CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: lanthanum atom
Accession: CHEBI:33336
browse the term
Definition: A scandium group element atom that has formula La.
Synonyms: related_synonym: 57La; Formula=La; InChI=1S/La; InChIKey=FZLIPJUXYLNCLC-UHFFFAOYSA-N; La; Lanthan; SMILES=[La]; lantano; lanthane; lanthanum
xref: CAS:7439-91-0; Gmelin:16203
xref_mesh: MESH:D007811
xref: WebElements:La
G
Cacna1g
calcium voltage-gated channel subunit alpha1 G
multiple interactions
ISO
Lanthanum inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
G
Camk4
calcium/calmodulin-dependent protein kinase IV
decreases phosphorylation
EXP
Lanthanum results in decreased phosphorylation of CAMK4 protein
CTD
PMID:21695898
NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
G
Casr
calcium-sensing receptor
multiple interactions
ISO
Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Spermine binds to and results in increased activity of CASR protein]
CTD
PMID:17041782 PMID:21562303
NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
G
Chrm1
cholinergic receptor, muscarinic 1
multiple interactions
ISO
Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
CTD
PMID:18316702
NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
G
Creb1
cAMP responsive element binding protein 1
decreases phosphorylation
EXP
Lanthanum results in decreased phosphorylation of CREB1 protein
CTD
PMID:21695898
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
G
Drd1
dopamine receptor D1
multiple interactions
EXP
Lanthanum inhibits the reaction [SCH 23390 binds to DRD1 protein]
CTD
PMID:9109525
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
G
Drd2
dopamine receptor D2
multiple interactions
EXP
Lanthanum inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]
CTD
PMID:9109525
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
G
Egr1
early growth response 1
decreases expression
EXP
Lanthanum results in decreased expression of EGR1 mRNA
CTD
PMID:21695898
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
decreases expression
EXP
Lanthanum results in decreased expression of FOS mRNA
CTD
PMID:21695898
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
G
Gabrb3
gamma-aminobutyric acid type A receptor subunit beta 3
multiple interactions
ISO
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
ISO
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
ISO
Lanthanum binds to and results in increased expression of HSPA5 protein
CTD
PMID:18773883
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
G
Igf2
insulin-like growth factor 2
multiple interactions
ISO
Lanthanum inhibits the reaction [IGF2 protein results in increased import of Calcium]
CTD
PMID:2442157
NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
G
Ins2
insulin 2
decreases response to substance
ISO
Lanthanum results in decreased susceptibility to INS protein
CTD
PMID:22031853
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
decreases expression
EXP
Lanthanum results in decreased expression of JUN mRNA
CTD
PMID:21695898
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Lep
leptin
multiple interactions
ISO
Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]
CTD
PMID:20107083
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Trpc6
transient receptor potential cation channel, subfamily C, member 6
decreases activity
ISO
Lanthanum results in decreased activity of TRPC6 protein
CTD
PMID:11179201
NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
G
Trpm6
transient receptor potential cation channel, subfamily M, member 6
multiple interactions
ISO
Lanthanum inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]
CTD
PMID:11988098
NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
G
Trpv6
transient receptor potential cation channel, subfamily V, member 6
multiple interactions increases uptake
ISO
Lanthanum inhibits the reaction [TRPV6 protein results in increased uptake of Calcium] TRPV6 protein results in increased uptake of Lanthanum
CTD
PMID:21146870
NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017
G
Xbp1
X-box binding protein 1
increases expression
ISO
Lanthanum results in increased expression of XBP1 mRNA alternative form
CTD
PMID:18773883
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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