Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chlorine oxoanion
go back to main search page
Accession:CHEBI:33437 term browser browse the term
Synonyms:related_synonym: chlorine oxoanions
 cyclic_relationship: is_conjugate_base_of CHEBI:33426



show annotations for term's descendants           Sort by:
chlorite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity ISO chlorite results in increased activity of ACHE protein CTD PMID:27478981 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Cat catalase decreases activity ISO chlorite results in decreased activity of CAT protein CTD PMID:27478981 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases activity ISO chlorite results in decreased activity of G6PD protein CTD PMID:27478981 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Gsr glutathione reductase decreases activity ISO chlorite results in decreased activity of GSR protein CTD PMID:27478981 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO chlorite promotes the reaction [Bromates results in increased phosphorylation of H2AX protein] CTD PMID:21864635 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
JBrowse link
G Ldhb lactate dehydrogenase B increases activity ISO chlorite results in increased activity of LDHB protein CTD PMID:27478981 NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
JBrowse link
G Sod1 superoxide dismutase 1, soluble increases activity ISO chlorite results in increased activity of SOD1 protein CTD PMID:27478981 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity ISO chlorite results in decreased activity of TXNRD1 protein CTD PMID:27478981 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
JBrowse link
perchlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 affects expression ISO perchlorate affects the expression of AQP1 mRNA CTD PMID:21623536 NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
JBrowse link
G Bdnf brain derived neurotrophic factor decreases expression ISO perchlorate results in decreased expression of BDNF mRNA CTD PMID:35385113 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression ISO perchlorate results in decreased expression of BMP7 mRNA CTD PMID:35385113 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression ISO perchlorate results in decreased expression of CAMK4 mRNA CTD PMID:35385113 NCBI chr18:33,067,995...33,328,820
Ensembl chr18:33,067,984...33,324,281
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO perchlorate results in decreased activity of CA1 protein CTD PMID:15664814 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO perchlorate results in decreased activity of CA2 protein CTD PMID:15664814 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
G Car5a carbonic anhydrase 5a, mitochondrial decreases activity ISO perchlorate results in decreased activity of CA5A protein CTD PMID:15664814 NCBI chr 8:122,642,874...122,671,651
Ensembl chr 8:122,642,865...122,671,643
JBrowse link
G Car9 carbonic anhydrase 9 decreases activity ISO perchlorate results in decreased activity of CA9 protein CTD PMID:15664814 NCBI chr 4:43,507,026...43,513,729
Ensembl chr 4:43,506,966...43,513,729
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO perchlorate results in increased activity of CASP3 protein
Sodium Iodide promotes the reaction [perchlorate results in increased activity of CASP3 protein]
CTD PMID:11834455 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO [sodium perchlorate results in increased abundance of perchlorate] which results in increased expression of FOS protein CTD PMID:30991129 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Mir133a-1 microRNA 133a-1 multiple interactions EXP [Methimazole co-treated with perchlorate] results in increased expression of MIR133A1 mRNA CTD PMID:20808432 NCBI chr18:10,782,909...10,782,976
Ensembl chr18:10,782,909...10,782,976
JBrowse link
G Mir133b microRNA 133b multiple interactions EXP [Methimazole co-treated with perchlorate] results in increased expression of MIR133B mRNA CTD PMID:20808432 NCBI chr 1:20,752,993...20,753,111
Ensembl chr 1:20,752,993...20,753,111
JBrowse link
G Mir135a-2 microRNA 135a-2 multiple interactions EXP [Methimazole co-treated with perchlorate] results in increased expression of MIR135A mRNA CTD PMID:20808432 NCBI chr10:91,907,948...91,908,047
Ensembl chr10:91,907,948...91,908,047
JBrowse link
G Mir135b microRNA 135b multiple interactions EXP [Methimazole co-treated with perchlorate] results in increased expression of MIR135B mRNA CTD PMID:20808432 NCBI chr 1:132,125,826...132,125,922
Ensembl chr 1:132,125,826...132,125,922
JBrowse link
G Mir148a microRNA 148a multiple interactions EXP [Methimazole co-treated with perchlorate] results in decreased expression of MIR148A mRNA CTD PMID:20808432 NCBI chr 6:51,246,792...51,246,890
Ensembl chr 6:51,246,792...51,246,890
JBrowse link
G Mir199b microRNA 199b multiple interactions EXP [Methimazole co-treated with perchlorate] results in increased expression of MIR199B mRNA CTD PMID:20808432 NCBI chr 2:32,208,472...32,208,581
Ensembl chr 2:32,208,472...32,208,581
JBrowse link
G Mir206 microRNA 206 multiple interactions EXP [Methimazole co-treated with perchlorate] results in increased expression of MIR206 mRNA CTD PMID:20808432 NCBI chr 1:20,749,234...20,749,306
Ensembl chr 1:20,749,234...20,749,306
JBrowse link
G Papss1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 multiple interactions ISO perchlorate binds to and results in decreased activity of PAPSS1 protein CTD PMID:15065880 NCBI chr 3:131,270,626...131,349,432
Ensembl chr 3:131,270,529...131,349,432
JBrowse link
G Pax8 paired box 8 decreases expression ISO perchlorate results in decreased expression of PAX8 mRNA CTD PMID:35385113 NCBI chr 2:24,310,563...24,365,611
Ensembl chr 2:24,310,572...24,365,611
JBrowse link
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 affects expression ISO perchlorate affects the expression of SLC22A3 mRNA CTD PMID:21623536 NCBI chr17:12,638,859...12,726,591
Ensembl chr17:12,637,847...12,726,591
JBrowse link
G Slc26a4 solute carrier family 26, member 4 increases expression ISO perchlorate results in increased expression of SLC26A4 mRNA CTD PMID:35385113 NCBI chr12:31,569,813...31,610,054
Ensembl chr12:31,569,826...31,609,968
JBrowse link
G Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 increases expression
affects expression
multiple interactions
decreases activity
EXP
ISO
perchlorate results in increased expression of SLC5A5 protein
perchlorate results in increased expression of SLC5A5 mRNA
perchlorate affects the expression of SLC5A5 mRNA
perchlorate inhibits the reaction [mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]]; perchlorate inhibits the reaction [SLC5A5 protein results in increased abundance of Sodium Iodide]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]
perchlorate results in decreased activity of SLC5A5 protein
CTD PMID:12601449 PMID:14633711 PMID:15347726 PMID:15850642 PMID:15941870 More... NCBI chr 8:71,335,529...71,345,429
Ensembl chr 8:71,335,533...71,345,401
JBrowse link
G Tg thyroglobulin decreases expression EXP
ISO
perchlorate results in decreased expression of TG protein
perchlorate results in decreased expression of TG mRNA
CTD PMID:17332529 PMID:35385113 NCBI chr15:66,542,606...66,722,570
Ensembl chr15:66,542,602...66,722,570
JBrowse link
G Thrb thyroid hormone receptor beta decreases expression ISO perchlorate results in decreased expression of THRB mRNA CTD PMID:35385113 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435
JBrowse link
G Tpo thyroid peroxidase increases expression ISO perchlorate results in increased expression of TPO mRNA CTD PMID:35385113 NCBI chr12:30,104,658...30,182,983
Ensembl chr12:30,104,658...30,182,623
JBrowse link
G Tshb thyroid stimulating hormone, beta subunit increases expression
multiple interactions
EXP
ISO
perchlorate results in increased expression of TSHB protein
[Iodides deficiency co-treated with perchlorate] results in increased expression of TSHB protein
CTD PMID:17332529 PMID:20439182 NCBI chr 3:102,684,621...102,718,175
Ensembl chr 3:102,682,781...102,690,034
JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression ISO perchlorate results in decreased expression of TSHR mRNA CTD PMID:35385113 NCBI chr12:91,367,767...91,507,283
Ensembl chr12:91,351,337...91,516,582
JBrowse link
sodium chlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 decreases expression ISO sodium chlorate results in decreased expression of BMP4 mRNA CTD PMID:12922982 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
JBrowse link
G Cat catalase decreases activity ISO sodium chlorate results in decreased activity of CAT protein CTD PMID:28084674 PMID:30144278 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO sodium chlorate inhibits the reaction [CCL2 protein results in increased activity of CCR2 protein] CTD PMID:23408426 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
decreases sulfation
ISO sodium chlorate inhibits the reaction [CCL2 protein results in increased activity of CCR2 protein]
sodium chlorate results in decreased sulfation of CCR2 protein
CTD PMID:23408426 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Fbp1 fructose bisphosphatase 1 decreases activity ISO sodium chlorate results in decreased activity of FBP1 protein CTD PMID:28084674 NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096
JBrowse link
G Fgf10 fibroblast growth factor 10 affects activity EXP sodium chlorate affects the activity of FGF10 protein CTD PMID:12818887 NCBI chr13:118,851,199...118,928,651
Ensembl chr13:118,806,327...118,928,651
JBrowse link
G Fgf23 fibroblast growth factor 23 multiple interactions ISO sodium chlorate inhibits the reaction [FGF23 protein results in decreased uptake of Phosphates] CTD PMID:27432882 NCBI chr 6:127,049,865...127,059,257
Ensembl chr 6:127,049,865...127,058,371
JBrowse link
G Fshb follicle stimulating hormone beta multiple interactions ISO sodium chlorate inhibits the reaction [FSHB protein results in increased activity of PDE4A protein] CTD PMID:17261351 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases activity ISO sodium chlorate results in decreased activity of G6PD protein CTD PMID:28084674 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Gsr glutathione reductase decreases activity ISO sodium chlorate results in decreased activity of GSR protein CTD PMID:28084674 PMID:30144278 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Kl klotho decreases expression ISO sodium chlorate results in decreased expression of KL protein CTD PMID:27432882 NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 decreases phosphorylation
multiple interactions
EXP sodium chlorate results in decreased phosphorylation of MAPK1 protein
Heparin inhibits the reaction [sodium chlorate results in decreased phosphorylation of MAPK1 protein]
CTD PMID:19937756 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
EXP Heparin inhibits the reaction [sodium chlorate results in decreased phosphorylation of MAPK3 protein] CTD PMID:19937756 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Nanog Nanog homeobox increases expression EXP sodium chlorate results in increased expression of NANOG mRNA CTD PMID:19937756 NCBI chr 6:122,684,448...122,691,592
Ensembl chr 6:122,684,448...122,691,592
JBrowse link
G Pde4a phosphodiesterase 4A, cAMP specific multiple interactions ISO sodium chlorate inhibits the reaction [FSHB protein results in increased activity of PDE4A protein] CTD PMID:17261351 NCBI chr 9:21,076,998...21,124,544
Ensembl chr 9:21,073,005...21,124,544
JBrowse link
G Sftpc surfactant associated protein C decreases expression ISO sodium chlorate results in decreased expression of SFTPC mRNA CTD PMID:12922982 NCBI chr14:70,758,381...70,761,521
Ensembl chr14:70,758,389...70,761,521
JBrowse link
G Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 multiple interactions ISO sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] CTD PMID:12488351 NCBI chr 8:71,335,529...71,345,429
Ensembl chr 8:71,335,533...71,345,401
JBrowse link
sodium hypochlorite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, liver/bone/kidney increases expression ISO Sodium Hypochlorite results in increased expression of ALPL mRNA CTD PMID:22083529 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Sodium Hypochlorite results in increased expression of ATF3 mRNA CTD PMID:37149095 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Sodium Hypochlorite results in decreased expression of CCL2 mRNA CTD PMID:37149095 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Csrnp1 cysteine-serine-rich nuclear protein 1 increases expression ISO Sodium Hypochlorite results in increased expression of CSRNP1 mRNA CTD PMID:37149095 NCBI chr 9:119,800,229...119,813,808
Ensembl chr 9:119,800,229...119,813,724
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO Sodium Hypochlorite inhibits the reaction [bisphenol A binds to ESR2 protein]; Sodium Hypochlorite inhibits the reaction [Estradiol binds to ESR2 protein]; Sodium Hypochlorite inhibits the reaction [nonylphenol binds to ESR2 protein] CTD PMID:14723943 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Fosb FBJ osteosarcoma oncogene B increases expression ISO Sodium Hypochlorite results in increased expression of FOSB mRNA CTD PMID:37149095 NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976
JBrowse link
G Gm25279 predicted gene, 25279 decreases expression ISO Sodium Hypochlorite results in decreased expression of RNU4-39P CTD PMID:37149095 NCBI chr 1:151,730,622...151,730,706
Ensembl chr 1:151,730,574...151,730,706
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Sodium Hypochlorite results in increased expression of HMOX1 mRNA CTD PMID:37149095 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Sodium Hypochlorite results in decreased expression of HSD3B1 mRNA CTD PMID:37149095 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
JBrowse link
G Hspa1a heat shock protein 1A increases expression ISO Sodium Hypochlorite results in increased expression of HSPA1A mRNA CTD PMID:37149095 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Hspa1b heat shock protein 1B increases expression ISO Sodium Hypochlorite results in increased expression of HSPA1B mRNA CTD PMID:37149095 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
JBrowse link
G Ifna1 interferon alpha 1 increases expression ISO Sodium Hypochlorite results in increased expression of IFNA1 mRNA CTD PMID:37149095 NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893
JBrowse link
G Il24 interleukin 24 increases expression ISO Sodium Hypochlorite results in increased expression of IL24 mRNA CTD PMID:37149095 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
JBrowse link
G Junb jun B proto-oncogene increases expression ISO Sodium Hypochlorite results in increased expression of JUNB mRNA CTD PMID:37149095 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Sodium Hypochlorite promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Sodium Hypochlorite promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile] CTD PMID:25614581 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO Sodium Hypochlorite results in increased expression of NR4A1 mRNA CTD PMID:37149095 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Sodium Hypochlorite results in increased expression of NR4A2 mRNA CTD PMID:37149095 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO Sodium Hypochlorite results in increased expression of NR4A3 mRNA CTD PMID:37149095 NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Sodium Hypochlorite results in increased expression of PPP1R15A mRNA CTD PMID:37149095 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 increases expression ISO Sodium Hypochlorite results in increased expression of SLC7A11 mRNA CTD PMID:37149095 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 increases expression ISO Sodium Hypochlorite results in increased expression of SPRY2 mRNA CTD PMID:37149095 NCBI chr14:106,129,381...106,134,559
Ensembl chr14:106,129,381...106,134,253
JBrowse link
sodium perchlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 multiple interactions ISO [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of ALDH1L1 protein CTD PMID:30090431 NCBI chr 6:90,527,751...90,576,153
Ensembl chr 6:90,463,409...90,577,185
JBrowse link
G Aldh5a1 aldhehyde dehydrogenase family 5, subfamily A1 multiple interactions ISO [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of ALDH5A1 protein CTD PMID:30090431 NCBI chr13:25,091,562...25,121,740
Ensembl chr13:25,091,562...25,121,644
Ensembl chr13:25,091,562...25,121,644
JBrowse link
G Cga glycoprotein hormones, alpha subunit increases expression ISO sodium perchlorate results in increased expression of CGA mRNA; sodium perchlorate results in increased expression of CGA protein CTD PMID:29139221 NCBI chr 4:34,893,779...34,907,374
Ensembl chr 4:34,893,779...34,907,370
JBrowse link
G Cth cystathionine gamma lyase multiple interactions ISO [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of CTH protein CTD PMID:30090431 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
JBrowse link
G Cyb5a cytochrome b5 type A (microsomal) multiple interactions ISO [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in decreased expression of CYB5A protein CTD PMID:30090431 NCBI chr18:84,869,463...84,897,996
Ensembl chr18:84,856,829...84,897,996
JBrowse link
G Dio1 deiodinase, iodothyronine, type I decreases expression ISO sodium perchlorate results in decreased expression of DIO1 mRNA CTD PMID:29139221 NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO [sodium perchlorate results in increased abundance of perchlorate] which results in increased expression of FOS protein CTD PMID:30991129 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Ftcd formiminotransferase cyclodeaminase multiple interactions ISO [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in decreased expression of FTCD protein CTD PMID:30090431 NCBI chr10:76,411,482...76,426,172
Ensembl chr10:76,411,482...76,426,172
JBrowse link
G Gamt guanidinoacetate methyltransferase multiple interactions ISO [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of GAMT protein CTD PMID:30090431 NCBI chr10:80,093,985...80,096,846
Ensembl chr10:80,093,985...80,096,846
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO sodium perchlorate results in increased expression of and results in increased secretion of IFNG protein
sodium perchlorate results in increased expression of IFNG mRNA
CTD PMID:29139221 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO sodium perchlorate results in increased expression of IL1A mRNA CTD PMID:29139221 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO sodium perchlorate results in increased expression of and results in increased secretion of IL6 protein
sodium perchlorate results in increased expression of IL6 mRNA
CTD PMID:29139221 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Krt18 keratin 18 multiple interactions ISO [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of KRT18 protein CTD PMID:30090431 NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462
JBrowse link
G Lep leptin multiple interactions ISO [Iodine deficiency co-treated with sodium perchlorate] results in increased secretion of LEP protein CTD PMID:30090431 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lhb luteinizing hormone beta multiple interactions ISO [Iodine deficiency co-treated with sodium perchlorate] results in decreased secretion of LHB protein CTD PMID:30090431 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
JBrowse link
G Nkx2-1 NK2 homeobox 1 increases expression ISO sodium perchlorate results in increased expression of NKX2-1 protein CTD PMID:29139221 NCBI chr12:56,578,741...56,583,570
Ensembl chr12:56,578,743...56,583,693
JBrowse link
G Pax8 paired box 8 increases expression ISO sodium perchlorate results in increased expression of PAX8 protein CTD PMID:29139221 NCBI chr 2:24,310,563...24,365,611
Ensembl chr 2:24,310,572...24,365,611
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON1 protein; [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of PON1 protein CTD PMID:30090431 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Pon2 paraoxonase 2 multiple interactions ISO [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON2 protein CTD PMID:30090431 NCBI chr 6:5,264,620...5,298,408
Ensembl chr 6:5,264,147...5,298,455
JBrowse link
G Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 multiple interactions
increases expression
decreases activity
ISO sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Technetium]
sodium perchlorate results in increased expression of SLC5A5 mRNA; sodium perchlorate results in increased expression of SLC5A5 protein
sodium perchlorate results in decreased activity of SLC5A5 protein
CTD PMID:12488351 PMID:12489024 PMID:12541134 PMID:15221289 PMID:15520214 More... NCBI chr 8:71,335,529...71,345,429
Ensembl chr 8:71,335,533...71,345,401
JBrowse link
G Tg thyroglobulin increases expression ISO sodium perchlorate results in increased expression of TG protein CTD PMID:29139221 NCBI chr15:66,542,606...66,722,570
Ensembl chr15:66,542,602...66,722,570
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO sodium perchlorate results in increased expression of and results in increased secretion of TNF protein
sodium perchlorate results in increased expression of TNF mRNA
CTD PMID:29139221 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tpo thyroid peroxidase decreases activity
increases expression
ISO sodium perchlorate results in decreased activity of TPO protein
sodium perchlorate results in increased expression of TPO mRNA; sodium perchlorate results in increased expression of TPO protein
CTD PMID:23959146 PMID:29139221 NCBI chr12:30,104,658...30,182,983
Ensembl chr12:30,104,658...30,182,623
JBrowse link
G Trh thyrotropin releasing hormone increases expression
decreases expression
ISO sodium perchlorate results in increased expression of TRH mRNA
sodium perchlorate results in decreased expression of TRH protein
CTD PMID:29139221 NCBI chr 6:92,219,042...92,221,631
Ensembl chr 6:92,219,042...92,221,631
JBrowse link
G Tshb thyroid stimulating hormone, beta subunit multiple interactions
increases expression
ISO sodium perchlorate inhibits the reaction [efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]]; sodium perchlorate inhibits the reaction [Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]]
[Iodine deficiency co-treated with sodium perchlorate] results in increased secretion of TSHB protein
sodium perchlorate results in increased expression of TSHB mRNA; sodium perchlorate results in increased expression of TSHB protein
CTD PMID:16030158 PMID:29139221 PMID:30090431 NCBI chr 3:102,684,621...102,718,175
Ensembl chr 3:102,682,781...102,690,034
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO sodium perchlorate results in increased expression of TSHR mRNA; sodium perchlorate results in increased expression of TSHR protein CTD PMID:29139221 NCBI chr12:91,367,767...91,507,283
Ensembl chr12:91,351,337...91,516,582
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22252
    chemical entity 22251
      atom 22245
        nonmetal atom 22070
          halogen 20327
            halogen molecular entity 20327
              chlorine molecular entity 19751
                chlorine oxoanion 87
                  chlorate + 17
                  chlorite + 8
                  hypochlorite + 21
                  perchlorate + 46
Path 2
Term Annotations click to browse term
  CHEBI ontology 22252
    subatomic particle 22245
      composite particle 22245
        hadron 22245
          baryon 22245
            nucleon 22245
              atomic nucleus 22245
                atom 22245
                  main group element atom 22121
                    main group molecular entity 22121
                      p-block molecular entity 22121
                        chalcogen molecular entity 21453
                          oxygen molecular entity 21432
                            oxide 13377
                              oxoanion 10740
                                halogen oxoanion 251
                                  chlorine oxoanion 87
                                    chlorate + 17
                                    chlorite + 8
                                    hypochlorite + 21
                                    perchlorate + 46
paths to the root