results in increased expression of and results in increased secretion of IL6 protein
sodium perchlorate results in increased expression of IL6 mRNA		 CTD PMID:29139221 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Krt18 keratin 18 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of KRT18 protein CTD PMID:30090431 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Lep leptin multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in increased secretion of LEP protein CTD PMID:30090431 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased secretion of LHB protein CTD PMID:30090431 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Nkx2-1 NK2 homeobox 1 increases expression EXP sodium perchlorate results in increased expression of NKX2-1 protein CTD PMID:29139221 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Pax8 paired box 8 increases expression EXP sodium perchlorate results in increased expression of PAX8 protein CTD PMID:29139221 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Pon1 paraoxonase 1 multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON1 protein; [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of PON1 protein CTD PMID:30090431 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Pon2 paraoxonase 2 multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON2 protein CTD PMID:30090431 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
increases expression
decreases activity		 ISO
EXP		 sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Technetium]
sodium perchlorate results in increased expression of SLC5A5 mRNA; sodium perchlorate results in increased expression of SLC5A5 protein
sodium perchlorate results in decreased activity of SLC5A5 protein		 CTD PMID:12488351 PMID:12489024 PMID:12541134 PMID:15221289 PMID:15520214 More... NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Tg thyroglobulin increases expression EXP sodium perchlorate results in increased expression of TG protein CTD PMID:29139221 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions		 EXP sodium perchlorate results in increased expression of TNF mRNA
sodium perchlorate results in increased expression of and results in increased secretion of TNF protein		 CTD PMID:29139221 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tpo thyroid peroxidase decreases activity
increases expression		 EXP sodium perchlorate results in decreased activity of TPO protein
sodium perchlorate results in increased expression of TPO mRNA; sodium perchlorate results in increased expression of TPO protein		 CTD PMID:23959146 PMID:29139221 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Trh thyrotropin releasing hormone decreases expression
increases expression		 EXP sodium perchlorate results in decreased expression of TRH protein
sodium perchlorate results in increased expression of TRH mRNA		 CTD PMID:29139221 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions
increases expression		 ISO
EXP		 sodium perchlorate inhibits the reaction [efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]]; sodium perchlorate inhibits the reaction [Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]]
[Iodine deficiency co-treated with sodium perchlorate] results in increased secretion of TSHB protein
sodium perchlorate results in increased expression of TSHB mRNA; sodium perchlorate results in increased expression of TSHB protein		 CTD PMID:16030158 PMID:29139221 PMID:30090431 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression EXP sodium perchlorate results in increased expression of TSHR mRNA; sodium perchlorate results in increased expression of TSHR protein CTD PMID:29139221 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    chemical entity 19919
      molecular entity 19919
        ion 16531
          inorganic ion 16162
            inorganic anion 12660
              halogen oxoanion 233
                bromine oxoanion + 176
                chlorine oxoanion + 69
                fluorine oxoanion + 0
                iodine oxoanion + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19867
                    main group molecular entity 19867
                      p-block molecular entity 19867
                        chalcogen molecular entity 19616
                          oxygen molecular entity 19589
                            oxide 12759
                              oxoanion 10303
                                halogen oxoanion 233
                                  bromine oxoanion + 176
                                  chlorine oxoanion + 69
                                  fluorine oxoanion + 0
                                  iodine oxoanion + 0
paths to the root