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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:rubidium atom
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Accession:CHEBI:33322 term browser browse the term
Definition:An alkali metal atom that has formula Rb.
Synonyms:related_synonym: 37Rb;   Formula=Rb;   InChI=1S/Rb;   InChIKey=IGLNJRXAVVLDKE-UHFFFAOYSA-N;   Rb;   SMILES=[Rb];   rubidio;   rubidium
 xref: CAS:7440-17-7;   DrugBank:DB06749;   Gmelin:16244
 xref_mesh: MESH:D012413
 xref: WebElements:Rb



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rubidium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 multiple interactions EXP
ISO
[KCNJ11 protein binds to ABCC8 protein] which results in increased export of Rubidium
[KCNJ8 protein binds to ABCC8 protein] which results in increased export of Rubidium
CTD PMID:28842488 NCBI chr 7:45,753,947...45,829,457
Ensembl chr 7:45,753,947...45,829,457
JBrowse link
G Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 multiple interactions EXP
ISO
[KCNJ11 protein binds to ABCC9 protein] which results in increased export of Rubidium
[KCNJ8 protein binds to ABCC9 protein] which results in increased export of Rubidium
CTD PMID:28842488 NCBI chr 6:142,533,588...142,648,472
Ensembl chr 6:142,533,588...142,648,041
JBrowse link
G Atp12a ATPase, H+/K+ transporting, nongastric, alpha polypeptide multiple interactions ISO [ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium; Ouabain inhibits the reaction [[ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium]; Sch 28080 inhibits the reaction [[ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium] CTD PMID:8853415 NCBI chr14:56,602,525...56,626,008
Ensembl chr14:56,602,525...56,626,007
JBrowse link
G Atp4b ATPase, H+/K+ exchanging, beta polypeptide multiple interactions ISO [ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium; Ouabain inhibits the reaction [[ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium]; Sch 28080 inhibits the reaction [[ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium] CTD PMID:8853415 NCBI chr 8:13,436,209...13,446,778
Ensembl chr 8:13,436,205...13,446,825
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 multiple interactions ISO Rubidium inhibits the reaction [Gramicidin results in decreased expression of KCNH2 protein modified form] CTD PMID:19139152 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 multiple interactions EXP [KCNJ11 protein binds to ABCC8 protein] which results in increased export of Rubidium; [KCNJ11 protein binds to ABCC9 protein] which results in increased export of Rubidium CTD PMID:28842488 NCBI chr 7:45,746,547...45,750,376
Ensembl chr 7:45,743,377...45,750,188
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 multiple interactions ISO [KCNJ8 protein binds to ABCC8 protein] which results in increased export of Rubidium; [KCNJ8 protein binds to ABCC9 protein] which results in increased export of Rubidium CTD PMID:28842488 NCBI chr 6:142,510,563...142,517,340
Ensembl chr 6:142,510,563...142,517,340
JBrowse link
G Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 affects activity EXP Rubidium affects the activity of KCNMA1 protein CTD PMID:16636204 NCBI chr14:23,342,356...24,055,173
Ensembl chr14:23,339,499...24,064,559
JBrowse link
G Kcnq4 potassium voltage-gated channel, subfamily Q, member 4 multiple interactions ISO [ezogabine results in increased activity of KCNQ4 protein] which results in increased export of Rubidium CTD PMID:21782781 NCBI chr 4:120,553,331...120,604,687
Ensembl chr 4:120,553,335...120,605,809
JBrowse link
G Slc12a2 solute carrier family 12, member 2 multiple interactions
increases uptake
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine promotes the reaction [SLC12A2 protein results in increased uptake of Rubidium]]; [calyculin A results in increased phosphorylation of SLC12A2 protein] inhibits the reaction [Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]]; Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Phenylephrine promotes the reaction [SLC12A2 protein results in increased uptake of Rubidium]
azosemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Ethacrynic Acid inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Furosemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; piretanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Ticrynafen inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Torsemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]
CTD PMID:14630635 PMID:29959396 NCBI chr18:58,011,505...58,079,893
Ensembl chr18:58,011,750...58,079,893
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 increases transport EXP TRPC6 protein results in increased transport of Rubidium CTD PMID:11179201 NCBI chr 9:8,543,868...8,680,753
Ensembl chr 9:8,544,143...8,680,742
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21845
    chemical entity 21843
      atom 21831
        metal atom 18430
          alkali metal atom 12424
            rubidium atom 11
              rubidium molecular entity + 0
              rubidium-85 atom 0
              rubidium-87 atom 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21845
    subatomic particle 21831
      composite particle 21831
        hadron 21831
          baryon 21831
            nucleon 21831
              atomic nucleus 21831
                atom 21831
                  metal atom 18430
                    alkali metal atom 12424
                      rubidium atom 11
                        rubidium molecular entity + 0
                        rubidium-85 atom 0
                        rubidium-87 atom 0
paths to the root