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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 protein |
CTD |
PMID:12044520 |
|
NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
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|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 protein |
CTD |
PMID:12044520 |
|
NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
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G |
Actb |
actin, beta |
increases expression decreases expression |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased expression of ACTB mRNA Trinitrobenzenesulfonic Acid results in decreased expression of ACTB mRNA |
CTD |
PMID:12163651 PMID:17982090 |
|
NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
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G |
Adm2 |
adrenomedullin 2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of ADM2 mRNA |
CTD |
PMID:21808981 |
|
NCBI chr 7:130,296,895...130,298,641
Ensembl chr 7:130,296,897...130,298,644
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|
G |
Agr2 |
anterior gradient 2, protein disulphide isomerase family member |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of AGR2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:21131560 |
|
NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
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G |
Ak3 |
adenylate kinase 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of AK3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
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G |
Akap6 |
A-kinase anchoring protein 6 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of AKAP6 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
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|
G |
Akap9 |
A-kinase anchoring protein 9 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of AKAP9 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582
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|
G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of AKR1C2 mRNA |
CTD |
PMID:25724174 |
|
NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
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|
G |
Alb |
albumin |
increases secretion |
EXP |
Trinitrobenzenesulfonic Acid results in increased secretion of ALB protein |
CTD |
PMID:23307618 |
|
NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
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|
G |
Aldh1a3 |
aldehyde dehydrogenase 1 family, member A3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ALDH1A3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
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G |
Alpi |
alkaline phosphatase, intestinal |
increases activity multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein] |
CTD |
PMID:15867298 |
|
NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
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|
G |
Anxa1 |
annexin A1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ANXA1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
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G |
Anxa8 |
annexin A8 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ANXA8 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr16:10,417,174...10,432,388
Ensembl chr16:10,417,185...10,432,393
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|
G |
Apbb1ip |
amyloid beta precursor protein binding family B member 1 interacting protein |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of APBB1IP mRNA |
CTD |
PMID:17982090 |
|
NCBI chr17:90,098,953...90,149,192
Ensembl chr17:90,099,025...90,149,894
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|
G |
Apob |
apolipoprotein B |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of APOB mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
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G |
Aqp3 |
aquaporin 3 (Gill blood group) |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of AQP3 mRNA |
CTD |
PMID:15140218 |
|
NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
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G |
Aqp4 |
aquaporin 4 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of AQP4 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
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G |
Arfip1 |
ADP-ribosylation factor interacting protein 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of ARFIP1 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:183,503,250...183,582,798
Ensembl chr 2:183,504,330...183,582,553
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G |
Arg1 |
arginase 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ARG1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
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G |
Arg2 |
arginase 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ARG2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
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|
G |
Arhgap24 |
Rho GTPase activating protein 24 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ARHGAP24 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512
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|
G |
Arhgdib |
Rho GDP dissociation inhibitor beta |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARHGDIB mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
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|
G |
Arl4d |
ADP-ribosylation factor like GTPase 4D |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of ARL4D mRNA |
CTD |
PMID:23537331 |
|
NCBI chr10:89,577,556...89,580,368
Ensembl chr10:89,578,212...89,580,368
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G |
Arrb1 |
arrestin, beta 1 |
multiple interactions increases expression |
EXP |
Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein] Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein |
CTD |
PMID:24637189 |
|
NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
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G |
Atoh1 |
atonal bHLH transcription factor 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of ATOH1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 4:95,498,003...95,500,098
Ensembl chr 4:95,498,003...95,500,089
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|
G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 protein |
CTD |
PMID:17131044 |
|
NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
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G |
Atp4a |
ATPase H+/K+ transporting subunit alpha |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ATP4A mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:89,162,700...89,175,504
Ensembl chr 1:89,162,639...89,175,811
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions increases expression |
EXP |
Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAK1 mRNA] |
CTD |
PMID:15502641 |
|
NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
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G |
Basp1 |
brain abundant, membrane attached signal protein 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of BASP1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
EXP ISO |
Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA] Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BAX protein D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BAX protein] |
CTD |
PMID:15502641 PMID:22427801 PMID:24831514 PMID:31428839 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions increases expression decreases expression |
EXP |
Losartan promotes the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein |
CTD |
PMID:15502641 PMID:24637189 PMID:24831514 PMID:31428839 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Bcl2a1 |
BCL2-related protein A1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of BCL2A1B mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
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|
G |
Bcl2l11 |
BCL2 like 11 |
multiple interactions increases expression |
ISO |
[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BCL2L11 protein] Trinitrobenzenesulfonic Acid results in increased expression of BCL2L11 protein |
CTD |
PMID:22427801 |
|
NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
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G |
Bcl3 |
BCL3, transcription coactivator |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL3 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
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G |
Becn1 |
beclin 1 |
multiple interactions increases expression |
EXP |
Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein] |
CTD |
PMID:30503585 |
|
NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
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|
G |
Bglap |
bone gamma-carboxyglutamate protein |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of BGLAP protein |
CTD |
PMID:23747339 |
|
NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
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G |
Bgn |
biglycan |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr X:157,319,042...157,331,204
Ensembl chr X:157,319,046...157,331,204
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|
G |
Bpnt2 |
3'(2'), 5'-bisphosphate nucleotidase 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of BPNT2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr17:90,191,119...90,218,013
Ensembl chr17:90,188,043...90,218,013 Ensembl chr 5:90,188,043...90,218,013
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G |
C1qb |
complement C1q B chain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C1QB mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
|
|
G |
C1qc |
complement C1q C chain |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of C1QC mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 5:155,255,013...155,258,631
Ensembl chr 5:155,255,005...155,258,392
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|
G |
C3 |
complement C3 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
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|
G |
C4b |
complement C4B (Chido blood group) |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
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|
G |
Ca3 |
carbonic anhydrase 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CAR3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
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|
G |
Cab39 |
calcium binding protein 39 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of CAB39 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778
|
|
G |
Cacna1c |
calcium voltage-gated channel subunit alpha1 C |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C protein |
CTD |
PMID:23537331 |
|
NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
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|
G |
Cacna1e |
calcium voltage-gated channel subunit alpha1 E |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E protein |
CTD |
PMID:23537331 |
|
NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980
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|
G |
Calcb |
calcitonin-related polypeptide, beta |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of CALCB mRNA |
CTD |
PMID:21808981 |
|
NCBI chr 1:184,271,116...184,276,480
Ensembl chr 1:184,271,590...184,276,475
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|
G |
Calcrl |
calcitonin receptor like receptor |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of CALCRL mRNA |
CTD |
PMID:21808981 |
|
NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
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G |
Camk2b |
calcium/calmodulin-dependent protein kinase II beta |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of CAMK2B mRNA |
CTD |
PMID:23537331 |
|
NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
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G |
Capg |
capping actin protein, gelsolin like |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPG mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
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|
G |
Capn1 |
calpain 1 |
multiple interactions increases expression |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein] |
CTD |
PMID:30503585 |
|
NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
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|
G |
Casp1 |
caspase 1 |
multiple interactions increases expression |
EXP |
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein |
CTD |
PMID:30365937 PMID:30503585 |
|
NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
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|
G |
Casp12 |
caspase 12 |
multiple interactions increases cleavage |
EXP |
Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP12 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] |
CTD |
PMID:30503585 |
|
NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
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|
G |
Casp3 |
caspase 3 |
multiple interactions increases expression |
ISO EXP |
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of CASP3 protein]; Trinitrobenzenesulfonic Acid results in increased cleavage of and results in increased activity of CASP3 protein Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein |
CTD |
PMID:22427801 PMID:24831514 PMID:26165751 PMID:30503585 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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|
G |
Casp4 |
caspase 4 |
multiple interactions |
EXP |
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein |
CTD |
PMID:30365937 |
|
NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
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|
G |
Casp8 |
caspase 8 |
multiple interactions decreases expression |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form] |
CTD |
PMID:30503585 |
|
NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
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|
G |
Casp9 |
caspase 9 |
increases expression multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form] |
CTD |
PMID:30503585 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
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G |
Cat |
catalase |
increases expression multiple interactions decreases expression |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased expression of CAT mRNA Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA] |
CTD |
PMID:17982090 PMID:30503585 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression increases secretion multiple interactions |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein Trinitrobenzenesulfonic Acid results in increased secretion of CCL2 protein icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein] Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA] |
CTD |
PMID:17449585 PMID:17982090 PMID:23307618 PMID:23596210 PMID:30503585 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO |
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein] |
CTD |
PMID:21599020 PMID:23596210 |
|
NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
multiple interactions increases expression |
ISO |
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL4 protein] |
CTD |
PMID:23596210 |
|
NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CCL7 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
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G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions increases expression |
ISO |
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA] |
CTD |
PMID:25740948 |
|
NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
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|
G |
Ccn4 |
cellular communication network factor 4 |
multiple interactions decreases expression increases expression |
ISO EXP |
NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA] Trinitrobenzenesulfonic Acid results in decreased expression of CCN4 mRNA |
CTD |
PMID:19238344 PMID:23537331 |
|
NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772
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G |
Ccnb1 |
cyclin B1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CCNB1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CCR2 mRNA |
CTD |
PMID:17982090 |
|
|
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G |
Ccr5 |
C-C motif chemokine receptor 5 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CCR5 mRNA |
CTD |
PMID:15973123 PMID:17982090 |
|
NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
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G |
Cd14 |
CD14 molecule |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CD14 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
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G |
Cd3g |
CD3g molecule |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of CD3G mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
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G |
Cd44 |
CD44 molecule (Indian blood group) |
multiple interactions increases expression |
ISO |
seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD44 protein] |
CTD |
PMID:11717450 |
|
NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
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G |
Cd47 |
Cd47 molecule |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD47 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
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G |
Cd53 |
Cd53 molecule |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CD53 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:209,489,279...209,537,098
Ensembl chr 2:209,489,279...209,537,087
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|
G |
Cd79a |
CD79a molecule |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CD79A mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:81,763,609...81,768,039
Ensembl chr 1:81,763,614...81,767,980
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G |
Cdh17 |
cadherin 17 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of CDH17 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 5:25,354,187...25,443,675
Ensembl chr 5:25,391,115...25,443,718
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|
G |
Cdr2 |
cerebellar degeneration-related protein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CDR2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:190,889,698...190,914,606
Ensembl chr 1:190,889,701...190,914,610
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|
G |
Ceacam4 |
CEA cell adhesion molecule 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CEACAM10 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:81,643,809...81,650,085
Ensembl chr 1:81,643,816...81,650,094
|
|
G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CEBPB mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
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|
G |
Cel |
carboxyl ester lipase |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CEL mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
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G |
Cela2a |
chymotrypsin like elastase 2A |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CELA2A mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 5:160,374,031...160,383,782
Ensembl chr 5:160,374,031...160,383,782
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G |
Ces1d |
carboxylesterase 1D |
increases expression decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CES1 mRNA Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA] |
CTD |
PMID:18200517 PMID:19524605 PMID:22609641 |
|
NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
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G |
Ces3a |
carboxylesterase 3a |
decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr19:37,070,705...37,079,411
|
|
G |
Cfd |
complement factor D |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CFD mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
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G |
Cfh |
complement factor H |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CFH mRNA |
CTD |
PMID:17982090 |
|
NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
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|
G |
Chi3l1 |
chitinase 3 like 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CHI3L1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
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|
G |
Chkb |
choline kinase beta |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CHKB mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 7:130,404,818...130,408,813
Ensembl chr 7:130,404,832...130,408,187
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G |
Clca1 |
chloride channel accessory 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CLCA1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744
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G |
Cldn1 |
claudin 1 |
multiple interactions decreases expression |
ISO |
ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein] |
CTD |
PMID:22849695 |
|
NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions increases expression |
ISO |
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A1 mRNA] |
CTD |
PMID:17982090 PMID:25740948 |
|
NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions increases expression |
ISO |
6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA] |
CTD |
PMID:17982090 PMID:18200517 PMID:20889569 |
|
NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
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G |
Col4a1 |
collagen type IV alpha 1 chain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
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|
G |
Col4a2 |
collagen type IV alpha 2 chain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr16:83,386,388...83,522,169
Ensembl chr16:83,387,364...83,438,561
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|
G |
Col5a1 |
collagen type V alpha 1 chain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
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G |
Col5a2 |
collagen type V alpha 2 chain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
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G |
Cort |
cortistatin |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of CORT protein |
CTD |
PMID:11959675 |
|
NCBI chr 5:165,942,780...165,944,221
|
|
G |
Crh |
corticotropin releasing hormone |
decreases expression increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of CRH mRNA Trinitrobenzenesulfonic Acid results in increased expression of CRH mRNA |
CTD |
PMID:11668029 PMID:11959675 |
|
NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
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|
G |
Crhr1 |
corticotropin releasing hormone receptor 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of CRHR1 mRNA |
CTD |
PMID:15178552 |
|
NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
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|
G |
Csf2rb |
colony stimulating factor 2 receptor subunit beta |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 7:119,554,383...119,568,248
Ensembl chr 7:119,554,354...119,568,776
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G |
Csf3 |
colony stimulating factor 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CSF3 protein |
CTD |
PMID:23596210 |
|
NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions increases expression |
EXP |
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein] Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein |
CTD |
PMID:26165751 |
|
NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
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G |
Ctsc |
cathepsin C |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CTSC mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CX3CL1 mRNA |
CTD |
PMID:15973123 |
|
NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL10 protein |
CTD |
PMID:23596210 |
|
NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL12 mRNA |
CTD |
PMID:15973123 |
|
NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
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G |
Cxcl13 |
C-X-C motif chemokine ligand 13 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL13 mRNA |
CTD |
PMID:15973123 |
|
NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207
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G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL14 mRNA |
CTD |
PMID:15973123 |
|
NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL2 mRNA] |
CTD |
PMID:17375199 PMID:18200517 |
|
NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO |
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein] Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein |
CTD |
PMID:17982090 PMID:23596210 |
|
NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL5 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL9 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
|
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G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCR2 mRNA |
CTD |
PMID:15973123 |
|
NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
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G |
Cycs |
cytochrome c, somatic |
multiple interactions increases expression |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA] Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein |
CTD |
PMID:24831514 PMID:30503585 |
|
NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
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|
G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP1A2 protein |
CTD |
PMID:18079364 |
|
NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
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|
G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
multiple interactions |
EXP |
gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein |
CTD |
PMID:18079364 |
|
NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
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|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2E1 protein |
CTD |
PMID:18079364 |
|
NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions |
EXP |
gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein |
CTD |
PMID:18079364 |
|
NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
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|
G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CYP3A13 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
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|
G |
Dcp2 |
decapping mRNA 2 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of DCP2 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr18:35,489,274...35,671,676
Ensembl chr18:35,489,274...35,672,291
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|
G |
Defb2 |
defensin beta 2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of DEFB2 mRNA |
CTD |
PMID:19998380 |
|
NCBI chr16:75,227,468...75,241,303
Ensembl chr16:75,227,468...75,241,303
|
|
G |
Dnaaf5 |
dynein, axonemal, assembly factor 5 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of DNAAF5 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr12:17,545,468...17,584,466
Ensembl chr12:17,545,468...17,584,466
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G |
Dpp4 |
dipeptidylpeptidase 4 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of DPP4 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
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|
G |
Dsg2 |
desmoglein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of DSG2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr18:15,579,322...15,637,720
Ensembl chr18:15,579,315...15,637,715
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|
G |
Eef1a1 |
eukaryotic translation elongation factor 1 alpha 1 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of EEF1A1 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
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|
G |
Eif4a2 |
eukaryotic translation initiation factor 4A2 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of EIF4A2 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
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|
G |
Eif4ebp2 |
eukaryotic translation initiation factor 4E binding protein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of EIF4EBP2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr20:31,055,292...31,072,469
Ensembl chr20:31,055,789...31,072,469
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|
G |
Emb |
embigin |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of EMB mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 2:49,682,763...49,733,475
Ensembl chr 2:49,682,754...49,732,253
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|
G |
Ephb3 |
Eph receptor B3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of EPHB3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr11:83,527,960...83,546,742
Ensembl chr11:83,527,962...83,546,674
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|
G |
Fabp2 |
fatty acid binding protein 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of FABP2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
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|
G |
Faslg |
Fas ligand |
multiple interactions increases expression |
ISO |
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of FASL protein] Trinitrobenzenesulfonic Acid results in increased expression of FASL protein |
CTD |
PMID:22427801 |
|
NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
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|
G |
Fbln2 |
fibulin 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 4:122,835,237...122,895,127
Ensembl chr 4:122,835,436...122,895,121
|
|
G |
Fbxl2 |
F-box and leucine-rich repeat protein 2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of FBXL2 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 8:122,240,393...122,290,439
Ensembl chr 8:122,243,016...122,311,431
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|
G |
Fcgr2b |
Fc fragment of IgG receptor IIb |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of FCGR2B mRNA |
CTD |
PMID:19524605 |
|
NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
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|
G |
Fcgr3a |
Fc fragment of IgG receptor IIIa |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FCGR3A mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051
|
|
G |
Fgf17 |
fibroblast growth factor 17 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of FGF17 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr15:52,326,758...52,337,360
Ensembl chr15:52,326,778...52,332,097
|
|
G |
Fgfr3 |
fibroblast growth factor receptor 3 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of FGFR3 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
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|
G |
Fn1 |
fibronectin 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FN1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of FOS mRNA |
CTD |
PMID:15178552 |
|
NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
|
|
G |
Fpr3 |
formyl peptide receptor 3 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FPR3 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 1:116,152,526...116,161,873
Ensembl chr 1:116,152,667...116,153,722
|
|
G |
Fstl1 |
follistatin-like 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FSTL1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr11:65,791,196...65,845,721
Ensembl chr11:65,782,567...65,845,418
|
|
G |
Fxyd5 |
FXYD domain-containing ion transport regulator 5 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of FXYD5 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 1:89,464,853...89,474,450
Ensembl chr 1:89,464,860...89,474,252
|
|
G |
Gabbr1 |
gamma-aminobutyric acid type B receptor subunit 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GABBR1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
|
|
G |
Gbp2 |
guanylate binding protein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GBP2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
|
|
G |
Gch1 |
GTP cyclohydrolase 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GCH1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
EXP |
[Trinitrobenzenesulfonic Acid co-treated with Ethanol] results in increased expression of GCLC mRNA |
CTD |
PMID:10830784 |
|
NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GCLM mRNA |
CTD |
PMID:22609641 |
|
NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
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|
G |
Gda |
guanine deaminase |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GDA mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732
|
|
G |
Gdpd3 |
glycerophosphodiester phosphodiesterase domain containing 3 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of GDPD3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150
|
|
G |
Ggta1 |
glycoprotein alpha-galactosyltransferase 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 3:14,614,099...14,701,185
Ensembl chr 3:14,614,122...14,644,951
|
|
G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
multiple interactions decreases expression |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA] |
CTD |
PMID:30503585 |
|
NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
|
|
G |
Got1l1 |
glutamic-oxaloacetic transaminase 1-like 1 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1L1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr16:69,022,756...69,035,507
Ensembl chr16:69,022,784...69,028,179
|
|
G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
decreases expression multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA] |
CTD |
PMID:30503585 |
|
NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
|
|
G |
Gpx2 |
glutathione peroxidase 2 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of GPX2 mRNA |
CTD |
PMID:31669340 |
|
NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
|
|
G |
Grb10 |
growth factor receptor bound protein 10 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GRB10 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr14:92,021,851...92,122,249
Ensembl chr14:92,021,851...92,117,923
|
|
G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
|
|
G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of GRIA2 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
|
|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases expression multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] |
CTD |
PMID:26165751 |
|
NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
|
|
G |
Gsn |
gelsolin |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
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|
G |
Gsr |
glutathione-disulfide reductase |
decreases activity decreases expression multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein Trinitrobenzenesulfonic Acid results in decreased expression of GSR mRNA 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein]; 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSR mRNA] |
CTD |
PMID:31669340 |
|
NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
|
|
G |
Gstm2 |
glutathione S-transferase mu 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of GSTM2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
|
|
G |
Gstt1 |
glutathione S-transferase theta 1 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of GSTT1 mRNA |
CTD |
PMID:31669340 |
|
NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression increases secretion |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of HAVCR1 mRNA Trinitrobenzenesulfonic Acid results in increased secretion of HAVCR1 protein |
CTD |
PMID:23307618 |
|
NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
|
|
G |
Hebp2 |
heme binding protein 2 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 1:13,713,152...13,719,970
Ensembl chr 1:13,714,440...13,719,829
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HMGCR mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
EXP |
Heme promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein; zinc protoporphyrin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of HMOX1 protein] Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein |
CTD |
PMID:17292349 PMID:25469038 PMID:30503585 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Hoxd13 |
homeo box D13 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HOXD13 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 3:61,590,376...61,593,692
Ensembl chr 3:61,590,376...61,593,692
|
|
G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
affects expression |
EXP |
Trinitrobenzenesulfonic Acid affects the expression of HPGD mRNA |
CTD |
PMID:25526689 |
|
NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
|
|
G |
Hrh4 |
histamine receptor H4 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of HRH4 mRNA |
CTD |
PMID:24561612 |
|
NCBI chr18:4,365,429...4,382,599
Ensembl chr18:4,365,429...4,382,599
|
|
G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of HSD11B1 mRNA |
CTD |
PMID:21513799 |
|
NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
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|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein] |
CTD |
PMID:30503585 |
|
NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
|
|
G |
Hspb7 |
heat shock protein family B (small) member 7 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPB7 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 5:159,968,077...159,971,563
Ensembl chr 5:159,967,839...159,971,562
|
|
G |
Htr1a |
5-hydroxytryptamine receptor 1A |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of HTR1A mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
|
|
G |
Htr2a |
5-hydroxytryptamine receptor 2A |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of HTR2A mRNA |
CTD |
PMID:23537331 |
|
NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions increases expression |
ISO EXP |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA] |
CTD |
PMID:18200517 PMID:22029500 PMID:26165751 PMID:30503585 PMID:31428839 |
|
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
|
|
G |
Ido1 |
indoleamine 2,3-dioxygenase 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IDO1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
|
|
G |
Ifi27 |
interferon, alpha-inducible protein 27 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of IFI27 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:127,327,959...127,334,430
Ensembl chr 6:127,327,959...127,334,428
|
|
G |
Ifi30 |
IFI30, lysosomal thiol reductase |
multiple interactions |
EXP |
[topiramate co-treated with Trinitrobenzenesulfonic Acid] results in decreased expression of IFI30 mRNA |
CTD |
PMID:21849664 |
|
NCBI chr16:20,426,566...20,430,772
Ensembl chr16:20,426,566...20,430,752
|
|
G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IFIT2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
|
|
G |
Ifitm3 |
interferon induced transmembrane protein 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IFITM3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:213,810,712...213,811,821
Ensembl chr 1:213,810,696...213,811,901
|
|
G |
Ifnb1 |
interferon beta 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IFNB1 mRNA |
CTD |
PMID:17375199 |
|
NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
|
|
G |
Ifng |
interferon gamma |
multiple interactions increases expression decreases expression |
EXP ISO |
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein] Trinitrobenzenesulfonic Acid results in decreased expression of IFNG mRNA Trinitrobenzenesulfonic Acid results in increased expression of IFNG; Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein] |
CTD |
PMID:11717450 PMID:15973123 PMID:16782535 PMID:16867261 PMID:19285099 PMID:20136961 PMID:21122500 PMID:21599020 PMID:21829567 PMID:22147983 PMID:23027085 PMID:23537331 PMID:23747339 PMID:24066068 PMID:27783946 PMID:30365937 |
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NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions increases expression |
ISO EXP |
6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein] Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein |
CTD |
PMID:18200517 PMID:20889569 PMID:24782617 |
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NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP4 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
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G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP5 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
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G |
Il10 |
interleukin 10 |
multiple interactions decreases secretion increases expression decreases expression |
EXP ISO |
[iberogast analog co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; [iberogast co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein] Trinitrobenzenesulfonic Acid results in decreased secretion of IL10 protein Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA Trinitrobenzenesulfonic Acid results in decreased expression of IL10; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein [cholan-2,3,24-tryl-2,3,24-trisulfate co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein] |
CTD |
PMID:11717450 PMID:15604057 PMID:15973123 PMID:16867261 PMID:17375199 PMID:19196500 PMID:21599020 PMID:21829567 PMID:22060784 PMID:24316276 PMID:24831514 PMID:25307695 PMID:25727887 PMID:25729217 PMID:30365937 |
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NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
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G |
Il12a |
interleukin 12A |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL12A mRNA |
CTD |
PMID:15973123 |
|
NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
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G |
Il12b |
interleukin 12B |
decreases response to substance increases expression multiple interactions |
ISO EXP |
IL12B protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein] Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA] |
CTD |
PMID:11782017 PMID:16867261 PMID:17375199 PMID:23596210 |
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NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
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G |
Il15 |
interleukin 15 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL15 protein |
CTD |
PMID:23596210 |
|
NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
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G |
Il17a |
interleukin 17A |
increases expression multiple interactions |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased expression of IL17A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein] [Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein |
CTD |
PMID:17375199 PMID:23027085 PMID:27783946 PMID:31428839 |
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NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
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G |
Il18 |
interleukin 18 |
increases expression multiple interactions |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased expression of IL18 mRNA bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein] |
CTD |
PMID:15973123 PMID:30365937 |
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NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
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G |
Il1a |
interleukin 1 alpha |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL1A mRNA icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein] |
CTD |
PMID:12781210 PMID:23596210 |
|
NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
ISO EXP |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] |
CTD |
PMID:15140218 PMID:15604057 PMID:15793857 PMID:15867298 PMID:15973123 PMID:16782535 PMID:16867261 PMID:17375077 PMID:17375199 PMID:17449585 PMID:17982090 PMID:18200517 PMID:19597321 PMID:19956958 PMID:20868668 PMID:20923188 PMID:21513799 PMID:21829567 PMID:21893697 PMID:22039321 PMID:22060784 PMID:22119283 PMID:22609641 PMID:23596210 PMID:23747339 PMID:25079872 PMID:25307695 PMID:25576893 PMID:25727887 PMID:25729217 PMID:26165751 PMID:30365937 PMID:30503585 |
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NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Il1r1 |
interleukin 1 receptor type 1 |
multiple interactions increases expression |
EXP |
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA] |
CTD |
PMID:17449585 |
|
NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
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G |
Il1rl1 |
interleukin 1 receptor-like 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL1RL1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
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G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions increases expression |
EXP |
Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA] |
CTD |
PMID:15867298 PMID:17375077 |
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NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
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G |
Il2 |
interleukin 2 |
multiple interactions increases expression |
ISO |
seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL2 mRNA] |
CTD |
PMID:11717450 PMID:27783946 |
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NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
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G |
Il23a |
interleukin 23 subunit alpha |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL23A mRNA |
CTD |
PMID:17375199 |
|
NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
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G |
Il4 |
interleukin 4 |
increases expression decreases secretion decreases expression multiple interactions |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased expression of IL4 mRNA Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein] |
CTD |
PMID:15973123 PMID:16782535 PMID:16867261 PMID:25729217 PMID:27783946 |
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NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
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G |
Il6 |
interleukin 6 |
multiple interactions decreases expression increases expression |
ISO EXP |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein] Trinitrobenzenesulfonic Acid results in decreased expression of IL6 mRNA Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of IL6; Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein |
CTD |
PMID:17375199 PMID:18079364 PMID:18200517 PMID:19956958 PMID:19998380 PMID:20923188 PMID:21070844 PMID:21829567 PMID:22060784 PMID:22410118 PMID:23027085 PMID:23596210 PMID:23747339 PMID:25307695 PMID:25472953 PMID:25576893 PMID:30503585 PMID:31428839 |
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NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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G |
Insl3 |
insulin-like 3 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of INSL3 mRNA |
CTD |
PMID:23537331 |
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NCBI chr16:20,120,753...20,122,702
Ensembl chr16:20,121,352...20,122,696
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G |
Irf1 |
interferon regulatory factor 1 |
decreases response to substance |
ISO |
IRF1 protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:21097874 |
|
NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
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G |
Isg15 |
ISG15 ubiquitin-like modifier |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ISG15 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
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G |
Itm2a |
integral membrane protein 2A |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ITM2A mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr X:78,490,872...78,496,814
Ensembl chr X:78,490,866...78,496,847
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G |
Itpr2 |
inositol 1,4,5-trisphosphate receptor, type 2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of ITPR2 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 4:180,423,452...180,800,088
Ensembl chr 4:180,538,389...180,722,358
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein |
CTD |
PMID:22427801 |
|
NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
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G |
Kcnab1 |
potassium voltage-gated channel subfamily A member regulatory beta subunit 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of KCNAB1 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:155,555,798...156,011,438
Ensembl chr 2:155,718,359...156,009,526
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G |
Kcnj4 |
potassium inwardly-rectifying channel, subfamily J, member 4 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of KCNJ4 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 7:120,717,378...120,744,602
Ensembl chr 7:120,717,375...120,744,602
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G |
Kcnq4 |
potassium voltage-gated channel subfamily Q member 4 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of KCNQ4 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 5:139,625,783...139,677,300
Ensembl chr 5:139,627,576...139,677,300
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G |
Kctd9 |
potassium channel tetramerization domain containing 9 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of KCTD9 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr15:44,411,591...44,439,645
Ensembl chr15:44,411,865...44,439,236
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G |
Kitlg |
KIT ligand |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of KITLG mRNA |
CTD |
PMID:17385238 |
|
NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
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G |
Kl |
Klotho |
multiple interactions decreases expression |
ISO |
KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein] Trinitrobenzenesulfonic Acid results in decreased expression of KL protein |
CTD |
PMID:23747339 |
|
NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
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G |
L1cam |
L1 cell adhesion molecule |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of L1CAM mRNA |
CTD |
PMID:17982090 |
|
NCBI chr X:156,901,244...156,928,064
Ensembl chr X:156,909,913...156,928,057
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G |
Lama3 |
laminin subunit alpha 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LAMA3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr18:3,704,866...3,941,215
Ensembl chr18:3,705,916...3,940,838
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G |
Lbp |
lipopolysaccharide binding protein |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LBP mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
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G |
Lcn2 |
lipocalin 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCN2 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
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G |
Lcp1 |
lymphocyte cytosolic protein 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr15:57,170,566...57,277,811
Ensembl chr15:57,221,292...57,277,811
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G |
Lgmn |
legumain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LGMN mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 6:126,282,246...126,308,207
Ensembl chr 6:126,282,233...126,320,726
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G |
Lilrb4 |
leukocyte immunoglobulin like receptor B4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LILRB4 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
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G |
LOC100365958 |
Rdh2 protein-like |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RDH16 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 7:71,065,077...71,074,128
Ensembl chr 7:70,980,422...71,072,689
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G |
Lox |
lysyl oxidase |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
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G |
Lrg1 |
leucine-rich alpha-2-glycoprotein 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LRG1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
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G |
Lst1 |
leukocyte specific transcript 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LST1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr20:5,175,213...5,179,352
Ensembl chr20:5,176,016...5,179,263
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G |
Lum |
lumican |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LUM mRNA |
CTD |
PMID:17982090 |
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NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
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G |
Ly86 |
lymphocyte antigen 86 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LY86 mRNA |
CTD |
PMID:17982090 |
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NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436
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G |
Lyz2 |
lysozyme 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LYZ mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 7:60,335,968...60,341,264
Ensembl chr 7:60,335,969...60,341,264
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G |
Madcam1 |
mucosal vascular addressin cell adhesion molecule 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MADCAM1 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 7:12,918,352...12,922,509
Ensembl chr 7:12,918,710...12,922,112
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G |
Maf |
MAF bZIP transcription factor |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MAF protein sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF protein] |
CTD |
PMID:24066068 |
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NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748
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G |
Manf |
mesencephalic astrocyte-derived neurotrophic factor |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MANF mRNA |
CTD |
PMID:17982090 |
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NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...115,626,380
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G |
Maoa |
monoamine oxidase A |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNA] |
CTD |
PMID:18200517 |
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NCBI chr X:6,554,698...6,620,722
Ensembl chr X:6,554,698...6,620,722
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases lipidation |
EXP |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:30503585 |
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NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
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G |
Map3k6 |
mitogen-activated protein kinase kinase kinase 6 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of MAP3K6 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 5:151,435,679...151,448,329
Ensembl chr 5:151,436,464...151,448,328
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G |
Mapk6 |
mitogen-activated protein kinase 6 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of MAPK6 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 8:82,328,013...82,351,108
Ensembl chr 8:82,328,020...82,351,108
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of MAPK8 mRNA |
CTD |
PMID:23537331 |
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NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases expression |
ISO |
[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] |
CTD |
PMID:22427801 |
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NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
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G |
Marcksl1 |
MARCKS-like 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MARCKSL1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 5:147,714,163...147,716,486
Ensembl chr 5:147,714,163...147,716,485
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G |
Me1 |
malic enzyme 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ME1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
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G |
Mettl7a |
methyltransferase like 7A |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of METTL7A mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 7:141,973,447...142,021,344
Ensembl chr 7:141,973,553...141,981,432
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G |
Mgp |
matrix Gla protein |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MGP mRNA |
CTD |
PMID:17982090 |
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NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
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G |
Mir155 |
microRNA 155 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MIR155 mRNA sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MIR155 mRNA] |
CTD |
PMID:24066068 |
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NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
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G |
Mir29a |
microRNA 29a |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MIR29A mRNA |
CTD |
PMID:25277410 |
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NCBI chr 4:58,343,931...58,344,018
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G |
Mir29b1 |
microRNA 29b-1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MIR29B-1 mRNA |
CTD |
PMID:25277410 |
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NCBI chr 4:58,344,310...58,344,390
Ensembl chr 4:58,344,310...58,344,390
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G |
Mki67 |
marker of proliferation Ki-67 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MKI67 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions increases expression |
EXP |
ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein]; ilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein |
CTD |
PMID:18837084 |
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NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
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G |
Mmp12 |
matrix metallopeptidase 12 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MMP12 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
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G |
Mmp14 |
matrix metallopeptidase 14 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP14 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
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G |
Mmp15 |
matrix metallopeptidase 15 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MMP15 mRNA |
CTD |
PMID:17982090 |
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NCBI chr19:10,079,881...10,101,380
Ensembl chr19:10,079,765...10,101,451
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP2 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
EXP |
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein |
CTD |
PMID:22119283 |
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NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
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G |
Mnda |
myeloid cell nuclear differentiation antigen |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IFI204 mRNA Trinitrobenzenesulfonic Acid results in increased expression of MNDA mRNA |
CTD |
PMID:17982090 |
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NCBI chr13:92,073,664...92,091,335
Ensembl chr13:92,073,668...92,089,980
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G |
Moxd2 |
monooxygenase, DBH-like 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of MOXD2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
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G |
Mpo |
myeloperoxidase |
multiple interactions increases activity increases expression |
EXP ISO |
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [potassium oxonate co-treated with Inosine Monophosphate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Cadmium Chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ciprofloxacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Heme inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Indomethacin inhibits the reaction [Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Indomethacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; N-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifampin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Spironolactone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; tin protoporphyrin IX promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zileuton inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zinc protoporphyrin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; J 113397 inhibits the reaction [8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; morphiceptin analog affects the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D2 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; RN 1734 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ruthenium Red inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] Trinitrobenzenesulfonic Acid results in increased expression of MPO; Trinitrobenzenesulfonic Acid results in increased expression of MPO protein |
CTD |
PMID:10845656 PMID:10877837 PMID:11137876 PMID:11504810 PMID:11668029 PMID:11698051 PMID:11959675 PMID:16474422 PMID:16804969 PMID:16867261 PMID:17276891 PMID:17292349 PMID:17375077 PMID:17375199 PMID:17553498 PMID:17936198 PMID:17991707 PMID:18288370 PMID:19002562 PMID:19234664 PMID:19597321 PMID:19956958 PMID:20868668 PMID:21070844 PMID:21599020 PMID:21724996 PMID:21893697 PMID:22029500 PMID:22039321 PMID:22119283 PMID:22410118 PMID:22849695 PMID:22882778 PMID:23596210 PMID:24038091 PMID:24066068 PMID:24101390 PMID:24316276 PMID:24345466 PMID:24831514 PMID:25079872 PMID:25149976 PMID:25445197 PMID:25472953 PMID:25526689 PMID:25576893 PMID:25740948 PMID:26165751 PMID:30365937 PMID:30503585 PMID:31428839 PMID:31669340 |
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NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
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G |
Mrc1 |
mannose receptor, C type 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MRC1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
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G |
Mrm3 |
mitochondrial rRNA methyltransferase 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MRM3 mRNA |
CTD |
PMID:17982090 |
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NCBI chr10:64,398,308...64,406,193
Ensembl chr10:64,398,339...64,405,017
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G |
Mrpl47 |
mitochondrial ribosomal protein L47 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MRPL47 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 2:119,128,311...119,139,451
Ensembl chr 2:119,128,309...119,139,451
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G |
Msn |
moesin |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MSN mRNA] |
CTD |
PMID:18200517 |
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NCBI chr X:65,226,834...65,294,192
Ensembl chr X:65,226,748...65,295,810
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G |
Muc2 |
mucin 2, oligomeric mucus/gel-forming |
multiple interactions decreases expression increases expression |
EXP ISO |
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA] Trinitrobenzenesulfonic Acid results in decreased expression of MUC2 mRNA |
CTD |
PMID:17449585 PMID:19998380 PMID:25307695 |
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NCBI chr 1:214,663,929...214,693,197
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G |
Muc3 |
mucin 3, intestinal |
increases expression multiple interactions decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA] Trinitrobenzenesulfonic Acid results in decreased expression of MUC3 mRNA |
CTD |
PMID:17375077 PMID:17449585 |
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NCBI chr12:22,535,663...22,584,775
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G |
Muc4 |
mucin 4, cell surface associated |
multiple interactions increases expression |
EXP |
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA] |
CTD |
PMID:15867298 PMID:17449585 |
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NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939
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G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
multiple interactions increases expression |
EXP |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein] Trinitrobenzenesulfonic Acid results in increased expression of MYD88; Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein |
CTD |
PMID:16891783 PMID:19002562 |
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NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
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G |
Naglu |
N-acetyl-alpha-glucosaminidase |
increases secretion |
EXP |
Trinitrobenzenesulfonic Acid results in increased secretion of NAGLU protein |
CTD |
PMID:23307618 |
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NCBI chr10:88,979,363...88,986,879
Ensembl chr10:88,979,383...88,986,867
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G |
Nfe2l2 |
nuclear factor, erythroid 2-like 2 |
multiple interactions decreases expression |
EXP |
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA] |
CTD |
PMID:31428839 PMID:31669340 |
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NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
increases expression multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein] |
CTD |
PMID:26165751 |
|
NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases expression increases degradation |
EXP |
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein] |
CTD |
PMID:15793857 PMID:30365937 |
|
NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
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G |
Ngf |
nerve growth factor |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of NGF mRNA |
CTD |
PMID:17385238 |
|
NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions increases expression |
EXP |
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NLRP3 protein] |
CTD |
PMID:30365937 |
|
NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
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G |
Nmt2 |
N-myristoyltransferase 2 |
decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr17:78,919,235...78,966,013
Ensembl chr17:78,921,793...78,962,476
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G |
Nod2 |
nucleotide-binding oligomerization domain containing 2 |
increases expression |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased expression of NOD2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOD2 protein |
CTD |
PMID:16891783 PMID:22147983 |
|
NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases activity increases expression affects response to substance |
ISO EXP |
Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein] Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein NOS2 protein affects the susceptibility to Trinitrobenzenesulfonic Acid Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Sulfasalazine affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA] |
CTD |
PMID:10845656 PMID:11504810 PMID:11698051 PMID:11717450 PMID:15867298 PMID:17276891 PMID:17375077 PMID:17449036 PMID:17982090 PMID:19238344 PMID:19285099 PMID:20923188 PMID:21893697 PMID:22039321 PMID:24831514 PMID:30365937 PMID:30503585 PMID:31428839 |
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NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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G |
Npy1r |
neuropeptide Y receptor Y1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of NPY1R mRNA |
CTD |
PMID:23537331 |
|
NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of NQO1 mRNA |
CTD |
PMID:19524605 PMID:22609641 PMID:25724174 |
|
NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 protein |
CTD |
PMID:21829567 |
|
NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of NR1I2 mRNA [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid; [Rifaximin binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:21599020 PMID:21829567 |
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NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
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G |
Nr2f1 |
nuclear receptor subfamily 2, group F, member 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of NR2F1 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:5,569,954...5,579,894
Ensembl chr 2:5,569,935...5,579,894
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G |
Nts |
neurotensin |
multiple interactions |
ISO |
NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein] |
CTD |
PMID:25307345 |
|
NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
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G |
Ntsr1 |
neurotensin receptor 1 |
multiple interactions increases response to substance |
ISO |
NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA] NTSR1 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:25307345 |
|
NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
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G |
Nucb2 |
nucleobindin 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of NUCB2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:185,106,773...185,143,278
Ensembl chr 1:185,104,656...185,143,272
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G |
Ocln |
occludin |
multiple interactions decreases expression |
ISO |
Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein] Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein |
CTD |
PMID:22147983 PMID:22849695 PMID:25307695 |
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NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
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G |
Odc1 |
ornithine decarboxylase 1 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of ODC1 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
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G |
Olr1684 |
olfactory receptor 1684 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of OLFR91 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr20:572,454...573,395
Ensembl chr20:572,454...573,395
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G |
Olr1750 |
olfactory receptor 1750 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of OLFR90 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr20:1,944,849...1,955,249
Ensembl chr20:1,944,801...1,945,844
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G |
Oprd1 |
opioid receptor, delta 1 |
multiple interactions increases expression |
EXP |
Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein] Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein |
CTD |
PMID:24637189 |
|
NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
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G |
Oprl1 |
opioid related nociceptin receptor 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of OPRL1 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
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G |
Osmr |
oncostatin M receptor |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OSMR mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 2:56,107,491...56,163,522
Ensembl chr 2:56,110,777...56,151,531
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G |
Otud4 |
OTU deubiquitinase 4 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of OTUD4 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr19:31,895,753...31,942,509
Ensembl chr19:31,899,087...31,942,180
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G |
P2rx7 |
purinergic receptor P2X 7 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of P2RX7 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
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G |
P2ry1 |
purinergic receptor P2Y1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of P2RY1 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
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G |
P2ry13 |
purinergic receptor P2Y13 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of P2RY13 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:149,429,648...149,432,864
Ensembl chr 2:149,430,854...149,432,106
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G |
Pak2 |
p21 (RAC1) activated kinase 2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of PAK2 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of PCK1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
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G |
Pcna |
proliferating cell nuclear antigen |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of PCNA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PCNA protein |
CTD |
PMID:19234664 |
|
NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
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G |
Pdia3 |
protein disulfide isomerase family A, member 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PDIA3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
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G |
Pdpn |
podoplanin |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PDPN mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
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G |
Pecam1 |
platelet and endothelial cell adhesion molecule 1 |
increases expression multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein] |
CTD |
PMID:22410118 |
|
NCBI chr10:94,850,971...94,913,202
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G |
Pgs1 |
phosphatidylglycerophosphate synthase 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PGS1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr10:106,994,595...107,030,208
Ensembl chr10:106,991,935...107,030,260
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G |
Pir |
pirin |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PIR mRNA |
CTD |
PMID:19524605 PMID:22609641 |
|
NCBI chr X:31,852,322...31,968,152
Ensembl chr X:31,852,323...31,968,152
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G |
Pirb |
paired Ig-like receptor B |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LILRB3 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 1:64,074,097...64,081,568
Ensembl chr 1:64,074,231...64,081,438
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G |
Pklr |
pyruvate kinase L/R |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PKLR mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
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G |
Pla2g12a |
phospholipase A2, group XIIA |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PLA2G12A mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:235,311,664...235,327,972
Ensembl chr 2:235,311,719...235,327,972
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G |
Pla2g2a |
phospholipase A2 group IIA |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLA2G2A mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
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G |
Pla2g7 |
phospholipase A2 group VII |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PLA2G7 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
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G |
Plod2 |
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
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G |
Pnliprp1 |
pancreatic lipase-related protein 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PNLIPRP1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:279,867,034...279,882,663
Ensembl chr 1:279,867,034...279,882,663
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G |
Pomc |
proopiomelanocortin |
decreases expression increases expression |
ISO EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of POMC mRNA Trinitrobenzenesulfonic Acid results in increased expression of POMC protein |
CTD |
PMID:11959675 PMID:25307695 |
|
NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions decreases expression |
EXP ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA] Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein |
CTD |
PMID:16782535 PMID:19617644 PMID:21829567 PMID:24831514 PMID:26165751 |
|
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
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G |
Prkci |
protein kinase C, iota |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of PRKCI mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:115,941,998...116,002,550
Ensembl chr 2:115,941,993...116,002,561
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G |
Prss1 |
serine protease 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PRSS1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRY10 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 4:70,776,046...70,779,249
Ensembl chr 4:70,776,046...70,779,249
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G |
Prss3 |
serine protease 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PRSS3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 4:70,614,524...70,617,998
Ensembl chr 4:70,614,524...70,617,998
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G |
Psme3 |
proteasome activator subunit 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PSME3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr10:89,236,256...89,244,041
Ensembl chr10:89,236,256...89,244,041
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|
G |
Ptger2 |
prostaglandin E receptor 2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of PTGER2 mRNA |
CTD |
PMID:23537331 PMID:25526689 |
|
NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
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G |
Ptger4 |
prostaglandin E receptor 4 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of PTGER4 mRNA |
CTD |
PMID:25526689 |
|
NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
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G |
Ptges |
prostaglandin E synthase |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of PTGES mRNA |
CTD |
PMID:25526689 |
|
NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
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G |
Ptgir |
prostaglandin I2 receptor |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of PTGIR mRNA |
CTD |
PMID:25526689 |
|
NCBI chr 1:78,833,449...78,835,832
Ensembl chr 1:78,833,157...78,837,623
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G |
Ptgis |
prostaglandin I2 synthase |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of PTGIS mRNA |
CTD |
PMID:25526689 |
|
NCBI chr 3:163,950,746...163,986,129
|
|
G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of PTGS1 mRNA |
CTD |
PMID:25526689 |
|
NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
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|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions decreases expression increases expression |
ISO EXP |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein] Trinitrobenzenesulfonic Acid results in decreased expression of PTGS2 mRNA Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein Trinitrobenzenesulfonic Acid results in increased expression of PTGS2; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA] |
CTD |
PMID:11137876 PMID:11698051 PMID:11717450 PMID:11820457 PMID:15973123 PMID:16474422 PMID:16782535 PMID:16804969 PMID:17276891 PMID:17375077 PMID:17375199 PMID:18200517 PMID:19234664 PMID:19956958 PMID:20923188 PMID:21513799 PMID:21893697 PMID:22039321 PMID:24316276 PMID:24831514 PMID:25307695 PMID:25526689 PMID:25576893 PMID:30365937 |
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NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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Ptprc |
protein tyrosine phosphatase, receptor type, C |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PTPRC mRNA |
CTD |
PMID:17982090 |
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NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
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Ptpro |
protein tyrosine phosphatase, receptor type, O |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTPRO mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677
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Ptx3 |
pentraxin 3 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
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Rab10 |
RAB10, member RAS oncogene family |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of RAB10 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 6:27,668,387...27,721,120
Ensembl chr 6:27,668,403...27,721,120
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Rab15 |
RAB15, member RAS oncogene family |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of RAB15 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 6:99,845,952...99,870,320
Ensembl chr 6:99,845,954...99,870,024
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Rab39a |
RAB39A, member RAS oncogene family |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of RAB39A mRNA |
CTD |
PMID:23537331 |
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NCBI chr 8:58,275,984...58,292,995
Ensembl chr 8:58,272,098...58,293,102
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Rab5a |
RAB5A, member RAS oncogene family |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of RAB5A mRNA |
CTD |
PMID:23537331 |
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NCBI chr 9:5,910...6,065
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Ramp2 |
receptor activity modifying protein 2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of RAMP2 mRNA |
CTD |
PMID:21808981 |
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NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
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Ramp3 |
receptor activity modifying protein 3 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of RAMP3 mRNA |
CTD |
PMID:21808981 |
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NCBI chr14:86,922,223...86,939,722
Ensembl chr14:86,922,223...86,939,719
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Rap1b |
RAP1B, member of RAS oncogene family |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of RAP1B mRNA |
CTD |
PMID:23537331 |
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NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990
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Rasa2 |
RAS p21 protein activator 2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of RASA2 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 8:104,417,827...104,542,313
Ensembl chr 8:104,414,567...104,542,317
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Rasa3 |
RAS p21 protein activator 3 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of RASA3 mRNA |
CTD |
PMID:23537331 |
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NCBI chr16:81,320,090...81,434,239
Ensembl chr16:81,318,633...81,434,363
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Rasd2 |
RASD family, member 2 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of RASD2 mRNA |
CTD |
PMID:23537331 |
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NCBI chr19:14,653,198...14,663,914
Ensembl chr19:14,653,198...14,663,914
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Rbp1 |
retinol binding protein 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RBP1 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842
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Reg3b |
regenerating family member 3 beta |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of REG3B mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
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Reg3g |
regenerating family member 3 gamma |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3G mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234
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Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases expression increases phosphorylation affects localization |
EXP ISO |
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid affects the localization of RELA protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein] Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of RELA protein Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein] |
CTD |
PMID:16474422 PMID:19597321 PMID:19956958 PMID:21070844 PMID:22410118 PMID:24831514 |
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NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
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Retnlb |
resistin like beta |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA] |
CTD |
PMID:18200517 |
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NCBI chr11:54,565,471...54,567,578
Ensembl chr11:54,565,472...54,567,357
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Rhoq |
ras homolog family member Q |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of RHOQ mRNA |
CTD |
PMID:23537331 |
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NCBI chr 6:10,533,151...10,568,582
Ensembl chr 6:10,533,151...10,568,581
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Rmnd1 |
required for meiotic nuclear division 1 homolog |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of RMND1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:40,948,843...40,982,669
Ensembl chr 1:40,948,847...40,972,826
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Rnase1l1 |
ribonuclease, RNase A family, 1-like 1 (pancreatic) |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RNASE1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr15:28,043,491...28,045,098
Ensembl chr15:28,043,758...28,044,210
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Rngtt |
RNA guanylyltransferase and 5'-phosphatase |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RNGTT mRNA |
CTD |
PMID:17982090 |
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NCBI chr 5:48,561,325...48,779,214
Ensembl chr 5:48,561,339...48,779,207
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Rprm |
reprimo, TP53 dependent G2 arrest mediator homolog |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of RPRM mRNA |
CTD |
PMID:17982090 |
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NCBI chr 3:39,595,301...39,596,718
Ensembl chr 3:39,595,301...39,596,718
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G |
Rreb1 |
ras responsive element binding protein 1 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of RREB1 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr17:27,539,137...27,718,878
Ensembl chr17:27,539,133...27,665,266
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G |
RT1-Ba |
RT1 class II, locus Ba |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of H2-AA mRNA |
CTD |
PMID:17982090 |
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NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
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RT1-Da |
RT1 class II, locus Da |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of H2-EA mRNA |
CTD |
PMID:17982090 |
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NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
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Ryr1 |
ryanodine receptor 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of RYR1 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
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G |
S100a8 |
S100 calcium binding protein A8 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A8 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
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G |
S100a9 |
S100 calcium binding protein A9 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A9 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
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G |
Sat1 |
spermidine/spermine N1-acetyl transferase 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of SAT1 mRNA |
CTD |
PMID:12163651 |
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NCBI chr X:43,626,480...43,629,767
Ensembl chr X:43,625,169...43,629,765
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G |
Scd |
stearoyl-CoA desaturase |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SCD1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
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G |
Scn10a |
sodium voltage-gated channel alpha subunit 10 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SCN10A |
CTD |
PMID:15205116 |
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NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
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G |
Selenow |
selenoprotein W |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SELENOW mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:77,530,692...77,535,765
Ensembl chr 1:77,533,148...77,535,681 Ensembl chr 1:77,533,148...77,535,681
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G |
Serpina3m |
serpin family A member 3M |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SERPINA3 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINA3 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
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G |
Serpinb5 |
serpin family B member 5 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SERPINB5 mRNA |
CTD |
PMID:17982090 |
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NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
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G |
Serpine2 |
serpin family E member 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINE2 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
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Shbg |
sex hormone binding globulin |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SHBG mRNA |
CTD |
PMID:17982090 |
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NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
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G |
Sirt1 |
sirtuin 1 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of SIRT1 protein |
CTD |
PMID:24782617 |
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NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
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G |
Slc10a1 |
solute carrier family 10 member 1 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 protein |
CTD |
PMID:12044520 |
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NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
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G |
Slc1a1 |
solute carrier family 1 member 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SLC1A1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056
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G |
Slc20a1 |
solute carrier family 20 member 1 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC20A1 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 3:121,725,204...121,739,160
Ensembl chr 3:121,725,859...121,739,173
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Slc26a2 |
solute carrier family 26 member 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SLC26A2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr18:56,518,999...56,534,539
Ensembl chr18:56,520,740...56,534,415
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Slc30a10 |
solute carrier family 30, member 10 |
decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr13:103,396,295...103,406,759
Ensembl chr13:103,396,314...103,410,363
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Slc4a4 |
solute carrier family 4 member 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SLC4A4 mRNA |
CTD |
PMID:17982090 |
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NCBI chr14:20,476,258...20,817,042
Ensembl chr14:20,479,323...20,920,286
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G |
Slco1a4 |
solute carrier organic anion transporter family, member 1a4 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 protein |
CTD |
PMID:12044520 |
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NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
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G |
Slco1b2 |
solute carrier organic anion transporter family member 1B2 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1B2 mRNA |
CTD |
PMID:12044520 |
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NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
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G |
Slfn4 |
schlafen family member 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SLFN4 mRNA |
CTD |
PMID:17982090 |
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NCBI chr10:70,411,686...70,435,162
Ensembl chr10:70,411,738...70,435,156
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G |
Slpi |
secretory leukocyte peptidase inhibitor |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SLPI mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
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G |
Smc2 |
structural maintenance of chromosomes 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SMC2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 5:68,717,509...68,764,080
Ensembl chr 5:68,717,519...68,763,850
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G |
Smpx |
small muscle protein, X-linked |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SMPX mRNA] |
CTD |
PMID:18200517 |
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NCBI chr X:40,029,200...40,086,870
Ensembl chr X:40,030,248...40,086,870
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G |
Sparc |
secreted protein acidic and cysteine rich |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Indomethacin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Tretinoin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA] |
CTD |
PMID:17994277 PMID:18200517 |
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NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
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G |
Spp1 |
secreted phosphoprotein 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SPP1 mRNA Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene] |
CTD |
PMID:14555839 PMID:17982090 |
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NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
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G |
Srgn |
serglycin |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SRGN mRNA |
CTD |
PMID:17982090 |
|
NCBI chr20:32,120,317...32,158,071
Ensembl chr20:32,120,320...32,139,789
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G |
Srm |
spermidine synthase |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SRM mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
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G |
Stat1 |
signal transducer and activator of transcription 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of STAT1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
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G |
Stat3 |
signal transducer and activator of transcription 3 |
increases phosphorylation multiple interactions |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:25740948 PMID:30365937 |
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NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
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G |
Stim1 |
stromal interaction molecule 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of STIM1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:167,373,894...167,533,412
Ensembl chr 1:167,373,678...167,533,420
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G |
Stk17b |
serine/threonine kinase 17b |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of STK17B mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 9:60,399,261...60,430,081
Ensembl chr 9:60,399,261...60,430,081
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G |
Sulf2 |
sulfatase 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SULF2 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
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G |
Tac1 |
tachykinin, precursor 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TAC1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
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G |
Tacr1 |
tachykinin receptor 1 |
multiple interactions affects response to substance |
ISO |
TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA] TACR1 protein affects the susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:20889569 |
|
NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
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G |
Tff3 |
trefoil factor 3 |
multiple interactions increases expression |
EXP |
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA] |
CTD |
PMID:15867298 PMID:17449585 |
|
NCBI chr20:9,850,800...9,855,481
Ensembl chr20:9,850,803...9,855,481
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions increases expression decreases expression |
ISO |
6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of TGFB1 protein; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein] Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein Trinitrobenzenesulfonic Acid results in decreased expression of TGFB1 mRNA |
CTD |
PMID:20889569 PMID:21599020 PMID:25307695 PMID:25740948 |
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NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
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G |
Tgfb2 |
transforming growth factor, beta 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TGFB2 mRNA |
CTD |
PMID:25307695 |
|
NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
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G |
Tgfbr1 |
transforming growth factor, beta receptor 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of TGFBR1 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
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G |
Tgm2 |
transglutaminase 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGM2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
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G |
Tgm3 |
transglutaminase 3 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TGM3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 3:122,544,783...122,580,836
Ensembl chr 3:122,544,788...122,580,905
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G |
Thbd |
thrombomodulin |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of THBD mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
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G |
Thbs1 |
thrombospondin 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THBS1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
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G |
Thy1 |
Thy-1 cell surface antigen |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 8:48,382,121...48,387,271
Ensembl chr 8:48,382,121...48,386,935
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
ISO EXP |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]; ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein] |
CTD |
PMID:17982090 PMID:18200517 PMID:18837084 |
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NCBI chr X:1,364,771...1,369,451
Ensembl chr X:1,364,786...1,369,384
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G |
Tjp1 |
tight junction protein 1 |
multiple interactions decreases expression |
ISO |
ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein] Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein |
CTD |
PMID:22147983 PMID:22849695 |
|
NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
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G |
Tjp2 |
tight junction protein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TJP2 mRNA |
CTD |
PMID:25307695 |
|
NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484
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G |
Tlr2 |
toll-like receptor 2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of TLR2 |
CTD |
PMID:16891783 |
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NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions increases expression decreases expression |
ISO EXP |
lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein] Trinitrobenzenesulfonic Acid results in increased expression of TLR4; Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein Trinitrobenzenesulfonic Acid results in decreased expression of TLR4 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein] |
CTD |
PMID:16891783 PMID:19002562 PMID:19597321 PMID:19956958 PMID:19998380 PMID:20136961 |
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NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
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G |
Tmem245 |
transmembrane protein 245 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of TMEM245 mRNA |
CTD |
PMID:12163651 |
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NCBI chr 5:73,909,032...73,986,602
Ensembl chr 5:73,918,747...73,986,373
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G |
Tnc |
tenascin C |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNC mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression increases secretion |
ISO EXP |
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] Trinitrobenzenesulfonic Acid results in increased expression of TNF; Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TNF protein Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; iberogast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] |
CTD |
PMID:11717450 PMID:12717850 PMID:16474422 PMID:16782535 PMID:16867261 PMID:17276891 PMID:17375199 PMID:17449585 PMID:18200517 PMID:19196500 PMID:19285099 PMID:19597321 PMID:19956958 PMID:19998380 PMID:20136961 PMID:20868668 PMID:20923188 PMID:21070844 PMID:21122500 PMID:21513799 PMID:21599020 PMID:21829567 PMID:21893697 PMID:22039321 PMID:22060784 PMID:22119283 PMID:22147983 PMID:22410118 PMID:22427801 PMID:23027085 PMID:23537331 PMID:23596210 PMID:23747339 PMID:24066068 PMID:24316276 PMID:24831514 PMID:25472953 PMID:25576893 PMID:25727887 PMID:25729217 PMID:27783946 PMID:30503585 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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G |
Tnfrsf25 |
TNF receptor superfamily member 25 |
increases response to substance |
ISO |
TNFRSF25 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:20980995 |
|
NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
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G |
Tnfsf11 |
TNF superfamily member 11 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TNFSF11 protein |
CTD |
PMID:23747339 |
|
NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
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G |
Tnfsf15 |
TNF superfamily member 15 |
increases response to substance |
ISO |
TNFSF15 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:20980995 |
|
NCBI chr 5:79,553,935...79,569,974
Ensembl chr 5:79,553,742...79,570,073
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G |
Tnfsf4 |
TNF superfamily member 4 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of TNFSF4 mRNA |
CTD |
PMID:23537331 |
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NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
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G |
Tp53 |
tumor protein p53 |
multiple interactions increases expression |
ISO EXP |
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of TRP53 protein] Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein Trinitrobenzenesulfonic Acid results in increased expression of TRP53 protein |
CTD |
PMID:22427801 PMID:30503585 |
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NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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G |
Trim15 |
tripartite motif containing 15 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIM15 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr20:2,194,293...2,203,636
Ensembl chr20:2,194,709...2,201,668
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G |
Trim16 |
tripartite motif-containing 16 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TRIM16 mRNA |
CTD |
PMID:19524605 PMID:22609641 |
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NCBI chr10:49,231,660...49,254,653
Ensembl chr10:49,231,730...49,254,621
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G |
Trip4 |
thyroid hormone receptor interactor 4 |
increases expression multiple interactions |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein] |
CTD |
PMID:30365937 |
|
NCBI chr 8:71,369,121...71,533,281
Ensembl chr 8:71,371,370...71,533,459
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G |
Trpc3 |
transient receptor potential cation channel, subfamily C, member 3 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of TRPC3 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:123,329,954...123,467,574
Ensembl chr 2:123,329,875...123,407,496
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G |
Trpm8 |
transient receptor potential cation channel, subfamily M, member 8 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TRPM8 mRNA |
CTD |
PMID:23596210 |
|
NCBI chr 9:95,393,370...95,484,528
Ensembl chr 9:95,398,237...95,482,890
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions increases expression decreases expression |
EXP |
topiramate inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV1 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 protein |
CTD |
PMID:17698068 PMID:17991707 PMID:21849664 PMID:25445197 |
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NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
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G |
Trpv4 |
transient receptor potential cation channel, subfamily V, member 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TRPV4 mRNA |
CTD |
PMID:22882778 |
|
NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
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G |
Trpv5 |
transient receptor potential cation channel, subfamily V, member 5 |
multiple interactions |
ISO |
KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein]; Trinitrobenzenesulfonic Acid results in decreased expression of and results in increased metabolism of TRPV5 protein |
CTD |
PMID:23747339 |
|
NCBI chr 4:70,947,615...70,974,004
Ensembl chr 4:70,947,717...70,974,006
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G |
Txndc16 |
thioredoxin domain containing 16 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TXNDC16 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr15:19,472,522...19,547,384
Ensembl chr15:19,473,373...19,541,815
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G |
Tyrobp |
transmembrane immune signaling adaptor Tyrobp |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TYROBP mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303
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G |
Ubc |
ubiquitin C |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of UBC mRNA |
CTD |
PMID:12163651 |
|
NCBI chr12:36,638,457...36,642,734
Ensembl chr12:36,638,457...36,642,734
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G |
Ubd |
ubiquitin D |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of UBD mRNA |
CTD |
PMID:17982090 |
|
NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
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G |
Ube2w |
ubiquitin-conjugating enzyme E2W |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of UBE2W mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 5:29,798,845...29,812,777
|
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G |
Ugt1a6 |
UDP glucuronosyltransferase family 1 member A6 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of UGT1A6 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
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G |
Usp8 |
ubiquitin specific peptidase 8 |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of USP8 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 3:119,173,818...119,222,499
Ensembl chr 3:119,173,818...119,222,484
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
increases expression multiple interactions |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein |
CTD |
PMID:17982090 PMID:22029500 PMID:30503585 |
|
NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
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G |
Vcan |
versican |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAN mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 2:18,490,102...18,587,340
Ensembl chr 2:18,490,102...18,565,842
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases expression |
EXP ISO |
Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA] NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA] |
CTD |
PMID:21893697 PMID:25307345 |
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NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
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G |
Vim |
vimentin |
multiple interactions increases expression |
ISO |
6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA] |
CTD |
PMID:20889569 |
|
NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
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G |
Vnn1 |
vanin 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of VNN1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VNN1 protein |
CTD |
PMID:23307618 |
|
NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
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G |
Vwf |
von Willebrand factor |
multiple interactions increases expression |
ISO |
NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein] |
CTD |
PMID:25307345 |
|
NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
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G |
Wdr48 |
WD repeat domain 48 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of WDR48 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 8:128,577,080...128,610,287
Ensembl chr 8:128,577,080...128,610,287
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G |
Wfdc18 |
WAP four-disulfide core domain 18 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of WFDC18 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr10:71,008,709...71,010,863
Ensembl chr10:71,008,709...71,010,863
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G |
Zc3h11a |
zinc finger CCCH-type containing 11A |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of ZC3H11A mRNA |
CTD |
PMID:17982090 |
|
NCBI chr13:50,196,042...50,234,862
Ensembl chr13:50,196,042...50,234,862
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G |
Zfp36l2 |
zinc finger protein 36, C3H type-like 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ZFP36L2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:7,417,416...7,423,447
Ensembl chr 6:7,417,425...7,421,456
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G |
Ada |
adenosine deaminase |
increases expression |
EXP |
2,4-dinitrobenzenesulfonic acid results in increased expression of ADA mRNA |
CTD |
PMID:20860664 |
|
NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
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G |
Adarb1 |
adenosine deaminase, RNA-specific, B1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of ADARB1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr20:11,972,352...12,101,022
Ensembl chr20:11,972,381...12,101,047
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G |
Adora3 |
adenosine A3 receptor |
increases expression |
EXP |
2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 mRNA; 2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 protein |
CTD |
PMID:20860664 |
|
NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
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G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of ATF3 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
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G |
Bnip3 |
BCL2 interacting protein 3 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of BNIP3 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
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G |
Caly |
calcyon neuron-specific vesicular protein |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of CALY mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 1:212,537,851...212,549,040
Ensembl chr 1:212,537,848...212,549,477
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of CCL7 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of CCR2 mRNA |
CTD |
PMID:30116771 |
|
|
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G |
Cdh4 |
cadherin 4 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of CDH4 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 3:175,220,520...175,283,144
Ensembl chr 3:175,144,495...175,279,761
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G |
Ciapin1 |
cytokine induced apoptosis inhibitor 1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of CIAPIN1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr19:10,596,923...10,612,414
Ensembl chr19:10,596,960...10,610,049
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G |
Cnr1 |
cannabinoid receptor 1 |
decreases response to substance |
ISO |
CNR1 results in decreased susceptibility to 2,4-dinitrobenzenesulfonic acid |
CTD |
PMID:15085199 |
|
NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
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G |
Creb1 |
cAMP responsive element binding protein 1 |
affects expression |
ISO |
2,4-dinitrobenzenesulfonic acid affects the expression of CREB1 mRNA |
CTD |
PMID:20385217 |
|
NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
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G |
Crlf1 |
cytokine receptor-like factor 1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of CRLF1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr16:20,675,042...20,686,365
Ensembl chr16:20,675,042...20,686,317
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G |
Ctnna3 |
catenin alpha 3 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of CTNNA3 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr20:25,063,124...26,640,428
Ensembl chr20:26,516,836...26,589,209
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of CXCL1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
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G |
Dlc1 |
DLC1 Rho GTPase activating protein |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of DLC1 mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of DLC1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr16:58,776,489...59,247,752
Ensembl chr16:59,077,574...59,247,754
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G |
Faah |
fatty acid amide hydrolase |
increases response to substance |
ISO |
FAAH results in increased susceptibility to 2,4-dinitrobenzenesulfonic acid |
CTD |
PMID:15085199 |
|
NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775
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G |
Faahl |
fatty-acid amide hydrolase-like |
increases response to substance |
ISO |
FAAH results in increased susceptibility to 2,4-dinitrobenzenesulfonic acid |
CTD |
PMID:15085199 |
|
NCBI chr 5:134,330,204...134,349,400
Ensembl chr 5:134,331,929...134,348,995
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G |
Fat4 |
FAT atypical cadherin 4 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of FAT4 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 2:125,751,818...125,879,398
Ensembl chr 2:125,752,130...125,879,387
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G |
Fhl2 |
four and a half LIM domains 2 |
multiple interactions |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of FHL2 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
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G |
Fhl3 |
four and a half LIM domains 3 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of FHL3 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 5:142,688,962...142,696,330
Ensembl chr 5:142,689,026...142,696,383
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G |
Gcnt2 |
glucosaminyl (N-acetyl) transferase 2 (I blood group) |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of GCNT2 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr17:21,634,546...21,677,477
Ensembl chr17:21,634,551...21,739,408
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G |
Gfap |
glial fibrillary acidic protein |
increases expression multiple interactions |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA] |
CTD |
PMID:30116771 |
|
NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
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G |
Igf1r |
insulin-like growth factor 1 receptor |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of IGF1R mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
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G |
Il10ra |
interleukin 10 receptor subunit alpha |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of IL10RA mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
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G |
Il6 |
interleukin 6 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of IL6 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
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G |
Itpk1 |
inositol-tetrakisphosphate 1-kinase |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of ITPK1 mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of ITPK1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 6:126,448,920...126,582,188
Ensembl chr 6:126,450,139...126,582,134
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G |
Jaml |
junction adhesion molecule like |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of JAML mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 8:49,378,644...49,408,894
Ensembl chr 8:49,378,644...49,410,088
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G |
Kalrn |
kalirin, RhoGEF kinase |
increases expression multiple interactions |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of KALRN mRNA [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KALRN mRNA |
CTD |
PMID:30116771 |
|
NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
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G |
Kcnb2 |
potassium voltage-gated channel subfamily B member 2 |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KCNB2 mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of KCNB2 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 5:2,975,934...3,430,837
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G |
Lif |
LIF, interleukin 6 family cytokine |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of LIF mRNA |
CTD |
PMID:30116771 |
|
NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
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G |
Mfsd6 |
major facilitator superfamily domain containing 6 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of MFSD6 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 9:53,626,412...53,710,820
Ensembl chr 9:53,626,592...53,710,817
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G |
Msh2 |
mutS homolog 2 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of MSH2 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
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G |
Nfix |
nuclear factor I X |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of NFIX mRNA |
CTD |
PMID:30116771 |
|
NCBI chr19:25,818,640...25,914,777
Ensembl chr19:25,821,780...25,914,696
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
affects expression |
ISO |
2,4-dinitrobenzenesulfonic acid affects the expression of NFKB1 mRNA |
CTD |
PMID:20385217 |
|
NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
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G |
Nt5e |
5' nucleotidase, ecto |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of NT5E mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of NT5E mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
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G |
Odc1 |
ornithine decarboxylase 1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of ODC1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
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G |
Oprk1 |
opioid receptor, kappa 1 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of OPRK1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
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G |
Pde4d |
phosphodiesterase 4D |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PDE4D mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of PDE4D mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
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G |
Pik3c2a |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of PIK3C2A mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 1:185,210,922...185,326,314
Ensembl chr 1:185,210,922...185,326,314
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G |
Psmb8 |
proteasome 20S subunit beta 8 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of PSMB8 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr20:3,990,809...3,993,772
Ensembl chr20:3,990,613...3,993,769
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G |
Ptger4 |
prostaglandin E receptor 4 |
decreases expression multiple interactions |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of PTGER4 mRNA [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PTGER4 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
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G |
Rps15a |
ribosomal protein S15a |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of RPS15A mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 1:187,759,865...187,766,734
Ensembl chr 1:187,759,480...187,766,709
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G |
RT1-Ba |
RT1 class II, locus Ba |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-AA mRNA |
CTD |
PMID:30116771 |
|
NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
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G |
RT1-S3 |
RT1 class Ib, locus S3 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-T23 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
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G |
Sgcd |
sarcoglycan, delta |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of SGCD mRNA |
CTD |
PMID:30116771 |
|
NCBI chr10:32,062,946...32,471,454
Ensembl chr10:32,062,946...32,471,454
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G |
Slc9a1 |
solute carrier family 9 member A1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of SLC9A1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
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G |
Tac1 |
tachykinin, precursor 1 |
multiple interactions increases expression |
ISO |
GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of TAC1 mRNA] |
CTD |
PMID:30116771 |
|
NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
|
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G |
Tacr2 |
tachykinin receptor 2 |
multiple interactions |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in decreased expression of TACR2 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr20:31,892,515...31,905,153
Ensembl chr20:31,892,515...31,905,153
|
|
G |
Taf1b |
TATA-box binding protein associated factor, RNA polymerase I subunit B |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of TAF1B mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of TAF1B mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 6:43,644,931...43,722,124
Ensembl chr 6:43,644,830...43,722,113
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G |
Tapbpl |
TAP binding protein-like |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of TAPBPL mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 4:157,735,748...157,743,199
Ensembl chr 4:157,735,748...157,743,199
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G |
Thbs1 |
thrombospondin 1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of THBS1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
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|
G |
Tnf |
tumor necrosis factor |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of TNF mRNA |
CTD |
PMID:20385217 |
|
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
|
|
G |
Trim62 |
tripartite motif-containing 62 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of TRIM62 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 5:147,068,725...147,099,024
Ensembl chr 5:147,069,616...147,095,242
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|
G |
Vti1a |
vesicle transport through interaction with t-SNAREs 1A |
increases expression multiple interactions |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of VTI1A mRNA [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of VTI1A mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 1:276,310,072...276,508,635
Ensembl chr 1:276,309,927...276,490,602
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|
|
G |
Cat |
catalase |
decreases activity |
EXP |
metanil yellow results in decreased activity of CAT protein |
CTD |
PMID:26494366 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
|
|
G |
Ccnb1 |
cyclin B1 |
multiple interactions |
EXP |
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 protein |
CTD |
PMID:12616621 |
|
NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
|
|
G |
Ccnd1 |
cyclin D1 |
increases expression multiple interactions |
EXP |
metanil yellow results in increased expression of CCND1 protein [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCND1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCND1 protein; metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein] |
CTD |
PMID:10906429 PMID:12616621 |
|
NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
|
|
G |
Ccne1 |
cyclin E1 |
multiple interactions increases expression |
EXP |
metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of CCNE1 protein] metanil yellow results in increased expression of CCNE1 protein |
CTD |
PMID:10906429 |
|
NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
|
|
G |
Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions |
EXP |
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK1 protein |
CTD |
PMID:12616621 |
|
NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
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|
G |
Cdk4 |
cyclin-dependent kinase 4 |
multiple interactions |
EXP |
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 protein |
CTD |
PMID:12616621 |
|
NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
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|
G |
Fshb |
follicle stimulating hormone subunit beta |
decreases expression |
EXP |
metanil yellow results in decreased expression of FSHB |
CTD |
PMID:26494366 |
|
NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
|
|
G |
Gsr |
glutathione-disulfide reductase |
decreases activity |
EXP |
metanil yellow results in decreased activity of GSR protein |
CTD |
PMID:26494366 |
|
NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
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|
G |
Lhb |
luteinizing hormone subunit beta |
decreases expression |
EXP |
metanil yellow results in decreased expression of LHB |
CTD |
PMID:26494366 |
|
NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
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|
G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions increases expression |
EXP |
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of PCNA protein; metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of PCNA protein] metanil yellow results in increased expression of PCNA protein |
CTD |
PMID:10906429 PMID:11831363 PMID:12616621 |
|
NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
|
|
|
G |
Aicda |
activation-induced cytidine deaminase |
increases response to substance multiple interactions |
ISO |
AICDA results in increased susceptibility to 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid [4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein] which results in increased activity of AICDA protein |
CTD |
PMID:23589568 |
|
NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
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|
G |
Alb |
albumin |
decreases uptake |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased uptake of ALB protein |
CTD |
PMID:16313995 |
|
NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
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|
G |
Ano6 |
anoctamin 6 |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of ANO6 protein |
CTD |
PMID:24478309 |
|
NCBI chr 7:137,142,063...137,335,208
Ensembl chr 7:137,142,170...137,335,208
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|
G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of ATF4 protein] |
CTD |
PMID:27638049 |
|
NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
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|
G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased cleavage of CASP3 protein]; [Carmustine co-treated with 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid] results in increased activity of CASP3 protein |
CTD |
PMID:18590702 PMID:28343033 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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|
G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased cleavage of CASP9 protein] |
CTD |
PMID:14766669 PMID:28343033 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
|
|
G |
Cftr |
CF transmembrane conductance regulator |
multiple interactions decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Colforsin results in increased activity of CFTR protein] 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CFTR protein |
CTD |
PMID:15131065 PMID:16038730 |
|
NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
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|
G |
Clcn3 |
chloride voltage-gated channel 3 |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLCN3 protein |
CTD |
PMID:17699636 |
|
NCBI chr16:32,448,821...32,520,649
Ensembl chr16:32,449,116...32,519,148
|
|
G |
Clcnka |
chloride voltage-gated channel Ka |
decreases activity |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid analog results in decreased activity of CLCNKA protein |
CTD |
PMID:15167890 |
|
NCBI chr 5:159,931,497...159,946,483
Ensembl chr 5:159,931,511...159,946,446
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|
G |
Clcnkb |
chloride voltage-gated channel Kb |
decreases activity |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid analog results in decreased activity of CLCNKB protein |
CTD |
PMID:15167890 |
|
NCBI chr 5:159,950,384...159,973,576
Ensembl chr 5:159,950,392...159,962,676
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G |
Clic1 |
chloride intracellular channel 1 |
multiple interactions |
ISO |
[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLIC1 protein] which results in increased susceptibility to Carmustine |
CTD |
PMID:18590702 |
|
NCBI chr20:5,040,314...5,049,166
Ensembl chr20:5,040,337...5,049,166
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|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of DDIT3 protein] 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of DDIT3 protein] |
CTD |
PMID:27638049 PMID:29421517 |
|
NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
|
|
G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of EIF2AK3 protein modified form] |
CTD |
PMID:27638049 |
|
NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
|
|
G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:27638049 |
|
NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of HSPA5 protein] |
CTD |
PMID:29421517 |
|
NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
|
|
G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] |
CTD |
PMID:11907163 |
|
NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
|
|
G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] |
CTD |
PMID:11907163 |
|
NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
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|
G |
Il1b |
interleukin 1 beta |
affects secretion multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid affects the secretion of IL1B protein 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in decreased expression of IL1B mRNA] |
CTD |
PMID:15578659 PMID:27461142 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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|
G |
Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of ITPR1 protein modified form] |
CTD |
PMID:27638049 |
|
NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein] |
CTD |
PMID:19815690 |
|
NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
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|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK9 protein] |
CTD |
PMID:19815690 |
|
NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
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|
G |
Panx1 |
Pannexin 1 |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of PANX1 protein |
CTD |
PMID:19023039 |
|
NCBI chr 8:13,567,185...13,606,040
Ensembl chr 8:13,566,739...13,606,040
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form] |
CTD |
PMID:28343033 |
|
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
|
|
G |
Pdcd6ip |
programmed cell death 6 interacting protein |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in decreased expression of PDCD6IP protein] |
CTD |
PMID:29421517 |
|
NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125
|
|
G |
Rad51 |
RAD51 recombinase |
decreases activity multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein [4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein] which results in increased activity of AICDA protein |
CTD |
PMID:23589568 |
|
NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
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G |
Rara |
retinoic acid receptor, alpha |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased degradation of RARA protein] |
CTD |
PMID:17018029 |
|
NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
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|
G |
Sct |
secretin |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SCT protein |
CTD |
PMID:10880878 |
|
NCBI chr 1:214,264,865...214,277,437
Ensembl chr 1:214,264,754...214,265,668
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|
G |
Slc12a7 |
solute carrier family 12 member 7 |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC12A7 protein |
CTD |
PMID:10913127 |
|
NCBI chr 1:32,086,755...32,167,950
Ensembl chr 1:32,086,755...32,141,036
|
|
G |
Slc19a1 |
solute carrier family 19 member 1 |
multiple interactions |
ISO |
[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC19A1 protein] which results in decreased uptake of Folic Acid |
CTD |
PMID:17034785 |
|
NCBI chr20:12,334,675...12,354,517
Ensembl chr20:12,334,676...12,352,377
|
|
G |
Slc22a6 |
solute carrier family 22 member 6 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] |
CTD |
PMID:12472777 |
|
NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
|
|
G |
Slc46a1 |
solute carrier family 46 member 1 |
multiple interactions decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC46A1 protein results in increased transport of Folic Acid] 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC46A1 protein |
CTD |
PMID:17475902 |
|
NCBI chr10:65,728,508...65,741,708
Ensembl chr10:65,733,991...65,740,828
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|
G |
Slc4a1 |
solute carrier family 4 member 1 (Diego blood group) |
multiple interactions affects binding |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC4A1 protein results in increased transport of Chlorides] 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid binds to SLC4A1 protein |
CTD |
PMID:2511191 |
|
NCBI chr10:90,296,144...90,312,401
Ensembl chr10:90,296,141...90,312,386
|
|
G |
Slc4a2 |
solute carrier family 4 member 2 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC4A2 protein results in increased uptake of Benzoic Acid] |
CTD |
PMID:9563070 |
|
NCBI chr 4:7,264,677...7,282,355
Ensembl chr 4:7,264,683...7,281,223
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|
G |
Slc4a4 |
solute carrier family 4 member 4 |
decreases activity |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC4A4 protein |
CTD |
PMID:17325238 |
|
NCBI chr14:20,476,258...20,817,042
Ensembl chr14:20,479,323...20,920,286
|
|
G |
Slc5a5 |
solute carrier family 5 member 5 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] |
CTD |
PMID:12541134 |
|
NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
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|
G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of SQSTM1 protein] |
CTD |
PMID:29421517 |
|
NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
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|
G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in decreased expression of TGFB1 mRNA] |
CTD |
PMID:27461142 |
|
NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
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|
G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein] |
CTD |
PMID:10951577 |
|
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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|
G |
Vdac1 |
voltage-dependent anion channel 1 |
multiple interactions |
EXP ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Staurosporine promotes the reaction [VDAC1 protein binds to VDAC1 protein]] 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone promotes the reaction [VDAC1 protein binds to VDAC1 protein]] |
CTD |
PMID:20937774 PMID:28343033 |
|
NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
|
|
G |
Vdac2 |
voltage-dependent anion channel 2 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone promotes the reaction [VDAC2 protein binds to VDAC2 protein]] |
CTD |
PMID:29229420 |
|
NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
|
|
|
G |
Slc4a1 |
solute carrier family 4 member 1 (Diego blood group) |
multiple interactions |
ISO |
4,4'-dinitro-2,2'-stilbenedisulfonic acid inhibits the reaction [SLC4A1 protein results in increased transport of Chlorides] |
CTD |
PMID:2511191 |
|
NCBI chr10:90,296,144...90,312,401
Ensembl chr10:90,296,141...90,312,386
|
|
|
G |
Avp |
arginine vasopressin |
multiple interactions |
EXP |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of AVP protein] |
CTD |
PMID:11102496 |
|
NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
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|
G |
Fn1 |
fibronectin 1 |
decreases expression |
ISO |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid results in decreased expression of FN1 mRNA |
CTD |
PMID:18210741 |
|
NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Silicon Dioxide analog results in increased expression of IL6 protein] |
CTD |
PMID:24793913 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Nox1 |
NADPH oxidase 1 |
multiple interactions |
ISO |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] |
CTD |
PMID:24912985 |
|
NCBI chr X:104,909,328...104,932,508
Ensembl chr X:104,909,326...104,932,508
|
|
G |
Oxt |
oxytocin/neurophysin I prepropeptide |
multiple interactions |
EXP |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of OXT protein] |
CTD |
PMID:11102496 |
|
NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
|
|
G |
P2rx7 |
purinergic receptor P2X 7 |
multiple interactions |
ISO |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein] |
CTD |
PMID:21638035 |
|
NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein] |
CTD |
PMID:22253048 |
|
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
|
|
|
G |
Ambp |
alpha-1-microglobulin/bikunin precursor |
affects binding |
ISO |
1-anilino-8-naphthalenesulfonate binds to AMBP protein |
CTD |
PMID:16461020 |
|
NCBI chr 5:78,975,690...78,986,021
Ensembl chr 5:78,975,678...78,985,990
|
|
G |
Apod |
apolipoprotein D |
affects binding |
ISO |
1-anilino-8-naphthalenesulfonate binds to APOD protein |
CTD |
PMID:16461020 |
|
NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
|
|
G |
C8g |
complement C8 gamma chain |
affects binding |
ISO |
1-anilino-8-naphthalenesulfonate binds to C8G protein |
CTD |
PMID:16461020 |
|
NCBI chr 3:2,724,616...2,727,616
Ensembl chr 3:2,724,616...2,727,616
|
|
G |
Gsta1 |
glutathione S-transferase alpha 1 |
affects binding |
ISO |
1-anilino-8-naphthalenesulfonate binds to GSTA1 protein |
CTD |
PMID:14690442 |
|
NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
|
|
G |
Lcn2 |
lipocalin 2 |
affects binding |
ISO |
1-anilino-8-naphthalenesulfonate binds to LCN2 protein |
CTD |
PMID:16461020 |
|
NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
|
|
G |
Obp2a |
odorant binding protein 2A |
affects binding |
ISO |
1-anilino-8-naphthalenesulfonate binds to OBP2A protein |
CTD |
PMID:16461020 |
|
NCBI chr 3:2,908,684...2,913,362
Ensembl chr 3:2,910,083...2,913,362
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G |
Orm1 |
orosomucoid 1 |
affects binding |
ISO |
1-anilino-8-naphthalenesulfonate binds to ORM1 protein |
CTD |
PMID:16461020 |
|
NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
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G |
Paep |
progestagen associated endometrial protein |
affects binding |
ISO |
1-anilino-8-naphthalenesulfonate binds to PAEP protein |
CTD |
PMID:16461020 |
|
NCBI chr 3:2,935,396...2,938,883
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|
G |
Ptgds |
prostaglandin D2 synthase |
affects binding |
ISO |
1-anilino-8-naphthalenesulfonate binds to PTGDS protein |
CTD |
PMID:16461020 |
|
NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
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G |
Ttr |
transthyretin |
affects binding multiple interactions |
ISO |
1-anilino-8-naphthalenesulfonate binds to TTR protein 3,3'-dichlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; 3,4-dichlorinated biphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; 4-chlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; Thyroxine inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein] |
CTD |
PMID:23584369 |
|
NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
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G |
Vegp2 |
von Ebners gland protein 2 |
affects binding |
ISO |
1-anilino-8-naphthalenesulfonate binds to LCN1 protein |
CTD |
PMID:16461020 |
|
NCBI chr 3:4,217,260...4,221,330
Ensembl chr 3:4,217,260...4,221,330
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G |
Actb |
actin, beta |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
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G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ARHGDIA mRNA |
CTD |
PMID:15477007 |
|
NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
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G |
Atox1 |
antioxidant 1 copper chaperone |
multiple interactions |
ISO |
ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 mRNA]; ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 protein] |
CTD |
PMID:20194531 |
|
NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941
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G |
Atp7a |
ATPase copper transporting alpha |
multiple interactions |
ISO |
[Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein]; bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]] |
CTD |
PMID:11092760 PMID:21242307 |
|
NCBI chr X:77,076,085...77,193,644
Ensembl chr X:77,076,106...77,193,644
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G |
Atp7b |
ATPase copper transporting beta |
multiple interactions |
ISO |
[Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7B protein] |
CTD |
PMID:21242307 |
|
NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
bathocuproine sulfonate results in decreased expression of BCL2 protein |
CTD |
PMID:24614111 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Bcl2a1 |
BCL2-related protein A1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]] |
CTD |
PMID:15477007 |
|
NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
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G |
Casp3 |
caspase 3 |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein] |
CTD |
PMID:10941151 PMID:11239917 PMID:18056745 |
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NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]] |
CTD |
PMID:15477007 |
|
NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]] |
CTD |
PMID:11006087 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
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G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]] |
CTD |
PMID:15477007 |
|
NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
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G |
Cd200 |
Cd200 molecule |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr11:60,371,617...60,398,450
Ensembl chr11:60,371,684...60,403,196
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G |
Cd44 |
CD44 molecule (Indian blood group) |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
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G |
Cdh17 |
cadherin 17 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CDH17 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 5:25,354,187...25,443,675
Ensembl chr 5:25,391,115...25,443,718
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G |
Clu |
clusterin |
multiple interactions |
ISO |
[Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein]; [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7B protein] |
CTD |
PMID:21242307 |
|
NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
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G |
Cntnap1 |
contactin associated protein 1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CNTNAP1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr10:89,087,904...89,103,615
Ensembl chr10:89,089,646...89,103,614
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G |
Comt |
catechol-O-methyltransferase |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
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G |
Cp |
ceruloplasmin |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein] |
CTD |
PMID:17032174 |
|
NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
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G |
Cpsf1 |
cleavage and polyadenylation specific factor 1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CPSF1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 7:117,661,779...117,672,373
Ensembl chr 7:117,661,661...117,672,373
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CREB1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
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G |
Crem |
cAMP responsive element modulator |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
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G |
Cul5 |
cullin 5 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 8:58,199,992...58,255,149
Ensembl chr 8:58,202,821...58,253,688
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which affects the localization of CYCS protein] |
CTD |
PMID:18056745 |
|
NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of DNAJB1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
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G |
Dusp4 |
dual specificity phosphatase 4 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]] |
CTD |
PMID:15477007 |
|
NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
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G |
Egr2 |
early growth response 2 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
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G |
Egr3 |
early growth response 3 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of EGR3 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [copper histidine results in increased expression of FASN mRNA] |
CTD |
PMID:24170205 |
|
NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]; bathocuproine sulfonate inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:22842628 |
|
NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]] |
CTD |
PMID:15477007 PMID:17032174 |
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NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
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G |
Fyb1 |
FYN binding protein 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 2:55,834,904...55,983,805
Ensembl chr 2:55,835,151...55,983,804
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G |
Gfra2 |
GDNF family receptor alpha 2 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr15:52,557,004...52,648,984
Ensembl chr15:52,557,607...52,648,972
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G |
Gnas |
GNAS complex locus |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GNAS mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483 Ensembl chr 3:172,374,957...172,428,483
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G |
Gtf2h2 |
general transcription factor IIH subunit 2 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GTF2H2C mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 2:30,494,718...30,522,716
Ensembl chr 2:30,494,825...30,522,727
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
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G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[Penicillamine co-treated with bathocuproine sulfonate] results in increased expression of HMOX1 protein |
CTD |
PMID:21242307 |
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NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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G |
Hnrnpul1 |
heterogeneous nuclear ribonucleoprotein U-like 1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HNRNPUL1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 1:82,512,745...82,548,446
Ensembl chr 1:82,512,745...82,546,937
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G |
Hpx |
hemopexin |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [[cobaltiprotoporphyrin co-treated with HPX protein] affects the localization of MTF1 protein]; bathocuproine sulfonate inhibits the reaction [[cobaltiprotoporphyrin co-treated with HPX protein] results in increased expression of MTF1 mRNA]; bathocuproine sulfonate inhibits the reaction [[Heme co-treated with HPX protein] affects the localization of MTF1 protein] |
CTD |
PMID:11213479 |
|
NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HSPA8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]] |
CTD |
PMID:15477007 |
|
NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
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G |
Hyal3 |
hyaluronidase 3 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HYAL3 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 8:116,336,512...116,342,147
Ensembl chr 8:116,336,512...116,342,146
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G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]] |
CTD |
PMID:15477007 |
|
NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
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G |
Il2ra |
interleukin 2 receptor subunit alpha |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]] |
CTD |
PMID:23134680 |
|
NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
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G |
Il2rb |
interleukin 2 receptor subunit beta |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]] |
CTD |
PMID:15477007 PMID:17032174 |
|
NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
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G |
Lcp1 |
lymphocyte cytosolic protein 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr15:57,170,566...57,277,811
Ensembl chr15:57,221,292...57,277,811
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [copper histidine results in increased expression of LDLR mRNA] |
CTD |
PMID:24170205 |
|
NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
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G |
Ltbp4 |
latent transforming growth factor beta binding protein 4 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:84,118,046...84,152,095
Ensembl chr 1:84,118,046...84,150,084
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]] bathocuproine sulfonate inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein] bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein] |
CTD |
PMID:10658192 PMID:15477007 PMID:22842628 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]] bathocuproine sulfonate inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein] bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK3 protein] |
CTD |
PMID:10941151 PMID:15477007 PMID:22842628 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein]; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein] |
CTD |
PMID:10941151 PMID:11239917 PMID:18056745 |
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NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
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G |
Mta1 |
metastasis associated 1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MTA1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 6:137,911,302...137,950,066
Ensembl chr 6:137,924,293...137,950,075
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G |
Mtf1 |
metal-regulatory transcription factor 1 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [[cobaltiprotoporphyrin co-treated with HPX protein] affects the localization of MTF1 protein]; bathocuproine sulfonate inhibits the reaction [[cobaltiprotoporphyrin co-treated with HPX protein] results in increased expression of MTF1 mRNA]; bathocuproine sulfonate inhibits the reaction [[Heme co-treated with HPX protein] affects the localization of MTF1 protein] |
CTD |
PMID:11213479 |
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NCBI chr 5:142,797,340...142,843,896
Ensembl chr 5:142,797,366...142,842,122
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
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G |
Naa80 |
N(alpha)-acetyltransferase 80, NatH catalytic subunit |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:116,336,441...116,339,691
Ensembl chr 8:116,336,441...116,339,690
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G |
Nell1 |
neural EGFL like 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:105,348,577...106,218,970
Ensembl chr 1:105,349,069...106,218,958
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G |
Nfe2l2 |
nuclear factor, erythroid 2-like 2 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of NFE2L2 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]] |
CTD |
PMID:11006087 |
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NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]] |
CTD |
PMID:11006087 |
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NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
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G |
Nmi |
N-myc (and STAT) interactor |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 3:37,458,891...37,480,984
Ensembl chr 3:37,458,890...37,480,984
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G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
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G |
Odc1 |
ornithine decarboxylase 1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ODC1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
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G |
Pax8 |
paired box 8 |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA] |
CTD |
PMID:11108245 |
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NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
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G |
Pcna |
proliferating cell nuclear antigen |
decreases expression |
ISO |
bathocuproine sulfonate results in decreased expression of PCNA protein |
CTD |
PMID:24614111 |
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NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
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G |
Ppp1r10 |
protein phosphatase 1, regulatory subunit 10 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of PPP1R10 mRNA |
CTD |
PMID:15477007 |
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NCBI chr20:3,329,677...3,344,286
Ensembl chr20:3,329,677...3,344,286
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G |
Prnp |
prion protein |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [cupric chloride results in increased expression of PRNP protein] |
CTD |
PMID:16148034 |
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NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
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G |
Rel |
REL proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA] |
CTD |
PMID:15477007 |
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NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
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G |
Sco1 |
synthesis of cytochrome C oxidase 1 |
increases oxidation |
ISO |
bathocuproine sulfonate results in increased oxidation of SCO1 protein |
CTD |
PMID:23345593 |
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NCBI chr10:53,595,854...53,608,437
Ensembl chr10:53,595,854...53,608,435
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G |
Sla |
src-like adaptor |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:107,585,055...107,604,950
Ensembl chr 7:107,584,118...107,634,335
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G |
Slc31a1 |
solute carrier family 31 member 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate results in decreased abundance of Copper] which results in increased expression of SLC31A1 mRNA; bathocuproine sulfonate promotes the reaction [SP1 protein results in increased expression of SLC31A1 mRNA] |
CTD |
PMID:18483225 |
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NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
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G |
Slc31a2 |
solute carrier family 31 member 2 |
multiple interactions affects localization |
ISO |
[[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 protein] which results in increased uptake of and results in increased susceptibility to Cisplatin; [bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 protein ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 mRNA]; ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 protein] bathocuproine sulfonate affects the localization of SLC31A2 protein |
CTD |
PMID:20194531 |
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NCBI chr 5:78,120,606...78,131,111
Ensembl chr 5:78,120,607...78,131,114
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G |
Snrnp70 |
small nuclear ribonucleoprotein U1 subunit 70 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SNRNP70 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 1:101,367,470...101,388,153
Ensembl chr 1:101,367,471...101,388,129
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SOD1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
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G |
Sp1 |
Sp1 transcription factor |
multiple interactions |
ISO |
bathocuproine sulfonate promotes the reaction [SP1 protein results in increased expression of SLC31A1 mRNA] |
CTD |
PMID:18483225 |
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NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
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