Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:diagnostic agent
go back to main search page
Accession:CHEBI:33295 term browser browse the term
Definition:A substance administered to aid diagnosis of a disease.
Synonyms:related_synonym: diagnostic aid


show annotations for term's descendants           Sort by:
 
2',7'-bis-(2-carboxyethyl)carboxyfluorescein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 multiple interactions ISO Mefloquine inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; verlukast inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein] CTD PMID:16004972 NCBI chr14:118,482,692...118,707,856
Ensembl chr14:118,482,692...118,706,219
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 increases export
multiple interactions
ISO ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein
daidzein inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; hesperetin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; naringenin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Quercetin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; resveratrol inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Silymarin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; verlukast inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]
CTD PMID:16156793 NCBI chr16:20,331,303...20,426,428
Ensembl chr16:20,331,303...20,426,394
JBrowse link
5(6)-carboxy-2',7'-dichlorofluorescein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 affects transport
multiple interactions
increases export
increases transport
ISO ABCC2 protein affects the transport of 5(6)-carboxy-2',7'-dichlorofluorescein
4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein; Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]; Ascorbic Acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; cyanoginosin LR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Cyclosporine inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; microcystin RR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; microcystin-LF inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Probenecid inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Tobacco Smoke Pollution inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]
ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein; ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog
[ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein; ABCC2 gene mutant form inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Rosuvastatin Calcium promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD PMID:19326901 PMID:21240898 PMID:21341280 PMID:23562342 PMID:24907646 More... NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 multiple interactions
increases transport
ISO [ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein
Benzbromarone inhibits the reaction [ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD PMID:24907646 PMID:31348918 NCBI chr11:94,343,295...94,393,017
Ensembl chr11:94,343,295...94,392,997
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 multiple interactions
increases transport
ISO Benzbromarone inhibits the reaction [ABCC5 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:31348918 NCBI chr16:20,331,303...20,426,428
Ensembl chr16:20,331,303...20,426,394
JBrowse link
5-carboxyfluorescein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 multiple interactions
increases transport
ISO quercetin 3'-sulfate inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide analog inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein] CTD PMID:21244849 NCBI chr19:8,591,254...8,611,835
Ensembl chr19:8,591,254...8,611,835
JBrowse link
5-chloromethylfluorescein diacetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 multiple interactions ISO ABCC2 protein affects the transport of [5-chloromethylfluorescein co-treated with Glutathione] CTD PMID:16049127 NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740
JBrowse link
6-carboxyfluorescein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 increases export ISO ABCC1 protein results in increased export of 6-carboxyfluorescein CTD PMID:17940500 NCBI chr16:14,361,453...14,474,878
Ensembl chr16:14,361,558...14,475,737
JBrowse link
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 affects export
multiple interactions
ISO ABCC2 protein affects the export of 6-carboxyfluorescein
Probenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein]
CTD PMID:11477083 NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740
JBrowse link
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 increases import
multiple interactions
ISO SLC22A6 protein results in increased import of 6-carboxyfluorescein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; glutaric acid promotes the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]
CTD PMID:28629854 NCBI chr19:8,617,996...8,628,299
Ensembl chr19:8,618,039...8,628,299
JBrowse link
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 increases import
multiple interactions
ISO SLC22A8 protein results in increased import of 6-carboxyfluorescein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine promotes the reaction [2-amino-9H-pyrido(2,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]]; 2-amino-9H-pyrido(2,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; 2-amino-9H-pyrido(2,3-b)indole promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]]; 3-amino-1-methyl-5H-pyrido(4,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Cadmium Chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; glutaric acid promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; lead chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; sodium arsenate promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]
CTD PMID:28629854 NCBI chr19:8,591,254...8,611,835
Ensembl chr19:8,591,254...8,611,835
JBrowse link
amidotrizoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) multiple interactions
increases expression
ISO telmisartan inhibits the reaction [Diatrizoate results in increased expression of AGT protein] CTD PMID:19452295 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
decreases phosphorylation
ISO Plant Extracts inhibits the reaction [Diatrizoate results in decreased phosphorylation of AKT1 protein] CTD PMID:25603236 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO [Diatrizoate co-treated with Iodine] results in increased expression of BAX protein CTD PMID:17173243 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO [Diatrizoate co-treated with Iodine] results in increased expression of BCL2 protein CTD PMID:17173243 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Casp3 caspase 3 affects expression
multiple interactions
increases activity
ISO Diatrizoate affects the expression of CASP3 protein
[Diatrizoate co-treated with Iodine] results in increased activity of CASP3 protein
telmisartan inhibits the reaction [Diatrizoate results in increased activity of CASP3 protein]
CTD PMID:17173243 PMID:19452295 PMID:21036957 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases secretion ISO Diatrizoate results in increased secretion of CXCL8 protein CTD PMID:21036957 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G F2 coagulation factor II multiple interactions ISO Diatrizoate inhibits the reaction [F2 protein binds to SERPINC1 protein] CTD PMID:2020943 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414
JBrowse link
G Foxo1 forkhead box O1 decreases phosphorylation
multiple interactions
ISO Diatrizoate results in decreased phosphorylation of FOXO1 protein
Plant Extracts inhibits the reaction [Diatrizoate results in decreased phosphorylation of FOXO1 protein]
CTD PMID:25603236 NCBI chr 3:52,268,337...52,350,109
Ensembl chr 3:52,268,336...52,353,221
JBrowse link
G Foxo3 forkhead box O3 affects phosphorylation ISO Diatrizoate affects the phosphorylation of FOXO3 protein CTD PMID:21036957 NCBI chr10:42,181,845...42,276,695
Ensembl chr10:42,181,841...42,276,755
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 affects phosphorylation
multiple interactions
ISO Diatrizoate affects the phosphorylation of MAPK1 protein
Plant Extracts affects the reaction [Diatrizoate affects the phosphorylation of MAPK1 protein]
CTD PMID:25603236 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
affects phosphorylation
ISO Plant Extracts affects the reaction [Diatrizoate affects the phosphorylation of MAPK3 protein] CTD PMID:25603236 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Diatrizoate results in increased phosphorylation of MAPK8 protein CTD PMID:21036957 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO Diatrizoate results in increased phosphorylation of MAPK9 protein CTD PMID:21036957 NCBI chr11:49,846,728...49,886,421
Ensembl chr11:49,846,751...49,886,421
JBrowse link
G Pim1 proviral integration site 1 decreases expression
multiple interactions
ISO Diatrizoate results in decreased expression of PIM1 protein
Plant Extracts inhibits the reaction [Diatrizoate results in decreased expression of PIM1 protein]
CTD PMID:25603236 NCBI chr17:29,490,785...29,496,111
Ensembl chr17:29,490,753...29,496,112
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) increases phosphorylation ISO Diatrizoate results in increased phosphorylation of RELA protein CTD PMID:21036957 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 multiple interactions ISO Diatrizoate inhibits the reaction [F2 protein binds to SERPINC1 protein] CTD PMID:2020943 NCBI chr 1:160,978,583...161,002,543
Ensembl chr 1:160,978,585...161,005,863
JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects expression ISO Diatrizoate affects the expression of STAT3 protein modified form CTD PMID:21036957 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
barium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin increases expression ISO Barium Sulfate results in increased expression of ALB mRNA CTD PMID:29463257 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Barium Sulfate results in increased expression of BIRC5 mRNA CTD PMID:29463257 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 increases expression ISO Barium Sulfate results in increased expression of CCL11 mRNA CTD PMID:29463257 NCBI chr11:82,057,832...82,062,955
Ensembl chr11:82,057,823...82,062,955
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 increases expression
increases secretion
ISO Barium Sulfate results in increased expression of CCL2 mRNA
Barium Sulfate results in increased secretion of CCL2 protein
CTD PMID:29463257 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 affects expression ISO Barium Sulfate affects the expression of CCL20 mRNA CTD PMID:29463257 NCBI chr 1:83,116,766...83,119,167
Ensembl chr 1:83,116,766...83,119,167
JBrowse link
G Ccl22 chemokine (C-C motif) ligand 22 increases expression ISO Barium Sulfate results in increased expression of CCL22 mRNA CTD PMID:29463257 NCBI chr 8:94,745,684...94,751,388
Ensembl chr 8:94,745,590...94,751,699
JBrowse link
G Ccl24 chemokine (C-C motif) ligand 24 increases expression ISO Barium Sulfate results in increased expression of CCL24 mRNA CTD PMID:29463257 NCBI chr 5:135,569,935...135,573,123
Ensembl chr 5:135,569,937...135,573,049
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 decreases expression ISO Barium Sulfate results in decreased expression of CCL4 mRNA CTD PMID:29463257 NCBI chr11:83,648,624...83,664,683
Ensembl chr11:83,662,584...83,664,683
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 increases expression ISO Barium Sulfate results in increased expression of CCL7 mRNA CTD PMID:29463257 NCBI chr11:82,045,712...82,047,525
Ensembl chr11:82,045,712...82,047,525
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 increases expression ISO Barium Sulfate results in increased expression of CCR2 mRNA CTD PMID:29463257 NCBI chr 9:124,101,918...124,109,140
Ensembl chr 9:124,101,950...124,113,557
JBrowse link
G Cd40lg CD40 ligand decreases expression ISO Barium Sulfate results in decreased expression of CD40LG mRNA CTD PMID:29463257 NCBI chr  X:57,212,143...57,224,042
Ensembl chr  X:57,212,143...57,224,042
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 increases expression ISO Barium Sulfate results in increased expression of CXCL9 mRNA CTD PMID:29463257 NCBI chr 5:92,321,331...92,328,079
Ensembl chr 5:92,321,347...92,328,079
JBrowse link
G Cxcr3 chemokine (C-X-C motif) receptor 3 increases expression ISO Barium Sulfate results in increased expression of CXCR3 mRNA CTD PMID:29463257 NCBI chr  X:101,731,535...101,734,147
Ensembl chr  X:101,731,535...101,734,269
JBrowse link
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B increases expression ISO Barium Sulfate results in increased expression of CYP4A1 mRNA CTD PMID:11124224 NCBI chr 4:115,411,624...115,439,034
Ensembl chr 4:115,411,624...115,439,034
JBrowse link
G Cyp4f14 cytochrome P450, family 4, subfamily f, polypeptide 14 increases expression ISO Barium Sulfate results in increased expression of CYP4F1 mRNA CTD PMID:14644421 NCBI chr17:32,903,357...32,917,376
Ensembl chr17:32,905,070...32,917,342
JBrowse link
G Cyp4f16 cytochrome P450, family 4, subfamily f, polypeptide 16 increases expression ISO Barium Sulfate results in increased expression of CYP4F6 mRNA CTD PMID:14644421 NCBI chr17:32,536,545...32,551,798
Ensembl chr17:32,536,558...32,551,798
JBrowse link
G Exo1 exonuclease 1 affects expression ISO Barium Sulfate affects the expression of EXO1 mRNA CTD PMID:29463257 NCBI chr 1:175,880,768...175,911,396
Ensembl chr 1:175,880,581...175,913,489
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte decreases expression ISO Barium Sulfate results in decreased expression of FABP4 mRNA CTD PMID:29463257 NCBI chr 3:10,204,342...10,208,616
Ensembl chr 3:10,204,088...10,208,576
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression ISO Barium Sulfate results in decreased expression of HBA1 mRNA CTD PMID:29463257 NCBI chr11:32,296,492...32,297,310
Ensembl chr11:32,296,489...32,297,298
JBrowse link
G Il2rb interleukin 2 receptor, beta chain decreases expression ISO Barium Sulfate results in decreased expression of IL2RB mRNA CTD PMID:29463257 NCBI chr15:78,479,256...78,511,621
Ensembl chr15:78,479,256...78,495,271
JBrowse link
G Il6 interleukin 6 increases expression ISO Barium Sulfate results in increased expression of IL6 protein CTD PMID:11403239 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Krt1 keratin 1 increases expression ISO Barium Sulfate results in increased expression of KRT1 mRNA CTD PMID:29463257 NCBI chr15:101,845,426...101,850,786
Ensembl chr15:101,845,426...101,850,794
JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent increases expression ISO Barium Sulfate results in increased expression of LIG4 mRNA CTD PMID:29463257 NCBI chr 8:9,970,020...9,977,680
Ensembl chr 8:9,969,049...9,977,686
JBrowse link
G Lpo lactoperoxidase increases expression ISO Barium Sulfate results in increased expression of LPO mRNA; Barium Sulfate results in increased expression of LPO protein CTD PMID:29463257 NCBI chr11:87,806,428...87,826,114
Ensembl chr11:87,806,428...87,828,289
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Barium Sulfate results in increased expression of MMP12 mRNA; Barium Sulfate results in increased expression of MMP12 protein CTD PMID:29463257 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
JBrowse link
G Mutyh mutY DNA glycosylase increases expression ISO Barium Sulfate results in increased expression of MUTYH mRNA CTD PMID:29463257 NCBI chr 4:116,807,636...116,819,439
Ensembl chr 4:116,807,723...116,819,440
JBrowse link
G Ngb neuroglobin decreases expression ISO Barium Sulfate results in decreased expression of NGB mRNA CTD PMID:29463257 NCBI chr12:87,097,531...87,102,539
Ensembl chr12:87,097,531...87,102,539
JBrowse link
G Noxo1 NADPH oxidase organizer 1 increases expression ISO Barium Sulfate results in increased expression of NOXO1 mRNA CTD PMID:29463257 NCBI chr17:24,696,234...24,700,530
Ensembl chr17:24,696,234...24,700,529
JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like increases expression ISO Barium Sulfate results in increased expression of OPCML mRNA CTD PMID:29463257 NCBI chr 9:27,790,716...28,925,410
Ensembl chr 9:27,790,775...28,925,410
JBrowse link
G Pf4 platelet factor 4 increases expression ISO Barium Sulfate results in increased expression of PF4 mRNA CTD PMID:29463257 NCBI chr 5:90,772,435...90,773,383
Ensembl chr 5:90,772,435...90,773,383
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 affects expression ISO Barium Sulfate affects the expression of SCD1 mRNA CTD PMID:29463257 NCBI chr19:44,394,450...44,407,709
Ensembl chr19:44,394,455...44,407,879
JBrowse link
G Tcf21 transcription factor 21 decreases expression ISO Barium Sulfate results in decreased expression of TCF21 mRNA CTD PMID:29463257 NCBI chr10:22,817,263...22,820,143
Ensembl chr10:22,817,281...22,820,174
JBrowse link
G Thbs2 thrombospondin 2 increases expression ISO Barium Sulfate results in increased expression of THBS2 mRNA CTD PMID:29463257 NCBI chr17:14,665,500...14,694,262
Ensembl chr17:14,665,500...14,694,235
JBrowse link
G Top2a topoisomerase (DNA) II alpha increases expression ISO Barium Sulfate results in increased expression of TOP2A mRNA CTD PMID:29463257 NCBI chr11:98,992,947...99,024,199
Ensembl chr11:98,992,943...99,024,189
JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO Barium Sulfate results in decreased expression of TXNIP mRNA CTD PMID:29463257 NCBI chr 3:96,557,957...96,561,857
Ensembl chr 3:96,557,957...96,561,883
JBrowse link
G Xrcc2 X-ray repair complementing defective repair in Chinese hamster cells 2 increases expression ISO Barium Sulfate results in increased expression of XRCC2 mRNA CTD PMID:29463257 NCBI chr 5:25,689,814...25,705,797
Ensembl chr 5:25,689,812...25,705,825
JBrowse link
ceruletide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions
increases expression
EXP PTHLH protein promotes the reaction [Ceruletide results in increased expression of ACTA2 protein] CTD PMID:25035110 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Ahcy S-adenosylhomocysteine hydrolase decreases expression ISO Ceruletide results in decreased expression of AHCY protein CTD PMID:18024178 NCBI chr 2:155,059,310...155,074,497
Ensembl chr 2:155,059,310...155,074,497
JBrowse link
G Akr1b3 aldo-keto reductase family 1, member B3 (aldose reductase) increases expression ISO Ceruletide results in increased expression of AKR1B1 protein CTD PMID:18024178 NCBI chr 6:34,303,930...34,317,489
Ensembl chr 6:34,302,434...34,317,478
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions EXP (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of AKT1 protein]; [KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of AKT1 protein CTD PMID:26390243 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Alb albumin decreases expression ISO Ceruletide results in decreased expression of ALB protein modified form CTD PMID:17169977 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 increases expression EXP Ceruletide results in increased expression of BDKRB1 mRNA CTD PMID:21484880 NCBI chr12:105,604,091...105,605,511
Ensembl chr12:105,603,085...105,605,428
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 increases expression EXP Ceruletide results in increased expression of BDKRB2 mRNA CTD PMID:21484880 NCBI chr12:105,563,172...105,595,244
Ensembl chr12:105,563,226...105,595,237
JBrowse link
G Brd4 bromodomain containing 4 multiple interactions EXP (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased expression of BRD4 protein]; [KRAS protein mutant form co-treated with Ceruletide] results in increased expression of BRD4 protein CTD PMID:26390243 NCBI chr17:32,196,272...32,284,743
Ensembl chr17:32,196,274...32,284,722
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Glycodeoxycholic Acid co-treated with Ceruletide] results in decreased activity of CASP3 protein; Ceruletide results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:16339139 PMID:18832452 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Ceruletide results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:16339139 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Ceruletide results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:16339139 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions
increases expression
EXP PPARG affects the reaction [Ceruletide results in increased expression of CCL2 mRNA]; rosiglitazone inhibits the reaction [Ceruletide results in increased expression of CCL2 mRNA] CTD PMID:17463185 PMID:21484880 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Cct2 chaperonin containing Tcp1, subunit 2 (beta) increases expression ISO Ceruletide results in increased expression of CCT2 protein CTD PMID:18024178 NCBI chr10:117,050,997...117,063,852
Ensembl chr10:117,051,001...117,063,814
JBrowse link
G Cebpa CCAAT/enhancer binding protein (C/EBP), alpha increases expression
multiple interactions
ISO Ceruletide results in increased expression of CEBPA mRNA
[Dietary Fats co-treated with Ceruletide] results in increased expression of CEBPA protein; Dietary Fats promotes the reaction [Ceruletide results in increased expression of CEBPA mRNA]; Quercetin inhibits the reaction [[Dietary Fats co-treated with Ceruletide] results in increased expression of CEBPA protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of CEBPA mRNA]
CTD PMID:26873426 NCBI chr 7:35,119,293...35,121,928
Ensembl chr 7:35,119,293...35,121,928
JBrowse link
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta multiple interactions
increases expression
ISO [Dietary Fats co-treated with Ceruletide] results in increased expression of CEBPB protein; Dietary Fats promotes the reaction [Ceruletide results in increased expression of CEBPB mRNA]; Quercetin inhibits the reaction [[Dietary Fats co-treated with Ceruletide] results in increased expression of CEBPB protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of CEBPB mRNA] CTD PMID:26873426 NCBI chr 2:167,688,915...167,690,432
Ensembl chr 2:167,688,915...167,690,418
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions
increases expression
ISO
EXP
PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of COL1A1 mRNA]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of COL1A1 mRNA]
PTHLH protein inhibits the reaction [Ceruletide results in increased expression of COL1A1 mRNA]
CTD PMID:22280800 PMID:25035110 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Ctsb cathepsin B affects localization
multiple interactions
ISO Ceruletide affects the localization of CTSB protein
sodium arsenite inhibits the reaction [Ceruletide affects the localization of CTSB protein]
CTD PMID:17941083 NCBI chr14:63,122,462...63,145,923
Ensembl chr14:63,122,462...63,145,923
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 increases expression
multiple interactions
EXP Ceruletide results in increased expression of CXCL1 mRNA
AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]; AM 251 promotes the reaction [iodopravadoline inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]]; HU 211 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]; iodopravadoline inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]; iodopravadoline promotes the reaction [AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]]; PPARG affects the reaction [Ceruletide results in increased expression of CXCL1 mRNA]
CTD PMID:17463185 PMID:17484889 NCBI chr 5:90,786,101...90,788,093
Ensembl chr 5:90,786,103...90,789,600
JBrowse link
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 increases expression
multiple interactions
ISO Ceruletide results in increased expression of ERN1 mRNA; Ceruletide results in increased expression of ERN1 protein
Dietary Fats promotes the reaction [Ceruletide results in increased expression of ERN1 mRNA]; Dietary Fats promotes the reaction [Ceruletide results in increased expression of ERN1 protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of ERN1 mRNA]; Quercetin inhibits the reaction [Ceruletide results in increased expression of ERN1 protein]
CTD PMID:26873426 NCBI chr11:106,397,620...106,487,796
Ensembl chr11:106,394,650...106,487,852
JBrowse link
G Glud1 glutamate dehydrogenase 1 increases expression ISO Ceruletide results in increased expression of GLUD1 protein CTD PMID:18024178 NCBI chr14:34,310,727...34,345,033
Ensembl chr14:34,310,727...34,345,265
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble increases expression
multiple interactions
EXP Ceruletide results in increased expression of GPT protein
isoborneol inhibits the reaction [Ceruletide results in increased expression of GPT protein]
CTD PMID:33166053 NCBI chr15:76,696,726...76,699,675
Ensembl chr15:76,695,716...76,699,686
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 increases expression ISO Ceruletide results in increased expression of HNRNPH1 protein CTD PMID:18024178 NCBI chr11:50,375,257...50,386,528
Ensembl chr11:50,376,990...50,386,528
JBrowse link
G Hspa5 heat shock protein 5 decreases expression ISO Ceruletide results in decreased expression of HSPA5 protein CTD PMID:18024178 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Hspa8 heat shock protein 8 decreases expression ISO Ceruletide results in decreased expression of HSPA8 protein CTD PMID:18024178 NCBI chr 9:40,801,276...40,805,202
Ensembl chr 9:40,800,984...40,810,087
JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression ISO Ceruletide results in increased expression of HYOU1 protein CTD PMID:18024178 NCBI chr 9:44,379,490...44,392,369
Ensembl chr 9:44,379,490...44,392,369
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO
EXP
PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of ICAM1 mRNA]
rosiglitazone inhibits the reaction [Ceruletide results in increased expression of ICAM1 mRNA]
CTD PMID:17463185 PMID:25035110 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [resveratrol co-treated with Ceruletide] results in increased expression of IL10 protein CTD PMID:24234420 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
increases secretion
ISO
EXP
Ceruletide results in increased expression of IL1B mRNA; Ceruletide results in increased expression of IL1B protein
isoborneol inhibits the reaction [Ceruletide results in increased expression of IL1B protein]
Dietary Fats promotes the reaction [Ceruletide results in increased expression of IL1B mRNA]; Dietary Fats promotes the reaction [Ceruletide results in increased secretion of IL1B protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [Dietary Fats promotes the reaction [Ceruletide results in increased expression of IL1B mRNA]]; resveratrol inhibits the reaction [Ceruletide results in increased expression of IL1B protein]
CTD PMID:14751415 PMID:21484880 PMID:24234420 PMID:26873426 PMID:33166053 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
increases secretion
ISO
EXP
Ceruletide results in increased expression of IL6 mRNA
Dietary Fats promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]; Dietary Fats promotes the reaction [Ceruletide results in increased secretion of IL6 protein]; PTHLH protein inhibits the reaction [Ceruletide results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [Ceruletide results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [Dietary Fats promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]]
(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased expression of IL6 protein]; [KRAS protein mutant form co-treated with Ceruletide] results in increased expression of IL6 protein; HU 211 inhibits the reaction [Ceruletide results in increased expression of IL6 protein]; IL6 protein inhibits the reaction [(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]]; isoborneol inhibits the reaction [Ceruletide results in increased expression of IL6 protein]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]
Ceruletide results in increased expression of IL6 mRNA; Ceruletide results in increased expression of IL6 protein
PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of IL6 mRNA]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]
CTD PMID:17484889 PMID:22280800 PMID:25035110 PMID:26390243 PMID:26873426 More... NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Jun jun proto-oncogene increases expression
multiple interactions
EXP Ceruletide results in increased expression of JUN mRNA
rosiglitazone inhibits the reaction [Ceruletide results in increased expression of JUN mRNA]
CTD PMID:17463185 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog multiple interactions EXP (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased expression of BRD4 protein]; (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased expression of IL6 protein]; (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of AKT1 protein]; (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]; [KRAS protein mutant form co-treated with Ceruletide] results in increased expression of BRD4 protein; [KRAS protein mutant form co-treated with Ceruletide] results in increased expression of IL6 protein; [KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of AKT1 protein; [KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein; IL6 protein inhibits the reaction [(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]] CTD PMID:26390243 NCBI chr 6:145,216,699...145,250,420
Ensembl chr 6:145,216,699...145,250,239
JBrowse link
G Mir216a microRNA 216a increases expression ISO Ceruletide results in increased expression of MIR216A mRNA CTD PMID:27521901 NCBI chr11:28,757,012...28,757,083
Ensembl chr11:28,757,012...28,757,083
JBrowse link
G Mir216b microRNA 216b increases expression ISO Ceruletide results in increased expression of MIR216B mRNA CTD PMID:27521901 NCBI chr11:28,746,191...28,746,276
Ensembl chr11:28,746,191...28,746,276
JBrowse link
G Mir217 microRNA 217 increases expression ISO Ceruletide results in increased expression of MIR217 mRNA CTD PMID:27521901 NCBI chr11:28,763,728...28,763,835
Ensembl chr11:28,763,728...28,763,835
JBrowse link
G Mpo myeloperoxidase increases expression
increases activity
multiple interactions
EXP Ceruletide results in increased expression of MPO protein
Ceruletide results in increased activity of MPO protein
HU 211 inhibits the reaction [Ceruletide results in increased expression of MPO protein]; isoborneol inhibits the reaction [Ceruletide results in increased activity of MPO protein]
CTD PMID:17484889 PMID:33166053 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases expression
multiple interactions
EXP Ceruletide results in decreased expression of NFE2L2 protein
isoborneol inhibits the reaction [Ceruletide results in decreased expression of NFE2L2 protein]
CTD PMID:33166053 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha increases degradation
multiple interactions
ISO Ceruletide results in increased degradation of NFKBIA protein
sodium arsenite inhibits the reaction [Ceruletide results in increased degradation of NFKBIA protein]
CTD PMID:17941083 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases expression
EXP isoborneol inhibits the reaction [Ceruletide results in increased expression of NOS2 protein] CTD PMID:33166053 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Pdia4 protein disulfide isomerase associated 4 increases expression ISO Ceruletide results in increased expression of PDIA4 protein CTD PMID:18024178 NCBI chr 6:47,796,141...47,813,512
Ensembl chr 6:47,796,141...47,813,430
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions EXP PPARG affects the reaction [Ceruletide results in increased expression of CCL2 mRNA]; PPARG affects the reaction [Ceruletide results in increased expression of CXCL1 mRNA] CTD PMID:17463185 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Prdx2 peroxiredoxin 2 increases expression ISO Ceruletide results in increased expression of PRDX2 protein CTD PMID:18024178 NCBI chr 8:84,969,622...84,974,811
Ensembl chr 8:84,969,587...84,974,834
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Ceruletide results in increased expression of PTGS2 mRNA; Ceruletide results in increased expression of PTGS2 protein CTD PMID:14751415 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Pthlh parathyroid hormone-like peptide multiple interactions
affects response to substance
increases expression
ISO
EXP
PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of COL1A1 mRNA]; PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of ICAM1 mRNA]; PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of IL6 mRNA]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of COL1A1 mRNA]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]
Ethanol results in increased susceptibility to [Ceruletide results in increased expression of PTHLH mRNA]; PTHLH protein inhibits the reaction [Ceruletide results in increased expression of COL1A1 mRNA]; PTHLH protein inhibits the reaction [Ceruletide results in increased expression of IL6 mRNA]
PTHLH protein affects the susceptibility to Ceruletide
Ceruletide results in increased expression of PTHLH mRNA; Ceruletide results in increased expression of PTHLH protein
PTHLH protein promotes the reaction [Ceruletide results in increased expression of ACTA2 protein]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of COL1A1 mRNA]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]
CTD PMID:22280800 PMID:25035110 NCBI chr 6:147,252,109...147,264,013
Ensembl chr 6:147,252,101...147,264,183
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
decreases phosphorylation
increases expression
EXP ent-1,3,6,11-tetrahydroxykaur-16-ene-15-one 3,11-diacetate inhibits the reaction [Ceruletide results in increased expression of RELA protein]; isoborneol inhibits the reaction [Ceruletide results in decreased phosphorylation of RELA protein] CTD PMID:22982818 PMID:33166053 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 increases cleavage ISO Ceruletide results in increased cleavage of RIPK1 protein CTD PMID:16339139 NCBI chr13:34,002,225...34,035,170
Ensembl chr13:34,002,363...34,037,147
JBrowse link
G Ruvbl1 RuvB-like protein 1 increases expression ISO Ceruletide results in increased expression of RUVBL1 protein CTD PMID:18024178 NCBI chr 6:88,465,409...88,497,566
Ensembl chr 6:88,465,409...88,497,572
JBrowse link
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 increases activity ISO cerulein increases activity of Serpinf1 protein in blood RGD PMID:10423332 RGD:1625538 NCBI chr11:75,410,029...75,422,623
Ensembl chr11:75,409,769...75,422,701
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions
decreases expression
EXP isoborneol inhibits the reaction [Ceruletide results in decreased expression of SOD1 protein] CTD PMID:33166053 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]; [KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein; IL6 protein inhibits the reaction [(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]] CTD PMID:26390243 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
increases secretion
ISO
EXP
Ceruletide results in increased expression of TNF mRNA; Ceruletide results in increased expression of TNF protein
isoborneol inhibits the reaction [Ceruletide results in increased expression of TNF protein]
2-acetoxy-5-(2-4-(trifluoromethyl)phenethylamino)benzoic acid inhibits the reaction [[Ceruletide co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; [Ceruletide co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA; arsenic trioxide inhibits the reaction [Ceruletide results in increased expression of TNF mRNA]; Dietary Fats promotes the reaction [Ceruletide results in increased expression of TNF mRNA]; Dietary Fats promotes the reaction [Ceruletide results in increased secretion of TNF protein]; Pentoxifylline inhibits the reaction [Ceruletide results in increased expression of TNF protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Dietary Fats promotes the reaction [Ceruletide results in increased expression of TNF mRNA]]
CTD PMID:10773043 PMID:17517186 PMID:22575522 PMID:26873426 PMID:33166053 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Ceruletide results in increased expression of TPI1 protein CTD PMID:18024178 NCBI chr 6:124,810,586...124,814,158
Ensembl chr 6:124,810,586...124,814,296
JBrowse link
G Vcp valosin containing protein decreases expression ISO Ceruletide results in decreased expression of VCP protein CTD PMID:18024178 NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507
JBrowse link
G Xbp1 X-box binding protein 1 increases expression
multiple interactions
ISO Ceruletide results in increased expression of XBP1 mRNA alternative form; Ceruletide results in increased expression of XBP1 protein alternative form
Dietary Fats promotes the reaction [Ceruletide results in increased expression of XBP1 mRNA alternative form]; Dietary Fats promotes the reaction [Ceruletide results in increased expression of XBP1 protein alternative form]; Quercetin inhibits the reaction [Ceruletide results in increased expression of XBP1 mRNA alternative form]; Quercetin inhibits the reaction [Ceruletide results in increased expression of XBP1 protein alternative form]
CTD PMID:26873426 NCBI chr11:5,520,641...5,525,993
Ensembl chr11:5,520,659...5,525,893
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases degradation ISO Ceruletide results in increased degradation of XIAP protein CTD PMID:16339139 NCBI chr  X:42,059,613...42,109,664
Ensembl chr  X:42,059,679...42,109,656
JBrowse link
corticotropin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase increases activity ISO Adrenocorticotropic Hormone results in increased activity of ADA protein CTD PMID:8868375 NCBI chr 2:163,726,571...163,750,239
Ensembl chr 2:163,726,584...163,750,239
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha increases abundance ISO CALCA protein results in increased abundance of Adrenocorticotropic Hormone CTD PMID:12639925 NCBI chr 7:114,625,981...114,636,910
Ensembl chr 7:114,631,478...114,636,357
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases activity ISO Adrenocorticotropic Hormone results in decreased activity of CNP protein CTD PMID:3030154 NCBI chr11:100,574,909...100,591,875
Ensembl chr11:100,574,904...100,591,729
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases secretion
ISO Astemizole inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]]; Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]; E 4031 inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]]; Tetraethylammonium promotes the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone] CTD PMID:18835572 NCBI chr 3:19,693,401...19,695,396
Ensembl chr 3:19,693,401...19,695,396
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects abundance ISO CYP17A1 protein affects the abundance of Adrenocorticotropic Hormone CTD PMID:18645707 NCBI chr19:46,667,165...46,673,000
Ensembl chr19:46,667,165...46,673,172
JBrowse link
G Gh growth hormone multiple interactions ISO Adrenocorticotropic Hormone inhibits the reaction [INS protein results in increased secretion of GH1 protein] CTD PMID:3008584 NCBI chr11:106,300,261...106,303,703
Ensembl chr11:106,300,271...106,301,865
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A multiple interactions
affects expression
ISO Bupropion inhibits the reaction [Adrenocorticotropic Hormone affects the expression of HTR2A mRNA] CTD PMID:18239281 NCBI chr14:74,640,874...74,706,859
Ensembl chr14:74,640,840...74,709,494
JBrowse link
G Ins2 insulin II multiple interactions ISO Adrenocorticotropic Hormone inhibits the reaction [INS protein results in increased secretion of GH1 protein] CTD PMID:3008584 NCBI chr 7:142,678,656...142,679,726
Ensembl chr 7:142,678,656...142,743,381
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects abundance ISO NR3C1 gene polymorphism affects the abundance of Adrenocorticotropic Hormone CTD PMID:17716631 NCBI chr18:39,410,545...39,519,421
Ensembl chr18:39,410,545...39,519,421
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory inhibitor subunit 1B multiple interactions EXP Cocaine promotes the reaction [PPP1R1B protein results in increased abundance of Adrenocorticotropic Hormone] CTD PMID:10516482 NCBI chr11:98,348,406...98,357,796
Ensembl chr11:98,348,404...98,357,796
JBrowse link
G Ucn2 urocortin 2 increases abundance EXP UCN2 protein results in increased abundance of Adrenocorticotropic Hormone CTD PMID:16330704 NCBI chr 9:108,986,163...108,987,164
Ensembl chr 9:108,986,010...108,987,164
JBrowse link
cosyntropin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases expression ISO Cosyntropin results in decreased expression of HSD11B2 protein CTD PMID:11082157 NCBI chr 8:105,518,746...105,523,988
Ensembl chr 8:105,518,755...105,523,988
JBrowse link
creatinine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arntl aryl hydrocarbon receptor nuclear translocator-like increases abundance EXP ARNTL gene mutant form results in increased abundance of Creatinine CTD PMID:27056296 NCBI chr 7:113,178,471...113,314,126
Ensembl chr 7:113,207,465...113,314,126
JBrowse link
G Col2a1 collagen, type II, alpha 1 multiple interactions ISO [COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine] CTD PMID:24709313 NCBI chr15:97,975,602...98,004,724
Ensembl chr15:97,975,602...98,004,695
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance
EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Creatinine] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
G Lepr leptin receptor affects abundance
multiple interactions
increases abundance
EXP LEPR affects the abundance of Creatinine
Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Creatinine]
CTD PMID:20567778 PMID:29988851 NCBI chr 4:101,717,137...101,815,352
Ensembl chr 4:101,717,404...101,815,352
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions EXP [NFE2L2 protein affects the susceptibility to ochratoxin A] which results in increased abundance of Creatinine CTD PMID:28710020 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [SC 560 results in decreased activity of PTGS1 protein] which results in increased abundance of Creatinine CTD PMID:19629487 NCBI chr 2:36,216,742...36,258,593
Ensembl chr 2:36,230,426...36,252,272
JBrowse link
G Slc47a1 solute carrier family 47, member 1 multiple interactions ISO Creatinine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,343,400...61,378,842
Ensembl chr11:61,343,401...61,378,345
JBrowse link
G Slc47a2 solute carrier family 47, member 2 multiple interactions ISO Creatinine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,301,627...61,342,860
Ensembl chr11:61,301,631...61,342,860
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial decreases abundance ISO SOD2 protein results in decreased abundance of Creatinine CTD PMID:19917352 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
desmopressin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp2 aquaporin 2 increases expression
multiple interactions
EXP
ISO
Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA; Deamino Arginine Vasopressin results in increased expression of AQP2 protein
Deamino Arginine Vasopressin inhibits the reaction [aluminum lactate results in decreased expression of AQP2 protein]; Deamino Arginine Vasopressin results in increased expression of and results in increased uptake of and results in increased ubiquitination of AQP2 protein
Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA]; Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 protein]
CTD PMID:16495377 PMID:16675087 PMID:21734099 NCBI chr15:99,579,056...99,584,545
Ensembl chr15:99,579,055...99,584,547
JBrowse link
G Avp arginine vasopressin multiple interactions EXP [Atrazine affects the metabolism of AVP protein] which results in increased abundance of Deamino Arginine Vasopressin CTD PMID:33485040 NCBI chr 2:130,580,620...130,582,588
Ensembl chr 2:130,580,620...130,582,554
JBrowse link
G Avpr2 arginine vasopressin receptor 2 multiple interactions ISO [Deamino Arginine Vasopressin binds to and results in increased activity of AVPR2 protein] which results in decreased activity of 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid CTD PMID:1399968 PMID:15685210 NCBI chr  X:73,891,765...73,894,428
Ensembl chr  X:73,892,102...73,895,502
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator increases activity ISO Deamino Arginine Vasopressin results in increased activity of CFTR protein CTD PMID:15685210 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768
JBrowse link
G Cul5 cullin 5 increases expression ISO Deamino Arginine Vasopressin results in increased expression of CUL5 protein CTD PMID:21734099 NCBI chr 9:53,614,581...53,667,507
Ensembl chr 9:53,614,582...53,670,014
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] CTD PMID:20056751 NCBI chr16:38,089,001...38,246,084
Ensembl chr16:38,089,001...38,246,084
JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory increases phosphorylation
multiple interactions
ISO Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein
ML 7 inhibits the reaction [Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein]
CTD PMID:15347643 NCBI chr 2:156,775,408...156,781,657
Ensembl chr 2:156,775,420...156,781,658
JBrowse link
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 increases expression ISO Deamino Arginine Vasopressin results in increased expression of NEDD4 protein CTD PMID:21734099 NCBI chr 9:72,662,331...72,749,851
Ensembl chr 9:72,662,346...72,749,852
JBrowse link
G Scnn1b sodium channel, nonvoltage-gated 1 beta increases expression ISO Deamino Arginine Vasopressin results in increased expression of SCNN1B mRNA CTD PMID:11711512 NCBI chr 7:121,865,038...121,918,728
Ensembl chr 7:121,865,038...121,918,514
JBrowse link
G Scnn1g sodium channel, nonvoltage-gated 1 gamma increases expression ISO Deamino Arginine Vasopressin results in increased expression of SCNN1G mRNA CTD PMID:11711512 NCBI chr 7:121,734,420...121,768,482
Ensembl chr 7:121,734,479...121,768,475
JBrowse link
G Vwf Von Willebrand factor increases activity
increases secretion
ISO Deamino Arginine Vasopressin results in increased activity of VWF protein
Deamino Arginine Vasopressin results in increased secretion of VWF protein
CTD PMID:1837767 PMID:2738447 PMID:3259400 NCBI chr 6:125,552,948...125,686,679
Ensembl chr 6:125,546,774...125,686,679
JBrowse link
dimethyl sulfoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1110051M20Rik RIKEN cDNA 1110051M20 gene affects expression ISO Dimethyl Sulfoxide affects the expression of C11ORF49 mRNA CTD PMID:24834073 NCBI chr 2:91,273,240...91,444,714
Ensembl chr 2:91,275,068...91,444,704
JBrowse link
G 1190005I06Rik RIKEN cDNA 1190005I06 gene affects expression ISO Dimethyl Sulfoxide affects the expression of C16ORF74 mRNA CTD PMID:24834073 NCBI chr 8:120,608,602...120,634,390
Ensembl chr 8:120,608,602...120,647,632
JBrowse link
G 1700008O03Rik RIKEN cDNA 1700008O03 gene affects expression ISO Dimethyl Sulfoxide affects the expression of C19ORF81 mRNA CTD PMID:24834073 NCBI chr 7:44,360,043...44,385,694
Ensembl chr 7:44,360,043...44,385,820
JBrowse link
G A2m alpha-2-macroglobulin increases expression ISO Dimethyl Sulfoxide results in increased expression of A2M mRNA CTD PMID:12883083 NCBI chr 6:121,636,165...121,679,238
Ensembl chr 6:121,635,376...121,679,227
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A affects expression ISO Dimethyl Sulfoxide affects the expression of ABCB1 mRNA CTD PMID:12843640 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:11682029 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 increases expression
decreases expression
ISO Dimethyl Sulfoxide results in increased expression of ACTC1 mRNA
Dimethyl Sulfoxide results in decreased expression of ACTC1 mRNA
CTD PMID:22105179 NCBI chr 2:114,047,282...114,052,875
Ensembl chr 2:114,047,282...114,053,548
JBrowse link
G Agrp agouti related neuropeptide affects expression ISO Dimethyl Sulfoxide affects the expression of AGRP mRNA CTD PMID:24834073 NCBI chr 8:105,566,695...105,579,845
Ensembl chr 8:105,566,698...105,637,393
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
increases expression
decreases expression
ISO
EXP
Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]
Dimethyl Sulfoxide results in increased expression of AHR mRNA; Dimethyl Sulfoxide results in increased expression of AHR protein
AHR protein affects the reaction [Dimethyl Sulfoxide results in increased phosphorylation of MYL2 protein]; Dimethyl Sulfoxide promotes the reaction [AHR protein binds to AHR promoter]; Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]; Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]; Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [AHR protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR mRNA]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR protein]
Dimethyl Sulfoxide results in decreased expression of AHR mRNA
CTD PMID:16675542 PMID:22486318 PMID:33723743 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038
JBrowse link
G Aicda activation-induced cytidine deaminase affects expression ISO Dimethyl Sulfoxide affects the expression of AICDA mRNA CTD PMID:24834073 NCBI chr 6:122,553,809...122,564,180
Ensembl chr 6:122,553,801...122,564,180
JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 multiple interactions
affects localization
EXP Dimethyl Sulfoxide inhibits the reaction [Acetaminophen affects the localization of AIFM1 protein]
Dimethyl Sulfoxide affects the localization of AIFM1 protein
CTD PMID:20423716 PMID:22535522 NCBI chr  X:48,474,944...48,513,563
Ensembl chr  X:48,474,944...48,513,563
JBrowse link
G Alas2 aminolevulinic acid synthase 2, erythroid increases expression EXP Dimethyl Sulfoxide results in increased expression of ALAS2 mRNA CTD PMID:21296123 NCBI chr  X:150,547,417...150,570,622
Ensembl chr  X:150,547,375...150,570,638
JBrowse link
G Alb albumin decreases expression ISO Dimethyl Sulfoxide results in decreased expression of ALB mRNA
Dimethyl Sulfoxide results in decreased expression of ALB mRNA; Dimethyl Sulfoxide results in decreased expression of ALB protein
CTD PMID:14757319 PMID:22105179 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 increases expression ISO Dimethyl Sulfoxide results in increased expression of ALDH1A1 mRNA CTD PMID:22193206 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions EXP [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein] CTD PMID:23751068 NCBI chr 6:116,410,071...116,461,178
Ensembl chr 6:116,410,077...116,461,178
JBrowse link
G Apoa1 apolipoprotein A-I increases expression
increases activity
ISO Dimethyl Sulfoxide results in increased expression of APOA1 mRNA; Dimethyl Sulfoxide results in increased expression of APOA1 protein
Dimethyl Sulfoxide results in increased activity of APOA1 promoter
CTD PMID:16423621 NCBI chr 9:46,228,630...46,230,469
Ensembl chr 9:46,228,580...46,230,466
JBrowse link
G Apom apolipoprotein M affects expression ISO Dimethyl Sulfoxide affects the expression of APOM mRNA CTD PMID:24834073 NCBI chr17:35,128,997...35,131,801
Ensembl chr17:35,128,997...35,132,050
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of AQP1 mRNA CTD PMID:22193206 NCBI chr 6:55,336,299...55,348,555
Ensembl chr 6:55,336,432...55,348,555
JBrowse link
G Ar androgen receptor multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Androgens results in increased activity of AR protein] CTD PMID:28377212 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO
EXP
Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter]
Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]]
CTD PMID:16675542 PMID:33723743 NCBI chr 3:95,434,367...95,497,240
Ensembl chr 3:95,434,388...95,497,240
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 affects expression ISO Dimethyl Sulfoxide affects the expression of ARPC4 mRNA CTD PMID:24834073 NCBI chr 6:113,378,113...113,390,447
Ensembl chr 6:113,378,115...113,390,448
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of ATF3 mRNA CTD PMID:22193206 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039
JBrowse link
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide increases expression ISO Dimethyl Sulfoxide results in increased expression of ATP1A2 mRNA CTD PMID:22193206 NCBI chr 1:172,271,709...172,298,064
Ensembl chr 1:172,271,709...172,298,064
JBrowse link
G Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide increases expression ISO Dimethyl Sulfoxide results in increased expression of ATP1B1 mRNA CTD PMID:22193206 NCBI chr 1:164,437,099...164,458,355
Ensembl chr 1:164,437,109...164,458,355
JBrowse link
G Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide increases expression ISO Dimethyl Sulfoxide results in increased expression of ATP1B3 mRNA CTD PMID:22193206 NCBI chr 9:96,332,655...96,364,431
Ensembl chr 9:96,332,655...96,364,442
JBrowse link
G Atp5j2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 affects expression ISO Dimethyl Sulfoxide affects the expression of ATP5MF mRNA CTD PMID:24834073 NCBI chr 5:145,183,704...145,191,541
Ensembl chr 5:145,183,698...145,192,062
JBrowse link
G Aurkaip1 aurora kinase A interacting protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of AURKAIP1 mRNA CTD PMID:24834073 NCBI chr 4:155,831,269...155,833,098
Ensembl chr 4:155,831,272...155,833,130
JBrowse link
G Barhl2 BarH like homeobox 2 affects expression ISO Dimethyl Sulfoxide affects the expression of BARHL2 mRNA CTD PMID:24834073 NCBI chr 5:106,452,523...106,458,166
Ensembl chr 5:106,452,523...106,458,166
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of BAX mRNA
Quercetin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of BAX mRNA]
CTD PMID:17652743 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bend6 BEN domain containing 6 affects expression ISO Dimethyl Sulfoxide affects the expression of BEND6 mRNA CTD PMID:24834073 NCBI chr 1:33,852,052...33,907,933
Ensembl chr 1:33,852,052...33,907,816
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of BTG2 mRNA CTD PMID:22193206 NCBI chr 1:134,074,865...134,079,155
Ensembl chr 1:134,075,170...134,079,120
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 5:31,054,620...31,078,479
Ensembl chr 5:31,054,780...31,078,479
JBrowse link
G Cadm1 cell adhesion molecule 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of CADM1 mRNA CTD PMID:22193206 NCBI chr 9:47,530,170...47,862,280
Ensembl chr 9:47,530,173...47,857,637
Ensembl chr 9:47,530,173...47,857,637
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO
EXP
Dimethyl Sulfoxide results in decreased cleavage of and results in decreased activity of CASP3 protein
Dimethyl Sulfoxide results in increased cleavage of CASP3 protein
CTD PMID:12370186 PMID:22535522 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cat catalase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of CAT mRNA] CTD PMID:9169468 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions
increases secretion
decreases expression
ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Dimethyl Sulfoxide results in increased secretion of CCL2 protein]
Dimethyl Sulfoxide results in decreased expression of CCL2 mRNA
Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of CCL2 mRNA]
CTD PMID:10925121 PMID:14576080 PMID:15689417 PMID:17529908 PMID:21878375 More... NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl28 chemokine (C-C motif) ligand 28 affects expression ISO Dimethyl Sulfoxide affects the expression of CCL28 mRNA CTD PMID:24834073 NCBI chr13:119,623,819...119,654,359
Ensembl chr13:119,623,819...119,654,359
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein] CTD PMID:21878375 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Cd14 CD14 antigen increases expression ISO Dimethyl Sulfoxide results in increased expression of CD14 protein CTD PMID:26036281 NCBI chr18:36,725,064...36,726,815
Ensembl chr18:36,725,067...36,726,798
JBrowse link
G Cd38 CD38 antigen multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]] CTD PMID:15964820 NCBI chr 5:43,868,809...43,912,374
Ensembl chr 5:43,868,553...43,912,375
JBrowse link
G Cd3g CD3 antigen, gamma polypeptide affects expression ISO Dimethyl Sulfoxide affects the expression of CD3G mRNA CTD PMID:24834073 NCBI chr 9:44,969,572...44,980,431
Ensembl chr 9:44,969,572...44,980,431
JBrowse link
G Cd59b CD59b antigen multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased mutagenesis of CD59 gene]; Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased mutagenesis of CD59 gene] CTD PMID:12361925 PMID:15033018 NCBI chr 2:104,069,781...104,085,790
Ensembl chr 2:104,069,849...104,091,187
JBrowse link
G Cdc25b cell division cycle 25B decreases expression EXP Dimethyl Sulfoxide results in decreased expression of CDC25B mRNA CTD PMID:21296123 NCBI chr 2:131,186,436...131,198,511
Ensembl chr 2:131,186,949...131,198,497
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of CDH1 mRNA CTD PMID:22193206 NCBI chr 8:106,603,350...106,670,247
Ensembl chr 8:106,603,351...106,670,246
JBrowse link
G Ceacam19 carcinoembryonic antigen-related cell adhesion molecule 19 affects expression ISO Dimethyl Sulfoxide affects the expression of CEACAM19 mRNA CTD PMID:24834073 NCBI chr 7:19,875,742...19,887,990
Ensembl chr 7:19,875,742...19,887,965
JBrowse link
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta increases expression ISO Dimethyl Sulfoxide results in increased expression of CEBPB mRNA CTD PMID:22193206 NCBI chr 2:167,688,915...167,690,432
Ensembl chr 2:167,688,915...167,690,418
JBrowse link
G Cfap300 cilia and flagella associated protein 300 affects expression ISO Dimethyl Sulfoxide affects the expression of CFAP300 mRNA CTD PMID:24834073 NCBI chr 9:8,021,672...8,042,875
Ensembl chr 9:8,021,672...8,042,823
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression ISO Dimethyl Sulfoxide affects the expression of CFLAR mRNA CTD PMID:24834073 NCBI chr 1:58,711,311...58,758,884
Ensembl chr 1:58,711,508...58,758,884
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CGREF1 mRNA CTD PMID:24834073 NCBI chr 5:30,933,143...30,945,480
Ensembl chr 5:30,933,143...30,945,591
JBrowse link
G Chek2 checkpoint kinase 2 affects expression ISO Dimethyl Sulfoxide affects the expression of CHEK2 mRNA CTD PMID:24834073 NCBI chr 5:110,839,800...110,874,140
Ensembl chr 5:110,839,979...110,874,145
JBrowse link
G Cklf chemokine-like factor affects expression ISO Dimethyl Sulfoxide affects the expression of CKLF mRNA CTD PMID:24834073 NCBI chr 8:104,250,861...104,266,010
Ensembl chr 8:104,250,861...104,264,938
JBrowse link
G Cldn6 claudin 6 multiple interactions
decreases methylation
increases expression
ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN6 mRNA]
Dimethyl Sulfoxide results in decreased methylation of CLDN6 promoter
Dimethyl Sulfoxide results in increased expression of CLDN6 mRNA
CTD PMID:18661270 NCBI chr17:23,679,348...23,682,446
Ensembl chr17:23,679,249...23,682,446
JBrowse link
G Cldn8 claudin 8 increases expression ISO Dimethyl Sulfoxide results in increased expression of CLDN8 mRNA CTD PMID:18661270 NCBI chr16:88,560,826...88,563,183
Ensembl chr16:88,560,828...88,563,183
JBrowse link
G Cldn9 claudin 9 multiple interactions
increases expression
decreases methylation
ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN9 mRNA]
Dimethyl Sulfoxide results in increased expression of CLDN9 mRNA
Dimethyl Sulfoxide results in decreased methylation of CLDN9 promoter
CTD PMID:18661270 NCBI chr17:23,682,584...23,684,026
Ensembl chr17:23,682,584...23,684,026
JBrowse link
G Cntf ciliary neurotrophic factor affects expression ISO Dimethyl Sulfoxide affects the expression of CNTF mRNA CTD PMID:24834073 NCBI chr19:12,763,528...12,765,632
Ensembl chr19:12,763,660...12,765,632
JBrowse link
G Col11a1 collagen, type XI, alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of COL11A1 mRNA CTD PMID:22193206 NCBI chr 3:114,030,479...114,220,756
Ensembl chr 3:114,030,540...114,220,718
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein] CTD PMID:11682029 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Col4a1 collagen, type IV, alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of COL4A1 mRNA CTD PMID:22193206 NCBI chr 8:11,198,423...11,312,889
Ensembl chr 8:11,198,423...11,312,826
JBrowse link
G Col4a5 collagen, type IV, alpha 5 increases expression ISO Dimethyl Sulfoxide results in increased expression of COL4A5 mRNA CTD PMID:22193206 NCBI chr  X:141,475,370...141,689,236
Ensembl chr  X:141,475,385...141,689,234
JBrowse link
G Col5a1 collagen, type V, alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of COL5A1 mRNA CTD PMID:22193206 NCBI chr 2:27,886,381...28,039,510
Ensembl chr 2:27,886,425...28,039,514
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4I1 increases expression ISO Dimethyl Sulfoxide results in increased expression of COX4I1 protein CTD PMID:27385396 NCBI chr 8:120,668,225...120,674,209
Ensembl chr 8:120,668,222...120,674,207
JBrowse link
G Cp ceruloplasmin increases expression ISO Dimethyl Sulfoxide results in increased expression of CP mRNA CTD PMID:22193206 NCBI chr 3:19,956,933...20,009,750
Ensembl chr 3:19,957,054...20,009,145
JBrowse link
G Cpm carboxypeptidase M increases expression ISO Dimethyl Sulfoxide results in increased expression of CPM mRNA CTD PMID:22193206 NCBI chr10:117,629,500...117,687,352
Ensembl chr10:117,629,500...117,687,352
JBrowse link
G Cs citrate synthase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr10:128,337,727...128,362,482
Ensembl chr10:128,337,734...128,362,479
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Dimethyl Sulfoxide results in increased expression of CSF1R mRNA CTD PMID:8445950 NCBI chr18:61,105,572...61,131,139
Ensembl chr18:61,100,598...61,132,149
JBrowse link
G Cth cystathionase (cystathionine gamma-lyase) affects expression ISO Dimethyl Sulfoxide affects the expression of CTH mRNA CTD PMID:24834073 NCBI chr 3:157,894,248...157,925,081
Ensembl chr 3:157,894,248...157,925,077
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of CTNNB1 protein CTD PMID:20091315 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Cuta cutA divalent cation tolerance homolog affects expression ISO Dimethyl Sulfoxide affects the expression of CUTA mRNA CTD PMID:24834073 NCBI chr17:26,937,972...26,939,884
Ensembl chr17:26,933,819...26,939,569
JBrowse link
G Cxcl14 chemokine (C-X-C motif) ligand 14 affects expression ISO Dimethyl Sulfoxide affects the expression of CXCL14 mRNA CTD PMID:24834073 NCBI chr13:56,288,643...56,296,811
Ensembl chr13:56,288,643...56,296,551
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions
decreases expression
increases expression
ISO [Dimethyl Sulfoxide co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]
Dimethyl Sulfoxide results in decreased expression of CXCL8 mRNA
Dimethyl Sulfoxide results in increased expression of CXCL8 mRNA
CTD PMID:8969274 PMID:10022265 PMID:17529908 PMID:18684396 PMID:24296301 More... NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxxc4 CXXC finger 4 affects expression ISO Dimethyl Sulfoxide affects the expression of CXXC4 mRNA CTD PMID:24834073 NCBI chr 3:134,236,144...134,262,163
Ensembl chr 3:134,236,484...134,262,161
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [adrenocorticotropin zinc results in decreased expression of CYP11B2 mRNA]; Dimethyl Sulfoxide promotes the reaction [adrenocorticotropin zinc results in decreased activity of CYP11B2 protein] CTD PMID:10822027 NCBI chr15:74,834,892...74,841,643
Ensembl chr15:74,834,125...74,841,643
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects expression
multiple interactions
increases expression
ISO
EXP
Dimethyl Sulfoxide affects the expression of CYP1A1 mRNA
JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of CYP1A1 protein]
Dimethyl Sulfoxide results in increased expression of CYP1A1; Dimethyl Sulfoxide results in increased expression of CYP1A1 protein
Dimethyl Sulfoxide results in increased expression of CYP1A1 mRNA; Dimethyl Sulfoxide results in increased expression of CYP1A1 protein
Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]
CTD PMID:12147272 PMID:12843640 PMID:22486318 PMID:31096615 PMID:33723743 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression
increases expression
multiple interactions
ISO Dimethyl Sulfoxide affects the expression of CYP1A2 mRNA
Dimethyl Sulfoxide results in increased expression of CYP1A2 mRNA
[hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP1A2
CTD PMID:12843640 PMID:18347083 PMID:30262279 NCBI chr 9:57,676,937...57,683,655
Ensembl chr 9:57,676,937...57,683,703
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects expression
increases expression
ISO
EXP
Dimethyl Sulfoxide affects the expression of CYP1B1 mRNA
Dimethyl Sulfoxide results in increased expression of CYP1B1 protein
CTD PMID:12843640 PMID:33723743 NCBI chr17:79,706,940...79,715,061
Ensembl chr17:79,701,537...79,715,061
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]] CTD PMID:15964820 NCBI chr 1:74,713,148...74,737,897
Ensembl chr 1:74,713,574...74,737,892
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 affects expression ISO Dimethyl Sulfoxide affects the expression of CYP2A6 mRNA CTD PMID:12843640 NCBI chr 7:26,835,339...26,843,264
Ensembl chr 7:26,835,305...26,843,548
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
increases expression
ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [CYP2B1 protein results in increased metabolism of 7-benzyloxy-4-trifluoromethylcoumarin]
Dimethyl Sulfoxide results in increased expression of CYP2B6 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2B6 protein
[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]
CTD PMID:19858067 PMID:20371638 PMID:30262279 PMID:31096615 NCBI chr 7:25,897,658...25,926,624
Ensembl chr 7:25,897,620...25,926,624
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr19:39,389,556...39,463,103
Ensembl chr19:39,389,556...39,463,075
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr19:38,976,662...39,003,627
Ensembl chr19:38,976,647...39,003,289
JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 multiple interactions EXP [Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA; [Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] CTD PMID:20371638 NCBI chr19:39,006,940...39,042,690
Ensembl chr19:39,007,019...39,042,693
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]] CTD PMID:11368792 NCBI chr15:82,370,527...82,380,260
Ensembl chr15:82,370,527...82,380,260
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression
increases expression
increases activity
multiple interactions
ISO
EXP
Dimethyl Sulfoxide affects the expression of CYP2E1 mRNA
Dimethyl Sulfoxide results in increased expression of CYP2E1 protein
Dimethyl Sulfoxide results in increased activity of CYP2E1 protein
Dimethyl Sulfoxide binds to and results in increased expression of CYP2E1 protein; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]
Dimethyl Sulfoxide results in increased expression of CYP2E1 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2E1 protein
Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]
CTD PMID:1538706 PMID:3113478 PMID:3337723 PMID:8074729 PMID:9143349 More... NCBI chr 7:140,763,819...140,774,990
Ensembl chr 7:140,763,739...140,774,987
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 affects expression ISO Dimethyl Sulfoxide affects the expression of CYP3A5 mRNA CTD PMID:12843640 NCBI chr 5:145,854,607...145,879,854
Ensembl chr 5:145,854,426...145,879,964
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 affects expression ISO Dimethyl Sulfoxide affects the expression of CYP3A7 mRNA CTD PMID:12843640 NCBI chr 5:137,892,933...137,925,610
Ensembl chr 5:137,892,932...137,921,619
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 increases expression ISO DMSO increases expression of Cyp7a1 mRNA in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Cysrt1 cysteine rich tail 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CYSRT1 mRNA CTD PMID:24834073 NCBI chr 2:25,238,819...25,239,897
Ensembl chr 2:25,238,818...25,242,452
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of DDIT3 mRNA CTD PMID:22193206 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Depp1 DEPP1 autophagy regulator affects expression ISO Dimethyl Sulfoxide affects the expression of DEPP1 mRNA CTD PMID:24834073 NCBI chr 6:116,650,684...116,652,847
Ensembl chr 6:116,650,609...116,652,794
JBrowse link
G Dffa DNA fragmentation factor, alpha subunit increases cleavage EXP Dimethyl Sulfoxide results in increased cleavage of DFFA protein CTD PMID:22535522 NCBI chr 4:149,104,142...149,120,653
Ensembl chr 4:149,104,146...149,120,647
JBrowse link
G Dmap1 DNA methyltransferase 1-associated protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of DMAP1 mRNA CTD PMID:24834073 NCBI chr 4:117,674,681...117,682,321
Ensembl chr 4:117,674,681...117,682,273
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression ISO Dimethyl Sulfoxide results in increased expression of DNAJB5 mRNA CTD PMID:22193206 NCBI chr 4:42,949,867...42,959,425
Ensembl chr 4:42,949,814...42,959,425
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Dimethyl Sulfoxide results in increased expression of DNAJB9 mRNA CTD PMID:22193206 NCBI chr12:44,205,897...44,210,068
Ensembl chr12:44,205,559...44,210,326
JBrowse link
G Dnmt1 DNA methyltransferase (cytosine-5) 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of DNMT1 protein CTD PMID:17065238 NCBI chr 9:20,907,206...20,959,888
Ensembl chr 9:20,907,209...20,959,888
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of DUSP1 mRNA CTD PMID:22193206 NCBI chr17:26,505,591...26,508,472
Ensembl chr17:26,505,590...26,562,128
JBrowse link
G Eaf2 ELL associated factor 2 affects expression ISO Dimethyl Sulfoxide affects the expression of EAF2 mRNA CTD PMID:24834073 NCBI chr16:36,792,884...36,875,068
Ensembl chr16:36,792,884...36,875,003
JBrowse link
G Edn2 endothelin 2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of EDN2 mRNA CTD PMID:15619356 NCBI chr 4:120,161,206...120,167,360
Ensembl chr 4:120,161,206...120,167,360
JBrowse link
G Ednra endothelin receptor type A multiple interactions ISO [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA protein; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA protein CTD PMID:20561571 NCBI chr 8:77,663,029...77,724,452
Ensembl chr 8:77,663,031...77,724,464
JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]
Dimethyl Sulfoxide results in increased expression of EDNRB mRNA; Dimethyl Sulfoxide results in increased expression of EDNRB protein
CTD PMID:20561571 NCBI chr14:103,814,615...103,844,508
Ensembl chr14:103,814,625...103,844,402
JBrowse link
G Eef1akmt1 EEF1A alpha lysine methyltransferase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of EEF1AKMT1 mRNA CTD PMID:24834073 NCBI chr14:57,549,595...57,571,582
Ensembl chr14:57,549,597...57,571,612
JBrowse link
G Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of EFEMP1 mRNA CTD PMID:22193206 NCBI chr11:28,853,154...28,926,743
Ensembl chr11:28,853,204...28,926,743
JBrowse link
G Egr1 early growth response 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of EGR1 mRNA CTD PMID:22193206 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of EIF4G2 protein CTD PMID:18491231 NCBI chr 7:111,067,985...111,083,030
Ensembl chr 7:111,067,750...111,083,030
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of EMP1 mRNA CTD PMID:22193206 NCBI chr 6:135,362,550...135,383,173
Ensembl chr 6:135,362,545...135,383,173
JBrowse link
G Endog endonuclease G affects localization EXP Dimethyl Sulfoxide affects the localization of ENDOG protein CTD PMID:22535522 NCBI chr 2:30,171,408...30,174,069
Ensembl chr 2:30,171,493...30,174,069
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of ENPP2 protein CTD PMID:22952646 NCBI chr15:54,838,901...54,952,789
Ensembl chr15:54,838,901...54,952,892
JBrowse link
G Eppin epididymal peptidase inhibitor affects expression ISO Dimethyl Sulfoxide affects the expression of EPPIN mRNA CTD PMID:24834073 NCBI chr 2:164,588,343...164,593,571
Ensembl chr 2:164,588,343...164,593,594
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Eva1b eva-1 homolog B (C. elegans) affects expression ISO Dimethyl Sulfoxide affects the expression of EVA1B mRNA CTD PMID:24834073 NCBI chr 4:126,145,709...126,149,875
Ensembl chr 4:126,147,744...126,149,875
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) increases expression ISO Dimethyl Sulfoxide results in increased expression of FAS protein CTD PMID:15998540 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) decreases expression ISO Dimethyl Sulfoxide results in decreased expression of FASLG mRNA CTD PMID:10925121 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Fbxl21 F-box and leucine-rich repeat protein 21 affects expression ISO Dimethyl Sulfoxide affects the expression of FBXL21P mRNA CTD PMID:24834073 NCBI chr13:56,522,388...56,537,898
Ensembl chr13:56,522,472...56,537,898
JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO Dimethyl Sulfoxide results in increased expression of FGG mRNA; Dimethyl Sulfoxide results in increased expression of FGG protein CTD PMID:14757319 NCBI chr 3:83,007,724...83,015,056
Ensembl chr 3:83,007,724...83,015,049
JBrowse link
G Flnc filamin C, gamma increases expression ISO Dimethyl Sulfoxide results in increased expression of FLNC mRNA CTD PMID:22193206 NCBI chr 6:29,433,153...29,461,889
Ensembl chr 6:29,433,256...29,461,883
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:68,678,536...68,717,963
Ensembl chr  X:68,678,541...68,717,963
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO Dimethyl Sulfoxide results in increased expression of FOS mRNA CTD PMID:22193206 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of FOXA2 mRNA CTD PMID:22105179 NCBI chr 2:148,042,877...148,046,969
Ensembl chr 2:148,042,877...148,046,969
JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 affects expression ISO Dimethyl Sulfoxide affects the expression of FRS3 mRNA CTD PMID:24834073 NCBI chr17:47,687,607...47,704,286
Ensembl chr17:47,689,030...47,704,286
JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GAD1 mRNA CTD PMID:17065238 NCBI chr 2:70,561,303...70,602,014
Ensembl chr 2:70,553,072...70,602,014
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha affects expression ISO Dimethyl Sulfoxide affects the expression of GADD45A mRNA CTD PMID:24834073 NCBI chr 6:67,035,096...67,037,407
Ensembl chr 6:67,035,096...67,037,457
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma increases expression ISO Dimethyl Sulfoxide results in increased expression of GADD45G mRNA CTD PMID:22193206 NCBI chr13:51,846,675...51,848,475
Ensembl chr13:51,846,678...51,848,468
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression ISO Dimethyl Sulfoxide affects the expression of GAPDH mRNA CTD PMID:12843640 NCBI chr 6:125,161,852...125,166,467
Ensembl chr 6:125,161,715...125,166,467
JBrowse link
G Gata4 GATA binding protein 4 decreases expression
increases expression
ISO Dimethyl Sulfoxide results in decreased expression of GATA4 mRNA
Dimethyl Sulfoxide results in increased expression of GATA4 mRNA
CTD PMID:22105179 NCBI chr14:63,198,914...63,271,712
Ensembl chr14:63,198,922...63,271,692
JBrowse link
G Gata6 GATA binding protein 6 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of GATA6 mRNA CTD PMID:22105179 NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GJA1 mRNA CTD PMID:22193206 NCBI chr10:56,377,300...56,390,419
Ensembl chr10:56,377,330...56,402,513
JBrowse link
G Gjb1 gap junction protein, beta 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GJB1 mRNA CTD PMID:8631141 NCBI chr  X:101,376,376...101,385,629
Ensembl chr  X:101,376,378...101,385,629
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of GJB2 mRNA CTD PMID:8631141 NCBI chr14:57,098,602...57,104,702
Ensembl chr14:57,098,600...57,104,702
JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of GLT8D1 mRNA CTD PMID:24834073 NCBI chr14:31,001,197...31,012,441
Ensembl chr14:31,001,400...31,011,991
JBrowse link
G Gm32168 predicted gene, 32168 affects expression ISO Dimethyl Sulfoxide affects the expression of TSNARE1 mRNA CTD PMID:24834073 NCBI chr15:74,413,122...74,487,646 JBrowse link
G Gm4756 predicted gene 4756 affects expression ISO Dimethyl Sulfoxide affects the expression of SFTA3 mRNA CTD PMID:24834073 NCBI chr12:72,620,119...72,629,021
Ensembl chr12:72,576,002...72,649,661
JBrowse link
G Gng3 guanine nucleotide binding protein (G protein), gamma 3 affects expression ISO Dimethyl Sulfoxide affects the expression of GNG3 mRNA CTD PMID:24834073 NCBI chr19:8,836,929...8,839,246
Ensembl chr19:8,836,933...8,839,194
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 decreases expression ISO DMSO decreases expression of Gpbar1 protein in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 1:74,278,600...74,279,589
Ensembl chr 1:74,278,550...74,279,624
JBrowse link
G Gpr75 G protein-coupled receptor 75 affects expression ISO Dimethyl Sulfoxide affects the expression of GPR75 mRNA CTD PMID:24834073 NCBI chr11:30,884,633...30,896,090
Ensembl chr11:30,885,358...30,893,729
JBrowse link
G Grn granulin increases expression ISO Dimethyl Sulfoxide results in increased expression of GRN mRNA CTD PMID:16873554 NCBI chr11:102,430,507...102,436,809
Ensembl chr11:102,430,315...102,437,048
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 affects expression ISO Dimethyl Sulfoxide affects the expression of GSTK1 mRNA CTD PMID:24834073 NCBI chr 6:42,245,935...42,250,441
Ensembl chr 6:42,245,935...42,250,447
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein] CTD PMID:12370186 NCBI chr 3:108,012,250...108,017,973
Ensembl chr 3:108,012,255...108,017,973
JBrowse link
G Gstm2 glutathione S-transferase, mu 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of GSTM2 mRNA CTD PMID:22193206 NCBI chr 3:107,981,702...107,986,420
Ensembl chr 3:107,981,702...107,986,453
JBrowse link
G H1f3 H1.3 linker histone, cluster member affects expression ISO Dimethyl Sulfoxide affects the expression of H1-3 mRNA CTD PMID:24834073 NCBI chr13:23,555,032...23,555,807
Ensembl chr13:23,553,262...23,560,686
JBrowse link
G H2-Ea histocompatibility 2, class II antigen E alpha decreases expression ISO Dimethyl Sulfoxide results in decreased expression of HLA-DRA mRNA CTD PMID:21878375 NCBI chr17:34,341,952...34,344,645
Ensembl chr17:34,341,959...34,344,645
JBrowse link
G H2ac7 H2A clustered histone 7 affects expression ISO Dimethyl Sulfoxide affects the expression of H2AC17 mRNA CTD PMID:24834073 NCBI chr13:23,574,381...23,574,915
Ensembl chr13:23,574,381...23,574,952
JBrowse link
G H2bc22 H2B clustered histone 22 affects expression ISO Dimethyl Sulfoxide affects the expression of H2BC17 mRNA CTD PMID:24834073 NCBI chr13:21,787,483...21,801,561
Ensembl chr13:21,787,461...21,789,213
JBrowse link
G H3c10 H3 clustered histone 10 affects expression ISO Dimethyl Sulfoxide affects the expression of H3C6 mRNA CTD PMID:24834073 NCBI chr13:21,717,628...21,718,115
Ensembl chr13:21,717,659...21,718,069
JBrowse link
G H3f4 H3.4 histone multiple interactions
decreases methylation
ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H3-4 protein]
Dimethyl Sulfoxide results in decreased methylation of H3-4 protein
CTD PMID:15964820 NCBI chr11:58,961,711...58,962,273
Ensembl chr11:58,961,812...58,962,222
JBrowse link
G H4f16 H4 histone 16 multiple interactions
increases methylation
ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4-16 protein modified form binds to TGM2 gene]; [Dimethyl Sulfoxide co-treated with Alitretinoin] results in increased methylation of H4-16 protein; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H4-16 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H4-16 protein]]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide results in increased methylation of H4-16 protein] CTD PMID:15964820 NCBI chr 6:136,803,993...136,804,431
Ensembl chr 6:136,801,553...136,804,415
JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 decreases expression
increases expression
ISO Dimethyl Sulfoxide results in decreased expression of HAND1 mRNA
Dimethyl Sulfoxide results in increased expression of HAND1 mRNA
CTD PMID:22105179 NCBI chr11:57,828,713...57,832,147
Ensembl chr11:57,828,705...57,832,818
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain increases expression EXP Dimethyl Sulfoxide results in increased expression of HBB mRNA CTD PMID:21296123
G Hcar1 hydrocarboxylic acid receptor 1 affects expression ISO Dimethyl Sulfoxide affects the expression of HCAR1 mRNA CTD PMID:24834073 NCBI chr 5:123,876,739...123,880,003
Ensembl chr 5:123,876,736...123,880,020
JBrowse link
G Hexim1 hexamethylene bis-acetamide inducible 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of HEXIM1 mRNA; Dimethyl Sulfoxide results in increased expression of HEXIM1 protein CTD PMID:16222702 NCBI chr11:103,116,325...103,119,725
Ensembl chr11:103,116,231...103,119,725
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression ISO Dimethyl Sulfoxide results in increased expression of HIF1A mRNA CTD PMID:22193206 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
increases expression
ISO Dimethyl Sulfoxide results in decreased expression of HMOX1 protein
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]; Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]
Dimethyl Sulfoxide results in increased expression of HMOX1 mRNA
CTD PMID:15689417 PMID:22118543 PMID:22193206 PMID:26497626 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hp haptoglobin increases expression ISO Dimethyl Sulfoxide results in increased expression of HP mRNA; Dimethyl Sulfoxide results in increased expression of HP protein CTD PMID:14757319 NCBI chr 8:109,575,128...109,579,172
Ensembl chr 8:109,575,128...109,579,172
JBrowse link
G Hprt hypoxanthine guanine phosphoribosyl transferase decreases expression ISO Dimethyl Sulfoxide results in decreased expression of HPRT1 mRNA CTD PMID:12883083 NCBI chr  X:52,988,078...53,021,660
Ensembl chr  X:52,988,137...53,021,659
JBrowse link
G Hras Harvey rat sarcoma virus oncogene affects expression ISO Dimethyl Sulfoxide affects the expression of HRAS mRNA CTD PMID:24834073 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Hspa1a heat shock protein 1A increases expression ISO Dimethyl Sulfoxide results in increased expression of HSPA1A mRNA CTD PMID:22193206 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein] CTD PMID:18539414 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Ier2 immediate early response 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of IER2 mRNA CTD PMID:22193206 NCBI chr 8:84,661,331...84,662,852
Ensembl chr 8:84,661,331...84,662,854
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein] CTD PMID:21878375 PMID:29594315 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA] CTD PMID:21878375 NCBI chr10:19,591,949...19,610,229
Ensembl chr10:19,591,949...19,610,229
JBrowse link
G Ift81 intraflagellar transport 81 affects expression ISO Dimethyl Sulfoxide affects the expression of IFT81 mRNA CTD PMID:24834073 NCBI chr 5:122,540,265...122,614,546
Ensembl chr 5:122,550,204...122,614,518
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] CTD PMID:21878375 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1B mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
Dimethyl Sulfoxide results in decreased expression of IL1B mRNA
CTD PMID:21878375 PMID:29594315 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il1r1 interleukin 1 receptor, type I decreases expression ISO Dimethyl Sulfoxide results in decreased expression of IL1R1 mRNA CTD PMID:21878375 NCBI chr 1:40,222,480...40,316,201
Ensembl chr 1:40,225,080...40,317,257
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 3:37,120,713...37,125,954
Ensembl chr 3:37,120,523...37,125,959
JBrowse link
G Il23a interleukin 23, alpha subunit p19 affects expression ISO Dimethyl Sulfoxide affects the expression of IL23A mRNA CTD PMID:24834073 NCBI chr10:128,296,140...128,298,084
Ensembl chr10:128,296,139...128,298,752
JBrowse link
G Il4 interleukin 4 multiple interactions EXP [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA] CTD PMID:23751068 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il5 interleukin 5 multiple interactions EXP [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA] CTD PMID:23751068 NCBI chr11:53,720,794...53,725,103
Ensembl chr11:53,720,794...53,725,106
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
ISO Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
Dimethyl Sulfoxide results in decreased secretion of IL6 protein
Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of IL6 mRNA]
CTD PMID:9378980 PMID:10022265 PMID:15689417 PMID:21878375 PMID:24296301 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 affects expression ISO Dimethyl Sulfoxide affects the expression of IRGM mRNA CTD PMID:24834073 NCBI chr11:48,865,245...48,871,420
Ensembl chr11:48,861,968...48,871,683
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression ISO Dimethyl Sulfoxide affects the expression of ISG15 mRNA CTD PMID:24834073 NCBI chr 4:156,199,424...156,200,818
Ensembl chr 4:156,199,455...156,200,796
JBrowse link
G Itgam integrin alpha M multiple interactions
increases expression
ISO [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of ITGAM protein; Dexamethasone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of ITGAM protein]; Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAM protein] CTD PMID:7909661 PMID:15964820 PMID:16617325 PMID:22118543 PMID:26330309 NCBI chr 7:128,062,640...128,118,491
Ensembl chr 7:128,062,640...128,118,491
JBrowse link
G Itgax integrin alpha X multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAX protein] CTD PMID:15964820 NCBI chr 7:128,129,526...128,150,657
Ensembl chr 7:128,129,547...128,150,657
JBrowse link
G Itgb2 integrin beta 2 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGB2 protein] CTD PMID:15964820 NCBI chr10:77,530,329...77,565,708
Ensembl chr10:77,530,252...77,565,708
JBrowse link
G Jdp2 Jun dimerization protein 2 multiple interactions EXP Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [AHR protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR mRNA]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR protein]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of CYP1A1 protein] CTD PMID:33723743 NCBI chr12:85,598,656...85,639,878
Ensembl chr12:85,599,027...85,639,878
JBrowse link
G Jun jun proto-oncogene increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of JUN mRNA
Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of JUN mRNA]
CTD PMID:7662713 PMID:22193206 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Klf2 Kruppel-like factor 2 (lung) increases expression ISO Dimethyl Sulfoxide results in increased expression of KLF2 mRNA CTD PMID:22193206 NCBI chr 8:72,319,062...72,321,654
Ensembl chr 8:72,319,033...72,321,656
JBrowse link
G Klf4 Kruppel-like factor 4 (gut) increases expression ISO Dimethyl Sulfoxide results in increased expression of KLF4 mRNA CTD PMID:22193206 NCBI chr 4:55,527,137...55,532,475
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Klhl41 kelch-like 41 affects expression ISO Dimethyl Sulfoxide affects the expression of KLHL41 mRNA CTD PMID:24834073 NCBI chr 2:69,670,120...69,684,239
Ensembl chr 2:69,670,120...69,684,230
JBrowse link
G Krt15 keratin 15 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of KRT15 mRNA CTD PMID:22105179 NCBI chr11:100,131,759...100,135,949
Ensembl chr11:100,131,758...100,135,928
JBrowse link
G Lama1 laminin, alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of LAMA1 mRNA CTD PMID:22193206 NCBI chr17:67,697,127...67,822,645
Ensembl chr17:67,697,259...67,822,647
JBrowse link
G Lamb2 laminin, beta 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of LAMB2 mRNA CTD PMID:22193206 NCBI chr 9:108,479,847...108,490,530
Ensembl chr 9:108,479,736...108,490,530
JBrowse link
G Ldhc lactate dehydrogenase C affects expression ISO Dimethyl Sulfoxide affects the expression of LDHC mRNA CTD PMID:24834073 NCBI chr 7:46,861,263...46,878,147
Ensembl chr 7:46,861,203...46,878,142
JBrowse link
G Lgals1 lectin, galactose binding, soluble 1 affects expression ISO Dimethyl Sulfoxide affects the expression of LGALS1 mRNA CTD PMID:24834073 NCBI chr15:78,926,725...78,930,465
Ensembl chr15:78,926,725...78,930,465
JBrowse link
G Llgl2 LLGL2 scribble cell polarity complex component affects expression ISO Dimethyl Sulfoxide affects the expression of LLGL2 mRNA CTD PMID:24834073 NCBI chr11:115,824,029...115,855,780
Ensembl chr11:115,824,049...115,855,780
JBrowse link
G Lrrc4 leucine rich repeat containing 4 affects expression ISO Dimethyl Sulfoxide affects the expression of LRRC4 mRNA CTD PMID:24834073 NCBI chr 6:28,828,126...28,831,747
Ensembl chr 6:28,661,831...28,831,747
JBrowse link
G Ltc4s leukotriene C4 synthase multiple interactions EXP [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA] CTD PMID:23751068 NCBI chr11:50,236,461...50,238,532
Ensembl chr11:50,236,461...50,238,616
JBrowse link
G Lyrm9 LYR motif containing 9 affects expression ISO Dimethyl Sulfoxide affects the expression of LYRM9 mRNA CTD PMID:24834073 NCBI chr11:78,826,595...78,843,899
Ensembl chr11:78,826,584...78,846,870
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions
increases expression
ISO cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K1 mRNA] CTD PMID:31265865 NCBI chr 9:64,185,769...64,253,605
Ensembl chr 9:64,185,770...64,253,631
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA]
CTD PMID:31265865 NCBI chr10:81,105,913...81,124,697
Ensembl chr10:81,105,915...81,133,975
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions
decreases activity
ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased activity of MAP3K5 protein]
Dimethyl Sulfoxide results in decreased activity of MAP3K5 protein
CTD PMID:12370186 NCBI chr10:19,934,101...20,142,750
Ensembl chr10:19,934,472...20,142,753
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 affects expression
increases expression
multiple interactions
ISO Dimethyl Sulfoxide affects the expression of MAPK3 mRNA
Dimethyl Sulfoxide results in increased expression of MAPK3 mRNA
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAPK3 mRNA]
CTD PMID:24834073 PMID:31265865 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mat1a methionine adenosyltransferase I, alpha increases activity EXP Dimethyl Sulfoxide results in increased activity of MAT1A protein CTD PMID:8373829 NCBI chr14:41,105,012...41,124,428
Ensembl chr14:41,105,035...41,124,412
JBrowse link
G Mat2a methionine adenosyltransferase II, alpha increases activity EXP Dimethyl Sulfoxide results in increased activity of MAT2A protein CTD PMID:8373829 NCBI chr 6:72,432,796...72,439,556
Ensembl chr 6:72,432,799...72,439,558
JBrowse link
G Mc1r melanocortin 1 receptor affects expression ISO Dimethyl Sulfoxide affects the expression of MC1R mRNA CTD PMID:24834073 NCBI chr 8:123,407,082...123,410,744
Ensembl chr 8:123,407,107...123,410,744
JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression
decreases expression
ISO Dimethyl Sulfoxide results in increased expression of MEF2C mRNA
Dimethyl Sulfoxide results in decreased expression of MEF2C mRNA
CTD PMID:22105179 NCBI chr13:83,504,017...83,667,079
Ensembl chr13:83,504,034...83,667,080
JBrowse link
G Mettl26 methyltransferase like 26 affects expression ISO Dimethyl Sulfoxide affects the expression of METTL26 mRNA CTD PMID:24834073 NCBI chr17:25,875,500...25,877,163
Ensembl chr17:25,875,074...25,877,169
JBrowse link
G Mfap5 microfibrillar associated protein 5 affects expression ISO Dimethyl Sulfoxide affects the expression of MFAP5 mRNA CTD PMID:24834073 NCBI chr 6:122,513,584...122,529,290
Ensembl chr 6:122,505,845...122,529,290
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) increases expression ISO Dimethyl Sulfoxide results in increased expression of MMP1 mRNA; Dimethyl Sulfoxide results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 protein]
Dimethyl Sulfoxide results in increased expression of MMP2 protein
CTD PMID:26497626 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; Dimethyl Sulfoxide inhibits the reaction [Ethanol results in increased activity of MMP9 protein]
Dimethyl Sulfoxide results in increased expression of MMP9 protein
CTD PMID:17603938 PMID:26497626 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mpo myeloperoxidase increases secretion EXP Dimethyl Sulfoxide results in increased secretion of MPO protein CTD PMID:21633126 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Mrpl43 mitochondrial ribosomal protein L43 affects expression ISO Dimethyl Sulfoxide affects the expression of MRPL43 mRNA CTD PMID:24834073 NCBI chr19:45,005,014...45,006,442
Ensembl chr19:45,004,829...45,006,442
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of MUC5AC protein] CTD PMID:10640773 NCBI chr 7:141,788,958...141,819,227
Ensembl chr 7:141,788,972...141,819,231
JBrowse link
G Mug1 murinoglobulin 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of PZP mRNA; Dimethyl Sulfoxide results in increased expression of PZP protein CTD PMID:14757319 NCBI chr 6:121,838,496...121,889,057
Ensembl chr 6:121,838,541...121,889,057
JBrowse link
G Mxra8 matrix-remodelling associated 8 increases expression ISO Dimethyl Sulfoxide results in increased expression of MXRA8 mRNA CTD PMID:22193206 NCBI chr 4:155,839,680...155,844,102
Ensembl chr 4:155,839,680...155,844,088
JBrowse link
G Myc myelocytomatosis oncogene decreases expression ISO Dimethyl Sulfoxide results in decreased expression of MYC mRNA CTD PMID:7798212 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow multiple interactions
increases phosphorylation
EXP AHR protein affects the reaction [Dimethyl Sulfoxide results in increased phosphorylation of MYL2 protein] CTD PMID:33723743 NCBI chr 5:122,092,724...122,113,473
Ensembl chr 5:122,100,951...122,113,472
JBrowse link
G Myo1g myosin IG increases expression ISO Dimethyl Sulfoxide results in increased expression of MYO1G mRNA CTD PMID:22193206 NCBI chr11:6,506,548...6,520,960
Ensembl chr11:6,506,548...6,520,965
JBrowse link
G Nanog Nanog homeobox decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NANOG mRNA CTD PMID:22105179 NCBI chr 6:122,707,489...122,714,633
Ensembl chr 6:122,707,489...122,714,633
JBrowse link
G Nefh neurofilament, heavy polypeptide decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NEFH mRNA CTD PMID:22105179 NCBI chr11:4,938,754...4,948,064
Ensembl chr11:4,938,754...4,948,064
JBrowse link
G Nes nestin decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NES mRNA CTD PMID:22105179 NCBI chr 3:87,971,093...87,980,451
Ensembl chr 3:87,971,078...87,980,451
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
decreases expression
ISO
EXP
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]
Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]]
Dimethyl Sulfoxide results in decreased expression of NFE2L2 protein
CTD PMID:26497626 PMID:33723743 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA] CTD PMID:21878375 NCBI chr19:46,300,994...46,312,400
Ensembl chr19:46,304,320...46,312,385
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA] CTD PMID:21878375 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nmi N-myc (and STAT) interactor affects expression ISO Dimethyl Sulfoxide affects the expression of NMI mRNA CTD PMID:24834073 NCBI chr 2:51,948,498...51,973,489
Ensembl chr 2:51,948,487...51,973,494
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of NMRK1 mRNA CTD PMID:24834073 NCBI chr19:18,632,016...18,652,428
Ensembl chr19:18,631,950...18,652,428
JBrowse link
G Nos2 nitric oxide synthase 2, inducible decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NOS2 mRNA CTD PMID:21878375 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Notch3 notch 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of NOTCH3 mRNA CTD PMID:20713136 NCBI chr17:32,120,820...32,166,896
Ensembl chr17:32,120,820...32,166,852
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of NQO1 mRNA CTD PMID:22193206 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO DMSO decreases expression of Nr1h4 mRNA and protein in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr10:89,454,234...89,533,645
Ensembl chr10:89,454,234...89,533,585
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions EXP NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] CTD PMID:20371638 NCBI chr 1:171,213,934...171,218,845
Ensembl chr 1:171,213,970...171,220,701
JBrowse link
G Nudt1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 affects expression ISO Dimethyl Sulfoxide affects the expression of NUDT1 mRNA CTD PMID:24834073 NCBI chr 5:140,321,622...140,338,137
Ensembl chr 5:140,321,656...140,338,137
JBrowse link
G Ocln occludin increases expression ISO Dimethyl Sulfoxide results in increased expression of OCLN mRNA CTD PMID:18661270 NCBI chr13:100,496,504...100,552,718
Ensembl chr13:100,496,507...100,552,718
JBrowse link
G Odc1 ornithine decarboxylase, structural 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased activity of ODC1 protein] CTD PMID:7662713 NCBI chr12:17,544,808...17,551,502
Ensembl chr12:17,544,794...17,551,505
JBrowse link
G Orm1 orosomucoid 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of ORM1 mRNA; Dimethyl Sulfoxide results in increased expression of ORM1 protein CTD PMID:14757319 NCBI chr 4:63,344,556...63,348,163
Ensembl chr 4:63,344,560...63,348,163
JBrowse link
G Ostn osteocrin affects expression ISO Dimethyl Sulfoxide affects the expression of OSTN mRNA CTD PMID:24834073 NCBI chr16:27,307,641...27,351,209
Ensembl chr16:27,307,489...27,351,212
JBrowse link
G Padi4 peptidyl arginine deiminase, type IV multiple interactions
increases expression
ISO Calcimycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of PADI4 protein]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of PADI4 mRNA] CTD PMID:15964820 PMID:29425503 NCBI chr 4:140,745,508...140,774,239
Ensembl chr 4:140,745,865...140,774,236
JBrowse link
G Pard6a par-6 family cell polarity regulator alpha affects expression ISO Dimethyl Sulfoxide affects the expression of PARD6A mRNA CTD PMID:24834073 NCBI chr 8:105,701,148...105,703,494
Ensembl chr 8:105,701,148...105,703,496
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage EXP Dimethyl Sulfoxide results in increased cleavage of PARP1 protein CTD PMID:22535522 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO Dimethyl Sulfoxide results in increased expression of PDCD4 protein CTD PMID:17259349 NCBI chr19:53,892,231...53,937,592
Ensembl chr19:53,892,231...53,929,860
JBrowse link
G Phf6 PHD finger protein 6 affects expression ISO Dimethyl Sulfoxide affects the expression of PHF6 mRNA CTD PMID:24834073 NCBI chr  X:52,912,214...52,956,961
Ensembl chr  X:52,912,266...52,956,943
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE type zinc finger containing affects expression ISO Dimethyl Sulfoxide affects the expression of PIKFYVE mRNA CTD PMID:24834073 NCBI chr 1:65,186,640...65,278,696
Ensembl chr 1:65,186,683...65,278,695
JBrowse link
G Pjvk pejvakin affects expression ISO Dimethyl Sulfoxide affects the expression of PJVK mRNA CTD PMID:24834073 NCBI chr 2:76,650,273...76,658,554
Ensembl chr 2:76,648,476...76,658,556
JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PLA2G2A mRNA CTD PMID:21878375 NCBI chr 4:138,831,857...138,835,189
Ensembl chr 4:138,831,857...138,835,186
JBrowse link
G Plekhf1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 affects expression ISO Dimethyl Sulfoxide affects the expression of PLEKHF1 mRNA CTD PMID:24834073 NCBI chr 7:38,220,654...38,227,994
Ensembl chr 7:38,216,972...38,228,016
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of PLOD2 mRNA CTD PMID:22193206 NCBI chr 9:92,539,636...92,608,428
Ensembl chr 9:92,542,223...92,608,428
JBrowse link
G Pomc pro-opiomelanocortin-alpha decreases expression EXP Dimethyl Sulfoxide results in decreased expression of POMC protein CTD PMID:15680486 NCBI chr12:3,954,945...3,960,643
Ensembl chr12:3,954,951...3,960,642
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
decreases activity
EXP
ISO
Dimethyl Sulfoxide inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical]
Dimethyl Sulfoxide results in decreased activity of POR protein
Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Dimethyl Sulfoxide promotes the reaction [Hemin results in decreased activity of POR protein]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide results in decreased activity of POR protein]
CTD PMID:11368792 PMID:21215309 NCBI chr 5:135,670,040...135,735,326
Ensembl chr 5:135,670,033...135,735,326
JBrowse link
G Pot1a protection of telomeres 1A multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; [Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA CTD PMID:26330309 NCBI chr 6:25,743,940...25,809,277
Ensembl chr 6:25,743,737...25,809,246
JBrowse link
G Pou5f1 POU domain, class 5, transcription factor 1 affects expression ISO Dimethyl Sulfoxide affects the expression of POU5F1 mRNA CTD PMID:24834073 NCBI chr17:35,506,032...35,510,777
Ensembl chr17:35,506,018...35,510,772
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PPARA mRNA CTD PMID:21878375 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PPARG mRNA CTD PMID:21878375 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Pqbp1 polyglutamine binding protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of PQBP1 mRNA CTD PMID:24834073 NCBI chr  X:7,894,519...7,899,269
Ensembl chr  X:7,894,519...7,899,269
JBrowse link
G Prmt1 protein arginine N-methyltransferase 1 multiple interactions ISO PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]] CTD PMID:31877331 NCBI chr 7:44,976,755...44,986,420
Ensembl chr 7:44,975,989...44,986,568
JBrowse link
G Prph peripherin affects expression ISO Dimethyl Sulfoxide affects the expression of PRPH mRNA CTD PMID:24834073 NCBI chr15:99,053,579...99,058,978
Ensembl chr15:99,055,174...99,058,978
JBrowse link
G Ptgds prostaglandin D2 synthase (brain) multiple interactions EXP [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGDS mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGDS mRNA] CTD PMID:23751068 NCBI chr 2:25,466,709...25,470,110
Ensembl chr 2:25,466,709...25,470,046
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PTGS1 mRNA CTD PMID:21878375 NCBI chr 2:36,216,742...36,258,593
Ensembl chr 2:36,230,426...36,252,272
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Dimethyl Sulfoxide results in increased expression of PTGS2 protein
[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein]
CTD PMID:21878375 PMID:23751068 PMID:26497626 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Pxdn peroxidasin increases expression ISO Dimethyl Sulfoxide results in increased expression of PXDN mRNA CTD PMID:22193206 NCBI chr12:29,936,642...30,017,658
Ensembl chr12:29,937,608...30,017,658
JBrowse link
G Rab3c RAB3C, member RAS oncogene family affects expression ISO Dimethyl Sulfoxide affects the expression of RAB3C mRNA CTD PMID:24834073 NCBI chr13:110,054,187...110,280,996
Ensembl chr13:110,054,187...110,280,996
JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 multiple interactions ISO [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of RAF1 mRNA CTD PMID:31265865 NCBI chr 6:115,618,569...115,676,635
Ensembl chr 6:115,618,067...115,676,635
JBrowse link
G Reln reelin increases expression ISO Dimethyl Sulfoxide results in increased expression of RELN mRNA CTD PMID:17065238 NCBI chr 5:21,884,454...22,344,705
Ensembl chr 5:21,884,454...22,344,702
JBrowse link
G Rfx3 regulatory factor X, 3 (influences HLA class II expression) affects expression ISO Dimethyl Sulfoxide affects the expression of RFX3 mRNA CTD PMID:24834073 NCBI chr19:27,761,721...28,014,669
Ensembl chr19:27,761,721...28,011,166
JBrowse link
G Rnase4 ribonuclease, RNase A family 4 affects expression ISO Dimethyl Sulfoxide affects the expression of RNASE4 mRNA CTD PMID:24834073 NCBI chr14:51,091,077...51,106,151
Ensembl chr14:51,091,077...51,106,151
JBrowse link
G Rnf152 ring finger protein 152 affects expression ISO Dimethyl Sulfoxide affects the expression of RNF152 mRNA CTD PMID:24834073 NCBI chr 1:105,276,917...105,356,991
Ensembl chr 1:105,276,914...105,356,710
JBrowse link
G Rxra retinoid X receptor alpha increases expression
affects response to substance
EXP Dimethyl Sulfoxide results in increased expression of RXRA mRNA; Dimethyl Sulfoxide results in increased expression of RXRA protein
RXRA protein affects the susceptibility to Dimethyl Sulfoxide
CTD PMID:9751115 NCBI chr 2:27,676,445...27,763,319
Ensembl chr 2:27,676,440...27,762,957
JBrowse link
G Rxrg retinoid X receptor gamma decreases expression EXP Dimethyl Sulfoxide results in decreased expression of RXRG protein CTD PMID:9751115 NCBI chr 1:167,598,362...167,639,623
Ensembl chr 1:167,598,384...167,639,623
JBrowse link
G S100a13 S100 calcium binding protein A13 affects expression ISO Dimethyl Sulfoxide affects the expression of S100A13 mRNA CTD PMID:24834073 NCBI chr 3:90,514,233...90,524,581
Ensembl chr 3:90,514,435...90,524,581
JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) increases expression ISO Dimethyl Sulfoxide results in increased expression of S100A8 mRNA CTD PMID:1733233 NCBI chr 3:90,669,071...90,670,034
Ensembl chr 3:90,668,978...90,670,035
JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) increases expression ISO Dimethyl Sulfoxide results in increased expression of S100A9 mRNA CTD PMID:1733233 NCBI chr 3:90,692,630...90,695,721
Ensembl chr 3:90,692,632...90,695,721
JBrowse link
G Sdhaf4 succinate dehydrogenase complex assembly factor 4 affects expression ISO Dimethyl Sulfoxide affects the expression of SDHAF4 mRNA CTD PMID:24834073 NCBI chr 1:23,995,939...24,005,640
Ensembl chr 1:23,995,939...24,005,656
JBrowse link
G Selenbp2 selenium binding protein 2 increases abundance ISO SELENBP1 gene mutant form results in increased abundance of Dimethyl Sulfoxide CTD PMID:29255262 NCBI chr 3:94,693,573...94,704,406
Ensembl chr 3:94,693,556...94,704,413
JBrowse link
G Serp2 stress-associated endoplasmic reticulum protein family member 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SERP2 mRNA CTD PMID:24834073 NCBI chr14:76,532,812...76,557,074
Ensembl chr14:76,532,814...76,556,889
JBrowse link
G Slc24a2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of SLC24A2 mRNA CTD PMID:22193206 NCBI chr 4:86,983,124...87,230,652
Ensembl chr 4:86,983,124...87,230,477
JBrowse link
G Slc24a4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 increases expression ISO Dimethyl Sulfoxide results in increased expression of SLC24A4 mRNA CTD PMID:22193206 NCBI chr12:102,128,727...102,267,133
Ensembl chr12:102,128,733...102,267,091
JBrowse link
G Slc2a6 solute carrier family 2 (facilitated glucose transporter), member 6 affects expression ISO Dimethyl Sulfoxide affects the expression of SLC2A6 mRNA CTD PMID:24834073 NCBI chr 2:27,021,363...27,028,000
Ensembl chr 2:27,021,363...27,027,998
JBrowse link
G Slc35e4 solute carrier family 35, member E4 affects expression ISO Dimethyl Sulfoxide affects the expression of SLC35E4 mRNA CTD PMID:24834073 NCBI chr11:3,907,022...3,914,664
Ensembl chr11:3,907,021...3,914,664
JBrowse link
G Snx15 sorting nexin 15 affects expression ISO Dimethyl Sulfoxide affects the expression of SNX15 mRNA CTD PMID:24834073 NCBI chr19:6,119,399...6,132,415
Ensembl chr19:6,119,399...6,128,304
JBrowse link
G Sod3 superoxide dismutase 3, extracellular increases expression ISO Dimethyl Sulfoxide results in increased expression of SOD3 mRNA CTD PMID:22193206 NCBI chr 5:52,363,804...52,369,738
Ensembl chr 5:52,363,791...52,371,418
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Carbon Tetrachloride results in increased activity of SORD protein] CTD PMID:17177172 NCBI chr 2:122,234,839...122,265,337
Ensembl chr 2:122,234,749...122,265,340
JBrowse link
G Sox17 SRY (sex determining region Y)-box 17 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of SOX17 mRNA CTD PMID:22105179 NCBI chr 1:4,490,928...4,497,426
Ensembl chr 1:4,490,931...4,497,354
JBrowse link
G Sp1 trans-acting transcription factor 1 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr15:102,406,316...102,436,404
Ensembl chr15:102,406,143...102,436,404
JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SPINK2 mRNA CTD PMID:24834073 NCBI chr 5:77,205,106...77,216,258
Ensembl chr 5:77,205,107...77,211,471
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO DMSO increases expression of Srebf1 mRNA in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr11:60,199,084...60,224,186
Ensembl chr11:60,199,089...60,222,581
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) increases expression ISO Dimethyl Sulfoxide results in increased expression of SRXN1 mRNA CTD PMID:22193206 NCBI chr 2:152,105,524...152,111,376
Ensembl chr 2:152,105,516...152,111,376
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 affects expression ISO Dimethyl Sulfoxide affects the expression of STAC3 mRNA CTD PMID:24834073 NCBI chr10:127,501,617...127,508,823
Ensembl chr10:127,501,686...127,508,823
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of STAT3 mRNA CTD PMID:31265865 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects expression ISO Dimethyl Sulfoxide affects the expression of SUMO1 mRNA CTD PMID:24834073 NCBI chr 1:59,639,434...59,670,834
Ensembl chr 1:59,586,558...59,670,834
JBrowse link
G Syce2 synaptonemal complex central element protein 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SYCE2 mRNA CTD PMID:24834073 NCBI chr 8:84,872,111...84,887,446
Ensembl chr 8:84,872,111...84,888,221
JBrowse link
G Tas2r140 taste receptor, type 2, member 140 affects expression ISO Dimethyl Sulfoxide affects the expression of TAS2R14 mRNA CTD PMID:24834073 NCBI chr 6:133,054,855...133,055,793
Ensembl chr 6:133,054,817...133,055,816
JBrowse link
G Tatdn1 TatD DNase domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of TATDN1 mRNA CTD PMID:24834073 NCBI chr15:58,890,153...58,933,756
Ensembl chr15:58,890,155...58,933,738
JBrowse link
G Terc telomerase RNA component multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA CTD PMID:26330309 NCBI chr 3:96,414,437...96,414,833
Ensembl chr 3:96,414,437...96,414,859
Ensembl chr 3:96,414,437...96,414,859
JBrowse link
G Terf1 telomeric repeat binding factor 1 multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA CTD PMID:26330309 NCBI chr 1:15,805,546...15,844,052
Ensembl chr 1:15,805,646...15,844,052
JBrowse link
G Terf2 telomeric repeat binding factor 2 multiple interactions ISO [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dimethyl Sulfoxide co-treated with Tretinoin] results in decreased expression of TERF2 mRNA; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF2 mRNA CTD PMID:26330309 NCBI chr 8:107,069,400...107,096,548
Ensembl chr 8:107,069,400...107,096,547
JBrowse link
G Tert telomerase reverse transcriptase decreases expression
multiple interactions
EXP
ISO
Dimethyl Sulfoxide results in decreased expression of TERT mRNA
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA
CTD PMID:16180984 PMID:26330309 NCBI chr13:73,626,911...73,649,843
Ensembl chr13:73,626,911...73,649,843
JBrowse link
G Tfpi tissue factor pathway inhibitor affects expression ISO Dimethyl Sulfoxide affects the expression of TFPI mRNA CTD PMID:24834073 NCBI chr 2:84,432,855...84,476,775
Ensembl chr 2:84,432,855...84,476,775
JBrowse link
G Tgm2 transglutaminase 2, C polypeptide multiple interactions ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4-16 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]] CTD PMID:15964820 NCBI chr 2:158,116,405...158,146,392
Ensembl chr 2:158,116,402...158,146,436
JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of TIMP2 protein] CTD PMID:11682029 NCBI chr11:118,301,061...118,355,411
Ensembl chr11:118,301,069...118,355,740
JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein affects expression ISO Dimethyl Sulfoxide affects the expression of TIRAP mRNA CTD PMID:24834073 NCBI chr 9:35,184,391...35,200,291
Ensembl chr 9:35,184,551...35,200,291
JBrowse link
G Tjp1 tight junction protein 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of TJP1 mRNA CTD PMID:18661270 NCBI chr 7:65,296,165...65,527,850
Ensembl chr 7:65,296,165...65,527,781
JBrowse link
G Tmem121 transmembrane protein 121 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM121 mRNA CTD PMID:24834073 NCBI chr12:113,185,903...113,189,523
Ensembl chr12:113,185,930...113,189,523
JBrowse link
G Tmem134 transmembrane protein 134 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM134 mRNA CTD PMID:24834073 NCBI chr19:4,125,960...4,132,307
Ensembl chr19:4,125,934...4,132,307
JBrowse link
G Tmem150c transmembrane protein 150C affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM150C mRNA CTD PMID:24834073 NCBI chr 5:100,077,872...100,165,607
Ensembl chr 5:100,077,872...100,159,808
JBrowse link
G Tmem266 transmembrane protein 266 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM266 mRNA CTD PMID:24834073 NCBI chr 9:55,326,913...55,438,345
Ensembl chr 9:55,326,913...55,438,345
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [ferrous sulfate promotes the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]]
Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Ethanol promotes the reaction [Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]
CTD PMID:7539275 PMID:14576080 PMID:21878375 PMID:22319556 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a increases expression ISO Dimethyl Sulfoxide results in increased expression of TNFRSF12A mRNA CTD PMID:22193206 NCBI chr17:23,675,445...23,677,449
Ensembl chr17:23,675,445...23,677,468
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]; Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein] CTD PMID:9870925 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Tomm5 translocase of outer mitochondrial membrane 5 affects expression ISO Dimethyl Sulfoxide affects the expression of TOMM5 mRNA CTD PMID:24834073 NCBI chr 4:45,105,209...45,108,113
Ensembl chr 4:45,105,208...45,108,114
JBrowse link
G Tpm3 tropomyosin 3, gamma increases expression ISO Dimethyl Sulfoxide results in increased expression of TPM3 mRNA CTD PMID:22193206 NCBI chr 3:90,072,651...90,100,902
Ensembl chr 3:90,072,649...90,100,902
JBrowse link
G Tra2b transformer 2 beta increases expression ISO Dimethyl Sulfoxide results in increased expression of TRA2B mRNA CTD PMID:22193206 NCBI chr16:22,244,552...22,266,005
Ensembl chr16:22,244,549...22,266,005
JBrowse link
G Trf transferrin increases expression ISO Dimethyl Sulfoxide results in increased expression of TF mRNA CTD PMID:22193206 NCBI chr 9:103,208,876...103,230,286
Ensembl chr 9:103,204,001...103,230,444
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of TRIB3 mRNA CTD PMID:22193206 NCBI chr 2:152,337,425...152,344,060
Ensembl chr 2:152,337,422...152,344,032
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 affects expression ISO Dimethyl Sulfoxide affects the expression of TSC22D3 mRNA CTD PMID:24834073 NCBI chr  X:140,539,528...140,600,522
Ensembl chr  X:140,539,528...140,600,659
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression ISO Dimethyl Sulfoxide results in decreased expression of TUBB3 mRNA CTD PMID:22105179 NCBI chr 8:123,411,553...123,422,015
Ensembl chr 8:123,411,424...123,422,015
JBrowse link
G U2af1l4 U2 small nuclear RNA auxiliary factor 1-like 4 affects expression ISO Dimethyl Sulfoxide affects the expression of U2AF1L4 mRNA CTD PMID:24834073 NCBI chr 7:30,563,340...30,565,364
Ensembl chr 7:30,563,301...30,565,365
Ensembl chr 7:30,563,301...30,565,365
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C affects expression ISO Dimethyl Sulfoxide affects the expression of UBE2C mRNA CTD PMID:24834073 NCBI chr 2:164,769,929...164,772,902
Ensembl chr 2:164,769,898...164,778,822
JBrowse link
G Ufsp1 UFM1-specific peptidase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of UFSP1 mRNA CTD PMID:24834073 NCBI chr 5:137,294,669...137,295,664
Ensembl chr 5:137,294,629...137,295,665
JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B affects expression ISO Dimethyl Sulfoxide affects the expression of UGT1A6 mRNA CTD PMID:12843640 NCBI chr 1:88,103,257...88,218,998
Ensembl chr 1:88,103,252...88,219,003
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 affects expression ISO Dimethyl Sulfoxide affects the expression of UGT1A9 mRNA CTD PMID:12843640 NCBI chr 1:88,070,779...88,220,002
Ensembl chr 1:88,070,800...88,218,997
JBrowse link
G Upk3b uroplakin 3B affects expression ISO Dimethyl Sulfoxide affects the expression of UPK3B mRNA CTD PMID:24834073 NCBI chr 5:136,038,496...136,044,993
Ensembl chr 5:136,038,496...136,046,487
JBrowse link
G Uts2r urotensin 2 receptor affects expression ISO Dimethyl Sulfoxide affects the expression of UTS2R mRNA CTD PMID:24834073 NCBI chr11:121,160,271...121,161,973
Ensembl chr11:121,160,271...121,161,973
JBrowse link
G Vmn1r224 vomeronasal 1 receptor 224 affects expression ISO Dimethyl Sulfoxide affects the expression of VN1R2 mRNA CTD PMID:24834073 NCBI chr17:20,419,163...20,420,059
Ensembl chr17:20,414,146...20,425,343
JBrowse link
G Wapl WAPL cohesin release factor increases expression ISO Dimethyl Sulfoxide results in increased expression of WAPL mRNA CTD PMID:15797623 NCBI chr14:34,672,379...34,747,983
Ensembl chr14:34,673,928...34,747,983
JBrowse link
G Wnt11 wingless-type MMTV integration site family, member 11 affects expression ISO Dimethyl Sulfoxide affects the expression of WNT11 mRNA CTD PMID:24834073 NCBI chr 7:98,835,084...98,854,747
Ensembl chr 7:98,835,112...98,855,195
JBrowse link
G Zfp36 zinc finger protein 36 affects expression ISO Dimethyl Sulfoxide affects the expression of ZFP36 mRNA CTD PMID:24834073 NCBI chr 7:28,376,784...28,379,228
Ensembl chr 7:28,376,784...28,380,253
JBrowse link
edrophonium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO Edrophonium binds to and results in decreased activity of ACHE protein; Edrophonium inhibits the reaction [asoxime chloride inhibits the reaction [cyclohexyl methylphosphonofluoridate results in decreased activity of ACHE protein]]; Edrophonium inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Edrophonium inhibits the reaction [Obidoxime Chloride metabolite results in decreased activity of ACHE protein]; Edrophonium promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]
Edrophonium results in decreased activity of ACHE protein
CTD PMID:25522658 PMID:27297626 NCBI chr 5:137,288,247...137,294,466
Ensembl chr 5:137,287,519...137,294,466
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO Edrophonium binds to and results in decreased activity of BCHE protein CTD PMID:31173753 NCBI chr 3:73,635,805...73,708,436
Ensembl chr 3:73,635,808...73,708,415
JBrowse link
ferric ammonium citrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 increases activity
decreases activity
EXP ferric ammonium citrate results in increased activity of ACO1 protein
ferric ammonium citrate results in decreased activity of ACO1 protein
CTD PMID:11054110 PMID:18073202 NCBI chr 4:40,143,265...40,199,009
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Aco2 aconitase 2, mitochondrial multiple interactions
increases activity
ISO ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]; ferric ammonium citrate inhibits the reaction [Manganese results in decreased activity of ACO2 protein]
ferric ammonium citrate results in increased activity of ACO2 protein
CTD PMID:16625280 NCBI chr15:81,872,463...81,915,137
Ensembl chr15:81,872,309...81,915,133
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] CTD PMID:32283200 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Alb albumin multiple interactions EXP ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of ALB protein] CTD PMID:24862973 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Anxa3 annexin A3 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ANXA3 protein] CTD PMID:19515424 NCBI chr 5:96,793,385...96,845,968
Ensembl chr 5:96,793,339...96,845,966
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor (GDI) alpha multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ARHGDIA protein] CTD PMID:19515424 NCBI chr11:120,578,099...120,581,624
Ensembl chr11:120,578,104...120,581,624
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr13:38,345,716...38,500,314
Ensembl chr13:38,345,107...38,500,302
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO
EXP
ferric ammonium citrate results in increased cleavage of CASP3 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
CTD PMID:17191120 PMID:26318285 PMID:27481217 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions ISO ferric ammonium citrate inhibits the reaction [2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein] CTD PMID:12807743 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Col1a1 collagen, type I, alpha 1 decreases expression EXP ferric ammonium citrate results in decreased expression of COL1A1 mRNA CTD PMID:19735707 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of CXCL8 mRNA]; ferric ammonium citrate inhibits the reaction [Ozone results in increased secretion of CXCL8 protein] CTD PMID:24862973 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases phosphorylation
EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Cyclosporine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; ferric ammonium citrate results in decreased phosphorylation of and affects the localization of DNM1L protein; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] CTD PMID:26318285 PMID:27481217 NCBI chr16:16,312,228...16,359,038
Ensembl chr16:16,312,230...16,358,959
JBrowse link
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 NCBI chr11:106,397,620...106,487,796
Ensembl chr11:106,394,650...106,487,852
JBrowse link
G Erp29 endoplasmic reticulum protein 29 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ERP29 protein] CTD PMID:19515424 NCBI chr 5:121,444,753...121,452,474
Ensembl chr 5:121,428,590...121,452,506
JBrowse link
G F3 coagulation factor III increases expression
multiple interactions
ISO ferric ammonium citrate results in increased expression of F3 mRNA
Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased expression of F3 mRNA]
CTD PMID:25858758 NCBI chr 3:121,723,537...121,735,052
Ensembl chr 3:121,723,537...121,735,048
JBrowse link
G Fth1 ferritin heavy polypeptide 1 multiple interactions ISO ferric ammonium citrate promotes the reaction [Palmitic Acid results in increased expression of FTH1 protein] CTD PMID:32283200 NCBI chr19:9,980,600...9,985,111
Ensembl chr19:9,980,598...9,985,098
JBrowse link
G Ftl1 ferritin light polypeptide 1 multiple interactions
increases expression
ISO
EXP
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of FTL mRNA
SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA]
CTD PMID:12393473 PMID:19913091 NCBI chr 7:45,457,944...45,459,886
Ensembl chr 7:45,457,944...45,459,884
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein] CTD PMID:19515424 NCBI chr 6:125,161,852...125,166,467
Ensembl chr 6:125,161,715...125,166,467
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GLO1 protein] CTD PMID:19515424 NCBI chr17:30,592,861...30,612,659
Ensembl chr17:30,584,936...30,626,871
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
ISO Deferoxamine promotes the reaction [ferric ammonium citrate results in decreased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 7:30,942,368...30,944,029
Ensembl chr 7:30,942,368...30,944,032
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO ferric ammonium citrate results in increased expression of HMOX1 protein
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HMOX1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ferric ammonium citrate results in increased expression of HMOX1 protein]
CTD PMID:12393473 PMID:16439612 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hspa1a heat shock protein 1A multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPA1A protein] CTD PMID:19515424 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Hspa1l heat shock protein 1-like multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA1L mRNA CTD PMID:12393473 NCBI chr17:34,972,703...34,979,228
Ensembl chr17:34,972,703...34,979,285
JBrowse link
G Hspa9 heat shock protein 9 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA9 mRNA CTD PMID:12393473 NCBI chr18:34,937,414...34,954,351
Ensembl chr18:34,937,414...34,954,357
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPD1 protein] CTD PMID:19515424 NCBI chr 1:55,077,833...55,088,243
Ensembl chr 1:55,077,835...55,088,243
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL1B protein] CTD PMID:24862973 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL6 mRNA]; ferric ammonium citrate inhibits the reaction [Ozone results in increased secretion of IL6 protein] CTD PMID:24862973 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Ins2 insulin II multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Thapsigargin inhibits the reaction [ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]] CTD PMID:32283200 NCBI chr 7:142,678,656...142,679,726
Ensembl chr 7:142,678,656...142,743,381
JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases expression
decreases activity
ISO
EXP
ferric ammonium citrate results in decreased expression of IREB2 protein
ferric ammonium citrate results in decreased activity of IREB2 protein
CTD PMID:11054110 PMID:17469137 PMID:18073202 NCBI chr 9:54,862,658...54,912,534
Ensembl chr 9:54,863,789...54,912,530
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP ferric ammonium citrate inhibits the reaction [bathophenanthroline disulfonic acid results in decreased expression of LCN2 protein] CTD PMID:17350462 NCBI chr 2:32,384,637...32,387,739
Ensembl chr 2:32,384,633...32,388,252
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK1 protein
ferric ammonium citrate results in increased phosphorylation of MAPK1 protein
CTD PMID:17191120 PMID:25858758 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 increases phosphorylation ISO ferric ammonium citrate results in increased phosphorylation of MAPK14 protein CTD PMID:17191120 NCBI chr17:28,691,342...28,748,405
Ensembl chr17:28,691,329...28,748,406
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK3 protein
ferric ammonium citrate results in increased phosphorylation of MAPK3 protein
CTD PMID:17191120 PMID:25858758 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of MRPS9 protein] CTD PMID:19515424 NCBI chr 1:42,851,233...42,905,683
Ensembl chr 1:42,851,233...42,905,683
JBrowse link
G Mt2 metallothionein 2 multiple interactions ISO [ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of MT2A mRNA CTD PMID:12393473 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of NCOA4 protein] CTD PMID:32283200 NCBI chr14:32,159,879...32,179,855
Ensembl chr14:32,159,865...32,179,855
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA; Acetylcysteine inhibits the reaction [[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA] CTD PMID:9826428 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Oga O-GlcNAcase multiple interactions EXP ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of OGA protein] CTD PMID:24862973 NCBI chr19:45,750,255...45,783,644
Ensembl chr19:45,750,259...45,783,837
JBrowse link
G P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of P4HA1 protein] CTD PMID:19515424 NCBI chr10:59,323,197...59,373,304
Ensembl chr10:59,323,296...59,373,304
JBrowse link
G Pdhb pyruvate dehydrogenase (lipoamide) beta multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PDHB protein] CTD PMID:19515424 NCBI chr14:8,165,991...8,173,303
Ensembl chr14:8,165,996...8,173,025
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PGK1 protein] CTD PMID:19515424 NCBI chr  X:106,187,100...106,203,699
Ensembl chr  X:106,187,100...106,203,699
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of PMP22 mRNA CTD PMID:12393473 NCBI chr11:63,128,982...63,159,547
Ensembl chr11:63,128,982...63,159,547
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PPIA protein] CTD PMID:19515424 NCBI chr11:6,415,867...6,419,817
Ensembl chr11:6,415,443...6,419,817
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of PTGS2 mRNA] CTD PMID:24862973 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Rack1 receptor for activated C kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of RACK1 protein] CTD PMID:19515424 NCBI chr11:48,800,360...48,806,241
Ensembl chr11:48,800,332...48,806,434
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 increases expression EXP ferric ammonium citrate results in increased expression of SLC11A1 mRNA CTD PMID:11054110 NCBI chr 1:74,375,014...74,386,057
Ensembl chr 1:74,375,195...74,386,062
JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 increases expression EXP ferric ammonium citrate results in increased expression of SLC11A2 mRNA CTD PMID:11054110 NCBI chr15:100,387,898...100,424,209
Ensembl chr15:100,387,898...100,425,072
JBrowse link
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 increases expression
multiple interactions
EXP
ISO
ferric ammonium citrate results in increased expression of SLC40A1 mRNA
SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA]
CTD PMID:19913091 NCBI chr 1:45,908,070...45,926,532
Ensembl chr 1:45,908,068...45,926,523
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of SOD1 mRNA] CTD PMID:24862973 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Tfr2 transferrin receptor 2 decreases expression ISO ferric ammonium citrate results in decreased expression of TFR2 protein CTD PMID:25633564 NCBI chr 5:137,569,822...137,588,081
Ensembl chr 5:137,569,840...137,587,481
JBrowse link
G Tfrc transferrin receptor decreases expression
multiple interactions
ISO
EXP
ferric ammonium citrate results in decreased expression of TFRC mRNA; ferric ammonium citrate results in decreased expression of TFRC protein
[ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of TFRC mRNA
CTD PMID:11054110 PMID:12393473 PMID:16760464 PMID:18073202 PMID:25633564 NCBI chr16:32,608,896...32,632,794
Ensembl chr16:32,608,920...32,632,794
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of TNF protein] CTD PMID:24862973 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tpd52l1 tumor protein D52-like 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of TPD52L1 protein] CTD PMID:19515424 NCBI chr10:31,332,373...31,445,987
Ensembl chr10:31,332,376...31,445,958
JBrowse link
G Trf transferrin multiple interactions ISO ferric ammonium citrate inhibits the reaction [TF protein results in increased uptake of Iron] CTD PMID:11335103 NCBI chr 9:103,208,876...103,230,286
Ensembl chr 9:103,204,001...103,230,444
JBrowse link
G Vdac2 voltage-dependent anion channel 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of VDAC2 protein] CTD PMID:19515424 NCBI chr14:21,831,561...21,845,879
Ensembl chr14:21,825,238...21,845,879
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of XBP1 protein] CTD PMID:32283200 NCBI chr11:5,520,641...5,525,993
Ensembl chr11:5,520,659...5,525,893
JBrowse link
fluorescein (lactone form) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions ISO [CYP2C19 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein; Tranylcypromine inhibits the reaction [[CYP2C19 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein] CTD PMID:23850985 NCBI chr19:39,389,556...39,463,103
Ensembl chr19:39,389,556...39,463,075
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 multiple interactions ISO [CYP2C9 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein; Sulfaphenazole inhibits the reaction [[CYP2C9 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein] CTD PMID:23850985 NCBI chr19:39,061,006...39,093,948
Ensembl chr19:39,061,015...39,093,944
JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 multiple interactions ISO [CYP2C9 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein; Sulfaphenazole inhibits the reaction [[CYP2C9 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein] CTD PMID:23850985 NCBI chr19:39,113,898...39,186,756
Ensembl chr19:39,113,898...39,187,072
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Fluorescein results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,319,589...24,351,684
Ensembl chr 5:24,319,589...24,351,604
JBrowse link
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 multiple interactions ISO Fluorescein inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:11602689 NCBI chr19:8,617,996...8,628,299
Ensembl chr19:8,618,039...8,628,299
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions
increases uptake
ISO bisphenol A inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein]; bisphenol F promotes the reaction [SLCO1B3 protein results in increased uptake of Fluorescein]; Probenecid inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein]; tetrabromobisphenol A inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein] CTD PMID:27989701 NCBI chr 6:141,629,452...141,686,646
Ensembl chr 6:141,629,518...141,686,646
JBrowse link
G Slco3a1 solute carrier organic anion transporter family, member 3a1 increases uptake
multiple interactions
ISO SLCO3A1 protein results in increased uptake of Fluorescein
Cyclosporine promotes the reaction [SLCO3A1 protein results in increased uptake of Fluorescein]; simvastatin acid affects the reaction [SLCO3A1 protein results in increased uptake of Fluorescein]
CTD PMID:28887287 NCBI chr 7:74,275,418...74,554,780
Ensembl chr 7:74,275,419...74,554,780
JBrowse link
fluorescein 5-isothiocyanate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 affects binding ISO Fluorescein-5-isothiocyanate binds to ABCB7 protein CTD PMID:27129696 NCBI chr  X:104,280,565...104,413,846
Ensembl chr  X:104,280,657...104,413,856
JBrowse link
G Akr1c21 aldo-keto reductase family 1, member C21 increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr13:4,574,075...4,586,543
Ensembl chr13:4,574,075...4,586,541
JBrowse link
G Anxa4 annexin A4 affects binding ISO Fluorescein-5-isothiocyanate binds to ANXA4 protein CTD PMID:27129696 NCBI chr 6:86,736,840...86,793,634
Ensembl chr 6:86,736,840...86,793,584
JBrowse link
G Arhgap6 Rho GTPase activating protein 6 affects binding ISO Fluorescein-5-isothiocyanate binds to ARHGAP6 protein CTD PMID:27129696 NCBI chr  X:168,795,094...169,304,440
Ensembl chr  X:168,795,099...169,304,435
JBrowse link
G Azi2 5-azacytidine induced gene 2 affects binding ISO Fluorescein-5-isothiocyanate binds to AZI2 protein CTD PMID:27129696 NCBI chr 9:118,040,442...118,069,798
Ensembl chr 9:118,040,499...118,069,794
JBrowse link
G Capzb capping protein (actin filament) muscle Z-line, beta affects binding ISO Fluorescein-5-isothiocyanate binds to CAPZB protein CTD PMID:27129696 NCBI chr 4:139,192,899...139,291,820
Ensembl chr 4:139,192,899...139,291,818
JBrowse link
G Cd109 CD109 antigen affects binding ISO Fluorescein-5-isothiocyanate binds to CD109 protein CTD PMID:27129696 NCBI chr 9:78,615,546...78,716,260
Ensembl chr 9:78,615,546...78,716,253
JBrowse link
G Cd180 CD180 antigen affects binding ISO Fluorescein-5-isothiocyanate binds to CD180 protein CTD PMID:27129696 NCBI chr13:102,693,547...102,706,631
Ensembl chr13:102,693,558...102,739,629
JBrowse link
G Cd86 CD86 antigen increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr16:36,568,956...36,666,158
Ensembl chr16:36,603,869...36,666,081
JBrowse link
G Cd93 CD93 antigen affects binding ISO Fluorescein-5-isothiocyanate binds to CD93 protein CTD PMID:27129696 NCBI chr 2:148,436,651...148,443,535
Ensembl chr 2:148,436,640...148,443,563
JBrowse link
G Cdc20 cell division cycle 20 affects binding ISO Fluorescein-5-isothiocyanate binds to CDC20 protein CTD PMID:27129696 NCBI chr 4:118,432,901...118,437,343
Ensembl chr 4:118,432,901...118,437,352
JBrowse link
G Copa coatomer protein complex subunit alpha affects binding ISO Fluorescein-5-isothiocyanate binds to COPA protein CTD PMID:27129696 NCBI chr 1:172,082,529...172,122,332
Ensembl chr 1:172,082,529...172,122,330
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of CYP1A1 mRNA CTD PMID:20491607 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Dcaf4 DDB1 and CUL4 associated factor 4 affects binding ISO Fluorescein-5-isothiocyanate binds to DCAF4 protein CTD PMID:27129696 NCBI chr12:83,520,447...83,541,994
Ensembl chr12:83,520,466...83,541,920
JBrowse link
G Dot1l DOT1-like, histone H3 methyltransferase (S. cerevisiae) affects binding ISO Fluorescein-5-isothiocyanate binds to DOT1L protein CTD PMID:27129696 NCBI chr10:80,755,101...80,795,461
Ensembl chr10:80,755,206...80,795,461
JBrowse link
G Elac1 elaC ribonuclease Z 1 affects binding ISO Fluorescein-5-isothiocyanate binds to ELAC1 protein CTD PMID:27129696 NCBI chr18:73,735,038...73,754,519
Ensembl chr18:73,735,038...73,754,479
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 affects binding ISO Fluorescein-5-isothiocyanate binds to ENPP7 protein CTD PMID:27129696 NCBI chr11:118,988,181...118,993,221
Ensembl chr11:118,988,188...118,993,221
JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 affects binding ISO Fluorescein-5-isothiocyanate binds to FLRT3 protein CTD PMID:27129696 NCBI chr 2:140,658,198...140,671,476
Ensembl chr 2:140,650,914...140,671,469
JBrowse link
G Fn1 fibronectin 1 affects binding ISO Fluorescein-5-isothiocyanate binds to FN1 protein CTD PMID:27129696 NCBI chr 1:71,585,473...71,653,280
Ensembl chr 1:71,585,520...71,653,200
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP [Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of HMOX1 protein
Fluorescein-5-isothiocyanate results in increased expression of HMOX1 protein
CTD PMID:27871981 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hspa5 heat shock protein 5 affects binding ISO Fluorescein-5-isothiocyanate binds to HSPA5 protein CTD PMID:27129696 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Hspa9 heat shock protein 9 affects binding ISO Fluorescein-5-isothiocyanate binds to HSPA9 protein CTD PMID:27129696 NCBI chr18:34,937,414...34,954,351
Ensembl chr18:34,937,414...34,954,357
JBrowse link
G Ifng interferon gamma multiple interactions EXP [Dibutyl Phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IFNG protein; [tributyrin co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IFNG protein CTD PMID:29198882 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta affects binding ISO Fluorescein-5-isothiocyanate binds to IKBKB protein CTD PMID:27129696 NCBI chr 8:22,659,205...22,706,589
Ensembl chr 8:22,659,212...22,706,589
JBrowse link
G Ikzf4 IKAROS family zinc finger 4 affects binding ISO Fluorescein-5-isothiocyanate binds to IKZF4 protein CTD PMID:27129696 NCBI chr10:128,630,839...128,669,671
Ensembl chr10:128,630,843...128,669,358
JBrowse link
G Il17re interleukin 17 receptor E affects binding ISO Fluorescein-5-isothiocyanate binds to IL17RE protein CTD PMID:27129696 NCBI chr 6:113,458,699...113,470,758
Ensembl chr 6:113,458,484...113,470,758
JBrowse link
G Il31ra interleukin 31 receptor A affects binding ISO Fluorescein-5-isothiocyanate binds to IL31RA protein CTD PMID:27129696 NCBI chr13:112,521,931...112,580,732
Ensembl chr13:112,519,898...112,594,360
JBrowse link
G Il4 interleukin 4 multiple interactions
increases expression
EXP [Dibutyl Phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IL4 protein; [dibutyrylglycerol analog co-treated with Fluorescein-5-isothiocyanate] affects the secretion of IL4 protein; [tributyrin co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IL4 protein; diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of IL4 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of IL4 protein]] CTD PMID:27871981 PMID:29198882 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Lypd3 Ly6/Plaur domain containing 3 affects binding ISO Fluorescein-5-isothiocyanate binds to LYPD3 protein CTD PMID:27129696 NCBI chr 7:24,636,570...24,641,118
Ensembl chr 7:24,636,550...24,641,118
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of MAFF mRNA CTD PMID:20491607 NCBI chr15:79,346,621...79,359,078
Ensembl chr15:79,346,621...79,359,076
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 affects binding ISO Fluorescein-5-isothiocyanate binds to MAP3K20 protein CTD PMID:27129696 NCBI chr 2:72,285,637...72,442,610
Ensembl chr 2:72,285,637...72,442,610
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK1 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
CTD PMID:27129696 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK3 protein
CTD PMID:27129696 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK8 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
CTD PMID:27129696 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK9 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]
CTD PMID:27129696 NCBI chr11:49,846,728...49,886,421
Ensembl chr11:49,846,751...49,886,421
JBrowse link
G Mt2 metallothionein 2 increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Mybpc1 myosin binding protein C, slow-type affects binding ISO Fluorescein-5-isothiocyanate binds to MYBPC1 protein CTD PMID:27129696 NCBI chr10:88,518,279...88,605,229
Ensembl chr10:88,518,279...88,605,152
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions EXP [Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of NFE2L2 protein CTD PMID:27871981 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression
multiple interactions
ISO
EXP
Fluorescein-5-isothiocyanate results in increased expression of NQO1 mRNA
Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein
diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]; Melatonin inhibits the reaction [diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]]
CTD PMID:20491607 PMID:27871981 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Plce1 phospholipase C, epsilon 1 affects binding ISO Fluorescein-5-isothiocyanate binds to PLCE1 protein CTD PMID:27129696 NCBI chr19:38,481,034...38,785,105
Ensembl chr19:38,481,109...38,785,030
JBrowse link
G Postn periostin, osteoblast specific factor affects binding ISO Fluorescein-5-isothiocyanate binds to POSTN protein CTD PMID:27129696 NCBI chr 3:54,359,267...54,391,041
Ensembl chr 3:54,361,109...54,391,037
JBrowse link
G Pprc1 peroxisome proliferative activated receptor, gamma, coactivator-related 1 affects binding ISO Fluorescein-5-isothiocyanate binds to PPRC1 protein CTD PMID:27129696 NCBI chr19:46,056,526...46,072,909
Ensembl chr19:46,044,886...46,072,915
JBrowse link
G Prkcb protein kinase C, beta increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of PRKCB protein CTD PMID:31958493 NCBI chr 7:122,289,104...122,634,402
Ensembl chr 7:122,288,751...122,634,402
JBrowse link
G Psd4 pleckstrin and Sec7 domain containing 4 affects binding ISO Fluorescein-5-isothiocyanate binds to PSD4 protein CTD PMID:27129696 NCBI chr 2:24,367,558...24,409,870
Ensembl chr 2:24,367,580...24,414,954
JBrowse link
G Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 affects binding ISO Fluorescein-5-isothiocyanate binds to PSMD14 protein CTD PMID:27129696 NCBI chr 2:61,711,694...61,800,376
Ensembl chr 2:61,711,694...61,800,376
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP [diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased phosphorylation of RELA protein; Melatonin inhibits the reaction [[diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased phosphorylation of RELA protein] CTD PMID:27871981 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha affects binding ISO Fluorescein-5-isothiocyanate binds to SCN5A protein CTD PMID:27129696 NCBI chr 9:119,483,404...119,579,030
Ensembl chr 9:119,483,408...119,579,016
JBrowse link
G Skor1 SKI family transcriptional corepressor 1 affects binding ISO Fluorescein-5-isothiocyanate binds to SKOR1 protein CTD PMID:27129696 NCBI chr 9:63,138,164...63,148,961
Ensembl chr 9:63,138,170...63,148,961
JBrowse link
G Slc38a10 solute carrier family 38, member 10 affects binding ISO Fluorescein-5-isothiocyanate binds to SLC38A10 protein CTD PMID:27129696 NCBI chr11:120,103,951...120,151,351
Ensembl chr11:120,103,960...120,151,346
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases phosphorylation
multiple interactions
EXP Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein
diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]]
CTD PMID:27871981 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Stat5a signal transducer and activator of transcription 5A increases phosphorylation
multiple interactions
EXP Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein
diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein]]
CTD PMID:27871981 NCBI chr11:100,859,351...100,885,169
Ensembl chr11:100,859,351...100,885,169
JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions
increases phosphorylation
EXP diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein]] CTD PMID:27871981 NCBI chr10:127,642,955...127,660,987
Ensembl chr10:127,642,986...127,660,957
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 affects binding ISO Fluorescein-5-isothiocyanate binds to TRPA1 protein CTD PMID:27129696 NCBI chr 1:14,872,644...14,918,862
Ensembl chr 1:14,872,648...14,918,862
JBrowse link
G Tslp thymic stromal lymphopoietin increases expression
multiple interactions
EXP Fluorescein-5-isothiocyanate results in increased expression of TSLP protein
diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of TSLP protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of TSLP protein]]
CTD PMID:27871981 NCBI chr18:32,815,383...32,819,799
Ensembl chr18:32,815,383...32,819,797
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of TXN mRNA CTD PMID:20491607 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Usp3 ubiquitin specific peptidase 3 affects binding ISO Fluorescein-5-isothiocyanate binds to USP3 protein CTD PMID:27129696 NCBI chr 9:66,514,639...66,593,148
Ensembl chr 9:66,514,637...66,593,142
JBrowse link
gadodiamide hydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 3830406C13Rik RIKEN cDNA 3830406C13 gene increases expression ISO gadodiamide results in increased expression of C3ORF14 mRNA CTD PMID:20959327 NCBI chr14:12,284,153...12,324,492
Ensembl chr14:12,284,173...12,303,231
Ensembl chr14:12,284,173...12,303,231
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation
multiple interactions
ISO gadodiamide results in increased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of AKT1 protein]
CTD PMID:19561517 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 increases expression ISO gadodiamide results in increased expression of ALDH1A1 mRNA CTD PMID:20959327 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
G Ankrd22 ankyrin repeat domain 22 increases expression ISO gadodiamide results in increased expression of ANKRD22 mRNA CTD PMID:20959327 NCBI chr19:34,122,549...34,166,041
Ensembl chr19:34,121,469...34,166,053
JBrowse link
G Atm ataxia telangiectasia mutated increases expression ISO gadodiamide results in increased expression of ATM mRNA CTD PMID:20959327 NCBI chr 9:53,437,122...53,536,828
Ensembl chr 9:53,439,149...53,536,740
JBrowse link
G Atp8b1 ATPase, class I, type 8B, member 1 increases expression ISO gadodiamide results in increased expression of ATP8B1 mRNA CTD PMID:20959327 NCBI chr18:64,528,979...64,661,272
Ensembl chr18:64,528,967...64,661,267
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 increases expression
increases secretion
ISO gadodiamide results in increased expression of CCL2 mRNA
gadodiamide results in increased expression of CCL2 mRNA; gadodiamide results in increased expression of CCL2 protein
gadodiamide results in increased secretion of CCL2 protein
CTD PMID:20938346 PMID:20959327 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 increases expression ISO gadodiamide results in increased expression of CCL4 protein CTD PMID:20938346 NCBI chr11:83,648,624...83,664,683
Ensembl chr11:83,662,584...83,664,683
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 increases expression ISO gadodiamide results in increased expression of CCL7 protein CTD PMID:20938346 NCBI chr11:82,045,712...82,047,525
Ensembl chr11:82,045,712...82,047,525
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 increases expression
increases secretion
ISO gadodiamide results in increased expression of CXCL10 mRNA
gadodiamide results in increased expression of CXCL10 protein
gadodiamide results in increased secretion of CXCL10 protein
CTD PMID:20938346 PMID:20959327 NCBI chr 5:92,346,638...92,348,889
Ensembl chr 5:92,346,638...92,348,889
JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 increases secretion
increases expression
ISO gadodiamide results in increased secretion of CXCL11 protein
gadodiamide results in increased expression of CXCL11 mRNA
CTD PMID:20959327 NCBI chr 5:92,359,544...92,363,296
Ensembl chr 5:92,359,544...92,365,485
JBrowse link
G Cxcl12 chemokine (C-X-C motif) ligand 12 increases expression ISO gadodiamide results in increased expression of CXCL12 mRNA CTD PMID:20959327 NCBI chr 6:117,168,535...117,181,368
Ensembl chr 6:117,168,535...117,181,367
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 increases expression ISO gadodiamide results in increased expression of CXCL9 mRNA CTD PMID:20959327 NCBI chr 5:92,321,331...92,328,079
Ensembl chr 5:92,321,347...92,328,079
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO gadodiamide results in increased expression of IDO1 mRNA CTD PMID:20959327 NCBI chr 8:24,584,133...24,596,952
Ensembl chr 8:24,584,136...24,597,009
JBrowse link
G Ifi44l interferon-induced protein 44 like increases expression ISO gadodiamide results in increased expression of IFI44L mRNA CTD PMID:20959327 NCBI chr 3:151,758,737...151,762,891
Ensembl chr 3:151,758,737...151,762,892
JBrowse link
G Ifit1bl1 interferon induced protein with tetratricpeptide repeats 1B like 1 increases expression ISO gadodiamide results in increased expression of IFIT1 mRNA CTD PMID:20959327 NCBI chr19:34,592,888...34,662,981
Ensembl chr19:34,592,891...34,601,956
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO gadodiamide results in increased expression of IFIT3 mRNA CTD PMID:20959327 NCBI chr19:34,583,119...34,588,982
Ensembl chr19:34,583,531...34,588,731
JBrowse link
G Ifng interferon gamma increases expression ISO gadodiamide results in increased expression of IFNG mRNA; gadodiamide results in increased expression of IFNG protein CTD PMID:19404939 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il13 interleukin 13 increases expression ISO gadodiamide results in increased expression of IL13 mRNA; gadodiamide results in increased expression of IL13 protein CTD PMID:19404939 NCBI chr11:53,631,323...53,634,702
Ensembl chr11:53,631,324...53,634,702
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO gadodiamide results in increased expression of IL1A protein CTD PMID:20938346 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il4 interleukin 4 increases expression
affects expression
ISO gadodiamide results in increased expression of IL4 protein
gadodiamide affects the expression of IL4 mRNA
CTD PMID:19404939 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il4i1 interleukin 4 induced 1 increases expression ISO gadodiamide results in increased expression of IL4I1 mRNA CTD PMID:20959327 NCBI chr 7:44,836,288...44,840,809
Ensembl chr 7:44,816,387...44,840,809
JBrowse link
G Il6 interleukin 6 affects expression
increases expression
ISO gadodiamide affects the expression of IL6 protein
gadodiamide results in increased expression of IL6 mRNA
CTD PMID:19404939 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Kitl kit ligand increases expression ISO gadodiamide results in increased expression of KITLG protein CTD PMID:20938346 NCBI chr10:100,015,615...100,100,416
Ensembl chr10:100,015,630...100,100,416
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein] CTD PMID:19561517 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein] CTD PMID:19561517 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]
gadodiamide results in increased expression of MMP1 mRNA; gadodiamide results in increased expression of MMP1 protein
CTD PMID:19561517 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression ISO gadodiamide results in increased expression of NOS2 protein CTD PMID:20959327 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nxpe3 neurexophilin and PC-esterase domain family, member 3 increases expression ISO gadodiamide results in increased expression of NXPE3 mRNA CTD PMID:20959327 NCBI chr16:55,839,953...55,897,104
Ensembl chr16:55,839,953...55,895,285
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) increases localization ISO gadodiamide results in increased localization of RELA protein CTD PMID:20959327 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Rhoq ras homolog family member Q increases expression ISO gadodiamide results in increased expression of RHOQ mRNA CTD PMID:20959327 NCBI chr17:86,963,111...87,000,069
Ensembl chr17:86,963,082...87,000,069
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO gadodiamide results in increased expression of RIT1 mRNA CTD PMID:20959327 NCBI chr 3:88,716,842...88,731,048
Ensembl chr 3:88,716,838...88,731,049
JBrowse link
G Rnf125 ring finger protein 125 increases expression ISO gadodiamide results in increased expression of RNF125 mRNA CTD PMID:20959327 NCBI chr18:20,944,615...20,987,359
Ensembl chr18:20,944,625...20,983,862
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression ISO gadodiamide results in increased expression of RSAD2 mRNA CTD PMID:20959327 NCBI chr12:26,442,743...26,456,452
Ensembl chr12:26,442,746...26,456,452
JBrowse link
G Rsl1 regulator of sex limited protein 1 increases expression ISO gadodiamide results in increased expression of ZNF595 mRNA CTD PMID:20959327 NCBI chr13:67,173,182...67,183,499
Ensembl chr13:67,173,182...67,184,044
JBrowse link
G Slc39a10 solute carrier family 39 (zinc transporter), member 10 increases expression ISO gadodiamide results in increased expression of SLC39A10 mRNA CTD PMID:20959327 NCBI chr 1:46,807,544...46,925,776
Ensembl chr 1:46,807,544...46,892,852
JBrowse link
G Spn sialophorin increases expression ISO gadodiamide results in increased expression of SPN mRNA CTD PMID:20959327 NCBI chr 7:127,123,637...127,145,552
Ensembl chr 7:127,132,232...127,137,823
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO gadodiamide results in increased expression of SPP1 protein CTD PMID:20938346 NCBI chr 5:104,435,111...104,441,053
Ensembl chr 5:104,435,118...104,441,050
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO gadodiamide results in increased expression of TGFB1 mRNA; gadodiamide results in increased expression of TGFB1 protein CTD PMID:19404939 PMID:20938346 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression
multiple interactions
ISO gadodiamide results in increased expression of TIMP1 mRNA; gadodiamide results in increased expression of TIMP1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of TIMP1 protein]
CTD PMID:19561517 PMID:20938346 NCBI chr  X:20,870,166...20,874,737
Ensembl chr  X:20,870,166...20,874,735
JBrowse link
G Ubd ubiquitin D increases expression ISO gadodiamide results in increased expression of UBD mRNA CTD PMID:20959327 NCBI chr17:37,193,892...37,196,101
Ensembl chr17:37,193,892...37,196,095
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO gadodiamide results in increased expression of VEGFA mRNA; gadodiamide results in increased expression of VEGFA protein CTD PMID:19404939 PMID:20938346 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Wdr5 WD repeat domain 5 increases expression ISO gadodiamide results in increased expression of WDR5 mRNA CTD PMID:20959327 NCBI chr 2:27,515,147...27,536,535
Ensembl chr 2:27,515,157...27,536,535
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO gadodiamide results in increased expression of XIAP mRNA CTD PMID:20959327 NCBI chr  X:42,059,613...42,109,664
Ensembl chr  X:42,059,679...42,109,656
JBrowse link
G Zfp652 zinc finger protein 652 increases expression ISO gadodiamide results in increased expression of ZNF652 mRNA CTD PMID:20959327 NCBI chr11:95,749,067...95,764,715
Ensembl chr11:95,712,673...95,835,115
JBrowse link
iodixanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 increases expression ISO iodixanol results in increased expression of EDN1 protein CTD PMID:21354280 NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions ISO [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in decreased expression of GCLM mRNA CTD PMID:29860548 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO iodixanol results in increased expression of HAVCR1 mRNA CTD PMID:19104440 NCBI chr11:46,739,822...46,779,578
Ensembl chr11:46,735,080...46,779,578
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of HMGB1 protein CTD PMID:29860548 NCBI chr 5:149,046,702...149,053,057
Ensembl chr 5:149,046,702...149,184,489
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO iodixanol results in increased expression of HMOX1 mRNA
[Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of HMOX1 mRNA
CTD PMID:19104440 PMID:29860548 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Nos2 nitric oxide synthase 2, inducible decreases expression ISO iodixanol results in decreased expression of NOS2 protein CTD PMID:21354280 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Pink1 PTEN induced putative kinase 1 multiple interactions ISO [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PINK1 protein CTD PMID:29860548 NCBI chr 4:138,313,409...138,326,296
Ensembl chr 4:138,313,409...138,326,307
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PRKN protein CTD PMID:29860548 NCBI chr17:10,840,359...12,063,370
Ensembl chr17:10,840,384...12,063,361
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO iodixanol inhibits the reaction [[Drinking Water def