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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:rubidium atom
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Accession:CHEBI:33322 term browser browse the term
Definition:An alkali metal atom that has formula Rb.
Synonyms:related_synonym: 37Rb;   Formula=Rb;   InChI=1S/Rb;   InChIKey=IGLNJRXAVVLDKE-UHFFFAOYSA-N;   Rb;   SMILES=[Rb];   rubidio;   rubidium
 xref: CAS:7440-17-7;   DrugBank:DB06749;   Gmelin:16244
 xref_mesh: MESH:D012413
 xref: WebElements:Rb


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rubidium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 multiple interactions ISO [KCNJ11 protein binds to ABCC8 protein] which results in increased export of Rubidium
[KCNJ8 protein binds to ABCC8 protein] which results in increased export of Rubidium		 CTD PMID:28842488 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 multiple interactions ISO [KCNJ11 protein binds to ABCC9 protein] which results in increased export of Rubidium
[KCNJ8 protein binds to ABCC9 protein] which results in increased export of Rubidium		 CTD PMID:28842488 NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543 		JBrowse link
G ATP12A ATPase H+/K+ transporting non-gastric alpha2 subunit multiple interactions EXP [ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium; Ouabain inhibits the reaction [[ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium]; Sch 28080 inhibits the reaction [[ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium] CTD PMID:8853415 NCBI chr13:24,680,408...24,712,472
Ensembl chr13:24,680,408...24,712,472 		JBrowse link
G ATP4B ATPase H+/K+ transporting subunit beta multiple interactions EXP [ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium; Ouabain inhibits the reaction [[ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium]; Sch 28080 inhibits the reaction [[ATP12A protein co-treated with ATP4B protein] results in increased uptake of Rubidium] CTD PMID:8853415 NCBI chr13:113,648,804...113,658,198
Ensembl chr13:113,648,804...113,658,198 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 multiple interactions EXP Rubidium inhibits the reaction [Gramicidin results in decreased expression of KCNH2 protein modified form] CTD PMID:19139152 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 multiple interactions ISO [KCNJ11 protein binds to ABCC8 protein] which results in increased export of Rubidium; [KCNJ11 protein binds to ABCC9 protein] which results in increased export of Rubidium CTD PMID:28842488 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 multiple interactions ISO [KCNJ8 protein binds to ABCC8 protein] which results in increased export of Rubidium; [KCNJ8 protein binds to ABCC9 protein] which results in increased export of Rubidium CTD PMID:28842488 NCBI chr12:21,764,955...21,774,706
Ensembl chr12:21,764,955...21,775,600 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 affects activity ISO Rubidium affects the activity of KCNMA1 protein CTD PMID:16636204 NCBI chr10:76,869,602...77,637,808
Ensembl chr10:76,869,601...77,638,369 		JBrowse link
G KCNQ4 potassium voltage-gated channel subfamily Q member 4 multiple interactions EXP [ezogabine results in increased activity of KCNQ4 protein] which results in increased export of Rubidium CTD PMID:21782781 NCBI chr 1:40,783,787...40,840,452
Ensembl chr 1:40,783,787...40,840,452 		JBrowse link
G SLC12A2 solute carrier family 12 member 2 multiple interactions
increases uptake		 ISO
EXP		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine promotes the reaction [SLC12A2 protein results in increased uptake of Rubidium]]; [calyculin A results in increased phosphorylation of SLC12A2 protein] inhibits the reaction [Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]]; Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Phenylephrine promotes the reaction [SLC12A2 protein results in increased uptake of Rubidium]
azosemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Ethacrynic Acid inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Furosemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; piretanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Ticrynafen inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Torsemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]		 CTD PMID:14630635 PMID:29959396 NCBI chr 5:128,083,766...128,189,677
Ensembl chr 5:128,083,766...128,189,677 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 increases transport ISO TRPC6 protein results in increased transport of Rubidium CTD PMID:11179201 NCBI chr11:101,451,564...101,584,007
Ensembl chr11:101,451,564...101,872,562 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 25336
    chemical entity 25310
      atom 25302
        metal atom 19939
          alkali metal atom 13464
            rubidium atom 11
              rubidium molecular entity + 0
              rubidium-85 atom 0
              rubidium-87 atom 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 25336
    subatomic particle 25302
      composite particle 25302
        hadron 25302
          baryon 25302
            nucleon 25302
              atomic nucleus 25302
                atom 25302
                  metal atom 19939
                    alkali metal atom 13464
                      rubidium atom 11
                        rubidium molecular entity + 0
                        rubidium-85 atom 0
                        rubidium-87 atom 0
paths to the root